diglycerol phosphate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

diglycerol phosphate: protein stabilizer isolated from Archaeoglobus fulgidus [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

glycerophosphoglycerol(1-) : An organophosphate oxoanion that is the conjugate base of glycerophosphoglycerol; major species at pH 7.3. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID Source	ID
PubMed CID	25202983
CHEBI ID	61933
MeSH ID	M0364034

Synonyms (6)

Synonym
diglycerol phosphate
bis(2,3-dihydroxypropyl) phosphate
glycerophosphoglycerol anion
glycerophosphoglycerol(1-)
CHEBI:61933
Q27131496

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

Class	Description
organophosphate oxoanion	An organic phosphoric acid derivative in which one or more oxygen atoms of the phosphate group(s) has been deprotonated.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (1)

Pathway	Proteins	Compounds
Glycerol Metabolism IV (Glycerophosphoglycerol)	30	30

Research

Studies (11)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	6 (54.55)	29.6817
2010's	4 (36.36)	24.3611
2020's	1 (9.09)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (9.09%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	10 (90.91%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
phosphoserine Phosphoserine: The phosphoric acid ester of serine.	2.44	2	non-proteinogenic alpha-amino acid; O-phosphoamino acid; serine derivative	human metabolite
glycerol Moon: The natural satellite of the planet Earth. It includes the lunar cycles or phases, the lunar month, lunar landscapes, geography, and soil.	7	1	alditol; triol	algal metabolite; detergent; Escherichia coli metabolite; geroprotector; human metabolite; mouse metabolite; osmolyte; Saccharomyces cerevisiae metabolite; solvent
glycerylphosphorylcholine Glycerylphosphorylcholine: A component of PHOSPHATIDYLCHOLINES or LECITHINS, in which the two hydroxy groups of GLYCEROL are esterified with fatty acids. (From Stedman, 26th ed)	2.07	1	glycerophosphocholine
mannose mannopyranose : The pyranose form of mannose.	3.23	1	D-aldohexose; D-mannose; mannopyranose	metabolite
phenyl acetate phenyl acetate: The ester formed between phenol and acetic acid. Don't confuse with phenylacetic acid derivatives listed under PHENYLACETATES.. phenyl acetate : An acetate ester obtained by the formal condensation of phenol with acetic acid.	2.01	1	benzenes; phenyl acetates
glycerophosphoethanolamine glycerol 3-phosphoethanolamine: a membrane lipid degradation product	2.42	2	phosphoethanolamine; sn-glycerol 3-phosphates
ectoine [no description available]	3.23	1	1,4,5,6-tetrahydropyrimidines; carboxamidine; monocarboxylic acid; zwitterion	osmolyte
arachidonic acid icosa-5,8,11,14-tetraenoic acid : Any icosatetraenoic acid with the double bonds at positions 5, 8, 11 and 14.. arachidonate : A long-chain fatty acid anion resulting from the removal of a proton from the carboxy group of arachidonic acid.	2.03	1	icosa-5,8,11,14-tetraenoic acid; long-chain fatty acid; omega-6 fatty acid	Daphnia galeata metabolite; EC 3.1.1.1 (carboxylesterase) inhibitor; human metabolite; mouse metabolite
glycerophosphoserine glycerophosphoserine: RN given refers to (L-serine)-isomer. glycerol 1-phosphoserine : A L-serine derivative consisting of L-serine having a 1-glycerophospho group attached to the side-chain hydroxy function.	2.44	2	glycerol 1-phosphodiester; L-serine derivative; non-proteinogenic L-alpha-amino acid
di-myo-inositol-1,1'-phosphate di-myo-inositol-1,1'-phosphate: isolated from the Archaebacteria Pyrococcus woesei; structure given in first source	2.01	1
lipid a Lipid A: Lipid A is the biologically active component of lipopolysaccharides. It shows strong endotoxic activity and exhibits immunogenic properties.. lipid A : The glycolipid moiety of bacterial lipopolysaccharide (R can be either hydrogen or a fatty acyl group).	2.41	1	dodecanoate ester; lipid A; tetradecanoate ester	Escherichia coli metabolite
mannosylglycerate 2-(alpha-D-mannosyl)-D-glycerate : Conjugate base of 2-(alpha-D-mannosyl)-D-glyceric acid	3.23	1	carbohydrate acid anion

Condition	Relationship Strength	Studies
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.	2.17	1
Corneal Dystrophies [description not available]	2.17	1
Protein Folding Diseases [description not available]	3.04	1
Edema-Proteinuria-Hypertension Gestosis [description not available]	2.07	1
Pre-Eclampsia A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.	2.07	1
Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	2.07	1
Adenoma, beta-Cell [description not available]	2.03	1
Cancer of Pancreas [description not available]	2.03	1
Insulinoma A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA.	2.03	1
Pancreatic Neoplasms Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).	2.03	1

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