Page last updated: 2024-10-19

melatonin and Corneal Dystrophies

melatonin has been researched along with Corneal Dystrophies in 3 studies

Research Excerpts

ExcerptRelevanceReference
"Melatonin treatment reduced the levels of transforming growth factor-β-induced protein (TGFBIp) significantly, and this reduction was suppressed by MG132."1.46Melatonin reduces endoplasmic reticulum stress and corneal dystrophy-associated TGFBIp through activation of endoplasmic reticulum-associated protein degradation. ( Akuzum, B; Choi, SI; Jeong, JB; Kim, EK; Kim, TI; Lee, E; Maeng, YS, 2017)
"Melatonin treatment protected primary cultured normal and GCD2 corneal fibroblasts from paraquat (PQ)-induced oxidative stress and caused increased expression levels of Cu/Zn-superoxide dismutase (SOD1) and glutathione reductase (GR) in both types of cells."1.37Melatonin protects against oxidative stress in granular corneal dystrophy type 2 corneal fibroblasts by mechanisms that involve membrane melatonin receptors. ( Choi, SI; Dadakhujaev, S; Im Kim, T; Kim, EK; Ryu, H, 2011)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, SI2
Lee, E1
Akuzum, B1
Jeong, JB1
Maeng, YS1
Kim, TI1
Kim, EK3
Ahn, JH1
Kim, HD1
Abuzar, SM1
Lee, JY1
Jin, SE1
Hwang, SJ1
Dadakhujaev, S1
Ryu, H1
Im Kim, T1

Other Studies

3 other studies available for melatonin and Corneal Dystrophies

ArticleYear
Melatonin reduces endoplasmic reticulum stress and corneal dystrophy-associated TGFBIp through activation of endoplasmic reticulum-associated protein degradation.
    Journal of pineal research, 2017, Volume: 63, Issue:3

    Topics: Antioxidants; Cell Death; Cells, Cultured; Cornea; Corneal Dystrophies, Hereditary; Drug Evaluation,

2017
Intracorneal melatonin delivery using 2-hydroxypropyl-β-cyclodextrin ophthalmic solution for granular corneal dystrophy type 2.
    International journal of pharmaceutics, 2017, Aug-30, Volume: 529, Issue:1-2

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; beta-Cyclodextrins; Cornea; Corneal Dystrophies, Heredit

2017
Melatonin protects against oxidative stress in granular corneal dystrophy type 2 corneal fibroblasts by mechanisms that involve membrane melatonin receptors.
    Journal of pineal research, 2011, Volume: 51, Issue:1

    Topics: Analysis of Variance; Antioxidants; Blotting, Western; Catalase; Cell Survival; Cells, Cultured; Cor

2011