A fungal infection of the nail, usually caused by DERMATOPHYTES; YEASTS; or nondermatophyte MOLDS.
Excerpt | Reference |
"Onychomycosis is caused by dermatophytes, moulds and yeasts." | ( Chua, HC; Goh, CL; Lim, JT, 1992) |
"Onychomycosis is the most frequent cause of nail diseases." | ( Cohen, JL; Hochman, LG; Holwell, JE; Meyerson, MS; Pappert, AS; Scher, RK, 1992) |
"Onychomycosis is a common disease of the toenails." | ( Serrano, L; Zaias, N, 1989) |
"Treatment of onychomycosis is usually unsatisfactory." | ( Bentley-Phillips, B, 1982) |
"Onychomycosis is one of the most common causes of nail disease and one of the hardest to treat among fungal infections." | ( Montana, JB; Scher, RK, 1994) |
"rubrum." | ( Lucky, AW; Ploysangam, T, 1997) |
"Onychomycosis is the most frequent cause of nail disease and represents 30% of all mycotic infections of the skin." | ( Aly, R; Daniel, CR; DeVillez, R; Elewski, BE; Jacko, M; Moskovitz, BL; Odom, RB; Oleka, N; Scher, RK; Zaias, N, 1997) |
"Onychomycosis is primarily caused by dermatophyte fungi but occasionally by yeasts and non-dermatophytic moulds." | ( Richardson, MD, 1997) |
"Onychomycosis is an increasing problem with limited therapeutic options." | ( Arlette, JP; Birnbaum, JE; Cloutier, R; Danby, FW; Drake, LA; Elewski, BE; Evans, S; Garnis-Jones, S; Giroux, JM; Gratton, D; Gulliver, W; Hull, P; Jones, HE; Journet, M; Krol, AL; Leyden, JJ; Maddin, SC; Ross, JB; Savin, RC; Scher, RK; Shear, NH; Sibbald, GR; Tawfik, NH; Tolpin, M; Zaias, N, 1997) |
"Onychomycosis is one of the most common nail disorders seen by dermatologists." | ( Elewski, BE, 1997) |
"Onychomycosis is caused primarily by dermatophytes, Candida species, and nondermatophytic molds." | ( Evans, EG, 1998) |
"Onychomycosis is a common infectious disease." | ( Seebacher, C, 1998) |
"Onychomycosis is a prevalent infection of the nail caused primarily by dermatophytes." | ( Aly, R; Breneman, D; Bucko, AD; Elewski, BE; Feingold, DS; Greer, DL; Konnikov, N; Levine, N; Lowe, NJ; Morman, MR; Odom, RB; Pinnell, S; Rich, P; Savin, RC; Scher, RK; Shupack, JL; Smith, EB; Tschen, EH, 1998) |
"Onychomycosis is a prevalent infection of the nail caused primarily by dermatophytes." | ( Babel, D; Breneman, D; Bucko, AD; Drake, L; Elewski, BE; Ellis, CN; Greer, DL; Hanifin, JM; Kang, S; Katz, HI; Leyden, JJ; Ling, MR; Martin, AG; McDonald, CJ; Morman, MR; Muglia, J; Pariser, DM; Pariser, RJ; Rich, P; Savin, RC; Scher, RK; Shupack, JL; Stewart, DM; Tschen, EH; Webster, G, 1998) |
"Four types of onychomycosis are recognized based on the site and pattern of fungal invasion." | ( Elewski, BE, 1998) |
"Onychomycosis is an increasingly common and recalcitrant fungal nail infection world-wide." | ( Ahmad, SA; Ahmadpour, OA; Shamsi, S; Syed, TA, 1998) |
"Pediatric onychomycosis is a rare disease and it is difficult to decide in such cases whether or not an oral antifungal is indicated." | ( Hiruma, M; Kawai, M; Maeng, DJ; Ogawa, H; Takimoto, R, 1999) |
"Onychomycosis is less common in children than in adults." | ( De Rosso, JQ; Gupta, AK, 1999) |
"Onychomycosis is common in adults and constitutes 20% of all nail disease." | ( Anderson, RR; Dwyer, P; Gonzalez, S; Hongcharu, W, 2000) |
"Onychomycosis is a common fungal disease infecting up to 20% of the population over age 40." | ( Bradley, MC; Elewski, BE; Ghannoum, MA; Isham, N; Leidich, S, 1999) |
"Onychomycosis is a relatively common condition affecting toenails more than fingernails." | ( Baran, R; Fleckman, P; Gupta, AK, 2000) |
"Today onychomycosis is found in up to 10% of human beings." | ( Korting, HC; Schaller, M, 2001) |
"Superficial white onychomycosis is exceptional in children, although a few anecdotal cases have been reported in the literature." | ( Almagro, M; del Pozo, J; Fonseca, E; García-Silva, J; Peña-Penabad, C, 2001) |
"Onychomycosis is a fungal infection of the nail unit, most commonly caused by the anthropophilic dermatophyte fungi." | ( Hay, RJ, 2001) |
"Although onychomycosis is often observed in diabetics, there have been no large studies of its epidemiology in this patient group in India." | ( Bhansali, A; Chakrabarty, A; Dogra, S; Kumar, B, 2002) |
"Therapy for onychomycosis is difficult because a complete cure requires long-term treatment." | ( Ito, T; Majima, T; Nakashima, T; Nozawa, A, 2002) |
"Onychomycosis is often considered only as a cosmetic diagnosis." | ( Jones, ED, 2003) |
"Toenail onychomycosis is a common disease that can have serious adverse effects on the quality of life (QOL) of patients." | ( Dowlati, Y; Firooz, A; Khamesipour, A, 2003) |
"Onychomycosis is a common problem seen in clinical practice." | ( Koestenblatt, EK; Najarian, L; Tishler, HR; Tutrone, WD; Weinberg, JM, 2003) |
"Onychomycosis is found more frequently in the elderly and in more males than females." | ( Scheinfeld, NS; Weinberg, JM, 2003) |
"Onychomycosis is an infection of the finger-and/or toenails by fungal microorganisms." | ( Reinel, D, 2004) |
"The prevalence of onychomycosis is higher in certain high-risk populations, such as the immunocompromised, diabetics and human immunodeficiency virus (HIV)-positive patients." | ( Bakshi, R; Cribier, BJ, 2004) |
"Onychomycosis is a common nail disease that is often chronic, difficult to eradicate, and has a tendency to recur." | ( Gupta, AK; Johnson, AM; Ryder, JE, 2004) |
"Onychomycosis is mainly caused by dermatophytes, but yeasts and nondermatophyte molds have also been implicated, giving rise to diverse clinical presentations." | ( Agrawal, SK; Garg, A; Kaushal, GP; Pathak, KP; Singh, M; Venkatesh, V, 2004) |
"Treatment of onychomycosis is associated with substantial disease reappearance rates." | ( Gupta, AK; Lynch, LE, 2004) |
"Onychomycosis is a relatively common disease accounting for up to 50% of all nail disorders and its prevalence rises with age." | ( Baran, R; Kaoukhov, A, 2005) |
"Onychomycosis is usually caused by F." | ( Hattori, N; Li, W; Misawa, Y; Okuzumi, K; Shirai, A; Sugiura, Y; Tamaki, K; Yokoyama, K, 2005) |
"Onychomycosis is prevalent in the Canadian population, and risk factors, such as old age and diabetes, are increasing." | ( Gupta, AK; Lynch, LE; Schouten, JR, 2005) |
"Onychomycosis is a public health concern because of its high world wide prevalence, and its potential for spread of fungal elements to others." | ( Nowicki, R, 2001) |
"Onychomycosis is a fungal infection of the fingernails and toenails that results in thickening, discoloration, splitting of the nails and lifting of the nail from the nail bed." | ( Alley, MR; Baker, SJ; Beutner, KR; Plattner, J, 2007) |
"Onychomycosis is a common adult human mycosis, and dermatophytes of the Trichophyton genera are the most common causative agent." | ( Barros, MEDS; Hamdan, JS; Santos, DA, 2007) |
"Onychomycosis is common, accounting for up to 50% of all nail disorders." | ( Baran, R; de Berker, D; Faergemann, J; Kaufmann, R; Kerrouche, N; Lecha, M; Sidou, F; Sigurgeirsson, B, 2007) |
"Onychomycosis is a challenging fungal infection to treat topically, likely due to the unique properties of the nail plate." | ( Akama, T; Baker, SJ; Barbadillo, S; Cashmore, AK; Hold, KM; Hui, X; Maibach, HI; Plattner, JJ; Sanders, V; Wester, RC; Zhang, YK, 2007) |
"Onychomycosis is a rare disease in children with an estimated prevalence ranging from 0% to 2." | ( Ginter-Hanselmayer, G; Smolle, J; Weger, W, 2008) |
"Onychomycosis is a common cause of deformed nails." | ( Billings, SD; D'Hue, Z; Perkins, SM, 2008) |
"Onychomycosis is a complication of diabetes mellitus (DM), which has a deleterious impact on the quality of life." | ( Chang, SJ; Chen, HC; Hsiao, JY; Hsieh, MC; Hsu, SC; Lin, SR; Tien, KJ, 2008) |
"Onychomycosis is an important public health problem because of the increase in immunosuppressive states." | ( Aggarwal, P; Capoor, MR; Deb, M; Ramesh, V; Sarma, S, 2008) |
"Onychomycosis is one of the most common infections of the nail." | ( Ceballos, JD; Erchiga, VC; Falcón, CS; Falcón, Mdel M; Florencio, VD; xOrtega, SC, 2009) |
"Onychomycosis is the most common single cause of nail dystrophy and has a marked impact on quality of life." | ( Cornelius, L; Nunley, KS, 2008) |
"Onychomycosis is a dermatological problem of high prevalence that mainly affects the hallux toenail." | ( da Cunha, MM; Dornelas-Ribeiro, M; dos Santos, LP; Rozental, S; Vermelho, AB, 2009) |
"Onychomycosis is one of the most common nail disorders." | ( Barber, J; Barber, K, 2009) |
"Onychomycosis is a common disorder of nails caused by diverse spectrum of fungi ranging from dermatophytes to nondermatophyte molds and yeasts." | ( Kimball, AB; Kumar, S, 2009) |
"Background Onychomycosis is a common disease; topical treatment is usually poorly effective, while systemic treatment is more effective but may be associated with side-effects." | ( Amichai, B; Mosckovitz, R; Nitzan, B; Shemer, A, 2010) |
"Onychomycosis is one of the commonest dermatological diseases worldwide." | ( Bueno, JG; Gallego, M; Martinez, C; Mesa, AC; Sanclemente, G; Zapata, B, 2010) |
"Onychomycosis is the most common nail disease in adults." | ( Reza Kermanshahi, T; Rhatigan, R, 2010) |
"Onychomycosis is a common disease." | ( Amichai, B; Barak, D; Ben-Yaakov, S; Mosckovitz, R; Nitzan, B; Royz, M; Shemer, A; Sholto, O; Trau, H, 2010) |
"Onychomycosis is even more challenging to treat as relapses and re-infections are common." | ( Kerrouche, N; Olafsson, JH; Sidou, F; Sigurgeirsson, B; Steinsson, JT, 2010) |
"Onychomycosis is a relatively common disease accounting for up to 50% of all nail disorders." | ( Amichai, B; Grunwald, MH; Nathansohn, N; Shemer, A; Trau, H, 2010) |
"Onychomycosis is a frequent nail disease caused by dermatophytes, yeasts, and nondermatophyte molds." | ( Vera-Cabrera, L; Welsh, E; Welsh, O, 2010) |
"Onychomycosis is the nail infection caused by a wide spectrum of fungi species, including yeasts, dermatophytes and filamentous fungi non-dermatophytes (FFND)." | ( Ataides, FS; Chaul, MH; Costa, CR; El Essal, FE; Fernandes, OF; Silva, MR; Souza, LK, 2012) |
"Onychomycosis is a fungal infection of the nail apparatus that affects 10 - 30% of the global population." | ( Gupta, AK; Simpson, FC, 2012) |
"Onychomycosis is difficult to cure as this requires eradication of the primary infection and protection of new areas of growth from reinfection." | ( Emtestam, L; Kaaman, T; Rensfeldt, K, 2012) |
"Onychomycosis is a common nail infection, often resulting in nail plate damage and deformity." | ( Elewski, BE; Ieda, C; Olin, JT; Pariser, DM; Pillai, R; Pollak, R; Ramakrishna, T; Rich, P; Senda, H; Smith, K; Watanabe, S, 2013) |
"Onychomycosis is a fungal infection which is the most common disease of nail plate." | ( Özer, Ö; Tanrıverdi, ST, 2013) |
"Onychomycosis is a common fungal nail infection in adults that is difficult to treat." | ( Fothergill, A; Jo Siu, WJ; Nakamura, T; Pillai, R; Senda, H; Sone, D; Tatsumi, Y, 2013) |
"Onychomycosis is a common nail infection that is difficult to treat successfully." | ( Bucko, AD; Kawabata, H; Oizumi, N; Olin, JT; Pillai, R; Tschen, EH, 2013) |
"Toenail onychomycosis is highly prevalent, with 14-28% of people aged 60 or over suffering from the disease." | ( Baran, R; Bulai-Livideanu, C; Coubetergues, H; Lahfa, M; Ortonne, JP; Paul, C; Piraccini, BM; Richert, B; Sibaud, V; Szepietowski, JC; Tosti, A; Voisard, JJ, 2013) |
"Onychomycosis is a common fungal infection most often affecting the toenails." | ( Delcker, A; Hay, R; Kurka, P; Merk, HF; Querner, S; Tietz, HJ, 2013) |
"Onychomycosis is a common fungal infection of the nail plate and bed that affects up to 14% of the population and can have a substantial impact on the quality of life of those affected." | ( Hafeez, F; Hui, X; Maibach, H; Rosenthal, B; Selner, M, 2014) |
"Onychomycosis is effectively treated with terbinafine and itraconazole." | ( Malahias, S; Raterink, K; Sigurgeirsson, B; van Rossem, K, 2013) |
"Onychomycosis is a fungal nail disease and is one of the major onychopathy worldwide." | ( Bagnato, VS; Inada, NM; Kurachi, C; Silva, AP, 2013) |
"Onychomycosis is a widespread problem." | ( Becker, C; Bershow, A, 2013) |
"Onychomycosis is rare in children, but the occurrence seems to be increasing." | ( Arendrup, MC; Haugaard, LK; Saunte, DM; Skov, L, 2013) |
"Onychomycosis is a common superficial fungal infection, which usually caused by dermatophytes, yeast and non-dermatophytic moulds." | ( Chen, H; Chen, M; Liao, W; Pan, W; Zhou, J, 2014) |
"Toenail onychomycosis is a common disease with limited treatment options, as treatment failures and relapses frequently are encountered." | ( Tosti, A, 2013) |
"Onychomycosis is a very common fungal infection of the nail apparatus; however, it is very hard to treat, even when the causative agent is identified, and usually requires prolonged systemic antifungal therapy." | ( de Sá, DC; Lamas, AP; Tosti, A, 2014) |
"Onychomycosis is a fungal infection mostly induced by dermatophytes such as Trichophyton rubrum." | ( Müller-Goymann, CC; Täuber, A, 2014) |
"Onychomycosis is a common fungal nail disease that is difficult to treat topically due to the deep location of the infection under the densely keratinized nail plate." | ( Arakawa, Y; Hosaka, S; Jo Siu, W; Katafuchi-Nagashima, M; Pillai, R; Sugimoto, N; Sugiura, K; Tatsumi, Y, 2014) |
"Onychomycosis is a challenging nail disease that is difficult to treat due to the thickness and impermeability of the nail plate." | ( Daigle, D; Gupta, AK, 2014) |
"Onychomycosis is a fungal infection of the nail apparatus that can be challenging to treat due to the modest efficacy of existing antifungal therapies and a high rate of relapse and recurrence." | ( Elewski, BE; Gupta, AK; Ieda, C; Kang, R; Kawabata, H; Olin, JT; Pillai, R; Sugarman, JL; Watanabe, S, 2014) |
"Laser Treatment of onychomycosis is a quick and easy method without complications." | ( Galvan Garcia, HR, 2014) |
"Onychomycosis is difficult to cure." | ( Luo, D; Miao, X; Xu, Y; Zhou, B, 2014) |
"Onychomycosis is fungal infection of one or more of the nail units." | ( Ahmed, QM; Fazili, T; Hassan, I; Jeelani, N; Jeelani, S; Lanker, AM, 2015) |
"Toenail onychomycosis is a common disease with limited treatment options; treatment failure and relapse are frequently encountered." | ( Pollak, RA, 2014) |
"Onychomycosis is a very common nail disorder seen in dermatological practice." | ( Kircik, LH, 2014) |
"Onychomycosis is a chronic fungal infection of the nails that is largely underdiagnosed in developing countries such as India due to poor health care facilities." | ( Adekhandi, S; Dimri, D; Juyal, D; Pal, S; Sharma, M; Sharma, N, 2015) |
"Onychomycosis is an often overlooked and/or undertreated disease." | ( Bhatia, N; Friedlander, SF; Gupta, AK; Kircik, L; Rosen, T; Stein Gold, L; Zirwas, MJ, 2015) |
"Onychomycosis is a common nail disease, especially in older patients." | ( Bunyaratavej, S; Manuskiatti, W; Thanomkitti, K; Wanitphakdeedecha, R, 2016) |
"Onychomycosis is a common nail infection that often co-exists with tinea pedis." | ( Lipner, SR; Scher, RK, 2015) |
"Onychomycosis is a common fungal infection of the nail unit that results in discoloration, subungual debris, thickening, onycholysis, and often pain and impairment of mobility." | ( Canavan, T; Cantrell, W; Elewski, B, 2015) |
"Onychomycosis is a fungal infection of nail unit that is caused by dermatophytes." | ( Hilmioğlu Polat, S; Kandiloğlu, G; Özer, Ö; Tanrıverdi, ST; Yeşim Metin, D, 2016) |
"Onychomycosis is a fungal infection of the nail unit." | ( Pajaziti, L; Vasili, E, 2015) |
"Onychomycosis is a common fungal infection of nails which is mainly caused by dermatophyte species and less often by yeasts and non-dermatophyte molds." | ( Abastabar, M; Armaki, MT; Falahati, M; Farahyar, S; Ghasemi, Z; Ghojoghi, A; Hedayati, MT; Hoseinnejad, A; Roudbary, M, 2016) |
"The immunology of onychomycosis is poorly understood." | ( Atri, D; Bhattacharya, SN; Dar, SA; Das, S; Gupta, C; Ramachandran, VG; Saha, R, 2016) |
"Onychomycosis is a fungal nail plate infection that has been increasing in prevalence." | ( Finch, J; Jinna, S, 2015) |
"Onychomycosis is the most common disease of the nail in adults." | ( Cohen, J; Joyce, C; Mikailov, A; Mostaghimi, A, 2016) |
"Onychomycosis is a fungal nail infection that is difficult to treat due to poor accessibility of drugs into the nail plate." | ( Cernea, M; Gupta, AK, 2016) |
"Fusarium onychomycosis is not uncommon in tropical countries but is worth reporting." | ( Dalal, BD; Modak, MS; Shah, SR, 2016) |
"As onychomycosis is unsightly, this study clinically evaluated whether the antifungal efficacy of amorolfine 5% nail lacquer (NL) was affected by a masking, natural-coloured, cosmetic nail varnish applied 24 h later; in vitro investigations were also performed." | ( Ghannoum, MA; Kerrouche, N; Osman-Ponchet, H; Sidou, F; Sigurgeirsson, B, 2016) |
"Onychomycosis is a fungal infection of the nail caused by dermatophytes, yeasts, and nondermatophyte fungi." | ( Dorval, E; Grace, Y; Machin, JD; Poulakos, M, 2017) |
"Onychomycosis is a common and difficult-to-treat fungal infection of the nail unit that gradually leads to dystrophic changes of the nail plate and nail bed." | ( Chanda, S; Coronado, D; Del Rosso, J; Zane, LT, 2016) |
"Onychomycosis is a stubborn fungal infection of the nails that can be difficult to effectively manage." | ( Foley, KA; Gupta, AK; Gupta, G, 2015) |
"Onychomycosis is a widespread public health problem, in which T." | ( El-Elsayyad, H; El-Mashad, N; Noaman, I; Soliman, M; Tawfik, AA, 2016) |
"Onychomycosis is a prevailing disease caused by fungal infection of nails that mostly affects athletes and the elderly." | ( Choi, JY; Go, TG; Han, SD; Jun, JH; Kang, MH; Kim, JO; Son, MW; Thapa, RK; Yong, CS, 2016) |
"Onychomycosis is a fungal nail infection that accounts for half of all nail diseases." | ( Gupta, AK; Versteeg, SG, 2016) |
"Onychomycosis is difficult to treat topically due to the deep location of the infection under the densely keratinized nail plate." | ( Hashimoto, T; Konno, Y; Matsuda, Y; Sugiura, K; Tatsumi, Y; Ueda, A, 2016) |
"Onychomycosis is a fungal infection of the nail plate and subungual area." | ( Li, Y; Xu, J; Zhao, JY; Zhuo, FL, 2016) |
"Onychomycosis is a common fungal nail infection that responds poorly to antifungals." | ( Aspiroz, C; Frías, MP; García-Doval, I; Gilaberte, Y; Rezusta, A; Robres, MP, 2017) |
"Onychomycosis is considered an age-related infection with increasing prevalence in the older age groups." | ( García-Romero, MT; Solís-Arias, MP, 2017) |
"Onychomycosis is a rare nail disorder in early childhood, while onychomadesis is a periodic idiopathic, non-inflammatory disease that affects the nail matrix and is common in children especially in those who suffer from viral infections." | ( Chen, Z; De Hoog, GS; Feng, P; Huang, H; Lai, W; Li, M; Lu, C; Wei, L; Xue, R; Yin, S, 2017) |
"Onychomycosis is an infection of the nail unit by a fungus." | ( Atashili, J; Eba, M; Fuh, AN; Kwenti, ET; Mouliom, RN; Nchanji, GT; Njunda, AL, 2016) |
"Onychomycosis is common in diabetics in Fako signifying the need for regular screening by either microscopy or culture." | ( Atashili, J; Eba, M; Fuh, AN; Kwenti, ET; Mouliom, RN; Nchanji, GT; Njunda, AL, 2016) |
"Onychomycosis is a fungal infection of the nail apparatus caused by dermatophytes, Candida and non-dermatophytic molds." | ( Yamaguchi, H, 2016) |
"Onychomycosis is a fungal infection of the nail unit that may lead to dystrophy and disfigurement over time." | ( Halteh, P; Lipner, SR; Scher, RK, 2016) |
"Onychomycosis is a highly prevalent disease worldwide." | ( Cardona-Arias, JA; Velasquez-Agudelo, V, 2017) |
"Onychomycosis is a fungal nail infection." | ( Baltazar, D; Bordado, JM; Dos Santos, RG; Gonçalves, L; Gordo, PM; Gregorí Valdes, BS; Marto, J; Ribeiro, HM; Salgado, A; Serro, AP; Silva, A, 2017) |
"Onychomycosis is a highly prevalent and intractable disease." | ( Kishida, H; Okubo, A; Watanabe, S, 2017) |
"Onychomycosis is a common progressive fungal infection of the nail bed, matrix, or plate leading to destruction and deformity of the toenails and fingernails." | ( Cook-Bolden, FE; Lin, T, 2017) |
"Onychomycosis is a fungal nail infection caused primarily by dermatophytes." | ( Ghannoum, M; Isham, N; Leal, L; Markinson, B; Mukherjee, P; Rosso, JD, 2018) |
"Considering onychomycosis is a difficult to treat infection, and little is known about the genetic variability and susceptibility pattern of Fusarium spp." | ( Corrêa, C; Fuentefria, AM; Goldani, LZ; Heidrich, D; Rosa, PD; Scroferneker, ML; Vettorato, G, 2017) |
"Onychomycosis is a common nail disease with numerous etiological pathogens." | ( Kunalan, S; Ramalingam, R; Tang, MM, 2017) |
"Toenail onychomycosis is a chronic fungal infection that often requires prolonged treatment in order to effectively manage pathogenic organisms and obtain a clear nail." | ( Aly, R; Gupta, AK; Vlahovic, T; Winter, T; Zane, LT, 2017) |
"Onychomycosis is a common fungal infection in dermatology clinics." | ( Li, Q; Wang, A; Wang, H; Yue, X, 2018) |
"Onychomycosis is a common disease that remains difficult to treat despite the introduction of new topical agents." | ( Ilie, C; Pollak, RA, 2017) |
"Onychomycosis is a common disease that remains a difficult disorder to treat despite the introduction of new topical agents; and not all patients are cured." | ( Cantrell, W; Elewski, BE; Lin, T, 2018) |
"Onychomycosis is a fungal infection of the nail primarily caused by the dermatophytes Trichophyton rubrum and Trichophyton mentagrophytes." | ( Ghannoum, M; Gupta, AK; Markinson, B; Rock, F; Rycerz, A; Winter, T, 2018) |
"Onychomycosis is a fungal nail infection caused by dermatophytes, nondermatophytes, and yeast, and is the most common nail disorder seen in clinical practice." | ( Lipner, SR; Scher, RK, 2019) |
"Onychomycosis is a common but difficult to treat nail disorder." | ( Bonhert, K; Dorizas, A; Sadick, NS, 2019) |
"Onychomycosis is a chronic fungal infection of the nails, and the treatment has been proven to be a challenge to healthcare professionals." | ( Abd El-Aal, EB; Abdo, HM; Eldestawy, MT; Ibrahim, SM, 2019) |
"Onychomycosis is a fungal nail infection caused primarily by the dermatophytes Trichophyton rubrum and Trichophyton interdigitale or, less frequently, by molds like Aspergillus spp." | ( Däschlein, G; Gross, Z; Mahammed, A; Preuß, A; Röder, B; Saltsman, I; Shamali, N, 2018) |
"Identification of onychomycosis is mainly based on clinical diagnosis with auxiliary diagnostic methods such as potassium hydroxide (KOH) microscopy, periodic acid-Schiff staining or fungal culture." | ( Ho, WT; Li, Y; Yang, S, 2019) |
"Onychomycosis is most commonly caused by dermatophytes." | ( Chan, JFW; Chan, KF; Cheung, M; Fung, KSC; Lai, CKC; Lau, ECL; Lau, SKP; Lee, CY; Li, X; Ng, RHY; Ngan, AHY; Tang, JYM; Tsang, CC; Woo, PCY, 2019) |
"Onychomycosis is an opportunistic fungal infection often infecting people with compromised immune system." | ( Amra, K; Momin, M, 2019) |
"Onychomycosis is a common chronic-resistant nail disease." | ( Aliweh, HA; El-Tatawy, RA; Hegab, DS; Shams Eldeen, MA; Talaat, RAZ, 2019) |
"Onychomycosis is a common disorder that is difficult to cure." | ( Brodell, RT; Daggett, C; Daniel, CR; Jackson, J, 2019) |
"Onychomycosis is a fungal infection of the nail caused by dermatophytes, yeasts and nondermatophyte moulds that accounts for approximately 50% of all nail-related disease." | ( Foley, KA; Gupta, AK; Mays, RR; Piguet, V; Shear, NH, 2020) |
"Onychomycosis is an important medical disorder affecting both health and quality of life of patients." | ( Abdo, HM; Ebadah, MA; Ibrahim, SM; Zaki, AM, 2020) |
"Onychomycosis is a progressive fungal infection of the nails that involves the deeper nail layer and nail bed." | ( Koo, KT; Lee, BC; Na, J; Pangeni, R; Park, JW, 2019) |
"Onychomycosis is a chronic, fungal infection of the nails." | ( Bamimore, MA; Foley, KA; Gupta, AK; Piguet, V; Shear, NH; Stec, N, 2020) |
"Onychomycosis is the most common nail condition and when left untreated, has esthetic, physical and emotional-social sequelae." | ( Lipner, SR; Wang, Y, 2021) |
"Onychomycosis are fungal nail infections comprising of about 50% of onychopathies and are commonly caused by dermatophytes." | ( Berlitz, SJ; Canto, RFS; Fuentefria, AM; Guerreiro, ICK; Kaminski, TFA; Quatrin, PM, 2020) |
"Onychomycosis is especially common among diabetic patients." | ( Hamedani, E; Harkless, L; Navarrete, R; Seun, J; Shofler, D; Thamby, R, 2020) |
"Onychomycosis is a fungal infection of the nail, causing discoloration and thickening of the affected nail plate, and is the most common nail infection worldwide." | ( Gupta, AK; Piguet, V; Piraccini, BM; Shear, NH; Stec, N; Summerbell, RC; Tosti, A, 2020) |
"Onychomycosis is the most common nail disorder." | ( Abd Elhameed, MI; Abu El-Hamd, M; Saleh, R; Shalaby, MFM, 2020) |
"Onychomycosis is a difficult to treat condition whose prevalence is increasing." | ( Gupta, AK; Piguet, V; Shear, NH; Venkataraman, M, 2020) |
"Onychomycosis is a fungal disease that affects the fingernails and toenails and is predominantly caused by dermatophytes." | ( Brand, S; Curelop, S; Degenhardt, T; Elewski, B; Pollak, R; Schotzinger, R; Tavakkol, A, 2021) |
"Clinical signs of onychomycosis are longitudinal yellow and white striae on the nail plate and are diagnosed by KOH direct microscopic examination." | ( Asahina, Y; Sato, T; Toshima, S; Yaguchi, T; Yamazaki, K, 2020) |
"Onychomycosis is the most common nail disorder and is associated with diagnostic challenges." | ( Chang, SE; Han, SS; Kim, YJ; Yang, HJ, 2020) |
"Onychomycosis is a fungal infection of the nail." | ( Cai, W; Huang, H; Li, J; Lu, S; Qin, J; Xi, L; Yang, S; Zhang, J; Zhang, Y, 2021) |
"Onychomycosis is a recalcitrant fungal nail infection." | ( Gupta, AK; Kempers, SE; Pariser, DM; Rensfeldt, K; Surprenant, MS; Tavakkol, A, 2021) |
"Onychomycosis is a common chronic fungal infection of the nails caused by dermatophytes, yeasts, and non-dermatophyte filamentous fungi." | ( El-Hawary, EE; Fawzy, MM; Nofal, A, 2020) |
"Onychomycosis is an uncommon condition in children with increasing global prevalence." | ( Gupta, AK; Piguet, V; Shear, NH; Venkataraman, M, 2022) |
"Onychomycosis is a fungal infection of the nail plate or nail bed that leads to the gradual destruction of the nail." | ( Assunção, CB; Caligiorne, RB; de Figueiredo, SM; Johann, S; La Santrer, EFR; Rodrigues, AM; Soares de Abreu, AG, 2020) |
"Onychomycosis is the most common nail disease seen in clinical practice." | ( Lipner, SR; Ricardo, JW, 2020) |
"Onychomycosis is a common and intractable superficial mycosis that occurs worldwide." | ( Hasegawa, N; Shibuya, K, 2020) |
"Onychomycosis is a disease that affects many adults, whose treatment includes both oral and topical therapies with low cure rates." | ( Böszörményi, A; Das, S; Kőszegi, T; Nagy, S; Pál, S; Salem, A; Széchenyi, A; Vörös-Horváth, B, 2020) |
"Onychomycosis is considered a stubborn nail fungal infection that does not respond to conventional topical antifungal treatments." | ( Abobakr, FE; Elwazzan, VS; Fayez, SM; Sakran, W, 2021) |
"Onychomycosis is the most prevalent nail disease." | ( Bahurupi, Y; Chauhan, P; Divyalakshmi, C; Hazarika, N; Kansal, NK, 2021) |
"Onychomycosis is a chronic fungal infection of the nails and is commonly observed in adults, especially the elderly, those who are diabetic, have poor peripheral circulation, and are immunocompromised; however, onychomycosis in children is being reported more frequently, especially in older children." | ( Abramovits, W; Guenin, EP; Gupta, AK; Venkataraman, M, 2021) |
"Onychomycosis is defined as infection caused by nondermatophytic molds and yeasts: tinea unguium is caused by dermatophytes." | ( Ataii, M; Laffleur, F; Nagler, M, 2021) |
"Onychomycosis is a chronic fungal infection of the fingernail or toenail bed leading to brittle, discolored, and thickened nails." | ( Frazier, WT; Santiago-Delgado, ZM; Stupka, KC, 2021) |
"Toenail onychomycosis is a common condition that is equally challenging for podiatrists and patients." | ( Garoufalis, MG, 2022) |
"Onychomycosis is a difficult-to-treat fungal nail infection whose treatment can involve systemic or topical antifungal approaches." | ( Blume-Peytavi, U; Carreño, C; Falqués, M; Galván, J; Tamarit, ML; Tebbs, V; Tosti, A, 2022) |
"Onychomycosis is a fungal nail infection that causes nail discoloration, nail plate thickening, and onycholysis." | ( Gupta, AK; Talukder, M, 2022) |
"Onychomycosis is the main cause of toenail disorders and is produced by a fungal infection." | ( Marcos-Tejedor, F; Mayordomo, R; Santos-Carnicero, N, 2021) |
"onychomycosis is defined as a fungal infection of the nails." | ( Rafalimanana, C; Rakoto-Alson, OA; Rakotoarivelo, ZH; Rakotozandrindrainy, N; Razanakolona, LR; Tsatoromila, FAM; Zafindraibe, NJ, 2021) |
"Onychomycosis is notoriously strenuous to cure." | ( Adin, SN; Ali, A; Aqil, M; Gupta, I; Mujeeb, M; Sultana, Y, 2022) |
"Onychomycosis is the most common fungal infection of the nail affecting the skin under the fingertips and the toes." | ( Agrawal, AK; Dehari, D; Kumar, D; Mehata, AK; Parbat, D; Priya, V; Singh, S; Srivastava, AK, 2022) |
"Onychomycosis is a nail infection caused by Trichophyton interdigitale and other fungi, which can be treated with topical amorolfine (AMR) and ciclopirox olamine (CPX)." | ( Almeida, BCT; Baltazar, LM; Carmo, PHF; Dornelas, JCM; Ferreira, GF; Freitas, GJC; Peres, NTA; Santos, DA, 2022) |
"Onychomycosis is a nail infection, which can be treated with amorolfine and ciclopirox olamine." | ( Almeida, BCT; Baltazar, LM; Carmo, PHF; Dornelas, JCM; Ferreira, GF; Freitas, GJC; Peres, NTA; Santos, DA, 2022) |
"Treatment of onychomycosis is challenging by virtue of the impact of nail disfigurement, the location of the fungi within the nail and reported antifungal resistance worldwide." | ( Omar, SS; Sobhy, N; Talla Eweed, H, 2022) |
"Diagnosis of onychomycosis is based on potassium hydroxide (KOH), direct smear, culture, and polymerase chain reaction." | ( Barzilai, A; Baum, S; Greenbaum, H; Huszar, M; Ikher, S; Shemer, A, 2023) |
"Onychomycosis is the most common disease affecting the nail unit and accounts for at least 50% of all nail diseases." | ( Amorim, GMW; Andrade-Júnior, FP; Duarte, SS; Ferreira, RC; Gouveia, RG; Lima, EO; Medeiros, CIS; Oliveira, NR; Oliveira-Filho, AA; Silva, DKF, 2023) |
"Onychomycosis is a fungal infection of the nail unit caused by various species of dermatophytes, non-dermatophytic moulds or yeasts." | ( Nagesha, PC; Rangegowda, SM; Ravikumar, BC; Shetty, P; Vinay, KN, 2023) |
"Onychomycosis is a prevalent condition affecting the United States and global population." | ( Issa, NT; Kircik, L, 2023) |
"Onychomycosis is difficult to treat due to long treatment durations, poor efficacy rates of treatments, high relapse rates, and safety issues when using systemic antifungal agents." | ( Cooper, EA; Gupta, AK; Haas-Neill, S; Polla Ravi, S; Wang, T, 2023) |
"Onychomycosis is the most common infective nail disease, and treatment includes topical and systemic antifungal medications." | ( Choi, SY; Kim, BJ; Ko, EJ; Seok, J; Shin, SH; Yoo, KH, 2023) |
Excerpt | Reference |
"A problem in the treatment of onychomycosis is the lengthy duration of therapy." | ( Cauwenbergh, G; De Doncker, P; Heykants, J; Roseeuw, D; Van Cutsem, J; Van de Velde, V; Willems, J; Willemsen, M; Woestenborghs, R, 1992) |
"The rate of success in treating onychomycosis with 40% urea ointment containing 1% bifonazole, with and without oral griseofulvin, was evaluated." | ( Bergman, R; Cohen, A; Friedman-Birnbaum, R; Shemer, A, 1992) |
"The good effect of this solution in the treatment of onychomycosis is in correlation with a good in vitro activity with MICs of 5% against Tr." | ( Faergemann, J; Swanbeck, G, 1989) |
"The difficulties encountered in the treatment of onychomycosis are primarily related to the necessity of prolonged systemic therapy." | ( De Simone, C; Ruffilli, MP; Tulli, A, 1988) |
"We have treated 48 cases of onychomycosis (of which 37 were caused by dermatophytes, 10 by yeasts and one by Scopulariopsis brevicaulis) with 200 mg ketoconazole daily." | ( Achten, G; André, J; Parent, D; Wiame, L, 1984) |
"In our investigations into the treatment of onychomycosis we studied the use of bifonazole (1%)-urea ointment and the therapeutic possibilities in connection with its application." | ( Nolting, S, 1984) |
"Current treatment of onychomycosis of the toenail is poor and relapse is common." | ( Ellis, D; Marley, J; Watson, A; Williams, T, 1995) |
"In the treatment of onychomycosis, oral therapies have generally been given as a continuous-dosing regimen." | ( De Doncker, P; Decroix, J; Dockx, P; Heremans, A; Jacqmin, P; Odds, F; Piérard, GE; Roelant, D; Roseeuw, D; Woestenborghs, R, 1996) |
"Until recently, the treatment of onychomycosis was discouraging because of the relatively low success rate, the need for prolonged therapy, and the laboratory monitoring necessary with the traditional oral antifungal agents, griseofulvin and ketoconazole." | ( Odom, RB, 1996) |
"The efficacy of terbinafine in the treatment of onychomycosis and other dermatomycoses is reviewed." | ( Gupta, AK; Shear, NH, 1997) |
"These results suggest that the topical treatment of onychomycosis by occlusive dressing is a useful method for those patients who have difficulties in or do not wish to be treated with oral antifungal agents." | ( Higashi, N; Kasai, T; Kitamura, K; Komatsuzaki, H; Nakashima, Y; Nishimoto, K; Ogawa, H; Oka, K; Takiuchi, I; Tsuboi, R; Unno, K, 1998) |
"Terbinafine is used extensively to treat onychomycosis and other dermatomycoses." | ( Gupta, AK; Porges, AJ, 1998) |
"The usual short-term treatment of onychomycosis over 3 months can be insufficient in individual cases such as patients with disorders, e." | ( Seebacher, C, 1998) |
"In addition to the importance of treating onychomycosis in the general population, there is strong clinical impetus to treat patients with concomitant conditions in order to prevent primary disease-related complications that, ultimately, can be life-threatening." | ( Albreski, DA; Gross, EG; Gupta, AK, 1999) |
"Modern treatments for onychomycosis do not yield an ideal cure rate." | ( Arrese, JE; Piérard, GE; Piérard-Franchimont, C, 2000) |
"The 2 most common agents used to treat dermatophyte onychomycosis of the toe are terbinafine (continuous) and itraconazole (pulse)." | ( Gupta, AK; Konnikov, N; Lynde, CW, 2001) |
"In the treatment of onychomycosis, continuous terbinafine provided superior long-term mycological and clinical efficacy and lower rates of mycological and clinical relapse compared with intermittent itraconazole." | ( Billstein, S; Evans, EG; Olafsson, JH; Paul, C; Sigurgeirsson, B; Steinsson, JB, 2002) |
"These results suggest that the initial treatment for onychomycosis should be a 4-month continuous course of terbinafine." | ( Heikkilä, H; Stubb, S, 2002) |
"Further studies are required on the treatment of onychomycosis with nail lacquers." | ( Baran, R; Gupta, AK; Ryder, JE, 2003) |
"Successful treatment of onychomycosis in the infection site depends not only on achieving the minimal inhibitory concentration (MIC) of the antifungal agent, usually determined on fresh, proliferating fungal strains, but also on the effectivity against fungal spores dormant in nail keratin." | ( Seebacher, C, 2003) |
"The successful treatment of onychomycosis requires special knowledge of the various clinical presentations, of the differential diagnosis and of recent advances in medical mycology." | ( Reinel, D, 2004) |
"Topical treatment of onychomycosis, as opposed to oral therapies, offers a distinct advantage by allowing the patient to apply medication directly to the affected area, thus decreasing the potential for serious adverse events, such as drug toxicity and drug interactions." | ( Albert, SF; Weis, ZH, 2004) |
"An alternative approach to treat onychomycosis may possibly be the application of a biological control agent against the pathogen." | ( Dror, Y; Freeman, A; Omero, C, 2004) |
"For the treatment of onychomycosis, ravuconazole 200 mg/day for 12 weeks is the most effective of the regimens investigated." | ( Conetta, B; Gupta, AK; Leonardi, C; Pierce, PF; Stoltz, RR, 2005) |
"Itraconazole may be effective in the treatment of onychomycosis caused by F." | ( Hattori, N; Li, W; Misawa, Y; Okuzumi, K; Shirai, A; Sugiura, Y; Tamaki, K; Yokoyama, K, 2005) |
"Effective treatments for onychomycosis are expensive." | ( Bloomfield, HE; Carver, SM; Fett, DD; Grill, JP; Lederle, FA; Nelson, DB; Quintero, V; Warshaw, EM; Zielke, GR, 2005) |
"When treating onychomycosis with oral itraconazole, the results seemed to be just as safe as when using terbinafine." | ( Dai, XY; Hu, Y; Hua, HK; Qi, J; Sun, H; Wei, L; Yang, LJ; Zheng, Y, 2005) |
"Systemic treatment of onychomycosis is based these last years on the new drug utilization aiming to decrease the length of the treatment and secondary effects particularly with fluconazole." | ( Ben Osman Dhahril, A; Bouassida, S; Denguezli, M; Doss, N; El Euch, D; Ezzine, N; Kourda, M; Mokhtar, I; Nouira, R; Ridha Kamoun, M; Turki, H, 2006) |
"The difficulty in treating onychomycosis results from the deep-seated nature of the infection within the nail unit (nail plate, nail bed and surrounding tissue) and the inability of drugs to effectively reach all sites." | ( Alley, MR; Baker, SJ; Beutner, KR; Plattner, J, 2007) |
"Terbinafine, indicated for the treatment of onychomycosis and ringworm, may rarely be associated with granulocytopenia, which is typically severe." | ( Boyd, IW; Pillans, PI, 2007) |
"Itraconazole is widely used to treat onychomycosis because of its significant therapeutic effects." | ( Fukunami, M; Kioka, H; Okamoto, J, 2007) |
"Before treating onychomycosis, it is important to exclude other conditions such as lichen planus and psoriasis." | ( Finnegan, MT; Koshnick, RL; Lilly, KK; St Clair, K; Warshaw, EM, 2007) |
"Itraconazole, while an effective treatment for onychomycosis, is not a first-choice therapy due to its black-box cardiac warning and numerous drug interactions." | ( Cantrell, W; Cathcart, S; Elewski, Be, 2009) |
"In the treatment of onychomycosis, compliance and drug interactions are important considerations, as diabetic patients frequently take concomitant medications." | ( Budihardja, D; Freund, V; Mayser, P, 2009) |
"The response to treatment of onychomycosis with itraconazole in psoriasis patients was found to be lower than in the general population." | ( Amichai, B; Davidovici, B; Grunwald, MH; Shemer, A; Trau, H, 2010) |
"Seven studies evaluating fluconazole treatment for onychomycosis were identified." | ( Brown, SJ, 2009) |
"Standard treatment for onychomycosis often results in less than half of subjects achieving disease-free nails." | ( Kerrouche, N; Olafsson, JH; Sidou, F; Sigurgeirsson, B; Steinsson, JT, 2010) |
"A case of untreated fusarial onychomycosis leading to serious consequences is reported." | ( Chen, GS; Lan, CC; Wu, CY, 2009) |
"Existing treatments of onychomycosis are not satisfactory." | ( Betz, G; Huonder, C; Vejnovic, I, 2010) |
"These results indicated topical treatment of onychomycosis with a combination of fluconazole 1% and urea 40% was more effective (82." | ( Bassiri-Jahromi, S; Ehsani, AH; Jamshidi, B; Mirshams-Shahshahani, M, 2012) |
"Therefore, the treatment of onychomycosis with griseofulvin seems futile." | ( de Silva, N; Ragunathan, RW; Ranawaka, RR, 2012) |
"Current topical treatments for onychomycosis are unsatisfactory." | ( Ghannoum, M; Sigurgeirsson, B, 2012) |
"Many treatment modalities for the treatment of onychomycosis have been studied, including topical lacquers and ointments, oral antifungals, surgical and chemical nail avulsion, and lasers." | ( Chacon, A; Franca, K; Ledon, JA; Nouri, K; Savas, J, 2014) |
"The successful treatment of onychomycosis depends on accurate diagnosis." | ( Chandran, NS; Pan, JY; Pramono, ZA; Seow, CS; Tan, HH, 2013) |
"Laser treatment of onychomycosis was not related to thermal damage or direct laser effects." | ( Cantrell, W; Carney, C; Elewski, B; Warner, J, 2013) |
"PACT appears to be an effective treatment of onychomycosis in vitro." | ( Borelli, C; Braunsdorf, C; Hahn, R; Köberle, M; Mailänder-Sanchez, D; Mehra, T; Röcken, M; Schaller, M; Schynowski, F; Walker, B, 2015) |
"for the topical treatment of onychomycosis of the toenail." | ( Markham, A, 2014) |
"Laser Treatment of onychomycosis is a quick and easy method without complications." | ( Galvan Garcia, HR, 2014) |
"Although oral and topical treatments for onychomycosis can potentially eradicate the infection, unsightly nails may remain despite negative mycology." | ( Gupta, AK; Paquet, M, 2015) |
"Successful treatment of onychomycosis is both a clinical and therapeutic challenge." | ( Bhatia, N, 2015) |
"The systemic treatment of onychomycosis has been hampered by the reported side effects of antifungals in addition to the limited blood circulation to the affected nails." | ( Abd El Gawad, NA; Bseiso, EA; Nasr, M; Sammour, OA, 2016) |
"Efinaconazole is a safe and effective treatment for onychomycosis that can be used in a wide range of patients due to its broad-spectrum antifungal activity and low rate of treatment-related adverse events." | ( Cernea, M; Gupta, AK, 2016) |
"Tavaborole (5%) is FDA approved for treating toenail onychomycosis and has shown antifungal activities against yeast, moulds and dermatophytes." | ( Gupta, AK; Versteeg, SG, 2016) |
"Conventional treatments for onychomycosis include oral and topical antifungal agents." | ( Jeong, KH; Kim, TI; Lee, MH; Lee, SJ; Oh, IH; Shin, MK; Suh, DH, 2016) |
"The conventional treatment of onychomycosis, a common fungal infection, consists in the use of local and systemic drugs for 4-6 months." | ( Azevedo, RB; Gu, J; Jiang, CS; Longo, JPF; Morgado, LF; Muehlmann, LA; Narcizo, PS; Nunes, RB; Pereira, PAG; Py-Daniel, KR; Trávolo, ARF, 2017) |
"Topical antifungal treatments for onychomycosis are applied to clean, unpolished nails for 48 weeks or longer." | ( Brown, M; Foley, KA; Gupta, AK; Hall, S; Lowe, NG; Turner, R; Vlahovic, TC, 2018) |
"The topical-based treatment of onychomycosis remains a challenge because of the difficulty associated with penetrating the dense, protective structure of the keratinized nail plate." | ( Ghannoum, M; Gupta, AK; Markinson, B; Rock, F; Rycerz, A; Winter, T, 2018) |
"Photodynamic treatment of onychomycosis is considered a promising future therapy to overcome the frequent failure of currently used antifungals." | ( Däschlein, G; Gross, Z; Mahammed, A; Preuß, A; Röder, B; Saltsman, I; Shamali, N, 2018) |
"The conventional treatment of onychomycosis involves oral and topical therapy." | ( Dhamoon, RK; Gupta, M; Popli, H, 2019) |
"Many clinicians prefer to treat onychomycosis systemically." | ( Kuwano, Y; Sei, Y; Shimoyama, H, 2019) |
"Systemic treatment of onychomycosis presents safety issues due to possible drug-drug interactions and severe side effects." | ( Abdollahi, D; Afshar, M; Jafariazar, Z, 2020) |
"The main difficulties in the treatment of onychomycosis refer to the duration of treatments and their side effects." | ( Assunção, CB; Caligiorne, RB; de Figueiredo, SM; Johann, S; La Santrer, EFR; Rodrigues, AM; Soares de Abreu, AG, 2020) |
"This review covers currently available treatments for onychomycosis, with an emphasis on safety and tolerability." | ( Lipner, SR; Ricardo, JW, 2020) |