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propylene glycol and Onychomycosis

propylene glycol has been researched along with Onychomycosis in 3 studies

Propylene Glycol: A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
propane-1,2-diol : The simplest member of the class of propane-1,2-diols, consisting of propane in which a hydrogen at position 1 and a hydrogen at position 2 are substituted by hydroxy groups. A colourless, viscous, hygroscopic, low-melting (-59degreeC) and high-boiling (188degreeC) liquid with low toxicity, it is used as a solvent, emulsifying agent, and antifreeze.

Onychomycosis: A fungal infection of the nail, usually caused by DERMATOPHYTES; YEASTS; or nondermatophyte MOLDS.

Research Excerpts

ExcerptRelevanceReference
"Onychomycosis is difficult to cure as this requires eradication of the primary infection and protection of new areas of growth from reinfection."6.77Treatment of distal subungual onychomycosis with a topical preparation of urea, propylene glycol and lactic acid: results of a 24-week, double-blind, placebo-controlled study. ( Emtestam, L; Kaaman, T; Rensfeldt, K, 2012)
" In this study, to improve the toenail delivery of efinaconazole (EFN), a triazole derivative for onychomycosis treatment, topical solutions containing different penetration enhancers were designed, and the permeation profiles were evaluated using bovine hoof models."4.02Effect of Penetration Enhancers on Toenail Delivery of Efinaconazole from Hydroalcoholic Preparations. ( Choi, YS; Ho, MJ; Jang, SW; Kang, MJ; Kim, EA; Kim, JS; Park, DW; Park, JS, 2021)
"Onychomycosis is difficult to cure as this requires eradication of the primary infection and protection of new areas of growth from reinfection."2.77Treatment of distal subungual onychomycosis with a topical preparation of urea, propylene glycol and lactic acid: results of a 24-week, double-blind, placebo-controlled study. ( Emtestam, L; Kaaman, T; Rensfeldt, K, 2012)
"Onychomycosis is a challenging fungal infection to treat topically, likely due to the unique properties of the nail plate."1.34In Vitro penetration of a novel oxaborole antifungal (AN2690) into the human nail plate. ( Akama, T; Baker, SJ; Barbadillo, S; Cashmore, AK; Hold, KM; Hui, X; Maibach, HI; Plattner, JJ; Sanders, V; Wester, RC; Zhang, YK, 2007)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Park, JS1
Kim, JS1
Ho, MJ1
Park, DW1
Kim, EA1
Choi, YS1
Jang, SW1
Kang, MJ1
Emtestam, L1
Kaaman, T1
Rensfeldt, K1
Hui, X1
Baker, SJ1
Wester, RC1
Barbadillo, S1
Cashmore, AK1
Sanders, V1
Hold, KM1
Akama, T1
Zhang, YK1
Plattner, JJ1
Maibach, HI1

Trials

1 trial available for propylene glycol and Onychomycosis

ArticleYear
Treatment of distal subungual onychomycosis with a topical preparation of urea, propylene glycol and lactic acid: results of a 24-week, double-blind, placebo-controlled study.
    Mycoses, 2012, Volume: 55, Issue:6

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifungal Agents; Double-Blind Method; Dru

2012

Other Studies

2 other studies available for propylene glycol and Onychomycosis

ArticleYear
Effect of Penetration Enhancers on Toenail Delivery of Efinaconazole from Hydroalcoholic Preparations.
    Molecules (Basel, Switzerland), 2021, Mar-16, Volume: 26, Issue:6

    Topics: Administration, Topical; Animals; Antifungal Agents; Cattle; Diffusion; Drug Carriers; Drug Delivery

2021
In Vitro penetration of a novel oxaborole antifungal (AN2690) into the human nail plate.
    Journal of pharmaceutical sciences, 2007, Volume: 96, Issue:10

    Topics: Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chemistry, Pharmaceutic

2007