Page last updated: 2024-09-27

Polymyositis

Diseases characterized by inflammation involving multiple muscles. This may occur as an acute or chronic condition associated with medication toxicity (DRUG TOXICITY); CONNECTIVE TISSUE DISEASES; infections; malignant NEOPLASMS; and other disorders. The term polymyositis is frequently used to refer to a specific clinical entity characterized by subacute or slowly progressing symmetrical weakness primarily affecting the proximal limb and trunk muscles. The illness may occur at any age, but is most frequent in the fourth to sixth decade of life. Weakness of pharyngeal and laryngeal muscles, interstitial lung disease, and inflammation of the myocardium may also occur. Muscle biopsy reveals widespread destruction of segments of muscle fibers and an inflammatory cellular response. (Adams et al., Principles of Neurology, 6th ed, pp1404-9)

Synonyms(1)

Synonym
Polymyositis

Research Excerpts

Overview

ExcerptReference
"Polymyositis is a rarely reported complication of chronic graft-versus-host disease (GVHD) with only 8 cases described in the literature."( Ben-Ezra, J; Blume, KG; Chao, NJ; Forman, SJ; Greffe, BS; Kashyap, A; Linker, CA; Molina, A; Nademanee, A; Niland, JC; O'Donnell, MR; Openshaw, H; Parker, P; Planas, I; Sheibani, K; Slatkin, N; Smith, EP; Snyder, DS; Spielberger, R; Stein, AS; Stepan, DE, 1996)
"Both alopecia and polymyositis are rarely associated with inflammatory bowel disease; thus, they have to be discussed as extraintestinal manifestations."( Jakob, F; Klein, R; Seibold, F, 1996)
"Polymyositis is an inflammatory muscle disease with unknown cause that is characterized by progressive weakness of the proximal muscles."( Dobashi, H; Hiraishi, T; Mitsunaka, H; Takahara, J; Tokuda, M, 2000)
"Polymyositis is a rare autoimmune manifestation of chronic graft-versus-host disease (GVHD) characterized by muscle pain, weakness, and an increase in muscle-related enzymes that responds well to treatment with immunosuppressive agents such as steroids and cyclosporine."( Chandy, M; Danda, D; George, B; Mathews, V; Srivastava, A, 2001)
"When a case of polymyositis is superimposed with pulmonary tuberculosis, it should be remembered that RFP may shorten the half-life of any steroid or CyA that is administered as treatment."( Hayashi, R; Kawasaki, A; Kobayashi, M; Maruyama, M; Shinoda, C, 2001)
"Dermatomyositis and polymyositis are the two major idiopathic inflammatory myopathies."( Hachulla, E, 2001)
"Polymyositis is a rare manifestation of cGvHD in adult patients following allogeneic BMT."( Duffner, U; Ehl, S; Franck, P; Klein, R; Niemeyer, CM; Schmitt-Graeff, A, 2007)
"Polymyositis is a rare collagen disease that can involve the lungs."( Casanova, A; García, A; Girón, RM; Hoyos, N; Sánchez, S; Valenzuela, C, 2007)
"Polymyositis is an uncommon manifestation as a complication of chronic graft-versus-host disease (GVHD)."( Inoue, M; Kitazono, T; Maeda, A; Okazaki, T; Ozaki, S; Shibata, T, 2009)
"Polymyositis is a rare manifestation of chronic GVHD after donor lymphocyte infusion (DLI)."( Ahn, JS; Bae, WK; Cho, SH; Chung, IJ; Juhng, SW; Kim, HJ; Kim, YK; Lee, JJ; Shim, HJ; Yang, DH, 2009)
"Polymyositis is an inflammatory myopathy which, like SCD, may present with myalgia but is usually associated with proximal muscle weakness."( Bali, S; D'Cruz, D; Inusa, BP; Lazaro, M, 2015)
"The treatment of polymyositis is based on corticosteroid therapy, with addition of azathioprine for non responsive cases or as an attempt to diminish corticosteroids requirements."( Meneses, C; Rada, G, 2015)
"Dermatomyositis and polymyositis are rare chronic inflammatory disorders with significant associated morbidity and mortality despite treatment."( McHugh, NJ; Tansley, SL; Vermaak, E, 2015)
"Polymyositis is a rare medical disorder complicating pregnancy."( Ali, HS; Fadlelmula, AE; George, S; Hassan, IF, 2017)
"Polymyositis is an idiopathic inflammatory myopathy, characterized by proximal muscle weakness and sometimes extramuscular manifestations."( Bettencourt, P; Carneiro-Leão, L; Morais, R; Pinheiro, J; Pinto-Lopes, P; Vieira Lopes, A, 2017)
"Polymyositis is a rare neuromuscular manifestation of GVHD, which often responds well to corticosteroid and immunosuppression therapy."( Bal, A; Khadwal, AR; Kumar, R; Lukose, T; Mittal, BR; Singh, H; Sood, A, 2020)
"Polymyositis is an inflammatory myopathy, and its cardiac involvement seldom presents as myopericarditis and anti-Ku positive."( Dong, B; Gu, J; Peng, Y; Tan, W; Xue, R, 2021)
"Polymyositis is rarely associated with Graves' disease."( Achok, HN; Chai, ST; Lim, YS, 2021)
"Polymyositis is an immune-mediated inflammatory myopathy usually presenting with weakness of proximal muscles in a symmetric pattern."( Chandra, A; Ghosh, SK; Karmakar, P; Karmakar, PS; Ray, AK, 2022)

Treatment

ExcerptReference
"To describe the treatment of polymyositis (PM) and dermatomyositis (DM) with prednisone (PRED) and cyclosporin A (CSA) alone or associated with intravenous immunoglobulin (IVIg) and plasmapheresis (PEX)."( Danieli, G; Danieli, MG; Logullo, F; Malcangi, G; Palmieri, C; Piani, M; Salvi, A, 2002)
"In the treatment of polymyositis (PM) and dermatomyositis (DM), muscle inflammation and underlying autoimmunity need to be suppressed promptly; however, catabolic effects of corticosteroids such as myopathy can be detrimental in PM/DM."( Furuta, S; Hirose, K; Ikeda, K; Nakajima, H; Yokoyama, Y, 2015)

Research

Studies (547)

TimeframeStudies, This Condition (%)All Conditions %
pre-199030 (5.48)23.3326
1990's152 (27.79)12.5806
2000's182 (33.27)18.1394
2010's147 (26.87)28.8240
2020's36 (6.58)9.53
DrugIndicatedRelationship StrengthStudiesTrials
quinacrine0low10
betaine0low10
carnitine0low10
choline0low10
citric acid, anhydrous0low10
creatine0low40
glycerol0low10
phytic acid0low10
niacin0low10
nitrites0low10
uric acid0low30
albendazole0low10
alendronate0low10
amiodarone0low10
aspirin0low40
azathioprine0medium511
baclofen0low10
chlorambucil0low10
chloroquine0low10
citalopram0low10
diclofenac0low10
diethylcarbamazine0low10
pentetic acid0low20
valproic acid0low10
erythrosine0low10
etidronate0low10
fenofibrate0low30
fluconazole0low10
fluorouracil0low10
furosemide0low10
gemfibrozil0low20
hydroxychloroquine0low30
isoniazid0low10
lansoprazole0low10
leflunomide0low30
mesalamine0low10
metronidazole0low10
mexiletine0low10
neostigmine0low20
omeprazole0low40
pantoprazole0low10
pyrimethamine0low20
rabeprazole0low10
sulfadiazine0low20
tiopronin0low30
troglitazone0low10
corticosterone0low10
prednisolone0medium942
hydroxyproline0low10
thyroxine0low30
spironolactone0low10
aldosterone0low10
penicillamine0low60
aspartic acid0low10
lysine0low10
adenosine diphosphate0medium11
tyrosine0low10
methionine0low10
colchicine0low20
tryptophan0low10
arginine0low10
vinyl chloride0low10
methylprednisolone0medium371
pyrroles0low30
diatrizoate meglumine0low10
quinazolines0low10
isoxazoles0low30
thiazoles0low10
citrulline0low20
nandrolone0low10
acetylcysteine0low10
deoxycytidine0low10
ethambutol0low20
dicloxacillin0low10
fluorescein-5-isothiocyanate0low20
sabinene0low10
vidarabine0medium11
iodinated glycerol0low10
technetium0low10
trolamine salicylate0low310
fluorides0low10
ursodeoxycholic acid0low20
glutamic acid0low10
gallium citrate0low10
zidovudine0low30
etoposide0low10
bezafibrate0low10
diltiazem0low10
pefloxacin0low10
lovastatin0low10
simvastatin0low30
pravastatin0low20
gemcitabine0low10
atorvastatin0low40
vanadates0low10
fluorophosphate0low10
cephalosporin c0low10
xenon radioisotopes0low10
fluorodeoxyglucose f180low140
clarithromycin0low10
fibrinogen0low10
mizoribine0low10
n(6)-carboxymethyllysine0low10
methotrexate0medium574
febuxostat0low10
ezetimibe0low10
pentigide0low10
erlotinib hydrochloride0low10
cortisone0low60
3-nitrotyrosine0low10
2'-fluorothymidine0low10
trimethoprim, sulfamethoxazole drug combination0low20
calcein am0low10
fibrin0low10
epiglucan0low20
laminaran0low10
pentostatin0low10
inositol 3-phosphate0low10
meropenem0low10
pentazocine0low10
pancuronium0low10
rocuronium0low10
palmitoleic acid0low10
tacrolimus0medium302
mycophenolic acid0low210
zithromax0low10
riboflavin0low10
bromochloroacetic acid0low10
buprenorphine0low10
bucillamine0low10
fludarabine0medium11
mercaptopurine0low10
methimazole0low10
ranitidine0low10
2-fluoro-2-deoxyglucose-6-phosphate0low10
bilirubin0low20
calcitriol0low10
alprostadil0low20
5-hydroxy-6,8,11,14-eicosatetraenoic acid0low10
stigmasterol0low10
cholecalciferol0low10
coenzyme q100low10
sirolimus0low20
desonide0low10
gallium0low10
cysteine0low10
phosphorus0low30
trandolapril0low10
cefotaxime0low10
emerin0low10
axitinib0medium11
technetium tc 99m pyrophosphate0low20
ca 074 methyl ester0low10
gadolinium dtpa0low20
staurosporine0low10
phosphocreatine0medium31
s 17430low10
mocetinostat0low30
tofacitinib0low30
dimethylarginine0low10
alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-D-GlcpNAc0low10
arabinofuranosyluracil0low10
c-peptide0low10
cellulose0low10
endothelin-10low10
ubiquinone0low10
calpain0low20
florbetapir f 180low20
pervanadate0low10
baricitinib0low10
piperidines0low30
interleukin-80low30
natriuretic peptide, brain0low30
minocycline0low20
salicylates0low10
transforming growth factor beta0low80
cyclosporine0medium431
lactoferrin0low10
technetium tc 99m medronate0low70
exudates0low20
entecavir0low10
levoleucovorin0low20
guanine0low10
folic acid0low10
neopterin0low20
rifampin0low10
didanosine0low10

Protein Targets (1,876)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Putative fructose-1,6-bisphosphate aldolase120012
Chain A, JmjC domain-containing histone demethylation protein 3A120012
phosphopantetheinyl transferase280028
bromodomain adjacent to zinc finger domain 2B130013
euchromatic histone-lysine N-methyltransferase 2470047
pyruvate kinase PKM isoform a3003
geminin480048
Glycoprotein hormones alpha chain1001
Guanine nucleotide-binding protein G4004
Tubulin--tyrosine ligase0202
Microtubule-associated protein tau200020
Polyunsaturated fatty acid 5-lipoxygenase0101
Inositol monophosphatase 16006
Chain A, 2-oxoglutarate Oxygenase170017
Chain A, ATP-DEPENDENT DNA HELICASE Q15005
acetylcholinesterase200020
dopamine D1 receptor4004
15-lipoxygenase, partial100010
pregnane X receptor110011
RAR-related orphan receptor gamma460046
USP1 protein, partial230023
NFKB1 protein, partial9009
Thrombopoietin100010
AR protein640064
regulator of G-protein signaling 4150015
glucocorticoid receptor [Homo sapiens]420042
retinoic acid nuclear receptor alpha variant 1500050
retinoid X nuclear receptor alpha420042
farnesoid X nuclear receptor330033
estrogen nuclear receptor alpha740074
vitamin D (1,25- dihydroxyvitamin D3) receptor360036
arylsulfatase A150015
Bloom syndrome protein isoform 1150015
D(1A) dopamine receptor9009
thyroid hormone receptor beta isoform a200020
thyroid hormone receptor beta isoform 2460046
heat shock protein beta-1210021
flap endonuclease 1130013
peripheral myelin protein 22240024
survival motor neuron protein isoform d260026
muscarinic acetylcholine receptor M1170017
Histone deacetylase 30606
Solute carrier family 22 member 60506
Histone deacetylase 40505
Histone deacetylase 10808
Histone deacetylase 70505
Histone deacetylase 20808
Polyamine deacetylase HDAC100404
Histone deacetylase 11 0505
Ataxin-2310031
Histone deacetylase 80505
Histone deacetylase 60707
Histone deacetylase 90404
Histone deacetylase 50505
ATP-dependent phosphofructokinase230023
Chain A, Heat Shock Protein 900011
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, Myosin Ie Heavy Chain0011
Chain A, Preprotein translocase secA0011
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Phosphoribosylformylglycinamidine synthase0101
Chain A, nucleoside diphosphate kinase A0011
Chain B, nucleoside diphosphate kinase A0011
Chain D, DNA polymerase III subunit gamma0011
Chain D, DNA polymerase III subunit gamma0011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A, Kinesin-like protein KIF110101
HPr kinase/phosphorylase0011
Mitogen-activated protein kinase kinase kinase 70033
ATP-dependent molecular chaperone HSP820001
Heat shock protein HSP 90-alpha0113
Heat shock protein HSP 90-beta0113
2-dehydropantoate 2-reductase0112
Heat shock 70 kDa protein 1A 0112
Endoplasmic reticulum chaperone BiP0011
Heat shock cognate 71 kDa protein0011
Pyruvate kinase PKM 0001
Pyruvate kinase PKLR 0001
Endoplasmin0001
Heat shock cognate 71 kDa protein0011
5'-nucleotidase0101
Mu-type opioid receptor0314
Delta-type opioid receptor0213
Kappa-type opioid receptor0415
Endoplasmin0112
P2Y purinoceptor 20011
Phosphatidylinositol 4-kinase alpha0202
P2X purinoceptor 10011
P2Y purinoceptor 10011
P2Y purinoceptor 10011
P2X purinoceptor 10011
P2X purinoceptor 40011
P2X purinoceptor 50011
P2X purinoceptor 60011
P2X purinoceptor 30011
Heat shock protein 75 kDa, mitochondrial0101
P2Y purinoceptor 60011
Phosphatidylinositol 4-kinase type 2-beta0202
P2Y purinoceptor 110011
Phosphatidylinositol 4-kinase type 2-alpha0202
P2Y purinoceptor 120112
Sensor protein kinase WalK0101
Phosphatidylinositol 4-kinase beta0224
P2X purinoceptor 20011
Chain A, Beta-lactamase110011
Luciferase250025
glp-1 receptor, partial130013
hypoxia-inducible factor 1 alpha subunit170017
ATAD5 protein, partial140014
Fumarate hydratase120012
TDP1 protein550055
GLI family zinc finger 3500050
caspase 7, apoptosis-related cysteine protease9009
nuclear receptor subfamily 1, group I, member 3370037
progesterone receptor320032
estrogen-related nuclear receptor alpha520052
pregnane X nuclear receptor430043
polyprotein120012
67.9K protein160016
peroxisome proliferator activated receptor gamma360036
caspase-39009
IDH1190019
aryl hydrocarbon receptor270027
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a340034
v-jun sarcoma virus 17 oncogene homolog (avian)280028
nuclear receptor subfamily 1, group I, member 2110011
Histone H2A.x220022
cellular tumor antigen p53 isoform a100010
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1140014
chromobox protein homolog 1280028
nuclear factor erythroid 2-related factor 2 isoform 2190019
transcriptional regulator ERG isoform 35005
histone deacetylase 9 isoform 35005
mitogen-activated protein kinase 1100010
urokinase-type plasminogen activator precursor160016
plasminogen precursor160016
urokinase plasminogen activator surface receptor precursor160016
Vif0001
muscleblind-like protein 1 isoform 1110011
DNA dC->dU-editing enzyme APOBEC-3G isoform 12002
lamin isoform A-delta10390039
neuropeptide S receptor isoform A5005
ATP-binding cassette sub-family C member 3051051
Multidrug resistance-associated protein 4051054
Voltage-dependent calcium channel gamma-2 subunit270027
Bile salt export pump069069
Interferon beta350035
Cellular tumor antigen p53420042
Integrin beta-381110
Integrin alpha-IIb81110
Methionine aminopeptidase0101
Glutamate receptor 2273131
Fatty-acid amide hydrolase 10202
Canalicular multispecific organic anion transporter 1048049
ATPase family AAA domain-containing protein 5230023
Sex hormone-binding globulin0044
Corticosteroid-binding globulin0505
Mineralocorticoid receptor 05410
Androgen receptor013014
Mineralocorticoid receptor0101
Solute carrier organic anion transporter family member 1A10204
Chain A, farnesyl pyrophosphate synthase0101
Geranylgeranyl pyrophosphate synthase0101
Farnesyl pyrophosphate synthase0202
Acetylcholinesterase0707
Hypoxanthine-guanine phosphoribosyltransferase0101
Farnesyl pyrophosphate synthase 0101
Farnesyl pyrophosphate synthase 0101
Thromboxane-A synthase 0303
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP1 subtype0101
Prostacyclin receptor0112
Nuclear receptor subfamily 4 group A member 20033
Solute carrier organic anion transporter family member 2A10102
Nuclear receptor subfamily 4 group A member 20011
Nuclear receptor subfamily 4 group A member 20011
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier organic anion transporter family member 2A10001
Solute carrier organic anion transporter family member 2B10101
Solute carrier organic anion transporter family member 3A10001
Chain A, TYROSYL-DNA PHOSPHODIESTERASE220022
SMAD family member 2190019
PPM1D protein110011
SMAD family member 3190019
aldehyde dehydrogenase 1 family, member A1360036
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)130013
thyroid stimulating hormone receptor220022
estrogen receptor 2 (ER beta)270027
EWS/FLI fusion protein320032
G240024
cytochrome P450 2D6240024
peroxisome proliferator-activated receptor delta340034
thyroid stimulating hormone receptor190019
cytochrome P450 2D6 isoform 17007
cytochrome P450 2C9 precursor8008
potassium voltage-gated channel subfamily H member 2 isoform d130013
huntingtin isoform 27007
serine/threonine-protein kinase mTOR isoform 18008
nuclear factor erythroid 2-related factor 2 isoform 1500050
peptidyl-prolyl cis-trans isomerase NIMA-interacting 18008
nuclear receptor ROR-gamma isoform 1180018
cytochrome P450 3A4 isoform 1240024
lethal factor (plasmid)8008
Gamma-aminobutyric acid receptor subunit pi240024
Polyunsaturated fatty acid lipoxygenase ALOX15B8008
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Solute carrier organic anion transporter family member 1A40204
Voltage-dependent L-type calcium channel subunit alpha-1F0808
5-hydroxytryptamine receptor 4012315
Lysine-specific demethylase PHF20101
HLA class I histocompatibility antigen, B alpha chain 240024
Thyroid hormone receptor alpha0101
Receptor tyrosine-protein kinase erbB-20325
Tyrosine-protein kinase Fyn0145
ATP-dependent translocase ABCB10404
Aldo-keto reductase family 1 member B1015015
Muscarinic acetylcholine receptor M2011012
Muscarinic acetylcholine receptor M40809
ATP-dependent translocase ABCB1017221
Beta-1 adrenergic receptor0303
Muscarinic acetylcholine receptor M50809
Alpha-2A adrenergic receptor0808
Adenosine receptor A3011011
Cytochrome P450 2C80404
Thyroid hormone receptor alpha0112
Thyroid hormone receptor beta0112
Muscarinic acetylcholine receptor M10809
Beta-3 adrenergic receptor0505
D(2) dopamine receptor0404
Gamma-aminobutyric acid receptor subunit beta-1240024
Alpha-1B adrenergic receptor011011
Lethal factor0101
Alpha-2B adrenergic receptor012012
Thyroid hormone receptor beta0101
Gamma-aminobutyric acid receptor subunit delta240024
Gamma-aminobutyric acid receptor subunit gamma-2240125
Gamma-aminobutyric acid receptor subunit alpha-5240024
Gamma-aminobutyric acid receptor subunit alpha-3240024
Muscarinic acetylcholine receptor M30809
ATP-dependent translocase ABCB10404
Substance-K receptor0404
D(1A) dopamine receptor0303
D(4) dopamine receptor0202
Gamma-aminobutyric acid receptor subunit gamma-1240024
Gamma-aminobutyric acid receptor subunit alpha-2240024
Carnitine O-palmitoyltransferase 2, mitochondrial0101
Sodium-dependent noradrenaline transporter 014014
Histamine H2 receptor0404
Endothelin-1 receptor0505
5-hydroxytryptamine receptor 2A010010
5-hydroxytryptamine receptor 2C012012
Gamma-aminobutyric acid receptor subunit alpha-4240024
Gamma-aminobutyric acid receptor subunit gamma-3240024
Lysine-specific demethylase 5A0101
Gamma-aminobutyric acid receptor subunit alpha-6240024
B2 bradykinin receptor0202
Sodium-dependent serotonin transporter0617
Melanocortin receptor 40202
C-8 sterol isomerase0202
Melanocortin receptor 50202
D(3) dopamine receptor010010
Sodium channel protein type 1 subunit alpha0404
Sodium channel protein type 4 subunit alpha0404
Squalene synthase0101
5-hydroxytryptamine receptor 2B012012
C-C chemokine receptor type 20404
Melanocortin receptor 30202
Alpha-1A adrenergic receptor011011
Histamine H2 receptor130014
D(1A) dopamine receptor2002
5-hydroxytryptamine receptor 60202
Carnitine O-palmitoyltransferase 1, liver isoform0101
C-C chemokine receptor type 40202
Spike glycoprotein251430
Gamma-aminobutyric acid receptor subunit alpha-1241126
Gamma-aminobutyric acid receptor subunit beta-3240024
Gamma-aminobutyric acid receptor subunit beta-2240125
Sodium channel protein type 7 subunit alpha0404
Voltage-dependent L-type calcium channel subunit alpha-1D 0808
Sodium-dependent dopamine transporter 0909
Potassium voltage-gated channel subfamily H member 2015015
Voltage-dependent L-type calcium channel subunit alpha-1S0808
Voltage-dependent L-type calcium channel subunit alpha-1C0809
Sodium channel protein type 5 subunit alpha0606
Squalene monooxygenase0101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0202
Sodium channel protein type 9 subunit alpha0505
Lysine-specific demethylase 7A0101
GABA theta subunit240024
Carnitine O-palmitoyltransferase 1, muscle isoform0101
Inositol hexakisphosphate kinase 1240024
Sodium channel protein type 2 subunit alpha0404
Sigma non-opioid intracellular receptor 1012113
Gamma-aminobutyric acid receptor subunit epsilon240024
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0011
Sodium channel protein type 3 subunit alpha0404
Sodium channel protein type 11 subunit alpha0404
Histone lysine demethylase PHF80101
Sodium channel protein type 8 subunit alpha0404
Sodium channel protein type 10 subunit alpha0404
cytochrome P450 2C9, partial240024
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE180018
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
thioredoxin reductase260026
GLS protein180018
alpha-galactosidase5005
cytochrome P450 2C19 precursor110011
DNA polymerase iota isoform a (long)150015
Cytochrome P450 3A4020023
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0102
Nitric oxide synthase, brain 0102
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30202
Chain A, Ferritin light chain110011
Metabotropic glutamate receptor 60124
Excitatory amino acid transporter 40202
Glutamate transporter homolog0011
Carbonic anhydrase 109014
Carbonic anhydrase 2010116
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
5-hydroxytryptamine receptor 1D0001
Glutamate receptor ionotropic, NMDA 1 0317
Excitatory amino acid transporter 10304
Excitatory amino acid transporter 20304
Excitatory amino acid transporter 30304
Glutamate receptor ionotropic, NMDA 2A 0317
Glutamate receptor ionotropic, NMDA 2B0418
Glutamate receptor ionotropic, NMDA 2C0317
Metabotropic glutamate receptor 10124
Metabotropic glutamate receptor 20124
Carbonic anhydrase-like protein, putative0004
Glutamate receptor ionotropic, NMDA 2D0317
Glutamate receptor ionotropic, NMDA 3B0317
Carbonic anhydrase 40102
Glutamate receptor ionotropic, NMDA 3A0317
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein160016
Chain B, HADH2 protein160016
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 8100010
hypothetical protein, conserved3003
cytochrome P450 family 3 subfamily A polypeptide 4370037
glucocerebrosidase5005
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
DNA polymerase kappa isoform 19009
Prostaglandin-H2 D-isomerase0101
Prostaglandin G/H synthase 1 0202
Prostaglandin G/H synthase 2 0101
Epidermal growth factor receptor0549
Fatty acid-binding protein, liver0617
Myeloperoxidase0303
Prostaglandin G/H synthase 10303
Seed linoleate 13S-lipoxygenase-10101
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10404
Adenosine receptor A10102
Adenosine receptor A2a0203
Substance-P receptor0202
Prostaglandin G/H synthase 2010212
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma140014
Ras-related protein Rab-2A0011
Prostaglandin G/H synthase 20202
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Sigma non-opioid intracellular receptor 10123
Chain A, Cruzipain6006
Caspase-72002
vitamin D3 receptor isoform VDRA190019
caspase-32002
Solute carrier organic anion transporter family member 2B1 0407
3-hydroxy-3-methylglutaryl-coenzyme A reductase0707
Insulin receptor 0505
Dipeptidyl peptidase 40101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0404
Solute carrier organic anion transporter family member 1B3012017
Broad substrate specificity ATP-binding cassette transporter ABCG2013014
Solute carrier organic anion transporter family member 1B1013019
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Leukotriene C4 synthase0022
tyrosine-protein kinase Yes3003
Bone morphogenetic protein receptor type-1B0044
Cell division cycle 7-related protein kinase0022
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform0022
Serine/threonine-protein kinase PLK40246
Serine/threonine-protein kinase 250022
ATP-dependent RNA helicase DDX3X0044
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta0022
Pyridoxal kinase0044
Citron Rho-interacting kinase0044
Serine/threonine-protein kinase RIO30022
Dual specificity mitogen-activated protein kinase kinase 70123
Serine/threonine-protein kinase Chk10145
Inhibitor of nuclear factor kappa-B kinase subunit beta0022
Peripheral plasma membrane protein CASK0022
Aurora kinase A0145
Cyclin-G-associated kinase0145
Serine/threonine-protein kinase DCLK10022
Inhibitor of nuclear factor kappa-B kinase subunit alpha0022
Muscle, skeletal receptor tyrosine-protein kinase0022
Ephrin type-B receptor 60044
Peroxisomal acyl-coenzyme A oxidase 30044
Mitogen-activated protein kinase 130123
3-phosphoinositide-dependent protein kinase 10022
Mitogen-activated protein kinase kinase kinase 130022
Death-associated protein kinase 30022
Receptor-interacting serine/threonine-protein kinase 20044
Mitotic checkpoint serine/threonine-protein kinase BUB10033
NUAK family SNF1-like kinase 10022
Dynamin-like 120 kDa protein, mitochondrial0044
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma0022
Tyrosine-protein kinase JAK204411
Eukaryotic translation initiation factor 5B0033
Rho-associated protein kinase 20145
Serine/threonine-protein kinase ULK10044
Serine/threonine-protein kinase/endoribonuclease IRE10044
Ribosomal protein S6 kinase alpha-50145
U5 small nuclear ribonucleoprotein 200 kDa helicase0044
Ribosomal protein S6 kinase alpha-40044
Serine/threonine-protein kinase 160044
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma0022
Serine/threonine-protein kinase PAK 30022
Cyclin-dependent kinase-like 50033
Serine/threonine-protein kinase 17B0022
Serine/threonine-protein kinase 100044
Serine/threonine-protein kinase D30044
Cyclin-dependent kinase 140022
Structural maintenance of chromosomes protein 20033
Mitogen-activated protein kinase kinase kinase 60044
Serine/threonine-protein kinase OSR10022
Mitogen-activated protein kinase kinase kinase kinase 40044
Serine/threonine-protein kinase LATS10044
Serine/threonine-protein kinase PAK 40044
Serine/threonine-protein kinase Chk20022
Tyrosine-protein kinase ABL10257
RAF proto-oncogene serine/threonine-protein kinase0022
High affinity nerve growth factor receptor0033
Guanine nucleotide-binding protein G(i) subunit alpha-20022
ADP/ATP translocase 20044
Protein kinase C beta type0145
Insulin receptor0145
Tyrosine-protein kinase Lck0145
Cyclin-dependent kinase 10044
Glycogen phosphorylase, liver form0044
Tyrosine-protein kinase Fes/Fps0044
Macrophage colony-stimulating factor 1 receptor0022
Adenine phosphoribosyltransferase0033
Tyrosine-protein kinase Yes0044
Tyrosine-protein kinase Lyn0044
Proto-oncogene tyrosine-protein kinase receptor Ret0044
Insulin-like growth factor 1 receptor0044
Signal recognition particle receptor subunit alpha0044
Cytochrome c1, heme protein, mitochondrial0044
Hepatocyte growth factor receptor0044
Tyrosine-protein kinase HCK0044
Proto-oncogene tyrosine-protein kinase ROS0022
Platelet-derived growth factor receptor beta0044
Tyrosine-protein kinase Fgr0033
Wee1-like protein kinase 20022
Uncharacterized serine/threonine-protein kinase SBK30022
Serine/threonine-protein kinase A-Raf0044
Cytochrome P450 2D60718
Mast/stem cell growth factor receptor Kit0123
Glycogen phosphorylase, brain form0044
Breakpoint cluster region protein0145
Serine/threonine-protein kinase pim-10145
Fibroblast growth factor receptor 10145
DNA topoisomerase 2-alpha01511
Cyclin-dependent kinase 40044
ADP/ATP translocase 30044
Inosine-5'-monophosphate dehydrogenase 20235
Proto-oncogene tyrosine-protein kinase Src0145
cAMP-dependent protein kinase type II-alpha regulatory subunit0033
Insulin receptor-related protein0022
Serine/threonine-protein kinase B-raf0044
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0044
Ribosyldihydronicotinamide dehydrogenase [quinone]0145
Platelet-derived growth factor receptor alpha0022
Tyrosine-protein kinase Fer0044
Protein kinase C alpha type0145
cAMP-dependent protein kinase catalytic subunit alpha0044
Vascular endothelial growth factor receptor 1 0123
General transcription and DNA repair factor IIH helicase subunit XPD0044
Interferon-induced, double-stranded RNA-activated protein kinase0022
Casein kinase II subunit alpha'0044
Ras-related protein Rab-6A0044
Serine/threonine-protein kinase MAK0022
Cyclin-dependent kinase 11B0022
Ephrin type-A receptor 10044
Fibroblast growth factor receptor 20022
Receptor tyrosine-protein kinase erbB-30022
Multifunctional protein ADE20044
Fibroblast growth factor receptor 40022
Fibroblast growth factor receptor 30022
cAMP-dependent protein kinase catalytic subunit gamma0033
cAMP-dependent protein kinase catalytic subunit beta0044
Ferrochelatase, mitochondrial0044
Ribosomal protein S6 kinase beta-10145
Tyrosine-protein kinase JAK104512
Protein kinase C eta type0022
Cyclin-dependent kinase 20156
Beta-adrenergic receptor kinase 10044
Probable ATP-dependent RNA helicase DDX60044
Activin receptor type-2A0022
Mitogen-activated protein kinase 3 0044
MAP/microtubule affinity-regulating kinase 30044
Deoxycytidine kinase0046
Mitogen-activated protein kinase 10145
Ephrin type-A receptor 20044
Ephrin type-A receptor 30022
Ephrin type-A receptor 80022
Ephrin type-B receptor 20044
Leukocyte tyrosine kinase receptor0022
Non-receptor tyrosine-protein kinase TYK204512
UMP-CMP kinase 0033
Phosphatidylethanolamine-binding protein 10033
Wee1-like protein kinase0044
Heme oxygenase 20044
Tyrosine-protein kinase receptor UFO0022
Mitogen-activated protein kinase 40022
S-adenosylmethionine synthase isoform type-20044
DnaJ homolog subfamily A member 10044
RAC-alpha serine/threonine-protein kinase0145
RAC-beta serine/threonine-protein kinase0044
G protein-coupled receptor kinase 40022
Dual specificity protein kinase TTK0033
DNA replication licensing factor MCM40033
Myosin-100033
Tyrosine-protein kinase receptor Tie-10022
Vascular endothelial growth factor receptor 30123
Vascular endothelial growth factor receptor 20224
Dual specificity mitogen-activated protein kinase kinase 20044
Receptor-type tyrosine-protein kinase FLT30044
Bone morphogenetic protein receptor type-1A0044
Activin receptor type-1B0044
TGF-beta receptor type-10044
Serine/threonine-protein kinase receptor R30044
TGF-beta receptor type-20044
Electron transfer flavoprotein subunit beta0033
Tyrosine-protein kinase CSK0145
Glycine--tRNA ligase0044
Protein kinase C iota type0044
Exosome RNA helicase MTR40044
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0123
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0022
Serine/threonine-protein kinase mTOR0336
Megakaryocyte-associated tyrosine-protein kinase0022
Tyrosine-protein kinase Tec0145
Tyrosine-protein kinase TXK0123
Tyrosine-protein kinase ABL20044
Tyrosine-protein kinase FRK0044
G protein-coupled receptor kinase 60033
Tyrosine-protein kinase ZAP-700022
Tyrosine-protein kinase SYK0044
26S proteasome regulatory subunit 6B0044
Mitogen-activated protein kinase 80145
Mitogen-activated protein kinase 90044
Dual specificity mitogen-activated protein kinase kinase 40022
Dual specificity mitogen-activated protein kinase kinase 30044
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha1023
Casein kinase I isoform alpha0044
Casein kinase I isoform delta0044
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0022
MAP kinase-activated protein kinase 20145
Cyclin-dependent kinase 80022
Elongation factor Tu, mitochondrial0044
Choline-phosphate cytidylyltransferase A0022
Cysteine--tRNA ligase, cytoplasmic0044
Casein kinase I isoform epsilon0044
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0044
Dual specificity protein kinase CLK10044
Dual specificity protein kinase CLK20044
Dual specificity protein kinase CLK30044
Glycogen synthase kinase-3 alpha0044
Glycogen synthase kinase-3 beta0145
Cyclin-dependent kinase 70044
Cyclin-dependent kinase 90044
Ras-related protein Rab-27A0033
Tyrosine-protein kinase Blk0123
Interleukin-1 receptor-associated kinase 10044
Ribosomal protein S6 kinase alpha-30145
Cytoplasmic tyrosine-protein kinase BMX0123
cAMP-dependent protein kinase catalytic subunit PRKX0022
Serine/threonine-protein kinase Nek20044
Serine/threonine-protein kinase Nek30044
Serine/threonine-protein kinase Nek40022
Tyrosine-protein kinase JAK304311
Dual specificity mitogen-activated protein kinase kinase 60044
Serine/threonine-protein kinase PLK10235
Death-associated protein kinase 10022
LIM domain kinase 10044
LIM domain kinase 20044
Mitogen-activated protein kinase 120123
Mitogen-activated protein kinase 100044
Tyrosine--tRNA ligase, cytoplasmic0044
5'-AMP-activated protein kinase subunit gamma-10044
5'-AMP-activated protein kinase catalytic subunit alpha-20022
Ephrin type-B receptor 30044
Ephrin type-A receptor 50044
Ephrin type-B receptor 40044
Ephrin type-B receptor 10022
Ephrin type-A receptor 40044
Adenylate kinase 2, mitochondrial0044
Adenosine kinase0044
Hormonally up-regulated neu tumor-associated kinase0022
Serine/threonine-protein kinase SIK10022
Receptor-interacting serine/threonine-protein kinase 40022
Ras-related protein Rab-100044
Cell division control protein 2 homolog0022
Actin-related protein 30044
Actin-related protein 20033
Calcium-dependent protein kinase 10022
GTP-binding nuclear protein Ran0044
Casein kinase II subunit alpha0022
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta0022
SRSF protein kinase 20022
Casein kinase I isoform gamma-20044
Mitogen-activated protein kinase kinase kinase 90022
Serine/threonine-protein kinase PknB0022
Cyclin-dependent kinase 30033
Cyclin-dependent kinase-like 10022
Cyclin-dependent kinase 60044
Cyclin-dependent-like kinase 5 0145
Cyclin-dependent kinase 160044
Cyclin-dependent kinase 170044
ATP-dependent 6-phosphofructokinase, platelet type0044
Protein kinase C epsilon type0123
Dual specificity mitogen-activated protein kinase kinase 10044
Angiopoietin-1 receptor0022
Mitogen-activated protein kinase kinase kinase 100022
DNA topoisomerase 2-beta01512
Protein kinase C theta type0044
Activin receptor type-10044
Macrophage-stimulating protein receptor0044
Focal adhesion kinase 10044
Protein kinase C zeta type0022
Protein kinase C delta type0044
Tyrosine-protein kinase BTK0145
Tyrosine-protein kinase receptor TYRO30022
Cyclin-dependent kinase 180033
Activated CDC42 kinase 10044
Epithelial discoidin domain-containing receptor 10044
Tyrosine-protein kinase ITK/TSK0123
Myotonin-protein kinase0022
Mitogen-activated protein kinase kinase kinase kinase 20044
Mitogen-activated protein kinase kinase kinase 120022
Tyrosine-protein kinase Mer0033
Serine/threonine-protein kinase 40044
5'-AMP-activated protein kinase catalytic subunit alpha-10044
Serine/threonine-protein kinase PAK 10022
Dual specificity mitogen-activated protein kinase kinase 50044
Mitogen-activated protein kinase 70044
Serine/threonine-protein kinase PAK 20044
Serine/threonine-protein kinase 30044
Mitogen-activated protein kinase kinase kinase 10044
cGMP-dependent protein kinase 20022
Integrin-linked protein kinase0044
Rho-associated protein kinase 10044
Non-receptor tyrosine-protein kinase TNK10044
Serine/threonine-protein kinase PRP4 homolog0022
Receptor-interacting serine/threonine-protein kinase 10022
Calcium/calmodulin-dependent protein kinase type II subunit beta0022
Calcium/calmodulin-dependent protein kinase type II subunit gamma0044
Calcium/calmodulin-dependent protein kinase type II subunit delta0044
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0044
Activin receptor type-2B0044
Bone morphogenetic protein receptor type-20044
Protein-tyrosine kinase 60044
cGMP-dependent protein kinase 1 0044
Cyclin-dependent kinase 130044
Calcium/calmodulin-dependent protein kinase type 10022
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0044
Protein-tyrosine kinase 2-beta0044
Maternal embryonic leucine zipper kinase0044
Structural maintenance of chromosomes protein 1A0033
Chromodomain-helicase-DNA-binding protein 40044
Peroxisomal acyl-coenzyme A oxidase 10033
Serine/threonine-protein kinase D10022
Serine/threonine-protein kinase 380022
Receptor tyrosine-protein kinase erbB-40123
Ribosomal protein S6 kinase alpha-20022
Ephrin type-A receptor 70033
Delta(24)-sterol reductase0033
Ribosomal protein S6 kinase alpha-10044
Dual specificity testis-specific protein kinase 10044
Myosin light chain kinase, smooth muscle0145
Mitogen-activated protein kinase 110145
Serine/threonine-protein kinase STK110044
Rhodopsin kinase GRK10022
NT-3 growth factor receptor0022
Serine/threonine-protein kinase N10044
Serine/threonine-protein kinase N20044
Mitogen-activated protein kinase 140156
Calcium/calmodulin-dependent protein kinase type IV0044
Mitogen-activated protein kinase kinase kinase 110044
BDNF/NT-3 growth factors receptor0022
Mitogen-activated protein kinase 60022
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform0022
Discoidin domain-containing receptor 20044
AP2-associated protein kinase 10145
Myosin light chain kinase 30044
Serine/threonine-protein kinase SBK10022
Mitogen-activated protein kinase kinase kinase 190022
Putative heat shock protein HSP 90-beta 20044
Serine/threonine-protein kinase TNNI3K0022
Leucine-rich repeat serine/threonine-protein kinase 20022
Serine/threonine-protein kinase MRCK alpha0044
Serine/threonine-protein kinase MRCK gamma0044
Acyl-CoA dehydrogenase family member 100044
Serine/threonine-protein kinase Nek50022
Serine/threonine-protein kinase N30022
Serine/threonine-protein kinase ULK30044
Dual serine/threonine and tyrosine protein kinase0022
Mitogen-activated protein kinase kinase kinase 150022
Uncharacterized protein FLJ452520044
Acyl-CoA dehydrogenase family member 110033
Serine/threonine-protein kinase/endoribonuclease IRE20044
Serine/threonine-protein kinase MARK20044
ATP-dependent RNA helicase DHX300044
Serine/threonine-protein kinase TAO10044
STE20-related kinase adapter protein alpha0044
Myosin-140044
AarF domain-containing protein kinase 10044
Serine/threonine-protein kinase tousled-like 20022
Serine/threonine-protein kinase 32C0022
Serine/threonine-protein kinase pim-30022
ATP-dependent RNA helicase DDX420022
Serine/threonine-protein kinase VRK20022
Myosin light chain kinase family member 40022
Homeodomain-interacting protein kinase 10022
Calcium/calmodulin-dependent protein kinase type 1D0022
Mitogen-activated protein kinase kinase kinase kinase 30044
Cyclin-dependent kinase-like 30022
MAP kinase-activated protein kinase 50145
Serine/threonine-protein kinase BRSK20022
Serine/threonine-protein kinase NIM10022
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0022
Serine/threonine-protein kinase ULK20022
Misshapen-like kinase 10044
Serine/threonine-protein kinase DCLK20022
Calcium/calmodulin-dependent protein kinase kinase 10022
Casein kinase I isoform alpha-like0022
Homeodomain-interacting protein kinase 40022
Myosin-IIIa0022
Ankyrin repeat and protein kinase domain-containing protein 10022
Serine/threonine-protein kinase Nek110022
Atypical kinase COQ8A, mitochondrial0044
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0044
Mitogen-activated protein kinase 150044
Serine/threonine-protein kinase Nek90044
Serine/threonine-protein kinase BRSK10022
Serine/threonine-protein kinase 350022
Serine/threonine-protein kinase Nek70022
Rhodopsin kinase GRK70022
Serine/threonine-protein kinase 32A0022
Myosin-IIIb0022
ATP-dependent RNA helicase DDX10044
Dual specificity tyrosine-phosphorylation-regulated kinase 20022
Cyclin-dependent kinase-like 20022
Mitogen-activated protein kinase kinase kinase kinase 10044
Serine/threonine-protein kinase Sgk30022
Atypical kinase COQ8B, mitochondrial0022
Aurora kinase B0044
MAP/microtubule affinity-regulating kinase 40033
Calcium/calmodulin-dependent protein kinase type 1G0044
Serine/threonine-protein kinase Nek10044
Cyclin-dependent kinase 150022
PAS domain-containing serine/threonine-protein kinase0044
Calcium/calmodulin-dependent protein kinase kinase 20044
EKC/KEOPS complex subunit TP53RK0044
SRSF protein kinase 10022
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0044
Mitogen-activated protein kinase kinase kinase 50044
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha0022
Mitogen-activated protein kinase kinase kinase 30044
Eukaryotic translation initiation factor 2-alpha kinase 10044
Serine/threonine-protein kinase RIO10022
MAP kinase-interacting serine/threonine-protein kinase 10022
Serine/threonine-protein kinase RIO20022
Cyclin-dependent kinase 190022
Transient receptor potential cation channel subfamily M member 60022
Testis-specific serine/threonine-protein kinase 10022
Serine/threonine-protein kinase 330022
Nucleolar GTP-binding protein 10044
Serine/threonine-protein kinase D20044
Serine/threonine-protein kinase DCLK30022
NUAK family SNF1-like kinase 20033
RNA cytidine acetyltransferase0044
Serine/threonine-protein kinase SIK20044
Myosin light chain kinase 2, skeletal/cardiac muscle0022
STE20-like serine/threonine-protein kinase 0044
Serine/threonine-protein kinase TAO30044
Homeodomain-interacting protein kinase 20022
Tyrosine-protein kinase Srms0022
Homeodomain-interacting protein kinase 30022
Serine/threonine-protein kinase PLK30224
dCTP pyrophosphatase 10044
Dual specificity protein kinase CLK40044
MAP kinase-interacting serine/threonine-protein kinase 20022
Serine/threonine-protein kinase Nek60022
Casein kinase I isoform gamma-10044
Serine/threonine-protein kinase PAK 60033
SNF-related serine/threonine-protein kinase0022
Serine/threonine-protein kinase LATS20022
Serine/threonine-protein kinase 360022
Phenylalanine--tRNA ligase beta subunit0044
BMP-2-inducible protein kinase0044
Obg-like ATPase 10033
Midasin0044
Interleukin-1 receptor-associated kinase 40044
Serine/threonine-protein kinase 32B0022
Mitogen-activated protein kinase kinase kinase 200044
Cyclin-dependent kinase 120044
Serine/threonine-protein kinase PLK20224
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130033
Serine/threonine-protein kinase MARK10022
Serine/threonine-protein kinase pim-20022
Serine/threonine-protein kinase PAK 50022
Serine/threonine-protein kinase 260044
eIF-2-alpha kinase GCN20022
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0044
Serine/threonine-protein kinase NLK0044
Serine/threonine-protein kinase 17A0022
STE20/SPS1-related proline-alanine-rich protein kinase0022
Ephrin type-A receptor 60022
5'-AMP-activated protein kinase subunit gamma-20044
Serine/threonine-protein kinase TBK10246
Septin-90044
Death-associated protein kinase 20022
Ribosomal protein S6 kinase alpha-60044
TRAF2 and NCK-interacting protein kinase0044
Serine/threonine-protein kinase tousled-like 10022
Serine/threonine-protein kinase TAO20044
Long-chain-fatty-acid--CoA ligase 50033
ALK tyrosine kinase receptor0022
SRSF protein kinase 30022
Serine/threonine-protein kinase ICK0044
Cyclin-dependent kinase 11A0022
Aurora kinase C0022
Calcium/calmodulin-dependent protein kinase type II subunit alpha0022
RAC-gamma serine/threonine-protein kinase0044
Serine/threonine-protein kinase 38-like0033
Microtubule-associated serine/threonine-protein kinase 10022
Serine/threonine-protein kinase SIK30044
Mitogen-activated protein kinase kinase kinase 20044
Thyroid hormone receptor-associated protein 30044
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0033
Mitogen-activated protein kinase kinase kinase kinase 50044
Receptor-interacting serine/threonine-protein kinase 30044
Serine/threonine-protein kinase MRCK beta0044
Interleukin-1 receptor-associated kinase 30044
Serine/threonine-protein kinase 240044
Casein kinase I isoform gamma-30044
Mitogen-activated protein kinase kinase kinase 40044
thioredoxin glutathione reductase9009
P532002
activating transcription factor 6190019
peripheral myelin protein 22 isoform 1120012
hemoglobin subunit beta3003
M-phase phosphoprotein 89009
Bile salt export pump017017
Protein-arginine deiminase type-40707
histone acetyltransferase KAT2A isoform 1170017
Gamma-aminobutyric acid type B receptor subunit 20213
Gamma-aminobutyric acid type B receptor subunit 20202
Gamma-aminobutyric acid type B receptor subunit 10213
Gamma-aminobutyric acid type B receptor subunit 10101
Membrane-associated progesterone receptor component 10022
Serine/threonine-protein kinase ATR0022
MAP kinase-activated protein kinase 30011
Uncharacterized aarF domain-containing protein kinase 50033
Rab-like protein 30022
Isoleucine--tRNA ligase, mitochondrial0022
Chain A, Betaine ABC transporter permease and substrate binding protein0011
Chain A, Osmoprotection protein (ProX)0011
Chain A, Glycine betaine/carnitine/choline-binding protein0022
Chain A, Glycine betaine/carnitine/choline-binding protein0022
Chain A, Glycine betaine/carnitine/choline-binding protein0022
Chain A, Glycine betaine/carnitine/choline-binding protein0022
Proton-coupled amino acid transporter 10303
Glutamate receptor ionotropic, NMDA 2D0112
Glutamate receptor ionotropic, NMDA 3B0112
Muscarinic acetylcholine receptor M10134
Muscarinic acetylcholine receptor M30134
Muscarinic acetylcholine receptor M40134
Muscarinic acetylcholine receptor M50134
Muscarinic acetylcholine receptor M20134
Fatty acid-binding protein, intestinal0314
Peroxisome proliferator-activated receptor alpha0022
Peroxisome proliferator-activated receptor delta0011
Peroxisome proliferator-activated receptor gamma03711
Peroxisome proliferator-activated receptor gamma0033
Peroxisome proliferator-activated receptor delta0011
Glutamate receptor ionotropic, NMDA 10112
Peroxisome proliferator-activated receptor alpha0135
Glutamate receptor ionotropic, NMDA 2A0112
Glutamate receptor ionotropic, NMDA 2B0112
Glutamate receptor ionotropic, NMDA 2C0112
Glutamate receptor ionotropic, NMDA 3A0112
caspase-1 isoform alpha precursor5005
Caspase-74004
Nuclear receptor subfamily 1 group I member 20077
Endothelin receptor type B1102
Endothelin receptor type B0213
Endothelin-1 receptor1214
Endothelin receptor type B0011
Deoxyhypusine synthase0101
Sodium/bile acid cotransporter0404
Endothelin-1 receptor0101
Angiotensin-converting enzyme 0202
Kappa-type opioid receptor0113
Cathepsin B0101
Cathepsin B0101
Chain A, Vitamin D Nuclear Receptor0011
Vitamin D3 receptor0011
Vitamin D-binding protein0011
Cytochrome P450 1A20304
Androgen receptor0516
Vitamin D3 receptor03410
Cytochrome P450 2C9 019122
Vitamin D3 receptor0113
Retinoic acid receptor RXR-alpha0033
Cytochrome P450 2C190809
Vitamin D3 receptor0022
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0011
Vitamin D3 receptor0112
Transporter0101
Vitamin D3 receptor A0022
Solute carrier family 22 member 50001
Solute carrier family 22 member 50001
Solute carrier family 22 member 160001
Solute carrier family 22 member 210001
Solute carrier family 22 member 50001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0002
Beta-lactamase 0001
Beta-lactamase 0101
Beta-lactamase 0002
Metallo-beta-lactamase type 20013
Metallo-beta-lactamase VIM-11 0002
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20002
Beta-lactamase 0001
Metallo-beta-lactamase VIM-19 0002
Beta-lactamase 0001
Beta-lactamase 0002
Metallo-beta-lactamase0002
Beta-lactamase 0101
Albumin0369
Beta-lactamase SHV-10001
Beta-lactamase SHV-10002
Beta-lactamase0002
Solute carrier family 15 member 10202
B2 metallo-beta-lactamase 0002
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 15 member 20202
Metallo-beta-lactamase VIM-130002
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20002
Beta-lactamase 0002
Beta-lactamase Toho-10001
Beta-lactamase 0001
Solute carrier family 22 member 60306
Solute carrier family 22 member 70203
Metallo-beta-lactamase0002
Solute carrier family 15 member 20202
Beta-lactamase 0001
Beta-lactamase 0002
Metallo-b-lactamase 0002
BlaVIM-1 0002
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 22 member 80305
Beta-lactamase 0002
Carbapenem-hydrolyzing beta-lactamase KPC0002
Histamine H3 receptor0104
Beta-lactamase class B VIM-2 0013
Solute carrier family 22 member 110204
Solute carrier family 22 member 80203
Beta-lactamase VIM-1 0002
Solute carrier family 22 member 70203
GALC protein4004
FAD-linked sulfhydryl oxidase ALR0001
Carbonic anhydrase 120205
Carbonic anhydrase 90306
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
Spike glycoprotein0145
Replicase polyprotein 1ab0246
glucose-6-phosphate 1-dehydrogenase isoform b0101
Transmembrane protease serine 20145
Dihydrofolate reductase 0303
DNA ligase0101
Riboflavin-binding protein0235
Major prion protein0022
Amyloid-beta precursor protein2507
Histidine-rich protein PFHRP-II0203
Procathepsin L0145
Replicase polyprotein 1a0145
Replicase polyprotein 1ab0145
Replicase polyprotein 1ab0246
Spike glycoprotein0101
Replicase polyprotein 1ab0448
Alpha-2C adrenergic receptor0606
DNA ligase 10101
Beta-secretase 10101
Calcium-dependent protein kinase 10011
MO15-related protein kinase Pfmrk 0101
DNA ligase A0101
Sigma intracellular receptor 20303
Phosphoethanolamine N-methyltransferase0101
Angiotensin-converting enzyme 2 0145
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
60 kDa chaperonin0303
60 kDa heat shock protein, mitochondrial0404
Glycine receptor subunit alpha-10011
10 kDa heat shock protein, mitochondrial0404
Thiosulfate sulfurtransferase0404
60 kDa chaperonin 0404
10 kDa chaperonin 0404
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10203
Solute carrier family 22 member 20203
Solute carrier family 22 member 1 0708
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit alpha-42103
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-22103
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-50101
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0001
Neuronal acetylcholine receptor subunit alpha-60101
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70101
Solute carrier family 22 member 10405
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100101
Solute carrier family 22 member 20405
5-hydroxytryptamine receptor 3E0101
5-hydroxytryptamine receptor 3B0101
Beta-2 adrenergic receptor0101
5-hydroxytryptamine receptor 1A0101
5-hydroxytryptamine receptor 2C0203
Angiotensin-converting enzyme0707
Dipeptidyl peptidase 40101
5-hydroxytryptamine receptor 2A0405
D0202
5-hydroxytryptamine receptor 1A0505
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
Alpha-2A adrenergic receptor0202
Alpha-1D adrenergic receptor0101
Sodium-dependent dopamine transporter0202
Alpha-1D adrenergic receptor0808
5-hydroxytryptamine receptor 1B0202
5-hydroxytryptamine receptor 1D0202
Gastrin/cholecystokinin type B receptor0101
5-hydroxytryptamine receptor 1F0202
5-hydroxytryptamine receptor 2B0101
5-hydroxytryptamine receptor 70101
Alpha-1A adrenergic receptor0101
Alpha-1B adrenergic receptor0101
5-hydroxytryptamine receptor 3A0202
5-hydroxytryptamine receptor 3A0101
D(2) dopamine receptor0202
5-hydroxytryptamine receptor 40112
Neutral alpha-glucosidase AB0101
5-hydroxytryptamine receptor 4 0012
Nuclear receptor subfamily 3 group C member 3 0606
5-hydroxytryptamine receptor 3D0101
5-hydroxytryptamine receptor 2A0101
5-hydroxytryptamine receptor 3C0101
5-hydroxytryptamine receptor 3B0202
Heparanase0011
NPC intracellular cholesterol transporter 1 precursor4004
Sodium-dependent noradrenaline transporter0101
Tryptophan 5-hydroxylase 10101
Aldo-keto reductase family 1 member B10101
Aromatase0101
Sodium-dependent serotonin transporter0303
Histamine H1 receptor0404
5-hydroxytryptamine receptor 70303
Sigma intracellular receptor 20303
Sodium-dependent serotonin transporter0101
Sodium-dependent dopamine transporter0101
Transporter0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50202
perilipin-10202
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0202
Beta-lactamase0101
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0102
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0202
Alpha-ketoglutarate-dependent dioxygenase FTO0202
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10505
General amino-acid permease GAP10001
importin subunit beta-1 isoform 13003
snurportin-13003
GTP-binding nuclear protein Ran isoform 11001
streptokinase A precursor0044
endonuclease IV5005
PAX80001
Smad3100010
nuclear receptor subfamily 0 group B member 10101
atrial natriuretic peptide receptor 2 precursor3003
ras-related protein Rab-9A4004
steroidogenic factor 10101
Solute carrier family 22 member 30303
Tubulin alpha-1A chain0213
Tubulin beta chain0213
Plasma kallikrein0003
Tubulin beta-4A chain0225
Tubulin beta chain0225
Tubulin alpha-3C chain0225
Tubulin alpha-1B chain0225
Tubulin alpha-4A chain0225
Tubulin beta-4B chain0225
Vesicular acetylcholine transporter0101
Tubulin beta-3 chain0225
Tubulin beta-2A chain0225
Tubulin polymerization-promoting protein0011
Tubulin beta-8 chain0225
Tubulin beta-2B chain0303
Tubulin alpha-3E chain0225
Tubulin alpha-1A chain0225
Similar to alpha-tubulin isoform 1 0202
Similar to alpha-tubulin isoform 1 0202
CREB-binding protein1001
Tubulin alpha-1C chain0225
Tubulin beta-6 chain0225
Tubulin beta-2B chain0225
Tubulin beta-1 chain0225
B2 bradykinin receptor0101
Dihydrofolate reductase0709
Dihydrofolate reductase0202
Chymotrypsinogen A0102
Beta-lactamase0202
Beta-lactamase0002
Beta-galactosidase0102
Choline O-acetyltransferase0101
Ectonucleotide pyrophosphatase/phosphodiesterase family member 20202
PH domain leucine-rich repeat-containing protein phosphatase 20101
Chymotrypsin-C0101
nonstructural protein 17007
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a180018
Solute carrier family 22 member 30101
atrial natriuretic peptide receptor 1 precursor2002
Glucocorticoid receptor012421
Glycine receptor subunit alpha-1012012
Glycine receptor subunit beta012012
Glycine receptor subunit alpha-2012012
Glycine receptor subunit alpha-3012012
Potassium voltage-gated channel subfamily A member 10213
TAR DNA-binding protein 43100010
Multidrug and toxin extrusion protein 10606
Sodium- and chloride-dependent creatine transporter 10101
Thymidine kinase 2 0101
Probable deoxycytidylate deaminase0001
Cytidine deaminase0002
AAA family ATPase 0002
Reverse transcriptase/RNaseH 0238
Hsf1 protein0011
Aldo-keto reductase family 1 member B100101
UDP-glucuronosyltransferase 1A90104
Transient receptor potential cation channel subfamily A member 10011
Cytochrome c oxidase subunit 20101
Transthyretin0126
Interleukin-80101
Calcium/calmodulin-dependent protein kinase type II subunit alpha0101
Aldo-keto reductase family 1 member B10202
UDP-glucuronosyltransferase 2B70308
UDP-glucuronosyltransferase 1-60405
UDP-glucuronosyltransferase 1A1 0408
UDP-glucuronosyltransferase 1A40203
Sodium- and chloride-dependent GABA transporter 10101
C-X-C chemokine receptor type 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Prostaglandin G/H synthase 2 0101
UDP-glucuronosyltransferase 1A30002
UDP-glucuronosyltransferase 2B10 0202
Sodium- and chloride-dependent betaine transporter0101
Cytochrome P450 2J2011011
Prostaglandin G/H synthase 20101
Prostaglandin G/H synthase 1 0101
UDP-glucuronosyltransferase 1A70102
UDP-glucuronosyltransferase 1A100103
Solute carrier family 22 member 80103
Beta-lactamase OXA-70001
Voltage-dependent L-type calcium channel subunit alpha-1C0404
Voltage-dependent L-type calcium channel subunit alpha-1D0303
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Histamine H1 receptor0023
Histamine N-methyltransferase0001
Calcium release-activated calcium channel protein 10101
Protein orai-20101
Protein orai-30101
Histamine H4 receptor0202
Capsid protein 0011
Serine/threonine-protein kinase B-raf 0101
Genome polyprotein 0213
chaperonin-containing TCP-1 beta subunit homolog1001
thyrotropin-releasing hormone receptor6006
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
eyes absent homolog 2 isoform a2002
lethal(3)malignant brain tumor-like protein 1 isoform I1001
relaxin receptor 1 isoform 11001
Flavin reductase (NADPH)0022
large T antigen0202
Enoyl-[acyl-carrier-protein] reductase [NADH]0204
Pantothenate synthetase0202
acid sphingomyelinase3003
apical membrane antigen 1, AMA16006
Type IV secretion-like conjugative transfer relaxase protein TraI 0101
LMP1 [Human herpesvirus 4]0001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0202
transactivating tegument protein VP16 [Human herpesvirus 1]0303
nuclear receptor coactivator 3 isoform a0202
Prothrombin0012
Regulatory protein E20011
DNA topoisomerase 10102
Polyunsaturated fatty acid lipoxygenase ALOX150303
DNA topoisomerase 20001
Serum paraoxonase/arylesterase 10202
Caspase-30101
DNA topoisomerase 2-alpha 0001
Integrase 0101
NPC1-like intracellular cholesterol transporter 10101
NPC1-like intracellular cholesterol transporter 10101
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase 0101
Xanthine dehydrogenase/oxidase0304
Nuclear receptor ROR-gamma0101
Xanthine dehydrogenase/oxidase0202
serine-protein kinase ATM isoform a1001
Fatty acid-binding protein, liver0101
Cruzipain0101
Peroxisome proliferator-activated receptor alpha0011
Disintegrin and metalloproteinase domain-containing protein 171001
Chain A, BCL-2-RELATED PROTEIN A10011
unnamed protein product0101
heat shock protein HSP 90-alpha isoform 20001
bcl-2-like protein 11 isoform 10011
Rap guanine nucleotide exchange factor 34004
Steroid 17-alpha-hydroxylase/17,20 lyase0101
Heme oxygenase 1 0101
Lanosterol 14-alpha demethylase0112
Aromatase0202
Cytochrome P450 11B1, mitochondrial0101
Cytochrome P450 11B2, mitochondrial0101
Heme oxygenase 20101
Malate dehydrogenase, cytoplasmic0101
Cytochrome P450 1440011
Steroid C26-monooxygenase0011
Steroid C26-monooxygenase0011
Mycocyclosin synthase0011
Lanosterol 14-alpha demethylase0011
Lanosterol 14-alpha demethylase0011
Lanosterol 14-alpha demethylase0516
Sterol 14-alpha demethylase0011
Sterol 14-alpha demethylase0112
14-alpha sterol demethylase 0011
heat shock protein 90, putative0001
likely tRNA 2'-phosphotransferase0101
corticotropin-releasing hormone receptor 20112
corticotropin releasing factor-binding protein0112
glycogen synthase kinase-3 beta isoform 10044
5'-nucleotidase0101
Adenosine receptor A30101
Adenosine deaminase 0103
Carbonic anhydrase 40306
Carbonic anhydrase0204
Carbonic anhydrase 150204
Chain A, Uracil Phosphoribosyltransferase0101
Skn7p0001
Vpr2002
Thymidylate synthase0404
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
Chain A, Dihydrofolate reductase0011
lysosomal alpha-glucosidase preproprotein4004
DNA polymerase beta2002
Thymidylate synthase0404
Dihydrofolate reductase0449
Alpha-synuclein5106
Folylpolyglutamate synthase, mitochondrial0104
Solute carrier organic anion transporter family member 1A30104
Folylpolyglutamate synthase, mitochondrial0104
Multidrug resistance associated protein0103
Carbonic anhydrase 30103
Glucose-6-phosphate 1-dehydrogenase0202
Carbonic anhydrase 60205
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Carbonic anhydrase 5A, mitochondrial0104
Carbonic anhydrase 70104
Adenosine receptor A10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
6-phosphogluconate dehydrogenase, decarboxylating0202
Holo-[acyl-carrier-protein] synthase0101
Carbonic anhydrase 130103
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10606
Carbonic anhydrase 140104
Carbonic anhydrase 5B, mitochondrial0104
Chain A, DEOXYNUCLEOSIDE KINASE0101
Equilibrative nucleoside transporter 10101
Cannabinoid receptor 20011
Guanylate cyclase soluble subunit alpha-10011
Guanylate cyclase soluble subunit beta-10011
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor2002
Metabotropic glutamate receptor 80202
Glutathione reductase, mitochondrial0707
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Glutamate receptor 10314
Glutamate receptor 30314
Glutamate receptor 40314
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, kainate 50101
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
Purine nucleoside phosphorylase0202
Hypoxanthine-guanine phosphoribosyltransferase0002
Ricin0101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Purine nucleoside phosphorylase 0012
Shiga toxin subunit A0101
Guanine deaminase0102
Cyclic GMP-AMP synthase0202
Toll-like receptor 90101
Toll-like receptor 70101
Neutral amino acid transporter A0101
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0101
Amino acid transporter0101
3-oxoacyl-[acyl-carrier-protein] synthase 3 0101
N-glycosylase/DNA lyase0101
Polyphenol oxidase 20406
Formamidopyrimidine-DNA glycosylase0101
DNA gyrase subunit A0101
DNA gyrase subunit B0101
Cytochrome P450 2A60303
Macrophage migration inhibitory factor0101
Endonuclease III-like protein 10101
DNA gyrase subunit B0202
DNA gyrase subunit A0202
Isocitrate lyase0101
Putative FAD-containing monooxygenase MymA0101
Dihydrofolate reductase0202
Endonuclease 8-like 10101
Parkin5005
phosphoethanolamine/phosphocholine phosphatase isoform 10101
serine/threonine-protein kinase PLK16006
Sodium/potassium-transporting ATPase subunit alpha-1 0303
Sodium/potassium-transporting ATPase subunit beta-10303
Microtubule-associated protein tau0101
Sodium/potassium-transporting ATPase subunit alpha-30303
Sodium/potassium-transporting ATPase subunit beta-20303
Indoleamine 2,3-dioxygenase 10404
Fatty acid synthase0909
Sodium/potassium-transporting ATPase subunit alpha-20303
Sodium/potassium-transporting ATPase subunit beta-30303
Sodium/potassium-transporting ATPase subunit gamma0303
WD repeat-containing protein 50303
Histone-lysine N-methyltransferase 2A0303
Sodium/potassium-transporting ATPase subunit alpha-40303
Cytosolic endo-beta-N-acetylglucosaminidase0303
Indoleamine 2,3-dioxygenase 20404
matrix metalloproteinase 1, partial0011
pyruvate kinase1001
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Amine oxidase [flavin-containing] A0202
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Chain A, Antigen Cd11a (p180)0101
PINK12002
isocitrate dehydrogenase 1, partial1001
bcl-2-related protein A10101
Integrin beta-20101
Intercellular adhesion molecule 10101
Neutrophil elastase0101
Integrin alpha-L0112
Adenosine receptor A10505
Rap guanine nucleotide exchange factor 41001
Acyl-CoA:cholesterol acyltransferase 0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
UDP-glucose 6-dehydrogenase0101
UDP-glucose 6-dehydrogenase0101
Purine nucleoside phosphorylase0011
UDP-glucuronosyltransferase 1A1 0101
Beta-lactamase TEM0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0012
Beta-lactamase IMP-1 0001
Beta-lactamase 0001
Chain A, Breast cancer type 1 susceptibility protein2002
microphthalmia-associated transcription factor isoform 90101
Tumor necrosis factor0101
Neuraminidase0101
Platelet-activating factor receptor1002
Cystathionine gamma-lyase0202
Cystine/glutamate transporter0101
Hydroxyacid oxidase 10101
Dopamine beta-hydroxylase 0202
Lactoperoxidase0101
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Large neutral amino acids transporter small subunit 10303
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
ClpP2002
Thymidylate synthase 0101
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX122002
DNA polymerase eta isoform 12002
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0303
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0404
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Pteridine reductase 10202
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10204
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0101
Dihydrofolate reductase0202
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Nuclear receptor subfamily 1 group I member 20011
Thioredoxin reductase 0101
Flavodoxin0001
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20112
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Stromelysin-10202
Matrilysin0101
Multidrug transporter MdfA0101
Matrix metalloproteinase-90101
Protein mono-ADP-ribosyltransferase PARP150101
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
Nuclear receptor corepressor 10101
Integrin beta-10101
Leukotriene A-4 hydrolase0101
Integrin alpha-40101
Nuclear receptor corepressor 20101
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
Inosine-5'-monophosphate dehydrogenase 1 0202
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A80001
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial0202
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial0101
Atrial natriuretic peptide receptor 10101
Acetylcholinesterase0101
Cholinesterase0202
Cholinesterase0202
Cholesteryl ester transfer protein0101
D-amino-acid oxidase0101
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
Hydroxycarboxylic acid receptor 20213
D-aspartate oxidase0101
Hydroxycarboxylic acid receptor 20112
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
tumor necrosis factor2002
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
Phospholipase A2, membrane associated0102
Potassium voltage-gated channel subfamily A member 50101
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Adenosine receptor A2a0202
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
C-terminal-binding protein 11001
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Leukotriene B4 receptor 10001
Transient receptor potential cation channel subfamily A member 10011
Potassium channel subfamily K member 2 0101
Beta-2 adrenergic receptor0001
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Leukotriene B4 receptor 20001
Mcl-10101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Bifunctional cytochrome P450/NADPH--P450 reductase0011
Potassium-transporting ATPase subunit beta0101
Potassium-transporting ATPase alpha chain 10101
Potassium-transporting ATPase alpha chain 10101
Bombesin receptor subtype-30011
Potassium-transporting ATPase subunit beta0101
Potassium-transporting ATPase alpha chain 20001
Glutathione S-transferase omega-10202
Muscarinic acetylcholine receptor0101
Trypsin0101
Coagulation factor VII0101
Tissue factor0202
Tyrosine-protein phosphatase non-receptor type 10303
Fatty acid-binding protein 50101
Multidrug and toxin extrusion protein 20101
Succinyl-diaminopimelate desuccinylase0101
Sigma non-opioid intracellular receptor 10303
Adenosine deaminase0101
Adenosine deaminase 0101
Chain D, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)0101
Chain A, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)0101
Chain A, Beta-arrestin 10011
luciferase0001
Estrogen receptor0415
Progesterone receptor0416
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glutamine synthetase0011
Nociceptin receptor0011
Estrogen receptor beta0314
dual specificity protein phosphatase 30101
low molecular weight phosphotyrosine protein phosphatase isoform c0101
tyrosine-protein phosphatase non-receptor type 22 isoform 10101
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Estrogen receptor0011
Beta-hexosaminidase subunit alpha0102
Beta-hexosaminidase subunit beta0101
Substance-K receptor0101
Dihydrofolate reductase0101
Low molecular weight phosphotyrosine protein phosphatase0101
Dipeptidyl peptidase 40202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Trace amine-associated receptor 50011
Estrogen receptor beta0011
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Multidrug and toxin extrusion protein 10101
N0101
NPYLR7B0022
cystic fibrosis transmembrane conductance regulator0101
tumor susceptibility gene 101 protein1001
Major prion protein0101
DNA-directed RNA polymerase subunit alpha0101
DNA-directed RNA polymerase subunit omega0101
DNA-directed RNA polymerase subunit beta'0101
DNA-directed RNA polymerase subunit beta0101
Phospholipase A2, membrane associated0101
Acidic phospholipase A2 20101
Trypanothione reductase0202
Aldehyde oxidase 10101
Aldehyde oxidase0101
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Insulin-degrading enzyme0101
Urease subunit alpha0101
Urease subunit beta0101
NAD(+) hydrolase SARM10101
NS5 0011
Polymerase basic protein 20011
RNA-directed RNA polymerase catalytic subunit0011
Polymerase acidic protein0011
Adenosylhomocysteinase0002
Adenosine receptor A10101
Genome polyprotein0011
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain H, Immunoglobulin Igg1 Heavy chain0011
Chain L, Immunoglobulin Igg1 Lambda Light Chain0011
Chain A, DODECIN0011
Chain A, DODECIN0011
Chain C, DODECIN0011
Chain E, DODECIN0011
nuclear factor NF-kappa-B p105 subunit isoform 11001
DNA-directed RNA polymerase subunit beta0101
NH(3)-dependent NAD(+) synthetase0101
Cytochrome P450 2B60011
Arylacetamide deacetylase0102
Caspase-10101
Solute carrier organic anion transporter family member 1A20102
DNA-directed RNA polymerase subunit beta0101
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, 146aa long hypothetical transcriptional regulator0011
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain B, Anthranilate phosphoribosyltransferase0101
Chain C, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Anthranilate phosphoribosyltransferase0101
photoreceptor-specific nuclear receptor0101
3-hydroxy-3-methylglutaryl-coenzyme A reductase0101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Eukaryotic translation initiation factor 4E0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0426
Peptidyl-prolyl cis-trans isomerase FKBP1B0022
Peptidyl-prolyl cis-trans isomerase FKBP50202
Programmed cell death protein 40011
Regulatory-associated protein of mTOR0101
Dual specificity testis-specific protein kinase 20022
Target of rapamycin complex subunit LST80101
Serine/threonine-protein kinase mTOR 0101
Chain A, Mineralocorticoid receptor0101
Chain A, Mineralocorticoid receptor0101
Chain A, Ribosomal protein S6 kinase alpha-10101
Chain X, Tyrosine-protein kinase Lyn0101
Chain A, Dual specificity protein kinase TTK0011
Chain A, Dual specificity protein kinase TTK0011
DNA polymerase beta0202
Cytochrome P450 3A50101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Splicing factor 3B subunit 30101
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
Solute carrier organic anion transporter family member 1A50001
Proliferating cell nuclear antigen0101
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 4C10101
Monocarboxylate transporter 80001
Bile acid receptor0112
Solute carrier organic anion transporter family member 1C10001
Chain A, Tyrosine-protein kinase0101
Chain A, Tyrosine-protein kinase0101
Chain A, Tyrosine-protein kinase JAK20101
Serine/threonine-protein kinase Sgk10101
Myosin light chain kinase, smooth muscle0011
Tubulin alpha-1A chain0011
Tyrosine-protein kinase JAK30101
Tyrosine-protein kinase JAK20101
Tyrosine-protein kinase JAK30101
procathepsin L isoform 1 preproprotein0101
Amine oxidase [flavin-containing] B0101
Amine oxidase [flavin-containing] A 0101
Amine oxidase [flavin-containing] B0202
Forkhead box protein M10202
ATP-binding cassette sub-family C member 80101
ATP-sensitive inward rectifier potassium channel 110101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Alkaline phosphatase, tissue-nonspecific isozyme0101
Intestinal-type alkaline phosphatase0101
Indoleamine 2,3-dioxygenase 10102
Tryptophan 2,3-dioxygenase0102
Carbonic anhydrase0002
SLC16A10 protein0002
Uracil nucleotide/cysteinyl leukotriene receptor0101
Carbonic anhydrase 0002
Tryprostatin B synthase0001
Carbonic anhydrase0002
Carbonic anhydrase0002
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Carbonic anhydrase 0002
Monocarboxylate transporter 100002
Phospholipase A-2-activating protein0101
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Taste receptor type 2 member 140001
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Solute carrier family 2, facilitated glucose transporter member 90112
Ubiquitin carboxyl-terminal hydrolase 20101
Ileal sodium/bile acid cotransporter0101
G-protein coupled bile acid receptor 10011
M1-family alanyl aminopeptidase0101
Cocaine esterase0101
Aldo-keto reductase family 1 member A10101
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Receptor-type tyrosine-protein phosphatase F0101
Tyrosine-protein phosphatase non-receptor type 20101
Tyrosine-protein phosphatase non-receptor type 60101
Tyrosine-protein phosphatase non-receptor type 110101
Thymidine kinase, cytosolic0204
Adenosylhomocysteinase0101
RNA-directed RNA polymerase 0112
Ectonucleoside triphosphate diphosphohydrolase 10001
Thymidine kinase, cytosolic 0001
Thymidylate kinase0101
Thymidine kinase 0102
Protease 0112
Thymidine kinase0102
twin arginine protein translocation system - TatA protein0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]