Page last updated: 2024-12-08

pentigide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

pentigide: synthetic peptide derived from the Fc region of human lgE; RN given refers to the all-L-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID162960
CHEBI ID135842
SCHEMBL ID29861
MeSH IDM0120080

Synonyms (42)

Synonym
pentigetide
pentyde
pentyde (tn)
62087-72-3
pentigetide (usan/inn)
D05423
CHEBI:135842
asp-ser-asp-pro-arg
human ige pentapeptide
pentapeptide dsdpr
ige pentapeptide
pentigetida [inn-spanish]
unii-yg3j18t1ux
pentigetidum [inn-latin]
l-arginine, n(sup 2)-(1-(n-(n-l-alpha-aspartyl-l-seryl)-l-alpha-aspartyl)-l-prolyl)-
n(sup 2)-(1-(n-(n-l-alpha-aspartyl-l-seryl)-l-alpha-aspartyl)-l-prolyl)-l-arginine
pentigetid
pentigetida
pentigide
pentigetidum
yg3j18t1ux ,
pentigetide [usan:inn]
hamburger pentapeptide
pentapeptide-dsdpr
l-arginine, n(sup 2)-(1-(n-(n-l-.alpha.-aspartyl-l-seryl)-l-.alpha.-aspartyl)-l-prolyl)-
l-.alpha.-aspartyl-l-seryl-l-.alpha.-aspartyl-l-prolyl-l-arginine
pentigetide [inn]
n(sup 2)-(1-(n-(n-l-.alpha.-aspartyl-l-seryl)-l-.alpha.-aspartyl)-l-prolyl)-l-arginine
pentigetide [mi]
pentigetide [usan]
SCHEMBL29861
(2s)-2-{[(2s)-1-[(2s)-2-[(2s)-2-[(2s)-2-amino-3-carboxypropanamido]-3-hydroxypropanamido]-3-carboxypropanoyl]pyrrolidin-2-yl]formamido}-5-[(diaminomethylidene)amino]pentanoic acid
aspartylserylaspartylprolylarginine
(s)-2-((s)-1-((s)-2-((s)-2-((s)-2-amino-3-carboxypropanamido)-3-hydroxypropanamido)-3-carboxypropanoyl)pyrrolidine-2-carboxamido)-5-guanidinopentanoic acid
l-aspartyl-l-seryl-l-aspartyl-l-prolyl-l-arginine
KQDIGHIVUUADBZ-PEDHHIEDSA-N
n~2~-[{1-[2-({2-[(2-amino-3-carboxy-1-hydroxypropylidene)amino]-1,3-dihydroxypropylidene}amino)-3-carboxypropanoyl]pyrrolidin-2-yl}(hydroxy)methylidene]arginine
DTXSID30977675
Q27294502
(2s)-2-[[(2s)-1-[(2s)-2-[[(2s)-2-[[(2s)-2-amino-3-carboxypropanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid
HY-P3746
CS-0620399

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" The incidence and types of adverse experiences were similar between treatment groups and there were no reports of sedation or fatigue in the pentigetide group."( Pentigetide nasal solution: a multicenter study evaluating efficacy and safety in patients with seasonal allergic rhinitis.
Daigle, A; Findlay, S; Haddad, Z; Hampel, F; Kniker, W; Mansmann, HC; Ratner, P; Rosen, J; Ziering, R, 1991
)
0.28

Dosage Studied

ExcerptRelevanceReference
"The safety, dosage and efficacy of human IgE pentapeptide (HEPP) was evaluated in 12 patients with IgE-mediated atopic disease."( Safety and efficacy of human IgE pentapeptide.
Cohen, GA; Hamburger, RN; O'Connor, RD, 1984
)
0.27
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
oligopeptideA peptide containing a relatively small number of amino acids.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (60.00)18.7374
1990's3 (30.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials4 (30.77%)5.53%
Reviews1 (7.69%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (61.54%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]