omeprazole has been researched along with Polymyositis in 4 studies
Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.
omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.
Polymyositis: Diseases characterized by inflammation involving multiple muscles. This may occur as an acute or chronic condition associated with medication toxicity (DRUG TOXICITY); CONNECTIVE TISSUE DISEASES; infections; malignant NEOPLASMS; and other disorders. The term polymyositis is frequently used to refer to a specific clinical entity characterized by subacute or slowly progressing symmetrical weakness primarily affecting the proximal limb and trunk muscles. The illness may occur at any age, but is most frequent in the fourth to sixth decade of life. Weakness of pharyngeal and laryngeal muscles, interstitial lung disease, and inflammation of the myocardium may also occur. Muscle biopsy reveals widespread destruction of segments of muscle fibers and an inflammatory cellular response. (Adams et al., Principles of Neurology, 6th ed, pp1404-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| " It is unclear if polymyositis was triggered by interaction of the statin with omeprazole and/or gemfibrozil, or if it developed secondary to long-term use of atorvastatin only." | 5.39 | Statin-associated polymyositis following omeprazole treatment. ( Flores, RM; Kanth, R; Shah, MS, 2013) |
| "Polymyositis occurring in patients treated with omeprazole has been signalled as a possible adverse drug reaction (ADR) by the New Zealand Intensive Medicines Monitoring Programme (IMMP) and the WHO Collaborating Centre for International Drug Monitoring: the Uppsala Monitoring Centre (UMC)." | 4.83 | Myopathy including polymyositis: a likely class adverse effect of proton pump inhibitors? ( Clark, DW; Strandell, J, 2006) |
| " It is unclear if polymyositis was triggered by interaction of the statin with omeprazole and/or gemfibrozil, or if it developed secondary to long-term use of atorvastatin only." | 1.39 | Statin-associated polymyositis following omeprazole treatment. ( Flores, RM; Kanth, R; Shah, MS, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kanth, R | 1 |
| Shah, MS | 1 |
| Flores, RM | 1 |
| Potekhin, NP | 1 |
| rozhnov, IuA | 1 |
| Orlov, FA | 1 |
| Kurmashev, AF | 1 |
| Karanik, AR | 1 |
| Ruseĭkin, VM | 1 |
| Balbir-Gurman, A | 1 |
| Brook, OR | 1 |
| Chermesh, I | 1 |
| Braun-Moscovici, Y | 1 |
| Clark, DW | 1 |
| Strandell, J | 1 |
3 reviews available for omeprazole and Polymyositis
| Article | Year |
|---|---|
[Medical case of successful therapy of polymyositis by high doses of glucocorticoid].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Enzyme Inhibitors; Glucocorticoids; Huma | 2009 |
Pneumatosis cystoides intestinalis in scleroderma-related conditions.
Topics: Abdomen, Acute; Adrenal Cortex Hormones; Adult; Aged; Connective Tissue Diseases; Diagnosis, Differe | 2012 |
Myopathy including polymyositis: a likely class adverse effect of proton pump inhibitors?
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adverse Drug Reaction Reporting Systems; Enzyme Inhibitors; | 2006 |
1 other study available for omeprazole and Polymyositis
| Article | Year |
|---|---|
Statin-associated polymyositis following omeprazole treatment.
Topics: Anticholesteremic Agents; Atorvastatin; Drug Interactions; Esophagitis; Gemfibrozil; Heptanoic Acids | 2013 |