Conditions > Keratoconus
Page last updated: 2024-09-27

Keratoconus

A noninflammatory, usually bilateral protrusion of the cornea, the apex being displaced downward and nasally. It occurs most commonly in females at about puberty. The cause is unknown but hereditary factors may play a role. The -conus refers to the cone shape of the corneal protrusion. (From Dorland, 27th ed)

Synonyms(1)

Synonym
Keratoconus

Research Excerpts

Overview

ExcerptReference
"Keratoconus is a condition in which the cornea assumes a complex irregular curvature caused by central corneal thinning."( Cheng, KH; Kok, JH, 1991)
"Keratoconus is a corneal thinning disorder usually localized to the paracentral cornea."( McLeish, WM; Rubsamen, PE, 1991)
"Keratoconus is a disease characterized by thinning and scarring of the central cornea."( Baum, JL; Smith, BD; Yue, BY, 1983)
"Keratoconus is also associated with genetic diseases like Down syndrome, Marfan syndrome, and other conditions related to collagen disturbance and biochemical abnormalities in protein synthesis."( Thalasselis, A, 1995)
"Keratoconus is an ocular disorder in which the central cornea becomes thin, conical and frequently scarred."( Easty, DL; Hoh, HB; Littleton, M; Smith, VA, 1995)
"Keratoconus is a disease characterized by thinning and scarring of the central portion of the cornea."( Sugar, J; Yue, BY; Zhou, L, 1996)
"Keratoconus is characterized by thinning and scarring of the central region of the cornea."( Feder, RS; Fukuchi, T; Sugar, J; Twining, SS; Whitelock, RB; Yue, BY; Zhou, L, 1997)
"Keratoconus is a progressive ectatic disease of the cornea."( Balázs, E; Berta, A; Csutak, A; Módis, L; Takács, L, 1999)
"Keratoconus is a diseasethat has been recognized clinically for many years."( Brown, DJ; Kenney, MC; Rajeev, B, 2000)
"Keratoconus is a progressive disease that thins and scars the corneal stroma."( Li, Y; Maruyama, Y; Sugar, J; Wang, X; Yue, BY, 2001)
"SKC mouse keratoconus is a potential model for a subset of human keratoconus, which is a disease entity with heterogeneous pathogeneses."( Adachi, W; Hiai, H; Honma, Y; Kinoshita, S; Kobayashi, Y; Matsushima, Y; Tachibana, M, 2002)
"Keratoconus is a debilitating corneal thinning disease that principally develops in the second and third decades of life."( Brookes, NH; Clover, GM; Loh, IP; Poole, CA; Sherwin, T, 2003)
"Keratoconus is a noninflammatory, corneal thinning disorder leading to mixed myopic and irregular astigmatism and implicated as a major reason for cornea transplantations in the Western world."( Anderson, T; Brown, D; Chalukya, M; Kenney, MC; Morales, L; Nesburn, A; Small, K; Udar, N, 2004)
"Keratoconus is essentially a bilateral but asymmetric corneal degeneration."( Chopra, I; Jain, AK, 2005)
"Keratoconus is a bilateral non-inflammatory corneal ectasia with an incidence of approximately 1 per 2000 in the general population."( Gatzioufas, Z; Thanos, S, 2008)
"Unilateral keratoconus is a rare entity."( Chalvatzis, N; Ilari, L; Liarakos, VS; Mavrikakis, I; Papaparaskeva, K, 2010)
"Keratoconus is a condition that causes corneal ectasia and reduced vision in young adults."( Aslanides, IM; Kolli, S, 2010)
"Keratoconus is a predominantly bilateral form of corneal degeneration that is associated with central thinning and cone-shaped bulging of the cornea usually accompanied by a progressive reduction in visual acuity."( Guthoff, R; Hovakimyan, M; Knappe, S; Stachs, O; Zhivov, A, 2011)
"Keratoconus is characterized by the thinning of corneal stroma, resulting in reduced vision."( Dada, R; Nayak, B; Pathak, D; Sharma, N; Singh, M; Sinha, R; Tandon, R; Titiyal, JS, 2011)
"Keratoconus is a degenerating disease of the eye which causes an irregularly shaped cornea leading to severe impairment of vision."( Balasubramanian, SA; Pye, DC; Willcox, MD, 2012)
"Keratoconus is a complex disease and it is suspected to have a genetic origin, although the specific gene responsible for keratoconus has not been identified."( Cunha, Pda S; de Aguiar, MJ; Frasson, M; Gonçalves-Dornelas, H; Leão, LL; Stofanko, M; Viana, MM, 2013)
"Keratoconus is a progressive, ectatic disease of the cornea leading to thinning and highly irregular astigmatism."( Maier, P; Reinhard, T, 2013)
"Prevalence of keratoconus is variable in different parts of the world."( Gokhale, NS, 2013)
"Keratoconus is a common ectatic disorder occurring in more than 1 in 1,000 individuals."( Rao, SK, 2013)
"Keratoconus is a non-inflammatory corneal disease, which involves changes of the corneal shape, due to thinning of the corneal stroma."( Błasiak, J; Kurowska, AK; Szaflik, J; Szaflik, JP; Wójcik, KA, 2013)
"Keratoconus is a corneal disorder characterized by a thinning of stromal tissue, and the affected patients have induced astigmatism and visual impairment."( Beuerman, RW; Kadaba, A; Mehta, JS; Myint, HH; Tian, D; Yam, GH; Yusoff, NZ; Zhou, L, 2015)
"Keratoconus is a bilateral and asymmetric corneal ectasia."( Aminifard, MN; Jafarzadeh, R; Khallaghi, H; Mohammadi, M, 2015)
"Keratoconus is a bilateral disease characterized by progressive corneal thinning leading to irregular astigmatism that results in significant visual impairment."( Dudakova, L; Jirsova, K; Liskova, P, 2015)
"Keratoconus is a condition of the eye that affects approximately 1 in 2000 people."( Amissah-Arthur, KN; Bunce, C; Evans, JR; Hamada, S; Karim, R; McDonnell, PJ; Patwary, S; Sykakis, E, 2015)
"Keratoconus is characterized by a neurotrophic deficit and altered nerve morphology that CXL treatment does not address, despite providing a positive biomechanical effect in the stroma."( Fragkiskou, S; Guimarães, P; Lagali, N; Parissi, M; Poletti, E; Randjelovic, S; Ruggeri, A; Utheim, TP; Wihlmark, TB, 2016)
"Keratoconus is an anti-inflammatory eye disorder that debilitated cornea unable to reserve the normal structure contrary to the IOP in the eye."( Karimi, A; Kudo, S; Navidbakhsh, M; Razaghi, R; Sera, T, 2017)
"Since keratoconus is generally localized, the efficacy of collagen cross-linking (CXL) treatments could be improved by stiffening only the weakened parts of the cornea."( Han, Z; Larin, KV; Li, J; Singh, M; Twa, MD; Vantipalli, S, 2017)
"Keratoconus is a noninflammatory disease of the cornea associated with progressive thinning and conical shape."( Hartmann, U; Langenbucher, A; Seitz, B; Stachon, A; Stachon, T; Szentmáry, N, 2017)
"Keratoconus is an ocular degeneration characterized by the thinning of corneal stroma that may lead to varying degrees of myopia and visual impairment."( Deva, JP; Lau, AY; Lee, KR; Ng, JB; Poh, RY; Subrayan, V; Tan, JA, 2016)
"Keratoconus is a relatively common (1 : 2000) bilateral disease leading to a change in biochemical and biomechanical corneal structure as well as thinning and ectasia."( Herwig-Carl, MC; Holz, FG; Kohlhaas, M; Löffler, KU; Müller, PL, 2018)
"Keratoconus is a progressive condition caused by the thinning of the cornea, which eventually deforms the front surface of the eye into a cone shape leading to ghosting, multiple images, glare, and several other vision problems."( Kandzija, N; Khutoryanskiy, VV, 2017)
"Keratoconus is a debilitating condition with a disproportionately high impact on health resources and vision-specific quality of life."( Gokul, A; McGhee, CNJ; Meyer, J; Patel, D; Vellara, H; Ziaei, M, 2019)
"Keratoconus is a condition in which the cornea progressively thins and protrudes in a conical shape, severely affecting refraction and vision."( Baird, PN; Burdon, KP; Bykhovskaya, Y; Charlesworth, JC; Craig, JE; Hewitt, AW; Jensen, RA; Li, X; Lucas, SEM; MacGregor, S; Mackey, DA; McComish, BJ; Mills, RA; Mitchell, P; Rabinowitz, YS; Richardson, AJ; Rotter, JI; Sahebjada, S; Taylor, KD; Tenen, A; Wang, JJ; Willoughby, CE, 2020)
"Keratoconus is a common and progressive eye disease characterized by thinning and tapering of the cornea."( Aytekin, E; Çakmak, HB; Çalış, S; Öztürk, N; Pehlivan, SB; Polat, HK; Vural, İ, 2020)
"Keratoconus is a disorder of the shape of the cornea in which the normally round dome-shaped clear front window of the eye (cornea) thins progressively leading to a cone-like bulge."( Bunce, C; Chowdhury, K; Doré, CJ; Larkin, DFP, 2020)
"Keratoconus is a bilateral progressive noninflammatory degenerative disease of the cornea characterized by corneal thinning, irregular astigmatism, and subsequent visual impairment."( Fard, AM; Lillvis, JH; Nader, ND; Reynolds, AL, 2020)
"Keratoconus is a bilateral, asymmetric and progressive corneal disease."( Catania, F; Fossati, G; Legrottaglie, EF; Montericcio, A; Raimondi, R; Vinciguerra, P; Vinciguerra, R, 2021)
"Keratoconus is the most common corneal dystrophy."( Hawkins, BS; Kuo, IC; Lindsley, KB; Ng, SM; Ren, M, 2021)
"Keratoconus is classified as a corneal ectasia and is a multifactorial disease."( Bulirsch, LM; Herwig-Carl, MC; Holz, FG; Kohlhaas, M; Loeffler, KU; Saßmannshausen, M; Weber, C, 2022)
"CXL for keratoconus is a highly effective treatment, as evident by its effects on the outcome measures: Delta Kmax and Delta LogMAR."( Frucht-Pery, J; Shmueli, O; Solomon, A; Wajnsztajn, D; Zur, K, 2022)
"Keratoconus is a common corneal disease that causes vision loss."( Çankaya, C; Çınar, A; Fırat, İT; Fırat, M; Tuncer, T, 2022)
"Keratoconus is a disorder that results in visual loss from increased corneal high-order aberrations and irregular astigmatism and reduces quality of life."( Borchert, GA; Kandel, H; Watson, SL, 2022)
"Keratoconus is a progressive corneal thinning disorder that can lead to vision loss."( Angelo, L; Gokul Boptom, A; McGhee, C; Ziaei, M, 2022)
"Keratoconus is a progressive visually impairing disorder."( Avni-Zauberman, N; Barequet, IS; Berger, Y; Matani, A; Rotenberg, M; Vorobichik Berar, O, 2023)
"Keratoconus is a progressive visually impairing disorder."( Avni-Zauberman, N; Barequet, IS; Berger, Y; Matani, A; Rotenberg, M; Vorobichik Berar, O, 2023)
"Keratoconus is rare and is not considered a risk factor for visual impairment."( Abdi, S; Bamdad, S; Fazil, N; Kangari, H; Masoumi, SJ; Mohaghegh, S; Rahmani, S; Shahbazi, S, 2023)
"Keratoconus is a degenerative disorder of the cornea leading to a protrusion and thinning with loss of visual acuity."( Berendschot, TTJM; Dickman, MM; Nuijts, RMMA; Roy, AS; Shetty, R; van den Biggelaar, FJHM; Vandevenne, MMS; Visser, N; Wijdh, RHJ; Winkens, B; Wisse, RPL, 2023)

Context

ExcerptReference
"Tear proteomics in keratoconus has been a topic of substantial discussion and speculation over many years."( Balasubramanian, SA; Pye, DC; Willcox, MD, 2012)
"Keratoconus has been halted and the patient has a binocular best corrected visual acuity of -0."( Abbondanza, G; Abbondanza, M; De Felice, V, 2017)
"Keratoconus has classically been defined as a noninflammatory disorder, although recent studies show elevated levels of inflammatory markers suggesting that keratoconus could be, at least in part, an inflammatory condition."( Alcalde, I; Alfonso, JF; Ferrara, G; García, B; García-Suárez, O; González, J; Lisa, C; Merayo-Lloves, J; Quirós, LM; Vazquez, F, 2017)
"Patients with keratoconus have significant higher corneal densitometry values compared to healthy controls."( Alnawaiseh, M; Eter, N, 2018)

Actions

ExcerptReference
"Mild-moderate keratoconus-affected eyes that underwent accelerated corneal collagen crosslinking (CXL) treatment and had 6 and 12 months of follow-up were reviewed retrospectively."( Chan, CC; Elbaz, U; Goldich, Y; Lichtinger, A; Rootman, DS; Shen, C; Slomovic, AR; Zauberman, NA, 2014)

Treatment

ExcerptReference
"In this study,we tried to treat keratoconus patients with this method to stop the progression of corneal ectasia."( Seiler, T; Spörl, E; Wollensak, G, 2003)
"It has been shown that the treatment of keratoconus with riboflavin/ultraviolet A (UVA) causes significant stiffening of the cornea due to cross-linking."( Kohlhaas, M; Pillunat, LE; Schilde, T; Spoerl, E, 2008)
"A new surgical technique for the treatment of keratoconus is presented."( Daxer, A; Mahmoud, HA; Venkateswaran, RS, 2010)
"Corneal cross-linking for the treatment of keratoconus has been tested in animal trials and proven clinically."( Guthoff, R; Heisterkamp, A; Hovakimyan, M; Knappe, S; Krüger, A; Stachs, O; Wree, A; Zhivov, A, 2011)
"CXL procedure is a safe treatment for keratoconus, yields good visual results, and reduces the progression of the disease, but long follow-up is necessary."( Bernilla, C; Henriquez, MA; Izquierdo, L; Mannis, M; Zakrzewski, PA, 2011)
"During the UVA-cross-linking treatment in keratoconus patients, the UVA rays are partially absorbed in the stroma of the riboflavin-loaded cornea."( Faust, M; Gericke, A; Lorenz, K; Stoffelns, BM; Tubic-Grozdanis, M; Vetter, JM, 2011)
"Corneal cross-linking (CXL) is a treatment for keratoconus that eliminates the need for keratoplasty in most patients."( Brummer, G; Conrad, GW; Littlechild, S; McCall, S; Zhang, Y, 2011)
"CXL plays an important role in the treatment of keratoconus and may in the future delay or eliminate the need for a corneal transplantation."( Tahzib, NG; van der Leij, AG, 2011)
"This technique can be used to treat progressive keratoconus in the cornea as well as progressive myopia in the sclera."( Cheong, Y; Choi, S; Jin, KH; Jung, GB; Lee, HJ; Lee, SC; Park, HK, 2013)
"To evaluate staged combined treatment for keratoconus with intrastromal corneal ring segment (ICRS) implantation followed by corneal collagen crosslinking (CXL) with riboflavin-ultraviolet-A (UVA) and then toric implantable collagen copolymer phakic intraocular lens (pIOL) implantation."( Coşkunseven, E; Hafezi, F; Jankov, MR; Kymionis, GD; Richoz, O; Sharma, DP, 2013)
"Corneal cross-linking is widely used to treat keratoconus."( Böhringer, D; Brunner, T; Dollak, S; Geerling, G; Kutchoukov, B; Lang, SJ; Mackert, MJ; Maier, P; Messmer, EM; Reinhard, T, 2015)
"To determine whether CXL treatment of keratoconus results in normalization of subbasal nerve density and architecture up to 5 years after treatment."( Fragkiskou, S; Guimarães, P; Lagali, N; Parissi, M; Poletti, E; Randjelovic, S; Ruggeri, A; Utheim, TP; Wihlmark, TB, 2016)
"To evaluate a four-stage combined treatment for keratoconus including intrastromal corneal ring segment (ICRS) implantation followed by corneal cross-linking (CXL), toric phakic intraocular lens (IOL) implantation, and topography-guided photorefractive keratectomy (TG-PRK)."( Coskunseven, E; Grentzelos, MA; Kymionis, GD; Pallikaris, I; Sahin, O; Sharma, DP, 2017)
"To describe a new technique for the treatment of keratoconus using corneal allogenic intrastromal ring segments (CAIRS)."( Agarwal, A; Jacob, S; Patel, SR; Raj, JM; Ramalingam, A; Saijimol, AI, 2018)
"These drugs treat keratoconus and dry eye syndrome, respectively."( Aserin, A; Garti, N; Garti-Levy, S; Lidich, N, 2019)
"Korean patients who were treated for keratoconus between September 2015 and January 2018 at Seoul St."( Chung, SH; Hwang, J; Kang, MJ, 2021)
"ATE-CXL is a safe and effective treatment for keratoconus patients."( Jian, W; Shen, Y; Sun, L; Tian, M; Zhang, X; Zhou, X, 2022)

Research

Studies (1,427)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990124 (8.69)23.3326
1990's49 (3.43)12.5806
2000's147 (10.30)18.1394
2010's732 (51.30)28.8240
2020's375 (26.28)9.53
DrugIndicatedRelationship StrengthStudiesTrials
malic acid0low10
lactic acid0low20
glycine0low20
glycerol0low10
nitric acid0low10
nitrites0low10
pyridoxal0low10
pyruvic acid0low10
spermidine0low10
uric acid0low20
urea0low20
1-anilino-8-naphthalenesulfonate0low20
acetazolamide0low70
pimagedine0low10
amiodarone0low10
azathioprine0low10
chloroquine0low20
cyclopentolate0low20
diclofenac0low20
dichlorphenamide0low10
valproic acid0low10
erythrosine0medium41
fluconazole0low10
gentamicin0medium31
glutaral0low10
guanethidine0low10
indomethacin0low20
2-propanol0low580
ketoconazole0low10
ofloxacin0low40
benoxinate0low10
pyranoprofen0medium11
procaine0low10
proxymetacaine0low10
sulforaphane0low10
tetracaine0low20
tolazoline0low10
tranexamic acid0low10
tropicamide0low10
prednisolone0medium201
estriol0low10
hydroxyproline0low80
thyroxine0low60
dextroamphetamine0low10
prednisolone acetate0low80
penicillamine0low10
prednisone0low20
estrone0low10
dehydroepiandrosterone0low20
idoxuridine0low30
pilocarpine0low50
triiodothyronine0low10
chloramphenicol0low20
aspartic acid0low10
lysine0low20
phenylephrine0low10
edetic acid0low20
tyrosine0low20
colchicine0low10
ornithine0low20
methandrostenolone0low10
tryptophan0low20
arginine0low30
perfluoroethane0low10
perflutren0low80
triamcinolone acetonide0low10
methylmethacrylate0medium11
methylprednisolone0low10
propoxycaine0low10
n-vinyl-2-pyrrolidinone0low10
tolonium chloride0low10
copper phthalocyanine0low20
betamethasone0low20
fluorometholone0medium21
nandrolone0low10
fusarium0low10
reticulin0low10
malondialdehyde0low40
gentian violet0low10
congo red0low10
dehydroepiandrosterone sulfate0low10
hydroxyethyl methacrylate0low10
deoxycytidine0low10
vancomycin0low50
d-alpha tocopherol0medium51
tocopherols0low10
selenomethionine0low10
fluorescein0medium61
sulfur hexafluoride0low70
mannose0low10
norleucine0low10
diadenosine tetraphosphate0medium31
mercury0low10
molybdenum0medium11
ruthenium0low10
titanium0medium33
tricalcium phosphate0low10
galactose0low10
triamcinolone0low10
transferrin0low20
glutamic acid0low10
cefazolin0low10
timolol0medium31
tobramycin0low40
substance p0low10
perfluoromethyldecalin0low10
propiconazole0low20
fomesafen0low30
gemcitabine0low10
triazoles0low20
tocophersolan0medium21
voriconazole0low30
prednisolone phosphate0low10
c.i. direct red 800low10
ketorolac tromethamine0medium11
fibrinogen0low10
homocysteine0low20
cobalt0medium11
imipenem, anhydrous0low10
fingolimod hydrochloride0low10
n(6)-carboxymethyllysine0low10
proline0low20
docetaxel anhydrous0medium11
levofloxacin0low20
moxifloxacin0low30
singlet oxygen0low10
atropine0low60
cortisone0low30
3-nitrotyrosine0low10
glycogen0low30
fibrin0low20
glucosamine0low30
elastin0low30
tibolone0low10
loteprednol etabonate0low10
betadex0low10
retinol0low10
tacrolimus0low10
cocaine0low10
keratan sulfate0low80
y 276320low10
bromochloroacetic acid0low50
phenylthiourea0low20
thiourea0low10
safranine t0low10
dermatan sulfate0low30
hydroxylysine0low10
alpha-chymotrypsin0low10
cathepsin g0low30
sphingosine0low10
quercetin0low20
dinoprostone0low40
dinoprost0low10
5-hydroxy-6,8,11,14-eicosatetraenoic acid0low10
prostaglandin a20low10
amphotericin b0low20
isotretinoin0low20
olopatadine hydrochloride0low10
4-hydroxy-2-nonenal0low10
sphingosine 1-phosphate0low10
codeine0low10
phenylephrine hydrochloride0low10
acitretin0low10
sirolimus0medium11
8-oxo-7,8-dihydrodeoxyguanine0low10
cysteine0low20
silicon0medium11
salubrinal0low10
selenium0low40
nystatin a10low10
glanatec0low10
indocyanine green0low20
scopolamine hydrobromide0low10
acid phosphatase0low50
oligonucleotides0low10
cellulose0low10
phenylmercuric acetate0low10
4-aminophenylmercuriacetate0low10
chitosan0low20
glycolipids0low10
interleukin-80low50
colistin0low10
p(1),p(5)-di(adenosine-5'-)pentaphosphate0medium11
methylcellulose0low10
vasoactive intestinal peptide0low10
chondroitin0low30
heparitin sulfate0low30
ascorbic acid0low50
epidermal growth factor0medium21
transforming growth factor beta0low190
cyclin d10low20
calpastatin0low20
vitamin b 120low30
cyclosporine0medium83
flavin mononucleotide0medium91
lactoferrin0low40
orabase0low10
chondroitin sulfates0medium41
exudates0low40
acyclovir0low10
deoxyguanosine0low20
guanine0low10
folic acid0low30
rifampin0low10
allopurinol0medium11
trypan blue0low20
8-hydroxy-2'-deoxyguanosine0low30
eye0medium632
concanavalin a0low10
trypsinogen0low10
leptin0low10
filipin0low10

Protein Targets (1,726)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain B, pheromone binding protein0011
Chain A, pheromone binding protein0011
Chain A, JmjC domain-containing histone demethylation protein 3A7007
Chain A, RNA-directed RNA polymerase NS50101
acid sphingomyelinase3003
thioredoxin reductase280028
USP1 protein, partial240024
TDP1 protein490049
vitamin D3 receptor isoform VDRA180018
importin subunit beta-1 isoform 13003
flap endonuclease 1120012
serine/threonine-protein kinase PLK15005
snurportin-13003
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1100010
GTP-binding nuclear protein Ran isoform 12002
DNA polymerase eta isoform 16006
DNA polymerase iota isoform a (long)190019
urokinase-type plasminogen activator precursor5005
plasminogen precursor5005
urokinase plasminogen activator surface receptor precursor5005
geminin370037
DNA polymerase kappa isoform 1140014
fibroblast growth factor 22 isoform 1 precursor0001
Mitogen-activated protein kinase 130101
Beta-lactamase0606
Transthyretin0127
Fatty acid-binding protein, intestinal0325
Fatty acid-binding protein, adipocyte0112
Cyclin-A20101
Cannabinoid receptor 10314
Cyclin-dependent kinase 20224
Choline O-acetyltransferase0202
Mitogen-activated protein kinase 120101
Guanine nucleotide-binding protein G4004
Fatty acid-binding protein 50011
Fatty acid-binding protein 50011
Mitogen-activated protein kinase 110112
Mitogen-activated protein kinase 140314
hypoxia-inducible factor 1 alpha subunit190019
RAR-related orphan receptor gamma390039
GLI family zinc finger 3470047
AR protein640064
aldehyde dehydrogenase 1 family, member A1290029
retinoic acid nuclear receptor alpha variant 1490049
retinoid X nuclear receptor alpha350035
estrogen nuclear receptor alpha690069
peroxisome proliferator-activated receptor delta250025
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a330033
activating transcription factor 6230023
v-jun sarcoma virus 17 oncogene homolog (avian)220022
Histone H2A.x160016
thyroid hormone receptor beta isoform a190019
heat shock protein beta-1190019
nuclear factor erythroid 2-related factor 2 isoform 1450045
lamin isoform A-delta10420042
Voltage-dependent calcium channel gamma-2 subunit190019
Glutamate receptor 2192122
Chain A, Putative fructose-1,6-bisphosphate aldolase9009
phosphopantetheinyl transferase230023
bromodomain adjacent to zinc finger domain 2B7007
euchromatic histone-lysine N-methyltransferase 2490049
pyruvate kinase PKM isoform a1001
Glycoprotein hormones alpha chain1001
Tubulin--tyrosine ligase0202
Microtubule-associated protein tau210022
Transient receptor potential cation channel subfamily A member 10011
Polyunsaturated fatty acid 5-lipoxygenase0303
Inositol monophosphatase 16006
Chain A, Avidin0022
Chain A, Avidin0022
Chain B, Avidin0022
Chain A, TYROSYL-DNA PHOSPHODIESTERASE160016
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Beta-lactamase8008
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Class Iii Chitinase Chia10101
Chain A, Carbonic anhydrase 130101
Chain A, Carbonic anhydrase II0101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase0101
Chain B, Carbonic anhydrase0101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0002
Carbonic anhydrase 0202
GALC protein3003
nuclear receptor subfamily 1, group I, member 3280028
cytochrome P450 family 3 subfamily A polypeptide 4290029
glucocorticoid receptor [Homo sapiens]570057
estrogen-related nuclear receptor alpha510051
Carbonic anhydrase 0202
Carbonic anhydrase 0303
arylsulfatase A150015
Carbonic anhydrase0303
Bloom syndrome protein isoform 1190019
peripheral myelin protein 22190019
survival motor neuron protein isoform d120012
muscleblind-like protein 1 isoform 17007
Gamma-aminobutyric acid receptor subunit pi182222
ATP-binding cassette sub-family C member 3032032
Multidrug resistance-associated protein 4033037
Carbonic anhydrase0202
Solute carrier family 22 member 60304
Carbonic anhydrase 1205111
Prolyl endopeptidase0202
Carbonic anhydrase-related protein 110102
Bile salt export pump055055
Glycogen phosphorylase, muscle form0202
Renin0202
Carbonic anhydrase 109119
Carbonic anhydrase 209118
Carbonic anhydrase 20202
Cytochrome P450 1A20404
Carbonic anhydrase 305111
Cathepsin B0101
Cytochrome P450 3A4019122
Steryl-sulfatase0203
5-hydroxytryptamine receptor 2C0415
Cytochrome P450 2C80404
Cytochrome P450 2D60707
Cytochrome P450 2A60314
Cytochrome P450 2C9 013115
5-hydroxytryptamine receptor 2A0618
Androgen receptor019019
Gamma-aminobutyric acid receptor subunit beta-1182222
Translocator protein0202
Gamma-aminobutyric acid receptor subunit delta182222
Gamma-aminobutyric acid receptor subunit gamma-2182222
Gamma-aminobutyric acid receptor subunit alpha-5182222
Gamma-aminobutyric acid receptor subunit alpha-3182222
Arachidonate 5-lipoxygenase-activating protein0101
Cytochrome P450 2B60213
Carbonic anhydrase 407112
Carbonic anhydrase 606111
Gamma-aminobutyric acid receptor subunit gamma-1182222
Gamma-aminobutyric acid receptor subunit alpha-2182222
Carbonic anhydrase 5A, mitochondrial0202
Adenosine receptor A10304
Serum paraoxonase/arylesterase 10303
Dipeptidyl peptidase 40103
Gamma-aminobutyric acid receptor subunit alpha-4182222
Gamma-aminobutyric acid receptor subunit gamma-3182222
Endochitinase0101
Gamma-aminobutyric acid receptor subunit alpha-6182222
Adenosine receptor A2a0304
5-hydroxytryptamine receptor 2B0415
Sodium-dependent serotonin transporter0517
Delta-type opioid receptor0303
Cytochrome P450 2C190808
Delta-type opioid receptor0203
Mu-type opioid receptor0213
Carbonic anhydrase 5A, mitochondrial06112
Carbonic anhydrase0406
Kappa-type opioid receptor0203
Carbonic anhydrase 706111
Carbonic anhydrase0101
D(1A) dopamine receptor1102
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Carbonic anhydrase0204
D(2) dopamine receptor0213
Gamma-aminobutyric acid receptor subunit alpha-1182222
Gamma-aminobutyric acid receptor subunit beta-3182222
Gamma-aminobutyric acid receptor subunit beta-2182222
Cholinesterase0202
Carbonic anhydrase 0101
Mu-type opioid receptor0213
Fatty-acid amide hydrolase 11304
Beta-carbonic anhydrase 10202
Carbonic anhydrase 20202
Glutamate receptor ionotropic, NMDA 2B07211
Squalene synthase0101
Neuronal acetylcholine receptor subunit alpha-70101
Carbonic anhydrase 908114
Carbonic anhydrase0101
Carbonic anhydrase, alpha family 0202
Carbonic anhydrase 0204
Carbonic anhydrase 30202
Carbonic anhydrase0306
Carbonic anhydrase0205
Carbonic anhydrase 0202
Sigma intracellular receptor 20202
Delta carbonic anhydrase0202
Sigma non-opioid intracellular receptor 10213
Renin0101
Carbonic anhydrase 0204
Endochitinase A10101
Multidrug resistance-associated protein 10101
Carbonic anhydrase 130315
GABA theta subunit182222
Canalicular multispecific organic anion transporter 1030030
Carbonic anhydrase 40506
Carbonic anhydrase 150407
Acidic mammalian chitinase0101
Carbonic anhydrase 130609
Carbonic anhydrase 70101
Gamma-aminobutyric acid receptor subunit epsilon182222
Carbonic anhydrase 0101
Carbonic anhydrase 1405111
Carbonic anhydrase 0101
Carbonic anhydrase 2, isoform A 0101
Carbonic anhydrase 5B, mitochondrial06112
Luciferase180018
peroxisome proliferator activated receptor gamma330033
thyroid hormone receptor beta isoform 2370037
eyes absent homolog 2 isoform a2002
histone acetyltransferase KAT2A isoform 1130013
Bile salt export pump0909
Rap guanine nucleotide exchange factor 37007
Cellular tumor antigen p53440044
Rap guanine nucleotide exchange factor 43003
Chain E, Purine nucleoside phosphorylase0101
Chain A, HADH2 protein120012
Chain B, HADH2 protein120012
Chain A, ATP-DEPENDENT DNA HELICASE Q16006
Chain A, Ferritin light chain120012
Thymidine kinase 0303
GLS protein150015
Smad37007
thyroid stimulating hormone receptor220022
EWS/FLI fusion protein200020
hemoglobin subunit beta3003
atrial natriuretic peptide receptor 1 precursor3003
ubiquitin carboxyl-terminal hydrolase 2 isoform a6006
Solute carrier family 22 member 1 0409
Purine nucleoside phosphorylase0303
Thymidine kinase, cytosolic0204
POU domain, class 2, transcription factor 20002
Cytochrome P450 2J20404
Disintegrin and metalloproteinase domain-containing protein 174004
Purine nucleoside phosphorylase0033
Solute carrier family 22 member 60308
Thymidine kinase 0101
Solute carrier family 22 member 80306
Thymidine kinase0101
interleukin 8110011
estrogen receptor 2 (ER beta)260026
progesterone receptor320032
IDH1120012
transcriptional regulator ERG isoform 35005
ras-related protein Rab-9A5005
Polyphenol oxidase 20507
Hypoxanthine-guanine phosphoribosyltransferase0002
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase 0101
Adenosine receptor A2a0415
Xanthine dehydrogenase/oxidase0404
Nuclear receptor ROR-gamma0101
Xanthine dehydrogenase/oxidase0417
TAR DNA-binding protein 439009
Shiga toxin subunit A0202
Histamine H3 receptor0102
acetylcholinesterase140014
SMAD family member 2190019
ATAD5 protein, partial120012
Fumarate hydratase9009
NFKB1 protein, partial9009
PPM1D protein9009
SMAD family member 3190019
Thrombopoietin3003
caspase 7, apoptosis-related cysteine protease6006
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)180018
farnesoid X nuclear receptor230023
pregnane X nuclear receptor390039
G180018
cytochrome P450 2D6200020
polyprotein9009
caspase-36006
thyroid stimulating hormone receptor180018
cytochrome P450 2D6 isoform 1110011
cellular tumor antigen p53 isoform a8008
cytochrome P450 2C9 precursor8008
D(1A) dopamine receptor3003
chromobox protein homolog 1200020
potassium voltage-gated channel subfamily H member 2 isoform d120012
huntingtin isoform 25005
mitogen-activated protein kinase 1110011
serine/threonine-protein kinase mTOR isoform 14004
nuclear receptor ROR-gamma isoform 1130013
cytochrome P450 3A4 isoform 1180018
muscarinic acetylcholine receptor M1110011
lethal factor (plasmid)150015
Polyunsaturated fatty acid lipoxygenase ALOX15B91010
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Solute carrier organic anion transporter family member 1A40306
Voltage-dependent L-type calcium channel subunit alpha-1F0303
5-hydroxytryptamine receptor 40808
Lysine-specific demethylase PHF20101
Interferon beta270027
HLA class I histocompatibility antigen, B alpha chain 180018
Thyroid hormone receptor alpha0101
Receptor tyrosine-protein kinase erbB-20202
Integrin beta-36017
Tyrosine-protein kinase Fyn0314
ATP-dependent translocase ABCB10707
Aldo-keto reductase family 1 member B10909
Muscarinic acetylcholine receptor M2015220
Muscarinic acetylcholine receptor M4013116
ATP-dependent translocase ABCB1011215
Integrin alpha-IIb6017
Beta-1 adrenergic receptor0617
Muscarinic acetylcholine receptor M5011114
Alpha-2A adrenergic receptor011112
Adenosine receptor A30909
Thyroid hormone receptor alpha0336
Thyroid hormone receptor beta0336
Muscarinic acetylcholine receptor M1014320
Beta-3 adrenergic receptor0617
D(2) dopamine receptor0606
Alpha-1B adrenergic receptor012113
Lethal factor0101
Alpha-2B adrenergic receptor012113
Thyroid hormone receptor beta0202
Muscarinic acetylcholine receptor M3012115
ATP-dependent translocase ABCB10707
Substance-K receptor010010
D(1A) dopamine receptor0606
D(4) dopamine receptor0505
Carnitine O-palmitoyltransferase 2, mitochondrial0101
Sodium-dependent noradrenaline transporter 010111
Histamine H2 receptor0808
Endothelin-1 receptor0202
5-hydroxytryptamine receptor 2A0808
5-hydroxytryptamine receptor 2C0808
Lysine-specific demethylase 5A0101
B2 bradykinin receptor0202
Sodium-dependent serotonin transporter017219
Melanocortin receptor 40404
C-8 sterol isomerase0101
Melanocortin receptor 50404
Mu-type opioid receptor0819
D(3) dopamine receptor0606
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0101
Squalene synthase0101
Delta-type opioid receptor0808
Kappa-type opioid receptor0808
5-hydroxytryptamine receptor 2B0808
C-C chemokine receptor type 20202
Melanocortin receptor 30404
Alpha-1A adrenergic receptor011112
Histamine H2 receptor130014
5-hydroxytryptamine receptor 60404
Carnitine O-palmitoyltransferase 1, liver isoform0101
C-C chemokine receptor type 40303
Spike glycoprotein171321
Sodium channel protein type 7 subunit alpha0202
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
Sodium-dependent dopamine transporter 012113
Potassium voltage-gated channel subfamily H member 2014015
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Sodium channel protein type 5 subunit alpha0303
Squalene monooxygenase0101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Sodium channel protein type 9 subunit alpha0303
Lysine-specific demethylase 7A0101
Carnitine O-palmitoyltransferase 1, muscle isoform0101
Inositol hexakisphosphate kinase 1180018
Sodium channel protein type 2 subunit alpha0202
Ataxin-2170017
Sigma non-opioid intracellular receptor 10909
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0011
Sodium channel protein type 3 subunit alpha0202
Sodium channel protein type 11 subunit alpha0101
Histone lysine demethylase PHF80101
Sodium channel protein type 8 subunit alpha0202
Sodium channel protein type 10 subunit alpha0101
cytochrome P450 2C9, partial180018
ATP-dependent phosphofructokinase140014
Chain A, Cruzipain110011
vitamin D (1,25- dihydroxyvitamin D3) receptor260026
tumor necrosis factor4004
Nuclear receptor ROR-gamma130013
Aurora kinase B0213
Broad substrate specificity ATP-binding cassette transporter ABCG20617
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE220022
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
alpha-galactosidase3003
cytochrome P450 2C19 precursor7007
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0203
Nitric oxide synthase, brain 0002
Nitric oxide synthase, inducible0405
Nitric oxide synthase, inducible0115
Cationic amino acid transporter 30202
Chain A, Hyaluronidase, phage associated0101
thioredoxin glutathione reductase8008
nuclear factor erythroid 2-related factor 2 isoform 2130013
lethal(3)malignant brain tumor-like protein 1 isoform I2002
Pancreatic alpha-amylase0202
Albumin0112
Urease0304
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0404
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0102
Solute carrier family 23 member 10101
Metabotropic glutamate receptor 60225
Excitatory amino acid transporter 40202
Glutamate transporter homolog0011
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
5-hydroxytryptamine receptor 1D0102
Glutamate receptor ionotropic, NMDA 1 07211
Excitatory amino acid transporter 10304
Excitatory amino acid transporter 20304
Excitatory amino acid transporter 30304
Glutamate receptor ionotropic, NMDA 2A 06210
Glutamate receptor ionotropic, NMDA 2C06210
Metabotropic glutamate receptor 10124
Metabotropic glutamate receptor 20124
Carbonic anhydrase-like protein, putative0004
Glutamate receptor ionotropic, NMDA 2D06210
Glutamate receptor ionotropic, NMDA 3B06210
Glutamate receptor ionotropic, NMDA 3A06210
Chain A, 2-oxoglutarate Oxygenase120012
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta6006
short transient receptor potential channel 6 isoform 10011
Muscarinic acetylcholine receptor M107111
Muscarinic acetylcholine receptor M30519
Muscarinic acetylcholine receptor M40519
Muscarinic acetylcholine receptor M50519
Muscarinic acetylcholine receptor M206212
Muscarinic acetylcholine receptor M10012
Alpha-1D adrenergic receptor0606
Muscarinic acetylcholine receptor M40101
5-hydroxytryptamine receptor 70202
Reverse transcriptase/RNaseH 0012
Muscarinic acetylcholine receptor0112
P531001
aryl hydrocarbon receptor250025
peripheral myelin protein 22 isoform 18008
M-phase phosphoprotein 85005
ATPase family AAA domain-containing protein 5140014
Protein-arginine deiminase type-40101
Chain A, D-MALTODEXTRIN BINDING PROTEIN0011
Chain A, Limit Dextrinase0011
Chain A, Solute-binding protein0011
Chain A, Solute-binding protein0011
Chain B, SusD0011
Chain A, SusD0011
Chain A, SusD0011
Chain A, Alpha-hemolysin0011
Chain B, Alpha-hemolysin0011
Chain C, Alpha-hemolysin0011
Chain D, Alpha-hemolysin0011
Chain E, Alpha-hemolysin0011
Chain F, Alpha-hemolysin0011
Chain G, Alpha-hemolysin0011
pregnane X receptor100010
nuclear receptor subfamily 1, group I, member 2130013
galanin receptor type 30101
Glucocorticoid receptor018226
Glycine receptor subunit alpha-1018018
Glycine receptor subunit beta018018
Glycine receptor subunit alpha-2018018
Glycine receptor subunit alpha-3018018
ORF730011
apical membrane antigen 1, AMA15005
Solute carrier family 15 member 10101
Solute carrier family 22 member 110104
Solute carrier family 22 member 80101
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a150015
streptokinase A precursor0044
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Methionine--tRNA ligase, mitochondrial0011
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
Spike glycoprotein0134
Replicase polyprotein 1ab0235
glucose-6-phosphate 1-dehydrogenase isoform b0101
Transmembrane protease serine 20134
Dihydrofolate reductase 0101
DNA ligase0101
Riboflavin-binding protein0123
Major prion protein0011
Amyloid-beta precursor protein0707
Histidine-rich protein PFHRP-II0102
Procathepsin L0235
Replicase polyprotein 1a0235
Replicase polyprotein 1ab0235
Replicase polyprotein 1ab0639
Spike glycoprotein0101
Replicase polyprotein 1ab0639
Ribosyldihydronicotinamide dehydrogenase [quinone]0112
Alpha-2C adrenergic receptor0415
DNA ligase 10101
Serine/threonine-protein kinase mTOR0314
Nuclear receptor subfamily 4 group A member 20011
Beta-secretase 10303
Calcium-dependent protein kinase 10011
MO15-related protein kinase Pfmrk 0101
DNA ligase A0101
Sigma intracellular receptor 20101
Phosphoethanolamine N-methyltransferase0101
Angiotensin-converting enzyme 2 0134
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
Tryptophan 5-hydroxylase 10101
Gamma-aminobutyric acid receptor subunit alpha-10202
Gamma-aminobutyric acid receptor subunit beta-10202
Gamma-aminobutyric acid receptor subunit gamma-20202
D0101
5-hydroxytryptamine receptor 1A08210
Alpha-2B adrenergic receptor0415
Alpha-2C adrenergic receptor0415
Alpha-2A adrenergic receptor0415
Liver carboxylesterase 10102
Sodium-dependent dopamine transporter0415
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Gamma-aminobutyric acid receptor subunit beta-30202
5-hydroxytryptamine receptor 1B0516
5-hydroxytryptamine receptor 1D0112
5-hydroxytryptamine receptor 1F0112
5-hydroxytryptamine receptor 60112
Gamma-aminobutyric acid receptor subunit alpha-50202
5-hydroxytryptamine receptor 7 0112
Gamma-aminobutyric acid receptor subunit alpha-30202
5-hydroxytryptamine receptor 5A0112
5-hydroxytryptamine receptor 5B0112
5-hydroxytryptamine receptor 3A0112
Lysosomal Pro-X carboxypeptidase0101
Gamma-aminobutyric acid receptor subunit alpha-20202
Gamma-aminobutyric acid receptor subunit beta-20202
Gamma-aminobutyric acid receptor subunit alpha-40202
Gamma-aminobutyric acid receptor subunit epsilon0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Leukotriene B4 receptor 11102
Gamma-aminobutyric acid receptor subunit alpha-60202
Sodium-dependent dopamine transporter0202
5-hydroxytryptamine receptor 4 0112
Gamma-aminobutyric acid receptor subunit gamma-10202
Gamma-aminobutyric acid receptor subunit gamma-30202
5-hydroxytryptamine receptor 3B0112
Leukotriene B4 receptor 21102
Gamma-aminobutyric acid receptor subunit theta0202
Transporter0303
Cytochrome P450 2D10101
Cytochrome P450 2D260101
Cytochrome P450 2D30101
UDP-glucuronosyltransferase 2B70207
Kappa-type opioid receptor0101
Mu-type opioid receptor0101
Cytochrome P450 2D40101
Mas-related G-protein coupled receptor member X20022
endonuclease IV6006
PAX80001
67.9K protein110011
glucocerebrosidase8008
nuclear receptor subfamily 0 group B member 10101
atrial natriuretic peptide receptor 2 precursor1001
steroidogenic factor 10101
caspase-1 isoform alpha precursor3003
neuropeptide S receptor isoform A4004
Solute carrier family 22 member 30101
Tubulin alpha-1A chain0213
Tubulin beta chain0213
Plasma kallikrein0003
Tubulin beta-4A chain0326
Tubulin beta chain0326
Tubulin alpha-3C chain0326
Serine/threonine-protein kinase pim-10224
Tubulin alpha-1B chain0326
Tubulin alpha-4A chain0326
Tubulin beta-4B chain0326
Vesicular acetylcholine transporter0101
Tubulin beta-3 chain0326
Tubulin beta-2A chain0326
Tubulin polymerization-promoting protein0011
Tubulin beta-8 chain0326
Tubulin beta-2B chain0202
Tubulin alpha-3E chain0326
Tubulin alpha-1A chain0326
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
CREB-binding protein1001
Tubulin alpha-1C chain0326
Tubulin beta-6 chain0326
Tubulin beta-2B chain0326
Tubulin beta-1 chain0326
B2 bradykinin receptor0202
Dihydrofolate reductase0304
Dihydrofolate reductase0101
Chymotrypsinogen A0405
Beta-lactamase0103
Beta-galactosidase0102
Ectonucleotide pyrophosphatase/phosphodiesterase family member 20202
PH domain leucine-rich repeat-containing protein phosphatase 20101
Chymotrypsin-C0202
dopamine D1 receptor3003
regulator of G-protein signaling 4120012
Sex hormone-binding globulin0055
Corticosteroid-binding globulin0606
Potassium voltage-gated channel subfamily A member 10011
Multidrug and toxin extrusion protein 10404
Alkaline phosphatase, germ cell type0101
G protein-coupled receptor GPR350011
G-protein coupled receptor 350011
G-protein coupled receptor 350123
Glutathione S-transferase P0101
Alpha-tocopherol transfer protein0011
Beta-glucuronidase0101
Beta-glucuronidase0101
Glucose-6-phosphate 1-dehydrogenase0202
Alpha-synuclein3508
G-protein coupled bile acid receptor 10022
Glucose-6-phosphate 1-dehydrogenase 0101
NPC1-like intracellular cholesterol transporter 10011
Solute carrier organic anion transporter family member 1A50004
Multidrug resistance-associated protein 1 0203
Solute carrier organic anion transporter family member 1A10304
Solute carrier organic anion transporter family member 1A20104
Solute carrier organic anion transporter family member 1A30205
ATP-binding cassette sub-family C member 110001
Solute carrier organic anion transporter family member 1B30407
Solute carrier organic anion transporter family member 1A10001
Solute carrier organic anion transporter family member 1B20002
Solute carrier organic anion transporter family member 1B106010
Thymidine kinase 2 0101
Deoxycytidine kinase0014
Probable deoxycytidylate deaminase0001
Cytidine deaminase0002
AAA family ATPase 0002
AAA family ATPase 0001
Sterol O-acyltransferase 10101
Phenylethanolamine N-methyltransferase0101
Amine oxidase [flavin-containing] B0101
Amine oxidase [flavin-containing] A0404
Amine oxidase [flavin-containing] B0202
Amine oxidase [flavin-containing] B0202
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10112
Sigma non-opioid intracellular receptor 10011
P2Y purinoceptor 40011
Proto-oncogene tyrosine-protein kinase Src0213
P2Y purinoceptor 20011
P2X purinoceptor 10011
P2X purinoceptor 10011
P2X purinoceptor 30011
P2X purinoceptor 40011
P2Y purinoceptor 120101
P2X purinoceptor 20011
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 70001
Aldo-keto reductase family 1 member B100101
UDP-glucuronosyltransferase 1A90103
Prostaglandin G/H synthase 1 0405
Transient receptor potential cation channel subfamily A member 10022
Cytochrome c oxidase subunit 20202
Fatty acid-binding protein, liver0303
Albumin0358
Prostaglandin G/H synthase 10304
Interleukin-80202
Calcium/calmodulin-dependent protein kinase type II subunit alpha0101
Aldo-keto reductase family 1 member B10404
UDP-glucuronosyltransferase 1-60203
UDP-glucuronosyltransferase 1A1 0404
UDP-glucuronosyltransferase 1A40102
Prostaglandin G/H synthase 10404
Sodium- and chloride-dependent GABA transporter 10303
C-X-C chemokine receptor type 10202
Sodium- and chloride-dependent GABA transporter 20303
Sodium- and chloride-dependent GABA transporter 30303
Prostaglandin G/H synthase 209110
Prostaglandin G/H synthase 2 0303
UDP-glucuronosyltransferase 1A30001
UDP-glucuronosyltransferase 2B10 0101
Sodium- and chloride-dependent betaine transporter0303
Prostaglandin G/H synthase 20303
Prostaglandin G/H synthase 20203
Prostaglandin G/H synthase 1 0303
P2Y purinoceptor 120202
UDP-glucuronosyltransferase 1A70101
UDP-glucuronosyltransferase 1A100102
Solute carrier family 22 member 20002
Prostaglandin G/H synthase 2 0304
Thromboxane A2 receptor 0112
Prostaglandin E2 receptor EP1 subtype0325
Prostaglandin E2 receptor EP4 subtype0314
Prostaglandin F2-alpha receptor0202
Prostaglandin F2-alpha receptor0224
Prostaglandin E2 receptor EP3 subtype0325
Prostaglandin E2 receptor EP2 subtype0314
Prostaglandin F2-alpha receptor0011
Prostacyclin receptor0314
Solute carrier organic anion transporter family member 2A10103
Prostaglandin D2 receptor0101
Solute carrier family 22 member 70003
Solute carrier organic anion transporter family member 2A10305
Solute carrier organic anion transporter family member 2A10101
Solute carrier organic anion transporter family member 2B10101
Solute carrier family 22 member 70002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 19009
prostaglandin E2 receptor EP2 subtype1001
Prostaglandin E2 receptor EP3 subtype0202
Prostaglandin E2 receptor EP4 subtype0202
Prostaglandin E2 receptor EP1 subtype0202
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP2 subtype0202
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Solute carrier family 22 member 70001
Kinesin-like protein KIF110101
Nucleotide-binding oligomerization domain-containing protein 20101
Eyes absent homolog 20101
Angiotensin-converting enzyme 0202
Metallo-beta-lactamase VIM-130102
Beta-lactamase 0102
Beta-lactamase 0101
Beta-lactamase VIM-1 0102
Genome polyprotein 0112
chaperonin-containing TCP-1 beta subunit homolog1001
hypothetical protein, conserved4004
thyrotropin-releasing hormone receptor5005
relaxin receptor 1 isoform 11001
Flavin reductase (NADPH)0011
large T antigen0101
Estrogen receptor08110
Polyunsaturated fatty acid lipoxygenase ALOX150505
Lanosterol 14-alpha demethylase0033
Olfactory receptor 51E20134
nonstructural protein 14004
hexokinase-4 isoform 11001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor5005
glucokinase regulatory protein1001
Aromatase0606
17-beta-hydroxysteroid dehydrogenase type 10203
Cytochrome P450 1B10314
Estrogen receptor beta0315
Ghrelin O-acyltransferase0101
Sphingosine 1-phosphate receptor 10123
RCG53912, isoform CRA_a 0001
Sphingosine kinase 1 0001
Sphingosine kinase 20102
Sphingosine kinase 10102
Chain A, BCL-2-RELATED PROTEIN A10011
unnamed protein product0101
heat shock protein HSP 90-alpha isoform 20003
bcl-2-like protein 11 isoform 10011
Histone deacetylase 30303
Steroid 17-alpha-hydroxylase/17,20 lyase0404
Heme oxygenase 1 0202
Lanosterol 14-alpha demethylase0123
Cytochrome P450 11B1, mitochondrial0202
Cytochrome P450 11B2, mitochondrial0202
Heme oxygenase 20202
Malate dehydrogenase, cytoplasmic0303
Histone deacetylase 40303
Cytochrome P450 1440033
Steroid C26-monooxygenase0033
Steroid C26-monooxygenase0033
Mycocyclosin synthase0022
Lanosterol 14-alpha demethylase0011
Histone deacetylase 10303
Lanosterol 14-alpha demethylase0527
Sterol 14-alpha demethylase0022
Sterol 14-alpha demethylase0112
Histone deacetylase 70303
Histone deacetylase 20303
Polyamine deacetylase HDAC100303
Histone deacetylase 11 0303
14-alpha sterol demethylase 0022
Histone deacetylase 80303
Histone deacetylase 60303
Histone deacetylase 90303
Histone deacetylase 50303
heat shock protein 90, putative0003
likely tRNA 2'-phosphotransferase0101
lysosomal alpha-glucosidase preproprotein3003
Nuclear receptor subfamily 1 group I member 20066
Neuronal acetylcholine receptor subunit alpha-42103
Neuronal acetylcholine receptor subunit beta-22103
Nuclear receptor subfamily 1 group I member 20022
Chain A, Dihydrofolate reductase0011
glp-1 receptor, partial8008
Thymidylate synthase0202
Thymidylate synthase0101
Dihydrofolate reductase0011
Folylpolyglutamate synthase, mitochondrial0001
Folylpolyglutamate synthase, mitochondrial0001
Multidrug resistance associated protein0001
Voltage-dependent calcium channel subunit alpha-2/delta-10101
ClpP1001
Transitional endoplasmic reticulum ATPase0101
Chain A, DEOXYNUCLEOSIDE KINASE0101
Equilibrative nucleoside transporter 10101
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]1001
alpha synuclein, partial1001
luciferase2002
Caspase-72002
polyunsaturated fatty acid lipoxygenase ALOX123003
caspase-32002
histone deacetylase 9 isoform 35005
nuclear factor NF-kappa-B p105 subunit isoform 13003
Epidermal growth factor receptor0516
60 kDa chaperonin0202
60 kDa heat shock protein, mitochondrial0404
Acetylcholinesterase0303
Glutamate receptor ionotropic, kainate 11214
Glutamate receptor ionotropic, kainate 21214
Glutamate receptor ionotropic, kainate 31203
10 kDa heat shock protein, mitochondrial0404
Glutamate receptor ionotropic, kainate 41203
Thiosulfate sulfurtransferase0404
60 kDa chaperonin 0404
Glutamate receptor ionotropic, kainate 51203
10 kDa chaperonin 0404
Rho-associated protein kinase 20314
Rho-associated protein kinase 10314
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor3003
Metabotropic glutamate receptor 80202
Glutamate receptor ionotropic, NMDA 2D0101
Glutamate receptor ionotropic, NMDA 3B0101
Glutathione reductase, mitochondrial0505
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0134
ATP-citrate synthase 0101
Glutamate receptor 10213
Glutamate receptor 30213
Glutamate receptor 40213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Glutamate receptor ionotropic, NMDA 2B0101
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, kainate 50101
Glutamate racemase0001
Prolyl 4-hydroxylase0202
Glutamate receptor ionotropic, NMDA 3A0101
Alpha-ketoglutarate-dependent dioxygenase FTO0303
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10303
Proton-coupled amino acid transporter 10303
Serine racemase0101
Sodium- and chloride-dependent glycine transporter 20101
Ricin0101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Purine nucleoside phosphorylase 0012
Guanine deaminase0102
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
Glutamine synthetase0101
Neutral amino acid transporter A0202
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0202
Amino acid transporter0202
Vpr3003
Thymidine phosphorylase0001
Thymidine kinase0001
Beta-lactamase 0101
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Metallo-beta-lactamase VIM-11 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0101
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase SHV-10001
Beta-lactamase0001
Metallo-beta-lactamase type 20001
Beta-lactamase TEM0102
B2 metallo-beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-b-lactamase 0001
Beta-lactamase IMP-1 0001
BlaVIM-1 0001
Beta-lactamase 0001
Beta-lactamase 0001
Carbapenem-hydrolyzing beta-lactamase KPC0001
Beta-lactamase class B VIM-2 0001
Beta-lactamase 0001
Chain A, membrane-associated prostaglandin E synthase-20101
Parkin4004
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)4004
Prostaglandin-H2 D-isomerase0101
Prostaglandin E synthase0101
3',5'-cyclic-AMP phosphodiesterase 0202
Solute carrier organic anion transporter family member 2B1 0404
Phospholipase A2, major isoenzyme0202
Androgen receptor0314
Polyunsaturated fatty acid 5-lipoxygenase0304
Aldo-keto reductase family 1 member B10202
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Thromboxane-A synthase 0303
Indoleamine 2,3-dioxygenase 10202
Caspase-10203
Substance-P receptor0404
Bifunctional epoxide hydrolase 20202
Peroxisome proliferator-activated receptor gamma0055
Aldo-keto reductase family 1 member C30202
C-X-C chemokine receptor type 30101
Aldo-keto reductase family 1 member C2 0101
Prostaglandin D2 receptor 0202
Lactoylglutathione lyase0303
Aldo-keto reductase family 1 member C10101
Uracil nucleotide/cysteinyl leukotriene receptor0202
Rho-associated protein kinase 20202
Nicotinate phosphoribosyltransferase0101
Dehydrogenase/reductase SDR family member 90101
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
Ornithine decarboxylase0001
Retinoic acid receptor alpha0101
Retinoic acid receptor gamma0101
Retinoic acid receptor beta0101
Cellular retinoic acid-binding protein 20011
Mitogen-activated protein kinase 10112
Retinoic acid receptor RXR-alpha0101
Retinoic acid receptor RXR-beta0101
Retinoic acid receptor RXR-gamma0101
Cellular retinoic acid-binding protein 10101
Cellular retinoic acid-binding protein 10011
Estrogen receptor beta0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0202
Cytochrome P450 26A10101
Camphor 5-monooxygenase0001
Epoxide hydrolase 10002
Cytochrome P450 2C11 0101
Steroid 21-hydroxylase0101
Steroid 17-alpha-hydroxylase/17,20 lyase 0101
Cholesterol side-chain cleavage enzyme, mitochondrial 0101
Indoleamine 2,3-dioxygenase 10405
Cytochrome P450 2A20101
Cytochrome P450 11B1, mitochondrial 0101
Cytochrome P450 7A1 0101
Estrogen receptor0101
Gonadotropin-releasing hormone receptor0112
Type-1 angiotensin II receptor0101
Cytochrome P450 4F20101
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0202
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0101
Sodium/bile acid cotransporter0101
Cytochrome P450 7A10101
Lanosterol 14-alpha demethylase 0202
NPC intracellular cholesterol transporter 1 precursor1001
Caspase-30101
Caspase-40101
Caspase-50101
Caspase-90101
Cell division control protein 42 homolog0101
Ras-related C3 botulinum toxin substrate 10101
Serine/threonine-protein kinase PAK 10101
CAAX prenyl protease 2 isoform 20001
DNA gyrase subunit A0406
DNA primase0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Methyl-accepting chemotaxis protein NahY0011
Alpha-mannosidase 2C10101
Fucose-binding lectin PA-IIL0101
CD209 antigen0101
Acetylcholinesterase0101
Cytochrome P450 1A20101
Cytochrome P450 1A2 0101
Cannabinoid receptor 10202
Aromatase0011
Substance-P receptor0415
Adenosine receptor A10404
Type-2 angiotensin II receptor0202
Indoleamine 2,3-dioxygenase 20101
Calcium release-activated calcium channel protein 10101
methionyl-tRNA synthetase, putative0101
DNA gyrase subunit B0101
DNA gyrase subunit A0204
DNA gyrase subunit B0204
DNA topoisomerase 4 subunit A0101
DNA gyrase subunit B0101
DNA topoisomerase 2-alpha0113
Potassium voltage-gated channel subfamily E member 10101
DNA gyrase subunit A0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Potassium voltage-gated channel subfamily KQT member 10101
DNA gyrase subunit B0305
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial0101
STE240001
CAAX prenyl protease0001
Trypsin0001
Chain A, ARGINASE 10101
Chain A, Arginase 10101
Chain A, ARGINASE 10101
Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE0101
Chain A, Adenosine kinase, putative0101
Cystathionine gamma-lyase0101
Succinyl-diaminopimelate desuccinylase0202
Alpha-1B adrenergic receptor 0011
Beta-2 adrenergic receptor0213
POU domain, class 2, transcription factor 10001
Beta-1 adrenergic receptor0202
Alpha-1A adrenergic receptor0112
Alpha-1B adrenergic receptor0101
Alpha-1D adrenergic receptor0314
Alpha-2B adrenergic receptor0001
Alpha-1A adrenergic receptor0112
Alpha-1B adrenergic receptor0112
Alpha-2C adrenergic receptor0001
Alpha-2A adrenergic receptor0001
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
15-lipoxygenase, partial6006
Chain A, PROTEIN (CATECHOL OXIDASE)0101
Tyrosinase0101
Taste receptor type 2 member 380012
Muscarinic acetylcholine receptor DM10101
Cytochrome P450 2A130112
Neutrophil elastase0303
Complement C1s subcomponent0101
Nitric oxide synthase, endothelial0101
Collagenase 30202
Nitric oxide synthase, inducible0101
luciferase0001
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
Glutamate 5-kinase0001
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Pyridoxal kinase0012
Aldehyde oxidase0101
Monocarboxylate transporter 40001
Monocarboxylate transporter 20001
Monocarboxylate transporter 10102
C-terminal-binding protein 20101
Monocarboxylate transporter 20202
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0101
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0101
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0101
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0101
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0101
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0101
Chain A, APH(2')-Id0101
glucose-6-phosphate dehydrogenase0101
Nrf21001
signal transducer and activator of transcription 6, interleukin-4 induced1001
DNA polymerase III, partial1001
Neuraminidase 0202
hexokinase0101
galactokinase1001
interferon gamma precursor0001
tyrosine-protein kinase Yes1001
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
Maltase-glucoamylase, intestinal0101
NUAK family SNF1-like kinase 10101
Lysine-specific histone demethylase 1A0101
G2/mitotic-specific cyclin-B20101
Arginase 0101
Pancreatic triacylglycerol lipase0101
Prothrombin 0101
Urokinase-type plasminogen activator0202
Cationic trypsin0101
Chymotrypsin-like elastase family member 10101
Protein E60101
Neuraminidase0101
Interstitial collagenase0112
Phospholipase A20101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10202
Cytochrome P450 1A10213
Myeloperoxidase0202
Tyrosine-protein kinase Lck0112
Cyclin-dependent kinase 10112
Glycogen phosphorylase, liver form0112
Epoxide hydrolase 1 0101
Trypsin-10101
Trypsin-20101
Tyrosine-protein kinase Yes0112
Proto-oncogene tyrosine-protein kinase receptor Ret0112
Insulin-like growth factor 1 receptor0112
Seed linoleate 13S-lipoxygenase-10103
72 kDa type IV collagenase0101
Stromelysin-10202
Hepatocyte growth factor receptor0112
5-hydroxytryptamine receptor 1A0011
Heterogeneous nuclear ribonucleoprotein A10011
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI0101
Calmodulin-10101
Alpha-amylase 1A 0101
Lysosomal alpha-glucosidase0101
Sialidase0101
Malate dehydrogenase0101
Solute carrier family 2, facilitated glucose transporter member 20101
Cyclin-dependent kinase 40112
Cystic fibrosis transmembrane conductance regulator0011
Sucrase-isomaltase, intestinal0101
G2/mitotic-specific cyclin-B10101
Matrix metalloproteinase-90101
Urease subunit alpha0404
Serine/threonine-protein kinase B-raf0112
G2/mitotic-specific cyclin-B0101
Cytochrome P450 11B1, mitochondrial0101
Polyunsaturated fatty acid lipoxygenase ALOX150101
Chymotrypsinogen B0101
Tyrosine-protein phosphatase non-receptor type 10101
Polyunsaturated fatty acid lipoxygenase ALOX120101
Glycogen synthase kinase-3 beta0101
Solute carrier family 2, facilitated glucose transporter member 4 0101
Casein kinase II subunit alpha'0213
Amine oxidase [flavin-containing] A 0101
5'-nucleotidase0101
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal0101
G1/S-specific cyclin-D10101
Phosphatidylinositol 3-kinase regulatory subunit alpha0101
Proteasome subunit beta type-50101
Cytosol aminopeptidase0101
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 10101
Vasopressin V2 receptor0101
Tyrosine-protein kinase receptor UFO0101
RAC-alpha serine/threonine-protein kinase0112
Trypsin-30101
Vascular endothelial growth factor receptor 20101
Receptor-type tyrosine-protein kinase FLT30112
17-beta-hydroxysteroid dehydrogenase type 20101
Macrophage metalloelastase0101
Glutathione reductase0101
Tyrosine-protein kinase SYK0123
1-deoxy-D-xylulose 5-phosphate reductoisomerase0101
Prolyl endopeptidase0101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
Glycogen synthase kinase-3 alpha0112
Glycogen synthase kinase-3 beta0112
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10202
Serine/threonine-protein kinase Nek20112
Oligo-1,6-glucosidase IMA10101
Serine/threonine-protein kinase PLK10112
Death-associated protein kinase 10101
Mitogen-activated protein kinase 100112
Anthrax toxin receptor 20101
Casein kinase II subunit beta0202
Casein kinase II subunit alpha0202
Urease subunit beta0404
Lactoperoxidase0101
Aldo-keto reductase family 1 member B10101
Cyclin-dependent kinase 60112
Cyclin-dependent-like kinase 5 0112
Heat shock factor protein 10101
Sorbitol dehydrogenase0101
Cyclin homolog0101
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Dual specificity mitogen-activated protein kinase kinase 10112
Focal adhesion kinase 10112
Calcium/calmodulin-dependent protein kinase type II subunit beta0101
ELAV-like protein 30101
Cyclin-dependent kinase 5 activator 10101
ELAV-like protein 10101
Serine/threonine-protein kinase N10112
Probable maltase-glucoamylase 20101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Substance-K receptor0101
Integrase 0101
Casein kinase II subunit alpha 30202
Inositol polyphosphate multikinase0101
G2/mitotic-specific cyclin-B30101
Aldo-keto reductase family 1 member C210202
Enoyl-acyl-carrier protein reductase 0202
3-oxoacyl-acyl-carrier protein reductase 0101
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)0101
Cyclin-dependent kinase 10101
Phosphodiesterase 0101
Serine/threonine-protein kinase Nek60101
NADPH oxidase 40101
Dipeptidyl peptidase 30101
Inositol hexakisphosphate kinase 20101
Short transient receptor potential channel 50101
ALK tyrosine kinase receptor0101
Sialidase-20101
phosphoglycerate kinase1001
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Retinol-binding protein 40011
Beta-lactoglobulin0011
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain A, Breast cancer type 1 susceptibility protein1001
Chain H, Immunoglobulin Igg1 Heavy chain0011
Chain L, Immunoglobulin Igg1 Lambda Light Chain0011
Chain A, DODECIN0011
Chain A, DODECIN0011
Chain C, DODECIN0011
Chain E, DODECIN0011
NPYLR7B0011
Caspase-71001
DNA-directed RNA polymerase subunit beta0101
NH(3)-dependent NAD(+) synthetase0101
Arylacetamide deacetylase0102
Glutathione S-transferase omega-10101
Enoyl-[acyl-carrier-protein] reductase [NADH]0101
DNA-directed RNA polymerase subunit beta0101
Bone morphogenetic protein receptor type-1B0011
Cell division cycle 7-related protein kinase0011
Serine/threonine-protein kinase PLK40011
ATP-dependent RNA helicase DDX3X0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase Chk10011
Aurora kinase A0011
Cyclin-G-associated kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Receptor-interacting serine/threonine-protein kinase 20011
Mitotic checkpoint serine/threonine-protein kinase BUB10011
Dynamin-like 120 kDa protein, mitochondrial0011
Tyrosine-protein kinase JAK20011
Eukaryotic translation initiation factor 5B0011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50112
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Cyclin-dependent kinase-like 50011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30011
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
Tyrosine-protein kinase ABL10011
High affinity nerve growth factor receptor0011
ADP/ATP translocase 20011
Protein kinase C beta type0011
Insulin receptor0011
Eukaryotic translation initiation factor 4E0011
Tyrosine-protein kinase Fes/Fps0011
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Lyn0011
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0011
Tyrosine-protein kinase HCK0011
Platelet-derived growth factor receptor beta0011
Tyrosine-protein kinase Fgr0011
Serine/threonine-protein kinase A-Raf0011
Glycogen phosphorylase, brain form0011
Breakpoint cluster region protein0011
Fibroblast growth factor receptor 10011
ADP/ATP translocase 30011
Inosine-5'-monophosphate dehydrogenase 20011
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0011
cAMP-dependent protein kinase catalytic subunit alpha0112
General transcription and DNA repair factor IIH helicase subunit XPD0011
Ras-related protein Rab-6A0011
Ephrin type-A receptor 10011
Multifunctional protein ADE20011
cAMP-dependent protein kinase catalytic subunit beta0112
Ferrochelatase, mitochondrial0011
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10011
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Ephrin type-A receptor 20011
Ephrin type-B receptor 20011
Non-receptor tyrosine-protein kinase TYK20011
UMP-CMP kinase 0011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-beta serine/threonine-protein kinase0011
Dual specificity protein kinase TTK0011
DNA replication licensing factor MCM40011
Myosin-100011
Dual specificity mitogen-activated protein kinase kinase 20011
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
Serine/threonine-protein kinase receptor R30011
TGF-beta receptor type-20011
Electron transfer flavoprotein subunit beta0011
Tyrosine-protein kinase CSK0011
Glycine--tRNA ligase0011
Protein kinase C iota type0011
Exosome RNA helicase MTR40011
Tyrosine-protein kinase Tec0011
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0011
G protein-coupled receptor kinase 60011
26S proteasome regulatory subunit 6B0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 30011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0011
Casein kinase I isoform alpha0011
Casein kinase I isoform delta0011
MAP kinase-activated protein kinase 20011
Elongation factor Tu, mitochondrial0011
Choline-phosphate cytidylyltransferase A0011
Cysteine--tRNA ligase, cytoplasmic0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Dual specificity protein kinase CLK30011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Serine/threonine-protein kinase Nek30011
Dual specificity mitogen-activated protein kinase kinase 60011
LIM domain kinase 10011
LIM domain kinase 20011
Tyrosine--tRNA ligase, cytoplasmic0011
5'-AMP-activated protein kinase subunit gamma-10011
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Adenosine kinase0011
Ras-related protein Rab-100011
Actin-related protein 30011
Actin-related protein 20011
GTP-binding nuclear protein Ran0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0426
Peptidyl-prolyl cis-trans isomerase FKBP1B0022
Casein kinase I isoform gamma-20011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
ATP-dependent 6-phosphofructokinase, platelet type0011
DNA topoisomerase 2-beta0011
Protein kinase C theta type0011
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Protein kinase C zeta type0011
Protein kinase C delta type0011
Tyrosine-protein kinase BTK0011
Cyclin-dependent kinase 180011
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Mitogen-activated protein kinase kinase kinase kinase 20011
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40011
5'-AMP-activated protein kinase catalytic subunit alpha-10011
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
Integrin-linked protein kinase0011
Peptidyl-prolyl cis-trans isomerase FKBP50202
Non-receptor tyrosine-protein kinase TNK10011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60011
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Peroxisomal acyl-coenzyme A oxidase 10011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10011
Dual specificity testis-specific protein kinase 10011
Myosin light chain kinase, smooth muscle0011
Serine/threonine-protein kinase STK110011
Serine/threonine-protein kinase N20112
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Uncharacterized aarF domain-containing protein kinase 50011
Programmed cell death protein 40011
Putative heat shock protein HSP 90-beta 20011
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase N30011
Serine/threonine-protein kinase ULK30011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
ATP-dependent RNA helicase DHX300011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
Mitogen-activated protein kinase kinase kinase kinase 30011
MAP kinase-activated protein kinase 50011
Regulatory-associated protein of mTOR0101
Misshapen-like kinase 10011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
ATP-dependent RNA helicase DDX10011
Mitogen-activated protein kinase kinase kinase kinase 10011
MAP/microtubule affinity-regulating kinase 40011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase Nek10011
PAS domain-containing serine/threonine-protein kinase0011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
Dual specificity testis-specific protein kinase 20011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Target of rapamycin complex subunit LST80101
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase mTOR 0101
Phenylalanine--tRNA ligase beta subunit0011
Isoleucine--tRNA ligase, mitochondrial0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Mitogen-activated protein kinase kinase kinase 200011
Cyclin-dependent kinase 120011
Serine/threonine-protein kinase 260011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
5'-AMP-activated protein kinase subunit gamma-20011
Serine/threonine-protein kinase TBK10011
Septin-90011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase TAO20011
Serine/threonine-protein kinase ICK0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
Pyruvate kinase PKM0101
Sulfate anion transporter 10001
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
C-X-C chemokine receptor type 5 isoform 10101
ubiquitin-conjugating enzyme E2 N0101
C-C chemokine receptor type 60101
apelin receptor0101
bcl-2-related protein A10101
Endoglycoceramidase II 0001
Protein kinase C alpha type0101
Estrogen receptor0011
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
cAMP-dependent protein kinase catalytic subunit alpha 0101
Protein kinase C gamma type0101
Protein kinase C beta type0101
Estrogen receptor beta0011
Protein kinase C eta type0101
Protein kinase C theta type0101
Sphingosine 1-phosphate receptor 20112
Sphingosine 1-phosphate receptor 40112
Sphingosine 1-phosphate receptor 30112
Sphingosine 1-phosphate receptor 50112
Substance-P receptor0202
Neuromedin-K receptor0011
Substance-K receptor0112
Neuromedin-K receptor0112
Substance-K receptor0101
Substance-K receptor0101
Growth hormone secretagogue receptor type 10011
Transcription regulator protein BACH10101
Transcription factor MafK 0101
Macrophage migration inhibitory factor0101
NAD0001
Quinone oxidoreductase0003
Kelch-like ECH-associated protein 10123
Nuclear factor erythroid 2-related factor 20124
Nuclear factor erythroid 2-related factor 20001
NAD(P)H dehydrogenase [quinone] 10001
Kelch-like ECH-associated protein 10001
Cytochrome P450 3A50101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Splicing factor 3B subunit 30101
Potassium channel subfamily K member 30101
cGMP-gated cation channel alpha-10011
isocitrate dehydrogenase 1, partial1001
serine-protein kinase ATM isoform a1001
Alcohol dehydrogenase E chain0101
Alcohol dehydrogenase S chain0101
D(3) dopamine receptor0101
Urease subunit alpha0101
Urease subunit beta 0101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Chain X, Thyroid hormone receptor beta-10022
Chain X, Thyroid hormone receptor beta-10022
Proliferating cell nuclear antigen0202
Retinoic acid receptor RXR-alpha0022
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 4C10102
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
Beta-1 adrenergic receptor 0011
Beta-2 adrenergic receptor0011
Protein Rev 0011
5-hydroxytryptamine receptor 1B0101
Microtubule-associated protein tau0202
Chain A, PLASMINOGEN0011
Chain A, PLASMINOGEN0011
Plasminogen0213
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with trehalose0101
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with cellobiose0101
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with maltose0101
Trehalose-phosphatase0101
procathepsin L isoform 1 preproprotein0101
Delta0101
Cycloeucalenol cycloisomerase0101
Sterol-8,7-isomerase0101
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 4A10001
Solute carrier organic anion transporter family member 1C10101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Alkaline phosphatase, tissue-nonspecific isozyme0101
Intestinal-type alkaline phosphatase0101
Tryptophan 2,3-dioxygenase0102
SLC16A10 protein0002
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Monocarboxylate transporter 100002
Phospholipase A-2-activating protein0101
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Taste receptor type 2 member 140001
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Solute carrier family 2, facilitated glucose transporter member 90112
Cocaine esterase0101
Tissue factor0101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
D-alanyl-D-alanine dipeptidase0101
Sterol 14-alpha-demethylase0011
14-alpha sterol demethylase 0011
Cholesterol side-chain cleavage enzyme, mitochondrial 0011
14-alpha sterol demethylase 0011
Cholesterol 24-hydroxylase0213
Chain E, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain I, cAMP-dependent protein kinase inhibitor, alpha form0101
Chain B, Rho-associated protein kinase 10101
Chain A, Rho-associated protein kinase 10101
Chain A, Rho-associated protein kinase 10101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain I, cAMP-dependent protein kinase inhibitor alpha0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain I, cAMP-dependent protein kinase inhibitor alpha0101
Chain A, Rho-associated protein kinase 10101
cAMP-dependent protein kinase catalytic subunit alpha0101
cAMP-dependent protein kinase catalytic subunit alpha 0101
C-C motif chemokine 20101
cAMP-dependent protein kinase catalytic subunit gamma0101
Rho-associated protein kinase 20101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]