pimagedine has been researched along with Keratoconus in 1 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Keratoconus: A noninflammatory, usually bilateral protrusion of the cornea, the apex being displaced downward and nasally. It occurs most commonly in females at about puberty. The cause is unknown but hereditary factors may play a role. The -conus refers to the cone shape of the corneal protrusion. (From Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with pyridoxal hydrochloride resulted in significantly higher corneal stiffening after CXL." | 1.37 | The role of nonenzymatic glycation and carbonyls in collagen cross-linking for the treatment of keratoconus. ( Brummer, G; Conrad, GW; Littlechild, S; McCall, S; Zhang, Y, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brummer, G | 1 |
| Littlechild, S | 1 |
| McCall, S | 1 |
| Zhang, Y | 1 |
| Conrad, GW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Corneal Changes After Collagen Cross-linking ; Clinical and Oct Study[NCT05717517] | 100 participants (Anticipated) | Observational | 2023-08-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 other study available for pimagedine and Keratoconus
| Article | Year |
|---|---|
The role of nonenzymatic glycation and carbonyls in collagen cross-linking for the treatment of keratoconus.
Topics: Animals; Collagen Type I; Copper; Corneal Stroma; Cross-Linking Reagents; Dogfish; Electrophoresis, | 2011 |