Page last updated: 2024-10-20

pyridoxal and Keratoconus

pyridoxal has been researched along with Keratoconus in 1 studies

Keratoconus: A noninflammatory, usually bilateral protrusion of the cornea, the apex being displaced downward and nasally. It occurs most commonly in females at about puberty. The cause is unknown but hereditary factors may play a role. The -conus refers to the cone shape of the corneal protrusion. (From Dorland, 27th ed)

Research Excerpts

Excerpt	Relevance	Reference
"Pretreatment with pyridoxal hydrochloride resulted in significantly higher corneal stiffening after CXL."	1.37	The role of nonenzymatic glycation and carbonyls in collagen cross-linking for the treatment of keratoconus. ( Brummer, G; Conrad, GW; Littlechild, S; McCall, S; Zhang, Y, 2011)

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Brummer, G	1
Littlechild, S	1
McCall, S	1
Zhang, Y	1
Conrad, GW	1

Clinical Trials (1)

Trial Overview

Trial			Phase	Enrollment	Study Type	Start Date	Status
Corneal Changes After Collagen Cross-linking ; Clinical and Oct Study[NCT05717517]				100 participants (Anticipated)	Observational	2023-08-31	Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for pyridoxal and Keratoconus

Article	Year
The role of nonenzymatic glycation and carbonyls in collagen cross-linking for the treatment of keratoconus. Investigative ophthalmology & visual science, 2011, Aug-11, Volume: 52, Issue:9 Topics: Animals; Collagen Type I; Copper; Corneal Stroma; Cross-Linking Reagents; Dogfish; Electrophoresis,	2011