| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 1 | 0 | 0 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 1 | 0 | 0 | 1 |
| Chain A, Phospholipase A2 isoform 3 | 0 | 0 | 1 | 1 |
| Chain A, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain B, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | 1 | 0 | 0 | 1 |
| GTP-binding protein (rab7) | 0 | 0 | 1 | 1 |
| ras protein, partial | 0 | 0 | 1 | 1 |
| interleukin 8 | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 2 | 0 | 0 | 2 |
| GLS protein | 2 | 0 | 0 | 2 |
| AR protein | 2 | 0 | 0 | 2 |
| aldehyde dehydrogenase 1 family, member A1 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| hypothetical protein, conserved | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 2 | 0 | 0 | 2 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| glucocorticoid receptor [Homo sapiens] | 2 | 0 | 0 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | 2 | 0 | 0 | 2 |
| estrogen-related nuclear receptor alpha | 3 | 0 | 0 | 3 |
| estrogen nuclear receptor alpha | 3 | 0 | 0 | 3 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| glucocerebrosidase | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 1 | 0 | 0 | 1 |
| Rac1 protein | 0 | 0 | 1 | 1 |
| IDH1 | 1 | 0 | 0 | 1 |
| cell division cycle 42 (GTP binding protein, 25kDa), partial | 0 | 0 | 1 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 3 | 0 | 0 | 3 |
| Bloom syndrome protein isoform 1 | 3 | 0 | 0 | 3 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 2 | 0 | 0 | 2 |
| DNA polymerase iota isoform a (long) | 2 | 0 | 0 | 2 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 2 | 0 | 0 | 2 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| Prostaglandin-H2 D-isomerase | 0 | 1 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 2 | 0 | 2 |
| Multidrug resistance-associated protein 4 | 0 | 2 | 0 | 2 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 2 | 0 | 2 |
| Epidermal growth factor receptor | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 1 | 0 | 3 | 0 | 3 |
| Carbonic anhydrase 2 | 0 | 3 | 0 | 3 |
| Fatty acid-binding protein, liver | 0 | 1 | 0 | 1 |
| Integrin beta-3 | 0 | 1 | 0 | 1 |
| Myeloperoxidase | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Seed linoleate 13S-lipoxygenase-1 | 0 | 1 | 0 | 1 |
| Integrin alpha-IIb | 0 | 1 | 0 | 1 |
| Glutathione hydrolase 1 proenzyme | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 3 | 0 | 3 |
| Adenosine receptor A1 | 0 | 1 | 0 | 1 |
| Adenosine receptor A2a | 0 | 1 | 0 | 1 |
| Substance-P receptor | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 2 | 0 | 2 |
| Urotensin-2 receptor | 0 | 1 | 0 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial | 0 | 1 | 0 | 1 |
| Nuclear receptor ROR-gamma | 1 | 0 | 0 | 1 |
| Ras-related protein Rab-2A | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 2 | 1 | 5 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Rho-associated protein kinase 2 | 0 | 1 | 0 | 1 |
| Nicotinate phosphoribosyltransferase | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 20 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 2 | 0 | 2 |
| Sigma non-opioid intracellular receptor 1 | 0 | 0 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 0 | 1 | 1 |
| Potassium channel subfamily K member 3 | 0 | 1 | 0 | 1 |
| Potassium channel subfamily K member 3 | 0 | 1 | 0 | 1 |
| Potassium channel subfamily K member 2 | 0 | 0 | 1 | 1 |
| Potassium channel subfamily K member 9 | 0 | 1 | 0 | 1 |
| Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase | 0 | 1 | 0 | 1 |
| Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase | 0 | 1 | 0 | 1 |
| Glutamine synthetase | 0 | 1 | 0 | 1 |
| Cytochrome P450 71B1 | 0 | 1 | 0 | 2 |
| Glutamine synthetase | 0 | 1 | 0 | 1 |
| 2-dehydro-3-deoxyphosphooctonate aldolase | 0 | 1 | 0 | 1 |
| ATAD5 protein, partial | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | 1 | 0 | 0 | 1 |
| geminin | 2 | 0 | 0 | 2 |
| Spike glycoprotein | 1 | 0 | 0 | 1 |
| Chain A, Ferritin light chain | 1 | 0 | 0 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| GLI family zinc finger 3 | 2 | 0 | 0 | 2 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 2 | 0 | 0 | 2 |
| progesterone receptor | 2 | 0 | 0 | 2 |
| farnesoid X nuclear receptor | 1 | 0 | 0 | 1 |
| pregnane X nuclear receptor | 2 | 0 | 0 | 2 |
| G | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 2 | 0 | 0 | 2 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| Histone H2A.x | 1 | 0 | 0 | 1 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 1 | 0 | 0 | 1 |
| heat shock protein beta-1 | 2 | 0 | 0 | 2 |
| cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
| lamin isoform A-delta10 | 2 | 0 | 0 | 2 |
| Fatty-acid amide hydrolase 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 2 | 1 | 1 | 4 |
| UDP-glucuronosyltransferase 1A9 | 0 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 4 | 0 | 2 | 0 | 2 |
| Interferon beta | 2 | 0 | 0 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
| Cellular tumor antigen p53 | 1 | 0 | 0 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 0 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 1 | 1 | 4 |
| Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
| Sodium- and chloride-dependent GABA transporter 1 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 0 | 0 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 0 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 0 | 0 | 1 | 1 |
| Sodium- and chloride-dependent betaine transporter | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 1 | 1 | 4 |
| Fatty-acid amide hydrolase 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 0 | 0 | 1 | 1 |
| GABA theta subunit | 2 | 1 | 1 | 4 |
| Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 2 | 1 | 1 | 4 |
| UDP-glucuronosyltransferase 1A8 | 0 | 0 | 0 | 1 |
| cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 | 1 | 0 | 0 | 1 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 1 | 0 | 0 | 1 |
| SMAD family member 2 | 1 | 0 | 0 | 1 |
| NFKB1 protein, partial | 1 | 0 | 0 | 1 |
| SMAD family member 3 | 1 | 0 | 0 | 1 |
| thioredoxin glutathione reductase | 1 | 0 | 0 | 1 |
| Smad3 | 1 | 0 | 0 | 1 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| procathepsin L isoform 1 preproprotein | 0 | 1 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 1 | 0 | 0 | 1 |
| muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
| Glucocorticoid receptor | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-1 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| Glycine receptor subunit beta | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-2 | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-3 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 1 | 0 | 0 | 1 |
| Ataxin-2 | 1 | 0 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |