Page last updated: 2024-09-27

Akinetic Autism

A syndrome characterized by a silent and inert state without voluntary motor activity despite preserved sensorimotor pathways and vigilance. Bilateral FRONTAL LOBE dysfunction involving the anterior cingulate gyrus and related brain injuries are associated with this condition. This may result in impaired abilities to communicate and initiate motor activities. (From Adams et al., Principles of Neurology, 6th ed, p348; Fortschr Neurol Psychiatr 1995 Feb;63(2):59-67)

Synonyms(5)

Synonym
Mutism, Akinetic
Coma Vigil
Akinetic Autism
Akinetic Mutism
Coma Vigilans

Research Excerpts

Overview

ExcerptReference
"Akinetic mutism is a wakeful state of severe apathy and paucity of volitional movement."( Callender, DM; Casella, DP; Dhadwal, N; Spiegel, DR, 2008)
"Akinetic mutism is a rare, complex neuropathologic disorder."( An, YS; Kim, YW; Shin, JC, 2010)
"Akinetic mutism is considered as an alteration of the motivational state of the person, which the patient is unable to initiate verbal or motor responses voluntary, even with preserved sensorimotor and surveillance functions."( Arevalo-Saenz, A; Pedrosa-Sanchez, M; Sola, RG, 2017)
"Typically, akinetic mutism is described as a transient surgeries posterior fossa."( Arevalo-Saenz, A; Pedrosa-Sanchez, M; Sola, RG, 2017)

Treatment

ExcerptReference
"In a patient with akinetic mutism, extensive circumscribed bilateral lesions in the precentral part of the centrum semiovale, due to delayed necrotizing leucoencephalopathy after combined intravenous polychemotherapy and radiation, were found at autopsy."( Gütling, E; Kleihues, P; Landis, T, 1992)
"There are reports of successful treatment of akinetic mutism, the most severe form of abulia, with bromocriptine."( Barrett, K, 1991)
"The patient developed a syndrome of akinetic mutism that improved after administration of bromocriptine and metoprolol."( Brückmann, H; Freyberger, HJ; Kömpf, D; Moser, A, 1995)
"Postoperatively, the patient developed akinetic mutism, but her condition improved after administration of bromocriptine."( Kim, MS; Kwon, SJ; Lee, CH; Lee, SJ; Rhee, JJ, 2007)
"The pharmaceutical treatment of akinetic mutism typically includes dopaminergic agents, but the resulting therapeutic effects are often unsatisfactory, and it remains unclear whether late treatment using these medications is effective."( An, YS; Kim, YW; Shin, JC, 2010)
"In general, patients reach an akinetic mutism state within a few months of disease onset and die soon after if supportive therapies are not administered."( Akagi, A; Ito, M; Iwasaki, Y; Kawai, Y; Kitamoto, T; Kobayashi, A; Miyahara, H; Mori, K; Riku, Y; Yoshida, M, 2021)

Research

Studies (99)

TimeframeStudies, This Condition (%)All Conditions %
pre-199036 (36.36)23.3326
1990's17 (17.17)12.5806
2000's22 (22.22)18.1394
2010's15 (15.15)28.8240
2020's9 (9.09)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0low10
choline0low20
lactic acid0low10
glycine0low10
hydrogen0low10
dihydroxyphenylalanine0low10
pyridoxine0low10
3-methoxytyrosine0low10
phenytoin0low10
amantadine0low10
amoxapine0low10
azathioprine0low10
baclofen0low20
benserazide0low10
droperidol0low10
fluphenazine0low10
fluorouracil0low10
fluoxetine0low10
glyphosate0low10
hydroxychloroquine0low10
methadone0low10
methylphenidate0low20
metoprolol0low10
apnea0low10
tegafur0low10
trihexyphenidyl0low20
zolpidem0low20
prednisolone0low10
aspartic acid0low10
physostigmine0low10
apomorphine0low10
levodopa0low130
tyrosine0low10
methionine0low20
mannitol0low10
propane0low10
methylprednisolone0low50
butane0low10
sarin0low10
thiophenes0low10
potassium cyanide0low10
ephedrine0low20
lithium carbonate0low10
chromonar0low10
cytidine diphosphate choline0low10
pyrithioxin0medium11
vidarabine0low10
xenon0low20
magnesium sulfate0low10
lisuride0low10
bromocriptine0low150
pergolide0low10
fomesafen0low100
atomoxetine hydrochloride0low10
n 0437, (-)-isomer0low10
n-acetylaspartic acid0low10
fluorodeoxyglucose f180low50
lopinavir0low10
deoxyglucose0low10
ro 8-05760low10
methotrexate0low30
ritonavir0low10
tacrolimus0low30
cocaine0low10
benztropine0low10
myelin basic protein0low10
amphotericin b0low10
hydromorphone0low10
morphine0low10
cysteine0low10
heroin0low10
ergoline0low10
technetium tc 99m exametazime0low30
mefloquine0low20
s-adenosylmethionine0low10
galactocerebroside0low10
interleukin-80low10
cyclosporine0low10
sapropterin0low10
olanzapine0low10
5-methyltetrahydrofolate0low10
eye0low10
carbidopa0low30
technetium tc 99m bicisate0low10

Protein Targets (1,103)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
acetylcholinesterase100010
thioredoxin reductase170017
RAR-related orphan receptor gamma120012
NFKB1 protein, partial4004
GLI family zinc finger 3200020
AR protein290029
signal transducer and activator of transcription 6, interleukin-4 induced1001
thyroid stimulating hormone receptor4004
regulator of G-protein signaling 4120012
EWS/FLI fusion protein120012
estrogen nuclear receptor alpha250025
putative alpha-glucosidase1001
euchromatic histone-lysine N-methyltransferase 2200020
thyroid hormone receptor beta isoform 2190019
heat shock protein beta-13003
peripheral myelin protein 22180018
histone acetyltransferase KAT2A isoform 17007
lamin isoform A-delta10210021
Solute carrier family 22 member 20204
Solute carrier family 22 member 1 0509
Glutamate receptor ionotropic, NMDA 2D0101
Glutamate receptor ionotropic, NMDA 3B0101
Matrix protein 20112
Matrix protein 20123
Glutamate receptor ionotropic, NMDA 1 0518
Spike glycoprotein111416
Glutamate receptor ionotropic, NMDA 2A 0518
Glutamate receptor ionotropic, NMDA 2B0518
Glutamate receptor ionotropic, NMDA 2C0518
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, NMDA 2B0101
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 2D0518
Solute carrier family 22 member 10304
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0518
Multidrug and toxin extrusion protein 10202
Solute carrier family 22 member 20304
Glutamate receptor ionotropic, NMDA 3A0518
ATP-dependent phosphofructokinase130013
Chain A, TYROSYL-DNA PHOSPHODIESTERASE7007
Chain A, Beta-lactamase4004
Chain A, 2-oxoglutarate Oxygenase9009
Chain A, Ferritin light chain7007
endonuclease IV4004
hypoxia-inducible factor 1 alpha subunit8008
Fumarate hydratase6006
USP1 protein, partial9009
GLS protein130013
TDP1 protein260026
Thrombopoietin3003
aldehyde dehydrogenase 1 family, member A1110011
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
nuclear receptor subfamily 1, group I, member 3120012
progesterone receptor130013
isocitrate dehydrogenase 1, partial1001
cytochrome P450 family 3 subfamily A polypeptide 4140014
glucocorticoid receptor [Homo sapiens]170017
retinoic acid nuclear receptor alpha variant 1130013
estrogen-related nuclear receptor alpha210021
cytochrome P450 2D6120012
polyprotein6006
67.9K protein9009
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a170017
activating transcription factor 66006
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
v-jun sarcoma virus 17 oncogene homolog (avian)110011
cytochrome P450 2D6 isoform 14004
peripheral myelin protein 22 isoform 14004
cellular tumor antigen p53 isoform a6006
D(1A) dopamine receptor9009
atrial natriuretic peptide receptor 1 precursor4004
vitamin D3 receptor isoform VDRA100010
chromobox protein homolog 1130013
thyroid hormone receptor beta isoform a3003
potassium voltage-gated channel subfamily H member 2 isoform d110011
atrial natriuretic peptide receptor 2 precursor3003
ubiquitin carboxyl-terminal hydrolase 2 isoform a4004
serine/threonine-protein kinase mTOR isoform 16006
nuclear factor erythroid 2-related factor 2 isoform 1160016
geminin220022
survival motor neuron protein isoform d5005
cytochrome P450 3A4 isoform 18008
M-phase phosphoprotein 87007
transient receptor potential cation channel subfamily V member 11001
muscarinic acetylcholine receptor M16006
neuropeptide S receptor isoform A4004
Gamma-aminobutyric acid receptor subunit pi85114
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
ATP-binding cassette sub-family C member 3018018
Multidrug resistance-associated protein 4018019
5-hydroxytryptamine receptor 4018018
Bile salt export pump026026
Cellular tumor antigen p53190019
Aldo-keto reductase family 1 member B10808
Muscarinic acetylcholine receptor M2011011
Muscarinic acetylcholine receptor M4013013
5-hydroxytryptamine receptor 1A0628
Muscarinic acetylcholine receptor M5013013
Alpha-2A adrenergic receptor018119
Cytochrome P450 2D60909
Muscarinic acetylcholine receptor M1012113
D(2) dopamine receptor018626
Gamma-aminobutyric acid receptor subunit beta-185114
Alpha-2B adrenergic receptor019019
Gamma-aminobutyric acid receptor subunit delta85114
Gamma-aminobutyric acid receptor subunit gamma-285316
Alpha-2C adrenergic receptor017017
Gamma-aminobutyric acid receptor subunit alpha-585114
Gamma-aminobutyric acid receptor subunit alpha-385114
Muscarinic acetylcholine receptor M3013013
D(1A) dopamine receptor016321
D(4) dopamine receptor09212
Gamma-aminobutyric acid receptor subunit gamma-185114
Gamma-aminobutyric acid receptor subunit alpha-285114
Sodium-dependent noradrenaline transporter 014115
Alpha-1D adrenergic receptor018018
5-hydroxytryptamine receptor 2A019322
5-hydroxytryptamine receptor 2C018321
Gamma-aminobutyric acid receptor subunit alpha-485114
Gamma-aminobutyric acid receptor subunit gamma-385114
Gamma-aminobutyric acid receptor subunit alpha-685114
Sodium-dependent serotonin transporter013215
5-hydroxytryptamine receptor 70202
Histamine H1 receptor012113
D(3) dopamine receptor020122
5-hydroxytryptamine receptor 2B016016
Histamine H2 receptor5005
D(1A) dopamine receptor4004
Sulfotransferase 1A10101
5-hydroxytryptamine receptor 6016016
Gamma-aminobutyric acid receptor subunit alpha-185316
Gamma-aminobutyric acid receptor subunit beta-385114
Gamma-aminobutyric acid receptor subunit beta-285316
Disintegrin and metalloproteinase domain-containing protein 173003
Inositol monophosphatase 15005
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Sulfotransferase 2A10101
TAR DNA-binding protein 435005
GABA theta subunit85114
Canalicular multispecific organic anion transporter 1018018
Ataxin-2160016
Gamma-aminobutyric acid receptor subunit epsilon85114
Histamine H4 receptor0101
Chain A, HADH2 protein7007
Chain B, HADH2 protein7007
Chain A, Cruzipain2002
interleukin 84004
phosphopantetheinyl transferase9009
farnesoid X nuclear receptor7007
peroxisome proliferator-activated receptor delta110011
vitamin D (1,25- dihydroxyvitamin D3) receptor9009
tumor necrosis factor1001
Cytochrome P450 1A20303
Cytochrome P450 3A4011113
Cytochrome P450 2C9 0707
Cytochrome P450 2C190404
Nuclear receptor ROR-gamma3003
Potassium voltage-gated channel subfamily H member 2018018
Aurora kinase B0123
Broad substrate specificity ATP-binding cassette transporter ABCG20506
ATAD5 protein, partial8008
Microtubule-associated protein tau120012
arylsulfatase A110011
Bloom syndrome protein isoform 1100010
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
Luciferase6006
estrogen receptor 2 (ER beta)120012
peroxisome proliferator activated receptor gamma120012
aryl hydrocarbon receptor9009
thyroid stimulating hormone receptor6006
Histone H2A.x6006
cytochrome P450 2C19 precursor2002
cytochrome P450 2C9 precursor3003
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 15005
mitogen-activated protein kinase 16006
nuclear receptor ROR-gamma isoform 19009
lethal factor (plasmid)4004
Voltage-dependent calcium channel gamma-2 subunit9009
Integrin beta-34004
Integrin alpha-IIb4004
5-hydroxytryptamine receptor 2C09010
Tryptophan 5-hydroxylase 10202
5-hydroxytryptamine receptor 2A0909
Alpha-1B adrenergic receptor0909
D0606
D(3) dopamine receptor0404
5-hydroxytryptamine receptor 1A015116
Alpha-2B adrenergic receptor0606
Glutamate receptor 2100010
D(2) dopamine receptor0404
D(1B) dopamine receptor0304
Alpha-2C adrenergic receptor0606
Alpha-2A adrenergic receptor0606
Alpha-1D adrenergic receptor0707
D(1B) dopamine receptor0303
5-hydroxytryptamine receptor 1B012012
5-hydroxytryptamine receptor 1D0303
D(4) dopamine receptor0415
5-hydroxytryptamine receptor 1F0303
5-hydroxytryptamine receptor 2B0808
5-hydroxytryptamine receptor 60303
5-hydroxytryptamine receptor 7 0404
5-hydroxytryptamine receptor 5A0303
5-hydroxytryptamine receptor 5B0303
5-hydroxytryptamine receptor 3A0303
Alpha-1A adrenergic receptor0909
5-hydroxytryptamine receptor 70303
D(2) dopamine receptor09514
E3 ubiquitin-protein ligase Mdm20101
D0101
5-hydroxytryptamine receptor 4 0303
D0404
ATPase family AAA domain-containing protein 5120012
Sigma non-opioid intracellular receptor 1014014
5-hydroxytryptamine receptor 3B0303
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE8008
Metabotropic glutamate receptor 60011
Excitatory amino acid transporter 40101
Glutamate transporter homolog0011
Carbonic anhydrase 10003
Carbonic anhydrase 20014
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
5-hydroxytryptamine receptor 1D0001
Excitatory amino acid transporter 10101
Excitatory amino acid transporter 20101
Excitatory amino acid transporter 30101
Metabotropic glutamate receptor 10011
Metabotropic glutamate receptor 20011
Carbonic anhydrase-like protein, putative0003
Carbonic anhydrase 40001
glp-1 receptor, partial3003
IDH16006
SMAD family member 24004
SMAD family member 34004
thioredoxin glutathione reductase1001
retinoid X nuclear receptor alpha9009
pregnane X nuclear receptor140014
G8008
P531001
hemoglobin subunit beta2002
DNA polymerase iota isoform a (long)3003
muscleblind-like protein 1 isoform 14004
Bile salt export pump0404
Interferon beta100010
HLA class I histocompatibility antigen, B alpha chain 8008
Inositol hexakisphosphate kinase 18008
Protein-arginine deiminase type-40202
cytochrome P450 2C9, partial8008
Gamma-aminobutyric acid type B receptor subunit 20224
Gamma-aminobutyric acid type B receptor subunit 20303
Gamma-aminobutyric acid type B receptor subunit 10224
Gamma-aminobutyric acid type B receptor subunit 10202
Zinc finger protein mex-50011
POsterior Segregation0011
Genome polyprotein0101
Replicase polyprotein 1ab06410
Hexokinase-20101
Spike glycoprotein0145
Replicase polyprotein 1ab0145
Transmembrane protease serine 20145
Procathepsin L0145
Muscarinic acetylcholine receptor M10404
Replicase polyprotein 1a0145
Replicase polyprotein 1ab0145
Replicase polyprotein 1ab0347
Muscarinic acetylcholine receptor M20404
Sodium-dependent dopamine transporter0617
Histamine H2 receptor0606
Sodium-dependent serotonin transporter0607
Sodium-dependent dopamine transporter 010111
Angiotensin-converting enzyme 2 0145
Genome polyprotein 0213
dopamine D1 receptor4004
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
ATP-dependent translocase ABCB10303
ATP-dependent translocase ABCB1010013
Beta-1 adrenergic receptor0617
Androgen receptor0606
ATP-dependent translocase ABCB10303
Alpha-synuclein1203
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10102
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-30326
Neuronal acetylcholine receptor subunit alpha-40326
Neuronal acetylcholine receptor subunit alpha-20326
Neuronal acetylcholine receptor subunit beta-20326
Neuronal acetylcholine receptor subunit beta-30326
Neuronal acetylcholine receptor subunit beta-40326
Neuronal acetylcholine receptor subunit alpha-50326
Acetylcholinesterase0304
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0001
Neuronal acetylcholine receptor subunit alpha-60326
Neuronal acetylcholine receptor subunit alpha-90326
Neuronal acetylcholine receptor subunit alpha-70427
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100326
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0404
Gamma-aminobutyric acid receptor subunit delta0404
Amyloid-beta precursor protein1102
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
Gamma-aminobutyric acid receptor subunit alpha-10527
Gamma-aminobutyric acid receptor subunit beta-10516
Gamma-aminobutyric acid receptor subunit gamma-20527
Liver carboxylesterase 10002
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0202
Gamma-aminobutyric acid receptor subunit beta-30516
Gamma-aminobutyric acid receptor subunit alpha-50527
Gamma-aminobutyric acid receptor subunit alpha-30527
Lysosomal Pro-X carboxypeptidase0101
Gamma-aminobutyric acid receptor subunit alpha-20527
Gamma-aminobutyric acid receptor subunit beta-20527
Gamma-aminobutyric acid receptor subunit alpha-40516
Gamma-aminobutyric acid receptor subunit epsilon0404
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
Leukotriene B4 receptor 10101
Gamma-aminobutyric acid receptor subunit alpha-60516
Sodium-dependent dopamine transporter0303
Gamma-aminobutyric acid receptor subunit gamma-10404
Gamma-aminobutyric acid receptor subunit gamma-30404
Leukotriene B4 receptor 20101
Gamma-aminobutyric acid receptor subunit theta0404
Transporter0517
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
15-lipoxygenase, partial3003
polyunsaturated fatty acid lipoxygenase ALOX122002
runt-related transcription factor 1 isoform AML1b1001
core-binding factor subunit beta isoform 21001
DNA polymerase kappa isoform 16006
Epidermal growth factor receptor0426
Glutamate receptor 11001
Glutamate receptor 31001
Glutamate receptor 41001
Caspase-72002
DNA polymerase beta2002
Voltage-dependent L-type calcium channel subunit alpha-1F0303
Angiotensin-converting enzyme0707
N-acetyltransferase Eis0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Nuclear receptor subfamily 3 group C member 3 0707
Bone morphogenetic protein receptor type-1B0022
Cell division cycle 7-related protein kinase0022
Serine/threonine-protein kinase PLK40022
ATP-dependent RNA helicase DDX3X0022
Pyridoxal kinase0023
Citron Rho-interacting kinase0022
Serine/threonine-protein kinase Chk10022
Aurora kinase A0022
Cyclin-G-associated kinase0022
Ephrin type-B receptor 60022
Peroxisomal acyl-coenzyme A oxidase 30022
Receptor-interacting serine/threonine-protein kinase 20022
Mitotic checkpoint serine/threonine-protein kinase BUB10022
Dynamin-like 120 kDa protein, mitochondrial0022
Eukaryotic translation initiation factor 5B0022
Rho-associated protein kinase 20022
Serine/threonine-protein kinase ULK10022
Serine/threonine-protein kinase/endoribonuclease IRE10022
Ribosomal protein S6 kinase alpha-50022
U5 small nuclear ribonucleoprotein 200 kDa helicase0022
Ribosomal protein S6 kinase alpha-40022
Serine/threonine-protein kinase 160022
Serine/threonine-protein kinase 100022
Serine/threonine-protein kinase D30022
Structural maintenance of chromosomes protein 20022
Mitogen-activated protein kinase kinase kinase 60022
Mitogen-activated protein kinase kinase kinase kinase 40022
Serine/threonine-protein kinase LATS10022
Serine/threonine-protein kinase PAK 40022
Tyrosine-protein kinase ABL10033
High affinity nerve growth factor receptor0022
Guanine nucleotide-binding protein G(i) subunit alpha-20011
ADP/ATP translocase 20022
Protein kinase C beta type0022
Insulin receptor0022
Tyrosine-protein kinase Lck0123
Tyrosine-protein kinase Fyn0224
Cyclin-dependent kinase 10022
Glycogen phosphorylase, liver form0022
Tyrosine-protein kinase Fes/Fps0022
Adenine phosphoribosyltransferase0022
Tyrosine-protein kinase Yes0022
Tyrosine-protein kinase Lyn0022
Proto-oncogene tyrosine-protein kinase receptor Ret0022
Insulin-like growth factor 1 receptor0022
Signal recognition particle receptor subunit alpha0022
Cytochrome c1, heme protein, mitochondrial0022
Hepatocyte growth factor receptor0022
Tyrosine-protein kinase HCK0022
Platelet-derived growth factor receptor beta0022
Tyrosine-protein kinase Fgr0022
Serine/threonine-protein kinase A-Raf0022
Glycogen phosphorylase, brain form0022
Breakpoint cluster region protein0022
Serine/threonine-protein kinase pim-10022
Fibroblast growth factor receptor 10022
DNA topoisomerase 2-alpha0022
Cyclin-dependent kinase 40022
ADP/ATP translocase 30022
Inosine-5'-monophosphate dehydrogenase 20022
Proto-oncogene tyrosine-protein kinase Src0022
cAMP-dependent protein kinase type II-alpha regulatory subunit0022
Serine/threonine-protein kinase B-raf0022
Potassium voltage-gated channel subfamily E member 10101
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0022
Ribosyldihydronicotinamide dehydrogenase [quinone]0022
Tyrosine-protein kinase Fer0022
Protein kinase C alpha type0022
cAMP-dependent protein kinase catalytic subunit alpha0022
General transcription and DNA repair factor IIH helicase subunit XPD0022
Casein kinase II subunit alpha'0022
Ras-related protein Rab-6A0022
Ephrin type-A receptor 10022
Multifunctional protein ADE20022
cAMP-dependent protein kinase catalytic subunit gamma0011
cAMP-dependent protein kinase catalytic subunit beta0022
Ferrochelatase, mitochondrial0022
Ribosomal protein S6 kinase beta-10022
Tyrosine-protein kinase JAK10022
Cyclin-dependent kinase 20033
Beta-adrenergic receptor kinase 10022
Probable ATP-dependent RNA helicase DDX60022
Mitogen-activated protein kinase 3 0022
MAP/microtubule affinity-regulating kinase 30022
Deoxycytidine kinase0022
Mitogen-activated protein kinase 10022
Ephrin type-A receptor 20022
Ephrin type-B receptor 20022
Non-receptor tyrosine-protein kinase TYK20022
UMP-CMP kinase 0022
Phosphatidylethanolamine-binding protein 10022
Wee1-like protein kinase0022
Heme oxygenase 20022
S-adenosylmethionine synthase isoform type-20022
DnaJ homolog subfamily A member 10022
RAC-alpha serine/threonine-protein kinase0022
RAC-beta serine/threonine-protein kinase0022
Dual specificity protein kinase TTK0022
DNA replication licensing factor MCM40022
Myosin-100022
Dual specificity mitogen-activated protein kinase kinase 20022
Receptor-type tyrosine-protein kinase FLT30022
Bone morphogenetic protein receptor type-1A0022
Activin receptor type-1B0022
TGF-beta receptor type-10022
TGF-beta receptor type-20022
Electron transfer flavoprotein subunit beta0022
Tyrosine-protein kinase CSK0022
Glycine--tRNA ligase0022
Protein kinase C iota type0022
Exosome RNA helicase MTR40022
Serine/threonine-protein kinase mTOR0325
Tyrosine-protein kinase Tec0022
Tyrosine-protein kinase ABL20022
Tyrosine-protein kinase FRK0022
G protein-coupled receptor kinase 60022
Tyrosine-protein kinase SYK0022
26S proteasome regulatory subunit 6B0022
Mitogen-activated protein kinase 80022
Mitogen-activated protein kinase 90022
Dual specificity mitogen-activated protein kinase kinase 30022
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0022
Casein kinase I isoform alpha0022
Casein kinase I isoform delta0022
MAP kinase-activated protein kinase 20022
Elongation factor Tu, mitochondrial0022
Choline-phosphate cytidylyltransferase A0022
Cysteine--tRNA ligase, cytoplasmic0022
Casein kinase I isoform epsilon0022
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0022
Dual specificity protein kinase CLK10022
Dual specificity protein kinase CLK20022
Dual specificity protein kinase CLK30022
Glycogen synthase kinase-3 alpha0022
Glycogen synthase kinase-3 beta0022
Cyclin-dependent kinase 70022
Cyclin-dependent kinase 90022
Ras-related protein Rab-27A0022
Interleukin-1 receptor-associated kinase 10022
Potassium voltage-gated channel subfamily KQT member 10101
Ribosomal protein S6 kinase alpha-30022
Serine/threonine-protein kinase Nek20022
Serine/threonine-protein kinase Nek30022
Dual specificity mitogen-activated protein kinase kinase 60022
Serine/threonine-protein kinase PLK10022
LIM domain kinase 10022
LIM domain kinase 20022
Mitogen-activated protein kinase 100022
Tyrosine--tRNA ligase, cytoplasmic0022
5'-AMP-activated protein kinase subunit gamma-10022
Ephrin type-B receptor 30022
Ephrin type-A receptor 50022
Ephrin type-B receptor 40022
Ephrin type-A receptor 40022
Adenylate kinase 2, mitochondrial0022
Adenosine kinase0022
Ras-related protein Rab-100022
Actin-related protein 30022
Actin-related protein 20022
GTP-binding nuclear protein Ran0022
Casein kinase I isoform gamma-20022
Cyclin-dependent kinase 30011
Cyclin-dependent kinase 60022
Cyclin-dependent-like kinase 5 0022
Cyclin-dependent kinase 160022
Cyclin-dependent kinase 170022
ATP-dependent 6-phosphofructokinase, platelet type0022
Dual specificity mitogen-activated protein kinase kinase 10022
DNA topoisomerase 2-beta0022
Protein kinase C theta type0022
Activin receptor type-10022
Macrophage-stimulating protein receptor0022
Focal adhesion kinase 10022
Protein kinase C delta type0022
Tyrosine-protein kinase BTK0022
Activated CDC42 kinase 10022
Epithelial discoidin domain-containing receptor 10022
Mitogen-activated protein kinase kinase kinase kinase 20022
Serine/threonine-protein kinase 40022
5'-AMP-activated protein kinase catalytic subunit alpha-10022
Dual specificity mitogen-activated protein kinase kinase 50022
Mitogen-activated protein kinase 70022
Serine/threonine-protein kinase PAK 20022
Serine/threonine-protein kinase 30022
Mitogen-activated protein kinase kinase kinase 10022
Integrin-linked protein kinase0022
Rho-associated protein kinase 10022
Non-receptor tyrosine-protein kinase TNK10022
Calcium/calmodulin-dependent protein kinase type II subunit gamma0022
Calcium/calmodulin-dependent protein kinase type II subunit delta0022
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0022
Activin receptor type-2B0022
Bone morphogenetic protein receptor type-20022
Protein-tyrosine kinase 60022
cGMP-dependent protein kinase 1 0022
Cyclin-dependent kinase 130022
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0022
Protein-tyrosine kinase 2-beta0022
Sodium channel protein type 5 subunit alpha0202
Maternal embryonic leucine zipper kinase0022
Structural maintenance of chromosomes protein 1A0022
Chromodomain-helicase-DNA-binding protein 40022
Peroxisomal acyl-coenzyme A oxidase 10022
Ephrin type-A receptor 70011
Delta(24)-sterol reductase0022
Ribosomal protein S6 kinase alpha-10022
Dual specificity testis-specific protein kinase 10022
Myosin light chain kinase, smooth muscle0022
Mitogen-activated protein kinase 110022
Serine/threonine-protein kinase STK110022
Serine/threonine-protein kinase N10022
Serine/threonine-protein kinase N20022
Mitogen-activated protein kinase 140022
Calcium/calmodulin-dependent protein kinase type IV0022
Mitogen-activated protein kinase kinase kinase 110022
Discoidin domain-containing receptor 20022
AP2-associated protein kinase 10022
Myosin light chain kinase 30022
Putative heat shock protein HSP 90-beta 20022
Serine/threonine-protein kinase MRCK alpha0022
Serine/threonine-protein kinase MRCK gamma0022
Acyl-CoA dehydrogenase family member 100022
Serine/threonine-protein kinase N30022
Serine/threonine-protein kinase ULK30022
Uncharacterized protein FLJ452520022
Acyl-CoA dehydrogenase family member 110022
Serine/threonine-protein kinase/endoribonuclease IRE20022
Serine/threonine-protein kinase MARK20022
ATP-dependent RNA helicase DHX300022
Serine/threonine-protein kinase TAO10022
STE20-related kinase adapter protein alpha0022
Myosin-140022
AarF domain-containing protein kinase 10022
ATP-dependent RNA helicase DDX420011
Mitogen-activated protein kinase kinase kinase kinase 30022
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0011
Regulatory-associated protein of mTOR0202
Atypical kinase COQ8A, mitochondrial0022
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0022
Mitogen-activated protein kinase 150022
Serine/threonine-protein kinase Nek90022
Serine/threonine-protein kinase Nek70011
ATP-dependent RNA helicase DDX10022
Mitogen-activated protein kinase kinase kinase kinase 10022
MAP/microtubule affinity-regulating kinase 40022
Serine/threonine-protein kinase Nek10022
PAS domain-containing serine/threonine-protein kinase0022
Calcium/calmodulin-dependent protein kinase kinase 20022
EKC/KEOPS complex subunit TP53RK0022
Dual specificity testis-specific protein kinase 20022
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0022
Mitogen-activated protein kinase kinase kinase 50022
Mitogen-activated protein kinase kinase kinase 30022
Eukaryotic translation initiation factor 2-alpha kinase 10022
Target of rapamycin complex subunit LST80202
Nucleolar GTP-binding protein 10022
Serine/threonine-protein kinase D20022
NUAK family SNF1-like kinase 20011
RNA cytidine acetyltransferase0022
Serine/threonine-protein kinase SIK20022
STE20-like serine/threonine-protein kinase 0022
Serine/threonine-protein kinase TAO30022
dCTP pyrophosphatase 10022
Dual specificity protein kinase CLK40022
Casein kinase I isoform gamma-10022
Phenylalanine--tRNA ligase beta subunit0022
BMP-2-inducible protein kinase0022
Obg-like ATPase 10022
Midasin0022
Interleukin-1 receptor-associated kinase 40022
Mitogen-activated protein kinase kinase kinase 200022
Cyclin-dependent kinase 120022
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130011
Serine/threonine-protein kinase 260022
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0022
Serine/threonine-protein kinase NLK0022
5'-AMP-activated protein kinase subunit gamma-20022
Serine/threonine-protein kinase TBK10022
Septin-90022
Potassium voltage-gated channel subfamily D member 30101
Ribosomal protein S6 kinase alpha-60022
TRAF2 and NCK-interacting protein kinase0022
Serine/threonine-protein kinase TAO20022
Long-chain-fatty-acid--CoA ligase 50011
RAC-gamma serine/threonine-protein kinase0022
Serine/threonine-protein kinase SIK30022
Mitogen-activated protein kinase kinase kinase 20022
Thyroid hormone receptor-associated protein 30022
Mitogen-activated protein kinase kinase kinase kinase 50022
Receptor-interacting serine/threonine-protein kinase 30022
Serine/threonine-protein kinase MRCK beta0022
Interleukin-1 receptor-associated kinase 30022
Casein kinase I isoform gamma-30022
Mitogen-activated protein kinase kinase kinase 40022
Chain A, Uracil Phosphoribosyltransferase0101
Skn7p0001
pregnane X receptor1001
nonstructural protein 13003
nuclear factor erythroid 2-related factor 2 isoform 25005
huntingtin isoform 22002
flap endonuclease 14004
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
Vpr1001
Solute carrier family 22 member 80001
Thymidylate synthase0303
Aromatase0101
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
caspase 7, apoptosis-related cysteine protease2002
caspase-32002
Caspase-72002
NPC intracellular cholesterol transporter 1 precursor1001
caspase-32002
ras-related protein Rab-9A1001
Sodium-dependent noradrenaline transporter0101
Potassium channel subfamily K member 20213
Albumin0011
Sodium channel protein type 1 subunit alpha0101
Cytochrome P450 2C80101
Dipeptidyl peptidase 40101
Acetylcholinesterase0202
Prostaglandin G/H synthase 10101
Potassium voltage-gated channel subfamily C member 10101
Cytochrome P450 2J20303
Gastrin/cholecystokinin type B receptor 0101
Cytochrome P450 1B10101
Sigma intracellular receptor 20101
Sigma non-opioid intracellular receptor 10202
Sodium-dependent serotonin transporter0101
Transporter0202
Beta-2 adrenergic receptor0213
Sigma non-opioid intracellular receptor 10101
Histamine H3 receptor0202
PPM1D protein2002
NADPH oxidase 10101
glucocerebrosidase1001
Snq2p0001
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10202
Receptor tyrosine-protein kinase erbB-20101
Adenosine receptor A30202
Beta-3 adrenergic receptor0213
Substance-K receptor0404
Trypanothione reductase0202
Melanocortin receptor 50202
Pleiotropic ABC efflux transporter of multiple drugs0102
Mu-type opioid receptor09212
Delta-type opioid receptor0618
Kappa-type opioid receptor08211
P-selectin0101
Gamma-aminobutyric acid 0112
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0011
bromodomain adjacent to zinc finger domain 2B2002
transcriptional regulator ERG isoform 34004
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
Histone deacetylase 30101
Gamma-aminobutyric acid receptor subunit alpha-60112
Gamma-aminobutyric acid receptor subunit gamma-20112
Gamma-aminobutyric acid receptor subunit delta0112
Sodium- and chloride-dependent GABA transporter 10101
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit alpha-20112
Gamma-aminobutyric acid receptor subunit alpha-30112
Gamma-aminobutyric acid receptor subunit gamma-30112
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit beta-10112
Histone deacetylase 40101
Gamma-aminobutyric acid receptor subunit alpha-10112
Gamma-aminobutyric acid receptor subunit beta-30112
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
Histone deacetylase 10101
Sterol O-acyltransferase 10011
Proton-coupled amino acid transporter 10202
Gamma-aminobutyric acid receptor subunit alpha-50112
Gamma-aminobutyric acid receptor subunit pi0112
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Histone deacetylase 80101
Gamma-aminobutyric acid receptor subunit alpha-40112
Platelet glycoprotein VI0011
Gamma-aminobutyric acid receptor subunit theta0112
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid receptor subunit gamma-10112
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10404
Serine racemase0101
Olfactory receptor 51E20011
Sodium- and chloride-dependent glycine transporter 20101
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase0101
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase0101
Glutamine synthetase 0101
Cytochrome P450 71B10102
Glutamine synthetase 0101
2-dehydro-3-deoxyphosphooctonate aldolase0101
Solute carrier family 22 member 30102
Sigma intracellular receptor 20101
Cyclic GMP-AMP synthase0101
Toll-like receptor 90101
Toll-like receptor 70101
Chain A, JmjC domain-containing histone demethylation protein 3A1001
WRN1001
integrase, partial0101
lens epithelium-derived growth factor p750101
apical membrane antigen 1, AMA11001
pyruvate kinase1001
hexokinase-4 isoform 12002
glucokinase regulatory protein2002
importin subunit beta-1 isoform 12002
snurportin-12002
DNA polymerase eta isoform 12002
Polyphenol oxidase 20103
Carbonic anhydrase 120002
Plasma kallikrein0002
Carbonic anhydrase 30002
Polyunsaturated fatty acid lipoxygenase ALOX150202
Tyrosinase0101
Carbonic anhydrase 40002
Carbonic anhydrase 60002
Adenosine receptor A10103
Adenosine receptor A2a0002
Carbonic anhydrase 5A, mitochondrial0002
Carbonic anhydrase0002
Carbonic anhydrase 70002
Solute carrier family 15 member 10101
Carbonic anhydrase0002
SLC16A10 protein0002
Carbonic anhydrase 90002
Carbonic anhydrase 0002
Carbonic anhydrase0002
Carbonic anhydrase0002
Carbonic anhydrase 0002
Monocarboxylate transporter 100002
Carbonic anhydrase 150002
Carbonic anhydrase 130001
Carbonic anhydrase 140002
Carbonic anhydrase 5B, mitochondrial0002
phosphoglycerate kinase1001
Beta-2 adrenergic receptor0415
Chain A, protease0101
Chain B, protease0101
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, PROTEASE RETROPEPSIN0101
Chain B, PROTEASE RETROPEPSIN0101
Chain A, Protease Retropepsin0101
Chain B, Protease Retropepsin0101
Chain A, Protease Retropepsin0101
Chain B, Protease Retropepsin0101
Smad33003
nuclear receptor subfamily 1, group I, member 23003
Albumin0015
Gag-Pol polyprotein0202
Gag-Pol polyprotein0202
Gag-Pol polyprotein0202
Gag-Pol polyprotein0202
Gag-Pol polyprotein0202
Protease 0327
CAAX prenyl protease 1 homolog0101
Plasmepsin V 0202
Protease 0437
lethal(3)malignant brain tumor-like protein 1 isoform I1001
Cytochrome P450 2B60101
Mas-related G-protein coupled receptor member X20022
Aldehyde oxidase 1 0101
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
ClpP1001
Thymidylate synthase 0101
alpha-galactosidase2002
Thymidylate synthase 0101
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
transactivating tegument protein VP16 [Human herpesvirus 1]0101
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0202
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0112
Trifunctional purine biosynthetic protein adenosine-30101
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0416
Mu-type opioid receptor0418
Kappa-type opioid receptor0315
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60001
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200202
Dihydrofolate reductase 0101
Solute carrier family 22 member 80001
Solute carrier family 22 member 60202
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier organic anion transporter family member 1B30203
Solute carrier family 22 member 110001
Nuclear receptor subfamily 1 group I member 20044
Glucocorticoid receptor04110
Glycine receptor subunit alpha-10404
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
Nuclear receptor subfamily 1 group I member 20011
Beta-1 adrenergic receptor 0011
Beta-1 adrenergic receptor0112
Beta-1 adrenergic receptor0101
Opioid receptor, delta 1b 0101
Acetylcholinesterase0315
Opioid receptor homologue0101
Acyl-CoA desaturase 10101
Muscarinic acetylcholine receptor M30202
Muscarinic acetylcholine receptor M40303
Muscarinic acetylcholine receptor M50202
Translocator protein0213
Proteinase-activated receptor 10112
Delta-type opioid receptor0304
Kappa-type opioid receptor0214
UDP-glucuronosyltransferase 1A30001
Kappa-type opioid receptor0202
Mu-type opioid receptor0215
Nociceptin receptor0101
Mu-type opioid receptor0101
Mu-type opioid receptor0303
Mu-type opioid receptor0101
Rap guanine nucleotide exchange factor 41001
5-hydroxytryptamine receptor 3E0202
Neuronal acetylcholine receptor subunit alpha-40213
Transient receptor potential cation channel subfamily A member 10011
5-hydroxytryptamine receptor 3B0202
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit beta0213
Acetylcholine receptor subunit gamma0213
Acetylcholine receptor subunit delta0213
Acetylcholine receptor subunit gamma0213
Neuronal acetylcholine receptor subunit alpha-40101
Acetylcholine receptor subunit beta0213
Cytochrome P450 2A60213
Neuronal acetylcholine receptor subunit beta-20213
Cytochrome P450 2A50101
Acetylcholine receptor subunit beta-like 20202
Neuronal acetylcholine receptor subunit alpha-50011
Neuronal acetylcholine receptor subunit beta-40213
Muscarinic acetylcholine receptor M40101
Neuronal acetylcholine receptor subunit alpha-30213
Neuronal acetylcholine receptor subunit alpha-70224
Neuronal acetylcholine receptor subunit alpha-40213
5-hydroxytryptamine receptor 3A0202
Neuronal acetylcholine receptor subunit alpha-70202
Acetylcholine-binding protein0112
Acetylcholine receptor subunit epsilon0011
Neuronal acetylcholine receptor subunit beta-30112
Acetylcholine receptor subunit delta0213
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit alpha-60112
Cytochrome P450 2A130112
Neuronal acetylcholine receptor subunit alpha-50202
Liver carboxylesterase B-10101
5-hydroxytryptamine receptor 3D0202
Transient receptor potential cation channel subfamily A member 10011
Neuronal acetylcholine receptor subunit beta-30202
Neuronal acetylcholine receptor subunit beta-40202
Neuronal acetylcholine receptor subunit alpha-30202
Soluble acetylcholine receptor0101
5-hydroxytryptamine receptor 3C0202
Neuronal acetylcholine receptor subunit alpha-20202
Neuronal acetylcholine receptor subunit beta-20213
Neuronal acetylcholine receptor subunit alpha-60202
Integrin beta0011
Glycoprotein IIb0011
lysosomal alpha-glucosidase preproprotein1001
FAD-linked sulfhydryl oxidase ALR0001
UDP-glucuronosyltransferase 1A40002
Histamine H1 receptor0123
Alpha-1A adrenergic receptor0101
Alpha-1B adrenergic receptor0101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 2 subunit alpha0101
Aldo-keto reductase family 1 member B10101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0102
Sodium channel protein type 9 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Acetylcholinesterase0101
Cholinesterase0202
Acetylcholinesterase 0101
Acetylcholinesterase0101
Acetylcholinesterase0101
Cholinesterase0203
Cholinesterase0101
Acyl-CoA:cholesterol acyltransferase 0101
Carboxylic ester hydrolase 0101
Carboxylic ester hydrolase 0101
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Prostaglandin G/H synthase 20101
Nociceptin receptor0011
Estrogen receptor beta0202
Chain A, HIV-1 PROTEASE0101
Chain B, HIV-1 PROTEASE0101
Chain A, POL polyprotein0101
Chain B, POL polyprotein0101
Chain A, POL polyprotein0101
Chain B, POL polyprotein0101
Chain A, Endothiapepsin0101
Chain A, Endothiapepsin0101
Solute carrier organic anion transporter family member 2B1 0202
Gag-Pol polyprotein0101
Cytochrome P450 3A50202
UDP-glucuronosyltransferase 1A1 0101
Thromboxane-A synthase 0101
Vasopressin V1a receptor0202
Thromboxane-A synthase0001
Sodium/bile acid cotransporter0101
Multidrug and toxin extrusion protein 20101
Solute carrier organic anion transporter family member 1B10404
Nitric oxide synthase, brain0011
Tyrosine-protein kinase JAK20011
Cyclin-dependent kinase-like 50011
Eukaryotic translation initiation factor 4E0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Serine/threonine-protein kinase receptor R30011
Peptidyl-prolyl cis-trans isomerase FKBP1A0426
Peptidyl-prolyl cis-trans isomerase FKBP1B0022
Protein kinase C zeta type0011
Cyclin-dependent kinase 180011
Tyrosine-protein kinase Mer0011
Peptidyl-prolyl cis-trans isomerase FKBP50202
Uncharacterized aarF domain-containing protein kinase 50011
Programmed cell death protein 40011
MAP kinase-activated protein kinase 50011
Misshapen-like kinase 10011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase mTOR 0101
Isoleucine--tRNA ligase, mitochondrial0011
Serine/threonine-protein kinase ICK0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Serine/threonine-protein kinase 240011
UDP-glucuronosyltransferase 2B70001
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Splicing factor 3B subunit 30101
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Tubulin--tyrosine ligase0101
Taste receptor type 2 member 140001
glycogen synthase kinase-3 beta isoform 10011
Thymidine kinase, cytosolic0001
Dipeptidyl peptidase 40101
Adenosylhomocysteinase0101
Adenosine deaminase 0001
RNA-directed RNA polymerase 0112
Sphingosine-1-phosphate lyase 10101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]