Neurally Mediated Faint

Loss of consciousness due to a reduction in blood pressure that is associated with an increase in vagal tone and peripheral vasodilation.

Synonym
Syncope, Vasovagal
Syncope, Cerebral
Syncope, Vasovagal, Neurally-Mediated
Neurally Mediated Faint
Syncope, Malignant Neurocardiogenic
Syncope, Neurocardiogenic
Syncope, Neurogenic
Syncope, Supine
Syncope, Vasodepressor

Excerpt	Reference
"Vasovagal syncope is a common clinical disorder which has been traditionally related to a vasovagal reflex precipitated by an initial excess sympathetic stimulation."	( Fouad-Tarazi, FM; Shehadeh, AA; Yamanouchi, Y, 1998)
"Vasovagal syncope is a common disorder of autonomic cardiovascular regulation that can be very disabling and result in a significant level of psychosocial and physical limitations."	( Atiga, WL; Calkins, H; Rowe, P, 1999)
"Vasovagal syncope is a common disorder of autonomic cardiovascular regulation."	( Calkins, H, 1999)
"Therapy of vasovagal syncope is still a subject of debate."	( Mitro, P; Rybár, AR; Trejbal, D, 1999)
"The treatment of neurocardiogenic syncope is insufficient in many cases."	( Ector, H; Heidbüchel, H; Reybrouck, T; Van de Werf, F, 2000)
"Vasovagal syncope is the most common abnormal response to upright posture and occurs in all age groups."	( Bloomfield, DM, 2002)
"Posture-related vasovagal syncope is by far the most frequent cause of transient loss of consciousness, and present pharmacological and cardiac pacing treatment remains unsatisfactory."	( Krediet, CT; Linzer, M; van Dijk, N; van Lieshout, JJ; Wieling, W, 2002)
"Vasovagal syncope is an exaggerated form of the common faint affecting all age groups."	( Donaldson, P; Frearson, R; Kenny, R; Lawson, J; Newton, JL, 2003)
"Vasovagal syncope is defined as a reflex loss of consciousness related to reaction to various stimuli as orthostatic stress, pain or emotions connected with loss of muscle postural tone."	( Gajek, J; Zyśko, D, 2003)
"Vasovagal syncope is defined as a reflex loss of consciousness related to reaction to various stimuli as orthostatic stress, pain or emotions connected with loss of muscle postural tone."	( Gajek, J; Zyśko, D, 2003)
"Vasovagal syncope is the most common cause of transient loss of consciousness, and recurrent vasovagal fainting has a profound impact on quality of life."	( Bogert, LW; Immink, RV; Kim, YS; Krediet, CT; van Lieshout, JJ; Wieling, W, 2006)
"Vasovagal syncope is a common and challenging problem that may result in injury and causes substantial anxiety among patients and their relatives."	( Abali, G; Amasyali, B; Aytemir, K; Bariş Kaya, E; Kabakçi, G; Kocabaş, U; Köse, S; Nazli, N; Oto, A; Ozkutlu, H; Tokgözoğlu, L, 2007)
"Vasovagal syncope is a common problem associated with a poor quality of life, which improves when the frequency of syncope is reduced."	( Faris, PD; McRae, M; Raj, SR; Sheldon, RS, 2012)
"Vasovagal syncope is the main cause of syncope."	( Etemadi, AQ; Sunthorn, H, 2014)
"Vasovagal or neurocardiogenic syncope is a common clinical situation and, as with other entities associated with orthostatic intolerance, the underlying condition is a dysfunction of the autonomic nervous system."	( Cárdenas, M; Gómez-Flores, JR; González-Hermosillo, JA; Márquez, MF; Ruíz-Siller, TJ, 2016)
"Vasovagal syncope is the most frequent cause of syncope in pediatrics, in which a detailed clinical history is enough to make the diagnosis."	( Bustillos-García, GA; García, A; Rivera-Rodríguez, L, 2020)
"Vasovagal syncope is the most frequent cause of syncope in pediatrics, in which a detailed clinical history is enough to make the diagnosis."	( Bustillos-García, GA; García, A; Rivera-Roodríguez, L, 2020)
"Vasovagal syncope is the most common cause of syncope in childhood and its treatment is not at a satisfactory level yet."	( Atik, F; Bagrul, D; Ece, I; Kavurt, AV; Yılmaz, A, 2021)
"Recurrent vasovagal syncope is common, responds poorly to treatment, and causes physical trauma and poor quality of life."	( Ayala-Paredes, F; Faris, P; Guzman, J; Krahn, AD; Kus, T; Marquez, M; Maxey, C; Morillo, CA; Raj, SR; Ritchie, D; Safdar, S; Sheldon, R; Tang, A, 2021)

Excerpt	Reference
"Patients with vasovagal syncope have also demonstrated numerous "exaggerated" neurohumoral responses to syncope."	( Eckberg, DL; Ellenbogen, KA; Gilligan, DM; Morillo, CA; Smith, ML; Wood, MA, 1997)
"Few therapies for vasovagal syncope have been proven effective."	( Connolly, S; Rose, S; Sheldon, R, 2003)
"Vasovagal syncope has a strong genetic component."	( Donaldson, P; Frearson, R; Kenny, R; Lawson, J; Newton, JL, 2003)

Excerpt	Reference
"In 16 patients with neurocardiogenic syncope, changes in endogenous catecholamine concentrations were determined during repeated tilt table testing before and during treatment with metoprolol."	( Hohnloser, SH; Kalusche, D; Klingenheben, T; Li, YG; Schöpperl, M, 1996)
"In patients with neurocardiogenic syncope who show both an increase in epinephrine concentration during tilt test and sinus tachycardia prior to the onset of symptoms, beta-blocker treatment is very effective."	( Hohnloser, SH; Kalusche, D; Klingenheben, T; Li, YG; Schöpperl, M, 1996)
"Some patients with neurocardiogenic syncope continue to have recurrent syncope or presyncope despite the use of currently available drug therapy."	( Akhtar, M; Biehl, M; Blanck, Z; Deshpande, S; Dhala, A; Jazayeri, MR; Maglio, C; Sra, J, 1997)
"Pharmacological therapy of neurocardiogenic syncope is often limited by the relatively low response rate to such treatment."	( Credner, S; Hohnloser, SH; Klingenheben, T, 1999)
"The treatment of neurocardiogenic syncope is insufficient in many cases."	( Ector, H; Heidbüchel, H; Reybrouck, T; Van de Werf, F, 2000)
"The recurrence of neurocardiogenic syncope in highly symptomatic patients treated with atenolol is similar to that of patients treated with placebo."	( Madrid, AH; Manzano, JG; Moro, C; Ortega, J; Peña, G; Rebollo, JG; Sánchez, A; Segovia, JG, 2001)
"27 patients with frequent neurogenic syncopes (NS) resistant to conventional therapy were treated with clonazepam."	( Musaeva, ZA, 2001)
"Many drugs have been used for the treatment of vasovagal syncope (beta-blockers, disopyramide, scopolamine, clonidine, theophylline, fludrocortisone, ephedrine, dihydroergotamine, etilefrine, midodrine, clonidine, serotonin reuptake inhibitors, enalapril)."	( Brignole, M, 2003)
"Tilt training is a new treatment for vasovagal syncope."	( Gajek, J; Halawa, B; Mazurek, W; Zyśko, D, 2006)
"However, treatment of vasovagal syncope with standard pharmacologic approaches is not satisfactory."	( Abali, G; Amasyali, B; Aytemir, K; Bariş Kaya, E; Kabakçi, G; Kocabaş, U; Köse, S; Nazli, N; Oto, A; Ozkutlu, H; Tokgözoğlu, L, 2007)
"Initial treatment of vasovagal syncope (VVS) consists of assuring an adequate fluid and salt intake, regular exercise and application of physical counterpressure manoeuvres."	( Go-Schön, IK; Harms, MP; Lenders, JW; Luitse, JS; Reitsma, JB; Romme, JJ; Ruiter, JH; van Dijk, N; Wieling, W, 2010)
"Initial treatment of vasovagal syncope (VVS) consists of advising adequate fluid and salt intake, regular exercise, and physical counterpressure manoeuvres."	( Go-Schön, IK; Reitsma, JB; Romme, JJ; van Dijk, N; Wieling, W, 2011)
"The cornerstone of the treatment of vasovagal syncope (VVS) is lifestyle modifications; however, some patients incur life-disturbing attacks despite compliance with these treatments which underscores the importance of pharmacological interventions."	( Akbarzadeh, MA; Alaeddini, F; Aminorroaya, A; Apakuppakul, S; Ariannejad, H; Bozorgi, A; Emkanjoo, Z; Jalali, A; Joharimoghadam, A; Kiarsi, M; Mohammadi, R; Mohsenizade, A; Mollazadeh, R; Ngarmukos, T; Oraii, A; Oraii, S; Rahimi, B; Sadeghian, S; Shahabi, J; Tajdini, M; Tavolinejad, H, 2021)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	103 (18.33)	12.5806
2000's	254 (45.20)	18.1394
2010's	144 (25.62)	28.8240
2020's	61 (10.85)	9.53

Drug	Relationship Strength	Studies	Trials
acetic acid	low	1	0
carbon monoxide	low	1	0
citric acid, anhydrous	low	3	0
hydrogen sulfide	low	2	0
glycerol	low	1	0
dihydroxyphenylalanine	medium	1	1
nitrates	medium	12	1
pyridoxine	low	1	0
urea	low	1	0
phenytoin	low	1	0
acebutolol	low	1	0
acetaminophen	low	1	0
acetazolamide	low	1	0
theophylline	low	4	0
amitriptyline	medium	1	1
atenolol	medium	14	3
bisoprolol	low	1	0
bupivacaine	low	2	0
caffeine	medium	1	1
carbamazepine	low	1	0
chlorpheniramine	low	1	0
cisapride	low	1	0
citalopram	low	2	0
clomipramine	medium	6	2
clonazepam	medium	2	2
clonidine	medium	4	3
amphetamine	medium	1	1
diclofenac	medium	1	1
dipyridamole	medium	3	1
disopyramide	medium	13	1
valproic acid	low	1	0
edrophonium	medium	2	1
etilefrine	medium	5	3
fentanyl	low	2	0
fluoxetine	medium	6	2
glyphosate	low	1	0
lidocaine	low	4	0
indomethacin	medium	1	1
avapro	low	1	0
isoproterenol	medium	61	17
mepivacaine	medium	2	1
methylphenidate	medium	1	1
metoprolol	medium	27	10
midazolam	low	3	0
midodrine	medium	46	14
apnea	low	4	0
nifedipine	low	1	0
nitroglycerin	medium	74	25
benoxinate	low	1	0
pindolol	medium	4	1
prilocaine	low	1	0
procaine	low	1	0
propantheline	medium	1	1
propofol	low	2	0
propranolol	medium	18	6
sibutramine	low	3	0
phentolamine	low	1	0
aldosterone	low	6	0
adenosine diphosphate	low	1	0
phenylephrine	medium	6	1
medroxyprogesterone acetate	low	1	0
isoleucine	low	1	0
arginine	low	1	0
triamcinolone acetonide	low	1	0
isosorbide dinitrate	medium	13	5
1-naphthylamine	low	1	0
yohimbine	medium	3	3
ephedrine	low	2	0
galantamine	low	1	0
phenylpropanolamine	low	1	0
dihydroergotamine	low	1	0
methoxyhydroxyphenylglycol	medium	1	1
isosorbide	low	1	0
magnesium sulfate	low	1	0
phosphoric acid, trisodium salt	low	1	0
fludrocortisone	medium	26	4
carticaine	low	1	0
tramadol	low	1	0
substance p	low	1	0
dobutamine	low	1	0
sq-11725	medium	2	2
propiconazole	low	2	0
paroxetine	medium	6	4
fomesafen	medium	52	6
atomoxetine hydrochloride	medium	5	5
esmolol	low	3	0
ibutilide	low	1	0
3-iodobenzylguanidine	low	6	0
adenosine	medium	20	4
pirmenol	low	1	0
triazoles	low	1	0
fluorodeoxyglucose f18	low	2	0
sertraline	low	1	0
dapoxetine	medium	2	1
fibrinogen	low	1	0
3,4-dihydroxyphenylglycol	medium	1	1
homocysteine	low	1	0
droxidopa	low	1	0
5-fluorodopamine	medium	1	1
reboxetine	low	2	0
tamsulosin	medium	1	1
omega-n-methylarginine	low	2	0
ivabradine	low	1	0
didesmethylcitalopram	low	1	0
angiotensin ii	low	1	0
atropine	medium	16	3
quinidine	low	2	0
zithromax	low	1	0
sodium bicarbonate	low	1	0
arginine vasopressin	medium	3	1
digoxin	low	2	0
thromboxane a2	low	1	0
hydrocodone	low	2	0
naloxone	medium	2	1
dexmedetomidine	low	1	0
cysteine	medium	4	1
phosphorus	medium	1	1
dimethylarginine	low	1	0
veratridine	low	2	0
losartan potassium	low	1	0
scopolamine hydrobromide	low	1	0
pituitrin	low	6	0
atrial natriuretic factor	low	3	0
beta-endorphin	medium	1	1
neuropeptide y	low	2	0
angiotensinogen	low	2	0
endothelin-1	low	7	0
cardiovascular agents	medium	12	3
piperidines	low	1	0
natriuretic peptide, brain	low	4	0
adrenomedullin	low	5	0
vitamin b 12	low	2	0
exudates	low	1	0
folic acid	low	1	0
olanzapine	low	1	0
eye	low	1	0
technetium tc 99m bicisate	medium	4	1

Protein Targets (1,228)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	15	0	0	15
Chain A, HADH2 protein	7	0	0	7
Chain B, HADH2 protein	7	0	0	7
RAR-related orphan receptor gamma	21	0	0	21
GLI family zinc finger 3	32	0	0	32
AR protein	35	0	0	35
aldehyde dehydrogenase 1 family, member A1	16	0	0	16
thyroid stimulating hormone receptor	17	0	0	17
estrogen receptor 2 (ER beta)	14	0	0	14
nuclear receptor subfamily 1, group I, member 3	24	0	0	24
progesterone receptor	19	0	0	19
glucocorticoid receptor [Homo sapiens]	23	0	0	23
retinoic acid nuclear receptor alpha variant 1	24	0	0	24
estrogen-related nuclear receptor alpha	32	0	0	32
pregnane X nuclear receptor	22	0	0	22
estrogen nuclear receptor alpha	36	0	0	36
aryl hydrocarbon receptor	12	0	0	12
thyroid stimulating hormone receptor	15	0	0	15
activating transcription factor 6	14	0	0	14
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	14	0	0	14
v-jun sarcoma virus 17 oncogene homolog (avian)	15	0	0	15
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
thyroid hormone receptor beta isoform 2	24	0	0	24
nuclear factor erythroid 2-related factor 2 isoform 1	28	0	0	28
cytochrome P450 3A4 isoform 1	16	0	0	16
Gamma-aminobutyric acid receptor subunit pi	16	6	5	27
Voltage-dependent calcium channel gamma-2 subunit	14	0	0	14
Gamma-aminobutyric acid receptor subunit beta-1	16	6	5	27
Gamma-aminobutyric acid receptor subunit delta	16	6	5	27
Gamma-aminobutyric acid receptor subunit gamma-2	16	6	5	27
Glutamate receptor 2	15	0	0	15
Gamma-aminobutyric acid receptor subunit alpha-5	16	6	5	27
Gamma-aminobutyric acid receptor subunit alpha-3	16	6	5	27
Gamma-aminobutyric acid receptor subunit gamma-1	16	6	5	27
Gamma-aminobutyric acid receptor subunit alpha-2	16	6	5	27
Gamma-aminobutyric acid receptor subunit alpha-4	16	6	5	27
Gamma-aminobutyric acid receptor subunit gamma-3	16	6	5	27
Gamma-aminobutyric acid receptor subunit alpha-6	16	6	5	27
Gamma-aminobutyric acid receptor subunit alpha-1	16	6	5	27
Gamma-aminobutyric acid receptor subunit beta-3	16	6	5	27
Gamma-aminobutyric acid receptor subunit beta-2	16	6	5	27
Kelch-like ECH-associated protein 1	0	0	1	1
GABA theta subunit	16	6	5	27
Gamma-aminobutyric acid receptor subunit epsilon	16	6	5	27
Histone acetyltransferase KAT8	0	1	0	1
dopamine D1 receptor	5	0	0	5
thioredoxin reductase	23	0	0	23
GLS protein	18	0	0	18
Thrombopoietin	4	0	0	4
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	10	0	0	10
cytochrome P450 2D6 isoform 1	14	0	0	14
cytochrome P450 2C19 precursor	7	0	0	7
ras-related protein Rab-9A	8	0	0	8
histone acetyltransferase KAT2A isoform 1	8	0	0	8
lethal factor (plasmid)	10	0	0	10
POU domain, class 2, transcription factor 1	0	0	0	4
Spike glycoprotein	20	0	2	22
ATP-dependent phosphofructokinase	14	0	0	14
Alpha-1B adrenergic receptor	0	20	5	25
Beta-1 adrenergic receptor	0	8	3	14
Alpha-2B adrenergic receptor	0	19	7	26
Alpha-2C adrenergic receptor	0	18	7	25
Alpha-2A adrenergic receptor	0	18	7	25
Alpha-1D adrenergic receptor	0	18	5	24
Alpha-1A adrenergic receptor	0	24	6	30
Beta-2 adrenergic receptor	0	3	0	3
Solute carrier family 22 member 1	0	17	0	20
Beta-2 adrenergic receptor	0	16	10	27
Beta-1 adrenergic receptor	0	21	9	30
Beta-3 adrenergic receptor	0	10	9	19
5-hydroxytryptamine receptor 1A	0	27	5	33
ATAD5 protein, partial	15	0	0	15
Microtubule-associated protein tau	11	0	0	11
Smad3	6	0	0	6
EWS/FLI fusion protein	12	0	0	12
retinoid X nuclear receptor alpha	21	0	0	21
peroxisome proliferator activated receptor gamma	19	0	0	19
chromobox protein homolog 1	26	0	0	26
peripheral myelin protein 22	18	0	0	18
ATP-binding cassette sub-family C member 3	0	34	0	34
Multidrug resistance-associated protein 4	0	34	0	35
Solute carrier family 22 member 6	0	3	0	3
Carbonic anhydrase 12	0	4	1	7
UDP-glucuronosyltransferase 1A9	0	1	0	5
Bile salt export pump	0	7	0	7
Bile salt export pump	0	48	0	48
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	11	1	16
Carbonic anhydrase 2	0	11	1	15
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	3	0	5
Prostaglandin G/H synthase 1	0	4	0	5
Carbonic anhydrase 3	0	4	1	7
Cytochrome P450 3A4	0	20	0	22
Cytochrome P450 2D6	0	18	0	18
Cytochrome P450 2C9	0	13	0	15
Polyunsaturated fatty acid lipoxygenase ALOX15	0	7	0	7
Sulfotransferase 1A1	0	0	0	1
UDP-glucuronosyltransferase 1-6	0	4	0	6
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	4	0	5
Carbonic anhydrase 4	0	8	1	10
Prostaglandin G/H synthase 1	0	6	0	6
Carbonic anhydrase 6	0	5	1	7
Carbonic anhydrase 5A, mitochondrial	0	7	1	10
Prostaglandin G/H synthase 2	0	4	1	6
Carbonic anhydrase 7	0	5	1	7
Nuclear receptor ROR-gamma	8	1	1	10
Cytochrome P450 2J2	0	9	0	9
Carbonic anhydrase 9	0	8	1	11
Canalicular multispecific organic anion transporter 1	0	32	0	32
Carbonic anhydrase 15	0	4	0	5
Carbonic anhydrase 13	0	4	0	5
Carbonic anhydrase 14	0	4	1	7
Carbonic anhydrase 5B, mitochondrial	0	7	1	10
toxin B	0	0	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	11	0	0	11
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	14	0	0	14
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	2	0	2
GALC protein	4	0	0	4
cytochrome P450 family 3 subfamily A polypeptide 4	24	0	0	24
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	2	0	2
arylsulfatase A	18	0	0	18
Carbonic anhydrase	0	2	0	2
euchromatic histone-lysine N-methyltransferase 2	36	0	0	36
Bloom syndrome protein isoform 1	8	0	0	8
thyroid hormone receptor beta isoform a	13	0	0	13
geminin	28	0	0	28
survival motor neuron protein isoform d	5	0	0	5
muscleblind-like protein 1 isoform 1	3	0	0	3
Carbonic anhydrase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Glycogen phosphorylase, muscle form	0	2	0	2
Renin	0	4	0	4
Carbonic anhydrase 2	0	2	0	2
Cathepsin B	0	1	0	1
Steryl-sulfatase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	11	1	12
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Cytochrome P450 2C8	0	3	0	3
Cytochrome P450 2A6	0	3	0	3
5-hydroxytryptamine receptor 2A	0	13	1	14
Androgen receptor	0	6	0	6
Translocator protein	0	2	1	3
Cannabinoid receptor 1	0	1	0	1
Cytochrome P450 2B6	0	2	1	3
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	8	1	11
Serum paraoxonase/arylesterase 1	0	2	0	2
Dipeptidyl peptidase 4	0	0	0	1
Endochitinase	0	1	0	1
Adenosine receptor A2a	0	7	3	14
5-hydroxytryptamine receptor 2B	0	11	1	12
Sodium-dependent serotonin transporter	0	8	1	9
Delta-type opioid receptor	0	7	1	9
Cytochrome P450 2C19	0	5	0	5
Delta-type opioid receptor	0	5	2	7
Mu-type opioid receptor	0	6	3	9
Carbonic anhydrase	0	4	0	4
Kappa-type opioid receptor	0	6	2	8
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	7	1	0	8
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	1	0	1
D(2) dopamine receptor	0	10	1	11
Cholinesterase	0	4	0	4
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	6	1	7
Fatty-acid amide hydrolase 1	0	2	0	2
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	1	2
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	2	0	3
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	5	0	5
Delta carbonic anhydrase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	9	1	10
Renin	0	1	0	1
Carbonic anhydrase	0	1	0	1
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	3	1	5
Carbonic anhydrase 4	0	3	0	3
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Tyrosine-protein kinase Lck	0	2	1	3
Tyrosine-protein kinase Fyn	0	2	1	3
Fibrinogen C domain-containing protein 1	0	1	0	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
regulator of G-protein signaling 4	19	0	0	19
NPYLR7B	0	0	3	3
IDH1	15	0	0	15
Histone H2A.x	13	0	0	13
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
mitogen-activated protein kinase 1	10	0	0	10
flap endonuclease 1	5	0	0	5
nuclear receptor ROR-gamma isoform 1	12	0	0	12
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
Sodium/nucleoside cotransporter 2	0	2	0	2
Rap guanine nucleotide exchange factor 3	4	0	0	4
Purine nucleoside phosphorylase	0	1	0	1
Epidermal growth factor receptor	0	5	0	5
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Insulin receptor	0	0	0	1
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	2	2	5
Platelet-derived growth factor receptor beta	0	0	0	1
Adenosine receptor A3	0	9	3	13
Heat shock 70 kDa protein 1A	0	2	1	3
Heat shock cognate 71 kDa protein	0	0	2	2
Fibroblast growth factor receptor 1	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	1	0	1
Endoplasmin	0	1	1	3
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A3	0	3	0	3
Adenosine receptor A2a	0	9	6	18
Adenosine receptor A2b	0	2	1	6
Adenosine receptor A2b	0	4	2	8
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	10	4	19
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	4	0	5
Adenosine receptor A1	0	2	1	3
Adenosine kinase	0	0	0	1
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	4	0	5
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	4	0	4
Phosphatidylinositol 4-kinase type 2-alpha	0	4	0	5
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	4	0	5
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-beta	0	1	1	3
2-dehydropantoate 2-reductase	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	1	0	1
Mu-type opioid receptor	0	9	5	15
Delta-type opioid receptor	0	8	3	12
Kappa-type opioid receptor	0	9	4	14
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	1	1	2
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	8	0	0	8
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
P2Y purinoceptor 11	0	0	1	1
P2Y purinoceptor 12	0	2	1	3
Sensor protein kinase WalK	0	1	0	1
P2X purinoceptor 2	0	0	1	1
nuclear factor erythroid 2-related factor 2 isoform 2	7	0	0	8
Sex hormone-binding globulin	0	0	2	2
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	2	4
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	2
Guanine nucleotide-binding protein G	5	0	0	5
USP1 protein, partial	12	0	0	12
NFKB1 protein, partial	8	0	0	8
cytochrome P450 2D6	22	0	0	22
D(1A) dopamine receptor	19	0	0	19
atrial natriuretic peptide receptor 2 precursor	7	0	0	7
serine/threonine-protein kinase mTOR isoform 1	10	0	0	10
muscarinic acetylcholine receptor M1	15	0	0	15
Polyunsaturated fatty acid lipoxygenase ALOX15B	6	0	0	6
Voltage-dependent L-type calcium channel subunit alpha-1F	0	9	0	9
5-hydroxytryptamine receptor 4	0	28	1	29
Albumin	0	0	3	3
High affinity nerve growth factor receptor	0	1	2	3
Aldo-keto reductase family 1 member B1	0	21	0	21
Muscarinic acetylcholine receptor M2	0	15	2	21
Muscarinic acetylcholine receptor M4	0	16	1	20
Muscarinic acetylcholine receptor M1	0	6	1	9
Muscarinic acetylcholine receptor M3	0	5	1	8
Muscarinic acetylcholine receptor M4	0	5	1	8
Muscarinic acetylcholine receptor M5	0	5	1	8
Muscarinic acetylcholine receptor M5	0	17	1	21
Alpha-2A adrenergic receptor	0	25	7	35
Muscarinic acetylcholine receptor M2	0	6	2	11
Muscarinic acetylcholine receptor M1	0	18	3	25
Angiotensin-converting enzyme	0	17	0	17
D(2) dopamine receptor	0	18	1	19
Alpha-2B adrenergic receptor	0	27	3	33
Alpha-2C adrenergic receptor	0	22	6	31
Muscarinic acetylcholine receptor M3	0	16	2	21
D(1A) dopamine receptor	0	13	1	14
D(1B) dopamine receptor	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	3	0	6
Sodium-dependent noradrenaline transporter	0	26	4	30
Histamine H2 receptor	0	8	0	8
Alpha-1D adrenergic receptor	0	28	6	36
5-hydroxytryptamine receptor 2A	0	20	1	21
5-hydroxytryptamine receptor 2C	0	29	1	30
5-hydroxytryptamine receptor 1B	0	22	1	23
5-hydroxytryptamine receptor 1D	0	7	1	8
5-hydroxytryptamine receptor 1F	0	7	1	8
5-hydroxytryptamine receptor 6	0	2	1	3
Histamine H1 receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	26	5	31
5-hydroxytryptamine receptor 7	0	2	1	3
5-hydroxytryptamine receptor 5A	0	2	1	3
5-hydroxytryptamine receptor 5B	0	2	1	3
Histamine H1 receptor	0	12	1	13
D(3) dopamine receptor	0	17	0	17
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 4 subunit alpha	0	5	0	7
UDP-glucuronosyltransferase 1A3	0	0	0	2
5-hydroxytryptamine receptor 3A	0	4	1	5
5-hydroxytryptamine receptor 2B	0	24	1	25
Histamine H2 receptor	10	2	1	15
5-hydroxytryptamine receptor 6	0	16	1	17
5-hydroxytryptamine receptor 7	0	8	0	8
Voltage-dependent N-type calcium channel subunit alpha-1B	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	9	0	9
Sodium-dependent dopamine transporter	0	19	3	22
Potassium voltage-gated channel subfamily H member 2	0	31	0	31
Voltage-dependent L-type calcium channel subunit alpha-1S	0	9	0	9
Voltage-dependent L-type calcium channel subunit alpha-1C	0	10	0	11
Sodium channel protein type 5 subunit alpha	0	7	0	7
Sodium channel protein type 9 subunit alpha	0	6	0	6
5-hydroxytryptamine receptor 4	0	2	2	5
Nuclear receptor subfamily 3 group C member 3	0	17	0	17
Sodium channel protein type 2 subunit alpha	0	3	0	3
Ataxin-2	19	0	0	19
Sigma non-opioid intracellular receptor 1	0	24	0	24
5-hydroxytryptamine receptor 3B	0	4	1	5
Sodium channel protein type 3 subunit alpha	0	4	0	4
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	2	0	2
Histamine H3 receptor	0	2	0	2
Sodium channel protein type 10 subunit alpha	0	2	0	2
Solute carrier family 22 member 3	0	1	0	1
Phenylethanolamine N-methyltransferase	0	2	0	3
Substance-P receptor	0	3	0	3
Cytochrome P450 2A5	0	1	0	1
Sodium-dependent dopamine transporter	0	11	0	11
Beta-2 adrenergic receptor	0	4	6	12
Sigma non-opioid intracellular receptor 1	0	6	0	6
glucocerebrosidase	4	0	0	4
DNA polymerase kappa isoform 1	7	0	0	7
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	3	1	4
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	5	0	5
Type-1 angiotensin II receptor	0	5	3	9
Type-2 angiotensin II receptor	0	3	0	3
Type-2 angiotensin II receptor	0	3	0	3
TDP1 protein	34	0	0	34
lamin isoform A-delta10	25	0	0	25
neuropeptide S receptor isoform A	4	0	0	4
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
phosphopantetheinyl transferase	12	0	0	12
alpha-galactosidase	4	0	0	4
DNA polymerase iota isoform a (long)	10	0	0	10
Nitric oxide synthase, endothelial	0	1	0	3
Nitric oxide synthase, brain	0	2	0	3
Nitric oxide synthase, brain	0	2	0	3
Nitric oxide synthase, inducible	0	2	0	3
Nitric oxide synthase, inducible	0	2	1	5
Cationic amino acid transporter 3	0	1	0	1
vitamin D3 receptor isoform VDRA	11	0	0	11
Vasopressin V2 receptor	0	2	1	4
Oxytocin receptor	0	1	1	2
Vasopressin V1a receptor	0	0	3	3
Vasopressin V1a receptor	0	2	2	4
Vasopressin V1b receptor	0	1	1	2
Vasopressin V2 receptor	0	0	1	1
Vasopressin V1b receptor	0	1	1	3
Translocator protein	0	1	0	2
Oxytocin receptor	0	1	1	2
Vasopressin V2 receptor	0	1	1	2
Beta-1 adrenergic receptor	0	1	7	10
Fatty acid-binding protein, liver	0	3	0	3
Urease	0	1	0	1
Alpha-1A adrenergic receptor	0	11	10	23
Alpha-1B adrenergic receptor	0	10	8	20
TAR DNA-binding protein 43	6	0	0	6
glp-1 receptor, partial	11	0	0	11
peroxisome proliferator-activated receptor delta	16	0	0	16
Cellular tumor antigen p53	21	0	0	21
Atrial natriuretic peptide receptor 1	0	1	1	2
Atrial natriuretic peptide receptor 1	0	0	1	1
Chain A, 2-oxoglutarate Oxygenase	7	0	0	7
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	3	0	0	3
short transient receptor potential channel 6 isoform 1	0	0	1	1
Muscarinic acetylcholine receptor M1	0	0	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	1	1	3
Chain A, Cruzipain	5	0	0	5
Luciferase	7	0	0	7
G	10	0	0	10
lysosomal alpha-glucosidase preproprotein	4	0	0	4
Interferon beta	18	0	0	18
HLA class I histocompatibility antigen, B alpha chain	10	0	0	10
Neuronal acetylcholine receptor subunit alpha-4	2	2	0	4
Neuronal acetylcholine receptor subunit beta-2	2	2	0	4
Thromboxane A2 receptor	0	0	0	1
Endothelin-1 receptor	0	3	1	4
Sodium/bile acid cotransporter	0	3	0	3
Inositol hexakisphosphate kinase 1	10	0	0	10
Multidrug and toxin extrusion protein 1	0	9	0	9
Leukotriene B4 receptor 2	0	0	1	2
cytochrome P450 2C9, partial	10	0	0	10
Beta-1 adrenergic receptor	0	4	1	5
Potassium channel subfamily K member 3	0	3	0	3
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	2	4	6
Potassium channel subfamily K member 9	0	1	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
farnesoid X nuclear receptor	13	0	0	13
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
Cholinesterase	0	5	0	5
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	3	2	5
Replicase polyprotein 1ab	0	4	2	6
Amine oxidase [flavin-containing] A	0	3	0	3
Acetylcholinesterase	0	6	1	8
Amine oxidase [flavin-containing] B	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	5	0	5
Vasopressin V2 receptor	0	0	0	2
Serine/threonine-protein kinase mTOR	0	1	0	1
Adenosine receptor A2a	0	2	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	0	2
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	2
Chitotriosidase-1	0	2	0	2
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	3	4
Endochitinase B1	0	2	0	2
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	3
Guanine deaminase	0	1	0	1
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Chain A, Ferritin light chain	7	0	0	7
Vitamin D3 receptor	0	0	1	1
PPM1D protein	7	0	0	7
thioredoxin glutathione reductase	2	0	0	2
Vitamin D-binding protein	0	0	1	1
Androgen receptor	0	3	3	6
Vitamin D3 receptor	0	1	2	4
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	0	1	1
Vitamin D3 receptor	0	0	1	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Transporter	0	3	0	3
Vitamin D3 receptor A	0	0	2	2
acetylcholinesterase	11	0	0	11
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	15	0	0	15
Vpr	2	0	0	2
Major prion protein	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	4	0	7
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	2	0	2
MBT domain-containing protein 1	0	1	0	1
Solute carrier family 22 member 1	0	5	0	6
Lethal(3)malignant brain tumor-like protein 4	0	1	0	1
Lethal(3)malignant brain tumor-like protein 3	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Solute carrier family 22 member 2	0	4	0	4
Lethal(3)malignant brain tumor-like protein 1	0	1	0	1
5-hydroxytryptamine receptor 3E	0	2	0	2
vitamin D (1,25- dihydroxyvitamin D3) receptor	18	0	0	18
potassium voltage-gated channel subfamily H member 2 isoform d	10	0	0	10
5-hydroxytryptamine receptor 3B	0	2	0	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
5-hydroxytryptamine receptor 1A	0	7	4	11
Dipeptidyl peptidase 4	0	2	0	2
Insulin receptor	0	1	0	1
D	0	6	0	6
Gastrin/cholecystokinin type B receptor	0	2	0	2
5-hydroxytryptamine receptor 7	0	4	1	5
5-hydroxytryptamine receptor 3A	0	2	0	2
5-hydroxytryptamine receptor 4	0	1	1	2
Neutral alpha-glucosidase AB	0	1	0	1
5-hydroxytryptamine receptor 3D	0	2	0	2
5-hydroxytryptamine receptor 2A	0	1	0	1
5-hydroxytryptamine receptor 3C	0	2	0	2
Heparanase	0	0	1	1
NPC intracellular cholesterol transporter 1 precursor	6	0	0	6
Sodium-dependent noradrenaline transporter	0	3	0	3
Tryptophan 5-hydroxylase 1	0	2	0	2
Aldo-keto reductase family 1 member B1	0	4	0	4
Aromatase	0	1	0	1
Sodium-dependent serotonin transporter	0	3	0	3
Sodium-dependent dopamine transporter	0	3	0	3
Transporter	0	7	0	7
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	4	0	0	4
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
perilipin-5	0	2	0	2
perilipin-1	0	2	0	2
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	2	0	2
Beta-lactamase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	0	0	1
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Fumarate hydratase	8	0	0	8
caspase 7, apoptosis-related cysteine protease	7	0	0	7
polyprotein	8	0	0	8
caspase-3	7	0	0	7
Spike glycoprotein	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
cellular tumor antigen p53 isoform a	6	0	0	6
Transmembrane protease serine 2	0	0	2	2
Procathepsin L	0	1	2	3
Replicase polyprotein 1a	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Trypanothione reductase	0	2	0	2
Trypanothione reductase	0	1	0	1
Proteasome subunit alpha type-6	0	0	1	1
Envelope glycoprotein	0	0	3	3
Angiotensin-converting enzyme 2	0	0	2	2
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	2	0	0	2
Gamma-aminobutyric acid receptor subunit pi	0	4	0	4
Gamma-aminobutyric acid receptor subunit delta	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	5	1	6
Gamma-aminobutyric acid receptor subunit beta-1	0	4	1	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	5	1	6
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	5	1	6
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-3	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-2	0	4	1	5
Gamma-aminobutyric acid receptor subunit beta-2	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-4	0	4	1	5
Gamma-aminobutyric acid receptor subunit epsilon	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	4	1	5
Gamma-aminobutyric acid receptor subunit gamma-1	0	4	0	4
Gamma-aminobutyric acid receptor subunit gamma-3	0	4	0	4
Gamma-aminobutyric acid receptor subunit theta	0	4	0	4
Alpha-1B adrenergic receptor	0	0	3	3
cytochrome P450 2C9 precursor	6	0	0	6
Membrane primary amine oxidase	0	1	0	1
5-hydroxytryptamine receptor 3A	0	0	1	1
Solute carrier family 22 member 3	0	2	0	2
Alpha-1A adrenergic receptor	0	4	3	7
D(3) dopamine receptor	0	7	0	7
D(1B) dopamine receptor	0	3	0	3
Alpha-2B adrenergic receptor	0	1	0	3
D(4) dopamine receptor	0	4	0	4
Alpha-2C adrenergic receptor	0	1	0	3
Alpha-2A adrenergic receptor	0	1	0	3
Alpha-2A adrenergic receptor	0	1	0	1
Nischarin	0	2	0	2
Nischarin	0	2	0	2
SMAD family member 2	10	0	0	10
SMAD family member 3	10	0	0	10
Aldo-keto reductase family 1 member B10	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Cytochrome c oxidase subunit 2	0	2	0	2
Transthyretin	0	0	1	3
Albumin	0	2	3	5
Interleukin-8	0	2	0	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Fatty acid-binding protein, intestinal	0	1	0	1
Aldo-keto reductase family 1 member B1	0	3	0	3
Sodium- and chloride-dependent GABA transporter 1	0	3	0	3
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	3	0	3
Sodium- and chloride-dependent GABA transporter 3	0	3	0	3
Prostaglandin G/H synthase 2	0	2	0	2
UDP-glucuronosyltransferase 2B10	0	3	0	3
Sodium- and chloride-dependent betaine transporter	0	3	0	3
Prostaglandin G/H synthase 2	0	3	0	3
Prostaglandin G/H synthase 2	0	2	0	3
Solute carrier family 22 member 6	0	2	0	2
Prostaglandin G/H synthase 1	0	2	0	2
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
interleukin 8	4	0	0	4
PAX8	0	0	0	1
STAT3, partial	0	1	0	1
67.9K protein	7	0	0	7
tumor necrosis factor	2	0	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	3
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-1	0	2	0	2
Integrin beta-3	3	0	0	3
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
ATP-dependent translocase ABCB1	0	4	0	4
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
ATP-dependent translocase ABCB1	0	18	1	24
Integrin alpha-IIb	3	0	0	3
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
ATP-dependent translocase ABCB1	0	4	0	4
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
ATPase family AAA domain-containing protein 5	9	0	0	9
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Solute carrier organic anion transporter family member 1B3	0	3	0	3
Solute carrier organic anion transporter family member 1B1	0	3	0	3
Caspase-7	3	0	0	3
caspase-3	3	0	0	3
Solute carrier family 22 member 2	0	3	0	3
Multidrug and toxin extrusion protein 2	0	3	0	3
Chain A, Putative fructose-1,6-bisphosphate aldolase	5	0	0	5
endonuclease IV	3	0	0	3
15-lipoxygenase, partial	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
Caspase-7	2	0	0	2
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
acid sphingomyelinase	2	0	0	2
RGS12	1	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
hypoxia-inducible factor 1 alpha subunit	6	0	0	6
DNA polymerase III, partial	2	0	0	2
isocitrate dehydrogenase 1, partial	1	0	0	1
nonstructural protein 1	7	0	0	7
LANA	0	0	0	1
bromodomain adjacent to zinc finger domain 2B	6	0	0	6
thyrotropin-releasing hormone receptor	2	0	0	2
serine-protein kinase ATM isoform a	1	0	0	1
peripheral myelin protein 22 isoform 1	5	0	0	5
heat shock protein beta-1	6	0	0	6
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
importin subunit beta-1 isoform 1	3	0	0	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
serine/threonine-protein kinase PLK1	2	0	0	2
eyes absent homolog 2 isoform a	2	0	0	2
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
snurportin-1	3	0	0	3
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	3	0	0	3
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
caspase-1 isoform alpha precursor	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
kelch-like ECH-associated protein 1	0	0	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	2	0	2
Multidrug resistance-associated protein 5	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	2	0	2
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	4	0	4
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	3	0	3
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	2	0	2
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	3	0	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	3	0	3
Exopolyphosphatase PRUNE1	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Single-stranded DNA cytosine deaminase	1	0	0	1
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	5	0	0	5
mu-type opioid receptor isoform MOR-1	0	0	1	1
huntingtin isoform 2	2	0	0	2
5-hydroxytryptamine receptor 2A	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Acetylcholinesterase	0	3	0	3
galanin receptor type 3	0	1	0	1
D(3) dopamine receptor isoform e	1	0	0	1
D(4) dopamine receptor	0	6	0	6
Kappa-type opioid receptor	0	2	2	4
Mu-type opioid receptor	0	2	0	3
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Cytochrome P450 1B1	0	1	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	0	1	1
Alpha-synuclein	3	0	0	3
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Chain A, ACETYLCHOLINESTERASE	0	1	0	1
Chain A, Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	2	0	2
Acetylcholinesterase	0	2	0	2
Vascular endothelial growth factor receptor 1	0	1	0	1
Acetylcholinesterase	0	1	0	1
Vascular endothelial growth factor receptor 3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Acetylcholinesterase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Small conductance calcium-activated potassium channel protein 3	0	1	0	1
Carboxylic ester hydrolase	0	2	0	2
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Glutamine synthetase	0	1	0	1
Cytochrome P450 71B1	0	1	0	2
Glutamine synthetase	0	1	0	1
2-dehydro-3-deoxyphosphooctonate aldolase	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	2	0	3
Mas-related G-protein coupled receptor member X2	0	0	2	2
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Parkin	4	0	0	4
M-phase phosphoprotein 8	5	0	0	5
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin E synthase	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	2
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Phospholipase A2, major isoenzyme	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Thromboxane-A synthase	0	3	0	3
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Caspase-1	0	0	0	1
Substance-P receptor	0	2	0	2
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Aldo-keto reductase family 1 member C3	0	3	0	3
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	2	0	2
Prostaglandin D2 receptor	0	2	0	2
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	2	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Beta-2 adrenergic receptor	0	4	1	7
Beta-2 adrenergic receptor	0	0	1	1
Beta-adrenergic receptor kinase 1	0	1	2	3
Beta-3 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	3	1	4
Glutamate receptor ionotropic, NMDA 1	0	0	1	1
Taste receptor type 2 member 38	0	0	1	1
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Glutamate receptor ionotropic, NMDA 2A	0	0	1	1
Glutamate receptor ionotropic, NMDA 2C	0	0	1	1
Beta-2 adrenergic receptor	0	1	1	2
Glutamate receptor ionotropic, NMDA 2D	0	0	1	1
Taste receptor type 2 member 42	0	0	1	1
Glutamate receptor ionotropic, NMDA 3B	0	0	1	1
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	1	1
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
Glutamate receptor ionotropic, NMDA 3A	0	0	1	1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2	0	0	1	1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1	0	0	1	1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4	0	0	1	1
Potassium voltage-gated channel subfamily A member 5	0	3	0	3
Potassium voltage-gated channel subfamily D member 2	0	2	0	2
Potassium channel subfamily K member 18	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
pregnane X receptor	4	0	0	4
PINK1	1	0	0	1
transcriptional regulator ERG isoform 3	5	0	0	5
Estrogen receptor	0	3	2	6
Glucocorticoid receptor	0	4	1	5
Progesterone receptor	0	3	1	4
Glycine receptor subunit alpha-1	0	4	0	4
Androgen receptor	0	0	1	1
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
Estrogen receptor beta	0	3	2	5
Histidine decarboxylase	0	0	1	1
Kappa-type opioid receptor	0	1	0	2
UDP-glucuronosyltransferase 1A8	0	0	0	2
Neuropeptide Y receptor type 1	0	2	0	2
Neuropeptide Y receptor type 2	0	2	0	2
hypothetical protein, conserved	1	0	0	1
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Glutathione reductase, mitochondrial	0	2	0	2
Phospholipase A2, membrane associated	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Platelet-activating factor receptor	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
C-C chemokine receptor type 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Leukotriene B4 receptor 1	0	0	0	1
Myosin light chain kinase, smooth muscle	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Potassium channel subfamily K member 2	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Sodium/iodide cotransporter	0	1	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Histamine H1 receptor	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
Neutrophil elastase	0	1	0	1
Proteinase-activated receptor 1	0	1	0	1
Nitric oxide synthase, endothelial	0	2	0	2
Collagenase 3	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
Myeloperoxidase	0	1	0	1
Quinolone resistance protein NorA	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Substance-P receptor	0	5	1	6
Rhodopsin kinase GRK1	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
Rhodopsin kinase GRK1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	0	1
ClpP	2	0	0	2
Hsf1 protein	0	0	1	1
estrogen receptor beta isoform 1	0	1	0	1
Alpha-1A adrenergic receptor	0	1	2	3
Alpha-1B adrenergic receptor	0	4	0	4
Gamma-aminobutyric acid	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
5-hydroxytryptamine receptor 1B	0	3	1	4
Angiotensin-converting enzyme	0	1	0	1
heat shock protein 90, putative	0	0	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
Neuromedin-K receptor	0	0	1	1
Cholecystokinin receptor type A	0	1	1	2
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Pyridoxal kinase	0	0	0	1
Histidine-rich protein PFHRP-II	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Cytochrome P450 2D4	0	1	0	1
Multidrug resistance protein 1a	0	0	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Transcriptional activator protein LuxR	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Melanocortin receptor 5	0	4	0	4
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-K receptor	0	4	0	4
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Chain A, CES1 protein	0	1	0	1
apical membrane antigen 1, AMA1	1	0	0	1
interferon gamma precursor	0	0	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
streptokinase A precursor	0	0	2	2
Serine/threonine-protein kinase D3	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Estrogen receptor	0	0	1	2
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Steroid hormone receptor ERR1	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C eta type	0	1	0	1
B2 bradykinin receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Protein kinase C iota type	0	1	0	1
Melanocortin receptor 3	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C theta type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Serine/threonine-protein kinase D1	0	1	0	1
Estrogen receptor beta	0	0	1	2
Protein kinase C eta type	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Phosphodiesterase	0	2	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	2	0	2
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Cocaine esterase	0	1	0	1
Histone deacetylase 3	0	2	0	2
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Liver carboxylesterase 1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Histone deacetylase 4	0	2	0	2
Histone deacetylase 1	0	2	0	2
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	2	0	2
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Histone deacetylase 8	0	2	0	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
POsterior Segregation	0	0	1	1
Estrogen receptor beta	0	1	0	1
DNA topoisomerase 1	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Estrogen receptor	0	1	0	1
M-phase inducer phosphatase 1	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Zinc finger protein mex-5	0	0	1	1
twin arginine protein translocation system - TatA protein	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Protein-arginine deiminase type-4	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(9)

Research Excerpts

Overview

Context

Treatment

Research

Studies (562)

Protein Targets (1,228)

Neurally Mediated Faint

Synonyms(9)

Research Excerpts

Overview

Context

Treatment

Research

Studies (562)

Drugs Studied (164)

Protein Targets (1,228)