Page last updated: 2024-09-28

Burnout, Professional

An excessive stress reaction to one's occupational or professional environment. It may be characterized by feelings of emotional and physical exhaustion, coupled with a sense of frustration and failure.

Synonyms(3)

Synonym
Career Burnout
Occupational Burnout
Burnout, Professional

Research Excerpts

Overview

ExcerptReference
"Occupational burnout is both a serious health concern at both public and individual levels."( Abbasalipourkabir, R; Ahmadpanah, M; Brand, S; Faryadras, M; Haghighi, M; Hedayati, M; Jahangard, L; Mikoteit, T; Sadeghi Bahmani, D, 2019)

Context

ExcerptReference
"Occupational burnout has been associated with an increased risk of cardiovascular disease, with sympathetic nervous system (SNS) dysfunction as one explanation."( Gomez Vieito, D; Holzgang, SA; Pazhenkottil, AP; Princip, M; Sivakumar, S; von Känel, R; Zuccarella-Hackl, C, 2023)

Research

Studies (414)

TimeframeStudies, This Condition (%)All Conditions %
pre-19908 (1.93)23.3326
1990's34 (8.21)12.5806
2000's83 (20.05)18.1394
2010's172 (41.55)28.8240
2020's117 (28.26)9.53
DrugIndicatedRelationship StrengthStudiesTrials
glycerol0low10
nickel0low10
niacinamide0medium11
nitrites0low10
nitrous oxide0low10
taurine0medium11
vanilmandelic acid0low10
3,4-methylenedioxyamphetamine0low40
aspirin0low10
caffeine0low20
pantogab0low10
fentanyl0low10
flumazenil0low10
glyphosate0low10
lidocaine0low10
thyroxine0low20
aldosterone0medium11
triiodothyronine0low10
aspartic acid0low10
glutamine0low10
sucrose0low10
phenylephrine0low10
valine0low10
phencyclidine0low30
propylene glycol methyl ether0low10
chlorfenvinphos0low10
malondialdehyde0low10
dehydroepiandrosterone sulfate0medium63
s,n,n'-tripropylthiocarbamate0medium741
cetylpyridinium chloride anhydrous0low130
pregnanolone0low10
4-methoxyamphetamine0medium241
glutamic acid0low10
fenoxycarb0low10
n-acetylaspartic acid0low10
fibrinogen0low20
homocysteine0low10
mebikar0medium11
cortisone0low10
glycogen0low10
oxytocin0medium11
cocaine0low10
cannabidiol0low10
capsaicin0medium11
freedom0low20
alprostadil0low10
naloxone0low10
psycholeine0low10
chlorhexidine0low10
bicyclo(2.2.1)hept-5-en-2-yl phenyl sulfoxide0low10
buprenorphine, naloxone drug combination0low10
enerbol0low10
clove0low10
baricitinib0low10
interleukin-80medium21
epidermal growth factor0low10
rome0low70
flavin mononucleotide0medium11
muramidase0low10
exudates0low180
inosine diphosphate0medium11
ego0medium31

Protein Targets (944)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
5-hydroxytryptamine receptor 2C0426
5-hydroxytryptamine receptor 2A0437
5-hydroxytryptamine receptor 1A0325
Sodium-dependent noradrenaline transporter 0505
Sodium-dependent dopamine transporter0415
5-hydroxytryptamine receptor 1B0224
5-hydroxytryptamine receptor 1D0224
5-hydroxytryptamine receptor 1F0224
5-hydroxytryptamine receptor 2B0426
5-hydroxytryptamine receptor 60123
Sodium-dependent serotonin transporter0527
Sodium-dependent serotonin transporter0719
5-hydroxytryptamine receptor 7 0123
5-hydroxytryptamine receptor 5A0123
5-hydroxytryptamine receptor 5B0123
5-hydroxytryptamine receptor 3A0123
Sodium-dependent dopamine transporter 0606
5-hydroxytryptamine receptor 4 0123
5-hydroxytryptamine receptor 3B0123
AR protein160016
glucocorticoid receptor [Homo sapiens]110011
thyroid hormone receptor beta isoform a7007
nuclear factor erythroid 2-related factor 2 isoform 24004
geminin110011
Sex hormone-binding globulin0022
Corticosteroid-binding globulin0202
Mineralocorticoid receptor 0123
Androgen receptor0101
Mineralocorticoid receptor0101
Solute carrier organic anion transporter family member 1A10002
Guanine nucleotide-binding protein G1001
TDP1 protein110011
estrogen nuclear receptor alpha200020
peroxisome proliferator activated receptor gamma8008
ATP-binding cassette sub-family C member 30606
Multidrug resistance-associated protein 40709
Bile salt export pump0909
Cellular tumor antigen p538008
Thromboxane-A synthase 0101
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP1 subtype0101
Prostacyclin receptor0112
Nuclear receptor subfamily 4 group A member 20011
Solute carrier organic anion transporter family member 2A10001
Nuclear receptor subfamily 4 group A member 20011
Nuclear receptor subfamily 4 group A member 20011
Prostaglandin E2 receptor EP2 subtype0112
Canalicular multispecific organic anion transporter 10606
Solute carrier organic anion transporter family member 2A10001
Solute carrier organic anion transporter family member 2B10101
Solute carrier organic anion transporter family member 3A10001
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE9009
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain A, Ferritin light chain2002
phosphopantetheinyl transferase6006
aldehyde dehydrogenase 1 family, member A17007
arylsulfatase A4004
euchromatic histone-lysine N-methyltransferase 2140014
Bloom syndrome protein isoform 16006
cytochrome P450 2C19 precursor4004
lethal factor (plasmid)4004
lamin isoform A-delta109009
Metabotropic glutamate receptor 60124
Excitatory amino acid transporter 40202
Glutamate transporter homolog0011
Carbonic anhydrase 10407
Carbonic anhydrase 20519
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
5-hydroxytryptamine receptor 1D0001
Glutamate receptor ionotropic, NMDA 1 0617
Excitatory amino acid transporter 10304
Excitatory amino acid transporter 20304
Excitatory amino acid transporter 30304
Glutamate receptor ionotropic, NMDA 2A 0617
Glutamate receptor ionotropic, NMDA 2B0617
Glutamate receptor ionotropic, NMDA 2C0618
Metabotropic glutamate receptor 10124
Metabotropic glutamate receptor 20124
Carbonic anhydrase-like protein, putative0003
Glutamate receptor ionotropic, NMDA 2D0617
Glutamate receptor ionotropic, NMDA 3B0617
Carbonic anhydrase 40001
Glutamate receptor ionotropic, NMDA 3A0617
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein3003
Chain B, HADH2 protein3003
Chain A, 2-oxoglutarate Oxygenase1001
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 82002
thioredoxin reductase8008
GLS protein8008
thyroid stimulating hormone receptor4004
hypothetical protein, conserved1001
cytochrome P450 family 3 subfamily A polypeptide 46006
EWS/FLI fusion protein6006
retinoic acid nuclear receptor alpha variant 1110011
estrogen-related nuclear receptor alpha120012
cytochrome P450 2D64004
glucocerebrosidase5005
peroxisome proliferator-activated receptor delta8008
Rac1 protein0011
IDH14004
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
DNA polymerase iota isoform a (long)2002
DNA polymerase kappa isoform 16006
muscarinic acetylcholine receptor M15005
Prostaglandin-H2 D-isomerase0101
Solute carrier family 22 member 60101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Epidermal growth factor receptor0112
Fatty acid-binding protein, liver0101
Integrin beta-31113
Myeloperoxidase0101
Prostaglandin G/H synthase 10101
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb1113
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10303
Adenosine receptor A10304
Adenosine receptor A2a0305
Substance-P receptor0101
Prostaglandin G/H synthase 20202
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma3003
Ras-related protein Rab-2A0011
Gamma-aminobutyric acid receptor subunit alpha-14419
Prostaglandin G/H synthase 20101
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Sigma non-opioid intracellular receptor 10617
Sigma non-opioid intracellular receptor 10415
PPM1D protein2002
Bone morphogenetic protein receptor type-1B0011
Membrane-associated progesterone receptor component 10011
Serine/threonine-protein kinase PLK40011
ATP-dependent RNA helicase DDX3X0011
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase Chk10011
Aurora kinase A0011
Cyclin-G-associated kinase0112
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Receptor-interacting serine/threonine-protein kinase 20011
Dynamin-like 120 kDa protein, mitochondrial0011
Tyrosine-protein kinase JAK20102
Eukaryotic translation initiation factor 5B0011
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30011
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
Tyrosine-protein kinase ABL10011
Interferon beta5005
Guanine nucleotide-binding protein G(i) subunit alpha-20011
ADP/ATP translocase 20011
Protein kinase C beta type0011
Insulin receptor0011
Tyrosine-protein kinase Lck0011
Tyrosine-protein kinase Fyn0011
Cyclin-dependent kinase 10011
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0011
Tyrosine-protein kinase Lyn0011
Proto-oncogene tyrosine-protein kinase receptor Ret0011
Insulin-like growth factor 1 receptor0011
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0011
Platelet-derived growth factor receptor beta0011
Serine/threonine-protein kinase A-Raf0011
Glycogen phosphorylase, brain form0011
Breakpoint cluster region protein0011
Serine/threonine-protein kinase pim-10011
Fibroblast growth factor receptor 10011
DNA topoisomerase 2-alpha0011
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
Inosine-5'-monophosphate dehydrogenase 20011
Proto-oncogene tyrosine-protein kinase Src0011
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Serine/threonine-protein kinase B-raf0011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Ribosyldihydronicotinamide dehydrogenase [quinone]0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0011
cAMP-dependent protein kinase catalytic subunit alpha0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Casein kinase II subunit alpha'0011
Ras-related protein Rab-6A0011
Ephrin type-A receptor 10011
Multifunctional protein ADE20011
cAMP-dependent protein kinase catalytic subunit gamma0011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0011
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10113
Cyclin-dependent kinase 20011
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Deoxycytidine kinase0011
Mitogen-activated protein kinase 10011
Ephrin type-A receptor 20011
Ephrin type-B receptor 20011
Non-receptor tyrosine-protein kinase TYK20113
UMP-CMP kinase 0011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-alpha serine/threonine-protein kinase0011
RAC-beta serine/threonine-protein kinase0011
DNA replication licensing factor MCM40011
Myosin-100011
Dual specificity mitogen-activated protein kinase kinase 20011
Receptor-type tyrosine-protein kinase FLT30011
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
Serine/threonine-protein kinase receptor R30011
TGF-beta receptor type-20011
Electron transfer flavoprotein subunit beta0011
Tyrosine-protein kinase CSK0011
Glycine--tRNA ligase0011
Protein kinase C iota type0011
Exosome RNA helicase MTR40011
Tyrosine-protein kinase Tec0011
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0011
G protein-coupled receptor kinase 60011
Tyrosine-protein kinase SYK0011
26S proteasome regulatory subunit 6B0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 30011
Casein kinase I isoform alpha0011
Casein kinase I isoform delta0011
MAP kinase-activated protein kinase 20011
Elongation factor Tu, mitochondrial0011
Cysteine--tRNA ligase, cytoplasmic0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Dual specificity protein kinase CLK30011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Tyrosine-protein kinase JAK30102
Dual specificity mitogen-activated protein kinase kinase 60011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
5'-AMP-activated protein kinase subunit gamma-10011
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Adenosine kinase0011
Ras-related protein Rab-100011
Actin-related protein 30011
Actin-related protein 20011
GTP-binding nuclear protein Ran0011
Casein kinase I isoform gamma-20011
Cyclin-dependent kinase 30011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
ATP-dependent 6-phosphofructokinase, platelet type0011
Dual specificity mitogen-activated protein kinase kinase 10011
DNA topoisomerase 2-beta0011
Protein kinase C theta type0011
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Protein kinase C delta type0011
Tyrosine-protein kinase BTK0011
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Mitogen-activated protein kinase kinase kinase kinase 20011
Serine/threonine-protein kinase 40011
5'-AMP-activated protein kinase catalytic subunit alpha-10011
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
Integrin-linked protein kinase0011
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Serine/threonine-protein kinase ATR0112
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60011
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Peroxisomal acyl-coenzyme A oxidase 10011
Ephrin type-A receptor 70011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10011
Dual specificity testis-specific protein kinase 10011
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110011
Serine/threonine-protein kinase STK110011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Mitogen-activated protein kinase 140011
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
MAP kinase-activated protein kinase 30011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10112
Myosin light chain kinase 30011
Uncharacterized aarF domain-containing protein kinase 50011
Putative heat shock protein HSP 90-beta 20011
Rab-like protein 30011
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase ULK30011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
ATP-dependent RNA helicase DHX300011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
ATP-dependent RNA helicase DDX420011
Mitogen-activated protein kinase kinase kinase kinase 30011
MAP kinase-activated protein kinase 50011
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0011
Misshapen-like kinase 10011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
ATP-dependent RNA helicase DDX10011
Mitogen-activated protein kinase kinase kinase kinase 10011
Aurora kinase B0011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase Nek10011
PAS domain-containing serine/threonine-protein kinase0011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
NUAK family SNF1-like kinase 20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase PAK 60011
Phenylalanine--tRNA ligase beta subunit0011
Isoleucine--tRNA ligase, mitochondrial0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Mitogen-activated protein kinase kinase kinase 200011
Cyclin-dependent kinase 120011
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130011
Serine/threonine-protein kinase 260011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
5'-AMP-activated protein kinase subunit gamma-20011
Serine/threonine-protein kinase TBK10011
Septin-90011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase TAO20011
Long-chain-fatty-acid--CoA ligase 50011
Serine/threonine-protein kinase ICK0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase 38-like0011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
RAR-related orphan receptor gamma100010
GLI family zinc finger 39009
nuclear receptor subfamily 1, group I, member 38008
retinoid X nuclear receptor alpha8008
farnesoid X nuclear receptor6006
pregnane X nuclear receptor110011
thyroid stimulating hormone receptor3003
v-jun sarcoma virus 17 oncogene homolog (avian)7007
atrial natriuretic peptide receptor 1 precursor3003
chromobox protein homolog 15005
thyroid hormone receptor beta isoform 2100010
DNA polymerase beta1001
nuclear factor erythroid 2-related factor 2 isoform 1100010
nuclear receptor ROR-gamma isoform 16006
Voltage-dependent calcium channel gamma-2 subunit5005
Potassium channel subfamily K member 20112
Glycogen phosphorylase, muscle form0101
Renin0101
Cholinesterase0101
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0101
Adenosine receptor A30101
Replicase polyprotein 1ab0101
Glutamate receptor 25218
Amine oxidase [flavin-containing] A0202
Acetylcholinesterase0202
Amine oxidase [flavin-containing] B0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0202
Adenosine receptor A30101
Adenosine receptor A2a0214
Adenosine receptor A2b0102
Adenosine receptor A2b0203
Adenosine receptor A10417
Vasopressin V2 receptor0001
Serine/threonine-protein kinase mTOR0101
Adenosine receptor A2a0101
Adenosine receptor A10101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10101
Serine-protein kinase ATM0101
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0123
Endochitinase B10101
Muscarinic acetylcholine receptor0001
Phosphodiesterase 0101
Broad substrate specificity ATP-binding cassette transporter ABCG20101
Guanine deaminase0101
ATP-dependent phosphofructokinase4004
Acetylcholinesterase0101
L-lactate dehydrogenase A chain0101
Cytochrome P450 1A10101
Cytochrome P450 1A20202
Cytochrome P450 2C11 0101
Cytochrome P450 3A40101
5-hydroxytryptamine receptor 1A0011
Cytochrome P450 2D60202
Cytochrome P450 2A60101
Cytochrome P450 2C9 0202
Steroid 17-alpha-hydroxylase/17,20 lyase 0101
Fatty acid-binding protein, liver0101
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0213
Cannabinoid receptor 10101
Cytochrome P450 2B60303
Cytochrome P450 3A50202
Cannabinoid receptor 10203
D(1A) dopamine receptor0101
Cytochrome P450 3A70101
5-hydroxytryptamine receptor 2C0101
Caspase-10011
Cytochrome P450 2C190202
Cannabinoid receptor 2 0214
Mu-type opioid receptor07210
Peroxisome proliferator-activated receptor gamma0055
Delta-type opioid receptor0618
Kappa-type opioid receptor0629
Spike glycoprotein3003
Cholinesterase0101
N-acylethanolamine-hydrolyzing acid amidase0101
Cytochrome P450 1B10101
Heat sensitive channel TRPV30112
Sigma intracellular receptor 20101
Transient receptor potential cation channel subfamily A member 10112
Transient receptor potential cation channel subfamily V member 10326
Transient receptor potential cation channel subfamily M member 80101
Transient receptor potential cation channel subfamily V member 40123
Transient receptor potential cation channel subfamily V member 20123
G-protein coupled receptor 550011
Diacylglycerol lipase-alpha0101
Histamine H3 receptor0101
15-lipoxygenase, partial3003
Microtubule-associated protein tau3003
estrogen receptor 2 (ER beta)4004
progesterone receptor7007
67.9K protein4004
vitamin D (1,25- dihydroxyvitamin D3) receptor5005
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a6006
mitogen-activated protein kinase 15005
peripheral myelin protein 224004
survival motor neuron protein isoform d4004
cytochrome P450 3A4 isoform 14004
transient receptor potential cation channel subfamily V member 11001
Gamma-aminobutyric acid receptor subunit pi4318
Transient receptor potential cation channel subfamily V member 10213
Lysine-specific histone demethylase 1A0101
NADH-ubiquinone oxidoreductase chain 10101
Polyunsaturated fatty acid 5-lipoxygenase0101
Gamma-aminobutyric acid receptor subunit beta-14318
Gamma-aminobutyric acid receptor subunit delta4318
Gamma-aminobutyric acid receptor subunit gamma-24318
Gamma-aminobutyric acid receptor subunit alpha-54318
Gamma-aminobutyric acid receptor subunit alpha-34318
Gamma-aminobutyric acid receptor subunit gamma-14318
Gamma-aminobutyric acid receptor subunit alpha-24318
Gamma-aminobutyric acid receptor subunit alpha-44318
Gamma-aminobutyric acid receptor subunit gamma-34318
Gamma-aminobutyric acid receptor subunit alpha-64318
D(2) dopamine receptor0112
Gamma-aminobutyric acid receptor subunit beta-34318
Gamma-aminobutyric acid receptor subunit beta-24318
Inositol monophosphatase 12002
Potassium voltage-gated channel subfamily A member 10112
Corticotropin-releasing factor receptor 20101
GABA theta subunit4318
Gamma-aminobutyric acid receptor subunit epsilon4318
acetylcholinesterase2002
hypoxia-inducible factor 1 alpha subunit3003
SMAD family member 22002
USP1 protein, partial4004
SMAD family member 32002
caspase 7, apoptosis-related cysteine protease2002
caspase-32002
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
activating transcription factor 66006
thyrotropin-releasing hormone receptor1001
vitamin D3 receptor isoform VDRA1001
heat shock protein beta-14004
Caspase-20011
ATPase family AAA domain-containing protein 53003
Ataxin-23003
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Chain A, BCL-2-RELATED PROTEIN A10011
Chain A, Cruzipain3003
Luciferase4004
acid sphingomyelinase1001
PAX80001
glp-1 receptor, partial4004
pregnane X receptor4004
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
PINK11001
G3003
Parkin1001
heat shock protein 900011
calcineurin A1, putative0011
aryl hydrocarbon receptor6006
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a4004
Histone H2A.x2002
cytochrome P450 2D6 isoform 12002
hepatocyte nuclear factor 4-alpha isoform 20101
cellular tumor antigen p53 isoform a1001
cytochrome P450 2C9 precursor1001
perilipin-50101
perilipin-10101
potassium voltage-gated channel subfamily H member 2 isoform d2002
transcriptional regulator ERG isoform 32002
huntingtin isoform 21001
importin subunit beta-1 isoform 11001
ubiquitin-conjugating enzyme E2 N0101
nuclear factor NF-kappa-B p105 subunit isoform 11001
flap endonuclease 16006
protein AF-9 isoform a0001
snurportin-11001
melanocortin receptor 40101
CAAX prenyl protease0001
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
bcl-2-related protein A10101
urokinase plasminogen activator surface receptor precursor1001
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
glycogen synthase kinase-3 alpha0001
hexokinase HKDC10101
DNA repair protein RAD52 homolog isoform a0001
bcl-2-like protein 11 isoform 10011
Synaptojanin-20101
Solute carrier family 22 member 20101
Solute carrier family 22 member 1 0202
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Synaptojanin-10101
Solute carrier family 22 member 30101
Glutathione reductase, mitochondrial0304
HLA class I histocompatibility antigen, B alpha chain 3003
72 kDa type IV collagenase0101
Matrix metalloproteinase-90101
Trypanothione reductase0101
Alpha-synuclein1001
Histamine H2 receptor1001
TAR DNA-binding protein 433003
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase0101
Multidrug and toxin extrusion protein 20101
Rap guanine nucleotide exchange factor 42002
Inositol hexakisphosphate kinase 13003
Multidrug and toxin extrusion protein 10303
Spermine oxidase0101
cytochrome P450 2C9, partial3003
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0303
Gamma-aminobutyric acid receptor subunit delta0303
Amyloid-beta precursor protein0101
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M10213
Tryptophan 5-hydroxylase 10101
Gamma-aminobutyric acid receptor subunit alpha-10314
Gamma-aminobutyric acid receptor subunit beta-10303
Gamma-aminobutyric acid receptor subunit gamma-20314
D0101
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
Alpha-2A adrenergic receptor0202
Liver carboxylesterase 10001
Gamma-aminobutyric acid receptor subunit beta-30314
Gamma-aminobutyric acid receptor subunit alpha-50314
Gamma-aminobutyric acid receptor subunit alpha-30314
Lysosomal Pro-X carboxypeptidase0202
Gamma-aminobutyric acid receptor subunit alpha-20303
Gamma-aminobutyric acid receptor subunit beta-20303
Gamma-aminobutyric acid receptor subunit alpha-40303
Gamma-aminobutyric acid receptor subunit epsilon0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Potassium voltage-gated channel subfamily H member 20505
Leukotriene B4 receptor 10101
Gamma-aminobutyric acid receptor subunit alpha-60303
Sodium-dependent dopamine transporter0202
Gamma-aminobutyric acid receptor subunit gamma-10303
Gamma-aminobutyric acid receptor subunit gamma-30303
Leukotriene B4 receptor 20101
Gamma-aminobutyric acid receptor subunit theta0303
Transporter0404
endonuclease IV2002
dopamine D1 receptor2002
regulator of G-protein signaling 44004
peripheral myelin protein 22 isoform 12002
M-phase phosphoprotein 81001
Glucocorticoid receptor0202
Glycine receptor subunit alpha-10202
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Solute carrier organic anion transporter family member 1A40104
Solute carrier organic anion transporter family member 1A50003
Steryl-sulfatase0001
Multidrug resistance-associated protein 1 0001
Solute carrier organic anion transporter family member 1A20003
Solute carrier organic anion transporter family member 1A30003
G-protein coupled bile acid receptor 10011
ATP-binding cassette sub-family C member 110001
Solute carrier organic anion transporter family member 1B30002
Solute carrier family 22 member 110001
Solute carrier organic anion transporter family member 1A10001
Solute carrier organic anion transporter family member 1B20001
Solute carrier organic anion transporter family member 1B10003
Nuclear receptor subfamily 1 group I member 20022
ATP-dependent translocase ABCB10202
D(2) dopamine receptor0303
D(4) dopamine receptor0303
Delta-type opioid receptor0417
Delta-type opioid receptor0426
Mu-type opioid receptor0437
Kappa-type opioid receptor0224
Histamine H1 receptor0101
D(3) dopamine receptor0303
Kappa-type opioid receptor0415
Mu-type opioid receptor0204
Mu-type opioid receptor0415
Sigma non-opioid intracellular receptor 10415
muscleblind-like protein 1 isoform 12002
Bile salt export pump0101
Gamma-aminobutyric acid receptor subunit alpha-10203
Gamma-aminobutyric acid receptor subunit beta-10203
Neuronal acetylcholine receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit alpha-20203
Gamma-aminobutyric acid receptor subunit alpha-30203
Neuronal acetylcholine receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40203
Gamma-aminobutyric acid receptor subunit gamma-20203
Neuronal acetylcholine receptor subunit alpha-70101
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
Metabotropic glutamate receptor 80202
Glutamate receptor ionotropic, NMDA 2D0202
Glutamate receptor ionotropic, NMDA 3B0202
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0022
ATP-citrate synthase 0101
Glutamate receptor 10213
Glutamate receptor 30213
Glutamate receptor 40213
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10202
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, NMDA 10303
Glutamate receptor ionotropic, NMDA 2A0303
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Glutamate receptor ionotropic, NMDA 2B0303
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, NMDA 2C0202
Glutamate receptor ionotropic, kainate 50101
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Glutamate receptor ionotropic, NMDA 3A0202
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Chain A, Glutamine Binding Protein0011
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
Neutral amino acid transporter A0101
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0101
Amino acid transporter0101
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase0101
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase0101
Glutamine synthetase 0101
Cytochrome P450 71B10102
Glutamine synthetase 0101
2-dehydro-3-deoxyphosphooctonate aldolase0101
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
Chain A, Beta-lactamase2002
Potassium channel subfamily K member 30101
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 2 subunit alpha0202
Sodium channel protein type 3 subunit alpha0202
Potassium voltage-gated channel subfamily A member 50101
Sodium channel protein type 4 subunit alpha0101
Sodium channel protein type 5 subunit alpha0101
Sodium channel protein type 9 subunit alpha0101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Sodium channel protein type 3 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Mas-related G-protein coupled receptor member X20011
Aldehyde oxidase 1 0101
thioredoxin glutathione reductase2002
Transporter0101
Muscarinic acetylcholine receptor M30112
Muscarinic acetylcholine receptor M40112
Muscarinic acetylcholine receptor M50112
Muscarinic acetylcholine receptor M20112
Histidine decarboxylase0011
D(3) dopamine receptor0101
Kappa-type opioid receptor0103
Cytochrome P450 2J20101
Beta-2 adrenergic receptor0101
UDP-glucuronosyltransferase 1A80001
Chain A, NAD-dependent deacetylase0101
Caspase-71001
caspase-31001
histone acetyltransferase KAT2A isoform 11001
Poly [ADP-ribose] polymerase 20101
NAD-dependent histone deacetylase SIR20101
Coagulation factor VII0101
Poly [ADP-ribose] polymerase 10101
Tissue factor0101
NAD-dependent protein deacetylase HST20101
Protein mono-ADP-ribosyltransferase PARP150101
NAD(+) hydrolase SARM10101
NAD-dependent protein deacetylase sirtuin-20101
NAD-dependent protein deacetylase sirtuin-60101
NAD-dependent protein deacetylase sirtuin-10101
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
NAD-dependent protein deacetylase 0101
Carbonic anhydrase 40101
Carbonic anhydrase0101
Carbonic anhydrase 150101
Vasopressin V2 receptor0112
Oxytocin receptor0224
Vasopressin V1a receptor0101
Vasopressin V1a receptor0213
Vasopressin V1b receptor0112
Vasopressin V1b receptor0101
Oxytocin receptor0101
Oxytocin receptor0011
Vasopressin V2 receptor 0101
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Muscarinic acetylcholine receptor M10012
Muscarinic acetylcholine receptor M40012
Cholinesterase0101
Muscarinic acetylcholine receptor M50012
Muscarinic acetylcholine receptor M30012
Muscarinic acetylcholine receptor M20012
NFKB1 protein, partial1001
Alpha-1B adrenergic receptor 0011
D(1A) dopamine receptor1001
ras-related protein Rab-9A1001
Beta-2 adrenergic receptor0011
Beta-1 adrenergic receptor0011
Alpha-2A adrenergic receptor0112
Beta-3 adrenergic receptor0011
POU domain, class 2, transcription factor 10001
Alpha-1B adrenergic receptor0101
Beta-1 adrenergic receptor0101
Alpha-1A adrenergic receptor0112
Alpha-1B adrenergic receptor0101
Alpha-1D adrenergic receptor0101
Alpha-2B adrenergic receptor0001
Alpha-1A adrenergic receptor0112
Alpha-1B adrenergic receptor0112
Alpha-1A adrenergic receptor0101
Alpha-2C adrenergic receptor0001
Alpha-2A adrenergic receptor0001
Gamma-aminobutyric acid 0011
Gamma-aminobutyric acid receptor subunit alpha-60011
Gamma-aminobutyric acid receptor subunit gamma-20011
Gamma-aminobutyric acid receptor subunit delta0011
Sodium- and chloride-dependent GABA transporter 10101
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit alpha-30011
Gamma-aminobutyric acid receptor subunit gamma-30011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
Gamma-aminobutyric acid receptor subunit beta-10011
Gamma-aminobutyric acid receptor subunit alpha-10112
Gamma-aminobutyric acid receptor subunit beta-30011
Gamma-aminobutyric acid receptor subunit alpha-50011
Gamma-aminobutyric acid receptor subunit pi0011
Gamma-aminobutyric acid receptor subunit alpha-40011
Gamma-aminobutyric acid receptor subunit theta0011
Gamma-aminobutyric acid receptor subunit gamma-10011
Sphingosine kinase 20202
Sphingosine kinase 10101
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
Carbonic anhydrase 90112
GALC protein1001
Sodium- and chloride-dependent taurine transporter0101
Proton-coupled amino acid transporter 10101
Chain X, Thyroid hormone receptor beta-10022
Chain X, Thyroid hormone receptor beta-10022
apical membrane antigen 1, AMA12002
serine/threonine-protein kinase PLK11001
DNA polymerase eta isoform 11001
Rap guanine nucleotide exchange factor 31001
Transthyretin0103
Thyroid hormone receptor alpha0235
Thyroid hormone receptor beta0235
Proliferating cell nuclear antigen0202
Retinoic acid receptor RXR-alpha0022
UDP-glucuronosyltransferase 1A1 0101
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 4C10102
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
neuropeptide S receptor isoform A2002
Androgen receptor0101
Thyroid hormone receptor beta0101
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 4A10001
Solute carrier organic anion transporter family member 1C10101
Chain A, Arginase 10101
Large neutral amino acids transporter small subunit 10101
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]