glyphosate has been researched along with Amyotrophic Lateral Sclerosis in 2 studies
glyphosate: active cpd in herbicidal formulation Roundup; inhibits EC 2.5.1.19, 5-enolpyruvylshikimate-3-phosphate synthase; structure
glyphosate : A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrew, A | 1 |
| Zhou, J | 1 |
| Gui, J | 1 |
| Harrison, A | 1 |
| Shi, X | 1 |
| Li, M | 1 |
| Guetti, B | 1 |
| Nathan, R | 1 |
| Tischbein, M | 1 |
| Pioro, EP | 1 |
| Stommel, E | 1 |
| Bradley, W | 1 |
| Anderson, G | 1 |
1 review available for glyphosate and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Amyotrophic Lateral Sclerosis Pathoetiology and Pathophysiology: Roles of Astrocytes, Gut Microbiome, and Muscle Interactions via the Mitochondrial Melatonergic Pathway, with Disruption by Glyphosate-Based Herbicides.
Topics: Amyotrophic Lateral Sclerosis; Astrocytes; Gastrointestinal Microbiome; Glyphosate; Herbicides; Huma | 2022 |
1 other study available for glyphosate and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Pesticides applied to crops and amyotrophic lateral sclerosis risk in the U.S.
Topics: 2,4-Dichlorophenoxyacetic Acid; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Carbaryl; Ch | 2021 |