Compounds > alpha-phenylcinnamate
Page last updated: 2024-09-28

alpha-phenylcinnamate

Description

alpha-phenylcinnamate: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID700620
CHEMBL ID1980291
MeSH IDM0170819

Synonyms (70)

Synonym
EN300-17442
benzeneacetic acid, .alpha.-(phenylmethylene)-
cinnamic acid, .alpha.-phenyl-
atropic acid, .beta.-phenyl-
.alpha.-phenylcinnamic acid
3368-16-9
2-propenoic acid,3-diphenyl-
acrylic acid,3-diphenyl-
NSC40614 ,
.alpha.-stilbenecarboxylic acid
trans-.alpha.-phenylcinnamic acid
acrylic acid,3-diphenyl-, (e)-
cis-stilbene-.alpha.-carboxylic acid
(e)-.alpha.-stilbenecarboxylic acid
nsc83528
trans-2,3-diphenylpropenoic acid
trans-2,3-diphenylacrylic acid
.alpha.-phenylcinnamic acid (cis-form)
91-48-5
nsc-83528
(e)-2,3-diphenylpropenoic acid
benzeneacetic acid, (e)-
alpha-phenylcinnamic acid
STK298626
(2e)-2,3-diphenylprop-2-enoic acid
alpha-phenylcinnamic acid, 97%
alpha-phenyl-trans-cinnamic acid
2,3-diphenylprop-2-enoic acid
AKOS002286967
(e)-2,3-diphenylprop-2-enoic acid
cis-alpha-phenylcinnamic acid
einecs 202-069-4
alpha-phenylcinnamic acid, (e)-
0pkh62904b ,
nsc 83528
unii-0pkh62904b
BBL009868
(e)-2,3-diphenyl-acrylic acid
bdbm50429337
nsc 40614
alpha-phenylcinnamate
benzeneacetic acid, alpha-(phenylmethylene)-
(e)-2,3-diphenylacrylic acid
CHEMBL1980291 ,
a-phenylcinnamic acid
e-2,3-diphenylpropenoic acid
(2e)-2,3-diphenylacrylic acid
(e)-phenylcinnamic acid
.alpha.-phenylcinnamic acid, (e)-
trans-2,3-diphenyl-2-propenoic acid
(e)-2,3-diphenyl-2-propenoic acid
(e)-.alpha.-phenylcinnamic acid
benzeneacetic acid, .alpha.-(phenylmethylene)-, (e)-
acrylic acid, 2,3-diphenyl-, trans-
.alpha.-phenylcinnamic acid trans-form [mi]
acrylic acid, 2,3-diphenyl-, (e)-
.alpha.-phenylcinnamic acid [mi]
(2e)-2,3-diphenyl-2-propenoic acid #
.alpha.-phenylcinnamic acid (trans-form)
.alpha.,.beta.-diphenyl acrylic acid, trans-
trans-stilbene-.alpha.-carboxylic acid
D92103
(e)-alpha-phenylcinnamic acid
alpha-phenylcinnamicacid
Q4734916
CS-0259613
STR05165
EN300-7372860
DTXSID00871015
Z56934842

Protein Targets (1)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Aldo-keto reductase family 1 member C1Homo sapiens (human)IC50 (µMol)7.90000.00603.12657.9000AID735521
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (16)

Processvia Protein(s)Taxonomy
retinoid metabolic processAldo-keto reductase family 1 member C1Homo sapiens (human)
xenobiotic metabolic processAldo-keto reductase family 1 member C1Homo sapiens (human)
digestionAldo-keto reductase family 1 member C1Homo sapiens (human)
bile acid metabolic processAldo-keto reductase family 1 member C1Homo sapiens (human)
bile acid and bile salt transportAldo-keto reductase family 1 member C1Homo sapiens (human)
intestinal cholesterol absorptionAldo-keto reductase family 1 member C1Homo sapiens (human)
epithelial cell differentiationAldo-keto reductase family 1 member C1Homo sapiens (human)
progesterone metabolic processAldo-keto reductase family 1 member C1Homo sapiens (human)
retinal metabolic processAldo-keto reductase family 1 member C1Homo sapiens (human)
cholesterol homeostasisAldo-keto reductase family 1 member C1Homo sapiens (human)
daunorubicin metabolic processAldo-keto reductase family 1 member C1Homo sapiens (human)
doxorubicin metabolic processAldo-keto reductase family 1 member C1Homo sapiens (human)
response to organophosphorusAldo-keto reductase family 1 member C1Homo sapiens (human)
cellular response to jasmonic acid stimulusAldo-keto reductase family 1 member C1Homo sapiens (human)
positive regulation of reactive oxygen species metabolic processAldo-keto reductase family 1 member C1Homo sapiens (human)
prostaglandin metabolic processAldo-keto reductase family 1 member C1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (21)

Processvia Protein(s)Taxonomy
aldose reductase (NADPH) activityAldo-keto reductase family 1 member C1Homo sapiens (human)
aldo-keto reductase (NADPH) activityAldo-keto reductase family 1 member C1Homo sapiens (human)
estradiol 17-beta-dehydrogenase [NAD(P)] activityAldo-keto reductase family 1 member C1Homo sapiens (human)
protein bindingAldo-keto reductase family 1 member C1Homo sapiens (human)
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptorAldo-keto reductase family 1 member C1Homo sapiens (human)
phenanthrene 9,10-monooxygenase activityAldo-keto reductase family 1 member C1Homo sapiens (human)
testosterone dehydrogenase [NAD(P)] activityAldo-keto reductase family 1 member C1Homo sapiens (human)
carboxylic acid bindingAldo-keto reductase family 1 member C1Homo sapiens (human)
bile acid bindingAldo-keto reductase family 1 member C1Homo sapiens (human)
3beta-hydroxy-5beta-steroid dehydrogenase activityAldo-keto reductase family 1 member C1Homo sapiens (human)
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorAldo-keto reductase family 1 member C1Homo sapiens (human)
dihydrotestosterone 17-beta-dehydrogenase activityAldo-keto reductase family 1 member C1Homo sapiens (human)
17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activityAldo-keto reductase family 1 member C1Homo sapiens (human)
5alpha-androstane-3beta,17beta-diol dehydrogenase activityAldo-keto reductase family 1 member C1Homo sapiens (human)
androsterone dehydrogenase (B-specific) activityAldo-keto reductase family 1 member C1Homo sapiens (human)
androstan-3-alpha,17-beta-diol dehydrogenase activityAldo-keto reductase family 1 member C1Homo sapiens (human)
testosterone 17-beta-dehydrogenase (NADP+) activityAldo-keto reductase family 1 member C1Homo sapiens (human)
ketosteroid monooxygenase activityAldo-keto reductase family 1 member C1Homo sapiens (human)
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activityAldo-keto reductase family 1 member C1Homo sapiens (human)
indanol dehydrogenase activityAldo-keto reductase family 1 member C1Homo sapiens (human)
androsterone dehydrogenase activityAldo-keto reductase family 1 member C1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (2)

Processvia Protein(s)Taxonomy
cytosolAldo-keto reductase family 1 member C1Homo sapiens (human)
extracellular exosomeAldo-keto reductase family 1 member C1Homo sapiens (human)
cytosolAldo-keto reductase family 1 member C1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (5)

Assay IDTitleYearJournalArticle
AID1224817Assays to identify small molecules inhibitory for eIF4E expression2015Chemistry & biology, Jul-23, Volume: 22, Issue:7
Internal Ribosome Entry Site-Based Bicistronic In Situ Reporter Assays for Discovery of Transcription-Targeted Lead Compounds.
AID735518Inhibition of recombinant AKR1C3 (unknown origin) assessed as decrease in oxidation of 1-acenaphthenol substrate at 100 uM by spectrophotometric analysis2013European journal of medicinal chemistry, Apr, Volume: 622,3-Diarylpropenoic acids as selective non-steroidal inhibitors of type-5 17β-hydroxysteroid dehydrogenase (AKR1C3).
AID735522Inhibition of human recombinant AKR1C1 expressed in Escherichia coli assessed as decrease in oxidation of 1-acenaphthenol substrate at 100 uM by spectrophotometric analysis2013European journal of medicinal chemistry, Apr, Volume: 622,3-Diarylpropenoic acids as selective non-steroidal inhibitors of type-5 17β-hydroxysteroid dehydrogenase (AKR1C3).
AID735520Inhibition of recombinant AKR1C2 (unknown origin) assessed as decrease in oxidation of 1-acenaphthenol substrate at 100 uM by spectrophotometric analysis2013European journal of medicinal chemistry, Apr, Volume: 622,3-Diarylpropenoic acids as selective non-steroidal inhibitors of type-5 17β-hydroxysteroid dehydrogenase (AKR1C3).
AID735521Inhibition of human recombinant AKR1C1 expressed in Escherichia coli assessed as decrease in oxidation of 1-acenaphthenol substrate by spectrophotometric analysis2013European journal of medicinal chemistry, Apr, Volume: 622,3-Diarylpropenoic acids as selective non-steroidal inhibitors of type-5 17β-hydroxysteroid dehydrogenase (AKR1C3).
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (14.29)18.7374
1990's3 (42.86)18.2507
2000's0 (0.00)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
medroxyprogesterone acetate[no description available]medium1020-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
corticosteroid;
steroid ester		adjuvant;
androgen;
antineoplastic agent;
antioxidant;
female contraceptive drug;
inhibitor;
progestin;
synthetic oral contraceptive
2-(3-pyridine)acetic acid[no description available]medium10monocarboxylic acid;
pyridines		human xenobiotic metabolite
ureidosuccinic acid[no description available]medium10aspartic acid derivative;
C4-dicarboxylic acid;
N-carbamoyl-amino acid		Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite
arabinofuranosylcytosine triphosphate[no description available]medium10pyrimidine ribonucleoside monophosphate
aminoethylphosphonic acid[no description available]medium10phosphonic acids;
primary amino compound;
zwitterion		human metabolite;
metabolite;
mouse metabolite
gamma-guanidinobutyric acid[no description available]medium10guanidines;
monocarboxylic acid;
zwitterion		fungal metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
inositol[no description available]medium10cyclitol;
hexol
pentachlorophenol[no description available]medium10aromatic fungicide;
chlorophenol;
organochlorine pesticide;
pentachlorobenzenes		human xenobiotic metabolite
phenylalanine[no description available]medium10alpha-amino acid;
aromatic amino acid		Daphnia magna metabolite
nsc-267703[no description available]medium10anthracycline
n-acetyltryptophan[no description available]medium10N-acetyl-amino acid;
tryptophan derivative		metabolite
tyrphostin ag957[no description available]medium10aromatic amine
2-amino-4-phosphonobutyric acid[no description available]medium10
aristolochic acid i[no description available]medium10aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin
benzbromarone[no description available]medium101-benzofurans;
aromatic ketone		uricosuric drug
benzylhydrochlorothiazide[no description available]medium10benzenes;
benzothiadiazine;
organochlorine compound;
secondary amino compound;
sulfonamide
eucalyptol[no description available]medium10
amberlite cg 400[no description available]medium10methyl ester;
organic heteropentacyclic compound;
yohimban alkaloid
stallimycin[no description available]medium10
domperidone[no description available]medium10benzimidazoles;
heteroarylpiperidine		antiemetic;
dopaminergic antagonist
ellipticine[no description available]medium10indole alkaloid;
organic heterotetracyclic compound;
organonitrogen heterocyclic compound;
polycyclic heteroarene		antineoplastic agent;
plant metabolite
glyphosate[no description available]medium10glycine derivative;
phosphonic acid		agrochemical;
EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor;
herbicide
haloperidol[no description available]medium10aromatic ketone;
hydroxypiperidine;
monochlorobenzenes;
organofluorine compound;
tertiary alcohol		antidyskinesia agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist
miltefosine[no description available]medium10phosphocholines;
phospholipid		anti-inflammatory agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antiprotozoal drug;
apoptosis inducer;
immunomodulator;
protein kinase inhibitor
hypericin[no description available]medium10
batyl alcohol[no description available]medium10alkylglycerol
imipramine[no description available]medium10dibenzoazepineadrenergic uptake inhibitor;
antidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
nsc 664704[no description available]medium10indolobenzazepine;
lactam;
organobromine compound		cardioprotective agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
geroprotector
ketoconazole[no description available]medium10dichlorobenzene;
dioxolane;
ether;
imidazoles;
N-acylpiperazine;
N-arylpiperazine
khellin[no description available]medium10furanochromone;
organic heterotricyclic compound;
oxacycle		anti-asthmatic agent;
bronchodilator agent;
cardiovascular drug;
vasodilator agent
2-amino-3-phosphonopropionic acid[no description available]medium10alanine derivative;
non-proteinogenic alpha-amino acid;
phosphonic acids		human metabolite;
metabotropic glutamate receptor antagonist
benzylsuccinic acid[no description available]medium10dicarboxylic acidbacterial xenobiotic metabolite
beta-lapachone[no description available]medium10benzochromenone;
orthoquinones		anti-inflammatory agent;
antineoplastic agent;
plant metabolite
mesoridazine[no description available]medium10phenothiazines;
sulfoxide;
tertiary amino compound		dopaminergic antagonist;
first generation antipsychotic
methoxsalen[no description available]medium10aromatic ether;
psoralens		antineoplastic agent;
cross-linking reagent;
dermatologic drug;
photosensitizing agent;
plant metabolite
oxaprozin[no description available]medium101,3-oxazoles;
monocarboxylic acid		analgesic;
non-steroidal anti-inflammatory drug
penicillamine[no description available]medium10non-proteinogenic alpha-amino acid;
thiol
pentoxifylline[no description available]medium10oxopurine
phenolsulfonphthalein[no description available]medium102,1-benzoxathiole;
arenesulfonate ester;
phenols;
sultone		acid-base indicator;
diagnostic agent;
two-colour indicator
Picrotin, analytical standard[no description available]medium10furopyran
pomiferin[no description available]medium10isoflavanones
pridinol[no description available]medium10piperidines;
tertiary alcohol		antiparkinson drug;
muscle relaxant
sulfaquinoxaline[no description available]medium10benzenes;
sulfonamide
suramin[no description available]medium10naphthalenesulfonic acid;
phenylureas;
secondary carboxamide		angiogenesis inhibitor;
antinematodal drug;
antineoplastic agent;
apoptosis inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
GABA antagonist;
GABA-gated chloride channel antagonist;
purinergic receptor P2 antagonist;
ryanodine receptor agonist;
trypanocidal drug
4-methylglutamic acid[no description available]medium10amino dicarboxylic acid;
glutamic acid derivative
pilocarpine hydrochloride[no description available]medium10hydrochloride
veratramine[no description available]medium10piperidine alkaloid
gibberellic acid[no description available]medium10C19-gibberellin;
gibberellin monocarboxylic acid;
lactone;
organic heteropentacyclic compound		mouse metabolite;
plant metabolite
santowhite powder[no description available]medium10
fentichlor[no description available]medium10aryl sulfide;
bridged diphenyl antifungal drug;
monochlorobenzenes;
polyphenol		antiinfective agent;
drug allergen
pyrrolidonecarboxylic acid[no description available]medium105-oxoproline;
L-proline derivative;
non-proteinogenic L-alpha-amino acid		algal metabolite
hexadecanolide[no description available]medium10macrolide
pamoic acid[no description available]medium10dicarboxylic acid
carzenide[no description available]medium10sulfonamide
estradiol 17 beta-cypionate[no description available]medium10steroid ester
lithocholic acid[no description available]medium10bile acid;
C24-steroid;
monohydroxy-5beta-cholanic acid		geroprotector;
human metabolite;
mouse metabolite
jervine[no description available]medium10piperidines
bicuculline[no description available]medium10benzylisoquinoline alkaloid;
isoquinoline alkaloid;
isoquinolines		agrochemical;
central nervous system stimulant;
GABA-gated chloride channel antagonist;
GABAA receptor antagonist;
neurotoxin
salicylurate[no description available]medium10N-acylglycine;
secondary carboxamide		human xenobiotic metabolite;
uremic toxin
3,5-pyridinedicarboxylic acid[no description available]medium10pyridinedicarboxylic acid
ricinine[no description available]medium10nitrile;
pyridine alkaloid;
pyridone
carinamide[no description available]medium10
3,5-dibromotyrosine[no description available]medium10monocarboxylic acid
hematoporphyrin[no description available]medium10
1H-indazol-3-amine[no description available]medium10indazoles
1,1'-methylenedi-2-naphthol[no description available]medium10
tricarballylic acid[no description available]medium10tricarboxylic acid
popop[no description available]medium101,3-oxazolesfluorochrome
2-tert-butylhydroquinone[no description available]medium10hydroquinonesfood antioxidant
7-hydroxychlorpromazine[no description available]medium10phenothiazines
cme-carbodiimide[no description available]medium10
cyclacillin[no description available]medium10penicillinantibacterial drug
strombine[no description available]medium10
thymolphthalein[no description available]medium10terpene lactone
1,4,5,8-naphthalenetetracarboxylic acid[no description available]medium10
(7S,9S)-7-[(4-amino-5-hydroxy-6-methyl-2-oxanyl)oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione[no description available]medium10anthracycline
hydroxyphenylazouracil[no description available]medium10
canadine[no description available]medium10aromatic ether;
berberine alkaloid;
organic heteropentacyclic compound;
oxacycle
pimonidazole[no description available]medium10
flavone acetic acid[no description available]medium10
trichlorophene[no description available]medium10
verapamil hydrochloride[no description available]medium10
4-aminomethylbenzoic acid[no description available]medium10benzoic acids
cedrol[no description available]medium10cedrane sesquiterpenoid;
tertiary alcohol
propazole[no description available]medium10benzimidazoles
reserpic acid[no description available]medium10yohimban alkaloid
pifexole[no description available]medium10
Diphenolic acid[no description available]medium10bisphenol
Melicopidine[no description available]medium10acridines
resorufin[no description available]medium10phenoxazine
vinburnine[no description available]medium10alkaloid
pacein[no description available]medium10
alantolactone[no description available]medium10naphthofuran;
olefinic compound;
sesquiterpene lactone		antineoplastic agent;
apoptosis inducer;
plant metabolite
2-(4'-methylpiperazino-1-methyl)-1,3-diazafluoranthene 1-oxide[no description available]medium10
tetrandrine[no description available]medium10bisbenzylisoquinoline alkaloid;
isoquinolines
stictic acid[no description available]medium10aromatic ether
gallocyanine[no description available]medium10
propylsulfonic acid[no description available]medium10
1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide[no description available]medium10carbodiimide;
morpholines		cross-linking reagent
6,6'-dithiodinicotinic acid[no description available]medium10
va 061[no description available]medium10
n-acetyltyrosine, (dl)-isomer[no description available]medium10N-acetyl-amino acid;
phenols;
tyrosine derivative		human urinary metabolite
cinchonine[no description available]medium10(8xi)-cinchonan-9-ol;
cinchona alkaloid		metabolite
n(6)-(delta(2)-isopentenyl)adenine[no description available]medium106-isopentenylaminopurinecytokinin
2-Phthalimidoglutaricacid[no description available]medium10glutamic acid derivative
nsc-87877[no description available]medium10
methyl lithocholate[no description available]medium10
nipecotic acid amide[no description available]medium10piperidinecarboxamide
dimethacrine[no description available]medium10acridines
dehydroabietic acid[no description available]medium10abietane diterpenoid;
carbotricyclic compound;
monocarboxylic acid		allergen;
metabolite
4-deoxypyridoxine 5'-phosphate[no description available]medium10
4-(phenylthio)butanoic acid[no description available]medium10
bis-a-tda[no description available]medium10
1-amino-2-phenylethylphosphonic acid[no description available]medium10
4-fluoro-alpha-hydroxybenzeneacetic acid[no description available]medium10
Isopteropodin[no description available]medium10indolizines
benzpiperylone[no description available]medium10pyrazoles;
ring assembly
carboxyamido-triazole[no description available]medium10
nsc 607097[no description available]medium10
pacifenol[no description available]medium10
n-phenyliminodiacetic acid[no description available]medium10
cyc 202[no description available]medium102,6-diaminopurinesantiviral drug;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
cystamine hydrochloride[no description available]medium10
dipiperidinoethane-di-n-oxide[no description available]medium10
benzyl-beta-d-xyloside[no description available]medium10
2,2'-(3-methylcyclohexane-1,1-diyl)diacetic acid[no description available]medium10dicarboxylic acid
2,4-dinitrophenylacetic acid[no description available]medium10
sitosterol, (3beta)-isomer[no description available]medium103beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
C29-steroid;
phytosterols;
stigmastane sterol		anticholesteremic drug;
antioxidant;
mouse metabolite;
plant metabolite;
sterol methyltransferase inhibitor
(5-Phenyl-1,2,4-triazol-3-yl)urea[no description available]medium10benzenes
fumagillol[no description available]medium10secondary alcohol;
sesquiterpenoid;
spiro-epoxide		antimicrobial agent
vacquinol-1[no description available]medium10
aspidospermine[no description available]medium10indole alkaloid
guaiol[no description available]medium10guaiane sesquiterpenoid
benzatropine methanesulfonate[no description available]medium10
pseudoyohimbine[no description available]medium10methyl 17-hydroxy-20xi-yohimban-16-carboxylate
gant58[no description available]medium10pyridines
nsc 88915[no description available]medium10
o-acetylsolasodine[no description available]medium10
viroallosecurinine[no description available]medium10indolizines
4-methyl-2-quinazolinamine[no description available]medium10
1-amino-9,10-dioxo-4-(3-sulfamoylanilino)anthracene-2-sulfonic acid[no description available]medium10
adamantoylcytarabine[no description available]medium10
6,11-dioxo-12-naphtho[2,3-b]indolizinecarboxylic acid ethyl ester[no description available]medium10naphthalenes
noscapine[no description available]medium10aromatic ether;
benzylisoquinoline alkaloid;
cyclic acetal;
isobenzofuranone;
organic heterobicyclic compound;
organic heterotricyclic compound;
tertiary amino compound		antineoplastic agent;
antitussive;
apoptosis inducer;
plant metabolite
LSM-1290[no description available]medium10benzazepine alkaloid;
cyclic acetal
2-glycineamide-5-chlorophenyl-2-pyrryl ketone[no description available]medium10
nsc 154020[no description available]medium10N-glycosyl compound
4-[(1-naphthalenylamino)-oxomethyl]benzene-1,3-dicarboxylic acid[no description available]medium102-hydroxyisophthalic acid
2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one[no description available]medium10cyclic ketone;
quinuclidines
5-(1,3-benzodioxol-5-yl)-N-(2,4-dimethylphenyl)-1,3,4-oxadiazol-2-amine[no description available]medium10benzodioxoles
croton factor f1[no description available]medium10phorbol ester;
tertiary alpha-hydroxy ketone
medicarpin[no description available]medium10medicarpinplant metabolite
gitoxigenin[no description available]medium1014beta-hydroxy steroid;
16beta-hydroxy steroid;
3beta-hydroxy steroid
aromoline[no description available]medium10
nsc668394[no description available]medium10
gant 61[no description available]medium10aminal;
dialkylarylamine;
pyridines;
substituted aniline;
tertiary amino compound		antineoplastic agent;
apoptosis inducer;
glioma-associated oncogene inhibitor;
Hedgehog signaling pathway inhibitor
nortriptyline hydrochloride[no description available]medium10organic tricyclic compoundgeroprotector
nsc 45641[no description available]medium10
geraniol[no description available]medium103,7-dimethylocta-2,6-dien-1-ol;
monoterpenoid;
primary alcohol		allergen;
fragrance;
plant metabolite;
volatile oil component
aconitic acid[no description available]medium10aconitic acidfundamental metabolite
amygdalin[no description available]medium10
curcumin[no description available]medium10aromatic ether;
beta-diketone;
diarylheptanoid;
enone;
polyphenol		anti-inflammatory agent;
antifungal agent;
antineoplastic agent;
biological pigment;
contraceptive drug;
dye;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
EC 1.8.1.9 (thioredoxin reductase) inhibitor;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
flavouring agent;
food colouring;
geroprotector;
hepatoprotective agent;
immunomodulator;
iron chelator;
ligand;
lipoxygenase inhibitor;
metabolite;
neuroprotective agent;
nutraceutical;
radical scavenger
ethyldimethylaminopropyl carbodiimide[no description available]medium10
tamoxifen citrate[no description available]medium10citrate saltangiogenesis inhibitor;
anticoronaviral agent
eskazine[no description available]medium10
nsc 336628[no description available]medium10
1,3-dimethyl-8-[2-(1-pyrrolidinyl)ethylthio]-6-sulfanylidene-7H-purin-2-one[no description available]medium10oxopurine
cambinol[no description available]medium10
nsc 117199[no description available]medium10
mangostin[no description available]medium10aromatic ether;
phenols;
xanthones		antimicrobial agent;
antineoplastic agent;
antioxidant;
plant metabolite
coumestrol[no description available]medium10coumestans;
delta-lactone;
polyphenol		anti-inflammatory agent;
antioxidant;
plant metabolite
rottlerin[no description available]medium10aromatic ketone;
benzenetriol;
chromenol;
enone;
methyl ketone		anti-allergic agent;
antihypertensive agent;
antineoplastic agent;
apoptosis inducer;
K-ATP channel agonist;
metabolite
ellagic acid[no description available]medium10catechols;
cyclic ketone;
lactone;
organic heterotetracyclic compound;
polyphenol		antioxidant;
EC 1.14.18.1 (tyrosinase) inhibitor;
EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor;
EC 2.4.1.1 (glycogen phosphorylase) inhibitor;
EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor;
EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor;
EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
food additive;
fungal metabolite;
geroprotector;
plant metabolite;
skin lightening agent
7,8-dimethylalloxazine[no description available]medium107,8-dimethylbenzo[g]pteridine-2,4-dioneplant metabolite
dihydrothobainone[no description available]medium10
piperic acid[no description available]medium10alpha,beta-unsaturated monocarboxylic acid;
benzodioxoles		plant metabolite
abscisic acid[no description available]medium10abscisic acids
radicinin[no description available]medium10aromatic ketone
5,6-dichloro-1H-imidazo[4,5-b]pyrazine-2-carboxylic acid[no description available]medium10imidazopyrazine
hispanolone[no description available]medium10
veratridine[no description available]medium10
zimelidine hydrochloride[no description available]medium10
chlortetracycline hydrochloride[no description available]medium10
viridicatumtoxin[no description available]medium10
dacarbazine[no description available]medium10dacarbazine
hematein[no description available]medium10
cobalt[no description available]medium10cobalt group element atom;
metal allergen		micronutrient
valinomycin[no description available]medium10cyclodepsipeptide;
macrocycle		antimicrobial agent;
antiviral agent;
bacterial metabolite;
potassium ionophore
tamoxifen[no description available]medium10stilbenoid;
tertiary amino compound		angiogenesis inhibitor;
antineoplastic agent;
bone density conservation agent;
EC 1.2.3.1 (aldehyde oxidase) inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
estrogen antagonist;
estrogen receptor antagonist;
estrogen receptor modulator
4,4'-diisothiocyanostilbene-2,2'-disulfonic acid[no description available]medium10
4-acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid[no description available]medium20stilbenoid
chlorine[no description available]medium30halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
oxalates[no description available]medium10
fluorescein[no description available]medium102-benzofurans;
gamma-lactone;
organic heteropentacyclic compound;
oxaspiro compound;
polyphenol;
xanthene dye		fluorescent dye;
radioopaque medium
erythrosine[no description available]medium10
fenamic acid[no description available]medium10aminobenzoic acid;
secondary amino compound		membrane transport modulator
theophylline[no description available]medium10dimethylxanthineadenosine receptor antagonist;
anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
drug metabolite;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
fungal metabolite;
human blood serum metabolite;
immunomodulator;
muscle relaxant;
vasodilator agent
loperamide[no description available]medium10monocarboxylic acid amide;
monochlorobenzenes;
piperidines;
tertiary alcohol		anticoronaviral agent;
antidiarrhoeal drug;
mu-opioid receptor agonist
ConditionIndicatedRelationship StrengthStudiesTrials