glyphosate has been researched along with Alzheimer Disease in 1 studies
glyphosate: active cpd in herbicidal formulation Roundup; inhibits EC 2.5.1.19, 5-enolpyruvylshikimate-3-phosphate synthase; structure
glyphosate : A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glyphosate has been shown to cross the blood-brain barrier in in vitro models, but has yet to be verified in vivo." | 1.72 | Glyphosate infiltrates the brain and increases pro-inflammatory cytokine TNFα: implications for neurodegenerative disorders. ( Huentelman, MJ; Pathak, KV; Piras, IS; Pirrotte, P; Sharma, R; Velazquez, R; White, J; Winslow, W; Winstone, JK, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Winstone, JK | 1 |
| Pathak, KV | 1 |
| Winslow, W | 1 |
| Piras, IS | 1 |
| White, J | 1 |
| Sharma, R | 1 |
| Huentelman, MJ | 1 |
| Pirrotte, P | 1 |
| Velazquez, R | 1 |
1 other study available for glyphosate and Alzheimer Disease
| Article | Year |
|---|---|
Glyphosate infiltrates the brain and increases pro-inflammatory cytokine TNFα: implications for neurodegenerative disorders.
Topics: Alzheimer Disease; Animals; Brain; Chromatography, Liquid; Cytokines; Glycine; Glyphosate; Herbicide | 2022 |