Fatigue, Mental

A condition of low alertness or cognitive impairment, usually associated with prolonged mental activities or stress.

Synonym
Mental Fatigue
Fatigue, Mental

Excerpt	Reference
"A framework for mental fatigue is proposed, that involves an integrated evaluation of both expected rewards and energetical costs associated with continued performance."	( Boksem, MA; Tops, M, 2008)
"Mental fatigue is known to influence muscle function and motor performance, but its contribution to the development of voluntary physical fatigue is not well understood."	( Mehta, RK; Parasuraman, R, 2014)
"Mental fatigue is often characterized by reduced motivation for effortful activity and impaired task performance."	( Bakker, AB; Hopstaken, JF; Kompier, MA; van der Linden, D, 2015)
"Although mental fatigue is a complex, multi-facetted state that involves changes in motivation, cognition, and mood, one of its main characteristics is reduced task engagement."	( Bakker, AB; Hopstaken, JF; Kompier, MA; van der Linden, D, 2015)
"Stress and mental fatigue are major health threats to employees in office-based occupations."	( Andersson, K; Calogiuri, G; Evensen, K; Ihlebæk, C; Patil, G; Raanaas, RK; Weydahl, A, 2015)
"Mental fatigue is a psychobiological state caused by prolonged periods of demanding cognitive activity and has been observed to decrease time trial (TT) endurance performance by ∼3."	( Buyse, L; DE Pauw, K; Marcora, S; Meeusen, R; Roelands, B; VAN Cutsem, J, 2017)
"Mental fatigue is a psychobiological state caused by prolonged periods of demanding cognitive activity that has negative implications on many aspects in daily life."	( De Pauw, K; Marcora, S; Meeusen, R; Roelands, B; Van Cutsem, J, 2018)

Excerpt	Reference
"2) Mental fatigue affects several neurotransmitter systems, with presumably an important role for dopamine and adenosine, in multiple brain regions such as the prefrontal cortex and the anterior cingulate cortex."	( Meeusen, R; Roelands, B; Van Cutsem, J, 2021)

Excerpt	Reference
"5) Sleep and mental fatigue were related to the aggravation of QOL at 5-6 days after Carboplatin treatment."	( Hojou, N; Hoshi, A; Ishihara, Y; Kobayashi, K; Kuratomi, Y; Matsuoka, R; Nishiwaki, Y; Nukariya, N; Sakai, H; Yoneda, S, 1995)
"Methylphenidate decreased mental fatigue for subjects suffering a traumatic brain injury, the treatment is considered to be safe and is recommended, starting with a low dose."	( Andréll, P; Johansson, B; Mannheimer, C; Odenstedt, J; Rönnbäck, L; Wentzel, AP, 2014)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	73 (32.88)	23.3326
1990's	17 (7.66)	12.5806
2000's	30 (13.51)	18.1394
2010's	71 (31.98)	28.8240
2020's	31 (13.96)	9.53

Drug	Relationship Strength	Studies	Trials
acetylcarnitine	medium	2	1
ammonium hydroxide	medium	2	1
beta-alanine	medium	1	1
carbamates	low	2	0
carnitine	medium	3	2
chlorine	low	1	0
bupropion	medium	2	1
creatine	medium	1	1
lactic acid	medium	6	3
histamine	low	1	0
dihydroxyphenylalanine	low	2	0
kynurenine	low	1	0
methanol	low	1	0
melatonin	medium	1	1
nitrates	low	2	0
nitrites	low	1	0
oxaloacetic acid	medium	1	1
uric acid	low	1	0
mandelic acid	low	1	0
4-aminopyridine	medium	2	1
amantadine	low	1	0
theophylline	low	1	0
caffeine	medium	19	10
chloral hydrate	medium	1	1
chlorpromazine	medium	3	1
amphetamine	low	2	0
furazolidone	medium	1	1
glyphosate	low	1	0
ketamine	medium	1	1
meclofenoxate	low	1	0
methyl parathion	medium	1	1
methylphenidate	medium	9	6
modafinil	low	1	0
pamidronate	medium	1	1
pemoline	low	1	0
pentobarbital	medium	2	1
phenobarbital	low	1	0
piracetam	medium	1	1
procaine	low	1	0
prochlorperazine	low	1	0
promethazine	low	1	0
thioridazine	low	1	0
trimipramine	medium	1	1
tyramine	medium	1	1
reserpine	low	1	0
thyroxine	low	1	0
dextroamphetamine	medium	1	1
dehydroepiandrosterone	medium	2	2
metaraminol	low	1	0
amifampridine	low	1	0
triiodothyronine	low	1	0
alanine	medium	1	1
serine	medium	2	2
aspartic acid	medium	5	1
tubocurarine	low	1	0
galactose	medium	1	1
carbostyril	low	1	0
phenylethyl alcohol	low	1	0
tyrosine	medium	2	2
methylene blue	low	1	0
methionine	low	1	0
phenylalanine	medium	1	1
tryptophan	medium	5	2
pyrazines	low	1	0
ephedrine	low	1	0
testosterone enanthate	medium	1	1
citrulline	low	3	0
4-hydroxyphenylethanol	low	1	0
malondialdehyde	medium	1	1
hematoporphyrin	low	1	0
3-hydroxyflavone	medium	1	1
erythromycin	low	1	0
s,n,n'-tripropylthiocarbamate	low	17	0
pimozide	low	1	0
sabinene	low	1	0
trolamine salicylate	low	2	0
phenyl acetate	low	1	0
cetylpyridinium chloride anhydrous	medium	5	2
4-methoxyamphetamine	low	1	0
transferrin	low	1	0
glutamic acid	medium	2	1
fomesafen	medium	10	2
glucose, (beta-d)-isomer	low	1	0
testosterone undecanoate	medium	1	1
acemannan	medium	1	1
sesamin	medium	1	1
nsc-172755	low	1	0
fibrinogen	medium	1	1
3-(2,2,2-trimethylhydrazine)propionate	low	1	0
acth (4-9)	low	1	0
cucurbitaceae	medium	1	1
rhodioloside	low	1	0
clorazepate dipotassium	medium	1	1
atropine	low	1	0
carboplatin	low	1	0
glycogen	low	1	0
glucosamine	medium	1	1
theanine	medium	1	1
taxifolin	medium	1	1
lignans	medium	2	2
retinol	low	1	0
chlorogenic acid	low	1	0
D-fructopyranose	medium	2	1
tamoxifen	low	1	0
thiopental	medium	1	1
lithium	low	2	0
galactomannan	medium	1	1
quercetin	low	1	0
vitamin k semiquinone radical	low	1	0
rosin	low	1	0
alpha-linolenic acid	medium	1	1
astaxanthine	medium	1	1
phosphorus	low	1	0
radium	medium	2	1
phosphocreatine	medium	2	1
osu 6162	medium	2	2
oxadiazoles	medium	1	1
pituitrin	low	1	0
c-peptide	low	1	0
phosphatidylcholines	medium	1	1
vx-770	low	1	0
vendex	low	1	0
arabinogalactan	medium	1	1
egg white	medium	1	1
cardiovascular agents	low	1	0
mannans	medium	1	1
piperidines	medium	2	2
cobamamide	medium	1	1
vitamin b 12	low	1	0
exudates	low	2	0
deoxyguanosine	low	1	0
8-hydroxy-2'-deoxyguanosine	low	1	0
maltodextrin	low	1	0
ego	medium	3	2
leptin	low	1	0

Protein Targets (1,197)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Gamma-butyrobetaine dioxygenase	0	2	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	18	0	0	18
Chain A, 2-oxoglutarate Oxygenase	16	0	0	16
glp-1 receptor, partial	9	0	0	9
USP1 protein, partial	22	0	0	22
TDP1 protein	27	0	0	27
Smad3	6	0	0	6
apical membrane antigen 1, AMA1	9	0	0	9
cellular tumor antigen p53 isoform a	8	0	0	8
importin subunit beta-1 isoform 1	6	0	0	6
mitogen-activated protein kinase 1	15	0	0	15
snurportin-1	6	0	0	6
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
DNA polymerase eta isoform 1	7	0	0	7
DNA polymerase iota isoform a (long)	15	0	0	15
urokinase-type plasminogen activator precursor	8	0	0	8
plasminogen precursor	8	0	0	8
urokinase plasminogen activator surface receptor precursor	8	0	0	8
nuclear receptor ROR-gamma isoform 1	10	0	0	10
geminin	33	0	0	33
cytochrome P450 3A4 isoform 1	16	0	0	16
lamin isoform A-delta10	25	0	0	25
Gamma-aminobutyric acid receptor subunit pi	16	2	1	19
Polyunsaturated fatty acid lipoxygenase ALOX15B	7	2	0	9
Carbonic anhydrase 12	0	4	0	9
Carbonic anhydrase 1	0	10	0	19
Carbonic anhydrase 2	0	10	0	20
Integrin beta-3	8	0	1	9
ATP-dependent translocase ABCB1	0	9	3	13
Integrin alpha-IIb	8	0	1	9
Calmodulin-1	0	5	1	6
Androgen receptor	0	2	0	2
Pyruvate kinase PKM	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-1	16	2	1	19
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX12	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	16	2	1	19
Gamma-aminobutyric acid receptor subunit gamma-2	16	2	1	19
Gamma-aminobutyric acid receptor subunit alpha-5	16	2	1	19
Gamma-aminobutyric acid receptor subunit alpha-3	16	2	1	19
Gamma-aminobutyric acid receptor subunit gamma-1	16	2	1	19
Gamma-aminobutyric acid receptor subunit alpha-2	16	2	1	19
Gamma-aminobutyric acid receptor subunit alpha-4	16	2	1	19
Gamma-aminobutyric acid receptor subunit gamma-3	16	2	1	19
Gamma-aminobutyric acid receptor subunit alpha-6	16	2	1	19
Histamine H2 receptor	7	0	1	9
Xanthine dehydrogenase/oxidase	0	3	0	3
Fatty acid synthase	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	16	2	1	19
Gamma-aminobutyric acid receptor subunit beta-3	16	2	1	19
Gamma-aminobutyric acid receptor subunit beta-2	16	2	1	19
Cytochrome P450 1B1	0	6	1	7
Carbonic anhydrase 9	0	3	0	8
GABA theta subunit	16	2	1	19
Aurora kinase B	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	16	2	1	19
Dipeptidyl peptidase 3	0	2	0	2
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Chain A, Cruzipain	4	0	0	4
thioredoxin reductase	22	0	0	22
RAR-related orphan receptor gamma	29	0	0	29
Microtubule-associated protein tau	17	0	0	17
aldehyde dehydrogenase 1 family, member A1	15	0	0	15
thyroid stimulating hormone receptor	13	0	0	13
estrogen receptor 2 (ER beta)	21	0	0	21
cytochrome P450 family 3 subfamily A polypeptide 4	22	0	0	22
glucocorticoid receptor [Homo sapiens]	31	0	0	31
cytochrome P450 2D6	16	0	0	16
glucocerebrosidase	6	0	0	6
IDH1	12	0	0	12
euchromatic histone-lysine N-methyltransferase 2	33	0	0	33
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	15	0	0	15
cytochrome P450 2D6 isoform 1	8	0	0	8
chromobox protein homolog 1	23	0	0	23
transcriptional regulator ERG isoform 3	4	0	0	4
thyroid hormone receptor beta isoform 2	25	0	0	25
peripheral myelin protein 22	16	0	0	16
survival motor neuron protein isoform d	8	0	0	8
lethal factor (plasmid)	15	0	0	15
Potassium channel subfamily K member 2	0	2	4	6
Rap guanine nucleotide exchange factor 3	7	0	0	7
Cellular tumor antigen p53	21	0	0	21
Potassium voltage-gated channel subfamily A member 3	0	0	1	1
Acetylcholinesterase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	14	0	14
ATP-dependent phosphofructokinase	18	0	0	18
GLS protein	20	0	0	20
Hepatocyte growth factor receptor	0	2	0	2
Replicase polyprotein 1ab	0	10	4	14
Carbonic anhydrase 5A, mitochondrial	0	2	0	8
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase	0	1	0	7
Carbonic anhydrase	0	1	0	7
Carbonic anhydrase 5B, mitochondrial	0	2	0	8
5-hydroxytryptamine receptor 2C	0	4	4	8
5-hydroxytryptamine receptor 2A	0	4	4	8
5-hydroxytryptamine receptor 1A	0	13	4	17
5-hydroxytryptamine receptor 1B	0	12	4	16
5-hydroxytryptamine receptor 1D	0	2	4	6
5-hydroxytryptamine receptor 1F	0	2	4	6
5-hydroxytryptamine receptor 2B	0	4	4	8
5-hydroxytryptamine receptor 6	0	0	4	4
Sodium-dependent serotonin transporter	0	19	2	21
Sodium-dependent serotonin transporter	0	4	1	5
5-hydroxytryptamine receptor 7	0	2	4	6
5-hydroxytryptamine receptor 5A	0	0	4	4
5-hydroxytryptamine receptor 5B	0	0	4	4
5-hydroxytryptamine receptor 3A	0	0	4	4
5-hydroxytryptamine receptor 4	0	0	4	4
5-hydroxytryptamine receptor 3B	0	0	4	4
Chain A, Avidin	0	0	2	2
Chain A, Avidin	0	0	2	2
Chain B, Avidin	0	0	2	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	16	0	0	16
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	3
Glutamate receptor ionotropic, NMDA 1	1	9	1	16
Proton-coupled amino acid transporter 1	0	4	0	4
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	0	0	3
Chain A, Beta-lactamase	13	0	0	13
Chain A, HADH2 protein	10	0	0	10
Chain B, HADH2 protein	10	0	0	10
Chain A, ATP-DEPENDENT DNA HELICASE Q1	7	0	0	7
Luciferase	8	0	0	8
15-lipoxygenase, partial	9	0	0	9
WRN	2	0	0	2
phosphopantetheinyl transferase	22	0	0	22
hypoxia-inducible factor 1 alpha subunit	10	0	0	10
SMAD family member 2	10	0	0	10
SMAD family member 3	10	0	0	10
GLI family zinc finger 3	26	0	0	26
AR protein	32	0	0	32
thioredoxin glutathione reductase	7	0	0	7
progesterone receptor	20	0	0	20
regulator of G-protein signaling 4	14	0	0	14
retinoic acid nuclear receptor alpha variant 1	24	0	0	24
retinoid X nuclear receptor alpha	23	0	0	23
farnesoid X nuclear receptor	16	0	0	16
pregnane X nuclear receptor	24	0	0	24
estrogen nuclear receptor alpha	36	0	0	36
peroxisome proliferator-activated receptor delta	17	0	0	17
peroxisome proliferator activated receptor gamma	22	0	0	22
vitamin D (1,25- dihydroxyvitamin D3) receptor	19	0	0	19
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	17	0	0	17
activating transcription factor 6	12	0	0	12
v-jun sarcoma virus 17 oncogene homolog (avian)	15	0	0	15
Caspase-7	7	0	0	7
Bloom syndrome protein isoform 1	12	0	0	12
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	5	0	0	5
phospholipase A2 precursor	0	1	0	1
vitamin D3 receptor isoform VDRA	14	0	0	14
caspase-3	7	0	0	7
heat shock protein beta-1	14	0	0	14
serine/threonine-protein kinase PLK1	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 1	24	0	0	24
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	8	0	0	8
cysteine protease ATG4B isoform a	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	5	0	0	5
DNA polymerase kappa isoform 1	15	0	0	15
histone acetyltransferase KAT2A isoform 1	15	0	0	15
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	2	0	0	2
Free fatty acid receptor 1	0	0	1	1
Prostaglandin G/H synthase 1	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Trypsin	0	1	0	1
Coagulation factor VII	0	2	0	2
Aromatase	0	4	0	4
Tissue factor	0	2	0	2
Prostaglandin G/H synthase 1	0	3	0	3
Peroxisome proliferator-activated receptor gamma	0	0	5	5
Prostaglandin G/H synthase 2	0	1	0	1
Free fatty acid receptor 4	0	0	1	1
acetylcholinesterase	14	0	0	14
NFKB1 protein, partial	6	0	0	6
signal transducer and activator of transcription 6, interleukin-4 induced	2	0	0	2
EWS/FLI fusion protein	7	0	0	7
putative alpha-glucosidase	1	0	0	1
Solute carrier family 22 member 2	0	3	0	5
Solute carrier family 22 member 1	0	6	0	10
Glutamate receptor ionotropic, NMDA 2D	0	4	0	4
Glutamate receptor ionotropic, NMDA 3B	0	4	0	4
Matrix protein 2	0	1	1	2
Matrix protein 2	0	1	2	3
Spike glycoprotein	12	2	4	18
Glutamate receptor ionotropic, NMDA 2A	0	8	1	14
Glutamate receptor ionotropic, NMDA 2B	0	8	1	14
Glutamate receptor ionotropic, NMDA 2C	0	8	1	14
Glutamate receptor ionotropic, NMDA 1	0	5	0	5
Glutamate receptor ionotropic, NMDA 2A	0	5	0	5
Glutamate receptor ionotropic, NMDA 2B	0	5	0	5
Glutamate receptor ionotropic, NMDA 2C	0	4	0	4
Glutamate receptor ionotropic, NMDA 2D	0	8	1	14
Solute carrier family 22 member 1	0	4	0	5
Glutamate receptor ionotropic, NMDA 3A	0	4	0	4
Glutamate receptor ionotropic, NMDA 3B	0	8	1	14
Multidrug and toxin extrusion protein 1	0	4	0	4
Solute carrier family 22 member 2	0	3	0	4
Glutamate receptor ionotropic, NMDA 3A	0	8	1	14
aryl hydrocarbon receptor	14	0	0	14
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	6	0	0	6
POU domain, class 2, transcription factor 1	0	0	0	1
Solute carrier family 22 member 3	0	1	0	1
Phenylethanolamine N-methyltransferase	0	4	0	4
Cytochrome P450 2A6	0	1	0	1
Substance-P receptor	0	1	0	1
Cytochrome P450 2A5	0	1	0	1
Sodium-dependent dopamine transporter	0	10	1	11
Sigma non-opioid intracellular receptor 1	0	3	1	4
Beta-2 adrenergic receptor	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	2	1	3
Chain A, Hyaluronidase, phage associated	0	1	0	1
estrogen-related nuclear receptor alpha	28	0	0	28
nuclear factor erythroid 2-related factor 2 isoform 2	4	0	0	4
Polyphenol oxidase 2	0	4	0	8
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	2
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	3	0	3
Alpha-2B adrenergic receptor	0	10	1	11
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	1	0	2
Solute carrier family 23 member 1	0	1	0	1
Chain A, Ferritin light chain	8	0	0	8
arylsulfatase A	11	0	0	11
cytochrome P450 2C19 precursor	6	0	0	6
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Carbonic anhydrase-like protein, putative	0	0	0	7
nuclear receptor subfamily 1, group I, member 3	20	0	0	20
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	6	0	0	6
short transient receptor potential channel 6 isoform 1	0	0	1	1
ATP-binding cassette sub-family C member 3	0	17	0	17
Multidrug resistance-associated protein 4	0	18	0	19
5-hydroxytryptamine receptor 4	0	12	0	12
Bile salt export pump	0	28	0	28
Muscarinic acetylcholine receptor M2	0	12	1	16
Muscarinic acetylcholine receptor M4	0	12	1	15
Muscarinic acetylcholine receptor M1	0	4	1	7
Muscarinic acetylcholine receptor M3	0	4	1	7
Muscarinic acetylcholine receptor M4	0	4	1	7
Muscarinic acetylcholine receptor M5	0	4	1	7
Muscarinic acetylcholine receptor M5	0	12	1	15
Muscarinic acetylcholine receptor M2	0	4	1	8
Muscarinic acetylcholine receptor M1	0	12	1	16
Muscarinic acetylcholine receptor M1	0	0	0	1
Muscarinic acetylcholine receptor M3	0	12	1	15
Alpha-1D adrenergic receptor	0	12	0	12
5-hydroxytryptamine receptor 2C	0	12	0	12
Muscarinic acetylcholine receptor M4	0	1	0	1
5-hydroxytryptamine receptor 7	0	5	0	5
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	1	1	3
Canalicular multispecific organic anion transporter 1	0	18	0	18
Cytochrome P450 3A4	0	6	0	6
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
D(1A) dopamine receptor	9	0	0	9
Acetylcholine receptor subunit alpha	0	1	0	1
Acetylcholine receptor subunit gamma	0	1	0	1
Integrin alpha-5	0	1	0	1
Acetylcholine receptor subunit beta	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	1	0	2
UDP-glucuronosyltransferase 1-6	0	1	0	1
Cytochrome P450 2B6	0	1	0	3
UDP-glucuronosyltransferase 1A1	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	1	0	3
Sodium-dependent noradrenaline transporter	0	17	2	19
Neuronal acetylcholine receptor subunit beta-4	0	1	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Cytochrome P450 2C19	0	4	0	4
UDP-glucuronosyltransferase 2B10	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	2
Sodium-dependent dopamine transporter	0	18	1	19
Acetylcholine receptor subunit delta	0	1	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
thyroid stimulating hormone receptor	15	0	0	15
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
thyroid hormone receptor beta isoform a	12	0	0	12
muscarinic acetylcholine receptor M1	11	0	0	11
Voltage-dependent calcium channel gamma-2 subunit	7	0	0	7
Glycogen phosphorylase, muscle form	0	2	0	2
Renin	0	2	0	2
Cholinesterase	0	2	0	2
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	7	4	11
Adenosine receptor A3	0	5	0	5
Glutamate receptor 2	8	2	1	11
Amine oxidase [flavin-containing] A	0	4	0	5
Acetylcholinesterase	0	3	0	3
Adenosine receptor A1	0	5	0	11
Amine oxidase [flavin-containing] B	0	6	0	7
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	3	0	3
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	6	3	11
Adenosine receptor A2b	0	2	0	4
Adenosine receptor A2b	0	3	0	5
Adenosine receptor A1	0	7	2	13
Adenosine receptor A2a	0	4	0	12
Vasopressin V2 receptor	0	0	0	2
Serine/threonine-protein kinase mTOR	0	1	0	1
Adenosine receptor A2a	0	2	0	2
Adenosine receptor A1	0	2	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	3	0	3
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
Adenylate cyclase type 1	0	0	0	2
Chitotriosidase-1	0	2	0	2
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
Palmitoleoyl-protein carboxylesterase NOTUM	0	2	3	5
Endochitinase B1	0	2	0	2
Phosphodiesterase	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	5	1	6
Guanine deaminase	0	2	0	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
G	7	0	0	7
histone-lysine N-methyltransferase 2A isoform 2 precursor	5	0	0	5
Interferon beta	11	0	0	11
HLA class I histocompatibility antigen, B alpha chain	7	0	0	7
Inositol hexakisphosphate kinase 1	7	0	0	7
cytochrome P450 2C9, partial	7	0	0	7
Chain A, serum paraoxonase	0	1	0	1
Carbonic anhydrase 3	0	2	0	7
Neutrophil cytosol factor 1	0	1	0	1
Carbonic anhydrase 4	0	6	0	11
Carbonic anhydrase 6	0	3	0	8
Carbonic anhydrase 7	0	3	0	8
Carbonic anhydrase 13	0	1	0	3
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
Carbonic anhydrase 14	0	2	0	7
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
caspase 7, apoptosis-related cysteine protease	9	0	0	9
67.9K protein	9	0	0	9
caspase-3	9	0	0	9
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
thyrotropin-releasing hormone receptor	3	0	0	3
Caspase-2	0	0	1	1
Inositol monophosphatase 1	9	0	0	9
ATPase family AAA domain-containing protein 5	7	0	0	7
Ataxin-2	11	0	0	11
Carbonic anhydrase	0	3	0	8
Carbonic anhydrase 15	0	3	0	8
Chain A, JmjC domain-containing histone demethylation protein 3A	9	0	0	9
Histone H2A.x	8	0	0	8
1,3-beta-D-glucan synthase catalytic subunit	0	1	0	1
Histone deacetylase 3	0	2	0	2
Aldo-keto reductase family 1 member B10	0	1	0	1
Amyloid-beta precursor protein	0	5	0	5
Aldo-keto reductase family 1 member B1	0	12	0	12
Aldo-keto reductase family 1 member B1	0	2	0	2
Tyrosine-protein phosphatase non-receptor type 2	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	3	1	4
Histone deacetylase 4	0	2	0	2
Lactoperoxidase	0	1	0	2
Histone deacetylase 1	0	2	0	2
Integrase	0	2	0	2
Histone deacetylase 7	0	2	0	2
Rap guanine nucleotide exchange factor 4	3	0	0	3
Histone deacetylase 2	0	2	0	2
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Histone deacetylase 8	0	2	0	2
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
large T antigen	0	2	0	2
Proteasome subunit beta type-11	0	0	0	1
ATAD5 protein, partial	9	0	0	9
Fumarate hydratase	6	0	0	6
Thrombopoietin	4	0	0	4
NADPH oxidase 1	0	1	0	1
polyprotein	6	0	0	6
Snq2p	0	0	0	4
Adenylate cyclase type 1	0	2	0	2
Spike glycoprotein	0	2	4	6
Replicase polyprotein 1ab	0	2	4	6
potassium voltage-gated channel subfamily H member 2 isoform d	9	0	0	9
histone deacetylase 9 isoform 3	4	0	0	4
atrial natriuretic peptide receptor 2 precursor	4	0	0	4
ras-related protein Rab-9A	6	0	0	6
serine/threonine-protein kinase mTOR isoform 1	6	0	0	6
M-phase phosphoprotein 8	12	0	0	12
Proteasome subunit alpha type-7	0	0	0	1
Transmembrane protease serine 2	0	2	4	6
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
Bile salt export pump	0	1	0	1
Epidermal growth factor receptor	0	6	0	6
Albumin	0	1	2	3
Albumin	0	0	2	2
Major prion protein	0	0	2	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Major prion protein	0	0	1	1
Cytochrome P450 1A2	0	5	1	7
Tyrosine-protein kinase Fyn	0	5	0	5
Procathepsin L	0	2	4	6
5-hydroxytryptamine receptor 1A	0	2	1	3
Alpha-2A adrenergic receptor	0	10	0	10
Replicase polyprotein 1a	0	2	4	6
Replicase polyprotein 1ab	0	2	4	6
Cys-loop ligand-gated ion channel	0	1	0	1
Cytochrome P450 2D6	0	6	1	7
Cytochrome P450 2C9	0	4	0	5
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Angiotensin-converting enzyme	0	8	0	8
D(2) dopamine receptor	0	14	1	16
Alpha-1B adrenergic receptor	0	7	0	7
Sphingomyelin phosphodiesterase	0	1	0	1
Alpha-2C adrenergic receptor	0	8	0	8
D	0	4	0	4
D(3) dopamine receptor	0	5	0	5
Alpha-2B adrenergic receptor	0	3	0	3
D(2) dopamine receptor	0	1	0	1
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	4	0	4
D(1A) dopamine receptor	0	11	0	13
D(4) dopamine receptor	0	10	0	11
D(1B) dopamine receptor	0	1	0	2
Adenylate cyclase type 3	0	2	0	2
Alpha-2C adrenergic receptor	0	3	0	3
Alpha-2A adrenergic receptor	0	3	0	3
Alpha-1D adrenergic receptor	0	4	0	4
Histamine H2 receptor	0	9	2	11
D(1B) dopamine receptor	0	4	0	4
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	1	0	2
5-hydroxytryptamine receptor 2A	0	11	0	11
Trypanothione reductase	0	4	0	4
D(4) dopamine receptor	0	4	0	4
Histamine H1 receptor	0	2	2	4
Melanocortin receptor 4	0	4	0	4
Melanocortin receptor 5	0	4	0	4
Pleiotropic ABC efflux transporter of multiple drugs	0	4	0	8
5-hydroxytryptamine receptor 7	0	2	0	2
Histamine H1 receptor	0	10	2	12
Mu-type opioid receptor	0	7	0	8
D(3) dopamine receptor	0	12	0	13
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 4 subunit alpha	0	3	0	3
Adenylate cyclase type 8	0	2	0	2
Proteasome subunit beta type-10	0	0	0	1
Delta-type opioid receptor	0	5	0	6
Kappa-type opioid receptor	0	7	0	8
5-hydroxytryptamine receptor 2B	0	12	0	12
Melanocortin receptor 3	0	4	0	4
Alpha-1A adrenergic receptor	0	7	0	7
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
D(1A) dopamine receptor	5	0	0	5
5-hydroxytryptamine receptor 6	0	11	0	11
Cytochrome P450 2J2	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	1	0	1
Proteasome subunit alpha type-6	0	0	2	3
D(2) dopamine receptor	0	7	0	8
Calmodulin	0	1	2	3
Aldehyde oxidase 1	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Adenylate cyclase type 6	0	2	0	2
Adenylate cyclase type 5	0	2	0	2
Aldehyde oxidase	0	2	0	4
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Sodium channel protein type 5 subunit alpha	0	3	0	3
Sodium channel protein type 9 subunit alpha	0	2	0	2
Nuclear receptor subfamily 3 group C member 3	0	8	0	8
Adenylyl cyclase 7	0	2	0	2
Proteasome subunit alpha-type 8	0	0	0	1
D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	3	0	3
Proteasome subunit beta type-7	0	0	0	1
Sigma non-opioid intracellular receptor 1	0	10	0	10
Angiotensin-converting enzyme 2	0	2	4	6
Sodium channel protein type 3 subunit alpha	0	3	0	3
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	2	0	2
Histamine H3 receptor	0	3	2	5
Sodium channel protein type 10 subunit alpha	0	2	0	2
PINK1	1	0	0	1
Parkin	3	0	0	3
bromodomain adjacent to zinc finger domain 2B	10	0	0	10
serine-protein kinase ATM isoform a	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
prostaglandin E2 receptor EP2 subtype	0	0	0	1
Acetylcholinesterase	0	1	0	1
Nuclear receptor ROR-gamma	5	0	0	5
Carboxylic ester hydrolase	0	1	0	1
ORF73	0	0	1	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
General amino-acid permease GAP1	0	0	0	1
Nitric oxide synthase, brain	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Sex hormone-binding globulin	0	0	3	3
Beta-glucuronidase	0	1	0	1
Corticosteroid-binding globulin	0	3	0	3
Beta-glucuronidase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	3	0	3
Alpha-synuclein	4	3	0	7
TAR DNA-binding protein 43	6	0	0	6
G-protein coupled bile acid receptor 1	0	0	2	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	0	1	1
Solute carrier organic anion transporter family member 1A4	0	1	0	4
Solute carrier organic anion transporter family member 1A5	0	0	0	3
Steryl-sulfatase	0	1	0	2
Multidrug resistance-associated protein 1	0	1	0	2
Solute carrier organic anion transporter family member 1A1	0	1	0	2
Solute carrier organic anion transporter family member 1A2	0	0	0	3
Solute carrier organic anion transporter family member 1A3	0	0	0	3
ATP-binding cassette sub-family C member 11	0	0	0	1
Solute carrier organic anion transporter family member 1B3	0	0	0	2
Solute carrier family 22 member 11	0	0	0	1
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier organic anion transporter family member 1B1	0	0	0	3
Thymidine kinase, cytosolic	0	1	0	2
Deoxycytidine kinase	0	0	0	1
AAA family ATPase	0	0	0	1
Sterol O-acyltransferase 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	2	2
Trace amine-associated receptor 1	0	0	2	2
Trace amine-associated receptor 1	0	0	2	2
endonuclease IV	4	0	0	4
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Glutamate receptor 1	1	2	1	4
Glutamate receptor 3	1	2	1	4
Glutamate receptor 4	1	2	1	4
Caspase-7	3	0	0	3
Motilin receptor	0	0	1	1
acid sphingomyelinase	1	0	0	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
streptokinase A precursor	0	0	2	2
Motilin receptor	0	1	1	2
30S ribosomal protein S6	0	1	1	2
30S ribosomal protein S7	0	1	1	2
50S ribosomal protein L15	0	1	1	2
ATP-dependent translocase ABCB1	0	4	0	4
60 kDa chaperonin	0	2	0	2
50S ribosomal protein L10	0	1	1	2
50S ribosomal protein L11	0	1	1	2
50S ribosomal protein L7/L12	0	1	1	2
50S ribosomal protein L19	0	1	1	2
50S ribosomal protein L1	0	1	1	2
50S ribosomal protein L20	0	1	1	2
50S ribosomal protein L27	0	1	1	2
50S ribosomal protein L28	0	1	1	2
50S ribosomal protein L29	0	1	1	2
50S ribosomal protein L31	0	1	1	2
50S ribosomal protein L31 type B	0	1	1	2
50S ribosomal protein L32	0	1	1	2
50S ribosomal protein L33	0	1	1	2
50S ribosomal protein L34	0	1	1	2
50S ribosomal protein L35	0	1	1	2
50S ribosomal protein L36	0	1	1	2
30S ribosomal protein S10	0	1	1	2
30S ribosomal protein S11	0	1	1	2
30S ribosomal protein S12	0	1	1	2
30S ribosomal protein S13	0	1	1	2
30S ribosomal protein S16	0	1	1	2
30S ribosomal protein S18	0	1	1	2
30S ribosomal protein S19	0	1	1	2
30S ribosomal protein S20	0	1	1	2
30S ribosomal protein S2	0	1	1	2
30S ribosomal protein S3	0	1	1	2
30S ribosomal protein S4	0	1	1	2
30S ribosomal protein S5	0	1	1	2
30S ribosomal protein S8	0	1	1	2
30S ribosomal protein S9	0	1	1	2
50S ribosomal protein L13	0	1	1	2
50S ribosomal protein L14	0	1	1	2
50S ribosomal protein L16	0	1	1	2
50S ribosomal protein L23	0	1	1	2
30S ribosomal protein S15	0	1	1	2
50S ribosomal protein L17	0	1	1	2
50S ribosomal protein L21	0	1	1	2
50S ribosomal protein L30	0	1	1	2
50S ribosomal protein L6	0	1	1	2
30S ribosomal protein S14	0	1	1	2
30S ribosomal protein S17	0	1	1	2
30S ribosomal protein S1	0	1	1	2
50S ribosomal protein L18	0	1	1	2
60 kDa heat shock protein, mitochondrial	0	2	0	2
Chitinase B	0	1	0	1
ATP-dependent translocase ABCB1	0	4	1	5
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
50S ribosomal protein L2	0	1	1	2
50S ribosomal protein L3	0	1	1	2
50S ribosomal protein L24	0	1	1	2
50S ribosomal protein L4	0	1	1	2
50S ribosomal protein L22	0	1	1	2
10 kDa heat shock protein, mitochondrial	0	2	0	2
50S ribosomal protein L5	0	1	1	2
30S ribosomal protein S21	0	1	1	2
50S ribosomal protein L25	0	1	1	2
Thiosulfate sulfurtransferase	0	2	0	2
Lanosterol 14-alpha demethylase	0	2	0	2
50S ribosomal protein L36 2	0	1	1	2
60 kDa chaperonin	0	2	0	2
10 kDa chaperonin	0	2	0	2
GALC protein	4	0	0	4
nonstructural protein 1	4	0	0	4
hexokinase-4 isoform 1	2	0	0	2
peripheral myelin protein 22 isoform 1	6	0	0	6
glucokinase regulatory protein	2	0	0	2
Estrogen receptor	0	4	2	8
17-beta-hydroxysteroid dehydrogenase type 1	0	2	0	3
Androgen receptor	0	4	0	4
Mu-type opioid receptor	0	1	1	2
Mu-type opioid receptor	0	0	1	1
Estrogen receptor beta	0	3	2	6
Ghrelin O-acyltransferase	0	1	0	1
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
Asialoglycoprotein receptor 1	0	1	1	2
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Glutathione reductase, mitochondrial	0	4	0	5
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	1	3	4
ATP-citrate synthase	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	2	1	3
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	1	2	3
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	3	0	3
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	2	0	2
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Glutamine synthetase	0	1	0	1
Cytochrome P450 71B1	0	1	0	2
Glutamine synthetase	0	1	0	1
2-dehydro-3-deoxyphosphooctonate aldolase	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Solute carrier family 22 member 3	0	1	0	2
Plasma kallikrein	0	0	0	5
Macrophage migration inhibitory factor	0	4	0	4
Histamine H1 receptor	0	3	1	4
Carbonic anhydrase	0	0	0	6
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	0	0	6
Carbonic anhydrase	0	0	0	6
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carbonic anhydrase 13	0	1	0	5
Histamine H4 receptor	0	2	2	4
Histamine H3 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
Acetylcholinesterase	0	2	0	2
Cholinesterase	0	2	0	2
dopamine D1 receptor	2	0	0	2
integrase, partial	0	2	0	2
lens epithelium-derived growth factor p75	0	2	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	6	0	0	6
pyruvate kinase	1	0	0	1
flap endonuclease 1	7	0	0	7
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
Tyrosine-protein kinase Lck	0	3	0	3
Solute carrier family 15 member 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	5	0	6
SLC16A10 protein	0	0	0	4
Monocarboxylate transporter 10	0	0	0	4
phosphoglycerate kinase	3	0	0	3
heat shock 70kDa protein 1A	0	1	0	1
glyceraldehyde-3-phosphate dehydrogenase isoform 1	0	1	0	1
heat shock cognate 71 kDa protein isoform 1	0	1	0	1
dual specificity protein phosphatase 6	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
heat shock cognate 71 kDa protein isoform 2	0	1	0	1
Glutathione S-transferase Mu 1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
interleukin 8	3	0	0	3
ClpP	1	0	0	1
Cytochrome P450 1A1	0	3	1	4
Cytochrome P450 1A2	0	1	0	1
Myeloperoxidase	0	3	0	3
Cytochrome P450 2C11	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	0	2
Acetylcholinesterase	0	1	0	1
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	0	1
Carboxylic ester hydrolase	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	4	0	0	4
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
PPM1D protein	3	0	0	3
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
hypothetical protein, conserved	1	0	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
luciferase	1	0	0	1
neutrophil cytosol factor 1	0	2	0	2
caspase-9 isoform alpha precursor	0	1	0	1
huntingtin isoform 2	4	0	0	4
pyruvate kinase PKM isoform a	1	0	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
Vpr	1	0	0	1
muscleblind-like protein 1 isoform 1	4	0	0	4
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
neuropeptide S receptor isoform A	6	0	0	6
Glutathione reductase	0	1	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Cruzipain	0	1	0	1
Guanine nucleotide-binding protein G	4	0	0	4
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
Transporter	0	1	0	1
Transporter	0	2	0	2
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
NAD-dependent protein deacetylase HST2	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
Sodium/iodide cotransporter	0	1	0	1
Chain A, CITRATE SYNTHASE	0	0	1	1
Chain B, CITRATE SYNTHASE	0	0	1	1
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	0	1	0	1
Methyl-accepting chemotaxis protein NahY	0	0	1	1
Geranylgeranyl pyrophosphate synthase	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	1
Farnesyl pyrophosphate synthase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	4	0	4
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	3	0	3
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	2	0	2
E3 ubiquitin-protein ligase XIAP	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Phospholipase A-2-activating protein	0	3	0	3
pregnane X receptor	2	0	0	2
DNA polymerase III, partial	3	0	0	3
XBP1	0	1	0	1
DNA damage-inducible transcript 3 protein	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1G	0	0	1	1
Ubiquitin carboxyl-terminal hydrolase 1	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Glycine receptor subunit alpha-1	0	0	1	1
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
Multidrug and toxin extrusion protein 2	0	2	0	2
WD repeat-containing protein 48	0	1	0	1
Hsf1 protein	0	0	1	2
Synaptic vesicle glycoprotein 2A	0	1	0	1
Mcl-1	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	2	0	2
Chloroquine resistance transporter	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, APH(2')-Id	0	1	0	1
glucose-6-phosphate dehydrogenase	0	1	0	1
Nrf2	1	0	0	1
Neuraminidase	0	2	0	2
hexokinase	0	1	0	1
galactokinase	1	0	0	1
interferon gamma precursor	0	0	0	2
cytochrome P450 2C9 precursor	1	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
Maltase-glucoamylase, intestinal	0	1	0	1
NUAK family SNF1-like kinase 1	0	1	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
B2 bradykinin receptor	0	1	0	1
G2/mitotic-specific cyclin-B2	0	1	0	1
Arginase	0	1	0	1
Pancreatic triacylglycerol lipase	0	1	0	1
Prothrombin	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Cationic trypsin	0	1	0	1
Chymotrypsinogen A	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Beta-lactamase	0	1	0	1
Protein E6	0	1	0	1
Neuraminidase	0	1	0	1
Interstitial collagenase	0	1	1	2
Phospholipase A2	0	1	0	1
Beta-lactamase	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Epoxide hydrolase 1	0	1	0	1
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
Tyrosine-protein kinase Yes	0	1	0	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	0	1
Insulin-like growth factor 1 receptor	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	3
Neutrophil elastase	0	2	0	2
72 kDa type IV collagenase	0	2	0	2
Stromelysin-1	0	3	0	3
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Alpha-amylase 1A	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Sialidase	0	1	0	1
Malate dehydrogenase	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 2	0	1	0	1
Serine/threonine-protein kinase pim-1	0	1	1	2
Cyclin-dependent kinase 4	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	2	2
Sucrase-isomaltase, intestinal	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Matrix metalloproteinase-9	0	2	0	2
Urease subunit alpha	0	2	0	2
Serine/threonine-protein kinase B-raf	0	1	0	1
G2/mitotic-specific cyclin-B	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Chymotrypsinogen B	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Casein kinase II subunit alpha'	0	2	0	2
Amine oxidase [flavin-containing] A	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
G1/S-specific cyclin-D1	0	1	0	1
Cyclin-dependent kinase 2	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Cytosol aminopeptidase	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Vasopressin V2 receptor	0	1	0	1
Tyrosine-protein kinase receptor UFO	0	1	0	1
Substance-P receptor	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
RAC-alpha serine/threonine-protein kinase	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Trypsin-3	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Receptor-type tyrosine-protein kinase FLT3	0	2	0	2
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Macrophage metalloelastase	0	2	0	2
Kappa-type opioid receptor	0	1	0	1
Glutathione reductase	0	1	0	1
Tyrosine-protein kinase SYK	0	1	1	2
Collagenase 3	0	2	0	2
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Prolyl endopeptidase	0	1	0	1
Glycogen synthase kinase-3 alpha	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
C-C chemokine receptor type 4	0	1	0	1
Serine/threonine-protein kinase Nek2	0	1	0	1
Oligo-1,6-glucosidase IMA1	0	1	0	1
Serine/threonine-protein kinase PLK1	0	1	0	1
Death-associated protein kinase 1	0	1	0	1
Mitogen-activated protein kinase 10	0	1	0	1
Monocarboxylate transporter 1	0	1	0	1
Beta-secretase 1	0	2	1	3
Anthrax toxin receptor 2	0	1	0	1
Casein kinase II subunit beta	0	2	0	2
Casein kinase II subunit alpha	0	2	0	2
Urease subunit beta	0	2	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	0	3
Cyclin-dependent kinase 6	0	1	0	1
Cyclin-dependent-like kinase 5	0	1	0	1
Heat shock factor protein 1	0	1	0	1
Sorbitol dehydrogenase	0	1	0	1
Cyclin homolog	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	0	1
Lactoylglutathione lyase	0	2	0	2
Focal adhesion kinase 1	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	0	1
ELAV-like protein 3	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
ELAV-like protein 1	0	1	0	1
Serine/threonine-protein kinase N1	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
Carbonic anhydrase 3	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Substance-K receptor	0	1	0	1
Casein kinase II subunit alpha 3	0	2	0	2
Inositol polyphosphate multikinase	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Aldo-keto reductase family 1 member C21	0	2	0	2
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	1	0	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	1	0	1
Chymotrypsin-C	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
Serine/threonine-protein kinase Nek6	0	1	0	1
NADPH oxidase 4	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
ALK tyrosine kinase receptor	0	1	0	1
Sialidase-2	0	1	0	1
hemoglobin subunit beta	1	0	0	1
caspase-1 isoform alpha precursor	2	0	0	2
Quinolone resistance protein NorA	0	1	0	2
DNA topoisomerase 1	0	1	0	1
Chromaffin granule amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	2	1	3
Synaptic vesicular amine transporter	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Ribonuclease HI	0	1	0	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
NPYLR7B	0	0	1	1
tumor necrosis factor	1	0	0	1
Riboflavin-binding protein	0	1	1	2
Neutral amino acid transporter A	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Programmed cell death protein 1	0	1	0	1
Programmed cell death 1 ligand 1	0	1	0	1
Free fatty acid receptor 3	0	0	1	1
Chain A, CES1 protein	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
ubiquitin-conjugating enzyme E2 N	0	1	0	1
Serine/threonine-protein kinase D3	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Estrogen receptor	0	0	1	2
Progesterone receptor	0	1	0	1
Beta-1 adrenergic receptor	0	2	0	2
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Beta-3 adrenergic receptor	0	2	0	2
Protein kinase C alpha type	0	1	0	1
Thromboxane-A synthase	0	1	0	1
Protein kinase C eta type	0	1	0	1
Substance-P receptor	0	2	0	2
B2 bradykinin receptor	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Protein kinase C iota type	0	1	0	1
Estrogen-related receptor gamma	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C theta type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Serine/threonine-protein kinase D1	0	1	0	1
Estrogen receptor beta	0	0	1	2
Protein kinase C eta type	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
Mast/stem cell growth factor receptor Kit	0	1	0	1
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Phosphodiesterase	0	2	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Thyroid hormone receptor beta	0	2	0	2
Adenosine receptor A1	0	2	0	2
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Tryptophan 5-hydroxylase 1	0	1	0	1
Cathepsin D	0	1	0	1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Transthyretin	0	1	0	3
Thyroid hormone receptor alpha	0	2	3	5
Thyroid hormone receptor beta	0	2	3	5
Proliferating cell nuclear antigen	0	2	0	2
Retinoic acid receptor RXR-alpha	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
guanine nucleotide-binding protein subunit alpha-15	0	1	1	2
D(3) dopamine receptor isoform e	1	0	0	1
trace amine-associated receptor 1	0	1	1	2
Dopamine beta-hydroxylase	0	0	0	1
5-hydroxytryptamine receptor 3A	0	0	1	1
Histamine H3 receptor	0	0	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Solute carrier family 22 member 6	0	0	0	1
Solute carrier family 22 member 8	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Cytochrome P450 2E1	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(2)

Research Excerpts

Overview

Actions

Treatment

Research

Studies (222)

Protein Targets (1,197)

Fatigue, Mental

Synonyms(2)

Research Excerpts

Overview

Actions

Treatment

Research

Studies (222)

Drugs Studied (167)

Protein Targets (1,197)