Page last updated: 2024-09-27

Brain Injury, Chronic

Conditions characterized by persistent brain damage or dysfunction as sequelae of cranial trauma. This disorder may result from DIFFUSE AXONAL INJURY; INTRACRANIAL HEMORRHAGES; BRAIN EDEMA; and other conditions. Clinical features may include DEMENTIA; focal neurologic deficits; PERSISTENT VEGETATIVE STATE; AKINETIC MUTISM; or COMA.

Synonyms(2)

Synonym
Chronic Brain Injury
Brain Injury, Chronic

Research Excerpts

Research

Studies (70)

TimeframeStudies, This Condition (%)All Conditions %
pre-19902 (2.86)23.3326
1990's9 (12.86)12.5806
2000's30 (42.86)18.1394
2010's26 (37.14)28.8240
2020's3 (4.29)9.53
DrugIndicatedRelationship StrengthStudiesTrials
choline0low10
lactic acid0low10
melatonin0low20
propionic acid0low10
hydroxyindoleacetic acid0low10
amantadine0medium32
antipyrine0low20
baclofen0low10
benserazide0low10
carbamazepine0low10
amphetamine0low10
donepezil0medium11
fluoxetine0low10
glyphosate0low30
edaravone0low30
meclofenoxate0low20
methylphenidate0medium11
modafinil0low10
ondansetron0medium11
pirenzepine0low10
ono 10780low10
riluzole0low10
corticosterone0low10
triiodothyronine0low10
aspartic acid0low10
methyltestosterone0low10
bromodeoxyuridine0low10
mannitol0low10
tryptophan0low10
tetraethoxysilane0low10
methylprednisolone0low10
quinoxalines0low10
nandrolone0low10
n-methylaspartate0low10
xenon0low10
phenyl acetate0low20
epirubicin0low10
fomesafen0low10
adenosine0low10
n-acetylaspartic acid0low10
fluorodeoxyglucose f180low50
rivastigmine0medium11
nicotine0low10
droxidopa0low10
varenicline0low10
angiotensin ii0low10
cyclo(glycylprolyl)0low10
ramelteon0low10
inositol 3-phosphate0low10
enkephalin, leucine0low10
apigenin0low10
montelukast0low10
glyceryl 2-arachidonate0low10
4-hydroxy-2-hexenal0low10
4-hydroxy-2-nonenal0low10
pd 1233190low10
alpha-synuclein0low10
cytochrome c-t0low10
cosyntropin0low10
neuropeptide y0low10
florbetapir f 180low10
piperidines0medium11
amyloid beta-peptides0low10
neopterin0low10
olanzapine0low10

Protein Targets (828)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Microtubule-associated protein tau7007
vitamin D3 receptor isoform VDRA6006
Transient receptor potential cation channel subfamily A member 10011
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE6006
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
AR protein200020
signal transducer and activator of transcription 6, interleukin-4 induced2002
regulator of G-protein signaling 4110011
glucocorticoid receptor [Homo sapiens]150015
retinoid X nuclear receptor alpha100010
estrogen nuclear receptor alpha210021
NPYLR7B0011
arylsulfatase A9009
IDH19009
Histone H2A.x7007
glycogen synthase kinase-3 beta isoform 10022
mitogen-activated protein kinase 16006
flap endonuclease 15005
nuclear receptor ROR-gamma isoform 14004
peripheral myelin protein 228008
survival motor neuron protein isoform d6006
high affinity choline transporter 1 isoform a0101
Sodium/nucleoside cotransporter 10202
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70011
Sodium/nucleoside cotransporter 20202
Voltage-dependent calcium channel gamma-2 subunit7007
Rap guanine nucleotide exchange factor 32002
Purine nucleoside phosphorylase0101
Epidermal growth factor receptor0202
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0202
Receptor tyrosine-protein kinase erbB-20101
Insulin receptor0001
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha0112
Platelet-derived growth factor receptor beta0001
Adenosine receptor A30427
Heat shock 70 kDa protein 1A 0101
Heat shock cognate 71 kDa protein0011
Fibroblast growth factor receptor 10001
Inosine-5'-monophosphate dehydrogenase 20101
Endoplasmin0112
Glutamate receptor 27108
Inosine-5'-monophosphate dehydrogenase 1 0101
Fibroblast growth factor receptor 20001
Fibroblast growth factor receptor 40001
Fibroblast growth factor receptor 30001
Streptavidin0011
Adenosylhomocysteinase0001
Adenosine receptor A10213
Adenosine receptor A30101
Adenosine receptor A2a0124
Adenosine receptor A2b0012
Adenosine receptor A2b0112
Adenylate kinase 2, mitochondrial0101
Adenosine receptor A10427
Adenosine receptor A2a0112
Adenylate kinase isoenzyme 1 0101
Phosphatidylinositol 4-kinase alpha0203
Adenosine receptor A10011
Adenosine kinase0001
Adenosine deaminase 0001
Equilibrative nucleoside transporter 20202
Phosphatidylinositol 4-kinase type 2-beta0203
Histone-lysine N-methyltransferase, H3 lysine-79 specific0101
Equilibrative nucleoside transporter 10202
Phosphatidylinositol 4-kinase type 2-alpha0203
Solute carrier family 28 member 30202
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta0203
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
acetylcholinesterase7007
thioredoxin reductase140014
RAR-related orphan receptor gamma120012
NFKB1 protein, partial6006
GLI family zinc finger 3150015
thyroid stimulating hormone receptor7007
EWS/FLI fusion protein9009
putative alpha-glucosidase1001
euchromatic histone-lysine N-methyltransferase 2190019
thyroid hormone receptor beta isoform 2110011
heat shock protein beta-13003
histone acetyltransferase KAT2A isoform 16006
lamin isoform A-delta10150015
Solute carrier family 22 member 20305
Solute carrier family 22 member 1 0407
Glutamate receptor ionotropic, NMDA 2D0101
Glutamate receptor ionotropic, NMDA 3B0101
Matrix protein 20112
Matrix protein 20123
Glutamate receptor ionotropic, NMDA 1 0417
Spike glycoprotein7007
Glutamate receptor ionotropic, NMDA 2A 0417
Glutamate receptor ionotropic, NMDA 2B0417
Glutamate receptor ionotropic, NMDA 2C0518
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, NMDA 2B0101
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 2D0417
Solute carrier family 22 member 10506
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0417
Multidrug and toxin extrusion protein 10202
Solute carrier family 22 member 20506
Glutamate receptor ionotropic, NMDA 3A0417
ATP-dependent phosphofructokinase100010
Solute carrier family 22 member 30202
5-hydroxytryptamine receptor 2C0617
Phenylethanolamine N-methyltransferase0202
Cytochrome P450 2A60314
Substance-P receptor0101
5-hydroxytryptamine receptor 2A0617
5-hydroxytryptamine receptor 1A0516
Cytochrome P450 2A50202
Sodium-dependent dopamine transporter0606
5-hydroxytryptamine receptor 1B0213
5-hydroxytryptamine receptor 1D0213
5-hydroxytryptamine receptor 1F0213
5-hydroxytryptamine receptor 2B0617
5-hydroxytryptamine receptor 60112
5-hydroxytryptamine receptor 7 0112
5-hydroxytryptamine receptor 5A0112
5-hydroxytryptamine receptor 5B0112
5-hydroxytryptamine receptor 3A0224
Sigma non-opioid intracellular receptor 10516
5-hydroxytryptamine receptor 4 0112
Beta-2 adrenergic receptor0202
5-hydroxytryptamine receptor 3B0224
Sigma non-opioid intracellular receptor 10303
glucocerebrosidase6006
DNA polymerase kappa isoform 14004
Atrial natriuretic peptide receptor 30101
Type-1A angiotensin II receptor 0314
Type-1 angiotensin II receptor0011
Type-1B angiotensin II receptor0303
Type-1 angiotensin II receptor0325
Type-2 angiotensin II receptor0303
Type-2 angiotensin II receptor0303
ATAD5 protein, partial7007
USP1 protein, partial7007
nuclear receptor subfamily 1, group I, member 3110011
retinoic acid nuclear receptor alpha variant 1150015
67.9K protein5005
peroxisome proliferator-activated receptor delta7007
chromobox protein homolog 1120012
thyroid hormone receptor beta isoform a8008
nuclear factor erythroid 2-related factor 2 isoform 27007
nuclear factor erythroid 2-related factor 2 isoform 1120012
geminin210021
ATP-binding cassette sub-family C member 3013013
Multidrug resistance-associated protein 4013013
Bile salt export pump016016
Cytochrome P450 2C9 0404
Cytochrome P450 2J20303
Nicotinate phosphoribosyltransferase0101
Canalicular multispecific organic anion transporter 1013013
Chain A, TYROSYL-DNA PHOSPHODIESTERASE4004
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Chain A, HADH2 protein5005
Chain B, HADH2 protein5005
Chain A, 2-oxoglutarate Oxygenase5005
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0101
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0101
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0101
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0101
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0101
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0101
Chain A, Cruzipain2002
Chain A, Transthyretin0011
Chain A, Transthyretin0011
Chain A, Transthyretin0011
Chain A, Transthyretin0011
Chain B, Transthyretin0011
Chain A, Transthyretin0011
Chain B, Transthyretin0011
Chain A, Casein kinase II subunit alpha0101
Chain A, Casein kinase II subunit alpha0101
Chain A, Casein Kinase Ii Subunit Alpha0101
Luciferase4004
interleukin 84004
endonuclease IV2002
BRCA11001
RGS121001
15-lipoxygenase, partial2002
phosphopantetheinyl transferase7007
hypoxia-inducible factor 1 alpha subunit5005
GLS protein7007
PPM1D protein3003
TDP1 protein110011
Thrombopoietin2002
Smad34004
apical membrane antigen 1, AMA12002
aldehyde dehydrogenase 1 family, member A1120012
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
estrogen receptor 2 (ER beta)6006
progesterone receptor9009
cytochrome P450 family 3 subfamily A polypeptide 48008
estrogen-related nuclear receptor alpha180018
farnesoid X nuclear receptor5005
pregnane X nuclear receptor120012
G7007
cytochrome P450 2D67007
Neuraminidase 0202
Parkin2002
peroxisome proliferator activated receptor gamma8008
vitamin D (1,25- dihydroxyvitamin D3) receptor5005
pyruvate kinase2002
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
aryl hydrocarbon receptor8008
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a9009
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
v-jun sarcoma virus 17 oncogene homolog (avian)7007
Replicase polyprotein 1ab0101
cytochrome P450 2D6 isoform 13003
NPC intracellular cholesterol transporter 1 precursor3003
peripheral myelin protein 22 isoform 15005
hemoglobin subunit beta1001
cellular tumor antigen p53 isoform a4004
cytochrome P450 2C19 precursor4004
cytochrome P450 2C9 precursor3003
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
histone deacetylase 9 isoform 32002
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 11001
ubiquitin carboxyl-terminal hydrolase 2 isoform a4004
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
DNA polymerase eta isoform 11001
DNA polymerase iota isoform a (long)4004
cytochrome P450 3A4 isoform 17007
M-phase phosphoprotein 85005
pyruvate kinase PKM isoform b2002
neuropeptide S receptor isoform A3003
Gamma-aminobutyric acid receptor subunit pi0303
Gamma-aminobutyric acid receptor subunit pi73111
Gamma-aminobutyric acid receptor subunit delta0303
Polyphenol oxidase 20101
Aldo-keto reductase family 1 member B100202
G2/mitotic-specific cyclin-B20101
Poly [ADP-ribose] polymerase tankyrase-10101
Lysozyme C-10101
Cationic trypsin0101
Carbonic anhydrase 10103
Carbonic anhydrase 20103
Interferon beta9009
HLA class I histocompatibility antigen, B alpha chain 7007
Transthyretin0012
Estrogen receptor0101
Glucocorticoid receptor0405
Cellular tumor antigen p53100010
Cytochrome P450 1A10303
Amyloid-beta precursor protein0404
Integrin beta-33104
Myeloperoxidase0303
Cytochrome P450 1A20404
Cyclin-dependent kinase 10101
Beta-glucuronidase0101
Aldo-keto reductase family 1 member B10707
Seed linoleate 13S-lipoxygenase-10103
ATP-dependent translocase ABCB10214
Neutrophil elastase0202
Integrin alpha-IIb3104
Ornithine decarboxylase2002
Poly [ADP-ribose] polymerase 10101
Replicase polyprotein 1a0101
Replicase polyprotein 1ab0101
Replicase polyprotein 1ab0101
Replicase polyprotein 1ab0202
Androgen receptor0203
Sialidase0101
Serine/threonine-protein kinase pim-10102
Aromatase0202
Angiotensin-converting enzyme0404
Cystic fibrosis transmembrane conductance regulator0112
17-beta-hydroxysteroid dehydrogenase type 10101
Pyruvate kinase PKM0101
G2/mitotic-specific cyclin-B10101
Gamma-aminobutyric acid receptor subunit alpha-10303
Urease subunit alpha0101
Aldo-keto reductase family 1 member B10101
G2/mitotic-specific cyclin-B0101
Gamma-aminobutyric acid receptor subunit beta-173111
Mucin-10101
Glycogen synthase kinase-3 beta0101
Gamma-aminobutyric acid receptor subunit beta-10303
Gamma-aminobutyric acid receptor subunit delta73111
Gamma-aminobutyric acid receptor subunit gamma-20303
Gamma-aminobutyric acid receptor subunit gamma-273212
Casein kinase II subunit alpha'0101
Gamma-aminobutyric acid receptor subunit alpha-573111
Gamma-aminobutyric acid receptor subunit alpha-373111
Amine oxidase [flavin-containing] A0202
Acetylcholinesterase0729
Carbonic anhydrase 40102
Gamma-aminobutyric acid receptor subunit gamma-173111
Gamma-aminobutyric acid receptor subunit alpha-273111
Amine oxidase [flavin-containing] B0202
Dipeptidyl peptidase 40101
Proteasome subunit beta type-50101
Gamma-aminobutyric acid receptor subunit alpha-473111
Gamma-aminobutyric acid receptor subunit beta-30303
Gamma-aminobutyric acid receptor subunit gamma-373111
Gamma-aminobutyric acid receptor subunit alpha-673111
Substance-P receptor0202
Gamma-aminobutyric acid receptor subunit alpha-50303
Multidrug resistance-associated protein 1 0101
Gamma-aminobutyric acid receptor subunit alpha-30303
Prostaglandin G/H synthase 20101
Mu-type opioid receptor0214
Receptor-type tyrosine-protein kinase FLT30101
Testosterone 17-beta-dehydrogenase 30101
17-beta-hydroxysteroid dehydrogenase type 20101
Acetylcholinesterase0303
Peroxisome proliferator-activated receptor gamma0011
Delta-type opioid receptor0315
Kappa-type opioid receptor0113
Homeobox protein Nkx-2.5 0101
Tyrosine-protein kinase SYK0213
Histamine H2 receptor3003
Gamma-aminobutyric acid receptor subunit alpha-20303
Gamma-aminobutyric acid receptor subunit beta-20303
Xanthine dehydrogenase/oxidase0202
Gamma-aminobutyric acid receptor subunit alpha-40303
Glycogen synthase kinase-3 alpha0101
Glycogen synthase kinase-3 beta0202
Estrogen receptor0011
Nuclear receptor ROR-gamma6006
Death-associated protein kinase 10101
Mitogen-activated protein kinase 100101
Beta-secretase 10304
Gamma-aminobutyric acid receptor subunit alpha-173212
Gamma-aminobutyric acid receptor subunit beta-373111
Gamma-aminobutyric acid receptor subunit beta-273212
Casein kinase II subunit beta0101
Casein kinase II subunit alpha0202
Urease subunit beta0101
Gamma-aminobutyric acid receptor subunit epsilon0303
Disintegrin and metalloproteinase domain-containing protein 174004
Lactoperoxidase0101
Xanthine dehydrogenase/oxidase0101
MO15-related protein kinase Pfmrk 0101
Inositol monophosphatase 14004
Cyclin-dependent kinase 60101
Cyclin-dependent-like kinase 5 0101
Cyclin homolog0101
Transcription factor GATA-4 0101
Cyclin-dependent kinase 5 activator 10101
Gamma-aminobutyric acid receptor subunit alpha-60303
Mitogen-activated protein kinase 140202
Cytochrome P450 1B10505
Carbonic anhydrase 30101
Substance-K receptor0101
Reverse transcriptase/RNaseH 0101
Integrase 0101
Gamma-aminobutyric acid receptor subunit gamma-10303
Casein kinase II subunit alpha 30101
Inositol polyphosphate multikinase0101
G2/mitotic-specific cyclin-B30101
GABA theta subunit73111
Inositol hexakisphosphate kinase 17007
Estrogen receptor beta0101
Enoyl-acyl-carrier protein reductase 0101
Aurora kinase B0101
NACHT, LRR and PYD domains-containing protein 3 0101
ATPase family AAA domain-containing protein 55005
Ataxin-26006
Gamma-aminobutyric acid receptor subunit gamma-30303
Myocilin0011
Cyclin-dependent kinase 10101
Gamma-aminobutyric acid receptor subunit epsilon73111
Prenyltransferase homolog0001
Poly [ADP-ribose] polymerase tankyrase-20101
MAP kinase-interacting serine/threonine-protein kinase 20101
Carboxylic ester hydrolase 0303
NADPH oxidase 40101
Dipeptidyl peptidase 30101
Estrogen receptor beta0011
Inositol hexakisphosphate kinase 20101
Short transient receptor potential channel 50101
Gamma-aminobutyric acid receptor subunit theta0303
Broad substrate specificity ATP-binding cassette transporter ABCG20101
Sialidase-20101
cytochrome P450 2C9, partial7007
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Chain A, Ferritin light chain1001
Bloom syndrome protein isoform 15005
lethal factor (plasmid)3003
Metabotropic glutamate receptor 60011
Excitatory amino acid transporter 40101
Glutamate transporter homolog0011
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
5-hydroxytryptamine receptor 1D0001
Excitatory amino acid transporter 10101
Excitatory amino acid transporter 20101
Excitatory amino acid transporter 30101
Metabotropic glutamate receptor 10011
Metabotropic glutamate receptor 20011
Carbonic anhydrase-like protein, putative0002
Carbonic anhydrase 40001
activating transcription factor 63003
D(1A) dopamine receptor4004
Gamma-aminobutyric acid type B receptor subunit 20213
Gamma-aminobutyric acid type B receptor subunit 20202
Gamma-aminobutyric acid type B receptor subunit 10213
Gamma-aminobutyric acid type B receptor subunit 10101
serine/threonine-protein kinase mTOR isoform 14004
Zinc finger protein mex-50011
POsterior Segregation0011
Genome polyprotein0101
D(1A) dopamine receptor2002
Hexokinase-20101
pregnane X receptor3003
bromodomain adjacent to zinc finger domain 2B3003
nuclear receptor subfamily 1, group I, member 22002
Nuclear hormone receptor family member daf-120011
oxysterols receptor LXR-beta isoform 10011
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
muscarinic acetylcholine receptor M15005
Thymidine kinase, cytosolic0101
Thymidine phosphorylase0001
Thymidylate kinase0101
Thymidine kinase0001
Thymidylate kinase0101
Chain A, Beta-lactamase1001
Vpr1001
Bile salt export pump0202
Albumin0022
Major prion protein0011
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 2 subunit alpha0202
Sodium channel protein type 3 subunit alpha0101
UDP-glucuronosyltransferase 2B70003
Cytochrome P450 2B60011
Sodium channel protein type 4 subunit alpha0102
Potassium voltage-gated channel subfamily H member 20909
Sodium channel protein type 9 subunit alpha0202
Frizzled-80011
P2X purinoceptor 40101
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10102
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-30539
Neuronal acetylcholine receptor subunit alpha-416311
Neuronal acetylcholine receptor subunit alpha-20427
Neuronal acetylcholine receptor subunit beta-215310
Neuronal acetylcholine receptor subunit beta-30337
Neuronal acetylcholine receptor subunit beta-40539
Neuronal acetylcholine receptor subunit alpha-50326
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0102
Neuronal acetylcholine receptor subunit alpha-60337
Neuronal acetylcholine receptor subunit alpha-90326
Neuronal acetylcholine receptor subunit alpha-70539
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100326
GALC protein2002
nonstructural protein 13003
thyroid stimulating hormone receptor5005
Solute carrier family 22 member 30202
Sex hormone-binding globulin0033
Corticosteroid-binding globulin0202
Mineralocorticoid receptor 0011
Androgen receptor0707
C-8 sterol isomerase0101
Solute carrier organic anion transporter family member 1A10101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Sigma non-opioid intracellular receptor 10404
Acetylcholinesterase0303
Voltage-dependent L-type calcium channel subunit alpha-1F0101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Acetylcholinesterase0202
Cholinesterase0404
Cytochrome P450 3A40606
Amine oxidase [flavin-containing] B0202
Amine oxidase [flavin-containing] A 0202
Amine oxidase [flavin-containing] A 0101
Acetylcholinesterase0404
Liver carboxylesterase 10101
Acetylcholinesterase 0404
Sodium-dependent serotonin transporter09211
Cholinesterase0314
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Cholinesterase0202
Acetylcholine receptor subunit epsilon0112
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Acyl-CoA:cholesterol acyltransferase 0101
Carboxylic ester hydrolase 0404
Histamine H3 receptor0303
Nuclear receptor subfamily 1 group I member 20022
Nuclear receptor subfamily 1 group I member 20022
SMAD family member 24004
SMAD family member 34004
caspase 7, apoptosis-related cysteine protease3003
caspase-33003
lysosomal alpha-glucosidase preproprotein3003
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
replicative DNA helicase0001
recombinase A0011
UDP-glucuronosyltransferase 1A90002
UDP-glucuronosyltransferase 2B170001
UDP-glucuronosyltransferase 1-60001
UDP-glucuronosyltransferase 1A1 0102
UDP-glucuronosyltransferase 1A70001
Opioid receptor, delta 1b 0101
Opioid receptor homologue0101
Proenkephalin-B0011
Delta-type opioid receptor0517
Delta-type opioid receptor0404
Kappa-type opioid receptor0101
Mu-type opioid receptor0505
Kappa-type opioid receptor0202
Kappa-type opioid receptor0101
Mu-type opioid receptor0101
Mu-type opioid receptor0404
Mu-type opioid receptor0101
Genome polyprotein 0101
Fumarate hydratase3003
polyprotein3003
Tyrosine-protein kinase Fyn0202
Caspase-71001
potassium voltage-gated channel subfamily H member 2 isoform d4004
caspase-31001
huntingtin isoform 21001
atrial natriuretic peptide receptor 2 precursor1001
ras-related protein Rab-9A3003
Sodium-dependent noradrenaline transporter0101
5-hydroxytryptamine receptor 40404
Potassium channel subfamily K member 20112
Muscarinic acetylcholine receptor M50606
Alpha-2A adrenergic receptor0505
Cytochrome P450 2C80202
Cytochrome P450 2D60303
Muscarinic acetylcholine receptor M107210
Dipeptidyl peptidase 40101
Alpha-1B adrenergic receptor0606
Alpha-2B adrenergic receptor0404
Alpha-2B adrenergic receptor0202
Muscarinic acetylcholine receptor M30808
Alpha-2C adrenergic receptor0202
Alpha-2A adrenergic receptor0303
Prostaglandin G/H synthase 10101
Alpha-1D adrenergic receptor0404
Sodium-dependent noradrenaline transporter 010111
Potassium voltage-gated channel subfamily C member 10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
5-hydroxytryptamine receptor 2A0505
5-hydroxytryptamine receptor 2C0404
Sodium-dependent serotonin transporter0505
Cytochrome P450 2C190303
Alpha-1A adrenergic receptor0707
5-hydroxytryptamine receptor 60405
D(2) dopamine receptor0404
Gastrin/cholecystokinin type B receptor 0101
Sodium-dependent dopamine transporter 0819
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Sigma intracellular receptor 20101
Sodium-dependent serotonin transporter0101
Sodium-dependent dopamine transporter0101
Transporter0303
Nuclear receptor subfamily 3 group C member 3 0303
Transporter0517
alpha-galactosidase2002
Fatty-acid amide hydrolase 10101
Fatty acid-binding protein, liver0101
Cannabinoid receptor 10101
Cannabinoid receptor 10112
Cannabinoid receptor 2 0112
Cannabinoid receptor 20101
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase0101
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase0101
Glutamine synthetase 0101
Cytochrome P450 71B10102
Glutamine synthetase 0101
2-dehydro-3-deoxyphosphooctonate aldolase0101
hypothetical protein, conserved1001
Uracil nucleotide/cysteinyl leukotriene receptor0404
lethal(3)malignant brain tumor-like protein 1 isoform I1001
TAR DNA-binding protein 434004
ClpP1001
Cytochrome P450 1A2 0101
Cytochrome P450 2C11 0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0202
Metabotropic glutamate receptor 10101
Nociceptin receptor0101
Melatonin receptor type 1A0314
Melatonin receptor type 1C0011
Melatonin receptor type 1A0112
Melatonin receptor type 1B0314
Melatonin receptor type 1C0112
Melatonin receptor type 1B0112
Nuclear factor erythroid 2-related factor 20001
Palmitoleoyl-protein carboxylesterase NOTUM0101
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
Large neutral amino acids transporter small subunit 10202
muscleblind-like protein 1 isoform 12002
Glycine receptor subunit alpha-10404
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
transcriptional regulator ERG isoform 32002
thioredoxin glutathione reductase2002
D(2) dopamine receptor0404
D(4) dopamine receptor0303
D(3) dopamine receptor0505
Beta-2 adrenergic receptor0202
Beta-3 adrenergic receptor0202
Alpha-2C adrenergic receptor0404
Substance-K receptor0202
Thromboxane-A synthase 0101
5-hydroxytryptamine receptor 2B0606
Leukotriene C4 synthase0101
Cysteinyl leukotriene receptor 10202
Cysteinyl leukotriene receptor 20202
Cysteinyl leukotriene receptor 10314
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Rap guanine nucleotide exchange factor 41001
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Glutamate receptor 10101
Glutamate receptor 30101
Glutamate receptor 40101
Glutamate receptor ionotropic, kainate 10101
Glutamate receptor ionotropic, kainate 20101
Glutamate receptor ionotropic, kainate 30101
Glutamate receptor ionotropic, kainate 40101
Glutamate receptor ionotropic, kainate 50101
5-hydroxytryptamine receptor 70202
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial0101
Neuropeptide Y receptor type 10202
Neuropeptide Y receptor type 20202
5-hydroxytryptamine receptor 3E0315
Neuronal acetylcholine receptor subunit alpha-40213
Transient receptor potential cation channel subfamily A member 10011
5-hydroxytryptamine receptor 3B0315
Acetylcholine receptor subunit alpha0426
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit beta0213
Acetylcholine receptor subunit gamma0213
Acetylcholine receptor subunit delta0213
Acetylcholine receptor subunit gamma0426
Muscarinic acetylcholine receptor M10404
Muscarinic acetylcholine receptor M30404
Muscarinic acetylcholine receptor M40505
Muscarinic acetylcholine receptor M50303
Neuronal acetylcholine receptor subunit alpha-40101
Muscarinic acetylcholine receptor M20404
Acetylcholine receptor subunit beta0426
Translocator protein0101
Neuronal acetylcholine receptor subunit beta-20628
Acetylcholine receptor subunit beta-like 20202
Neuronal acetylcholine receptor subunit alpha-50022
Neuronal acetylcholine receptor subunit beta-40527
Muscarinic acetylcholine receptor M40303
Neuronal acetylcholine receptor subunit alpha-30527
Neuronal acetylcholine receptor subunit alpha-70325
Neuronal acetylcholine receptor subunit alpha-40628
5-hydroxytryptamine receptor 3A0416
Neuronal acetylcholine receptor subunit alpha-70303
Acetylcholine-binding protein0112
Neuronal acetylcholine receptor subunit beta-30112
Acetylcholine receptor subunit delta0426
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit alpha-60112
Cytochrome P450 2A130112
Neuronal acetylcholine receptor subunit alpha-50202
Liver carboxylesterase B-10101
5-hydroxytryptamine receptor 3D0315
Transient receptor potential cation channel subfamily A member 10011
Neuronal acetylcholine receptor subunit beta-30202
Neuronal acetylcholine receptor subunit beta-40202
Neuronal acetylcholine receptor subunit alpha-30202
Soluble acetylcholine receptor0101
5-hydroxytryptamine receptor 3C0315
Neuronal acetylcholine receptor subunit alpha-20202
Neuronal acetylcholine receptor subunit beta-20213
Neuronal acetylcholine receptor subunit alpha-60202
Integrin beta0011
Glycoprotein IIb0011
FAD-linked sulfhydryl oxidase ALR0001
Muscarinic acetylcholine receptor M20303
Muscarinic acetylcholine receptor M40404
5-hydroxytryptamine receptor 1A0213
Glucose-6-phosphate 1-dehydrogenase0101
Polyunsaturated fatty acid lipoxygenase ALOX150101
D0202
D(3) dopamine receptor0202
D(1A) dopamine receptor0202
UDP-glucuronosyltransferase 1A40001
Alpha-1D adrenergic receptor0202
D(4) dopamine receptor0202
Histamine H1 receptor0101
5-hydroxytryptamine receptor 70202
Alpha-1A adrenergic receptor0101
Histamine H1 receptor0213
Alpha-1B adrenergic receptor0101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
5-hydroxytryptamine receptor 3A0011
Beta-2 adrenergic receptor0101
Beta-1 adrenergic receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Interleukin-6 receptor subunit alpha0101
5-hydroxytryptamine receptor 3A0101
D(1B) dopamine receptor0101
Beta-3 adrenergic receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Cholecystokinin receptor type A0101
Gastrin/cholecystokinin type B receptor0101
Histamine H1 receptor0101
Thyrotropin-releasing hormone receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Glycine receptor subunit alpha-40101
Multidrug and toxin extrusion protein 20101
5-hydroxytryptamine receptor 3B0101
Histamine H3 receptor0101
Leukotriene B4 receptor 10101
Nischarin0101
Cruzipain0101
Canalicular multispecific organic anion transporter 10101
Bile acid receptor0011
dopamine D1 receptor1001
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor DM10101
Muscarinic acetylcholine receptor0101
Muscarinic acetylcholine receptor M50101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M20101
Free fatty acid receptor 30011
Free fatty acid receptor 20112
Free fatty acid receptor 20011
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Dihydrofolate reductase0303
Alpha-synuclein1001
Pteridine reductase 10202
Acyl-CoA desaturase 10101
Acetylcholine receptor subunit epsilon0101
Cholinesterase0101
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
glp-1 receptor, partial1001
Solute carrier organic anion transporter family member 1A40102
Solute carrier organic anion transporter family member 1A50001
Prothrombin0011
Thyroid hormone receptor alpha0224
Thyroid hormone receptor beta0224
Proliferating cell nuclear antigen0101
Thyroid hormone receptor beta0101
Peroxisome proliferator-activated receptor gamma0022
Solute carrier organic anion transporter family member 1A20001
Solute carrier organic anion transporter family member 1A30001
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 4A10001
Solute carrier organic anion transporter family member 1C10101
Solute carrier organic anion transporter family member 1B30001
Solute carrier organic anion transporter family member 1B10001
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Carbonic anhydrase 120001
Plasma kallikrein0001
Alkaline phosphatase, tissue-nonspecific isozyme0101
Carbonic anhydrase 30001
Stromelysin-10101
Intestinal-type alkaline phosphatase0101
Indoleamine 2,3-dioxygenase 10102
Carbonic anhydrase 60001
Carbonic anhydrase 5A, mitochondrial0001
Carbonic anhydrase0001
Carbonic anhydrase 70001
Tryptophan 2,3-dioxygenase0102
Carbonic anhydrase0001
SLC16A10 protein0001
Carbonic anhydrase 90001
Carbonic anhydrase 0001
Tryprostatin B synthase0001
Carbonic anhydrase0001
Carbonic anhydrase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Carbonic anhydrase 0001
Monocarboxylate transporter 100001
Carbonic anhydrase 150001
Carbonic anhydrase 130001
Carbonic anhydrase 140001
Phospholipase A-2-activating protein0101
Carbonic anhydrase 5B, mitochondrial0001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]