Page last updated: 2024-10-28

glyphosate and Innate Inflammatory Response

glyphosate has been researched along with Innate Inflammatory Response in 14 studies

glyphosate: active cpd in herbicidal formulation Roundup; inhibits EC 2.5.1.19, 5-enolpyruvylshikimate-3-phosphate synthase; structure
glyphosate : A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).

Research Excerpts

ExcerptRelevanceReference
"We aimed to assess whether lifetime exposure to glyphosate and its degradation product, aminomethylphosphonic acid (AMPA), is associated with elevated liver transaminases and metabolic syndrome among young adults."8.31Association of Lifetime Exposure to Glyphosate and Aminomethylphosphonic Acid (AMPA) with Liver Inflammation and Metabolic Syndrome at Young Adulthood: Findings from the CHAMACOS Study. ( Bradman, A; Eskenazi, B; Gunier, RB; Harley, KG; Holland, N; Kogut, K; Limbach, C; Mendez, X; Mills, PJ; Mora, AM; Perito, ER; Rauch, S, 2023)
"The aim of the present study was to investigate the impacts of glyphosate herbicide on the survival and proliferation of glioblastoma cells and to explore the molecular mechanisms underlying such effects."8.31Glyphosate-induced glioblastoma cell proliferation: Unraveling the interplay of oxidative, inflammatory, proliferative, and survival signaling pathways. ( Bianco, CD; Dos Santos, DC; Kviecisnki, MR; Ourique, F; Pedrosa, RC; Zamoner, A, 2023)
"Maternal exposure to glyphosate affected insulin sensitivity and caused hepatic inflammation in adult F1 mice offspring."8.12Exposure to glyphosate-based herbicide during early stages of development increases insulin sensitivity and causes liver inflammation in adult mice offspring. ( Alegre-Maller, ACP; Amorim, JPA; Balbo, SL; Bonfleur, ML; Gomes, ECZ; Teleken, JL; Vargas, R, 2022)
"Glyphosate has been detected in urine, blood and maternal milk and has been found to induce the generation of reactive oxygen species (ROS) and several cytotoxic and genotoxic effects in vitro and in animal models directly or indirectly through its metabolite, aminomethylphosphonic acid (AMPA)."6.72Pleiotropic Outcomes of Glyphosate Exposure: From Organ Damage to Effects on Inflammation, Cancer, Reproduction and Development. ( Marino, M; Meccariello, R; Mele, E; Nori, SL; Santoro, A; Viggiano, A, 2021)
"Glyphosate is an active ingredient in herbicides."5.91Adhesion Molecules in Lung Inflammation from Repeated Glyphosate Exposures. ( Aulakh, G; Kirychuk, S; Pandher, U; Schneberger, D; Sethi, RS; Singh, B; Thompson, B, 2023)
"Nonalcoholic fatty liver disease (NAFLD), which is linked to western diet (WD) intake, affects 30% of the world's population and involves the crosstalk of liver steatosis, hypertrophy/inflammation of adipose tissue and deregulation of gut microbiome."5.91Modifying effects of 2,4-D and Glyphosate exposures on gut-liver-adipose tissue axis of diet-induced non-alcoholic fatty liver disease in mice. ( Barbisan, LF; de Souza, JLH; Rodrigues, J; Romualdo, GR; Valente, LC, 2023)
"Glyphosate is a herbicide which is commonly used in agricultural areas."5.72Effects of exposure to glyphosate on oxidative stress, inflammation, and lung function in maize farmers, Northern Thailand. ( Khacha-Ananda, S; Pothirat, C; Sapbamrer, R; Sidthilaw, S; Wunnapuk, K, 2022)
"We aimed to assess whether lifetime exposure to glyphosate and its degradation product, aminomethylphosphonic acid (AMPA), is associated with elevated liver transaminases and metabolic syndrome among young adults."4.31Association of Lifetime Exposure to Glyphosate and Aminomethylphosphonic Acid (AMPA) with Liver Inflammation and Metabolic Syndrome at Young Adulthood: Findings from the CHAMACOS Study. ( Bradman, A; Eskenazi, B; Gunier, RB; Harley, KG; Holland, N; Kogut, K; Limbach, C; Mendez, X; Mills, PJ; Mora, AM; Perito, ER; Rauch, S, 2023)
"The aim of the present study was to investigate the impacts of glyphosate herbicide on the survival and proliferation of glioblastoma cells and to explore the molecular mechanisms underlying such effects."4.31Glyphosate-induced glioblastoma cell proliferation: Unraveling the interplay of oxidative, inflammatory, proliferative, and survival signaling pathways. ( Bianco, CD; Dos Santos, DC; Kviecisnki, MR; Ourique, F; Pedrosa, RC; Zamoner, A, 2023)
"Maternal exposure to glyphosate affected insulin sensitivity and caused hepatic inflammation in adult F1 mice offspring."4.12Exposure to glyphosate-based herbicide during early stages of development increases insulin sensitivity and causes liver inflammation in adult mice offspring. ( Alegre-Maller, ACP; Amorim, JPA; Balbo, SL; Bonfleur, ML; Gomes, ECZ; Teleken, JL; Vargas, R, 2022)
"Glyphosate has been detected in urine, blood and maternal milk and has been found to induce the generation of reactive oxygen species (ROS) and several cytotoxic and genotoxic effects in vitro and in animal models directly or indirectly through its metabolite, aminomethylphosphonic acid (AMPA)."2.72Pleiotropic Outcomes of Glyphosate Exposure: From Organ Damage to Effects on Inflammation, Cancer, Reproduction and Development. ( Marino, M; Meccariello, R; Mele, E; Nori, SL; Santoro, A; Viggiano, A, 2021)
"Glyphosate is an active ingredient in herbicides."1.91Adhesion Molecules in Lung Inflammation from Repeated Glyphosate Exposures. ( Aulakh, G; Kirychuk, S; Pandher, U; Schneberger, D; Sethi, RS; Singh, B; Thompson, B, 2023)
"Nonalcoholic fatty liver disease (NAFLD), which is linked to western diet (WD) intake, affects 30% of the world's population and involves the crosstalk of liver steatosis, hypertrophy/inflammation of adipose tissue and deregulation of gut microbiome."1.91Modifying effects of 2,4-D and Glyphosate exposures on gut-liver-adipose tissue axis of diet-induced non-alcoholic fatty liver disease in mice. ( Barbisan, LF; de Souza, JLH; Rodrigues, J; Romualdo, GR; Valente, LC, 2023)
"Glyphosate is a herbicide which is commonly used in agricultural areas."1.72Effects of exposure to glyphosate on oxidative stress, inflammation, and lung function in maize farmers, Northern Thailand. ( Khacha-Ananda, S; Pothirat, C; Sapbamrer, R; Sidthilaw, S; Wunnapuk, K, 2022)
"Glyphosate (Gly) is an active ingredient of herbicide, its underlying toxicity on fish is still unclear."1.62Effects of chronic glyphosate exposure on antioxdative status, metabolism and immune response in tilapia (GIFT, Oreochromis niloticus). ( Cao, L; Du, J; Gu, Z; He, Q; Jia, R; Xu, P; Yin, G; Zheng, T, 2021)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (7.14)29.6817
2010's1 (7.14)24.3611
2020's12 (85.71)2.80

Authors

AuthorsStudies
Lumme, A1
Haahtela, T1
Ounap, J1
Rytilä, P1
Obase, Y1
Helenius, M1
Remes, V1
Helenius, I1
Marino, M1
Mele, E1
Viggiano, A1
Nori, SL1
Meccariello, R1
Santoro, A1
Gomes, ECZ1
Teleken, JL1
Vargas, R1
Alegre-Maller, ACP1
Amorim, JPA1
Bonfleur, ML1
Balbo, SL1
Sidthilaw, S1
Sapbamrer, R1
Pothirat, C1
Wunnapuk, K1
Khacha-Ananda, S1
Qi, L1
Dong, YM1
Chao, H1
Zhao, P1
Ma, SL1
Li, G1
Eskenazi, B1
Gunier, RB1
Rauch, S1
Kogut, K1
Perito, ER1
Mendez, X1
Limbach, C1
Holland, N1
Bradman, A1
Harley, KG1
Mills, PJ1
Mora, AM1
Adewale, OO1
Adebisi, OA1
Ojurongbe, TA1
Adekomi, DA1
Babatunde, IO1
Adebayo, EO1
Pandher, U2
Kirychuk, S2
Schneberger, D2
Thompson, B2
Aulakh, G2
Sethi, RS2
Singh, B2
Yan, B1
Sun, Y1
Fu, K1
Zhang, Y1
Lei, L1
Men, J1
Guo, Y1
Wu, S1
Han, J1
Zhou, B1
Bianco, CD1
Ourique, F1
Dos Santos, DC1
Pedrosa, RC1
Kviecisnki, MR1
Zamoner, A1
Romualdo, GR1
Valente, LC1
de Souza, JLH1
Rodrigues, J1
Barbisan, LF1
Zheng, T1
Jia, R1
Cao, L1
Du, J1
Gu, Z1
He, Q1
Xu, P1
Yin, G1
de Souza, JS1
Laureano-Melo, R1
Herai, RH1
da Conceição, RR1
Oliveira, KC1
da Silva, IDCG1
Dias-da-Silva, MR1
Romano, RM1
Romano, MA1
Maciel, RMB1
Chiamolera, MI1
Giannocco, G1

Reviews

1 review available for glyphosate and Innate Inflammatory Response

ArticleYear
Pleiotropic Outcomes of Glyphosate Exposure: From Organ Damage to Effects on Inflammation, Cancer, Reproduction and Development.
    International journal of molecular sciences, 2021, Nov-22, Volume: 22, Issue:22

    Topics: DNA Damage; Europe; Gene Expression Regulation; Glycine; Glyphosate; Herbicides; Humans; Inflammatio

2021

Other Studies

13 other studies available for glyphosate and Innate Inflammatory Response

ArticleYear
Airway inflammation, bronchial hyperresponsiveness and asthma in elite ice hockey players.
    The European respiratory journal, 2003, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Case-Control Stud

2003
Exposure to glyphosate-based herbicide during early stages of development increases insulin sensitivity and causes liver inflammation in adult mice offspring.
    Einstein (Sao Paulo, Brazil), 2022, Volume: 20

    Topics: Animals; Female; Glucose; Glycine; Glyphosate; Herbicides; Humans; Inflammation; Insulin; Insulin Re

2022
Effects of exposure to glyphosate on oxidative stress, inflammation, and lung function in maize farmers, Northern Thailand.
    BMC public health, 2022, 07-14, Volume: 22, Issue:1

    Topics: Farmers; Glycine; Glyphosate; Herbicides; Humans; Inflammation; Lung; Oxidative Stress; Thailand; Ze

2022
Glyphosate based-herbicide disrupts energy metabolism and activates inflammatory response through oxidative stress in mice liver.
    Chemosphere, 2023, Volume: 315

    Topics: Animals; Chemical and Drug Induced Liver Injury; Energy Metabolism; Glyphosate; Herbicides; Hydrogen

2023
Association of Lifetime Exposure to Glyphosate and Aminomethylphosphonic Acid (AMPA) with Liver Inflammation and Metabolic Syndrome at Young Adulthood: Findings from the CHAMACOS Study.
    Environmental health perspectives, 2023, Volume: 131, Issue:3

    Topics: Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Case-Control Studies; C

2023
Xylopia aethiopica suppresses markers of oxidative stress, inflammation, and cell death in the brain of Wistar rats exposed to glyphosate.
    Environmental science and pollution research international, 2023, Volume: 30, Issue:21

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Brain; Cell Death; Glyphosate; Herbi

2023
Adhesion Molecules in Lung Inflammation from Repeated Glyphosate Exposures.
    International journal of environmental research and public health, 2023, 04-12, Volume: 20, Issue:8

    Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Adhesion Molecules; Glyphosate; Herbicides; Inflammation

2023
Effects of glyphosate exposure on gut-liver axis: Metabolomic and mechanistic analysis in grass carp (Ctenopharyngodon idellus).
    The Science of the total environment, 2023, Dec-01, Volume: 902

    Topics: Animals; Bile Acids and Salts; Carps; Dysbiosis; Glyphosate; Inflammation; Lipid Metabolism Disorder

2023
Glyphosate-induced glioblastoma cell proliferation: Unraveling the interplay of oxidative, inflammatory, proliferative, and survival signaling pathways.
    Environmental pollution (Barking, Essex : 1987), 2023, Dec-01, Volume: 338

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cell Proliferation; Glioblastoma; Glyphosa

2023
Modifying effects of 2,4-D and Glyphosate exposures on gut-liver-adipose tissue axis of diet-induced non-alcoholic fatty liver disease in mice.
    Ecotoxicology and environmental safety, 2023, Volume: 268

    Topics: 2,4-Dichlorophenoxyacetic Acid; Adipose Tissue; Animals; Diet, Western; Glyphosate; Herbicides; Infl

2023
Effects of chronic glyphosate exposure on antioxdative status, metabolism and immune response in tilapia (GIFT, Oreochromis niloticus).
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2021, Volume: 239

    Topics: Animals; Antioxidants; Biomarkers; Cichlids; Fish Proteins; Glycine; Glyphosate; Herbicides; Immunit

2021
Pulmonary inflammatory response from co-exposure to LPS and glyphosate.
    Environmental toxicology and pharmacology, 2021, Volume: 86

    Topics: Animals; Bronchoalveolar Lavage Fluid; Cytokines; Drug Interactions; Glycine; Glyphosate; Herbicides

2021
Maternal glyphosate-based herbicide exposure alters antioxidant-related genes in the brain and serum metabolites of male rat offspring.
    Neurotoxicology, 2019, Volume: 74

    Topics: Animals; Antioxidants; Brain Chemistry; Female; Gene Expression Regulation; Gene Regulatory Networks

2019