Page last updated: 2024-10-28

glyphosate and Necrosis

glyphosate has been researched along with Necrosis in 9 studies

glyphosate: active cpd in herbicidal formulation Roundup; inhibits EC 2.5.1.19, 5-enolpyruvylshikimate-3-phosphate synthase; structure
glyphosate : A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Glyphosate can cause tissue damage such as liver and kidney in mammals."5.91Tannin alleviates glyphosate exposure-induced apoptosis, necrosis and immune dysfunction in hepatic L8824 cell line by inhibiting ROS/PTEN/PI3K/AKT pathway. ( Chen, L; Qi, M; Tao, D; Xu, S; Yu, F; Zhang, L, 2023)
"Glyphosate can cause tissue damage such as liver and kidney in mammals."1.91Tannin alleviates glyphosate exposure-induced apoptosis, necrosis and immune dysfunction in hepatic L8824 cell line by inhibiting ROS/PTEN/PI3K/AKT pathway. ( Chen, L; Qi, M; Tao, D; Xu, S; Yu, F; Zhang, L, 2023)
"Glyphosate is an organophosphorus compound and the active ingredient in commonly used herbicides, whereas polyoxyethyleneamine (POEA) is a nonionic surfactant often coupled with glyphosate in these herbicides to increase their efficacy."1.62Glyphosate and Polyoxyethyleneamine Ingestion Leading to Renal, Hepatic, and Pulmonary Failure. ( Bigner, JA; Burney, HE; Fiester, SE; Fulcher, JW; Schammel, CMG; Teuber, JM; Ward, ME; Wheeler, JF; Wheeler, SK, 2021)
"Glyphosate has been described as an endocrine disruptor affecting the male reproductive system; however, the molecular basis of its toxicity remains to be clarified."1.39Roundup disrupts male reproductive functions by triggering calcium-mediated cell death in rat testis and Sertoli cells. ( Benedetti Parisotto, E; Cattani, D; de Liz Oliveira Cavalli, VL; Heinz Rieg, CE; Mena Barreto Silva, FR; Pessoa-Pureur, R; Pierozan, P; Wilhelm Filho, D; Zamoner, A; Zanatta, L, 2013)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's6 (66.67)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Zhang, L1
Chen, L1
Tao, D1
Yu, F1
Qi, M1
Xu, S1
Hamdaoui, L1
Naifar, M1
Rahmouni, F1
Ayadi, F1
Rebai, T1
Bigner, JA1
Fiester, SE1
Fulcher, JW1
Schammel, CMG1
Ward, ME1
Burney, HE1
Wheeler, JF1
Wheeler, SK1
Teuber, JM1
de Liz Oliveira Cavalli, VL1
Cattani, D1
Heinz Rieg, CE1
Pierozan, P1
Zanatta, L1
Benedetti Parisotto, E1
Wilhelm Filho, D1
Mena Barreto Silva, FR1
Pessoa-Pureur, R1
Zamoner, A1
Benachour, N1
Séralini, GE4
Clair, E3
Mesnage, R3
Travert, C1
Gress, S2
Then, C1
Székács, A1
Defarge, N1
Malatesta, M1
Hennequin, D1
de Vendômois, JS1
Kim, YH1
Hong, JR1
Gil, HW1
Song, HY1
Hong, SY1

Other Studies

9 other studies available for glyphosate and Necrosis

ArticleYear
Tannin alleviates glyphosate exposure-induced apoptosis, necrosis and immune dysfunction in hepatic L8824 cell line by inhibiting ROS/PTEN/PI3K/AKT pathway.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2023, Volume: 266

    Topics: Animals; Apoptosis; Cell Line; Fishes; Glyphosate; Liver; Necrosis; Phosphatidylinositol 3-Kinases;

2023
Sub-chronic exposure to Kalach 360 SL-induced damage in rats' liver and hematological system.
    Environmental science and pollution research international, 2019, Volume: 26, Issue:36

    Topics: Animals; Antioxidants; Biomarkers; Environmental Exposure; Female; Glycine; Glyphosate; Hemolysis; H

2019
Glyphosate and Polyoxyethyleneamine Ingestion Leading to Renal, Hepatic, and Pulmonary Failure.
    The American journal of forensic medicine and pathology, 2021, Sep-01, Volume: 42, Issue:3

    Topics: Acute Kidney Injury; Adult; Edema; Glycine; Glyphosate; Hemorrhage; Herbicides; Humans; Liver; Liver

2021
Roundup disrupts male reproductive functions by triggering calcium-mediated cell death in rat testis and Sertoli cells.
    Free radical biology & medicine, 2013, Volume: 65

    Topics: Animals; Blotting, Western; Calcium; Glycine; Glyphosate; Herbicides; Male; Necrosis; Oxidative Stre

2013
Glyphosate formulations induce apoptosis and necrosis in human umbilical, embryonic, and placental cells.
    Chemical research in toxicology, 2009, Volume: 22, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Apoptosis; Caspase 3; Caspase 7; Cell Line

2009
A glyphosate-based herbicide induces necrosis and apoptosis in mature rat testicular cells in vitro, and testosterone decrease at lower levels.
    Toxicology in vitro : an international journal published in association with BIBRA, 2012, Volume: 26, Issue:2

    Topics: 3-Hydroxysteroid Dehydrogenases; Adenylate Kinase; Animals; Apoptosis; Aromatase; Caspase 3; Caspase

2012
Cytotoxicity on human cells of Cry1Ab and Cry1Ac Bt insecticidal toxins alone or with a glyphosate-based herbicide.
    Journal of applied toxicology : JAT, 2013, Volume: 33, Issue:7

    Topics: Adenylate Kinase; Apoptosis; Bacillus thuringiensis Toxins; Bacterial Proteins; Biomarkers; Caspase

2013
Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012, Volume: 50, Issue:11

    Topics: Animals; Carcinogens; Dose-Response Relationship, Drug; Endocrine Disruptors; Female; Glycine; Glyph

2012
Mixtures of glyphosate and surfactant TN20 accelerate cell death via mitochondrial damage-induced apoptosis and necrosis.
    Toxicology in vitro : an international journal published in association with BIBRA, 2013, Volume: 27, Issue:1

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspases; Cell Line; Cytochromes c; Fats; Glycine; G

2013