Page last updated: 2024-09-28

Epiphyses, Slipped

A complete or partial separation of the EPIPHYSES from the DIAPHYSES.

Synonyms(2)

Synonym
Epiphyses, Slipped
Epiphysiolysis

Research Excerpts

Research

Studies (111)

TimeframeStudies, This Condition (%)All Conditions %
pre-199084 (75.68)23.3326
1990's6 (5.41)12.5806
2000's18 (16.22)18.1394
2010's3 (2.70)28.8240
2020's0 (0.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
alpha-hydroxyglutarate0low10
lactic acid0low10
phenytoin0low10
aspirin0low10
azathioprine0low20
benserazide0low10
dantrolene0low10
glyphosate0low10
halothane0low10
phenobarbital0low10
propofol0low10
sevoflurane0low10
succinylcholine0low10
hydroxyproline0low20
thyroxine0low50
prednisone0low30
androsterone0low10
etiocholanolone0low10
dehydroepiandrosterone0low20
triiodothyronine0low10
cyanides0low10
methyltestosterone0low10
methandrostenolone0low20
hydrazine0low10
fusarium0low10
dehydroepiandrosterone sulfate0low10
durapatite0low10
molybdenum0low10
technetium0low80
titanium0low20
calcium sulfate0low10
trolamine salicylate0low260
diacerein0low10
fluorides0low10
remifentanil0low10
iopamidol0low10
organophosphonates0low10
cortisone0low10
fibrin0low10
pyrophosphate0low20
leuprolide0low10
cystine0low10
17-ketosteroids0low70
cholecalciferol0low20
lead0low10
phosphorus0low10
strontium radioisotopes0low20
selenium0low10
radium0low10
gadolinium dtpa0low10
technetium tc 99m diphosphonate0low40
vendex0low20
technetium tc 99m sestamibi0low10
piperidines0low10
ascorbic acid0low30
technetium tc 99m sulfur colloid0low10
technetium tc 99m medronate0low20
exudates0low10
alcian blue0low10
leptin0low10

Protein Targets (454)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Methylcytosine dioxygenase TET20112
Chain A, retinol dehydratase0101
acetylcholinesterase4004
RAR-related orphan receptor gamma120012
TDP1 protein120012
GLI family zinc finger 3100010
AR protein160016
estrogen receptor 2 (ER beta)7007
progesterone receptor8008
retinoic acid nuclear receptor alpha variant 1120012
retinoid X nuclear receptor alpha7007
estrogen-related nuclear receptor alpha140014
pregnane X nuclear receptor120012
estrogen nuclear receptor alpha180018
v-jun sarcoma virus 17 oncogene homolog (avian)9009
histone acetyltransferase KAT2A isoform 11001
Gamma-aminobutyric acid receptor subunit pi4329
Voltage-dependent calcium channel gamma-2 subunit4004
Sex hormone-binding globulin0055
Corticosteroid-binding globulin0404
Glucose-6-phosphate 1-dehydrogenase0303
Androgen receptor0303
Gamma-aminobutyric acid receptor subunit beta-14329
Gamma-aminobutyric acid receptor subunit delta4329
Gamma-aminobutyric acid receptor subunit gamma-24329
Glutamate receptor 24004
Gamma-aminobutyric acid receptor subunit alpha-54329
Gamma-aminobutyric acid receptor subunit alpha-34329
Gamma-aminobutyric acid receptor subunit gamma-14329
Gamma-aminobutyric acid receptor subunit alpha-24329
Gamma-aminobutyric acid receptor subunit alpha-44329
Gamma-aminobutyric acid receptor subunit gamma-34329
Gamma-aminobutyric acid receptor subunit alpha-64329
Solute carrier organic anion transporter family member 1A10102
Gamma-aminobutyric acid receptor subunit alpha-144210
Gamma-aminobutyric acid receptor subunit beta-34329
Gamma-aminobutyric acid receptor subunit beta-24329
TAR DNA-binding protein 434004
G-protein coupled bile acid receptor 10044
GABA theta subunit4329
Gamma-aminobutyric acid receptor subunit epsilon4329
Chain A, Hyaluronidase, phage associated0101
thioredoxin glutathione reductase4004
cytochrome P450 family 3 subfamily A polypeptide 49009
glucocorticoid receptor [Homo sapiens]110011
vitamin D (1,25- dihydroxyvitamin D3) receptor100010
IDH14004
euchromatic histone-lysine N-methyltransferase 2120012
chromobox protein homolog 16006
nuclear factor erythroid 2-related factor 2 isoform 23003
thyroid hormone receptor beta isoform 2100010
nuclear factor erythroid 2-related factor 2 isoform 1130013
lethal(3)malignant brain tumor-like protein 1 isoform I1001
geminin100010
lethal factor (plasmid)2002
lamin isoform A-delta109009
Polyphenol oxidase 20101
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0011
Spike glycoprotein3003
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE2002
Chain A, TYROSYL-DNA PHOSPHODIESTERASE3003
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein5005
Chain B, HADH2 protein5005
Chain A, 2-oxoglutarate Oxygenase2002
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 83003
thioredoxin reductase8008
GLS protein5005
aldehyde dehydrogenase 1 family, member A18008
thyroid stimulating hormone receptor2002
hypothetical protein, conserved1001
EWS/FLI fusion protein4004
cytochrome P450 2D64004
glucocerebrosidase3003
peroxisome proliferator-activated receptor delta9009
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
Bloom syndrome protein isoform 14004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
DNA polymerase iota isoform a (long)4004
DNA polymerase kappa isoform 14004
muscarinic acetylcholine receptor M15005
Prostaglandin-H2 D-isomerase0101
ATP-binding cassette sub-family C member 30404
Multidrug resistance-associated protein 40506
Solute carrier family 22 member 60101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Bile salt export pump0909
Epidermal growth factor receptor0101
Carbonic anhydrase 10606
Carbonic anhydrase 20606
Fatty acid-binding protein, liver0101
Integrin beta-32103
Myeloperoxidase0101
Prostaglandin G/H synthase 10101
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb2103
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10303
Adenosine receptor A10101
Adenosine receptor A2a0101
Substance-P receptor0101
Prostaglandin G/H synthase 20202
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma5005
Ras-related protein Rab-2A0011
Prostaglandin G/H synthase 20101
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Canalicular multispecific organic anion transporter 10404
Sigma non-opioid intracellular receptor 10112
Sigma non-opioid intracellular receptor 10011
Chain A, Ferritin light chain4004
phosphopantetheinyl transferase2002
SMAD family member 24004
ATAD5 protein, partial1001
Fumarate hydratase1001
SMAD family member 34004
Microtubule-associated protein tau6006
nuclear receptor subfamily 1, group I, member 35005
farnesoid X nuclear receptor6006
G4004
polyprotein1001
P531001
peroxisome proliferator activated receptor gamma7007
arylsulfatase A3003
aryl hydrocarbon receptor4004
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a9009
thyroid stimulating hormone receptor3003
activating transcription factor 62002
Histone H2A.x4004
peripheral myelin protein 22 isoform 13003
hemoglobin subunit beta1001
cellular tumor antigen p53 isoform a3003
heat shock protein beta-14004
peripheral myelin protein 224004
survival motor neuron protein isoform d4004
cytochrome P450 3A4 isoform 14004
M-phase phosphoprotein 83003
muscleblind-like protein 1 isoform 13003
Bile salt export pump0101
Interferon beta5005
HLA class I histocompatibility antigen, B alpha chain 4004
Cellular tumor antigen p539009
Inositol hexakisphosphate kinase 14004
ATPase family AAA domain-containing protein 52002
Ataxin-22002
Protein-arginine deiminase type-40101
cytochrome P450 2C9, partial4004
regulator of G-protein signaling 43003
vitamin D3 receptor isoform VDRA5005
serine/threonine-protein kinase mTOR isoform 11001
Zinc finger protein mex-50011
POsterior Segregation0011
Genome polyprotein0101
Replicase polyprotein 1ab0101
D(1A) dopamine receptor1001
Hexokinase-20101
ATP-dependent phosphofructokinase1001
Chain A, Vitamin D Nuclear Receptor0011
Chain A, Beta-lactamase2002
Vitamin D3 receptor0011
USP1 protein, partial7007
PPM1D protein1001
mitogen-activated protein kinase 12002
nuclear receptor ROR-gamma isoform 15005
Vitamin D-binding protein0011
Cytochrome P450 1A20001
Cytochrome P450 3A40315
Androgen receptor0202
Cytochrome P450 2D60101
Vitamin D3 receptor0238
Cytochrome P450 2C9 0203
Vitamin D3 receptor0113
Retinoic acid receptor RXR-alpha0033
Cytochrome P450 2C190101
Kappa-type opioid receptor0213
Vitamin D3 receptor0022
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0011
Vitamin D3 receptor0112
Transporter0101
Vitamin D3 receptor A0022
Chain A, Cruzipain2002
Luciferase1001
15-lipoxygenase, partial1001
thyroid hormone receptor beta isoform a5005
60 kDa chaperonin0101
60 kDa heat shock protein, mitochondrial0101
Glycine receptor subunit alpha-10011
10 kDa heat shock protein, mitochondrial0101
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
endonuclease IV2002
dopamine D1 receptor1001
pregnane X receptor3003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a4004
atrial natriuretic peptide receptor 1 precursor2002
flap endonuclease 13003
Glucocorticoid receptor0617
Glycine receptor subunit alpha-10606
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Potassium voltage-gated channel subfamily A member 10011
Multidrug and toxin extrusion protein 10101
Carbonic anhydrase 40202
Carbonic anhydrase0303
Carbonic anhydrase 150202
hypoxia-inducible factor 1 alpha subunit1001
Beta-glucuronidase0101
Beta-glucuronidase0101
Alpha-synuclein1001
Glucose-6-phosphate 1-dehydrogenase 0101
NPC1-like intracellular cholesterol transporter 10011
Solute carrier organic anion transporter family member 1A40104
Solute carrier organic anion transporter family member 1A50003
Steryl-sulfatase0001
Multidrug resistance-associated protein 1 0001
Solute carrier organic anion transporter family member 1A20003
Solute carrier organic anion transporter family member 1A30003
ATP-binding cassette sub-family C member 110001
Solute carrier organic anion transporter family member 1B30002
Solute carrier family 22 member 110001
Solute carrier organic anion transporter family member 1A10001
Solute carrier organic anion transporter family member 1B20001
Solute carrier organic anion transporter family member 1B10003
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
Chain A, JmjC domain-containing histone demethylation protein 3A1001
WRN1001
90-kda heat shock protein beta HSP90 beta, partial0101
isocitrate dehydrogenase 1, partial1001
nonstructural protein 11001
67.9K protein1001
bromodomain adjacent to zinc finger domain 2B1001
pyruvate kinase1001
caspase 7, apoptosis-related cysteine peptidase0011
huntingtin isoform 21001
pyruvate kinase PKM isoform a1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
caspase-3 isoform a preproprotein0011
serine/threonine-protein kinase PLK12002
eyes absent homolog 2 isoform a1001
heat shock protein HSP 90-alpha isoform 20101
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 12002
Rev0101
endoribonuclease toxin MazF0011
Female germline-specific tumor suppressor gld-10101
Transthyretin0204
Endothelin receptor type B1001
Endothelin-1 receptor1001
Disintegrin and metalloproteinase domain-containing protein 171001
Fatty-acid amide hydrolase 10202
N-acylethanolamine-hydrolyzing acid amidase0101
C-terminal-binding protein 11001
Monoglyceride lipase0101
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)0101
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)0101
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)0101
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)0101
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)0101
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)0101
ClpP1001
Smad31001
Testosterone 17-beta-dehydrogenase 30101
Guanine nucleotide-binding protein G1001
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase0101
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase0101
Glutamine synthetase 0101
Cytochrome P450 71B10102
Glutamine synthetase 0101
2-dehydro-3-deoxyphosphooctonate aldolase0101
Albumin0101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Neutral amino acid transporter A0101
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0101
Proton-coupled amino acid transporter 10101
Amino acid transporter0101
nuclear receptor subfamily 1, group I, member 21001
Gonadotropin-releasing hormone receptor0101
Gonadotropin-releasing hormone receptor0202
transcriptional regulator ERG isoform 32002
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
Opioid receptor, delta 1b 0101
Solute carrier family 22 member 1 0101
Acetylcholinesterase0101
Opioid receptor homologue0101
ATP-dependent translocase ABCB10101
Acyl-CoA desaturase 10101
ATP-dependent translocase ABCB10101
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M50101
Alpha-2A adrenergic receptor0011
Muscarinic acetylcholine receptor M20101
Translocator protein0011
Histidine decarboxylase0011
ATP-dependent translocase ABCB10101
Proteinase-activated receptor 10112
Sodium-dependent serotonin transporter0101
Delta-type opioid receptor0102
Delta-type opioid receptor0214
Kappa-type opioid receptor0214
Mu-type opioid receptor0317
Kappa-type opioid receptor0214
Mu-type opioid receptor0214
UDP-glucuronosyltransferase 1A30001
Delta-type opioid receptor0214
Kappa-type opioid receptor0214
Mu-type opioid receptor0215
Nociceptin receptor0101
5-hydroxytryptamine receptor 70101
Mu-type opioid receptor0101
Mu-type opioid receptor0202
Potassium voltage-gated channel subfamily H member 20303
Beta-2 adrenergic receptor0101
Mas-related G-protein coupled receptor member X20011
Mu-type opioid receptor0101
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 2 subunit alpha0202
Sodium channel protein type 3 subunit alpha0202
Gamma-aminobutyric acid 0101
cytochrome P450 2C9 precursor1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Dihydrofolate reductase 0101
Sodium channel protein type 2 subunit alpha0101
Gamma-aminobutyric acid receptor subunit alpha-10314
Aldo-keto reductase family 1 member B10101
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit beta-10213
Gamma-aminobutyric acid receptor subunit gamma-20314
5-hydroxytryptamine receptor 1A0101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit beta-30314
Gamma-aminobutyric acid receptor subunit alpha-50213
Gamma-aminobutyric acid receptor subunit alpha-30213
Sodium channel protein type 4 subunit alpha0102
Histamine H2 receptor1001
Gamma-aminobutyric acid receptor subunit alpha-20213
Gamma-aminobutyric acid receptor subunit beta-20213
Gamma-aminobutyric acid receptor subunit alpha-40213
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit epsilon0202
Inositol monophosphatase 11001
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Sodium channel protein type 5 subunit alpha0101
Sodium channel protein type 9 subunit alpha0101
Gamma-aminobutyric acid receptor subunit alpha-60213
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit gamma-10202
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit gamma-30202
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit theta0202
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
caspase 7, apoptosis-related cysteine protease1001
caspase-31001
D(1A) dopamine receptor2002
Fatty-acid amide hydrolase 10101
UDP-glucuronosyltransferase 1A90001
5-hydroxytryptamine receptor 40202
Aldo-keto reductase family 1 member B10202
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Polyunsaturated fatty acid lipoxygenase ALOX150101
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
Sodium-dependent noradrenaline transporter 0202
Sodium- and chloride-dependent GABA transporter 10101
5-hydroxytryptamine receptor 2C0202
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
5-hydroxytryptamine receptor 2B0202
Sodium- and chloride-dependent betaine transporter0101
UDP-glucuronosyltransferase 1A80001
Chain A, dATP pyrophosphohydrolase0101
Chain A, Adenylate cyclase type 50101
Chain B, Adenylate cyclase type 20101
Sigma non-opioid intracellular receptor 10112
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Acetylcholinesterase0101
Chain X, Thyroid hormone receptor beta-10022
Chain X, Thyroid hormone receptor beta-10022
apical membrane antigen 1, AMA12002
Nuclear receptor subfamily 1 group I member 20011
Rap guanine nucleotide exchange factor 31001
Thyroid hormone receptor alpha0235
Thyroid hormone receptor beta0235
Proliferating cell nuclear antigen0202
UDP-glucuronosyltransferase 1A1 0101
Peroxisome proliferator-activated receptor gamma0044
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 4C10102
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
glp-1 receptor, partial1001
neuropeptide S receptor isoform A1001
Prothrombin0011
Thyroid hormone receptor beta0101
Adenosine receptor A10202
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 4A10001
Solute carrier organic anion transporter family member 1C10101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]