Synovial Cyst

Non-neoplastic tumor-like lesions at joints, developed from the SYNOVIAL MEMBRANE of a joint through the JOINT CAPSULE into the periarticular tissues. They are filled with SYNOVIAL FLUID with a smooth and translucent appearance. A synovial cyst can develop from any joint, but most commonly at the back of the knee, where it is known as POPLITEAL CYST.

Synonym
Synovial Cysts
Synovial Cyst

Excerpt	Reference
"Intraspinal synovial cysts are usually located in the lower lumbar spine in association with osteoarthritis of the facet joints, and they are most accurately diagnosed by using CT."	( Bjorkengren, AG; Garfin, SR; Kurz, LT; Resnick, D; Sartoris, DJ, 1987)
"Synovial cysts are near-water-density masses, often associated with a small joint effusion."	( Heiken, JP; Lee, JK; Murphy, WA; Smathers, RL; Totty, WG, 1984)
"Intraforaminal synovial cyst is a highly unusual finding."	( Do, L; Dufour, H; Figarella-Branger, D; Fuentes, S; Grisoli, F; Métellus, P, 2002)
"Synovial cysts are well known in rheumatoid arthritis (RA), and most common in the popliteal fossa."	( Li, Z; Mao, X; Wang, J; Zhang, J, 2018)
"Synovial cysts are most commonly found in the lumbar spine and are associated with low back pain and radiculopathy."	( Espinosa, JA; Michael, AP; Nordmann, NJ, 2019)
"The diagnosis of synovial cysts are increasing in frequency due to their ease of identification with computed tomography and MRI."	( Espinosa, JA; Michael, AP; Nordmann, NJ, 2019)

Excerpt	Reference
"Spinal synovial cysts have not been described in spondyloarthropathies (SpA)."	( Finckh, A; Gerster, J; So, AK, 2003)

Excerpt	Reference
"This is the first report of a synovial cyst hematoma due to anticoagulation therapy."	( Garges, KJ; Nourbakhsh, A, 2007)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	157 (59.02)	23.3326
1990's	57 (21.43)	12.5806
2000's	32 (12.03)	18.1394
2010's	19 (7.14)	28.8240
2020's	1 (0.38)	9.53

Drug	Relationship Strength	Studies	Trials
salicylic acid	low	1	0
lactic acid	low	1	0
phenol	low	1	0
uric acid	low	2	0
urea	low	1	0
1-anilino-8-naphthalenesulfonate	low	1	0
diatrizoic acid	low	1	0
aspirin	low	1	0
bupivacaine	low	2	0
metrizoate	low	1	0
pentetic acid	low	5	0
glyphosate	low	1	0
guaifenesin	low	5	0
lidocaine	low	2	0
ifosfamide	low	1	0
iodixanol	low	1	0
ketoconazole	low	1	0
khellin	low	2	0
succinylcholine	low	1	0
thiotepa	low	1	0
hydrocortisone acetate	low	1	0
prednisolone	low	6	0
hydroxyproline	low	1	0
prednisolone acetate	low	1	0
penicillamine	low	1	0
prednisone	low	3	0
paramethasone	low	1	0
methylprednisolone acetate	low	2	0
methylene blue	low	1	0
colchicine	low	2	0
triamcinolone acetonide	low	5	0
methylprednisolone	medium	10	2
diatrizoate meglumine	low	2	0
meglumine	low	1	0
betamethasone	low	5	0
glycopyrrolate	low	1	0
durapatite	low	2	0
triamcinolone hexacetonide	low	1	0
technetium	low	8	0
chromium	low	1	0
gadolinium	low	8	0
gold	low	1	0
ytterbium	low	1	0
yttrium	low	1	0
calcium pyrophosphate	low	2	0
trolamine salicylate	medium	26	1
iodine	low	1	0
triamcinolone	low	11	0
transferrin	low	1	0
itraconazole	low	1	0
cortivazol	low	2	0
fluorodeoxyglucose f18	low	2	0
fibrinogen	low	2	0
yttrium radioisotopes	low	3	0
methotrexate	low	1	0
atropine	low	1	0
cortisone	low	1	0
fibrin	low	1	0
inositol 3-phosphate	low	1	0
griseofulvin	low	1	0
metrizamide	low	1	0
picibanil	low	1	0
pyrophosphate	low	1	0
indigo carmine	low	1	0
sulfur	low	2	0
heroin	low	1	0
gadolinium dtpa	low	4	0
yttrium silicate	low	1	0
struvite	low	1	0
sodium tetradecyl sulfate	low	1	0
salicylates	low	1	0
dicumarol	low	1	0
mobic	low	1	0
warfarin	low	1	0
technetium tc 99m sulfur colloid	low	3	0
hyaluronoglucosaminidase	medium	7	2
technetium tc 99m medronate	low	4	0

Protein Targets (663)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	2	0	0	2
thioredoxin reductase	12	0	0	12
USP1 protein, partial	8	0	0	8
TDP1 protein	16	0	0	16
vitamin D3 receptor isoform VDRA	6	0	0	6
importin subunit beta-1 isoform 1	7	0	0	7
flap endonuclease 1	8	0	0	8
serine/threonine-protein kinase PLK1	2	0	0	2
snurportin-1	7	0	0	7
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
GTP-binding nuclear protein Ran isoform 1	6	0	0	6
DNA polymerase eta isoform 1	3	0	0	3
DNA polymerase iota isoform a (long)	7	0	0	7
urokinase-type plasminogen activator precursor	6	0	0	6
plasminogen precursor	6	0	0	6
urokinase plasminogen activator surface receptor precursor	6	0	0	6
geminin	20	0	0	20
DNA polymerase kappa isoform 1	3	0	0	3
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	2	0	2
Transthyretin	0	0	2	4
Fatty acid-binding protein, intestinal	0	2	1	3
Fatty acid-binding protein, adipocyte	0	1	1	2
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	1	1	2
Cyclin-dependent kinase 2	0	1	2	3
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	2	0	0	2
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
RAR-related orphan receptor gamma	20	0	0	20
ATAD5 protein, partial	9	0	0	9
GLS protein	5	0	0	5
Microtubule-associated protein tau	5	0	0	5
Smad3	5	0	0	5
aldehyde dehydrogenase 1 family, member A1	14	0	0	14
thyroid stimulating hormone receptor	7	0	0	7
nuclear receptor subfamily 1, group I, member 3	15	0	0	15
progesterone receptor	16	0	0	16
EWS/FLI fusion protein	7	0	0	7
retinoic acid nuclear receptor alpha variant 1	18	0	0	18
retinoid X nuclear receptor alpha	18	0	0	18
estrogen-related nuclear receptor alpha	23	0	0	23
estrogen nuclear receptor alpha	31	0	0	31
peroxisome proliferator activated receptor gamma	12	0	0	12
aryl hydrocarbon receptor	11	0	0	11
chromobox protein homolog 1	12	0	0	12
thyroid hormone receptor beta isoform 2	16	0	0	16
peripheral myelin protein 22	7	0	0	7
cytochrome P450 3A4 isoform 1	10	0	0	10
Gamma-aminobutyric acid receptor subunit pi	10	0	0	10
ATP-binding cassette sub-family C member 3	0	16	0	16
Multidrug resistance-associated protein 4	0	16	0	17
Solute carrier family 22 member 6	0	3	0	3
Carbonic anhydrase 12	0	3	0	3
UDP-glucuronosyltransferase 1A9	0	1	0	3
Bile salt export pump	0	5	0	5
Voltage-dependent calcium channel gamma-2 subunit	10	0	0	10
Bile salt export pump	0	24	0	24
Cytochrome P450 2B1	0	1	0	2
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	10	0	10
Carbonic anhydrase 2	0	10	1	11
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	2	1	4
Cytochrome P450 1A2	0	2	0	3
Prostaglandin G/H synthase 1	0	3	0	3
Carbonic anhydrase 3	0	3	0	3
Cytochrome P450 3A4	0	6	0	7
Cytochrome P450 2D6	0	3	0	3
Cytochrome P450 2C9	0	8	0	9
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	10	0	0	10
Sulfotransferase 1A1	0	0	0	2
Gamma-aminobutyric acid receptor subunit delta	10	0	0	10
Gamma-aminobutyric acid receptor subunit gamma-2	10	0	0	10
UDP-glucuronosyltransferase 1-6	0	2	0	3
Glutamate receptor 2	10	0	0	10
Gamma-aminobutyric acid receptor subunit alpha-5	10	0	0	10
Gamma-aminobutyric acid receptor subunit alpha-3	10	0	0	10
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	3	0	4
Carbonic anhydrase 4	0	4	0	4
Prostaglandin G/H synthase 1	0	6	0	6
Carbonic anhydrase 6	0	4	0	4
Gamma-aminobutyric acid receptor subunit gamma-1	10	0	0	10
Gamma-aminobutyric acid receptor subunit alpha-2	10	0	0	10
Gamma-aminobutyric acid receptor subunit alpha-4	10	0	0	10
Gamma-aminobutyric acid receptor subunit gamma-3	10	0	0	10
Gamma-aminobutyric acid receptor subunit alpha-6	10	0	0	10
Carbonic anhydrase 5A, mitochondrial	0	3	0	3
Prostaglandin G/H synthase 2	0	6	0	7
Carbonic anhydrase 7	0	3	0	3
Nuclear receptor ROR-gamma	5	0	0	5
Cytochrome P450 2J2	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	10	1	0	11
Gamma-aminobutyric acid receptor subunit beta-3	10	0	0	10
Gamma-aminobutyric acid receptor subunit beta-2	10	0	0	10
Carbonic anhydrase 9	0	4	0	4
GABA theta subunit	10	0	0	10
Canalicular multispecific organic anion transporter 1	0	15	0	15
Carbonic anhydrase 15	0	4	0	4
Carbonic anhydrase 13	0	3	0	3
Gamma-aminobutyric acid receptor subunit epsilon	10	0	0	10
Carbonic anhydrase 14	0	3	0	3
Carbonic anhydrase 5B, mitochondrial	0	3	0	3
toxin B	0	0	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	10	0	0	10
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	9	0	0	9
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, HADH2 protein	8	0	0	8
Chain B, HADH2 protein	8	0	0	8
Chain A, 2-oxoglutarate Oxygenase	9	0	0	9
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	3	0	0	3
AR protein	28	0	0	28
hypothetical protein, conserved	2	0	0	2
cytochrome P450 family 3 subfamily A polypeptide 4	15	0	0	15
glucocorticoid receptor [Homo sapiens]	23	0	0	23
cytochrome P450 2D6	11	0	0	11
glucocerebrosidase	3	0	0	3
peroxisome proliferator-activated receptor delta	14	0	0	14
Rac1 protein	0	0	1	1
IDH1	13	0	0	13
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
euchromatic histone-lysine N-methyltransferase 2	16	0	0	16
Bloom syndrome protein isoform 1	5	0	0	5
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
muscarinic acetylcholine receptor M1	5	0	0	5
lethal factor (plasmid)	4	0	0	4
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	3
Prostaglandin G/H synthase 2	0	2	0	2
Epidermal growth factor receptor	0	1	0	1
Fatty acid-binding protein, liver	0	3	0	3
Integrin beta-3	4	1	0	5
Myeloperoxidase	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	4	1	0	5
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	0	2	0	2
Adenosine receptor A2a	0	2	0	2
Substance-P receptor	0	1	0	1
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	2	0	2
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	0	1	1
Sigma non-opioid intracellular receptor 1	0	0	1	1
GLI family zinc finger 3	20	0	0	20
pregnane X nuclear receptor	18	0	0	18
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	3	0	0	3
short transient receptor potential channel 6 isoform 1	0	0	1	1
Solute carrier family 22 member 1	0	3	0	3
5-hydroxytryptamine receptor 4	0	2	0	2
Muscarinic acetylcholine receptor M2	0	6	1	10
Muscarinic acetylcholine receptor M4	0	3	1	6
Muscarinic acetylcholine receptor M1	0	2	1	5
Muscarinic acetylcholine receptor M3	0	2	1	5
Muscarinic acetylcholine receptor M4	0	2	1	5
Muscarinic acetylcholine receptor M5	0	2	1	5
Muscarinic acetylcholine receptor M5	0	3	1	6
Muscarinic acetylcholine receptor M2	0	2	1	6
Muscarinic acetylcholine receptor M1	0	3	1	7
Muscarinic acetylcholine receptor M1	0	0	0	1
Muscarinic acetylcholine receptor M3	0	4	1	7
Alpha-1D adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Muscarinic acetylcholine receptor M4	0	1	0	1
Histamine H2 receptor	4	0	0	5
5-hydroxytryptamine receptor 7	0	1	0	1
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	1	1	2
pregnane X receptor	5	0	0	5
farnesoid X nuclear receptor	12	0	0	12
vitamin D (1,25- dihydroxyvitamin D3) receptor	12	0	0	12
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	17	0	0	17
nuclear receptor subfamily 1, group I, member 2	8	0	0	8
thyroid hormone receptor beta isoform a	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 2	13	0	0	13
galanin receptor type 3	0	1	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	17	0	0	17
Glucocorticoid receptor	0	14	2	21
Glycine receptor subunit alpha-1	0	14	0	14
Glycine receptor subunit beta	0	14	0	14
Glycine receptor subunit alpha-2	0	14	0	14
Glycine receptor subunit alpha-3	0	14	0	14
ORF73	0	0	1	1
Potassium channel subfamily K member 3	0	2	0	2
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	1	2
Potassium channel subfamily K member 9	0	1	0	1
Chain A, Beta-lactamase	8	0	0	8
Chain A, Ferritin light chain	4	0	0	4
Luciferase	10	0	0	10
endonuclease IV	4	0	0	4
PAX8	0	0	0	1
hypoxia-inducible factor 1 alpha subunit	11	0	0	11
Fumarate hydratase	4	0	0	4
PPM1D protein	5	0	0	5
Thrombopoietin	1	0	0	1
estrogen receptor 2 (ER beta)	12	0	0	12
polyprotein	4	0	0	4
67.9K protein	3	0	0	3
activating transcription factor 6	6	0	0	6
v-jun sarcoma virus 17 oncogene homolog (avian)	12	0	0	12
cytochrome P450 2D6 isoform 1	2	0	0	2
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cellular tumor antigen p53 isoform a	5	0	0	5
cytochrome P450 2C19 precursor	4	0	0	4
cytochrome P450 2C9 precursor	3	0	0	3
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
ras-related protein Rab-9A	1	0	0	1
steroidogenic factor 1	0	1	0	1
muscleblind-like protein 1 isoform 1	6	0	0	6
caspase-1 isoform alpha precursor	3	0	0	3
lamin isoform A-delta10	12	0	0	12
neuropeptide S receptor isoform A	2	0	0	2
Solute carrier family 22 member 3	0	1	0	1
Interferon beta	12	0	0	12
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	1
Tubulin beta-4A chain	0	2	2	5
Cellular tumor antigen p53	18	0	0	18
ATP-dependent translocase ABCB1	0	3	0	3
Tubulin beta chain	0	2	2	5
ATP-dependent translocase ABCB1	0	3	0	4
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	0	0	1
ATPase family AAA domain-containing protein 5	12	0	0	12
Ataxin-2	12	0	0	12
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
ATP-dependent phosphofructokinase	6	0	0	6
dopamine D1 receptor	2	0	0	2
regulator of G-protein signaling 4	2	0	0	2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	8	0	0	8
peripheral myelin protein 22 isoform 1	4	0	0	4
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
heat shock protein beta-1	9	0	0	9
survival motor neuron protein isoform d	9	0	0	9
M-phase phosphoprotein 8	3	0	0	3
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	3	0	3
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
TAR DNA-binding protein 43	6	0	0	6
Multidrug and toxin extrusion protein 1	0	3	0	3
Hsf1 protein	0	0	2	2
Aldo-keto reductase family 1 member B10	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Dihydrofolate reductase	0	3	0	4
Cytochrome c oxidase subunit 2	0	1	0	1
Albumin	0	2	2	4
Interleukin-8	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	1	0	2
UDP-glucuronosyltransferase 1A4	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
UDP-glucuronosyltransferase 1A3	0	0	0	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Solute carrier family 22 member 6	0	2	0	4
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
G	7	0	0	7
Histone H2A.x	8	0	0	8
potassium voltage-gated channel subfamily H member 2 isoform d	4	0	0	4
HLA class I histocompatibility antigen, B alpha chain	7	0	0	7
NAD	0	1	0	1
Cholinesterase	0	1	0	1
Urease	0	1	0	1
NAD	0	1	0	2
Mitogen-activated protein kinase 1	0	1	0	1
ATP phosphoribosyltransferase	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Integrase	0	1	0	1
Inositol hexakisphosphate kinase 1	7	0	0	7
G-protein coupled receptor 35	0	1	1	2
cytochrome P450 2C9, partial	7	0	0	7
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Glutamine synthetase	0	1	0	1
Cytochrome P450 71B1	0	1	0	2
Glutamine synthetase	0	1	0	1
2-dehydro-3-deoxyphosphooctonate aldolase	0	1	0	1
Chain A, Cruzipain	2	0	0	2
SMAD family member 2	7	0	0	7
SMAD family member 3	7	0	0	7
caspase 7, apoptosis-related cysteine protease	4	0	0	4
caspase-3	4	0	0	4
thyroid stimulating hormone receptor	6	0	0	6
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Heme oxygenase 1	0	1	0	1
Heme oxygenase 2	0	1	0	1
Spike glycoprotein	7	0	0	7
Lanosterol 14-alpha demethylase	0	3	1	4
Rap guanine nucleotide exchange factor 3	2	0	0	2
Liver carboxylesterase 1	0	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	7	0	0	7
transcriptional regulator ERG isoform 3	3	0	0	3
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Proton-coupled amino acid transporter 1	0	1	0	1
Amino acid transporter	0	1	0	1
GALC protein	5	0	0	5
Serum paraoxonase/arylesterase 1	0	1	0	1
histone deacetylase 9 isoform 3	3	0	0	3
Carbonic anhydrase	0	2	0	2
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Estrogen receptor beta	0	1	0	2
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	2	0	2
Cytochrome P450 26A1	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Camphor 5-monooxygenase	0	0	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Chymotrypsinogen A	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	2	0	2
Epoxide hydrolase 1	0	0	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Cytochrome P450 2C11	0	1	0	1
Steroid 21-hydroxylase	0	1	0	1
Alpha-2A adrenergic receptor	0	2	0	2
Cytochrome P450 2C8	0	1	0	1
Aromatase	0	2	0	2
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Cytochrome P450 2A2	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Translocator protein	0	1	0	1
Alpha-2B adrenergic receptor	0	2	0	2
Cytochrome P450 7A1	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Estrogen receptor	0	1	0	2
Substance-K receptor	0	2	0	2
Sodium-dependent noradrenaline transporter	0	2	1	3
Thromboxane-A synthase	0	1	0	1
Histamine H2 receptor	0	2	0	2
Gonadotropin-releasing hormone receptor	0	1	1	2
Sodium-dependent serotonin transporter	0	2	0	2
Type-1 angiotensin II receptor	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Delta-type opioid receptor	0	2	0	2
Cytochrome P450 4F2	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	2	0	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	2	0	2
Sodium/bile acid cotransporter	0	1	0	1
Cytochrome P450 7A1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
glp-1 receptor, partial	3	0	0	3
mitogen-activated protein kinase 1	4	0	0	4
histone acetyltransferase KAT2A isoform 1	4	0	0	4
Cytochrome P450 2C19	0	1	0	1
Cytochrome P450 1B1	0	1	0	1
acetylcholinesterase	6	0	0	6
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
ClpP	1	0	0	1
15-lipoxygenase, partial	2	0	0	2
phosphopantetheinyl transferase	3	0	0	3
Thymidylate synthase	0	1	0	1
alpha-galactosidase	4	0	0	4
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	1	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Thymidylate synthase	0	2	0	2
5-hydroxytryptamine receptor 2C	0	1	0	2
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Glucose-6-phosphate 1-dehydrogenase	0	3	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	0	0	1
Delta-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
Caspase-7	2	0	0	2
Solute carrier organic anion transporter family member 1A3	0	0	0	1
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Solute carrier family 22 member 8	0	2	0	3
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Solute carrier organic anion transporter family member 1B3	0	0	0	1
Solute carrier family 22 member 11	0	0	0	1
Protein-arginine deiminase type-4	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	0	0	1
Chain E, Fibrin beta chain	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	4	0	0	4
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
thioredoxin glutathione reductase	3	0	0	3
isocitrate dehydrogenase 1, partial	1	0	0	1
luciferase	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
serine-protein kinase ATM isoform a	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
caspase-9 isoform alpha precursor	0	1	0	1
huntingtin isoform 2	1	0	0	1
pyruvate kinase PKM isoform a	1	0	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
Vpr	1	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glutathione reductase	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	3
Glycoprotein hormones alpha chain	1	0	0	1
Albumin	0	0	0	1
Amyloid-beta precursor protein	0	1	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Alpha-1B adrenergic receptor	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
Cruzipain	0	1	0	1
Alpha-synuclein	1	0	0	1
Alpha-1A adrenergic receptor	0	1	0	1
Inositol monophosphatase 1	2	0	0	2
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
phosphoglycerate kinase	1	0	0	1
nonstructural protein 1	3	0	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Androgen receptor	0	3	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Cystathionine gamma-lyase	0	2	0	2
Succinyl-diaminopimelate desuccinylase	0	1	0	1
arylsulfatase A	3	0	0	3
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Polyphenol oxidase 2	0	1	0	3
Endolysin	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-2	0	0	1	1
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 3	0	2	0	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
nuclear receptor ROR-gamma isoform 1	3	0	0	3
Chain A, dATP pyrophosphohydrolase	0	1	0	1
Chain A, Adenylate cyclase type 5	0	1	0	1
Chain B, Adenylate cyclase type 2	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Acetylcholinesterase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
D(1A) dopamine receptor	1	0	0	1
Acetylcholinesterase	0	1	0	1
hemoglobin subunit beta	1	0	0	1
Cytochrome P450 2B6	0	1	0	1
NFKB1 protein, partial	2	0	0	2
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, PAPAIN	1	0	0	1
putative alpha-glucosidase	1	0	0	1
pyruvate kinase	1	0	0	1
Janus kinase 2 (a protein tyrosine kinase)	0	1	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
tumor necrosis factor	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Cathepsin G	0	1	0	1
Ornithine decarboxylase	1	0	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Cyclin-dependent kinase 4	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
G1/S-specific cyclin-D1	0	1	0	1
Caspase-1	0	1	0	1
Casein kinase I isoform alpha	0	1	0	1
Casein kinase I isoform delta	0	1	0	1
Casein kinase I isoform epsilon	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Guanine deaminase	0	1	0	1
Albumin	0	0	1	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Protease	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(2)

Research Excerpts

Overview

Context

Treatment

Research

Studies (266)

Protein Targets (663)

Synovial Cyst

Synonyms(2)

Research Excerpts

Overview

Context

Treatment

Research

Studies (266)

Drugs Studied (93)

Protein Targets (663)