Niemann-Pick Disease, Type C

An autosomal recessive lipid storage disorder that is characterized by accumulation of CHOLESTEROL and SPHINGOMYELINS in cells of the VISCERA and the CENTRAL NERVOUS SYSTEM. Type C (or C1) and type D are allelic disorders caused by mutation of the NPC1 gene, which encodes a protein that mediates intracellular cholesterol transport from LYSOSOMES. Clinical signs include hepatosplenomegaly and chronic neurological symptoms. Type D is a variant in people with a Nova Scotia ancestry.

Synonym
Niemann-Pick Disease, Type C

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	53 (10.73)	18.1394
2010's	323 (65.38)	28.8240
2020's	118 (23.89)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	3	0
acetic acid	low	1	0
methane	low	1	0
choline	low	3	0
creatine	low	1	0
dimethylglycine	low	1	0
glycine	low	1	0
palmitic acid	low	1	0
phosphorylcholine	low	6	0
sarcosine	low	1	0
pk 11195	low	1	0
14,15-epoxy-5,8,11-eicosatrienoic acid	low	1	0
acetyl-dl-leucine	medium	4	2
alexidine	low	1	0
baclofen	low	1	0
chloroquine	low	1	0
chlorpromazine	low	2	0
dipyridamole	low	1	0
valproic acid	low	4	0
donepezil	low	1	0
gentamicin	low	1	0
hydroxychloroquine	low	2	0
ibuprofen	low	1	0
imipramine	low	2	0
midazolam	low	1	0
pd 98059	low	1	0
primidone	low	1	0
probucol	low	1	0
riluzole	low	1	0
stearic acid	low	1	0
vorinostat	low	6	0
dehydroepiandrosterone	low	1	0
biguanides	low	1	0
carbon tetrachloride	low	1	0
alanine	low	1	0
serine	low	1	0
aspartic acid	low	2	0
lysine	low	1	0
adenosine diphosphate	low	1	0
bromodeoxyuridine	low	2	0
levodopa	low	1	0
edetic acid	low	1	0
tyrosine	low	1	0
adenosine monophosphate	low	1	0
leucine	medium	5	2
lactose	low	1	0
asparagine	low	1	0
tryptophan	low	1	0
isoleucine	low	1	0
trehalose	low	1	0
pyrroles	low	1	0
pyrazines	low	1	0
perfluorodecalin	low	1	0
azacitidine	low	1	0
cepharanthine	low	1	0
phenylpropanolamine	low	1	0
androstenediol	low	1	0
methoxyhydroxyphenylglycol	low	1	0
d-alpha tocopherol	low	5	0
tocopherols	low	2	0
manganese	low	1	0
galactosamine	low	1	0
poloxalene	low	1	0
1-deoxynojirimycin	medium	93	5
ursodeoxycholic acid	low	1	0
pregnanolone	low	12	0
4-methoxyamphetamine	low	1	0
8-bromo cyclic adenosine monophosphate	low	1	0
glutamic acid	low	5	0
azides	low	1	0
lovastatin	low	3	0
adenosine	low	5	0
mevastatin	low	1	0
n-acetylaspartic acid	low	2	0
cholesteryl sulfate	low	2	0
25-hydroxycholesterol	low	4	0
methacycline	low	1	0
triazoles	low	2	0
fluorodeoxyglucose f18	low	3	0
cholest-5-ene-3,4-diol	low	1	0
7-ketocholesterol	low	10	0
cholestane-3,5,6-triol, (3beta, 5alpha, 6beta)-isomer	low	1	0
3,4-dihydroxyphenylglycol	low	1	0
delta-tocopherol	low	2	0
3 beta-hydroxy-delta 5-cholenic acid	low	1	0
pyrroline	low	1	0
6-ketocholestanol	low	1	0
(20s)-20-hydroxycholesterol	low	1	0
imatinib mesylate	low	1	0
naadp	low	1	0
27-hydroxycholesterol	low	1	0
ezetimibe	low	2	0
vatalanib	low	1	0
ys 64	low	1	0
(22r)-22-hydroxycholesterol	low	1	0
22s-hydroxycholesterol	low	1	0
zm 241385	low	1	0
arimoclomol	medium	2	1
3-nitrotyrosine	low	1	0
bortezomib	low	1	0
leupeptins	low	1	0
betadex	medium	60	1
ergosterol	low	2	0
arachidonic acid	low	3	0
oleic acid	low	2	0
geranylgeranyl pyrophosphate	low	1	0
gw 3965	low	1	0
t0901317	low	1	0
y 27632	low	1	0
decitabine	low	1	0
benzyloxycarbonylleucyl-leucyl-leucine aldehyde	low	1	0
cholest-5-en-3 beta,7 alpha-diol, (3beta,7beta)-isomer	low	1	0
cholestane-3,5,6-triol	low	8	0
curcumin	low	4	0
fumonisin b1	low	1	0
hydroxypropyl-gamma-cyclodextrin	low	2	0
nadp	low	1	0
thioperamide	low	1	0
cytellin	low	1	0
2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine	low	2	0
sphingosine	low	17	0
ubiquinone q2	low	1	0
bilirubin	low	3	0
dinoprostone	low	1	0
psychosine	low	1	0
8,11,14-eicosatrienoic acid	low	1	0
genistein	low	2	0
coenzyme q10	medium	4	1
sphingosine 1-phosphate	low	2	0
sirolimus	low	1	0
cysteine	low	1	0
carbocyanines	low	1	0
dolichols	low	2	0
dehydroergosterol	low	2	0
sphingosine phosphorylcholine	low	4	0
thermozymocidin	low	1	0
herboxidiene	low	1	0
sphingosyl beta-glucoside	low	1	0
cdw17 antigen	low	1	0
ganglioside, gd2	low	1	0
i(3)so3-galactosylceramide	low	1	0
19-hydroxycholesterol	low	1	0
beta-escin	low	1	0
adenosine-3',5'-cyclic phosphorothioate	low	1	0
ganaxolone	low	1	0
panobinostat	low	3	0
staurosporine	low	1	0
g(m2) ganglioside	low	4	0
u 18666a	low	14	0
g(m1) ganglioside	low	2	0
alpha-synuclein	low	1	0
acebutolol	low	1	0
24-hydroxycholesterol	medium	1	1
phytosterols	low	1	0
acid phosphatase	low	1	0
cytochrome c-t	low	1	0
cellulose	low	1	0
phosphatidylcholines	low	2	0
sphingosine kinase	low	1	0
ubiquinone	medium	3	1
ro13-9904	low	1	0
cholenic acid dimethylamide	low	1	0
ponatinib	low	1	0
4,4-difluoro-4-bora-3a,4a-diaza-s-indacene	low	2	0
glycolipids	low	11	0
piperidines	low	2	0
interleukin-8	low	1	0
ascorbic acid	low	1	0
salicylates	low	1	0
transforming growth factor beta	low	1	0
cyclin d1	low	1	0
g(m3) ganglioside	low	4	0
s 8932	low	1	0
carboxymethyl-beta-cyclodextrin	low	1	0
muramidase	low	3	0
amyloid beta-peptides	low	3	0
cyclic guanosine monophosphate-adenosine monophosphate	low	1	0
octaarginine	low	1	0
leptin	low	1	0
filipin	low	19	0

Protein Targets (1,875)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Nuclear receptor ROR-gamma	6	2	4	12
Oxysterols receptor LXR-alpha	0	6	10	16
Oxysterols receptor LXR-beta	0	6	4	10
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	15	0	0	15
glucocerebrosidase	7	0	0	7
Alpha-mannosidase	0	2	0	2
alpha-galactosidase	2	0	0	2
Trehalase	0	2	0	2
lysosomal alpha-glucosidase preproprotein	4	0	0	4
Trehalase	0	1	0	1
Maltase-glucoamylase, intestinal	0	4	0	4
Trehalase	0	2	0	2
Lysosomal acid glucosylceramidase	0	4	0	4
Alpha-galactosidase A	0	1	0	1
Alpha-glucosidase MAL62	0	1	0	1
Lactase-phlorizin hydrolase	0	2	0	2
Lysosomal alpha-glucosidase	0	4	0	4
Beta-glucosidase A	0	1	0	1
Sucrase-isomaltase, intestinal	0	2	0	2
Alpha-1B adrenergic receptor	0	8	0	8
Sucrase-isomaltase, intestinal	0	2	0	2
Alpha-1D adrenergic receptor	0	9	0	9
Beta-glucosidase	0	1	0	1
Protein-lysine 6-oxidase	0	4	0	4
Alpha-mannosidase 2	0	2	0	2
Glycogen debranching enzyme	0	2	0	2
Glycogen debranching enzyme	0	1	0	1
Alpha-glucosidase MAL32	0	4	0	4
Alpha-1A adrenergic receptor	0	9	0	9
Oligo-1,6-glucosidase IMA1	0	1	0	1
Alpha-glucosidase MAL12	0	2	0	2
Spike glycoprotein	19	2	4	25
Alpha-amylase	0	1	0	1
Trehalose synthase/amylase TreS	0	1	0	1
Lactase-phlorizin hydrolase	0	2	0	2
Neutral alpha-glucosidase AB	0	2	0	2
Ceramide glucosyltransferase	0	2	0	2
Lysosomal acid glucosylceramidase	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
Beta-glucosidase	0	1	0	1
Lysosomal alpha-glucosidase	0	2	0	2
Cytosolic beta-glucosidase	0	1	0	1
Non-lysosomal glucosylceramidase	0	2	0	2
Putative alpha-glucosidase	0	2	0	2
dopamine D1 receptor	5	0	0	5
GLS protein	11	0	0	11
regulator of G-protein signaling 4	18	0	0	18
euchromatic histone-lysine N-methyltransferase 2	36	0	0	36
DNA polymerase kappa isoform 1	12	0	0	12
histone acetyltransferase KAT2A isoform 1	10	0	0	10
Adenosine receptor A3	0	5	3	9
Adenosine receptor A1	0	3	2	8
Adenosine receptor A3	0	3	0	4
Adenosine receptor A2a	0	8	5	15
Adenosine receptor A2b	0	3	2	8
Adenosine receptor A2b	0	2	1	4
Adenosine receptor A1	0	9	5	15
Adenosine receptor A2a	0	5	3	12
Adenosine receptor A1	0	0	2	2
Mu-type opioid receptor	0	3	0	3
ATP-dependent phosphofructokinase	12	0	0	12
Cytochrome P450 3A4	0	12	2	17
Sterol O-acyltransferase 1	0	2	0	2
NPC1-like intracellular cholesterol transporter 1	0	1	9	10
TDP1 protein	36	0	0	36
cytochrome P450 family 3 subfamily A polypeptide 4	20	0	0	20
estrogen nuclear receptor alpha	43	0	0	43
peripheral myelin protein 22	24	0	0	24
Alpha-crystallin B chain	0	0	1	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	4	1	5
Cellular tumor antigen p53	28	0	0	28
Integrin beta-3	6	0	2	8
Integrin alpha-V	0	0	1	1
Glutamate receptor ionotropic, NMDA 1	0	2	1	3
Sterol regulatory element-binding protein 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	2	1	3
Glutamate receptor ionotropic, NMDA 2B	0	2	1	3
Oxysterol-binding protein 2	0	0	1	1
Ephrin type-A receptor 2	0	2	3	5
Chain A, Putative fructose-1,6-bisphosphate aldolase	5	0	0	5
Chain A, JmjC domain-containing histone demethylation protein 3A	7	0	0	7
phosphopantetheinyl transferase	17	0	0	17
bromodomain adjacent to zinc finger domain 2B	6	0	0	6
pyruvate kinase PKM isoform a	2	0	0	2
geminin	33	0	0	33
Glycoprotein hormones alpha chain	1	0	0	1
Guanine nucleotide-binding protein G	5	0	0	5
Tubulin--tyrosine ligase	0	2	0	2
5-hydroxytryptamine receptor 2C	0	6	1	7
5-hydroxytryptamine receptor 2A	0	6	1	7
5-hydroxytryptamine receptor 1A	0	9	2	11
5-hydroxytryptamine receptor 1B	0	6	1	7
5-hydroxytryptamine receptor 1D	0	2	1	3
5-hydroxytryptamine receptor 1F	0	2	1	3
5-hydroxytryptamine receptor 2B	0	6	1	7
5-hydroxytryptamine receptor 6	0	1	1	2
Sodium-dependent serotonin transporter	0	7	2	9
Sodium-dependent serotonin transporter	0	4	0	4
5-hydroxytryptamine receptor 7	0	3	1	4
5-hydroxytryptamine receptor 5A	0	1	1	2
5-hydroxytryptamine receptor 5B	0	1	1	2
5-hydroxytryptamine receptor 3A	0	1	1	2
5-hydroxytryptamine receptor 4	0	1	1	2
5-hydroxytryptamine receptor 3B	0	1	1	2
serine/threonine-protein kinase PLK1	3	0	0	3
DNA polymerase iota isoform a (long)	11	0	0	11
Rap guanine nucleotide exchange factor 3	7	0	0	7
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	3	0	3
aldehyde dehydrogenase 1 family, member A1	21	0	0	21
Trypsin	0	3	0	3
Coagulation factor VII	0	3	0	3
Tissue factor	0	5	0	5
Oxoeicosanoid receptor 1	0	1	0	1
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Tyrosine-protein kinase Lck	0	2	4	6
Tyrosine-protein kinase Fyn	0	4	4	8
Fibrinogen C domain-containing protein 1	0	1	0	1
chromobox protein homolog 1	17	0	0	17
Chain A, 2-oxoglutarate Oxygenase	10	0	0	10
Chain A, ATP-DEPENDENT DNA HELICASE Q1	4	0	0	4
acetylcholinesterase	12	0	0	12
15-lipoxygenase, partial	9	0	0	9
pregnane X receptor	9	0	0	9
RAR-related orphan receptor gamma	26	0	0	26
USP1 protein, partial	18	0	0	18
NFKB1 protein, partial	8	0	0	8
Microtubule-associated protein tau	19	0	0	19
Thrombopoietin	7	0	0	7
AR protein	41	0	0	41
glucocorticoid receptor [Homo sapiens]	33	0	0	33
retinoic acid nuclear receptor alpha variant 1	29	0	0	29
retinoid X nuclear receptor alpha	22	0	0	22
farnesoid X nuclear receptor	21	0	0	21
vitamin D (1,25- dihydroxyvitamin D3) receptor	17	0	0	17
arylsulfatase A	15	0	0	15
Bloom syndrome protein isoform 1	16	0	0	16
D(1A) dopamine receptor	9	0	0	9
thyroid hormone receptor beta isoform a	9	0	0	9
thyroid hormone receptor beta isoform 2	27	0	0	27
heat shock protein beta-1	10	0	0	10
flap endonuclease 1	10	0	0	10
survival motor neuron protein isoform d	13	0	0	13
muscarinic acetylcholine receptor M1	12	0	0	12
Histone deacetylase 3	0	10	2	15
Solute carrier family 22 member 6	0	2	0	2
Histone deacetylase 4	0	9	1	13
Histone deacetylase 1	0	13	3	19
Histone deacetylase 7	0	9	2	14
Histone deacetylase 2	0	12	3	18
Polyamine deacetylase HDAC10	0	9	1	13
Histone deacetylase 11	0	9	1	13
Ataxin-2	16	0	0	16
Histone deacetylase 8	0	11	2	16
Histone deacetylase 6	0	12	3	18
Histone deacetylase 9	0	9	1	13
Histone deacetylase 5	0	9	1	13
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
NPYLR7B	0	0	3	3
IDH1	15	0	0	15
Histone H2A.x	9	0	0	9
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
mitogen-activated protein kinase 1	9	0	0	9
nuclear receptor ROR-gamma isoform 1	14	0	0	14
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	4	4
Sodium/nucleoside cotransporter 2	0	2	0	2
Voltage-dependent calcium channel gamma-2 subunit	15	0	0	15
Purine nucleoside phosphorylase	0	1	0	1
Epidermal growth factor receptor	0	8	3	11
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	2	1	3
Insulin receptor	0	0	3	4
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	3	2	6
Platelet-derived growth factor receptor beta	0	2	3	6
Heat shock 70 kDa protein 1A	0	2	1	3
Heat shock cognate 71 kDa protein	0	0	2	2
Fibroblast growth factor receptor 1	0	1	3	6
Inosine-5'-monophosphate dehydrogenase 2	0	1	3	4
Endoplasmin	0	1	1	3
Glutamate receptor 2	15	2	1	18
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	1	1	3
Fibroblast growth factor receptor 4	0	1	1	3
Fibroblast growth factor receptor 3	0	1	1	3
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenylate kinase 2, mitochondrial	0	2	0	3
Adenylate kinase isoenzyme 1	0	2	0	3
Phosphatidylinositol 4-kinase alpha	0	4	0	5
Adenosine kinase	0	0	3	4
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	4	0	5
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	4	0	4
Phosphatidylinositol 4-kinase type 2-alpha	0	4	0	5
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	4	1	6
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-beta	0	1	1	3
2-dehydropantoate 2-reductase	0	2	2	4
Endoplasmic reticulum chaperone BiP	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	1	0	1
Mu-type opioid receptor	0	2	1	3
Delta-type opioid receptor	0	3	1	4
Kappa-type opioid receptor	0	2	1	3
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	2	2
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	2	2
P2Y purinoceptor 1	0	0	2	2
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	4	0	0	4
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
P2Y purinoceptor 11	0	0	2	2
P2Y purinoceptor 12	0	0	1	1
Sensor protein kinase WalK	0	1	0	1
P2X purinoceptor 2	0	0	1	1
Chain A, Glycogen Phosphorylase B	0	0	1	1
Chain B, Glycogen Phosphorylase B	0	0	1	1
Chain A, ADP-dependent glucokinase	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, phosphodiesterase-nucleotide pyrophosphatase	0	1	0	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain B, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
estrogen-related nuclear receptor alpha	33	0	0	33
v-jun sarcoma virus 17 oncogene homolog (avian)	10	0	0	10
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	1	1
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
L-lactate dehydrogenase A chain	0	1	1	2
Adenylate kinase isoenzyme 1	0	0	0	1
Fructose-1,6-bisphosphatase 1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	3
Fructose-1,6-bisphosphatase 1	0	1	0	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
Cytochrome P450 2C9	0	9	0	9
Proto-oncogene tyrosine-protein kinase Src	0	4	3	7
Amine oxidase [flavin-containing] B	0	3	0	3
5'-nucleotidase	0	0	0	1
Choline O-acetyltransferase	0	1	0	1
GTP:AMP phosphotransferase AK3, mitochondrial	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	5	5
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	2	2
Adenylate kinase 2, mitochondrial	0	0	3	4
Glycine--tRNA ligase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	5	5
Adenosine deaminase-like protein	0	0	0	1
Protease	0	1	1	2
Histamine H3 receptor	0	2	0	2
5'-AMP-activated protein kinase subunit gamma-3	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	4	4
5'-AMP-activated protein kinase subunit beta-1	0	0	2	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	15	0	0	15
Carbonic anhydrase 1	0	2	0	9
Carbonic anhydrase 2	0	2	0	9
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	2
Glutamate receptor ionotropic, NMDA 1	0	8	2	13
Proton-coupled amino acid transporter 1	0	8	0	9
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	0	0	2
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	14	0	0	14
Estrogen receptor	0	3	2	5
Sex hormone-binding globulin	0	0	4	4
Corticosteroid-binding globulin	0	3	0	4
Androgen receptor	0	2	0	3
Androgen receptor	0	5	0	5
Gamma-aminobutyric acid receptor subunit gamma-2	11	7	3	21
Gamma-aminobutyric acid receptor subunit alpha-5	11	7	1	19
Gamma-aminobutyric acid receptor subunit beta-3	11	7	1	19
Estrogen receptor beta	0	3	2	5
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	2	2
Chain A, SERUM ALBUMIN	0	0	2	2
Chain A, Beta-lactamase	12	0	0	12
Chain A, HADH2 protein	9	0	0	9
Chain B, HADH2 protein	9	0	0	9
Chain A, Cruzipain	8	0	0	8
thioredoxin glutathione reductase	5	0	0	5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
cellular tumor antigen p53 isoform a	8	0	0	8
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	6	0	0	6
vitamin D3 receptor isoform VDRA	10	0	0	10
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
cytochrome P450 3A4 isoform 1	11	0	0	11
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	0	0	2
caspase-1 isoform alpha precursor	4	0	0	4
lamin isoform A-delta10	22	0	0	22
Fatty-acid amide hydrolase 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	11	6	1	18
Polyunsaturated fatty acid lipoxygenase ALOX15B	8	0	0	8
Prostaglandin G/H synthase 1	0	4	0	5
60 kDa chaperonin	0	2	0	2
60 kDa heat shock protein, mitochondrial	0	2	0	2
Aromatase	0	4	0	4
Fatty acid-binding protein, adipocyte	0	5	3	8
Gamma-aminobutyric acid receptor subunit beta-1	11	6	1	18
Gamma-aminobutyric acid receptor subunit delta	11	6	1	18
Gamma-aminobutyric acid receptor subunit alpha-3	11	6	1	18
Gamma-aminobutyric acid receptor subunit gamma-1	11	6	1	18
Gamma-aminobutyric acid receptor subunit alpha-2	11	6	1	18
Gamma-aminobutyric acid receptor subunit alpha-4	11	6	1	18
Gamma-aminobutyric acid receptor subunit gamma-3	11	6	1	18
Gamma-aminobutyric acid receptor subunit alpha-6	11	6	1	18
Prostaglandin G/H synthase 2	0	5	2	10
Nuclear receptor subfamily 4 group A member 2	0	0	3	3
Histamine H2 receptor	12	2	0	14
10 kDa heat shock protein, mitochondrial	0	2	0	2
Calmodulin	0	1	1	3
Gamma-aminobutyric acid receptor subunit alpha-1	11	6	3	20
Gamma-aminobutyric acid receptor subunit beta-2	11	6	3	20
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
Prostaglandin G/H synthase 2	0	5	0	6
Solute carrier organic anion transporter family member 2A1	0	0	0	2
Fatty acid-binding protein 5	0	4	1	5
Fatty acid-binding protein 5	0	0	1	1
Thiosulfate sulfurtransferase	0	2	0	2
Lanosterol 14-alpha demethylase	0	3	0	3
60 kDa chaperonin	0	2	0	2
10 kDa chaperonin	0	2	0	2
GABA theta subunit	11	6	1	18
Gamma-aminobutyric acid receptor subunit epsilon	11	6	1	18
Solute carrier organic anion transporter family member 1B3	0	6	0	8
Cytosolic phospholipase A2 gamma	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	3	0	3
Solute carrier organic anion transporter family member 1B1	0	8	0	10
Chain A, Hyaluronidase, phage associated	0	1	0	1
GLI family zinc finger 3	25	0	0	25
nuclear factor erythroid 2-related factor 2 isoform 2	10	0	0	11
nuclear factor erythroid 2-related factor 2 isoform 1	24	0	0	24
lethal factor (plasmid)	10	0	0	10
Polyphenol oxidase 2	0	1	0	3
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	2	0	2
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	3	0	3
Alpha-2B adrenergic receptor	0	6	1	7
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Neutral amino acid transporter A	0	2	0	2
Neutral amino acid transporter B(0)	0	2	0	2
Carbonic anhydrase-like protein, putative	0	0	0	6
Amino acid transporter	0	2	0	2
Chain A, Ferritin light chain	9	0	0	9
cytochrome P450 2C19 precursor	6	0	0	6
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Glutamate receptor ionotropic, NMDA 2A	0	7	2	12
Glutamate receptor ionotropic, NMDA 2B	0	8	2	13
Glutamate receptor ionotropic, NMDA 2C	0	7	2	12
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Glutamate receptor ionotropic, NMDA 2D	0	7	2	12
Glutamate receptor ionotropic, NMDA 3B	0	7	2	12
Glutamate receptor ionotropic, NMDA 3A	0	7	2	12
interleukin 8	3	0	0	3
glp-1 receptor, partial	6	0	0	6
ATAD5 protein, partial	15	0	0	15
Fumarate hydratase	8	0	0	8
PPM1D protein	8	0	0	8
Smad3	11	0	0	11
estrogen receptor 2 (ER beta)	18	0	0	18
nuclear receptor subfamily 1, group I, member 3	17	0	0	17
progesterone receptor	16	0	0	16
pregnane X nuclear receptor	19	0	0	19
polyprotein	8	0	0	8
67.9K protein	10	0	0	10
Parkin	9	0	0	9
peroxisome proliferator-activated receptor delta	15	0	0	15
peroxisome proliferator activated receptor gamma	18	0	0	18
aryl hydrocarbon receptor	10	0	0	10
thyroid stimulating hormone receptor	12	0	0	12
activating transcription factor 6	10	0	0	10
peripheral myelin protein 22 isoform 1	8	0	0	8
hemoglobin subunit beta	2	0	0	2
huntingtin isoform 2	3	0	0	3
ras-related protein Rab-9A	5	0	0	5
serine/threonine-protein kinase mTOR isoform 1	6	0	0	6
urokinase-type plasminogen activator precursor	10	0	0	10
plasminogen precursor	10	0	0	10
urokinase plasminogen activator surface receptor precursor	10	0	0	10
Interferon beta	15	0	0	15
Integrin alpha-IIb	6	0	1	7
DNA (cytosine-5)-methyltransferase 1	0	4	0	4
D(1A) dopamine receptor	4	0	0	4
Multidrug and toxin extrusion protein 1	0	4	0	4
Histone-lysine N-methyltransferase EHMT2	0	3	0	3
ATPase family AAA domain-containing protein 5	11	0	0	11
Carbonic anhydrase 4	0	2	0	5
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase 15	0	2	0	5
thioredoxin reductase	17	0	0	17
ATP-binding cassette sub-family C member 3	0	17	0	17
Multidrug resistance-associated protein 4	0	18	0	20
Gamma-aminobutyric acid type B receptor subunit 2	0	2	2	4
Gamma-aminobutyric acid type B receptor subunit 2	0	3	0	3
Bile salt export pump	0	25	0	25
Canalicular multispecific organic anion transporter 1	0	17	0	17
Gamma-aminobutyric acid type B receptor subunit 1	0	2	2	4
Gamma-aminobutyric acid type B receptor subunit 1	0	2	0	2
Proteasome subunit beta type-11	0	2	0	3
EWS/FLI fusion protein	18	0	0	19
Calpain-9	0	1	0	1
Proteasome subunit alpha type-7	0	2	0	3
Cathepsin B	0	2	0	2
Replicase polyprotein 1ab	0	6	5	11
Replicase polyprotein 1ab	0	7	6	13
Indoleamine 2,3-dioxygenase 1	0	2	0	3
Calpain-2 catalytic subunit	0	1	0	1
Proteasome subunit beta type-1	0	3	0	5
Proteasome subunit alpha type-1	0	2	0	3
Proteasome subunit alpha type-2	0	2	0	3
Proteasome subunit alpha type-3	0	2	0	3
Proteasome subunit alpha type-4	0	2	0	3
NF-kappa-B inhibitor alpha	0	0	1	1
Proteasome subunit beta type-8	0	2	0	3
Proteasome subunit beta type-9	0	2	0	3
Proteasome subunit alpha type-5	0	2	0	3
Proteasome subunit beta type-4	0	2	0	3
Proteasome subunit beta type-6	0	2	0	3
Proteasome subunit beta type-5	0	7	0	9
Proteasome subunit beta type-10	0	2	0	3
Cathepsin K	0	1	0	1
Proteasome subunit beta type-3	0	2	0	3
Proteasome subunit beta type-2	0	3	0	5
Proteasome subunit alpha type-6	0	2	1	4
Proteasome subunit alpha-type 8	0	2	0	3
Proteasome subunit beta type-7	0	2	0	3
Gamma-secretase subunit PEN-2	0	2	1	3
Chain A, D-MALTODEXTRIN BINDING PROTEIN	0	0	1	1
Chain A, Limit Dextrinase	0	0	1	1
Chain A, Solute-binding protein	0	0	1	1
Chain A, Solute-binding protein	0	0	1	1
Chain B, SusD	0	0	1	1
Chain A, SusD	0	0	1	1
Chain A, SusD	0	0	1	1
Chain A, Alpha-hemolysin	0	0	1	1
Chain B, Alpha-hemolysin	0	0	1	1
Chain C, Alpha-hemolysin	0	0	1	1
Chain D, Alpha-hemolysin	0	0	1	1
Chain E, Alpha-hemolysin	0	0	1	1
Chain F, Alpha-hemolysin	0	0	1	1
Chain G, Alpha-hemolysin	0	0	1	1
thyroid stimulating hormone receptor	13	0	0	13
potassium voltage-gated channel subfamily H member 2 isoform d	16	0	0	16
Caspase-7	3	0	0	3
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
caspase 7, apoptosis-related cysteine protease	6	0	0	6
caspase-3	6	0	0	6
nuclear receptor subfamily 1, group I, member 2	7	0	0	7
Caspase-7	3	0	0	3
caspase-3	3	0	0	3
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Carbonic anhydrase 12	0	1	0	4
Prothrombin	0	1	1	2
Chymotrypsinogen A	0	1	0	1
Carbonic anhydrase 3	0	1	0	4
Neutrophil elastase	0	2	0	2
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Carbonic anhydrase 6	0	1	0	4
Chymase	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	4
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Carbonic anhydrase 7	0	1	0	4
26S proteasome regulatory subunit 6B	0	1	3	4
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
Carbonic anhydrase 9	0	1	0	4
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Carbonic anhydrase 14	0	1	0	4
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	4
Nuclear hormone receptor family member daf-12	0	0	1	1
oxysterols receptor LXR-beta isoform 1	0	0	1	1
Thymidine kinase, cytosolic	0	1	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Cytochrome P450 2E1	0	1	0	1
hypoxia-inducible factor 1 alpha subunit	8	0	0	8
SMAD family member 2	8	0	0	8
SMAD family member 3	8	0	0	8
apical membrane antigen 1, AMA1	4	0	0	4
G	9	0	0	9
cytochrome P450 2D6	13	0	0	13
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	9	0	0	9
NPC intracellular cholesterol transporter 1 precursor	4	0	0	4
HLA class I histocompatibility antigen, B alpha chain	9	0	0	9
Trypanothione reductase	0	3	0	3
Inositol hexakisphosphate kinase 1	9	0	0	9
cytochrome P450 2C9, partial	9	0	0	9
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	2	4	6
Replicase polyprotein 1ab	0	2	4	6
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	2	4	6
Dihydrofolate reductase	0	1	0	1
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	0	1	1
Major prion protein	0	0	3	3
Amyloid-beta precursor protein	0	5	0	6
Histidine-rich protein PFHRP-II	0	1	0	2
Procathepsin L	0	2	4	6
Muscarinic acetylcholine receptor M2	0	6	0	6
Muscarinic acetylcholine receptor M4	0	5	0	5
Muscarinic acetylcholine receptor M5	0	5	0	5
Alpha-2A adrenergic receptor	0	7	0	7
Replicase polyprotein 1a	0	2	4	6
Replicase polyprotein 1ab	0	2	4	6
Spike glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M1	0	5	0	5
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	3	4
Alpha-2C adrenergic receptor	0	7	0	7
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	6	0	6
Serine/threonine-protein kinase mTOR	0	2	2	4
Beta-secretase 1	0	3	0	3
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	2	0	2
DNA ligase A	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	13	0	13
Sigma intracellular receptor 2	0	2	0	2
Phosphoethanolamine N-methyltransferase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	5	0	5
Angiotensin-converting enzyme 2	0	2	4	6
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
NADPH oxidase 1	0	1	0	1
Snq2p	0	0	0	2
Adenylate cyclase type 1	0	2	0	2
cytochrome P450 2D6 isoform 1	7	0	0	7
histone deacetylase 9 isoform 3	4	0	0	4
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
M-phase phosphoprotein 8	4	0	0	4
Solute carrier family 22 member 1	0	4	0	6
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Transient receptor potential cation channel subfamily V member 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
Bile salt export pump	0	4	0	4
5-hydroxytryptamine receptor 4	0	6	0	6
Potassium channel subfamily K member 2	0	1	1	2
Albumin	0	2	2	4
Albumin	0	0	3	3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	4	0	4
Major prion protein	0	0	1	1
Cytochrome P450 1A2	0	1	1	3
Aldo-keto reductase family 1 member B1	0	7	0	7
ATP-dependent translocase ABCB1	0	6	1	9
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
5-hydroxytryptamine receptor 1A	0	3	2	5
Muscarinic acetylcholine receptor M5	0	2	0	2
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	2	1	3
Cytochrome P450 2D6	0	5	1	6
Muscarinic acetylcholine receptor M2	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Angiotensin-converting enzyme	0	4	0	4
D(2) dopamine receptor	0	6	1	8
Sphingomyelin phosphodiesterase	0	2	0	2
D	0	4	0	4
D(3) dopamine receptor	0	4	0	4
Alpha-2B adrenergic receptor	0	6	0	6
D(2) dopamine receptor	0	1	0	1
Substance-K receptor	0	4	0	4
D(1A) dopamine receptor	0	4	0	5
D(4) dopamine receptor	0	3	0	4
D(1B) dopamine receptor	0	1	0	2
Adenylate cyclase type 3	0	2	0	2
Alpha-2C adrenergic receptor	0	6	0	6
UDP-glucuronosyltransferase 1A4	0	1	0	3
Alpha-2A adrenergic receptor	0	6	0	6
Sodium-dependent noradrenaline transporter	0	8	0	8
Sodium-dependent dopamine transporter	0	4	0	4
Histamine H2 receptor	0	5	0	5
Alpha-1D adrenergic receptor	0	6	0	6
D(1B) dopamine receptor	0	3	0	3
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
5-hydroxytryptamine receptor 2A	0	8	0	8
5-hydroxytryptamine receptor 2C	0	7	0	7
D(4) dopamine receptor	0	3	0	3
Histamine H1 receptor	0	3	0	3
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	2	0	4
5-hydroxytryptamine receptor 7	0	3	0	3
Histamine H1 receptor	0	7	0	7
D(3) dopamine receptor	0	4	0	5
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 4 subunit alpha	0	2	0	2
Adenylate cyclase type 8	0	2	0	2
5-hydroxytryptamine receptor 2B	0	4	0	4
Melanocortin receptor 3	0	2	0	2
5-hydroxytryptamine receptor 6	0	4	0	4
5-hydroxytryptamine receptor 7	0	2	0	2
Cytochrome P450 2J2	0	4	0	4
Gastrin/cholecystokinin type B receptor	0	1	0	1
D(2) dopamine receptor	0	5	0	6
Aldehyde oxidase 1	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Sodium-dependent dopamine transporter	0	7	0	7
Adenylate cyclase type 6	0	2	0	2
Adenylate cyclase type 5	0	2	0	2
Aldehyde oxidase	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Sodium channel protein type 5 subunit alpha	0	3	0	3
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	2	0	2
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
Adenylyl cyclase 7	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	2	0	2
Histamine H3 receptor	0	5	2	8
Sodium channel protein type 10 subunit alpha	0	2	0	2
Delta(24)-sterol reductase	0	1	3	5
Oxysterols receptor LXR-beta	0	0	2	2
Cholesterol 24-hydroxylase	0	1	1	2
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	3	0	5
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	2	1	0	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	2	1	0	3
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	5	2	7
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	1	0	2
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Solute carrier family 22 member 1	0	2	0	3
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	2	0	3
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Chain A, Breast cancer type 1 susceptibility protein	2	0	0	2
Luciferase	12	0	0	12
Nrf2	2	0	0	2
alkaline phosphatase, intestinal	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	6	0	0	6
PINK1	4	0	0	4
toll-like receptor 9	0	1	0	1
TPA: protein transporter TIM10	0	1	0	1
thyrotropin-releasing hormone receptor	3	0	0	3
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
perilipin-5	0	1	0	1
intestinal alkaline phosphatase precursor	0	1	0	1
perilipin-1	0	1	0	1
transcriptional regulator ERG isoform 3	5	0	0	5
importin subunit beta-1 isoform 1	5	0	0	5
DNA polymerase beta	4	0	0	4
nuclear factor NF-kappa-B p105 subunit isoform 1	3	0	0	3
snurportin-1	5	0	0	5
histone-lysine N-methyltransferase 2A isoform 2 precursor	6	0	0	6
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
tumor susceptibility gene 101 protein	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
muscleblind-like protein 1 isoform 1	4	0	0	4
alkaline phosphatase, germ cell type preproprotein	0	1	0	1
hypothetical protein SA1422	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	3	0	0	3
neuropeptide S receptor isoform A	6	0	0	6
Prostaglandin E synthase	0	1	0	1
Acetylcholinesterase	0	7	0	7
Lysine-specific histone demethylase 1A	0	2	0	2
D-amino-acid oxidase	0	1	0	1
Phospholipase A2	0	1	0	1
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Cholinesterase	0	4	0	4
Heme oxygenase 1	0	1	0	1
Glutathione S-transferase P	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Microtubule-associated protein tau	0	1	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Glycogen synthase kinase-3 beta	0	1	0	1
Amine oxidase [flavin-containing] A	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Heme oxygenase 2	0	1	0	1
Amine oxidase [flavin-containing] B	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	2	0	2
Alpha-synuclein	6	1	1	8
Glycogen synthase kinase-3 beta	0	3	3	6
Cholinesterase	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Lactoylglutathione lyase	0	1	0	1
Histone acetyltransferase p300	0	1	0	1
TAR DNA-binding protein 43	11	0	0	11
Serine/threonine-protein kinase PAK 1	0	1	1	2
5-hydroxytryptamine receptor 4	0	0	1	1
Sodium/bile acid cotransporter	0	2	1	3
Nuclear factor erythroid 2-related factor 2	0	0	1	1
Thioredoxin reductase 1, cytoplasmic	0	1	0	1
Thioredoxin reductase 3	0	1	0	1
Sortase A	0	1	0	1
CREB-binding protein	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	5	0	5
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	1	0	1
Interferon regulatory factor 3	0	0	1	1
Stimulator of interferon genes protein	0	0	2	2
Stimulator of interferon genes protein	0	1	2	3
Alpha-tocopherol transfer protein	0	0	1	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
Beta-glucuronidase	0	1	0	1
Beta-glucuronidase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	3	0	3
G-protein coupled bile acid receptor 1	0	0	3	3
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	2
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Steryl-sulfatase	0	0	0	1
Multidrug resistance-associated protein 1	0	0	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	2
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Solute carrier family 22 member 11	0	0	0	2
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	2
prostaglandin E2 receptor EP2 subtype	1	0	0	2
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier family 22 member 6	0	1	0	2
Solute carrier family 22 member 7	0	0	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 8	0	1	0	2
Solute carrier family 22 member 6	0	3	0	3
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
acid sphingomyelinase	3	0	0	3
RGS12	1	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
DNA polymerase III, partial	1	0	0	1
isocitrate dehydrogenase 1, partial	2	0	0	2
nonstructural protein 1	4	0	0	4
LANA	0	0	0	1
serine-protein kinase ATM isoform a	2	0	0	2
cytochrome P450 2C9 precursor	6	0	0	6
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
eyes absent homolog 2 isoform a	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
kelch-like ECH-associated protein 1	0	0	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Multidrug resistance-associated protein 5	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	2	0	2
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Exopolyphosphatase PRUNE1	0	1	0	1
Multidrug and toxin extrusion protein 2	0	3	0	3
Rap guanine nucleotide exchange factor 4	5	0	0	5
Single-stranded DNA cytosine deaminase	1	0	0	1
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
Acetylcholinesterase	0	1	0	1
Amine oxidase [flavin-containing] A	0	2	0	2
Amine oxidase [flavin-containing] A	0	2	0	2
Acetylcholinesterase	0	1	0	1
Liver carboxylesterase 1	0	2	0	2
Acetylcholinesterase	0	2	0	2
Acetylcholinesterase	0	2	0	2
Cholinesterase	0	1	0	1
Acetylcholine receptor subunit epsilon	0	1	0	1
Cytochrome P450 1B1	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	3	0	3
Acyl-CoA:cholesterol acyltransferase	0	2	0	2
Carboxylic ester hydrolase	0	2	0	2
Carboxylic ester hydrolase	0	2	0	2
Eyes absent homolog 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	2	0	5
UDP-glucuronosyltransferase 1A1	0	2	0	3
UDP-glucuronosyltransferase 1A3	0	0	0	3
NPC1-like intracellular cholesterol transporter 1	0	1	0	1
Gamma-aminobutyric acid	0	0	2	2
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	2	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	2	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	2	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	2	2
Gamma-aminobutyric acid receptor subunit delta	0	0	2	2
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	2	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	0	2	2
Gamma-aminobutyric acid receptor subunit beta-3	0	2	2	4
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	2	4
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	2	4
Gamma-aminobutyric acid receptor subunit beta-2	0	2	2	4
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	2	4
Gamma-aminobutyric acid receptor subunit beta-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	2	3
Gamma-aminobutyric acid receptor subunit beta-3	0	0	2	2
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	2	4
Sterol O-acyltransferase 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	2	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	0	2	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	2	2
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	0	2	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
Chain A, Estrogen receptor 1 (alpha)	0	1	0	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
BRCA1	1	0	0	1
Neuraminidase	0	1	0	1
P53	1	0	0	1
pyruvate kinase	4	0	0	4
hexokinase-4 isoform 1	2	0	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	5	0	0	5
glucokinase regulatory protein	2	0	0	2
tyrosine-protein kinase Yes	3	0	0	3
pyruvate kinase PKM isoform b	3	0	0	3
Steroid hormone receptor ERR2	0	1	0	1
Tyrosine-protein kinase ABL1	0	5	5	10
Pancreatic triacylglycerol lipase	0	1	0	1
Triosephosphate isomerase	0	1	0	1
Transthyretin	0	1	0	1
Glucocorticoid receptor	0	0	1	2
Cyclin-dependent kinase 1	0	2	3	5
Ornithine decarboxylase	3	0	0	3
Sialidase	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 1	0	1	0	1
Tyrosinase	0	1	0	1
Steroid hormone receptor ERR1	0	1	0	1
Cyclin-dependent kinase 4	0	1	3	4
Ornithine decarboxylase	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
17-beta-hydroxysteroid dehydrogenase type 1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Protein kinase C alpha type	0	1	3	5
cAMP-dependent protein kinase catalytic subunit alpha	0	4	3	7
Prostaglandin G/H synthase 1	0	3	0	3
G1/S-specific cyclin-D1	0	1	0	1
Thromboxane-A synthase	0	1	0	1
Cruzipain	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Substance-P receptor	0	3	0	3
RAC-alpha serine/threonine-protein kinase	0	1	3	4
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Signal transducer and activator of transcription 3	0	1	0	1
Tyrosine-protein kinase CSK	0	2	3	5
Tyrosine-protein kinase ABL2	0	1	3	4
Tyrosine-protein kinase SYK	0	1	3	4
Dual specificity mitogen-activated protein kinase kinase 4	0	1	1	2
Quinone oxidoreductase	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Cytoplasmic tyrosine-protein kinase BMX	0	1	1	2
Death-associated protein kinase 1	0	1	1	2
Mitogen-activated protein kinase 10	0	1	3	4
Amine oxidase [flavin-containing] B	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Mitogen-activated protein kinase 14	0	2	3	5
Tissue alpha-L-fucosidase	0	1	0	1
Substance-K receptor	0	1	0	1
Integrase	0	1	0	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	1	0	1
Prenyltransferase homolog	0	0	0	1
Dipeptidyl peptidase 3	0	1	0	1
DNA (cytosine-5)-methyltransferase 3-like	0	1	0	1
Sialidase-2	0	1	0	1
DNA (cytosine-5)-methyltransferase 3A	0	1	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Glutathione reductase, mitochondrial	0	4	0	4
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	2	1	3
Glutamate receptor 3	0	2	1	3
Glutamate receptor 4	0	2	1	3
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	2	0	2
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Glycine receptor subunit alpha-1	0	0	2	2
Sodium- and chloride-dependent glycine transporter 1	0	2	0	2
Large neutral amino acids transporter small subunit 1	0	6	0	6
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	2	2
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	2	3	5
Plasma kallikrein	0	0	2	5
Retinoic acid receptor RXR-alpha	0	1	2	3
Genome polyprotein	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Acid-sensing ion channel 3	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Dihydrofolate reductase	0	4	0	4
Fatty acid-binding protein, liver	0	2	0	2
Fatty acid-binding protein, intestinal	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Caspase-1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	2
Aldo-keto reductase family 1 member C3	0	1	0	1
Caspase-3	0	1	0	1
Caspase-4	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Caspase-5	0	1	0	1
Caspase-9	0	1	0	1
Acid-sensing ion channel 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	2
Dehydrogenase/reductase SDR family member 9	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Cytochrome P450 2C8	0	1	0	2
Mast/stem cell growth factor receptor Kit	0	4	3	7
Breakpoint cluster region protein	0	2	5	7
Platelet-derived growth factor receptor alpha	0	2	2	4
Cytochrome P450 3A5	0	1	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium-dependent noradrenaline transporter	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Histamine H1 receptor	0	1	0	1
Cytochrome P450 2C19	0	3	0	4
5-hydroxytryptamine receptor 2C	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Envelope glycoprotein	0	0	1	1
Sigma intracellular receptor 2	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Transporter	0	3	0	3
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, Galectin-3	0	0	1	1
Chain A, Anti-tumor lectin	0	1	0	1
Galectin-3	0	1	0	1
Galectin-9	0	0	1	1
Galectin-8	0	0	1	1
Beta-galactoside-binding lectin	0	1	0	1
Galectin-1	0	1	1	3
Galectin-3	0	1	1	2
Galectin-3	0	1	1	3
Galectin-7	0	0	1	1
Alpha 1,4 galactosyltransferase	0	0	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Intestinal-type alkaline phosphatase	0	2	0	2
Phospholipase A-2-activating protein	0	2	0	2
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
DNA polymerase eta isoform 1	2	0	0	2
Solute carrier family 15 member 1	0	1	0	1
Carbonic anhydrase	0	0	0	3
SLC16A10 protein	0	0	0	3
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	0	0	3
Monocarboxylate transporter 10	0	0	0	3
Carbonic anhydrase 13	0	0	0	2
phosphoglycerate kinase	1	0	0	1
Chain A, Antigen Cd11a (p180)	0	1	0	1
bcl-2-related protein A1	0	2	0	2
Integrin beta-2	0	1	0	1
Intercellular adhesion molecule 1	0	1	0	1
Insulin receptor	0	2	0	2
Integrin alpha-L	0	1	1	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	4	0	4
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Cationic amino acid transporter 3	0	1	0	1
Potassium channel subfamily K member 9	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Translocator protein	0	3	1	4
UDP-glucuronosyltransferase 1-6	0	1	0	2
ATP-dependent translocase ABCB1	0	1	0	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
Sucrase-isomaltase	0	1	0	1
Ceramide glucosyltransferase	0	1	0	1
Beta-galactosidase	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Non-lysosomal glucosylceramidase	0	1	0	1
Chain A, Adipocyte Lipid-binding Protein	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	2	2
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	2	2
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	2	2
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
putative potassium channel subunit	0	0	1	1
bcl-2-like protein 11 isoform 1	0	0	1	1
Sterol O-acyltransferase 1	0	1	0	1
Fatty acid-binding protein, liver	0	0	1	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
DNA topoisomerase 1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	3	0	3
Peroxisome proliferator-activated receptor delta	0	0	0	1
Peroxisome proliferator-activated receptor alpha	2	0	3	5
Chain A, Fatty acid-binding protein, adipocyte	0	1	0	1
Toll-like receptor 2	0	1	0	1
Histone deacetylase 8	0	2	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	1	2
Bromodomain-containing protein 4	0	2	0	2
Protein Tat	0	0	2	2
Leukotriene A-4 hydrolase	0	2	0	2
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	2	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	1	2
NAD-dependent protein deacetylase sirtuin-2	0	2	0	2
NAD-dependent protein deacetylase sirtuin-1	0	2	0	2
NAD-dependent protein deacetylase sirtuin-7	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	2	0	2
Histone deacetylase	0	2	0	2
Nuclear receptor corepressor 2	0	3	0	3
RAF proto-oncogene serine/threonine-protein kinase	0	1	1	2
Luciferin 4-monooxygenase	0	1	0	1
Mitogen-activated protein kinase 3	0	0	3	4
Mitogen-activated protein kinase 1	0	1	3	4
Dual specificity mitogen-activated protein kinase kinase 2	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	3	4
Phenylethanolamine N-methyltransferase	0	0	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	2	1	3
endonuclease IV	2	0	0	2
Translocator protein	0	2	1	4
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Bone morphogenetic protein receptor type-1B	0	0	3	3
Serine/threonine-protein kinase PLK4	0	0	3	3
ATP-dependent RNA helicase DDX3X	0	0	3	3
Pyridoxal kinase	0	0	3	3
Citron Rho-interacting kinase	0	0	3	3
Serine/threonine-protein kinase Chk1	0	0	3	3
Aurora kinase A	0	0	3	3
Cyclin-G-associated kinase	0	0	3	3
Ephrin type-B receptor 6	0	0	3	3
Peroxisomal acyl-coenzyme A oxidase 3	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 2	0	1	3	4
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	3	3
Dynamin-like 120 kDa protein, mitochondrial	0	0	3	3
Tyrosine-protein kinase JAK2	0	2	2	4
Rho-associated protein kinase 2	0	2	3	5
Serine/threonine-protein kinase ULK1	0	0	3	3
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	3	3
Ribosomal protein S6 kinase alpha-5	0	1	3	4
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	3	3
Ribosomal protein S6 kinase alpha-4	0	0	3	3
Serine/threonine-protein kinase 16	0	0	3	3
Serine/threonine-protein kinase 10	0	0	3	3
Serine/threonine-protein kinase D3	0	0	3	3
Structural maintenance of chromosomes protein 2	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	3	3
Serine/threonine-protein kinase LATS1	0	0	3	3
Serine/threonine-protein kinase PAK 4	0	0	3	3
Proto-oncogene tyrosine-protein kinase Src	0	1	1	2
High affinity nerve growth factor receptor	0	1	2	3
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	2	2
ADP/ATP translocase 2	0	0	3	3
Protein kinase C beta type	0	0	3	3
Glycogen phosphorylase, liver form	0	0	3	3
Tyrosine-protein kinase Fes/Fps	0	0	3	3
Macrophage colony-stimulating factor 1 receptor	0	1	1	2
Adenine phosphoribosyltransferase	0	0	2	2
Tyrosine-protein kinase Yes	0	1	3	4
Tyrosine-protein kinase Lyn	0	1	3	4
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	3	4
Insulin-like growth factor 1 receptor	0	2	3	5
Signal recognition particle receptor subunit alpha	0	0	3	3
Cytochrome c1, heme protein, mitochondrial	0	0	3	3
Hepatocyte growth factor receptor	0	2	3	5
Tyrosine-protein kinase HCK	0	1	3	4
Tyrosine-protein kinase Fgr	0	0	3	3
Serine/threonine-protein kinase A-Raf	0	0	3	3
Glycogen phosphorylase, brain form	0	0	3	3
Serine/threonine-protein kinase pim-1	0	0	3	3
DNA topoisomerase 2-alpha	0	0	3	3
ADP/ATP translocase 3	0	0	3	3
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	3	3
Serine/threonine-protein kinase B-raf	0	0	3	3
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	3	3
Tyrosine-protein kinase Fer	0	0	3	3
Vascular endothelial growth factor receptor 1	0	2	1	3
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	3	3
Casein kinase II subunit alpha'	0	0	3	3
Ras-related protein Rab-6A	0	0	3	3
Ephrin type-A receptor 1	0	1	3	4
Multifunctional protein ADE2	0	0	3	3
cAMP-dependent protein kinase catalytic subunit gamma	0	2	2	4
cAMP-dependent protein kinase catalytic subunit beta	0	2	3	5
Ferrochelatase, mitochondrial	0	0	3	3
Ribosomal protein S6 kinase beta-1	0	0	3	3
Tyrosine-protein kinase JAK1	0	1	3	4
Cyclin-dependent kinase 2	0	0	3	3
Beta-adrenergic receptor kinase 1	0	0	3	3
Probable ATP-dependent RNA helicase DDX6	0	0	3	3
MAP/microtubule affinity-regulating kinase 3	0	0	3	3
Deoxycytidine kinase	0	0	3	3
Ephrin type-B receptor 2	0	0	3	3
Leukocyte tyrosine kinase receptor	0	1	1	2
Non-receptor tyrosine-protein kinase TYK2	0	0	3	3
Phosphatidylethanolamine-binding protein 1	0	0	2	2
Wee1-like protein kinase	0	0	3	3
Heme oxygenase 2	0	0	3	3
S-adenosylmethionine synthase isoform type-2	0	0	2	2
DnaJ homolog subfamily A member 1	0	0	3	3
RAC-beta serine/threonine-protein kinase	0	0	3	3
Dual specificity protein kinase TTK	0	0	3	3
DNA replication licensing factor MCM4	0	0	3	3
Myosin-10	0	0	3	3
Vascular endothelial growth factor receptor 2	0	3	1	5
Dual specificity mitogen-activated protein kinase kinase 2	0	0	3	3
Receptor-type tyrosine-protein kinase FLT3	0	2	3	5
Bone morphogenetic protein receptor type-1A	0	0	3	3
Activin receptor type-1B	0	0	3	3
TGF-beta receptor type-1	0	0	3	3
Serine/threonine-protein kinase receptor R3	0	0	3	3
TGF-beta receptor type-2	0	0	3	3
Electron transfer flavoprotein subunit beta	0	0	3	3
Glycine--tRNA ligase	0	0	3	3
Protein kinase C iota type	0	0	3	3
Exosome RNA helicase MTR4	0	0	3	3
Tyrosine-protein kinase Tec	0	0	3	3
Tyrosine-protein kinase FRK	0	1	3	4
Mitogen-activated protein kinase 8	0	0	3	3
Mitogen-activated protein kinase 9	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 3	0	0	3	3
Casein kinase I isoform alpha	0	0	3	3
Casein kinase I isoform delta	0	0	3	3
MAP kinase-activated protein kinase 2	0	0	3	3
Elongation factor Tu, mitochondrial	0	0	3	3
Cysteine--tRNA ligase, cytoplasmic	0	0	3	3
Casein kinase I isoform epsilon	0	0	3	3
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	3	3
Dual specificity protein kinase CLK1	0	0	3	3
Dual specificity protein kinase CLK2	0	0	3	3
Glycogen synthase kinase-3 alpha	0	0	3	3
Cyclin-dependent kinase 7	0	0	3	3
Cyclin-dependent kinase 9	0	0	3	3
Ras-related protein Rab-27A	0	0	3	3
Interleukin-1 receptor-associated kinase 1	0	0	3	3
Ribosomal protein S6 kinase alpha-3	0	0	3	3
Serine/threonine-protein kinase Nek2	0	0	3	3
Serine/threonine-protein kinase Nek3	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 6	0	0	3	3
Serine/threonine-protein kinase PLK1	0	0	3	3
LIM domain kinase 1	0	0	3	3
LIM domain kinase 2	0	0	3	3
Tyrosine--tRNA ligase, cytoplasmic	0	0	3	3
Ephrin type-B receptor 3	0	0	3	3
Ephrin type-A receptor 5	0	0	3	3
Ephrin type-B receptor 4	0	0	3	3
Ephrin type-A receptor 4	0	0	3	3
Ras-related protein Rab-10	0	0	3	3
Actin-related protein 3	0	0	3	3
Actin-related protein 2	0	0	3	3
GTP-binding nuclear protein Ran	0	0	3	3
Casein kinase I isoform gamma-2	0	0	3	3
Cyclin-dependent kinase 3	0	0	2	2
Cyclin-dependent kinase 6	0	0	3	3
Cyclin-dependent-like kinase 5	0	0	3	3
Cyclin-dependent kinase 16	0	0	3	3
Cyclin-dependent kinase 17	0	0	3	3
ATP-dependent 6-phosphofructokinase, platelet type	0	0	3	3
DNA topoisomerase 2-beta	0	0	3	3
Activin receptor type-1	0	0	3	3
Macrophage-stimulating protein receptor	0	0	3	3
Focal adhesion kinase 1	0	0	3	3
Protein kinase C delta type	0	0	3	3
Tyrosine-protein kinase BTK	0	0	3	3
Activated CDC42 kinase 1	0	0	3	3
Epithelial discoidin domain-containing receptor 1	0	1	3	4
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	3	3
Serine/threonine-protein kinase 4	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 5	0	0	3	3
Mitogen-activated protein kinase 7	0	0	3	3
Serine/threonine-protein kinase PAK 2	0	0	3	3
Serine/threonine-protein kinase 3	0	0	3	3
Mitogen-activated protein kinase kinase kinase 1	0	0	3	3
Integrin-linked protein kinase	0	0	3	3
Rho-associated protein kinase 1	0	2	3	5
Non-receptor tyrosine-protein kinase TNK1	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 1	0	1	1	2
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	3	3
Activin receptor type-2B	0	0	3	3
Bone morphogenetic protein receptor type-2	0	0	3	3
Protein-tyrosine kinase 6	0	0	3	3
Cyclin-dependent kinase 13	0	0	3	3
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	3	3
Protein-tyrosine kinase 2-beta	0	0	3	3
Maternal embryonic leucine zipper kinase	0	0	3	3
Structural maintenance of chromosomes protein 1A	0	0	3	3
Chromodomain-helicase-DNA-binding protein 4	0	0	3	3
Peroxisomal acyl-coenzyme A oxidase 1	0	0	3	3
Ribosomal protein S6 kinase alpha-1	0	0	3	3
Dual specificity testis-specific protein kinase 1	0	0	3	3
Myosin light chain kinase, smooth muscle	0	0	3	3
Mitogen-activated protein kinase 11	0	0	3	3
Serine/threonine-protein kinase STK11	0	0	3	3
Coiled-coil domain-containing protein 6	0	1	0	1
Serine/threonine-protein kinase N1	0	0	3	3
Serine/threonine-protein kinase N2	0	1	3	4
Calcium/calmodulin-dependent protein kinase type IV	0	0	3	3
Mitogen-activated protein kinase kinase kinase 11	0	0	3	3
Discoidin domain-containing receptor 2	0	0	3	3
AP2-associated protein kinase 1	0	0	3	3
Uncharacterized aarF domain-containing protein kinase 5	0	0	3	3
Putative heat shock protein HSP 90-beta 2	0	0	3	3
Leucine-rich repeat serine/threonine-protein kinase 2	0	1	1	2
Serine/threonine-protein kinase MRCK alpha	0	0	3	3
Serine/threonine-protein kinase MRCK gamma	0	0	3	3
Acyl-CoA dehydrogenase family member 10	0	0	3	3
Serine/threonine-protein kinase ULK3	0	0	3	3
Uncharacterized protein FLJ45252	0	0	3	3
Acyl-CoA dehydrogenase family member 11	0	0	3	3
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	3	3
Serine/threonine-protein kinase MARK2	0	0	3	3
Serine/threonine-protein kinase TAO1	0	0	3	3
STE20-related kinase adapter protein alpha	0	0	3	3
Myosin-14	0	0	3	3
AarF domain-containing protein kinase 1	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	3	3
MAP kinase-activated protein kinase 5	0	0	3	3
Atypical kinase COQ8A, mitochondrial	0	0	3	3
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	3	3
Mitogen-activated protein kinase 15	0	0	3	3
Serine/threonine-protein kinase Nek9	0	0	3	3
ATP-dependent RNA helicase DDX1	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	3	3
Aurora kinase B	0	0	3	3
MAP/microtubule affinity-regulating kinase 4	0	0	3	3
Serine/threonine-protein kinase Nek1	0	0	3	3
PAS domain-containing serine/threonine-protein kinase	0	0	3	3
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	3	3
EKC/KEOPS complex subunit TP53RK	0	0	3	3
Dual specificity testis-specific protein kinase 2	0	0	3	3
Protein cereblon	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	3	3
Mitogen-activated protein kinase kinase kinase 5	0	0	3	3
Mitogen-activated protein kinase kinase kinase 3	0	0	3	3
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	3	3
Serine/threonine-protein kinase D2	0	0	3	3
NUAK family SNF1-like kinase 2	0	0	2	2
RNA cytidine acetyltransferase	0	0	3	3
Serine/threonine-protein kinase SIK2	0	0	3	3
STE20-like serine/threonine-protein kinase	0	0	3	3
Serine/threonine-protein kinase TAO3	0	0	3	3
dCTP pyrophosphatase 1	0	0	3	3
Casein kinase I isoform gamma-1	0	0	3	3
Serine/threonine-protein kinase PAK 6	0	0	2	2
Phenylalanine--tRNA ligase beta subunit	0	0	3	3
BMP-2-inducible protein kinase	0	0	3	3
Obg-like ATPase 1	0	0	2	2
Midasin	0	0	3	3
Interleukin-1 receptor-associated kinase 4	0	0	3	3
Mitogen-activated protein kinase kinase kinase 20	0	0	3	3
Cyclin-dependent kinase 12	0	0	3	3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	2	2
Serine/threonine-protein kinase pim-2	0	0	2	2
Serine/threonine-protein kinase 26	0	0	3	3
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	2	2
Serine/threonine-protein kinase NLK	0	0	3	3
Serine/threonine-protein kinase TBK1	0	0	3	3
Septin-9	0	0	3	3
Ribosomal protein S6 kinase alpha-6	0	0	3	3
TRAF2 and NCK-interacting protein kinase	0	0	3	3
Serine/threonine-protein kinase TAO2	0	0	3	3
Long-chain-fatty-acid--CoA ligase 5	0	0	2	2
Serine/threonine-protein kinase ICK	0	0	3	3
RAC-gamma serine/threonine-protein kinase	0	0	3	3
Serine/threonine-protein kinase SIK3	0	0	3	3
Mitogen-activated protein kinase kinase kinase 2	0	0	3	3
Thyroid hormone receptor-associated protein 3	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 3	0	1	3	4
Serine/threonine-protein kinase MRCK beta	0	0	3	3
Interleukin-1 receptor-associated kinase 3	0	0	3	3
Casein kinase I isoform gamma-3	0	0	3	3
Mitogen-activated protein kinase kinase kinase 4	0	0	3	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	2
Vascular cell adhesion protein 1	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	3	0	3
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Pteridine reductase 1	0	2	0	2
Beta-1 adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Transporter	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
NS5	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Pyruvate kinase PKM	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	2	2
Eukaryotic translation initiation factor 5B	0	0	2	2
Cyclin-dependent kinase-like 5	0	0	2	2
Mitogen-activated protein kinase kinase kinase 6	0	0	2	2
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
UMP-CMP kinase	0	0	1	1
G protein-coupled receptor kinase 6	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	2	2
Choline-phosphate cytidylyltransferase A	0	0	2	2
Dual specificity protein kinase CLK3	0	0	2	2
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Protein kinase C theta type	0	0	2	2
Protein kinase C zeta type	0	0	2	2
Cyclin-dependent kinase 18	0	0	2	2
Tyrosine-protein kinase Mer	0	0	2	2
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
cGMP-dependent protein kinase 1	0	0	2	2
Myosin light chain kinase 3	0	0	2	2
Programmed cell death protein 4	0	0	1	1
Serine/threonine-protein kinase N3	0	0	2	2
ATP-dependent RNA helicase DHX30	0	0	2	2
Regulatory-associated protein of mTOR	0	1	0	1
Misshapen-like kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1G	0	0	2	2
Target of rapamycin complex subunit LST8	0	1	0	1
Nucleolar GTP-binding protein 1	0	0	2	2
Dual specificity protein kinase CLK4	0	0	2	2
Serine/threonine-protein kinase mTOR	0	1	0	1
Isoleucine--tRNA ligase, mitochondrial	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	2	2
Serine/threonine-protein kinase 24	0	0	2	2
C-X-C chemokine receptor type 5 isoform 1	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
C-C chemokine receptor type 6	0	1	0	1
apelin receptor	0	1	0	1
streptokinase A precursor	0	0	1	1
Endoglycoceramidase II	0	0	0	1
Protein kinase C alpha type	0	1	0	1
Estrogen receptor	0	0	1	1
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Estrogen receptor beta	0	0	1	1
Protein kinase C eta type	0	1	0	1
Sphingosine kinase 2	0	1	0	1
Sphingosine kinase 1	0	1	0	1
Protein kinase C theta type	0	1	0	1
Sphingosine 1-phosphate receptor 2	0	1	1	2
Sphingosine 1-phosphate receptor 4	0	1	1	2
Sphingosine 1-phosphate receptor 1	0	1	1	2
Sphingosine 1-phosphate receptor 3	0	1	1	2
Sphingosine 1-phosphate receptor 5	0	1	1	2
Chain A, Ribosomal protein S6 kinase alpha-1	0	1	0	1
Chain X, Tyrosine-protein kinase Lyn	0	1	0	1
Chain A, Dual specificity protein kinase TTK	0	0	1	1
Chain A, Dual specificity protein kinase TTK	0	0	1	1
Chain A, Oxysterols receptor LXR-beta	0	1	0	1
Chain A, Oxysterols receptor LXR-beta	0	1	0	1
interferon gamma precursor	0	0	0	1
Nuclear receptor ROR-alpha	0	2	1	3
Presenilin-1	0	1	1	2
Presenilin-2	0	1	1	2
Oxysterols receptor LXR-beta	0	0	1	1
Gamma-secretase subunit APH-1B	0	1	1	2
Nicastrin	0	1	1	2
Nuclear receptor ROR-beta	0	1	1	2
Gamma-secretase subunit APH-1A	0	1	1	2
Bile acid receptor	0	1	2	3
GALC protein	2	0	0	2
Serine palmitoyltransferase 1	0	0	1	1
Serine palmitoyltransferase 2	0	1	0	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Histamine H3 receptor	0	1	1	2
Histamine H4 receptor	0	1	0	1
Histamine H4 receptor	0	1	1	2
Histamine H4 receptor	0	2	1	5
Histamine H3 receptor	0	1	0	1
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with trehalose	0	1	0	1
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with cellobiose	0	1	0	1
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with maltose	0	1	0	1
Trehalose-phosphatase	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Myeloperoxidase	0	1	0	1
Stromelysin-1	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Taste receptor type 2 member 14	0	0	0	1
Ubiquitin carboxyl-terminal hydrolase 2	0	1	0	1
Vitamin D3 receptor	0	1	1	2
Ileal sodium/bile acid cotransporter	0	1	0	1
M1-family alanyl aminopeptidase	0	1	0	1
Cocaine esterase	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Cytochrome P450 2A6	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Leukotriene C4 synthase	0	0	1	1
Membrane-associated progesterone receptor component 1	0	0	1	1
Serine/threonine-protein kinase 25	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	1	1
Serine/threonine-protein kinase RIO3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 7	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	1	1
Peripheral plasma membrane protein CASK	0	0	1	1
Serine/threonine-protein kinase DCLK1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	1	1
Muscle, skeletal receptor tyrosine-protein kinase	0	0	1	1
Mitogen-activated protein kinase 13	0	0	1	1
3-phosphoinositide-dependent protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 13	0	0	1	1
Death-associated protein kinase 3	0	0	1	1
NUAK family SNF1-like kinase 1	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	1	1
Serine/threonine-protein kinase PAK 3	0	0	1	1
Serine/threonine-protein kinase 17B	0	0	1	1
Cyclin-dependent kinase 14	0	0	1	1
Serine/threonine-protein kinase OSR1	0	0	1	1
Serine/threonine-protein kinase Chk2	0	0	1	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Proto-oncogene tyrosine-protein kinase ROS	0	0	1	1
Wee1-like protein kinase 2	0	0	1	1
Uncharacterized serine/threonine-protein kinase SBK3	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Insulin receptor-related protein	0	0	1	1
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	1	1
Serine/threonine-protein kinase MAK	0	0	1	1
Cyclin-dependent kinase 11B	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	0	1	1
Protein kinase C eta type	0	0	1	1
Activin receptor type-2A	0	0	1	1
Ephrin type-A receptor 3	0	0	1	1
Ephrin type-A receptor 8	0	0	1	1
Tyrosine-protein kinase receptor UFO	0	0	1	1
Mitogen-activated protein kinase 4	0	0	1	1
G protein-coupled receptor kinase 4	0	0	1	1
Tyrosine-protein kinase receptor Tie-1	0	0	1	1
Vascular endothelial growth factor receptor 3	0	1	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	1	2
Megakaryocyte-associated tyrosine-protein kinase	0	0	1	1
Tyrosine-protein kinase TXK	0	0	1	1
Tyrosine-protein kinase ZAP-70	0	0	1	1
Cyclin-dependent kinase 8	0	0	1	1
Tyrosine-protein kinase Blk	0	0	1	1
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	1	1
Serine/threonine-protein kinase Nek4	0	0	1	1
Tyrosine-protein kinase JAK3	0	0	1	1
Mitogen-activated protein kinase 12	0	0	1	1
Ephrin type-B receptor 1	0	0	1	1
Hormonally up-regulated neu tumor-associated kinase	0	0	1	1
Serine/threonine-protein kinase SIK1	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 4	0	0	1	1
Cell division control protein 2 homolog	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
Tubulin alpha-1A chain	0	0	1	1
Casein kinase II subunit alpha	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	1	1
SRSF protein kinase 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 9	0	0	1	1
Serine/threonine-protein kinase PknB	0	0	1	1
Cyclin-dependent kinase-like 1	0	0	1	1
Protein kinase C epsilon type	0	0	1	1
Angiopoietin-1 receptor	0	0	1	1
Mitogen-activated protein kinase kinase kinase 10	0	0	1	1
Tyrosine-protein kinase receptor TYRO3	0	0	1	1
Tyrosine-protein kinase ITK/TSK	0	0	1	1
Myotonin-protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 12	0	0	1	1
cGMP-dependent protein kinase 2	0	0	1	1
Serine/threonine-protein kinase PRP4 homolog	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1	0	0	1	1
Cyclin-dependent kinase 10	0	0	1	1
Serine/threonine-protein kinase D1	0	0	1	1
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	0	1	1
Ribosomal protein S6 kinase alpha-2	0	0	1	1
Ephrin type-A receptor 7	0	0	1	1
Rhodopsin kinase GRK1	0	0	1	1
NT-3 growth factor receptor	0	0	1	1
BDNF/NT-3 growth factors receptor	0	0	1	1
Mitogen-activated protein kinase 6	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 19	0	0	1	1
Serine/threonine-protein kinase TNNI3K	0	0	1	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Rab-like protein 3	0	0	1	1
Serine/threonine-protein kinase Nek5	0	0	1	1
Dual serine/threonine and tyrosine protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 15	0	0	1	1
Serine/threonine-protein kinase tousled-like 2	0	0	1	1
Serine/threonine-protein kinase 32C	0	0	1	1
Serine/threonine-protein kinase pim-3	0	0	1	1
ATP-dependent RNA helicase DDX42	0	0	1	1
Serine/threonine-protein kinase VRK2	0	0	1	1
Myosin light chain kinase family member 4	0	0	1	1
Homeodomain-interacting protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1D	0	0	1	1
Cyclin-dependent kinase-like 3	0	0	1	1
Serine/threonine-protein kinase BRSK2	0	0	1	1
Serine/threonine-protein kinase NIM1	0	0	1	1
Serine/threonine-protein kinase ULK2	0	0	1	1
Serine/threonine-protein kinase DCLK2	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	1	1
Casein kinase I isoform alpha-like	0	0	1	1
Homeodomain-interacting protein kinase 4	0	0	1	1
Myosin-IIIa	0	0	1	1
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	1	1
Serine/threonine-protein kinase Nek11	0	0	1	1
Serine/threonine-protein kinase BRSK1	0	0	1	1
Serine/threonine-protein kinase 35	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
Rhodopsin kinase GRK7	0	0	1	1
Serine/threonine-protein kinase 32A	0	0	1	1
Myosin-IIIb	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	1	1
Cyclin-dependent kinase-like 2	0	0	1	1
Serine/threonine-protein kinase Sgk3	0	0	1	1
Atypical kinase COQ8B, mitochondrial	0	0	1	1
Cyclin-dependent kinase 15	0	0	1	1
SRSF protein kinase 1	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	1	1
Serine/threonine-protein kinase RIO1	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO2	0	0	1	1
Cyclin-dependent kinase 19	0	0	1	1
Transient receptor potential cation channel subfamily M member 6	0	0	1	1
Testis-specific serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase 33	0	0	1	1
Serine/threonine-protein kinase DCLK3	0	0	1	1
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	1	1
Homeodomain-interacting protein kinase 2	0	0	1	1
Tyrosine-protein kinase Srms	0	0	1	1
Homeodomain-interacting protein kinase 3	0	0	1	1
Serine/threonine-protein kinase PLK3	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	1	1
Serine/threonine-protein kinase Nek6	0	0	1	1
SNF-related serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase LATS2	0	0	1	1
Serine/threonine-protein kinase 36	0	0	1	1
Serine/threonine-protein kinase 32B	0	0	1	1
Serine/threonine-protein kinase PLK2	0	0	1	1
Serine/threonine-protein kinase MARK1	0	0	1	1
Serine/threonine-protein kinase PAK 5	0	0	1	1
eIF-2-alpha kinase GCN2	0	0	1	1
Serine/threonine-protein kinase 17A	0	0	1	1
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	1	1
Ephrin type-A receptor 6	0	0	1	1
Death-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase tousled-like 1	0	0	1	1
ALK tyrosine kinase receptor	0	0	1	1
SRSF protein kinase 3	0	0	1	1
Cyclin-dependent kinase 11A	0	0	1	1
Aurora kinase C	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	1	1
Serine/threonine-protein kinase 38-like	0	0	1	1
Microtubule-associated serine/threonine-protein kinase 1	0	0	1	1
Chain A, Histone deacetylase-like amidohydrolase	0	1	0	1
Chain A, Histone deacetylase-like amidohydrolase	0	1	0	1
PAX8	0	0	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Histone deacetylase	0	1	0	1
Lysine-specific demethylase 4E	0	1	0	1
Gli1	0	1	0	1
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
steroidogenic factor 1	0	1	0	1
protein Wnt-3a precursor	0	1	0	1
Histone deacetylase 1	0	2	0	2
Nuclear receptor corepressor 1	0	2	0	2
Tubulin alpha-1A chain	0	1	0	1
Tubulin beta chain	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX12	0	0	0	1
Cannabinoid receptor 1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Apoptosis regulator BAX	0	0	1	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Histone deacetylase 1	0	1	0	1
Histone deacetylase	0	1	0	1
Renin	0	1	0	1
Histone deacetylase 3	0	1	0	1
Histone deacetylase-like amidohydrolase	0	2	1	3
Histone deacetylase	0	1	0	1
HD2 type histone deacetylase HDA106	0	2	0	2
Carboxypeptidase B2	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 4	0	1	0	1
REST corepressor 3	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase	0	1	0	1
Chain E, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain I, cAMP-dependent protein kinase inhibitor, alpha form	0	1	0	1
Chain B, Rho-associated protein kinase 1	0	1	0	1
Chain A, Rho-associated protein kinase 1	0	1	0	1
Chain A, Rho-associated protein kinase 1	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain I, cAMP-dependent protein kinase inhibitor alpha	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain I, cAMP-dependent protein kinase inhibitor alpha	0	1	0	1
Chain A, Rho-associated protein kinase 1	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
C-C motif chemokine 2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Chain A, Human Adenosine A2A receptor/T4 lysozyme chimera	0	0	1	1
Chain A, Adenosine receptor A2a	0	0	1	1
Chain A, Adenosine receptor A2a	0	0	1	1
Delta-type opioid receptor	0	1	0	1
Hexokinase-4	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Niemann-Pick Disease, Type C

Synonyms(1)

Research

Studies (494)

Protein Targets (1,875)

Niemann-Pick Disease, Type C

Synonyms(1)

Research

Studies (494)

Drugs Studied (202)

Protein Targets (1,875)