baclofen has been researched along with Niemann-Pick Disease, Type C in 1 studies
Niemann-Pick Disease, Type C: An autosomal recessive lipid storage disorder that is characterized by accumulation of CHOLESTEROL and SPHINGOMYELINS in cells of the VISCERA and the CENTRAL NERVOUS SYSTEM. Type C (or C1) and type D are allelic disorders caused by mutation of the NPC1 gene, which encodes a protein that mediates intracellular cholesterol transport from LYSOSOMES. Clinical signs include hepatosplenomegaly and chronic neurological symptoms. Type D is a variant in people with a Nova Scotia ancestry.
| Excerpt | Relevance | Reference |
|---|---|---|
| "His severe spasticity made positioning and care difficult, and intense pain required multiple hospitalizations." | 5.51 | The Palliative Use of Intrathecal Baclofen in Niemann-Pick Disease Type C. ( Buxton, K; Nimec, DL; Stone, SS; Ubeda Tikkanen, A; Ullrich, CK, 2019) |
| "His severe spasticity made positioning and care difficult, and intense pain required multiple hospitalizations." | 1.51 | The Palliative Use of Intrathecal Baclofen in Niemann-Pick Disease Type C. ( Buxton, K; Nimec, DL; Stone, SS; Ubeda Tikkanen, A; Ullrich, CK, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ubeda Tikkanen, A | 1 |
| Buxton, K | 1 |
| Ullrich, CK | 1 |
| Stone, SS | 1 |
| Nimec, DL | 1 |
1 other study available for baclofen and Niemann-Pick Disease, Type C
| Article | Year |
|---|---|
The Palliative Use of Intrathecal Baclofen in Niemann-Pick Disease Type C.
Topics: Baclofen; Child; Fatal Outcome; Humans; Infusion Pumps, Implantable; Injections, Spinal; Male; Muscl | 2019 |