ys 64 has been researched along with Niemann-Pick Disease, Type C in 1 studies
*Niemann-Pick Disease, Type C: An autosomal recessive lipid storage disorder that is characterized by accumulation of CHOLESTEROL and SPHINGOMYELINS in cells of the VISCERA and the CENTRAL NERVOUS SYSTEM. Type C (or C1) and type D are allelic disorders caused by mutation of the NPC1 gene, which encodes a protein that mediates intracellular cholesterol transport from LYSOSOMES. Clinical signs include hepatosplenomegaly and chronic neurological symptoms. Type D is a variant in people with a Nova Scotia ancestry. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dodo, K; Hashimoto, Y; Karaki, F; Noguchi-Yachide, T; Ohgane, K | 1 |
1 other study(ies) available for ys 64 and Niemann-Pick Disease, Type C
| Article | Year |
|---|---|
Structure-activity relationships of oxysterol-derived pharmacological chaperones for Niemann-Pick type C1 protein.
Topics: Carrier Proteins; Dose-Response Relationship, Drug; Humans; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins; Molecular Structure; Mutation; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Sterols; Structure-Activity Relationship | 2014 |