Page last updated: 2024-11-04

stearic acid and Niemann-Pick Disease, Type C

stearic acid has been researched along with Niemann-Pick Disease, Type C in 1 studies

octadecanoic acid : A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.

Niemann-Pick Disease, Type C: An autosomal recessive lipid storage disorder that is characterized by accumulation of CHOLESTEROL and SPHINGOMYELINS in cells of the VISCERA and the CENTRAL NERVOUS SYSTEM. Type C (or C1) and type D are allelic disorders caused by mutation of the NPC1 gene, which encodes a protein that mediates intracellular cholesterol transport from LYSOSOMES. Clinical signs include hepatosplenomegaly and chronic neurological symptoms. Type D is a variant in people with a Nova Scotia ancestry.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Borbon, IA1
Hillman, Z1
Duran, E1
Kiela, PR1
Frautschy, SA1
Erickson, RP1

Other Studies

1 other study available for stearic acid and Niemann-Pick Disease, Type C

ArticleYear
Lack of efficacy of curcumin on neurodegeneration in the mouse model of Niemann-Pick C1.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:1

    Topics: Aging; Animals; Avoidance Learning; Carrier Proteins; Chromatography, High Pressure Liquid; Curcumin

2012