stearic acid has been researched along with Niemann-Pick Disease, Type C in 1 studies
octadecanoic acid : A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.
Niemann-Pick Disease, Type C: An autosomal recessive lipid storage disorder that is characterized by accumulation of CHOLESTEROL and SPHINGOMYELINS in cells of the VISCERA and the CENTRAL NERVOUS SYSTEM. Type C (or C1) and type D are allelic disorders caused by mutation of the NPC1 gene, which encodes a protein that mediates intracellular cholesterol transport from LYSOSOMES. Clinical signs include hepatosplenomegaly and chronic neurological symptoms. Type D is a variant in people with a Nova Scotia ancestry.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Borbon, IA | 1 |
| Hillman, Z | 1 |
| Duran, E | 1 |
| Kiela, PR | 1 |
| Frautschy, SA | 1 |
| Erickson, RP | 1 |
1 other study available for stearic acid and Niemann-Pick Disease, Type C
| Article | Year |
|---|---|
Lack of efficacy of curcumin on neurodegeneration in the mouse model of Niemann-Pick C1.
Topics: Aging; Animals; Avoidance Learning; Carrier Proteins; Chromatography, High Pressure Liquid; Curcumin | 2012 |