14,15-epoxy-5,8,11-eicosatrienoic acid has been researched along with Niemann-Pick Disease, Type C in 1 studies
14,15-epoxy-5,8,11-eicosatrienoic acid: RN given refers to cpd without isomeric designation
Niemann-Pick Disease, Type C: An autosomal recessive lipid storage disorder that is characterized by accumulation of CHOLESTEROL and SPHINGOMYELINS in cells of the VISCERA and the CENTRAL NERVOUS SYSTEM. Type C (or C1) and type D are allelic disorders caused by mutation of the NPC1 gene, which encodes a protein that mediates intracellular cholesterol transport from LYSOSOMES. Clinical signs include hepatosplenomegaly and chronic neurological symptoms. Type D is a variant in people with a Nova Scotia ancestry.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kang, I | 1 |
| Lee, BC | 1 |
| Lee, JY | 1 |
| Kim, JJ | 1 |
| Sung, EA | 1 |
| Lee, SE | 1 |
| Shin, N | 1 |
| Choi, SW | 1 |
| Seo, Y | 1 |
| Kim, HS | 1 |
| Kang, KS | 1 |
1 other study available for 14,15-epoxy-5,8,11-eicosatrienoic acid and Niemann-Pick Disease, Type C
| Article | Year |
|---|---|
Stem cell-secreted 14,15- epoxyeicosatrienoic acid rescues cholesterol homeostasis and autophagic flux in Niemann-Pick-type C disease.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Autophagy; Cells, Cultured; Cholesterol; Cytochrome P-450 CYP2 | 2018 |