fluorouracil has been researched along with Anal Fistula in 8 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Locally advanced anal cancer patients, especially with T4 disease and fistula, have a dismal prognosis." | 1.46 | Early closure of fistula using neo-adjuvant intra-arterial chemotherapy in locally advanced anal cancer. ( Allal, AS; Cacheux, W; Dietrich, PY; Fernandez, E; Ho, L; Koessler, T; Puppa, G; Ris, F; Roche, B; Roth, A; Zilli, T, 2017) |
| "We present a male patient with a perianal fistula of 30 years' duration that had been treated on several occasions." | 1.33 | [Mucinous adenocarcinoma on chronic perianal fistula treated by neoadjuvant chemoradiotherapy and laparoscopy-assisted abdominoperineal amputation]. ( Almendral, ML; Aranda, F; Echenique-Elizondo, M; Erro, JM; Ibáñez, J; Valenti, C, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cacheux, W | 1 |
| Koessler, T | 1 |
| Puppa, G | 1 |
| Fernandez, E | 1 |
| Ho, L | 1 |
| Dietrich, PY | 1 |
| Zilli, T | 1 |
| Allal, AS | 1 |
| Roche, B | 1 |
| Ris, F | 1 |
| Roth, A | 1 |
| Fukumoto, T | 1 |
| Hamada, J | 1 |
| Matsudaira, S | 1 |
| Yarita, A | 1 |
| Sakano, T | 1 |
| Kawarabayashi, N | 1 |
| Fukushima, J | 1 |
| Kamioka, N | 1 |
| Nagumo, H | 1 |
| Serizawa, M | 1 |
| Osaka, S | 1 |
| Hashimoto, Y | 1 |
| Ogasawara, A | 1 |
| Kim, CW | 1 |
| Kim, JH | 1 |
| Yu, CS | 1 |
| Shin, US | 1 |
| Park, JS | 1 |
| Jung, KY | 1 |
| Kim, TW | 1 |
| Yoon, SN | 1 |
| Lim, SB | 1 |
| Kim, JC | 1 |
| Ibáñez, J | 1 |
| Erro, JM | 1 |
| Aranda, F | 1 |
| Almendral, ML | 1 |
| Valenti, C | 1 |
| Echenique-Elizondo, M | 1 |
| Edelman, S | 1 |
| Johnstone, PA | 1 |
| Maeda, K | 1 |
| Hashimoto, M | 1 |
| Yamamoto, O | 1 |
| Koh, J | 1 |
| Sakai, S | 1 |
| Shiraishi, T | 1 |
| Chiba, Y | 1 |
| Hosoda, Y | 1 |
| Shirato, M | 1 |
| Seki, T | 1 |
| Fuhrman, GM | 1 |
| Ota, DM | 1 |
| Danjoux, CE | 1 |
| Catton, GE | 1 |
8 other studies available for fluorouracil and Anal Fistula
| Article | Year |
|---|---|
Early closure of fistula using neo-adjuvant intra-arterial chemotherapy in locally advanced anal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bleomycin; Chemoradioth | 2017 |
[A Case of Primary Anal Fistula Cancer with Extensive Intrapelvic Spreading That Was Successfully Treated with Bevacizumab plus mFOLFOX6].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Fluorouracil; Humans; Leucovorin; | 2019 |
Complications after sphincter-saving resection in rectal cancer patients according to whether chemoradiotherapy is performed before or after surgery.
Topics: Adenocarcinoma; Adult; Aged; Anal Canal; Anastomosis, Surgical; Antineoplastic Combined Chemotherapy | 2010 |
[Mucinous adenocarcinoma on chronic perianal fistula treated by neoadjuvant chemoradiotherapy and laparoscopy-assisted abdominoperineal amputation].
Topics: Adenocarcinoma, Mucinous; Antimetabolites, Antineoplastic; Anus Neoplasms; Chemotherapy, Adjuvant; C | 2006 |
Combined modality therapy for HIV-infected patients with squamous cell carcinoma of the anus: outcomes and toxicities.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cis | 2006 |
[A case of fistula-cancer response to arterial chemoembolization].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoembolization, T | 1994 |
Laparoscopic intestinal stomas.
Topics: Adenocarcinoma; Adult; Aged; Anus Neoplasms; Carcinoma, Squamous Cell; Colonic Diseases; Colostomy; | 1994 |
Delayed complications in colo-rectal carcinoma treated by combination radiotherapy and 5-fluorouracil--Eastern Cooperative Oncology Group (E.C.O.G.) pilot study.
Topics: Aged; Colonic Diseases; Colonic Neoplasms; Connective Tissue; Constriction, Pathologic; Female; Fluo | 1979 |