ciprofloxacin has been researched along with Anal Fistula in 17 studies
Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate, in a prospective, open-label study, the influence of antibiotics and azathioprine on the clinical outcome of perianal fistulas in patients with Crohn's disease." | 9.10 | Antibiotics and azathioprine for the treatment of perianal fistulas in Crohn's disease. ( Dejaco, C; Harrer, M; Miehsler, W; Reinisch, W; Vogelsang, H; Waldhoer, T, 2003) |
| "Ciprofloxacin was well tolerated." | 6.74 | Ciprofloxacin or metronidazole for the treatment of perianal fistulas in patients with Crohn's disease: a randomized, double-blind, placebo-controlled pilot study. ( Bernstein, CN; Bitton, A; Cockeram, A; Feagan, BG; Mahadevan, U; Sandborn, WJ; Thia, KT; Wong, C, 2009) |
| "Ciprofloxacin is effective in perianal Crohn's disease but after treatment discontinuation symptoms reoccur." | 6.71 | Clinical and endosonographic effect of ciprofloxacin on the treatment of perianal fistulae in Crohn's disease with infliximab: a double-blind placebo-controlled study. ( Drapers, JA; Felt-Bersma, RJ; Hansen, BE; Kuipers, EJ; van der Woude, CJ; van Tilburg, AJ; West, RL, 2004) |
| "In this study we aimed to determine the microorganisms found in perianal fistulas in Crohn's disease and whether treatment with ciprofloxacin affects these microorganisms." | 5.11 | Perianal fistulas in Crohn's disease are predominantly colonized by skin flora: implications for antibiotic treatment? ( Boelens, HA; Endtz, HP; Hansen, BE; Kuipers, EJ; Kusters, JG; Ouwedijk, M; Van der Woude, CJ; West, RL, 2005) |
| "To evaluate, in a prospective, open-label study, the influence of antibiotics and azathioprine on the clinical outcome of perianal fistulas in patients with Crohn's disease." | 5.10 | Antibiotics and azathioprine for the treatment of perianal fistulas in Crohn's disease. ( Dejaco, C; Harrer, M; Miehsler, W; Reinisch, W; Vogelsang, H; Waldhoer, T, 2003) |
| "Fifty-two patients (median age 36 yr) with draining perianal fistulas were treated with ciprofloxacin (N = 49) or metronidazole (N = 3) for a median duration of 7 wk." | 3.74 | NOD2/CARD15 gene variants are linked to failure of antibiotic treatment in perianal fistulating Crohn's disease. ( Angelberger, S; Dejaco, C; Lichtenberger, C; Miehsler, W; Reinisch, W; Schaeffeler, E; Schwab, M; Teml, A; Vogelsang, H; Waldhoer, T; Wehkamp, J, 2008) |
| "Ciprofloxacin was well tolerated." | 2.74 | Ciprofloxacin or metronidazole for the treatment of perianal fistulas in patients with Crohn's disease: a randomized, double-blind, placebo-controlled pilot study. ( Bernstein, CN; Bitton, A; Cockeram, A; Feagan, BG; Mahadevan, U; Sandborn, WJ; Thia, KT; Wong, C, 2009) |
| "Ciprofloxacin is effective in perianal Crohn's disease but after treatment discontinuation symptoms reoccur." | 2.71 | Clinical and endosonographic effect of ciprofloxacin on the treatment of perianal fistulae in Crohn's disease with infliximab: a double-blind placebo-controlled study. ( Drapers, JA; Felt-Bersma, RJ; Hansen, BE; Kuipers, EJ; van der Woude, CJ; van Tilburg, AJ; West, RL, 2004) |
| " Moreover, long-term use of glucocorticosteroids is associated with serious and sometimes irreversible side effects." | 2.42 | An historical overview of the treatment of Crohn's disease: why do we need biological therapies? ( Rutgeerts, PJ, 2004) |
| "Stool samples and rectal and perianal fistula swabs were collected." | 1.72 | A Microbial Signature for Paediatric Perianal Crohn's Disease. ( Albenberg, L; Baldassano, RN; Bittinger, K; Breton, J; Devas, N; Hwang, R; Kachelries, K; Mattei, P; Rowley, S; Tanes, C; Tu, V; Wu, GD, 2022) |
| "It is extremely rare that the urinary bladder stones cause vesicorectal fistulas." | 1.40 | Is vesicolithotomy with bladder wash the answer for rectovesical fistula secondary to neglected vesical stone? Complicated presentation but simple management. ( Elnaim, AK; Mohamed, MM, 2014) |
| "Genital fistulas are a significant problem in female Crohn's disease patients." | 1.38 | Genital fistulas in female Crohn's disease patients.: clinical characteristics and response to therapy. ( Bermejo, F; de la Poza, G; Gisbert, JP; López-Sanroman, A; Marín-Jimenez, I; Muriel, A; Opio, V; Taxonera, C, 2012) |
| "Appropriate treatment of perianal fistulas in Crohn's disease (CD) involves accurate anatomic evaluation." | 1.38 | Endoscopic ultrasound for perianal Crohn's disease: disease and fistula characteristics, and impact on therapy. ( Assulin, Y; Beer-Gabel, M; Chowers, Y; Lahat, A, 2012) |
| "Presence/absence of history of perianal fistula was recorded." | 1.37 | CARD15 mutations and perianal fistulating Crohn's disease: correlation and predictive value of antibiotic response. ( Andrade, P; Donato, MM; Ferreira, M; Freire, P; Portela, F; Sofia, C, 2011) |
| "Recto-urethral fistulas due to Crohn's disease are very uncommon." | 1.35 | [Urethral fistula due to Crohn's disease: case report of successful conservative management]. ( Borovicka, J; Engeler, DS; Hetzer, FH; Meyer, D; Schmid, HP; Schwab, C, 2008) |
| "Biopsy examination showed malakoplakia with characteristic Michaelis-Gutmann bodies." | 1.33 | Rectal malakoplakia presenting as a mass and fistulous tract in a renal transplant patient. ( Abbas, Z; Mubarak, M; Yousif, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (58.82) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Breton, J | 1 |
| Tanes, C | 1 |
| Tu, V | 1 |
| Albenberg, L | 1 |
| Rowley, S | 1 |
| Devas, N | 1 |
| Hwang, R | 1 |
| Kachelries, K | 1 |
| Wu, GD | 1 |
| Baldassano, RN | 1 |
| Bittinger, K | 1 |
| Mattei, P | 1 |
| Ghahramani, L | 1 |
| Minaie, MR | 1 |
| Arasteh, P | 1 |
| Hosseini, SV | 1 |
| Izadpanah, A | 1 |
| Bananzadeh, AM | 1 |
| Ahmadbeigi, M | 1 |
| Hooshanginejad, Z | 1 |
| Dewint, P | 1 |
| Hansen, BE | 3 |
| Verhey, E | 1 |
| Oldenburg, B | 1 |
| Hommes, DW | 1 |
| Pierik, M | 1 |
| Ponsioen, CI | 1 |
| van Dullemen, HM | 1 |
| Russel, M | 1 |
| van Bodegraven, AA | 1 |
| van der Woude, CJ | 3 |
| Elnaim, AK | 1 |
| Mohamed, MM | 1 |
| Thia, KT | 1 |
| Mahadevan, U | 1 |
| Feagan, BG | 1 |
| Wong, C | 1 |
| Cockeram, A | 1 |
| Bitton, A | 1 |
| Bernstein, CN | 1 |
| Sandborn, WJ | 1 |
| Freire, P | 1 |
| Portela, F | 1 |
| Donato, MM | 1 |
| Ferreira, M | 1 |
| Andrade, P | 1 |
| Sofia, C | 1 |
| de la Poza, G | 1 |
| López-Sanroman, A | 1 |
| Taxonera, C | 1 |
| Marín-Jimenez, I | 1 |
| Gisbert, JP | 1 |
| Bermejo, F | 1 |
| Opio, V | 1 |
| Muriel, A | 1 |
| Lahat, A | 1 |
| Assulin, Y | 1 |
| Beer-Gabel, M | 1 |
| Chowers, Y | 1 |
| Dejaco, C | 2 |
| Harrer, M | 1 |
| Waldhoer, T | 2 |
| Miehsler, W | 2 |
| Vogelsang, H | 2 |
| Reinisch, W | 2 |
| Rutgeerts, PJ | 1 |
| West, RL | 2 |
| Felt-Bersma, RJ | 1 |
| van Tilburg, AJ | 1 |
| Drapers, JA | 1 |
| Kuipers, EJ | 2 |
| Endtz, HP | 1 |
| Ouwedijk, M | 1 |
| Boelens, HA | 1 |
| Kusters, JG | 1 |
| Dignass, AU | 1 |
| Yousif, M | 1 |
| Abbas, Z | 1 |
| Mubarak, M | 1 |
| Atienza, P | 1 |
| Angelberger, S | 1 |
| Wehkamp, J | 1 |
| Lichtenberger, C | 1 |
| Schaeffeler, E | 1 |
| Schwab, M | 1 |
| Teml, A | 1 |
| Schwab, C | 1 |
| Meyer, D | 1 |
| Hetzer, FH | 1 |
| Borovicka, J | 1 |
| Schmid, HP | 1 |
| Engeler, DS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Adalimumab for the Treatment of Perianal Fistulas in Crohn's Disease More Effective Alone or Combined to Ciprofloxacin[NCT00736983] | Phase 3 | 76 participants (Actual) | Interventional | 2008-09-30 | Completed | ||
| A Prospective Longitudinal Study on the Effect of Tight Control Management on Perianal Crohn's Disease[NCT03861689] | 40 participants (Anticipated) | Interventional | 2019-07-01 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for ciprofloxacin and Anal Fistula
| Article | Year |
|---|---|
An historical overview of the treatment of Crohn's disease: why do we need biological therapies?
Topics: Anti-Infective Agents; Biological Therapy; Ciprofloxacin; Crohn Disease; Glucocorticoids; Humans; Im | 2004 |
[Refractory perineal fistulas in Crohn's disease].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal; Ciprofloxacin; Crohn Diseas | 2007 |
6 trials available for ciprofloxacin and Anal Fistula
| Article | Year |
|---|---|
Antibiotic therapy for prevention of fistula in-ano after incision and drainage of simple perianal abscess: A randomized single blind clinical trial.
Topics: Abscess; Anti-Bacterial Agents; Antibiotic Prophylaxis; Anus Diseases; Ciprofloxacin; Drainage; Huma | 2017 |
Adalimumab combined with ciprofloxacin is superior to adalimumab monotherapy in perianal fistula closure in Crohn's disease: a randomised, double-blind, placebo controlled trial (ADAFI).
Topics: Adalimumab; Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibodies, Mo | 2014 |
Ciprofloxacin or metronidazole for the treatment of perianal fistulas in patients with Crohn's disease: a randomized, double-blind, placebo-controlled pilot study.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Crohn Disease; Double-Blind Method; Female; Humans; Mal | 2009 |
Antibiotics and azathioprine for the treatment of perianal fistulas in Crohn's disease.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Anti-Bacterial Agents; Anus Diseases; Azathioprine; | 2003 |
Clinical and endosonographic effect of ciprofloxacin on the treatment of perianal fistulae in Crohn's disease with infliximab: a double-blind placebo-controlled study.
Topics: Adolescent; Adult; Anti-Infective Agents; Antibodies, Monoclonal; Ciprofloxacin; Crohn Disease; Doub | 2004 |
Perianal fistulas in Crohn's disease are predominantly colonized by skin flora: implications for antibiotic treatment?
Topics: Adult; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Corynebacterium Infections; Crohn | 2005 |
9 other studies available for ciprofloxacin and Anal Fistula
| Article | Year |
|---|---|
A Microbial Signature for Paediatric Perianal Crohn's Disease.
Topics: Ciprofloxacin; Crohn Disease; Ecosystem; Humans; Rectal Fistula; Treatment Outcome | 2022 |
Is vesicolithotomy with bladder wash the answer for rectovesical fistula secondary to neglected vesical stone? Complicated presentation but simple management.
Topics: Adult; Anti-Bacterial Agents; Ciprofloxacin; Humans; Male; Rectal Fistula; Recurrence; Urinary Bladd | 2014 |
CARD15 mutations and perianal fistulating Crohn's disease: correlation and predictive value of antibiotic response.
Topics: Adult; Anti-Bacterial Agents; Ciprofloxacin; Crohn Disease; Drug Therapy, Combination; Female; Genet | 2011 |
Genital fistulas in female Crohn's disease patients.: clinical characteristics and response to therapy.
Topics: Adalimumab; Adolescent; Adult; Age Factors; Anti-Infective Agents; Anti-Inflammatory Agents; Antibod | 2012 |
Endoscopic ultrasound for perianal Crohn's disease: disease and fistula characteristics, and impact on therapy.
Topics: Abscess; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Infective Agents; Anti-Inflammatory | 2012 |
[Management of perianal fistulizing Crohn's disease: a conservative approach].
Topics: Anti-Infective Agents; Ciprofloxacin; Combined Modality Therapy; Crohn Disease; Fecal Incontinence; | 2005 |
Rectal malakoplakia presenting as a mass and fistulous tract in a renal transplant patient.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Fissure in Ano; Fistula; Humans; Kidney Transplantation | 2006 |
NOD2/CARD15 gene variants are linked to failure of antibiotic treatment in perianal fistulating Crohn's disease.
Topics: Adult; Alleles; Anti-Infective Agents; beta-Defensins; Ciprofloxacin; Crohn Disease; Female; Genetic | 2008 |
[Urethral fistula due to Crohn's disease: case report of successful conservative management].
Topics: Azathioprine; Ciprofloxacin; Crohn Disease; Cystoscopy; Cystostomy; Diagnosis, Differential; Drug Th | 2008 |