Page last updated: 2024-11-05

thalidomide and Anal Fistula

thalidomide has been researched along with Anal Fistula in 2 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Research Excerpts

ExcerptRelevanceReference
"Fistulas are common in patients with Crohn's disease and, when associated with inflammatory disease and established for several weeks, tend to be chronic."2.41Management of fistulas in patients with Crohn's disease: antibiotic to antibody. ( Paré, P, 2001)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Paré, P1
Schärli, AF1

Reviews

1 review available for thalidomide and Anal Fistula

ArticleYear
Management of fistulas in patients with Crohn's disease: antibiotic to antibody.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2001, Volume: 15, Issue:11

    Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; Azathioprine; Colonic Diseases; Crohn Disease; Cyclos

2001

Other Studies

1 other study available for thalidomide and Anal Fistula

ArticleYear
[Congenital abnormalities of rectum and anus. Diagnosis, physiology and therapy].
    Aktuelle Probleme in der Chirurgie, 1971, Volume: 15

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anal Canal; Anus, Imperforate; Congenital Abno

1971