Page last updated: 2024-08-05 12:45:13
quassinoid
Members of the class of triterpenoid, mostly isolated as bitter principles of the Simaroubaceae family. They are chemically regarded as degraded triterpenes and can be categorized into groups with C18, C19, C20, C22 and C25 skeletons.
ChEBI ID: 72485
Members (4)
| Member | Definition | Role |
|---|
| bruceine a | | Bruceine A |
| eurycomanone | A quassinoid isolated from Eurycoma longifolia and has been shown to exhibit antineoplastic and antimalarial activties. | eurycomanone |
| glaucarubinone | A quassinoid with formula C25H34O10. It is a natural product isolated from several plant species and exhibits anti-cancer and anti-malarial properties. | glaucarubinone |
| simalikalactone D | A quassinoid isolated from Quassia amara and Quassia africana. It has been shown to exhibit antimalarial, cytotoxic and antiviral activities. | simalikalactone D |
Research
Studies (30)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|
| pre-1990 | 2 (6.67) | 18.7374 |
| 1990's | 2 (6.67) | 18.2507 |
| 2000's | 10 (33.33) | 29.6817 |
| 2010's | 9 (30.00) | 24.3611 |
| 2020's | 7 (23.33) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|
| Trials | 1 (2.78%) | 5.53% |
| Reviews | 2 (5.56%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 33 (91.67%) | 84.16% |