Compounds > pyrethrin i
Page last updated: 2024-12-10

pyrethrin i

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

pyrethrin I: a naturally occurring pyrethrins; active constituent of pyrethrum flowers; 4-hydroxy-3-methyl-2-(2,4-pentadienyl)- 2-cyclopenten-1-one ester of 2,2-dimethyl-3- (2-methylpropenyl)cyclopropanecarboxylic acid; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID5281045
CHEBI ID27815
SCHEMBL ID26537
MeSH IDM0053543

Synonyms (45)

Synonym
brn 2004306
pyrethrin i [bsi:iso]
2-methyl-4-oxo-3-(2,4-pentadienyl)-2-cyclopenten-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropane carboxylate
einecs 204-455-8
piretrina 1 [portuguese]
cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, 2-methyl-4-oxo-3-(2,4-pentadienyl)-2-cyclopenten-1-yl ester, (1theta-(1alpha(s(z)),3beta))-
2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylic acid 2-methyl-4-oxo-3-(2,4-pentadienyl)-2-cycloenten-1-yl ester
pyrethrine i [iso-french]
pyrethrolone, chrysanthemum monocarboxylic acid ester
cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, 2-methyl-4-oxo-3-(2,4-pentadienyl)-2-cyclopenten-1-yl ester, (1r-(1alpha(s*(z)),3beta))-
cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methylpropenyl)-, ester with 4-hydroxy-3-methyl-2-(2,4-pentadienyl)-2-cyclopenten-1-one
hsdb 6302
2-methyl-4-oxo-3-(penta-2,4-dienyl)cyclopent-2-enyl (1r-(1alpha(s*(z)),3beta))-chrysanthemate
caswell no. 715
epa pesticide chemical code 069001
cyclopropaneacrylic acid, 2,2-dimethyl-3-(2-methylpropenyl)-, ester with 4-hydroxy-3-methyl-2-(2,4-pentadienyl)-2-cyclopenten-1-one
(+)-pyrethronyl (+)-trans-chrysanthemate
pyrethrin i
121-21-1
C07594
(1s)-2-methyl-4-oxo-3-[(2z)-penta-2,4-dien-1-yl]cyclopent-2-en-1-yl (1r,3r)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylate
chrysanthemum monocarboxylic acid pyrethrolone ester
CHEBI:27815
bubil (tn)
D08452
[(1s)-2-methyl-4-oxo-3-[(2z)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1r,3r)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate
[(1s)-2-methyl-4-oxo-3-[(2z)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1r,3r)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate
t018i9eqol ,
unii-t018i9eqol
3-09-00-00215 (beilstein handbook reference)
pyrethrine i
piretrina 1
cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, (1s)-2-methyl-4-oxo-3-(2z)-2,4-pentadienyl-2-cyclopenten-1-yl ester, (1r,3r)-
(1s)-2-methyl-4-oxo-3-(2z)-2,4-pentadienylcyclopenten-1-yl (1r,3r)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate
(z)-(s)-2-methyl-4-oxo-3-(penta-2,4-dienyl)cyclopent-2-enyl (+)-trans-chrysanthemate
(z)-(s)-2-methyl-4-oxo-3-(penta-2,4-dienyl)cyclopent-2-enyl (1r,3r)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate
pyrethrin i [who-dd]
pyrethrin i [hsdb]
pyrethrin i [iso]
pyrethrin i [mi]
SCHEMBL26537
DTXSID4034499
pyrethrin 1 100 microg/ml in cyclohexane
Q7263468
1ST20457
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
pyrethrinsThe active insecticidal constituents of Chrysanthemum cinerariifolium flowers.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (1)

PathwayProteinsCompounds
pyrethrin I biosynthesis18
pyrethrin I biosynthesis110

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's2 (15.38)18.2507
2000's5 (38.46)29.6817
2010's5 (38.46)24.3611
2020's1 (7.69)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 22.60

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index22.60 (24.57)
Research Supply Index2.71 (2.92)
Research Growth Index4.78 (4.65)
Search Engine Demand Index31.58 (26.88)
Search Engine Supply Index3.00 (0.95)

This Compound (22.60)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies1 (7.14%)4.05%
Observational0 (0.00%)0.25%
Other13 (92.86%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
1-anilino-8-naphthalenesulfonate
1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd. 8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.		2.0710aminonaphthalene;
naphthalenesulfonic acid		fluorescent probe
chlorpyrifos
Chlorpyrifos: An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.. chlorpyrifos : An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.		1.9910chloropyridine;
organic thiophosphate		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic
chrysanthemic acid
chrysanthemic acid: occurs as esters in pyrethrum flowers; RN given refers to cpd without isomeric designation; structure. chrysanthemic acid : A monocarboxylic acid that is cyclopropanecarboxylic acid substituted by two methyl groups at position 2 and a 2-methylprop-1-en-1-yl group at position 3.		2.7330cyclopropanes;
monocarboxylic acid		plant metabolite
cypermethrin
cypermethrin : A carboxylic ester resulting from the formal condensation between 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid and the alcoholic hydroxy group of hydroxy(3-phenoxyphenyl)acetonitrile.. zeta-cypermethrin : A diastereoisomeric mixture comprising the isomeric pair (1R)-cis-(alphaS)- and (1S)-trans-(alphaR)-cypermethrin together with the isomeric pair (1S)-cis-(alphaS)- and (1S)-trans-(alphaS)-cypermethrin where the ratio between the isomeric pairs lies in the range 45:55 to 55:45.		2.0510aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound		agrochemical;
molluscicide;
pyrethroid ester acaricide;
pyrethroid ester insecticide
piperonyl butoxide
[no description available]		2.0310benzodioxolespesticide synergist
silver nitrate
Silver Nitrate: A silver salt with powerful germicidal activity. It has been used topically to prevent OPHTHALMIA NEONATORUM.		2.2510inorganic nitrate salt;
silver salt		astringent
decamethrin
decamethrin: pyrethroid insecticide; RN given refers to cpd without isomeric designation; structure		2.4920aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organobromine compound		agrochemical;
antifeedant;
calcium channel agonist;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
pyrethroid ester insecticide
pyriproxyfen
pyriproxyfen: an insect growth regulator; RN given refers to cpd without isomeric designation. pyriproxyfen : An aromatic ether that consists of propylene glycol having a 2-pyridyl group at the O-1 position and a 4-phenoxyphenyl group at the O-3 position.		2.1510aromatic ether;
pyridines		juvenile hormone mimic
chrysanthemol
chrysanthemol: a trans-eudesmane type sesquiterpene from flowers of Chrysanthemum indicum L.; structure given in first source		2.2110cyclopropanes;
homoallylic alcohol;
monoterpenoid;
primary alcohol
cinerin a
cinerin A: isolated from Pleurothyrium cinereum; structure in first source		2.4620
pyrethrins
[no description available]		3.99130
ConditionIndicatedRelationship StrengthStudiesTrials
Mydriasis
Dilation of pupils to greater than 6 mm combined with failure of the pupils to constrict when stimulated with light. This condition may occur due to injury of the pupillary fibers in the oculomotor nerve, in acute angle-closure glaucoma, and in ADIE SYNDROME.		02.0110