Blue Tongue

A reovirus infection, chiefly of sheep, characterized by a swollen blue tongue, catarrhal inflammation of upper respiratory and gastrointestinal tracts, and often by inflammation of sensitive laminae of the feet and coronet.

Synonym
Bluetongue
Blue Tongue

Excerpt	Reference
"Bluetongue is an insect-transmitted disease of sheep and wild ruminants that is caused by bluetongue virus (BTV)."	( Bonneau, KR; DeMaula, CD; Leutenegger, CM; MacLachlan, NJ, 2002)
"Bluetongue is a serious hemorrhagic disease of sheep, cattle and other ruminants causing economic losses worldwide."	( Nanjundappa, RH; Pandey, AB; Singh, KP; Singh, RP; Umeshappa, CS, 2010)
"Bluetongue is an economically important viral disease of small ruminants."	( Deb, R; Kantaraja, C; Kumar, A; Kumar, S; Saxena, VK; Shrivastava, S, 2012)
"Bluetongue is a disease of major economic concern in Europe."	( Baldet, T; Barceló, C; Calvete, C; Del Río, R; Lucientes, J; Miranda, MA; Venail, R, 2014)
"Bluetongue is endemic in India and has been reported from most Indian states."	( Batra, K; Chanda, MM; Hegde, NR; Hemadri, D; Krishnajyothi, Y; Kumar, V; Maan, NS; Maan, S; Mertens, PPC; Putty, K; Rahman, H; Rao, PP; Reddy, GH; Reddy, YN; Reddy, YV; Shivachandra, SB; Singh, KP, 2017)
"Bluetongue is a non-contagious viral disease causing significant economic losses throughout the world."	( Kar, S; Mazumdar, A; Mondal, B; Pal, A, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	47 (31.97)	23.3326
1990's	10 (6.80)	12.5806
2000's	21 (14.29)	18.1394
2010's	54 (36.73)	28.8240
2020's	15 (10.20)	9.53

Drug	Relationship Strength	Studies
methane	low	1
formaldehyde	low	1
glycerol	low	1
histamine	low	2
urea	low	1
menthol	low	1
bendiocarb	low	1
propiolactone	low	1
chlorpyrifos	low	1
cimetidine	low	2
cypermethrin	low	2
erythrosine	low	1
fenthion	low	1
fenvalerate	low	2
malathion	low	1
deet	low	1
temefos	low	1
thymidine	low	2
floxuridine	low	1
piperonyl butoxide	low	1
sucrose	low	3
adenosine diphosphate	low	1
uridine	low	7
bromodeoxyuridine	low	1
edetic acid	low	1
leucine	low	2
phenylalanine	low	1
cycloheximide	low	1
chloroform	low	2
phencyclidine	low	1
terpin	low	1
thiophenes	low	1
aziridine	low	2
deoxyuridine	low	1
fluorescein-5-isothiocyanate	low	1
carbonates	low	1
manganese	low	1
gold	low	2
levamisole	low	2
permethrin	low	3
decamethrin	low	7
tebuconazole	low	1
fibrinogen	low	1
thromboxanes	low	2
biotin	low	3
mevalonic acid	low	1
inositol 3-phosphate	low	1
abacavir	low	1
dactinomycin	low	2
u 0126	low	1
freedom	low	1
sodium dodecyl sulfate	low	1
alpha-chymotrypsin	low	1
bilirubin	low	1
thromboxane a2	low	1
cyhalothrin	low	2
thromboxane b2	low	1
phenylephrine hydrochloride	low	2
lysophosphatidylcholines	low	1
aluminum	low	1
oxalates	low	1
(3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid	low	1
beta-escin	low	1
dextrothyroxine	low	1
sepharose	low	1
clove	low	1
cytochrome c-t	low	1
tannins	low	1
oligonucleotides	low	1
interleukin-8	low	1
sybr green i	low	1
pyrethrins	low	13
agar	low	2
apyrase	low	1
exudates	low	1
phosphorus radioisotopes	low	2

Protein Targets (519)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Cytochrome P450 2C9	0	2	0	2
Luciferase	8	0	0	8
cytochrome P450 family 3 subfamily A polypeptide 4	8	0	0	8
cytochrome P450 2D6	6	0	0	6
euchromatic histone-lysine N-methyltransferase 2	15	0	0	15
peripheral myelin protein 22	12	0	0	12
Albumin	0	0	1	1
ATP-dependent translocase ABCB1	0	2	0	3
Replicase polyprotein 1ab	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Reverse transcriptase/RNaseH	0	2	1	3
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
regulator of G-protein signaling 4	3	0	0	3
HPr kinase/phosphorylase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-alpha	0	1	1	3
Heat shock protein HSP 90-beta	0	1	1	3
2-dehydropantoate 2-reductase	0	1	1	2
Heat shock 70 kDa protein 1A	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Heat shock cognate 71 kDa protein	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Endoplasmin	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	3	0	3
Mu-type opioid receptor	0	0	1	1
Delta-type opioid receptor	0	0	1	1
Kappa-type opioid receptor	0	0	1	1
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
Phosphatidylinositol 4-kinase alpha	0	2	0	2
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	3	0	0	3
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	2
P2Y purinoceptor 11	0	0	1	1
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	2
P2Y purinoceptor 12	0	0	1	1
Sensor protein kinase WalK	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	2	0	2
P2X purinoceptor 2	0	0	1	1
acetylcholinesterase	6	0	0	6
TDP1 protein	12	0	0	12
AR protein	27	0	0	27
aldehyde dehydrogenase 1 family, member A1	15	0	0	15
glucocorticoid receptor [Homo sapiens]	14	0	0	14
retinoic acid nuclear receptor alpha variant 1	19	0	0	19
retinoid X nuclear receptor alpha	18	0	0	18
pregnane X nuclear receptor	18	0	0	18
estrogen nuclear receptor alpha	28	0	0	28
peroxisome proliferator-activated receptor delta	11	0	0	11
Histone H2A.x	11	0	0	11
heat shock protein beta-1	8	0	0	8
serine/threonine-protein kinase PLK1	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 1	23	0	0	23
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	9	0	0	9
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
Chain A, HADH2 protein	5	0	0	5
Chain B, HADH2 protein	5	0	0	5
Chain A, 2-oxoglutarate Oxygenase	2	0	0	2
Chain A, Cruzipain	4	0	0	4
phosphopantetheinyl transferase	9	0	0	9
USP1 protein, partial	7	0	0	7
Microtubule-associated protein tau	6	0	0	6
vitamin D3 receptor isoform VDRA	10	0	0	10
DNA polymerase kappa isoform 1	5	0	0	5
caspase-1 isoform alpha precursor	2	0	0	2
lamin isoform A-delta10	12	0	0	12
Caspase-7	2	0	0	2
Solute carrier organic anion transporter family member 1B3	0	2	0	3
Solute carrier organic anion transporter family member 1B1	0	2	0	3
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	5	0	0	5
RAR-related orphan receptor gamma	20	0	0	20
apical membrane antigen 1, AMA1	3	0	0	3
nonstructural protein 1	0	1	0	1
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
interleukin 8	7	0	0	7
pregnane X receptor	8	0	0	8
ATAD5 protein, partial	3	0	0	3
nuclear receptor subfamily 1, group I, member 3	18	0	0	18
progesterone receptor	16	0	0	16
estrogen-related nuclear receptor alpha	23	0	0	23
bromodomain adjacent to zinc finger domain 2B	5	0	0	5
arylsulfatase A	2	0	0	2
IDH1	4	0	0	4
nuclear receptor subfamily 1, group I, member 2	1	0	0	1
cellular tumor antigen p53 isoform a	3	0	0	3
Nuclear hormone receptor family member daf-12	0	0	1	1
chromobox protein homolog 1	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 2	4	0	0	4
thyroid hormone receptor beta isoform 2	18	0	0	18
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
oxysterols receptor LXR-beta isoform 1	0	0	1	1
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
geminin	13	0	0	13
survival motor neuron protein isoform d	6	0	0	6
muscarinic acetylcholine receptor M1	2	0	0	2
Voltage-dependent calcium channel gamma-2 subunit	11	0	0	11
Thymidine kinase, cytosolic	0	3	0	6
Glutamate receptor 2	11	0	0	11
Thymidine phosphorylase	0	0	0	4
Thymidylate kinase	0	2	0	2
Nuclear receptor ROR-gamma	9	0	0	9
Spike glycoprotein	7	0	1	8
Thymidine kinase	0	0	0	3
Thymidylate kinase	0	2	0	2
ATPase family AAA domain-containing protein 5	3	0	0	3
Ataxin-2	3	0	0	3
Carbonic anhydrase 1	0	1	0	3
Carbonic anhydrase 2	0	2	1	6
Carbonic anhydrase 4	0	1	0	3
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase 15	0	1	0	3
hypoxia-inducible factor 1 alpha subunit	11	0	0	11
GLI family zinc finger 3	15	0	0	15
vitamin D (1,25- dihydroxyvitamin D3) receptor	11	0	0	11
v-jun sarcoma virus 17 oncogene homolog (avian)	15	0	0	15
Cellular tumor antigen p53	21	0	0	21
15-lipoxygenase, partial	3	0	0	3
PINK1	1	0	0	1
thyroid stimulating hormone receptor	7	0	0	7
estrogen receptor 2 (ER beta)	7	0	0	7
Parkin	1	0	0	1
peroxisome proliferator activated receptor gamma	13	0	0	13
aryl hydrocarbon receptor	11	0	0	11
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	10	0	0	10
thyroid stimulating hormone receptor	11	0	0	11
activating transcription factor 6	12	0	0	12
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	10	0	0	10
Caspase-7	2	0	0	2
serine-protein kinase ATM isoform a	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
prostaglandin E2 receptor EP2 subtype	0	0	0	1
thyroid hormone receptor beta isoform a	13	0	0	13
potassium voltage-gated channel subfamily H member 2 isoform d	6	0	0	6
caspase-3	2	0	0	2
mitogen-activated protein kinase 1	3	0	0	3
lethal(3)malignant brain tumor-like protein 1 isoform I	3	0	0	3
cytochrome P450 3A4 isoform 1	8	0	0	8
histone acetyltransferase KAT2A isoform 1	6	0	0	6
lethal factor (plasmid)	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	8	0	0	8
Acetylcholinesterase	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	8	0	0	8
Gamma-aminobutyric acid receptor subunit delta	8	0	0	8
Gamma-aminobutyric acid receptor subunit gamma-2	8	0	0	8
Gamma-aminobutyric acid receptor subunit alpha-5	8	0	0	8
Gamma-aminobutyric acid receptor subunit alpha-3	8	0	0	8
Gamma-aminobutyric acid receptor subunit gamma-1	8	0	0	8
Gamma-aminobutyric acid receptor subunit alpha-2	8	0	0	8
Gamma-aminobutyric acid receptor subunit alpha-4	8	0	0	8
Gamma-aminobutyric acid receptor subunit gamma-3	8	0	0	8
Gamma-aminobutyric acid receptor subunit alpha-6	8	0	0	8
Gamma-aminobutyric acid receptor subunit alpha-1	8	0	0	8
Gamma-aminobutyric acid receptor subunit beta-3	8	0	0	8
Gamma-aminobutyric acid receptor subunit beta-2	8	0	0	8
Carboxylic ester hydrolase	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
GABA theta subunit	8	0	0	8
Gamma-aminobutyric acid receptor subunit epsilon	8	0	0	8
ORF73	0	0	1	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	11	0	0	11
G	7	0	0	7
alpha-galactosidase	2	0	0	2
cytochrome P450 2C19 precursor	1	0	0	1
M-phase phosphoprotein 8	2	0	0	2
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	2	0	4
Solute carrier family 22 member 1	0	2	0	3
ATP-binding cassette sub-family C member 3	0	1	0	1
Multidrug resistance-associated protein 4	0	1	0	1
Solute carrier family 22 member 6	0	2	0	2
Solute carrier family 22 member 2	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Bile salt export pump	0	4	0	4
Interferon beta	9	0	0	9
HLA class I histocompatibility antigen, B alpha chain	7	0	0	7
ATP-dependent translocase ABCB1	0	1	0	1
Cytochrome P450 3A4	0	1	0	1
Cytochrome P450 2D6	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Histamine H2 receptor	0	3	2	5
Histamine H1 receptor	0	1	3	4
Histamine H2 receptor	1	2	2	5
Potassium-transporting ATPase subunit beta	0	1	0	1
Cytochrome P450 2J2	0	1	0	1
Aldehyde oxidase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 1	0	3	0	4
Multidrug and toxin extrusion protein 2	0	1	0	1
Solute carrier family 22 member 8	0	2	0	3
Inositol hexakisphosphate kinase 1	7	0	0	7
Canalicular multispecific organic anion transporter 1	0	1	0	1
Multidrug and toxin extrusion protein 1	0	1	0	1
Histamine H4 receptor	0	2	2	4
Solute carrier family 22 member 11	0	1	0	1
Solute carrier family 22 member 2	0	3	0	4
Solute carrier family 22 member 4	0	1	0	1
Solute carrier family 22 member 8	0	2	0	2
cytochrome P450 2C9, partial	7	0	0	7
ATP-dependent phosphofructokinase	4	0	0	4
glp-1 receptor, partial	2	0	0	2
Fumarate hydratase	2	0	0	2
PPM1D protein	1	0	0	1
Smad3	1	0	0	1
EWS/FLI fusion protein	2	0	0	2
farnesoid X nuclear receptor	14	0	0	14
polyprotein	2	0	0	2
67.9K protein	2	0	0	2
P53	1	0	0	1
RPL19A	0	0	1	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	4	0	0	4
ras-related protein Rab-9A	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
nuclear receptor ROR-gamma isoform 1	3	0	0	3
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
COUP transcription factor 2 isoform a	0	1	0	1
Transmembrane protease serine 2	0	0	1	1
Glucose transporter	0	1	0	1
Hexose transporter 1	0	1	0	1
Procathepsin L	0	0	1	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 1	0	1	0	1
Alpha-synuclein	1	0	0	1
Eukaryotic initiation factor 4A-I	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	0	2
Peptidyl-prolyl cis-trans isomerase FKBP3	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP4	0	1	0	1
TAR DNA-binding protein 43	1	0	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	0	1
Endothelial PAS domain-containing protein 1	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP14	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	0	1	0	1
heat shock protein 90, putative	0	0	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
Chain A, Ferritin light chain	4	0	0	4
caspase 7, apoptosis-related cysteine protease	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	2	0	0	2
caspase-3	2	0	0	2
RAD51	0	1	0	1
Bloom syndrome protein isoform 1	4	0	0	4
huntingtin isoform 2	1	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	1	0	1
Discoidin domain-containing receptor 2	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
Chain A, Odorant binding protein	0	0	1	1
Chain B, Odorant binding protein	0	0	1	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
Chain A, Dutpase	0	0	1	1
Chain A, Dutpase	0	0	1	1
Chain B, Dutpase	0	0	1	1
Chain A, Dutpase	0	0	1	1
Chain B, Dutpase	0	0	1	1
endonuclease IV	1	0	0	1
thioredoxin reductase	4	0	0	4
nonstructural protein 1	2	0	0	2
glucocerebrosidase	1	0	0	1
peripheral myelin protein 22 isoform 1	1	0	0	1
DNA polymerase beta	1	0	0	1
DNA polymerase iota isoform a (long)	4	0	0	4
neuropeptide S receptor isoform A	1	0	0	1
Eyes absent homolog 2	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Amyloid-beta precursor protein	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Chain A, Beta-lactamase	2	0	0	2
Genome polyprotein	0	1	1	2
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
SMAD family member 2	3	0	0	3
GLS protein	2	0	0	2
SMAD family member 3	3	0	0	3
thioredoxin glutathione reductase	2	0	0	2
hypothetical protein, conserved	1	0	0	1
thyrotropin-releasing hormone receptor	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
eyes absent homolog 2 isoform a	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
Flavin reductase (NADPH)	0	0	1	1
large T antigen	0	1	0	1
importin subunit beta-1 isoform 1	1	0	0	1
snurportin-1	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Guanine nucleotide-binding protein G	1	0	0	1
interferon gamma precursor	0	0	0	1
streptokinase A precursor	0	0	1	1
Sodium/nucleoside cotransporter 2	0	3	0	3
Thymidylate synthase	0	1	0	2
Solute carrier family 15 member 1	0	1	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
GALC protein	2	0	0	2
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Carbonic anhydrase 12	0	0	0	2
Solute carrier family 22 member 3	0	1	0	2
Plasma kallikrein	0	0	0	2
Carbonic anhydrase 3	0	0	0	2
Macrophage migration inhibitory factor	0	2	0	2
Carbonic anhydrase 6	0	0	0	2
Adenosine receptor A1	0	0	0	2
5-hydroxytryptamine receptor 1D	0	0	0	1
Adenosine receptor A2a	0	0	0	2
Histamine H1 receptor	0	2	1	3
Metabotropic glutamate receptor 5	0	1	1	2
Carbonic anhydrase 5A, mitochondrial	0	0	0	2
Histamine H1 receptor	0	2	2	4
Glutamate receptor ionotropic, NMDA 1	0	2	0	4
Carbonic anhydrase 7	0	0	0	2
Carbonic anhydrase	0	0	0	3
Histamine H3 receptor	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	2	0	4
Glutamate receptor ionotropic, NMDA 2B	0	2	0	4
Glutamate receptor ionotropic, NMDA 2C	0	2	0	5
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase 9	0	1	1	4
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase-like protein, putative	0	0	0	2
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	0	0	3
Glutamate receptor ionotropic, NMDA 2D	0	2	0	4
Carbonic anhydrase	0	0	0	3
Equilibrative nucleoside transporter 4	0	0	0	1
Carbonic anhydrase 13	0	0	0	2
Glutamate receptor ionotropic, NMDA 3B	0	2	0	4
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carbonic anhydrase 4	0	0	0	1
Carbonic anhydrase 13	0	0	0	2
Histamine H3 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	2	0	4
Carbonic anhydrase 14	0	0	0	2
Carbonic anhydrase 5B, mitochondrial	0	0	0	2
Histamine H3 receptor	0	1	2	3
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	4	0	4
Intestinal-type alkaline phosphatase	0	3	0	3
Large neutral amino acids transporter small subunit 1	0	2	0	3
Proton-coupled amino acid transporter 1	0	1	0	2
Phospholipase A-2-activating protein	0	3	0	3
dopamine D1 receptor	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
flap endonuclease 1	1	0	0	1
Alkaline phosphatase, placental type	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	3
Intestinal-type alkaline phosphatase	0	2	0	2
Carboxylic ester hydrolase	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Secreted chorismate mutase	0	1	0	1
Transient receptor potential cation channel subfamily M member 8	0	1	2	4
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Transient receptor potential cation channel subfamily M member 8	0	0	1	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Muscarinic acetylcholine receptor M1	0	0	1	1
Muscarinic acetylcholine receptor M3	0	0	1	1
Muscarinic acetylcholine receptor M4	0	0	1	1
Muscarinic acetylcholine receptor M5	0	0	1	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Muscarinic acetylcholine receptor M1	0	0	1	2
Cytochrome P450 2B6	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Muscarinic acetylcholine receptor M4	0	0	1	2
Delta-type opioid receptor	0	0	0	1
Kappa-type opioid receptor	0	0	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Mu-type opioid receptor	0	0	0	1
Cholinesterase	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Sigma non-opioid intracellular receptor 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Monocarboxylate transporter 10	0	0	0	1
beta-2 adrenergic receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
Vpr	1	0	0	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Integrin beta-3	1	0	0	1
Integrin alpha-IIb	1	0	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Peroxisome proliferator-activated receptor alpha	1	0	0	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Cytochrome P450 14alpha-demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	0	1
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
polyadenylate-binding protein 1	0	1	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Thymidine kinase	0	1	0	2
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidine kinase	0	0	0	1
RAF proto-oncogene serine/threonine-protein kinase	0	1	0	1
Malate dehydrogenase	0	1	0	1
Serine/threonine-protein kinase B-raf	0	1	0	1
Chymotrypsinogen B	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
RAC-alpha serine/threonine-protein kinase	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 2	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
MAP kinase-activated protein kinase 5	0	1	0	1
Rap guanine nucleotide exchange factor 3	2	0	0	2
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Chain A, Cytidine Deaminase	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Cytidine deaminase	0	1	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Protein cereblon	0	2	0	2
Equilibrative nucleoside transporter 1	0	2	0	2
Uridine-cytidine kinase 1	0	0	0	1
Solute carrier family 28 member 3	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(2)

Research Excerpts

Overview

Research

Studies (147)

Protein Targets (519)

Blue Tongue

Synonyms(2)

Research Excerpts

Overview

Research

Studies (147)

Drugs Studied (91)

Protein Targets (519)