Any compound which acts on the peroxisome proliferator-activated receptor.
ChEBI ID: 70781
| Member | Definition | Class |
|---|---|---|
| diisobutyl phthalate | A phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of isobutanol. | diisobutyl phthalate |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 4 (3.64) | 18.7374 |
| 1990's | 1 (0.91) | 18.2507 |
| 2000's | 15 (13.64) | 29.6817 |
| 2010's | 60 (54.55) | 24.3611 |
| 2020's | 30 (27.27) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 1 (0.90%) | 5.53% |
| Reviews | 4 (3.60%) | 6.00% |
| Case Studies | 1 (0.90%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 105 (94.59%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 18.0722 | 3 | 5 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 61.6901 | 1 | 1 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| interleukin 8 | Homo sapiens (human) | Potency | 74.9780 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 33.4915 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 61.6901 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 15.3553 | 1 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 61.6901 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 18.8452 | 2 | 2 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 39.8107 | 2 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 52.9748 | 2 | 3 |