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cypermethrin and Acute Liver Injury, Drug-Induced

cypermethrin has been researched along with Acute Liver Injury, Drug-Induced in 12 studies

cypermethrin : A carboxylic ester resulting from the formal condensation between 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid and the alcoholic hydroxy group of hydroxy(3-phenoxyphenyl)acetonitrile.
zeta-cypermethrin : A diastereoisomeric mixture comprising the isomeric pair (1R)-cis-(alphaS)- and (1S)-trans-(alphaR)-cypermethrin together with the isomeric pair (1S)-cis-(alphaS)- and (1S)-trans-(alphaS)-cypermethrin where the ratio between the isomeric pairs lies in the range 45:55 to 55:45.

Research Excerpts

ExcerptRelevanceReference
"Cypermethrin (Cyp) is a pyrethroid that has been associated with the toxicity of various organs."5.91Hepatoprotective and Antioxidant Effects of Nanopiperine against Cypermethrin via Mitigation of Oxidative Stress, Inflammations and Gene Expression Using qRT-PCR. ( Al Shahi, H; Alam, MI; Ali, R; Alshahrani, S; Ashafaq, M; Hanbashi, A; Hussain, S; Jali, AM; Khairat, KHM; Khan, A; Mohammed, M; Qadri, M; Siddiqui, R, 2023)
" The toxic effects were evaluated considering the increases in serum hepatic biomarkers alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), total protein and albumin, and lipid peroxidation (LPO), as well as a decrease in antioxidative activity (reduced glutathione (GSH), superoxide dismutase (SOD), and catalase) and the upregulation of inflammatory cytokines (IL-1β, IL-6, and TNF-α)."1.91Hepatoprotective Effect of Curcumin Nano-Lipid Carrier against Cypermethrin Toxicity by Countering the Oxidative, Inflammatory, and Apoptotic Changes in Wistar Rats. ( Ahmed, RA; Alam, MI; Almoshari, Y; Alqahtani, SS; Alshahrani, S; Ashafaq, M; Bokar, IAM; Hussain, S; Jali, AM; Qadri, M; Siddiqui, R; Taha, MME, 2023)
"Cypermethrin (Cyp) is a pyrethroid that has been associated with the toxicity of various organs."1.91Hepatoprotective and Antioxidant Effects of Nanopiperine against Cypermethrin via Mitigation of Oxidative Stress, Inflammations and Gene Expression Using qRT-PCR. ( Al Shahi, H; Alam, MI; Ali, R; Alshahrani, S; Ashafaq, M; Hanbashi, A; Hussain, S; Jali, AM; Khairat, KHM; Khan, A; Mohammed, M; Qadri, M; Siddiqui, R, 2023)
" Low doses of carbendazim in combination with low doses of imazalil or cypermethrin caused very pronounced hepatic necrosis, more than any of the three individually applied pesticides or combination of imazalil and cypermethrin."1.38Carbendazim impends hepatic necrosis when combined with imazalil or cypermethrin. ( Benković, V; Dikić, D; Horvat-Knežević, A; Knežević, F; Landeka, I; Lončar, G; Mojsović-Ćuić, A; Rogić, D; Teparić, R, 2012)
"Cypermethrin (CM) is an important type II pyrethroid pesticide used extensively in pest control and is reported to cause hepatic and renal toxicity."1.36Aqueous extract of Trigonella foenum graecum (fenugreek) prevents cypermethrin-induced hepatotoxicity and nephrotoxicity. ( Devasena, T; Sushma, N, 2010)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's5 (41.67)24.3611
2020's5 (41.67)2.80

Authors

AuthorsStudies
Hussain, S3
Ashafaq, M2
Alshahrani, S2
Bokar, IAM1
Siddiqui, R2
Alam, MI2
Taha, MME1
Almoshari, Y1
Alqahtani, SS1
Ahmed, RA1
Jali, AM2
Qadri, M2
Khairat, KHM1
Ali, R1
Mohammed, M1
Khan, A2
Al Shahi, H1
Hanbashi, A1
He, K1
Tang, Q1
Gong, M1
Yang, S1
Chen, X1
Zhu, H1
Liu, D1
Huang, B1
Chen, L1
Wang, D2
Zhou, Z1
Diao, J1
Zhao, H1
Wang, Y1
Liu, Y1
Yin, K1
Li, B1
Yu, H1
Xing, M1
Zhang, J1
Liu, L1
Ren, L1
Feng, W1
Lv, P1
Wu, W1
Yan, Y1
Mossa, AT1
Heikal, TM1
Belaiba, M1
Raoelison, EG1
Ferhout, H1
Bouajila, J1
Khan, MZ1
Javed, I1
Asi, MR1
Sushma, N1
Devasena, T1
Dikić, D1
Landeka, I1
Knežević, F1
Mojsović-Ćuić, A1
Benković, V1
Horvat-Knežević, A1
Lončar, G1
Teparić, R1
Rogić, D1
Hidalgo-Castellón, AJ1
Ramos-Clemente, JI1
Pérez, MA1
Pilipchuk, LR1

Other Studies

12 other studies available for cypermethrin and Acute Liver Injury, Drug-Induced

ArticleYear
Hepatoprotective Effect of Curcumin Nano-Lipid Carrier against Cypermethrin Toxicity by Countering the Oxidative, Inflammatory, and Apoptotic Changes in Wistar Rats.
    Molecules (Basel, Switzerland), 2023, Jan-16, Volume: 28, Issue:2

    Topics: Animals; Antioxidants; bcl-2-Associated X Protein; Chemical and Drug Induced Liver Injury; Curcumin;

2023
Hepatoprotective and Antioxidant Effects of Nanopiperine against Cypermethrin via Mitigation of Oxidative Stress, Inflammations and Gene Expression Using qRT-PCR.
    International journal of molecular sciences, 2023, Oct-19, Volume: 24, Issue:20

    Topics: Animals; Antioxidants; Caspases; Chemical and Drug Induced Liver Injury; Cytokines; Gene Expression;

2023
A transcriptomic study of selenium against liver injury induced by beta-cypermethrin in mice by RNA-seq.
    Functional & integrative genomics, 2020, Volume: 20, Issue:3

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Insecticides; Janus

2020
Comparing alpha-cypermethrin induced dose/gender-dependent responses of lizards in hepatotoxicity and nephrotoxicity in a food chain.
    Chemosphere, 2020, Volume: 256

    Topics: Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Food Chai

2020
ROS-Induced Hepatotoxicity under Cypermethrin: Involvement of the Crosstalk between Nrf2/Keap1 and NF-κB/iκB-α Pathways Regulated by Proteasome.
    Environmental science & technology, 2021, 05-04, Volume: 55, Issue:9

    Topics: Animals; Carps; Chemical and Drug Induced Liver Injury; Diet; Fish Proteins; Kelch-Like ECH-Associat

2021
The single and joint toxicity effects of chlorpyrifos and beta-cypermethrin in zebrafish (Danio rerio) early life stages.
    Journal of hazardous materials, 2017, Jul-15, Volume: 334

    Topics: Adherens Junctions; Animals; Antioxidants; Apoptosis; Catalase; Cell Cycle; Chemical and Drug Induce

2017
Antioxidant activity and hepatoprotective potential of Cedrelopsis grevei on cypermethrin induced oxidative stress and liver damage in male mice.
    BMC complementary and alternative medicine, 2015, Jul-25, Volume: 15

    Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Liver; Male; Mice; Oxidative Stress;

2015
Toxico-pathological effects in rats induced by concurrent exposure to aflatoxin and cypermethrin.
    Toxicon : official journal of the International Society on Toxinology, 2009, Volume: 53, Issue:1

    Topics: Aflatoxins; Animals; Behavior, Animal; Body Weight; Chemical and Drug Induced Liver Injury; Dose-Res

2009
Aqueous extract of Trigonella foenum graecum (fenugreek) prevents cypermethrin-induced hepatotoxicity and nephrotoxicity.
    Human & experimental toxicology, 2010, Volume: 29, Issue:4

    Topics: Animals; Antioxidants; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease M

2010
Carbendazim impends hepatic necrosis when combined with imazalil or cypermethrin.
    Basic & clinical pharmacology & toxicology, 2012, Volume: 110, Issue:5

    Topics: Animals; Benzimidazoles; Biomarkers; Carbamates; Chemical and Drug Induced Liver Injury; Drug Intera

2012
[Toxic hepatitis after intake of raspberries].
    Medicina clinica, 2013, Jul-21, Volume: 141, Issue:2

    Topics: Chemical and Drug Induced Liver Injury; Food Contamination; Foodborne Diseases; Fruit; Fungicides, I

2013
[The clinical manifestations of acute cymbush poisoning].
    Vrachebnoe delo, 1991, Issue:4

    Topics: Acute Disease; Agricultural Workers' Diseases; Chemical and Drug Induced Liver Injury; Combined Moda

1991