racemetirosine has been researched along with Paraganglioma in 6 studies
alpha-Methyltyrosine: An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)
Paraganglioma: A neural crest tumor usually derived from the chromoreceptor tissue of a paraganglion, such as the carotid body, or medulla of the adrenal gland (usually called a chromaffinoma or pheochromocytoma). It is more common in women than in men. (Stedman, 25th ed; from Segen, Dictionary of Modern Medicine, 1992)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To describe outcomes of patients with metyrosine (MET) pretreatment for abdominal surgical resection of pheochromocytoma or paraganglioma (PCC/PGL) compared with patients who had phenoxybenzamine (PBZ) pretreatment." | 3.85 | Perioperative hemodynamics and outcomes of patients on metyrosine undergoing resection of pheochromocytoma or paraganglioma. ( Bancos, I; Butz, JJ; Cavalcante, AN; Martin, DP; McKenzie, TJ; Schroeder, DR; Sprung, J; Weingarten, TN; Young, WF, 2017) |
| " Sedation, anemia, and death were reported in 1 patient each as serious adverse drug reactions during the 24-week treatment." | 2.87 | Efficacy and safety of metyrosine in pheochromocytoma/paraganglioma: a multi-center trial in Japan. ( Harada, T; Ichihara, A; Imai, T; Katabami, T; Kawata, N; Matsuda, T; Naruse, M; Nomura, M; Okamoto, T; Satoh, F; Takekoshi, K; Tanabe, A; Tanaka, T; Tsuiki, M; Yamada, M, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Takekoshi, K | 2 |
| Satoh, F | 2 |
| Tanabe, A | 2 |
| Okamoto, T | 2 |
| Ichihara, A | 2 |
| Tsuiki, M | 2 |
| Katabami, T | 2 |
| Nomura, M | 2 |
| Tanaka, T | 2 |
| Matsuda, T | 2 |
| Imai, T | 2 |
| Yamada, M | 2 |
| Asada, S | 1 |
| Kawata, N | 2 |
| Naruse, M | 2 |
| Gruber, LM | 1 |
| Jasim, S | 1 |
| Ducharme-Smith, A | 1 |
| Weingarten, T | 1 |
| Young, WF | 2 |
| Bancos, I | 2 |
| Butz, JJ | 1 |
| Weingarten, TN | 1 |
| Cavalcante, AN | 1 |
| McKenzie, TJ | 1 |
| Schroeder, DR | 1 |
| Martin, DP | 1 |
| Sprung, J | 1 |
| Harada, T | 1 |
| Wachtel, H | 1 |
| Kennedy, EH | 1 |
| Zaheer, S | 1 |
| Bartlett, EK | 1 |
| Fishbein, L | 1 |
| Roses, RE | 1 |
| Fraker, DL | 1 |
| Cohen, DL | 1 |
| Triner, L | 1 |
| Baer, L | 1 |
| Gallagher, R | 1 |
| Weitzman, S | 1 |
1 review available for racemetirosine and Paraganglioma
| Article | Year |
|---|---|
The Role for Metyrosine in the Treatment of Patients With Pheochromocytoma and Paraganglioma.
Topics: Adrenal Gland Neoplasms; alpha-Methyltyrosine; Antineoplastic Combined Chemotherapy Protocols; Drug | 2021 |
2 trials available for racemetirosine and Paraganglioma
| Article | Year |
|---|---|
Correlation between urinary fractionated metanephrines in 24-hour and spot urine samples for evaluating the therapeutic effect of metyrosine: a subanalysis of a multicenter, open-label phase I/II study.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; alpha-Methyltyrosine; Child; Fe | 2019 |
Efficacy and safety of metyrosine in pheochromocytoma/paraganglioma: a multi-center trial in Japan.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; alpha-Methyltyrosine; Antineopl | 2018 |
3 other studies available for racemetirosine and Paraganglioma
| Article | Year |
|---|---|
Perioperative hemodynamics and outcomes of patients on metyrosine undergoing resection of pheochromocytoma or paraganglioma.
Topics: Adrenal Gland Neoplasms; Adult; alpha-Methyltyrosine; Blood Pressure; Drug Therapy, Combination; Enz | 2017 |
Preoperative Metyrosine Improves Cardiovascular Outcomes for Patients Undergoing Surgery for Pheochromocytoma and Paraganglioma.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; alpha-Methyltyrosine; Cardiovascular Diseases; Enzyme Inhibi | 2015 |
Use of metyrosine in the anaesthetic management of patients with catecholamine-secreting tumours. A case report.
Topics: alpha-Methyltyrosine; Anesthesia, Epidural; Catecholamines; Hernia, Inguinal; Humans; Intraoperative | 1982 |