metformin has been researched along with Paraganglioma in 2 studies
Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Paraganglioma: A neural crest tumor usually derived from the chromoreceptor tissue of a paraganglion, such as the carotid body, or medulla of the adrenal gland (usually called a chromaffinoma or pheochromocytoma). It is more common in women than in men. (Stedman, 25th ed; from Segen, Dictionary of Modern Medicine, 1992)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Using unique PGL cell models established in our laboratory, we evaluated the effect of dichloroacetate (DCA) as single agent or in a novel combination with other metabolic drugs, including GW6471 and metformin." | 5.48 | Effects of dichloroacetate as single agent or in combination with GW6471 and metformin in paraganglioma cells. ( Amoroso, R; Arduini, A; Cama, A; Cataldi, A; De Lellis, L; di Giacomo, V; Florio, R; Gallorini, M; Mariani-Costantini, R; Natale, A; Perconti, S; Sanna, M; Verginelli, F; Veschi, S, 2018) |
| " Using unique PGL cell models established in our laboratory, we evaluated the effect of dichloroacetate (DCA) as single agent or in a novel combination with other metabolic drugs, including GW6471 and metformin." | 1.48 | Effects of dichloroacetate as single agent or in combination with GW6471 and metformin in paraganglioma cells. ( Amoroso, R; Arduini, A; Cama, A; Cataldi, A; De Lellis, L; di Giacomo, V; Florio, R; Gallorini, M; Mariani-Costantini, R; Natale, A; Perconti, S; Sanna, M; Verginelli, F; Veschi, S, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Z | 1 |
| Tao, E | 1 |
| Chen, Y | 1 |
| Wang, Q | 1 |
| Liu, M | 1 |
| Wei, L | 1 |
| Xu, S | 1 |
| Chen, W | 1 |
| Zhong, C | 1 |
| Florio, R | 1 |
| De Lellis, L | 1 |
| Veschi, S | 1 |
| Verginelli, F | 1 |
| di Giacomo, V | 1 |
| Gallorini, M | 1 |
| Perconti, S | 1 |
| Sanna, M | 1 |
| Mariani-Costantini, R | 1 |
| Natale, A | 1 |
| Arduini, A | 1 |
| Amoroso, R | 1 |
| Cataldi, A | 1 |
| Cama, A | 1 |
2 other studies available for metformin and Paraganglioma
| Article | Year |
|---|---|
NDUFA4 promotes the progression of head and neck paraganglioma by inhibiting ferroptosis.
Topics: Adenosine Triphosphate; Animals; Electron Transport Complex IV; Ferroptosis; Humans; Metformin; Mice | 2023 |
Effects of dichloroacetate as single agent or in combination with GW6471 and metformin in paraganglioma cells.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Dichloroacetic Acid; Drug Screening Assays, | 2018 |