Page last updated: 2024-10-21

normetanephrine and Paraganglioma

normetanephrine has been researched along with Paraganglioma in 49 studies

Normetanephrine: A methylated metabolite of norepinephrine that is excreted in the urine and found in certain tissues. It is a marker for tumors.

Paraganglioma: A neural crest tumor usually derived from the chromoreceptor tissue of a paraganglion, such as the carotid body, or medulla of the adrenal gland (usually called a chromaffinoma or pheochromocytoma). It is more common in women than in men. (Stedman, 25th ed; from Segen, Dictionary of Modern Medicine, 1992)

Research Excerpts

ExcerptRelevanceReference
"This single-centre, prospective trial investigated the use of CST in 60 patients with suspected PPGL associated with out-patient elevations of plasma normetanephrine (NMN) and/or metanephrine (MN), in most cases accompanied with hypertension or an adrenal mass."9.51Clonidine suppression test for a reliable diagnosis of pheochromocytoma: When to use. ( Dralle, H; Führer, D; Geroula, A; Pamporaki, C; Schmid, KW; Tsiomidou, S; Unger, N; Van Baal, L; Weber, F, 2022)
"Various studies have validated plasma free metanephrines (MNs) as biomarkers for pheochromocytoma and paraganglioma (PPGL)."8.95ACCURACY OF PLASMA FREE METANEPHRINES IN THE DIAGNOSIS OF PHEOCHROMOCYTOMA AND PARAGANGLIOMA: A SYSTEMATIC REVIEW AND META-ANALYSIS. ( Cao, X; Chen, Y; Huang, X; Li, Y; Xiao, H; Zhou, X, 2017)
"Sampling of blood in the supine position for diagnosis of pheochromocytoma and paraganglioma (PPGL) results in lower rates of false positives for plasma normetanephrine than seated sampling."8.12Preanalytical Considerations and Outpatient Versus Inpatient Tests of Plasma Metanephrines to Diagnose Pheochromocytoma. ( Amar, L; Baron, S; Blanchard, A; Braun, L; Ceccato, F; Davies, E; Deinum, J; Deutschbein, T; Dobrowolski, P; Eisenhofer, G; Fassnacht, M; Gruber, S; Hampson, S; Januszewicz, A; Lenzini, L; Müller, LM; Nölting, S; Pamporaki, C; Pecori, A; Peitzsch, M; Pommer, G; Prejbisz, A; Remde, H; Rossi, GP; Stell, A; Timmers, HJLM; Zennaro, MC, 2022)
"Accurate diagnosis of pheochromocytoma and paraganglioma (PPGLs) is highly dependent on the detection of metanephrines and catecholamines."8.02Study of stability and interference for catecholamines and metanephrines, 3-methoxytyramine: key point of an accurate diagnosis for pheochromocytoma and paraganglioma. ( Cong, H; Gao, X; Guo, Y; Shi, X; Sun, N; Wang, K; Xie, L; Zhang, W; Zhou, Z, 2021)
"Measurements of plasma free metanephrines are recommended for diagnosing pheochromocytomas and paragangliomas (PPGL)."8.02Diagnostic Accuracy of Salivary Metanephrines in Pheochromocytomas and Paragangliomas. ( Eijkelenkamp, K; Kema, IP; Kerstens, MN; Links, TP; Osinga, TE; Pacak, K; Sluiter, WJ; van der Horst-Schrivers, ANA; van Faassen, M, 2021)
"The 24 h urinary-fractionated metanephrine (MN) and normetanephrine (NMN) are recommended as the preferred indicators for laboratory diagnosis of pheochromocytoma and paraganglioma (PPGL)."7.96Stability and reference intervals of spot urinary fractionated metanephrines and methoxytyramine by tandem mass spectrometry as a screening method for pheochromocytoma and paraganglioma. ( Cong, H; Dai, S; Gao, X; Shi, X; Wang, K; Zhang, W; Zhou, Z, 2020)
"Urinary measurement of fractionated metanephrines is one of the best available biochemical tests for the diagnosis of pheochromocytoma and paraganglioma; however, false-positive results remain an issue."7.96Clinical factors affecting spot urine fractionated metanephrines in patients suspected pheochromocytoma/paraganglioma. ( Bokuda, K; Ichihara, A; Seki, Y; Yatabe, M, 2020)
"Plasma free metanephrines are commonly used for diagnosis of pheochromocytoma and paraganglioma (PPGLs), but can also provide other information."7.96Plasma metanephrines and prospective prediction of tumor location, size and mutation type in patients with pheochromocytoma and paraganglioma. ( Bechmann, N; Beuschlein, F; Calsina, B; Constantinescu, G; Deutschbein, T; Eisenhofer, G; Fankhauser, M; Fassnacht, M; Fliedner, S; Langton, K; Lenders, JWM; Monteagudo, M; Nölting, S; Pamporaki, C; Peitzsch, M; Prejbisz, A; Robledo, M; Stell, A; Timmers, HJLM, 2020)
"In patients with phaeochromocytomas or paragangliomas (PPGLs), 24-h urine collections for metanephrines (uMNs) are cumbersome."7.96Random 'spot' urinary metanephrines compared with 24-h-urinary and plasma results in phaeochromocytomas and paragangliomas. ( Grossman, AB; Isidori, AM; Jafar-Mohammadi, B; James, T; Maunsell, Z; May, CJH; Sbardella, E; Shine, B; Tadman, M, 2020)
"This work discusses the clinical performance of deconjugated metanephrine (MN), normetanephrine (NMN) and 3-methoxytyramine (3MT) determined in the basal first morning urine using a chromatographic method with electrochemical detection for the clinical diagnosis of pheochromocytoma (PHEO) and paraganglioma (PGL)."7.81Deconjugated urinary metanephrine, normetanephrine and 3-methoxytyramine in laboratory diagnosis of pheochromocytoma and paraganglioma. ( Bešťák, J; Bílek, R; Dušková, J; Michalský, D; Novák, K; Vlček, P; Widimský, J; Zelinka, T, 2015)
"Measurement of plasma free metanephrines by immunoassay appears to be a useful diagnostic test in patients suspected of pheochromocytoma, with a high specificity as compared with urinary catecholamines."7.77Comparison of plasma metanephrines measured by a commercial immunoassay and urinary catecholamines in the diagnosis of pheochromocytoma. ( Christensen, TT; Frystyk, J; Poulsen, PL, 2011)
"This single-centre, prospective trial investigated the use of CST in 60 patients with suspected PPGL associated with out-patient elevations of plasma normetanephrine (NMN) and/or metanephrine (MN), in most cases accompanied with hypertension or an adrenal mass."5.51Clonidine suppression test for a reliable diagnosis of pheochromocytoma: When to use. ( Dralle, H; Führer, D; Geroula, A; Pamporaki, C; Schmid, KW; Tsiomidou, S; Unger, N; Van Baal, L; Weber, F, 2022)
"Plasma-free metanephrines measured by EIA have better diagnostic test characteristics than urinary catecholamines in the diagnosis of pheochromocytoma."5.14Evaluation of an enzyme immunoassay for plasma-free metanephrines in the diagnosis of catecholamine-secreting tumors. ( Akker, SA; Burrin, J; Chew, SL; Drake, WM; Finney, H; Grossman, AB; Procopiou, M, 2009)
"Various studies have validated plasma free metanephrines (MNs) as biomarkers for pheochromocytoma and paraganglioma (PPGL)."4.95ACCURACY OF PLASMA FREE METANEPHRINES IN THE DIAGNOSIS OF PHEOCHROMOCYTOMA AND PARAGANGLIOMA: A SYSTEMATIC REVIEW AND META-ANALYSIS. ( Cao, X; Chen, Y; Huang, X; Li, Y; Xiao, H; Zhou, X, 2017)
"Measurements of plasma metanephrines and methoxytyramine provide a sensitive test for diagnosis of pheochromocytoma/paraganglioma."4.84False-positive results for pheochromocytoma associated with norepinephrine reuptake blockade. ( Biemann, R; Eisenhofer, G; Pamporaki, C; Peitzsch, M; Rayes, N; Rohm, S; Sabri, O; Sandner, B; Schürfeld, R; Tönjes, A, 2024)
"Moderately elevated plasma normetanephrine (NMN) levels are frequent among patients with suspected pheochromocytoma and paraganglioma (PPGL)."4.12Improved Diagnostic Accuracy of Clonidine Suppression Testing Using an Age-Related Cutoff for Plasma Normetanephrine. ( Deutschbein, T; Eisenhofer, G; Fassnacht, M; Fuss, CT; Masjkur, J; Nölting, S; Pamporaki, C; Prejbisz, A; Quinkler, M; Remde, H; Timmers, HJLM, 2022)
"Sampling of blood in the supine position for diagnosis of pheochromocytoma and paraganglioma (PPGL) results in lower rates of false positives for plasma normetanephrine than seated sampling."4.12Preanalytical Considerations and Outpatient Versus Inpatient Tests of Plasma Metanephrines to Diagnose Pheochromocytoma. ( Amar, L; Baron, S; Blanchard, A; Braun, L; Ceccato, F; Davies, E; Deinum, J; Deutschbein, T; Dobrowolski, P; Eisenhofer, G; Fassnacht, M; Gruber, S; Hampson, S; Januszewicz, A; Lenzini, L; Müller, LM; Nölting, S; Pamporaki, C; Pecori, A; Peitzsch, M; Pommer, G; Prejbisz, A; Remde, H; Rossi, GP; Stell, A; Timmers, HJLM; Zennaro, MC, 2022)
"Increased plasma normetanephrine levels in patients with CCHD can be explained by the effect of hypoxia."4.12Comparison of plasma metanephrines in patients with cyanotic and acyanotic congenital heart disease. ( Goricar, K; Janež, A; Jensterle, M; Podbregar, A; Prokšelj, K; Rakusa, M, 2022)
"Accurate diagnosis of pheochromocytoma and paraganglioma (PPGLs) is highly dependent on the detection of metanephrines and catecholamines."4.02Study of stability and interference for catecholamines and metanephrines, 3-methoxytyramine: key point of an accurate diagnosis for pheochromocytoma and paraganglioma. ( Cong, H; Gao, X; Guo, Y; Shi, X; Sun, N; Wang, K; Xie, L; Zhang, W; Zhou, Z, 2021)
"Biochemical testing of urinary metanephrines is useful in the diagnosis and monitoring of pheochromocytoma and paragangliomas."4.02Verifying Clinically Derived Reference Intervals for Daily Excretion Rates of Fractionated Metanephrines Using Modern Indirect Reference Interval Models. ( Doyle, K; Frank, EL, 2021)
"Measurements of plasma free metanephrines are recommended for diagnosing pheochromocytomas and paragangliomas (PPGL)."4.02Diagnostic Accuracy of Salivary Metanephrines in Pheochromocytomas and Paragangliomas. ( Eijkelenkamp, K; Kema, IP; Kerstens, MN; Links, TP; Osinga, TE; Pacak, K; Sluiter, WJ; van der Horst-Schrivers, ANA; van Faassen, M, 2021)
"In patients with phaeochromocytomas or paragangliomas (PPGLs), 24-h urine collections for metanephrines (uMNs) are cumbersome."3.96Random 'spot' urinary metanephrines compared with 24-h-urinary and plasma results in phaeochromocytomas and paragangliomas. ( Grossman, AB; Isidori, AM; Jafar-Mohammadi, B; James, T; Maunsell, Z; May, CJH; Sbardella, E; Shine, B; Tadman, M, 2020)
" She had elevated 24-hour urinary normetanephrine and was found to have a paraganglioma arising from the urinary bladder infiltrating the sigmoid colon."3.96Micturition syncope: a rare presentation of bladder paraganglioma. ( Iyyadurai, R; John, K; Nawahirsha, S; Sunil V, N, 2020)
"Plasma free metanephrines are commonly used for diagnosis of pheochromocytoma and paraganglioma (PPGLs), but can also provide other information."3.96Plasma metanephrines and prospective prediction of tumor location, size and mutation type in patients with pheochromocytoma and paraganglioma. ( Bechmann, N; Beuschlein, F; Calsina, B; Constantinescu, G; Deutschbein, T; Eisenhofer, G; Fankhauser, M; Fassnacht, M; Fliedner, S; Langton, K; Lenders, JWM; Monteagudo, M; Nölting, S; Pamporaki, C; Peitzsch, M; Prejbisz, A; Robledo, M; Stell, A; Timmers, HJLM, 2020)
"Urinary measurement of fractionated metanephrines is one of the best available biochemical tests for the diagnosis of pheochromocytoma and paraganglioma; however, false-positive results remain an issue."3.96Clinical factors affecting spot urine fractionated metanephrines in patients suspected pheochromocytoma/paraganglioma. ( Bokuda, K; Ichihara, A; Seki, Y; Yatabe, M, 2020)
"The 24 h urinary-fractionated metanephrine (MN) and normetanephrine (NMN) are recommended as the preferred indicators for laboratory diagnosis of pheochromocytoma and paraganglioma (PPGL)."3.96Stability and reference intervals of spot urinary fractionated metanephrines and methoxytyramine by tandem mass spectrometry as a screening method for pheochromocytoma and paraganglioma. ( Cong, H; Dai, S; Gao, X; Shi, X; Wang, K; Zhang, W; Zhou, Z, 2020)
"This work discusses the clinical performance of deconjugated metanephrine (MN), normetanephrine (NMN) and 3-methoxytyramine (3MT) determined in the basal first morning urine using a chromatographic method with electrochemical detection for the clinical diagnosis of pheochromocytoma (PHEO) and paraganglioma (PGL)."3.81Deconjugated urinary metanephrine, normetanephrine and 3-methoxytyramine in laboratory diagnosis of pheochromocytoma and paraganglioma. ( Bešťák, J; Bílek, R; Dušková, J; Michalský, D; Novák, K; Vlček, P; Widimský, J; Zelinka, T, 2015)
"Measurement of plasma/urinary catecholamine metabolites--especially normetanephrine (NMN)--represents a gold standard in biochemical detection of succinate dehydrogenase subunit B (SDHB) and D (SDHD)-related pheochromocytomas (PHEO) and paragangliomas (PGL)."3.80Clinical utility of chromogranin A in SDHx-related paragangliomas. ( Eisenhofer, G; Kantorovich, V; Pacak, K; Prodanov, T; Wesley, R; Zuber, S, 2014)
"Measurements of plasma normetanephrine (NMN) and metanephrine (MN) provide a sensitive test for diagnosis of phaeochromocytomas and paragangliomas (PPGLs), but do not allow detection of dopamine-producing tumours."3.79Analysis of plasma 3-methoxytyramine, normetanephrine and metanephrine by ultraperformance liquid chromatography-tandem mass spectrometry: utility for diagnosis of dopamine-producing metastatic phaeochromocytoma. ( Arlt, W; Beuschlein, F; Eisenhofer, G; Januszewicz, A; Kroiß, M; Peitzsch, M; Prejbisz, A; Siegert, G, 2013)
"Measurement of plasma free metanephrines by immunoassay appears to be a useful diagnostic test in patients suspected of pheochromocytoma, with a high specificity as compared with urinary catecholamines."3.77Comparison of plasma metanephrines measured by a commercial immunoassay and urinary catecholamines in the diagnosis of pheochromocytoma. ( Christensen, TT; Frystyk, J; Poulsen, PL, 2011)
"Vaginal paraganglioma are rare, atypical, solitary tumors which originate from the female genital tract."1.62Solitary vaginal paraganglioma with mature sacrococcygeal teratoma: a rare case report. ( Fan, H; Fan, J; Seery, S; Wang, W; Wang, Z; Zhang, Y, 2021)
"Hence, paragangliomas are occasionally misdiagnosed, and this results in unanticipated intraoperative hypertensive crisis."1.56Micturition syncope secondary to urinary bladder paraganglioma. ( Cherian, KE; Johnson, JT; Kapoor, N; Paul, TV, 2020)
"The paraganglioma is a rare tumour that can sometimes develop near to the pancreatic gland and can occasionally mimic an intra pancreatic mass."1.34[Difficult diagnosis of a pancreatic paraganglioma]. ( Crozes, C; Faucompret, S; Milou, F; Pavic, M; Perrot, G; Vincent, E, 2007)
"Paragangliomas are rare neuroendocrine tumors and the malignant behaviour, higher than pheochromocytomas, is based on metastases or local recurrence."1.30[Secreting retroperitoneal paraganglioma. Apropos of a case]. ( Farthouat, P; Meusnier, F; Platel, JP; Pourrière, M; Thouard, H, 1997)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.04)18.7374
1990's1 (2.04)18.2507
2000's4 (8.16)29.6817
2010's21 (42.86)24.3611
2020's22 (44.90)2.80

Authors

AuthorsStudies
Wang, K2
Gao, X2
Zhang, W2
Sun, N1
Xie, L1
Cong, H2
Guo, Y1
Shi, X2
Zhou, Z2
Kamihara, J1
Hamilton, KV1
Pollard, JA1
Clinton, CM1
Madden, JA1
Lin, J1
Imamovic, A1
Wall, CB1
Wassner, AJ1
Weil, BR1
Heeney, MM1
Vargas, SO1
Kaelin, WG1
Janeway, KA1
Perini, RF1
Zojwalla, NJ1
Voss, SD1
DuBois, SG1
Richter, S2
Qiu, B1
Ghering, M1
Kunath, C1
Constantinescu, G2
Luths, C1
Pamporaki, C7
Bechmann, N2
Meuter, L1
Kwapiszewska, A1
Deutschbein, T5
Nölting, S4
Peitzsch, M8
Robledo, M3
Prejbisz, A7
Pacak, K7
Gudziol, V1
Timmers, HJLM4
Eisenhofer, G13
Tsiomidou, S1
Geroula, A1
Van Baal, L1
Weber, F1
Dralle, H1
Schmid, KW1
Führer, D1
Unger, N1
Remde, H2
Quinkler, M1
Masjkur, J1
Fuss, CT1
Fassnacht, M4
Pommer, G1
Müller, LM1
Braun, L1
Gruber, S1
Pecori, A1
Hampson, S1
Davies, E1
Stell, A3
Rossi, GP1
Lenzini, L1
Ceccato, F1
Deinum, J1
Amar, L1
Blanchard, A1
Baron, S1
Dobrowolski, P1
Januszewicz, A4
Zennaro, MC1
Jensterle, M1
Podbregar, A1
Janež, A1
Rakusa, M1
Goricar, K1
Prokšelj, K1
Zeng, HL1
Wang, X1
Li, HJ1
Yang, Q1
Tan, JL1
Toh, PY1
Ling, S1
De Filpo, G1
Parenti, G1
Sparano, C1
Rastrelli, G1
Rapizzi, E1
Martinelli, S1
Amore, F1
Badii, B1
Paolo, P1
Ercolino, T1
Mannelli, M3
Maggi, M1
Canu, L1
Schürfeld, R1
Rayes, N1
Sabri, O1
Rohm, S1
Biemann, R1
Sandner, B1
Tönjes, A1
Takekoshi, K1
Satoh, F1
Tanabe, A1
Okamoto, T1
Ichihara, A2
Tsuiki, M1
Katabami, T1
Nomura, M1
Tanaka, T1
Matsuda, T1
Imai, T1
Yamada, M1
Asada, S1
Kawata, N1
Naruse, M1
Bokuda, K1
Yatabe, M1
Seki, Y1
Johnson, JT1
Cherian, KE1
Kapoor, N1
Paul, TV1
Dai, S1
Sbardella, E1
Maunsell, Z1
May, CJH1
Tadman, M1
James, T1
Jafar-Mohammadi, B1
Isidori, AM1
Grossman, AB3
Shine, B1
Fowler, D1
Irving, H1
Borzi, P1
Trnka, P1
Huynh, T1
Sunil V, N1
John, K1
Nawahirsha, S1
Iyyadurai, R1
Langton, K1
Calsina, B1
Monteagudo, M1
Fliedner, S2
Fankhauser, M1
Beuschlein, F3
Lenders, JWM1
Jian, M1
Huang, H1
Li, K1
Chuan, L1
Li, L1
Jiang, L1
Doyle, K1
Frank, EL1
Eijkelenkamp, K1
Osinga, TE2
van Faassen, M1
Kema, IP2
Kerstens, MN1
Sluiter, WJ1
Links, TP1
van der Horst-Schrivers, ANA1
Wang, Z1
Fan, H1
Fan, J1
Seery, S1
Wang, W1
Zhang, Y1
Chen, Y1
Xiao, H2
Zhou, X1
Huang, X1
Li, Y1
Cao, X1
Hulkower, R1
Gubbi, S1
Meholli, M1
Schubart, U1
Gieldon, L1
Masjkur, JR1
Därr, R1
Lahera, M1
Aust, D1
Zeugner, S1
Rump, A1
Hackmann, K1
Tzschach, A1
Schrock, E1
Klink, B1
Yan, Q1
Bancos, I1
Gruber, LM1
Bancos, C1
McKenzie, TJ1
Babovic-Vuksanovic, D1
Young, WF1
Wcislak, SM1
King, WS1
Waller, BR1
Goins, N1
Dickson, PV1
Mangelis, A1
Huebner, A1
Boyd, J1
Leung, AA1
Sadrzadeh, HS1
Kline, GA1
Kroiß, M1
Arlt, W1
Siegert, G3
Brown, S1
Pelzel, D1
Lattke, P1
Glöckner, S1
Reichmann, H1
van Berkel, A1
Lenders, JW2
Timmers, HJ2
Zuber, S1
Wesley, R1
Prodanov, T1
Kantorovich, V1
Oleaga-Alday, A1
Goñi-Goicoechea, F1
Calles-Romero, L1
Pérez de Ciriza-Cordeu, M1
Paja-Fano, M1
Teixeira, J1
Almeida, M1
Afonso, M1
Pinto, A1
Bílek, R1
Zelinka, T1
Vlček, P1
Dušková, J1
Michalský, D1
Novák, K1
Bešťák, J1
Widimský, J1
Procopiou, M1
Finney, H1
Akker, SA1
Chew, SL1
Drake, WM1
Burrin, J1
Vesin, C1
Cadi, P1
Thony, F1
Picard, JC1
Descotes, JL1
Calizzano, A1
Baguet, JP1
Swaminathan, K1
Duvall, E1
Akyol, M1
Van Der Horst-Schrivers, AN1
Van Der Laan, BF1
Dullaart, RP1
Christensen, TT1
Frystyk, J1
Poulsen, PL1
Bornstein, SR2
Friberg, P1
Milosevic, D1
Linehan, WM1
Adams, K1
KANDRAC, M1
JIRGL, V1
Ahlman, H1
Gimenez-Roqueplo, AP1
Kimura, N1
McNicol, AM1
Tischler, AS1
Perrot, G1
Pavic, M1
Milou, F1
Crozes, C1
Faucompret, S1
Vincent, E1
Farthouat, P1
Platel, JP1
Meusnier, F1
Pourrière, M1
Thouard, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pheochromocytoma Randomised Study Comparing Adrenoreceptor Inhibiting Agents for Preoperative Treatment[NCT01379898]Phase 4134 participants (Actual)Interventional2011-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for normetanephrine and Paraganglioma

ArticleYear
ACCURACY OF PLASMA FREE METANEPHRINES IN THE DIAGNOSIS OF PHEOCHROMOCYTOMA AND PARAGANGLIOMA: A SYSTEMATIC REVIEW AND META-ANALYSIS.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2017, Volume: 23, Issue:10

    Topics: Adrenal Gland Neoplasms; Biomarkers; Chromatography, Liquid; Humans; Immunoenzyme Techniques; Metane

2017
Diagnosis of endocrine disease: Biochemical diagnosis of phaeochromocytoma and paraganglioma.
    European journal of endocrinology, 2014, Volume: 170, Issue:3

    Topics: Adrenal Gland Neoplasms; Adult; Biomarkers, Tumor; Catecholamines; Dopamine; False Negative Reaction

2014
Laboratory evaluation of pheochromocytoma and paraganglioma.
    Clinical chemistry, 2014, Volume: 60, Issue:12

    Topics: Adrenal Gland Neoplasms; Clinical Laboratory Techniques; Dopamine; Humans; Metanephrine; Normetaneph

2014

Trials

3 trials available for normetanephrine and Paraganglioma

ArticleYear
Clonidine suppression test for a reliable diagnosis of pheochromocytoma: When to use.
    Clinical endocrinology, 2022, Volume: 97, Issue:5

    Topics: Adrenal Gland Neoplasms; Clonidine; Humans; Hypertension; Metanephrine; Normetanephrine; Paraganglio

2022
Correlation between urinary fractionated metanephrines in 24-hour and spot urine samples for evaluating the therapeutic effect of metyrosine: a subanalysis of a multicenter, open-label phase I/II study.
    Endocrine journal, 2019, Dec-25, Volume: 66, Issue:12

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; alpha-Methyltyrosine; Child; Fe

2019
Evaluation of an enzyme immunoassay for plasma-free metanephrines in the diagnosis of catecholamine-secreting tumors.
    European journal of endocrinology, 2009, Volume: 161, Issue:1

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Catecholamines; Child; Cohort S

2009

Other Studies

43 other studies available for normetanephrine and Paraganglioma

ArticleYear
Study of stability and interference for catecholamines and metanephrines, 3-methoxytyramine: key point of an accurate diagnosis for pheochromocytoma and paraganglioma.
    Scandinavian journal of clinical and laboratory investigation, 2021, Volume: 81, Issue:7

    Topics: Adrenal Gland Neoplasms; Anticoagulants; Catecholamines; Dopamine; Epinephrine; Hemoglobins; Humans;

2021
Belzutifan, a Potent HIF2α Inhibitor, in the Pacak-Zhuang Syndrome.
    The New England journal of medicine, 2021, 11-25, Volume: 385, Issue:22

    Topics: Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Basic Helix-Loop-Helix Transcription Factors; B

2021
Head/neck paragangliomas: focus on tumor location, mutational status and plasma methoxytyramine.
    Endocrine-related cancer, 2022, 03-21, Volume: 29, Issue:4

    Topics: Catecholamines; Dopamine; Female; Head and Neck Neoplasms; Humans; Male; Mutation; Normetanephrine;

2022
Improved Diagnostic Accuracy of Clonidine Suppression Testing Using an Age-Related Cutoff for Plasma Normetanephrine.
    Hypertension (Dallas, Tex. : 1979), 2022, Volume: 79, Issue:6

    Topics: Adrenal Gland Neoplasms; Clonidine; Humans; Metanephrine; Normetanephrine; Paraganglioma; Pheochromo

2022
Preanalytical Considerations and Outpatient Versus Inpatient Tests of Plasma Metanephrines to Diagnose Pheochromocytoma.
    The Journal of clinical endocrinology and metabolism, 2022, 08-18, Volume: 107, Issue:9

    Topics: Adrenal Gland Neoplasms; Humans; Inpatients; Metanephrine; Normetanephrine; Outpatients; Paraganglio

2022
Comparison of plasma metanephrines in patients with cyanotic and acyanotic congenital heart disease.
    Endocrine, 2022, Volume: 78, Issue:3

    Topics: Adrenal Gland Neoplasms; Adult; Cross-Sectional Studies; Female; Heart Defects, Congenital; Humans;

2022
Quantitative analysis of catecholamines and their metabolites in 491 patients with adrenal tumors: a retrospective single-center cohort study.
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:8

    Topics: Adrenal Gland Neoplasms; Cohort Studies; Humans; Metanephrine; Normetanephrine; Paraganglioma; Pheoc

2023
Unusual presentation of a rare catecholamine-secreting sinonasal paraganglioma.
    BMJ case reports, 2023, May-02, Volume: 16, Issue:5

    Topics: Catecholamines; Humans; Male; Normetanephrine; Paraganglioma; Tomography, X-Ray Computed

2023
Hemodynamic parameters in patients undergoing surgery for pheochromocytoma/paraganglioma: a retrospective study.
    World journal of surgical oncology, 2023, Jun-27, Volume: 21, Issue:1

    Topics: Adrenal Gland Neoplasms; Catecholamines; Doxazosin; Female; Hemodynamics; Humans; Male; Middle Aged;

2023
False-positive results for pheochromocytoma associated with norepinephrine reuptake blockade.
    Endocrine-related cancer, 2024, Jan-01, Volume: 31, Issue:1

    Topics: Adrenal Gland Neoplasms; Antidepressive Agents, Tricyclic; Humans; Metanephrine; Norepinephrine; Nor

2024
Clinical factors affecting spot urine fractionated metanephrines in patients suspected pheochromocytoma/paraganglioma.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2020, Volume: 43, Issue:6

    Topics: Adrenal Gland Neoplasms; Adult; Age Factors; Aged; Aged, 80 and over; Female; Humans; Male; Metaneph

2020
Micturition syncope secondary to urinary bladder paraganglioma.
    BMJ case reports, 2020, Mar-12, Volume: 13, Issue:3

    Topics: 3-Iodobenzylguanidine; Adrenergic alpha-1 Receptor Antagonists; Adult; Diagnosis, Differential; Diag

2020
Stability and reference intervals of spot urinary fractionated metanephrines and methoxytyramine by tandem mass spectrometry as a screening method for pheochromocytoma and paraganglioma.
    Endocrine, 2020, Volume: 69, Issue:1

    Topics: Adrenal Gland Neoplasms; Chromatography, Liquid; Dopamine; Female; Humans; Male; Metanephrine; Norme

2020
Random 'spot' urinary metanephrines compared with 24-h-urinary and plasma results in phaeochromocytomas and paragangliomas.
    European journal of endocrinology, 2020, Volume: 183, Issue:2

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Age Factors; Aged; Aged, 80 and over; Area Under Curve;

2020
A Rare and Unusual Cause of Unilateral Ureteric Obstruction in a Child.
    Clinical chemistry, 2020, 08-01, Volume: 66, Issue:8

    Topics: Child; Female; Humans; Norepinephrine; Normetanephrine; Paraganglioma; Ureteral Neoplasms; Ureteral

2020
Micturition syncope: a rare presentation of bladder paraganglioma.
    BMJ case reports, 2020, Sep-02, Volume: 13, Issue:9

    Topics: Aged; Cystectomy; Female; Humans; Normetanephrine; Paraganglioma; Syncope; Treatment Outcome; Ultras

2020
Plasma metanephrines and prospective prediction of tumor location, size and mutation type in patients with pheochromocytoma and paraganglioma.
    Clinical chemistry and laboratory medicine, 2020, 10-01, Volume: 59, Issue:2

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Algorithms; Biomarkers, Tumor; Dopamine; Fe

2020
A 3-min UPLC-MS/MS method for the simultaneous determination of plasma catecholamines and their metabolites: Method verification and diagnostic efficiency.
    Clinical biochemistry, 2021, Volume: 87

    Topics: Adrenal Gland Neoplasms; Calibration; Catecholamines; Chromatography, Liquid; Dopamine; Female; Huma

2021
Verifying Clinically Derived Reference Intervals for Daily Excretion Rates of Fractionated Metanephrines Using Modern Indirect Reference Interval Models.
    American journal of clinical pathology, 2021, Sep-08, Volume: 156, Issue:4

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Child; Female; Humans; Likeliho

2021
Diagnostic Accuracy of Salivary Metanephrines in Pheochromocytomas and Paragangliomas.
    Clinical chemistry, 2021, 08-05, Volume: 67, Issue:8

    Topics: Adrenal Gland Neoplasms; Adult; Chromatography, Liquid; Humans; Male; Metanephrine; Normetanephrine;

2021
Solitary vaginal paraganglioma with mature sacrococcygeal teratoma: a rare case report.
    BMC endocrine disorders, 2021, Jul-07, Volume: 21, Issue:1

    Topics: Adult; Female; Humans; Magnetic Resonance Imaging; Norepinephrine; Normetanephrine; Paraganglioma; S

2021
Hypertensive emergency masquerading as phaeochromocytoma: a report of two cases.
    BMJ case reports, 2017, Aug-07, Volume: 2017

    Topics: Adrenal Gland Neoplasms; Aged; Diagnosis, Differential; False Positive Reactions; Humans; Hypertensi

2017
Next-generation panel sequencing identifies
    European journal of endocrinology, 2018, Volume: 178, Issue:2

    Topics: Adrenal Gland Neoplasms; Adult; Base Sequence; Carcinoma, Neuroendocrine; Codon, Nonsense; Epinephri

2018
When Biochemical Phenotype Predicts Genotype: Pheochromocytoma and Paraganglioma.
    The American journal of medicine, 2018, Volume: 131, Issue:5

    Topics: Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Female; Genotype; Germ-Line Mutatio

2018
Multifocal pheochromocytoma-paraganglioma in a 29-year-old woman with cyanotic congenital heart disease.
    Surgery, 2019, Volume: 165, Issue:1

    Topics: Adrenal Gland Neoplasms; Adult; Female; Heart Defects, Congenital; Humans; Norepinephrine; Normetane

2019
Age-specific pediatric reference intervals for plasma free normetanephrine, metanephrine, 3-methoxytyramine and 3-O-methyldopa: Particular importance for early infancy.
    Clinica chimica acta; international journal of clinical chemistry, 2019, Volume: 494

    Topics: Adolescent; Adrenal Gland Neoplasms; Aging; Blood Chemical Analysis; Catecholamines; Child; Child, P

2019
A high rate of modestly elevated plasma normetanephrine in a population referred for suspected PPGL when measured in a seated position.
    European journal of endocrinology, 2019, Volume: 181, Issue:3

    Topics: Adrenal Gland Neoplasms; Adult; Canada; Female; Humans; Male; Middle Aged; Normetanephrine; Paragang

2019
Analysis of plasma 3-methoxytyramine, normetanephrine and metanephrine by ultraperformance liquid chromatography-tandem mass spectrometry: utility for diagnosis of dopamine-producing metastatic phaeochromocytoma.
    Annals of clinical biochemistry, 2013, Volume: 50, Issue:Pt 2

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Blood Chemical Analysis; Chromatography, High Pressure Liquid;

2013
Levodopa therapy in Parkinson's disease: influence on liquid chromatographic tandem mass spectrometric-based measurements of plasma and urinary normetanephrine, metanephrine and methoxytyramine.
    Annals of clinical biochemistry, 2014, Volume: 51, Issue:Pt 1

    Topics: Aged; Aged, 80 and over; Chromatography, Liquid; Dopamine; Epinephrine; Female; Humans; Levodopa; Ma

2014
Clinical utility of chromogranin A in SDHx-related paragangliomas.
    European journal of clinical investigation, 2014, Volume: 44, Issue:4

    Topics: Adult; Aged; Biomarkers; Child; Child, Preschool; Chromogranin A; Head and Neck Neoplasms; Humans; M

2014
Paraganglioma and cyanotic congenital heart disease: The role of tisular hipoxia.
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2015, Volume: 62, Issue:8

    Topics: Adult; Biomarkers, Tumor; Cyanosis; Disease Susceptibility; Eisenmenger Complex; Female; Gene Expres

2015
Much more than anxiety...
    BMJ case reports, 2015, Aug-05, Volume: 2015

    Topics: 3-Iodobenzylguanidine; Abdomen; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Anxiety; Chromo

2015
Deconjugated urinary metanephrine, normetanephrine and 3-methoxytyramine in laboratory diagnosis of pheochromocytoma and paraganglioma.
    Physiological research, 2015, Volume: 64, Issue:Suppl 2

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Biomarkers; Chromatography, High Pressure Liquid; Clinical Lab

2015
A rare cause of complicated hypertension: urinary bladder paraganglioma.
    Southern medical journal, 2009, Volume: 102, Issue:11

    Topics: Adult; Humans; Hypertension; Magnetic Resonance Imaging; Male; Normetanephrine; Paraganglioma; Posit

2009
When numbers do not add up!
    QJM : monthly journal of the Association of Physicians, 2011, Volume: 104, Issue:11

    Topics: Diagnosis, Differential; Humans; Kidney Neoplasms; Male; Metanephrine; Middle Aged; Normetanephrine;

2011
Dopamine excess in patients with head and neck paragangliomas.
    Anticancer research, 2010, Volume: 30, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Dopamine; Epinephrine; Female; Head and Neck Neoplas

2010
Phaeochromocytoma: a catecholamine and oxidative stress disorder.
    Endocrine regulations, 2011, Volume: 45, Issue:2

    Topics: Adenosine Triphosphate; Adrenal Gland Neoplasms; Catecholamines; Humans; Metanephrine; Multiple Endo

2011
Comparison of plasma metanephrines measured by a commercial immunoassay and urinary catecholamines in the diagnosis of pheochromocytoma.
    Scandinavian journal of clinical and laboratory investigation, 2011, Volume: 71, Issue:8

    Topics: Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Aged, 80 and over; Catecholamines;

2011
Plasma methoxytyramine: a novel biomarker of metastatic pheochromocytoma and paraganglioma in relation to established risk factors of tumour size, location and SDHB mutation status.
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:11

    Topics: Adrenal Gland Neoplasms; Adult; Biomarkers, Tumor; Dopamine; Female; Humans; Male; Middle Aged; Muta

2012
[METANEPHRINE, NORMETANEPHRINE AND METABOLITES OF CATECHOLAMINES].
    Acta Universitatis Carolinae. Medica, 1963, Volume: Suppl 17

    Topics: Catecholamines; Chromatography; Electrophoresis; Epinephrine; Humans; Metanephrine; Normetanephrine;

1963
Pheochromocytoma: recommendations for clinical practice from the First International Symposium. October 2005.
    Nature clinical practice. Endocrinology & metabolism, 2007, Volume: 3, Issue:2

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Biomarkers, Tumor; Child; Humans; Metanephrine; Middle A

2007
[Difficult diagnosis of a pancreatic paraganglioma].
    La Revue de medecine interne, 2007, Volume: 28, Issue:10

    Topics: Adult; Biomarkers, Tumor; Chromogranin A; Diagnosis, Differential; Female; Follow-Up Studies; Humans

2007
[Secreting retroperitoneal paraganglioma. Apropos of a case].
    Journal de chirurgie, 1997, Volume: 134, Issue:5-6

    Topics: Chemotherapy, Adjuvant; Dehydroepiandrosterone; Female; Humans; Metanephrine; Middle Aged; Normetane

1997