Macular Holes

Synonym
Retinal Holes
Macular Holes
Retinal Dialyses
Retinal Breaks
Retinal Tears

Excerpt	Reference
"Vitrectomy for macular holes is often of benefit and patients may recover good visual acuity, especially early in the disease process."	( Cleary, PE; Goggin, M; Minihan, M, 1997)
"Women with macular holes are characterized by lower GH and IGF-1, which prompts further study."	( Kmera-Muszyńska, M; Zgliczyński, W, 2000)
"Macular holes are staged according to the size of the hole and the presence or absence of a posterior vitreous detachment."	( Haritoglou, C, 2007)
"Finding all retinal breaks is a critical step in rhegmatogenous retinal detachment (RRD) surgery in order to prevent persistent/recurrent retinal detachment (RD)."	( Burton, RL; Gupta, D; Ong, J, 2011)
"Retinal tears are commonly found (46%) in the eyes of patients who present with symptoms and signs of acute PVD and VH."	( Cohen, SM; Witmer, MT, 2013)
"Macular holes are a common eye disease that leads to visual impairment."	( Seifi Majdar, R; Shahalinejad, S, 2021)

Excerpt	Reference
"Giant retinal tears have been repaired in six consecutive patients without the use of a scleral buckle."	( Hoffman, ME; Sorr, EM, 1986)
"Idiopathic macular holes have one of two patterns early after surgical closure, simple closure or a bridge formation."	( Kishi, S; Takahashi, H, 2000)
"Macular holes have been described in association with benign vascular tumours of the retina."	( Aylward, GW; Charteris, DH; Clare, G; Yorston, D, 2007)

Excerpt	Reference
"Treatment of isolated macular holes in a flexible retina by silicone vitrectomy achieved a 78."	( Faure, JF; Haut, J; Larricart, P; Le Mer, Y; Monin, C, 1987)
"The standard treatment for retinal breaks is thermal adhesion."	( Barnstable, CJ; Christmas, NJ; Howard, MA; Liggett, PE; Saito, Y; Skolik, SA, 1995)
"Five consecutive patients with giant retinal tears were treated with pneumatic retinopexy using paracentesis and two or more gas injections."	( Irvine, AR; Lahey, JM, 1994)
"To surgically treat patients with macular holes, the authors previously reported both anatomic (re-attachment) and visual success (2 lines of improvement) in a series of 52 eyes."	( Kelly, NE; Novack, GD; Patel, AC; Salzano, TC; Wells, JW; Wendel, RT, 1993)
"Treatment of full-thickness traumatic macular holes with vitrectomy, fluid-gas exchange, and TGF-beta-2 may result in successful anatomic closure and visual improvement."	( Glaser, BM; Murphy, RP; Pappas, SS; Rubin, JS; Sjaarda, RN; Thompson, JT, 1995)
"Fifty-one eyes with chronic macular holes (> or = 2 years' duration) were treated in a retrospective analysis of the results of vitrectomy, 16% perfluoropropane gas tamponade, and one of three adjunctive agents (bovine transforming growth factor beta-2, recombinant transforming growth factor beta-2, or autologous platelet extract)."	( Lansing, MB; Sjaarda, RN; Thompson, JT, 1997)
"One hundred thirty eyes with idiopathic macular holes of 1 year or less and a refracted Early Treatment Diabetic Retinopathy Study visual acuity of 20/80 or worse were treated with 1."	( Abrams, GW; Flynn, HW; Margherio, RR; Sjaarda, RN; Smiddy, WE; Thompson, JT; Williams, GA, 1998)
"Forty-seven eyes with giant retinal tears were treated in a prospective randomized fashion."	( Batman, C; Cekiç, O, 1999)
"The treatment of idiopathic giant retinal tears with vitrectomy and temporary silicone oil tamponade maximizes the functional results and permits the definitive reattachment of the retina in detriment of the classic complications of vitrectomy."	( Donati, G; Kapetanios, AD; Pournaras, CJ, 2000)
"Multiple macular holes may be treated by surgical posterior detachment combined with gas tamponade."	( Hayashi, Y; Miyamoto, T; Ohnishi, Y; Saika, S; Yoshitomi, T, 2002)
"Only the patients with macular holes were treated by fluid-air exchange."	( Hata, N; Kasuga, Y; Lee, S; Manabe, S; Ohashi, H; Takashima, Y; Yamakawa, R, 2004)
"Of the macular holes not treated previously, 81."	( Ding, M; Lambert, HM; Tafoya, ME; Vu, L, 2003)
"In eyes with macular holes surgically repaired with gas tamponade significant improvements in visual acuity are seen more frequently than eyes treated with silicone oil tamponade."	( Ding, M; Lambert, HM; Tafoya, ME; Vu, L, 2003)
"Successfully treated macular holes remained closed at all follow-up points during the study period."	( Gehlbach, PL; Mori, K; Saito, S; Yoneya, S, 2007)
"Twenty highly myopic patients with macular holes and localized posterior RD, treated initially with intravitreal injection of C(3) F(8) , were prospectively studied."	( Chen, FT; Chen, MS; Lin, CP; Yang, CH; Yang, CM; Yeh, PT, 2011)
"Ten eyes had undergone surgery for macular holes, and 6 eyes had been treated for macular pucker."	( Gandorfer, A; Haritoglou, C; Höing, A; Kampik, A; Kohnen, T; Rudolph, G; von Jagow, B, 2009)
"These macular holes can be treated by streamlined surgery, that is, with no internal limiting membrane peeling and no facedown positioning (only avoidance of the supine position) with a closure rate of more than 90% and a mean gain in visual acuity of more than 2 ETDRS lines at 3 months."	( Aout, M; Berrod, JP; Creuzot-Garcher, C; Devin, F; Gaudric, A; Korobelnik, JF; Le Mer, Y; Massin, P; Tadayoni, R; Vicaut, E, 2011)
"To evaluate the closure rate of macular holes in highly myopic eyes treated with the inverted internal limiting membrane flap technique."	( Mateo, C; Oleñik, A; Rios, J, 2016)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	64 (5.58)	23.3326
1990's	156 (13.61)	12.5806
2000's	443 (38.66)	18.1394
2010's	394 (34.38)	28.8240
2020's	89 (7.77)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	1	0
glycine	low	1	0
hydrogen carbonate	low	1	0
nitrates	low	1	0
nitrites	low	2	0
nitrous oxide	low	2	0
uric acid	low	1	0
acetazolamide	medium	5	1
albendazole	low	1	0
apraclonidine	medium	1	1
aspirin	low	1	0
azathioprine	low	1	0
bupivacaine	low	4	0
clonidine	medium	1	1
diclofenac	medium	1	1
erythrosine	low	6	0
fluconazole	low	2	0
foscarnet	low	1	0
gentamicin	medium	3	1
ethidium	low	1	0
hydroxychloroquine	low	1	0
lidocaine	medium	7	1
indomethacin	medium	1	1
2-propanol	low	23	0
ketorolac	low	2	0
memantine	low	1	0
ofloxacin	medium	2	2
probenecid	low	2	0
proxymetacaine	low	1	0
propofol	low	1	0
krypton	medium	2	1
ticlopidine	low	1	0
mitomycin	low	1	0
prednisolone	medium	5	1
thymidine	low	1	0
hydroxyproline	low	1	0
thyroxine	low	1	0
prednisolone acetate	low	1	0
prednisone	low	3	0
fluprednisolone	low	1	0
pilocarpine	low	3	0
chloramphenicol	low	1	0
lysine	low	2	0
adenosine diphosphate	low	1	0
levodopa	low	1	0
tyrosine	low	1	0
adenosine monophosphate	low	1	0
colchicine	low	1	0
fluocinolone acetonide	low	2	0
tryptophan	low	1	0
arginine	low	1	0
perfluoroethane	medium	25	5
perflutren	medium	283	37
triamcinolone acetonide	medium	58	3
methylprednisolone	low	1	0
propoxycaine	low	1	0
penicillanic acid	low	1	0
decalin	low	1	0
quinoxalines	low	1	0
tolonium chloride	low	1	0
thiophenes	medium	4	2
bromphenol blue	low	4	0
sulfan blue	low	3	0
indazoles	low	1	0
cyclopentane	medium	2	1
thiazoles	low	1	0
perfluorodecalin	medium	24	1
perfluorooctane	medium	40	2
perfluorotributylamine	low	2	0
dexamethasone 21-phosphate	low	1	0
betamethasone	low	2	0
perflubron	medium	1	1
fluorometholone	low	1	0
hematoxylin	low	1	0
c.i. 42510	medium	47	7
ethambutol	low	1	0
vancomycin	low	1	0
fluorescein	low	7	0
sulfur hexafluoride	medium	234	20
c.i. direct blue 1	low	2	0
Brilliant Blue	medium	13	4
light green sf	low	1	0
enbucrilate	low	2	0
neodymium	low	4	0
argon	low	4	0
xenon	low	3	0
yttrium	low	1	0
deuterium oxide	low	1	0
trolamine salicylate	low	4	0
fluorides	low	10	0
daunorubicin	medium	1	1
phosphotyrosine	low	1	0
phenyl acetate	low	4	0
triamcinolone	medium	10	1
glutamic acid	low	2	0
timolol	medium	4	2
tobramycin	low	1	0
paclitaxel	low	1	0
substance p	low	1	0
propiconazole	low	14	0
piperacillin	low	1	0
fomesafen	low	1	0
clopidogrel	low	1	0
bromfenac	medium	1	1
thiazolyl blue	low	1	0
betamethasone sodium phosphate	low	1	0
6-carboxyfluorescein	low	1	0
perfluorophenanthrene	medium	4	2
ketorolac tromethamine	low	1	0
nsc-172755	low	1	0
fibrinogen	medium	7	1
homocysteine	low	1	0
bosentan anhydrous	low	1	0
cyanates	low	1	0
betamethasone acetate phosphate	low	1	0
imatinib mesylate	low	1	0
triiodothyronine	low	1	0
beta-lactams	low	1	0
levofloxacin	medium	2	2
nepafenac	medium	1	1
atropine	low	1	0
ropivacaine	low	1	0
dabigatran	low	1	0
lenalidomide	low	1	0
calcein am	low	1	0
genipin	low	1	0
difluprednate	low	1	0
iridoids	low	1	0
melphalan	low	1	0
bromochloroacetic acid	low	7	0
digoxin	low	1	0
tamoxifen	low	5	0
nitinol	low	1	0
dinoprostone	medium	2	1
11-cis-retinal	low	2	0
zeaxanthin	low	2	0
lutein	medium	4	1
acetylspiramycin	low	1	0
dorzolamide	medium	3	1
aluminum	low	2	0
carbocyanines	low	1	0
coomassie brilliant blue	medium	42	7
g(m1) ganglioside	low	1	0
pazopanib	low	1	0
brimonidine tartrate	medium	2	1
carfilzomib	low	1	0
losartan potassium	low	4	0
indocyanine green	medium	250	18
ethidium homodimer	low	1	0
acid phosphatase	low	1	0
jaw	low	1	0
endothelin-1	low	2	0
calpain	low	1	0
chitosan	low	1	0
perfluorobutylpentane	medium	1	1
piperacillin, tazobactam drug combination	low	1	0
interleukin-8	low	4	0
vasoactive intestinal peptide	low	1	0
heme	low	1	0
ascorbic acid	low	1	0
warfarin	low	1	0
almagate	medium	10	1
dorzolamide-timolol combination	medium	1	1
epidermal growth factor	low	1	0
transforming growth factor beta	medium	31	6
hyaluronoglucosaminidase	low	1	0
adrenomedullin	low	1	0
cyclosporine	low	2	0
thromboplastin	low	1	0
chondroitin sulfates	low	3	0
exudates	low	1	0
acyclovir	low	4	0
folic acid	low	1	0
ganciclovir	medium	5	1
trypan blue	medium	46	7
cyanine dye 3	low	1	0
eye	medium	50	1
carbidopa	low	1	0

Protein Targets (1,847)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, Retinaldehyde-binding protein 1	0	0	1	1
Chain A, Retinaldehyde-binding protein 1	0	0	1	1
hypoxia-inducible factor 1 alpha subunit	12	0	0	12
RAR-related orphan receptor gamma	35	0	0	35
GLI family zinc finger 3	43	0	0	43
AR protein	61	0	0	61
aldehyde dehydrogenase 1 family, member A1	18	0	0	18
retinoic acid nuclear receptor alpha variant 1	40	0	0	40
retinoid X nuclear receptor alpha	28	0	0	28
estrogen nuclear receptor alpha	58	0	0	58
peroxisome proliferator-activated receptor delta	19	0	0	19
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	39	0	0	39
activating transcription factor 6	16	0	0	16
v-jun sarcoma virus 17 oncogene homolog (avian)	18	0	0	18
Histone H2A.x	17	0	0	17
thyroid hormone receptor beta isoform a	13	0	0	13
heat shock protein beta-1	15	0	0	15
nuclear factor erythroid 2-related factor 2 isoform 1	30	0	0	30
lamin isoform A-delta10	30	0	0	30
Voltage-dependent calcium channel gamma-2 subunit	27	0	0	27
Glutamate receptor 2	27	2	1	30
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	13	0	0	13
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	12	0	0	12
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	2	0	2
thioredoxin reductase	26	0	0	26
GALC protein	1	0	0	1
nuclear receptor subfamily 1, group I, member 3	27	0	0	27
cytochrome P450 family 3 subfamily A polypeptide 4	30	0	0	30
glucocorticoid receptor [Homo sapiens]	49	0	0	49
estrogen-related nuclear receptor alpha	49	0	0	49
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
arylsulfatase A	14	0	0	14
Carbonic anhydrase	0	2	0	2
euchromatic histone-lysine N-methyltransferase 2	35	0	0	35
Bloom syndrome protein isoform 1	15	0	0	15
geminin	31	0	0	31
peripheral myelin protein 22	14	0	0	14
survival motor neuron protein isoform d	7	0	0	7
muscleblind-like protein 1 isoform 1	6	0	0	6
Gamma-aminobutyric acid receptor subunit pi	15	5	2	22
ATP-binding cassette sub-family C member 3	0	32	0	32
Multidrug resistance-associated protein 4	0	32	0	34
Carbonic anhydrase	0	2	0	2
Solute carrier family 22 member 6	0	4	0	5
Carbonic anhydrase 12	0	4	1	11
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Bile salt export pump	0	44	0	44
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Carbonic anhydrase 1	0	15	1	26
Carbonic anhydrase 2	0	16	2	26
Carbonic anhydrase 2	0	2	0	2
Cytochrome P450 1A2	0	1	0	1
Carbonic anhydrase 3	0	3	1	10
Cathepsin B	0	1	0	1
Cytochrome P450 3A4	0	10	1	13
Steryl-sulfatase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	3
Cytochrome P450 2C8	0	3	0	4
Cytochrome P450 2D6	0	4	0	4
Cytochrome P450 2A6	0	2	1	3
Cytochrome P450 2C9	0	9	0	10
5-hydroxytryptamine receptor 2A	0	2	0	2
Androgen receptor	0	9	0	9
Gamma-aminobutyric acid receptor subunit beta-1	15	5	2	22
Translocator protein	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	15	5	2	22
Gamma-aminobutyric acid receptor subunit gamma-2	15	5	3	23
Gamma-aminobutyric acid receptor subunit alpha-5	15	5	2	22
Gamma-aminobutyric acid receptor subunit alpha-3	15	5	2	22
Cannabinoid receptor 1	0	1	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Cytochrome P450 2B6	0	5	1	6
Carbonic anhydrase 4	0	10	1	16
Carbonic anhydrase 6	0	3	1	9
Gamma-aminobutyric acid receptor subunit gamma-1	15	5	2	22
Gamma-aminobutyric acid receptor subunit alpha-2	15	5	2	22
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Adenosine receptor A1	0	3	0	5
Serum paraoxonase/arylesterase 1	0	3	0	3
Dipeptidyl peptidase 4	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	15	5	2	22
Gamma-aminobutyric acid receptor subunit gamma-3	15	5	2	22
Endochitinase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	15	5	2	22
Adenosine receptor A2a	0	3	2	7
5-hydroxytryptamine receptor 2B	0	2	0	2
Sodium-dependent serotonin transporter	0	3	0	3
Delta-type opioid receptor	0	3	1	4
Cytochrome P450 2C19	0	4	0	4
Delta-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	2	0	2
Carbonic anhydrase 5A, mitochondrial	0	4	1	11
Carbonic anhydrase	0	6	0	9
Kappa-type opioid receptor	0	1	0	2
Carbonic anhydrase 7	0	4	1	10
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	1	1	0	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	2	0	5
D(2) dopamine receptor	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-1	15	6	3	24
Gamma-aminobutyric acid receptor subunit beta-3	15	5	2	22
Gamma-aminobutyric acid receptor subunit beta-2	15	5	3	23
Cholinesterase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Mu-type opioid receptor	0	4	0	4
Fatty-acid amide hydrolase 1	0	6	0	6
Beta-carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	7	2	12
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Carbonic anhydrase 9	0	9	1	16
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	2	0	5
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	2	0	6
Carbonic anhydrase	0	2	0	6
Carbonic anhydrase	0	2	0	2
Sigma intracellular receptor 2	0	2	0	2
Delta carbonic anhydrase	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	1	0	1
Renin	0	1	0	1
Carbonic anhydrase	0	2	0	5
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	3	1	5
GABA theta subunit	15	5	2	22
Canalicular multispecific organic anion transporter 1	0	30	0	30
Carbonic anhydrase 4	0	5	0	5
Carbonic anhydrase 15	0	7	0	11
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	3	0	7
Carbonic anhydrase 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	15	5	2	22
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 14	0	3	1	10
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	3	1	10
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	11	0	0	11
Chain B, HADH2 protein	11	0	0	11
Chain A, ATP-DEPENDENT DNA HELICASE Q1	8	0	0	8
Chain A, Ferritin light chain	14	0	0	14
Thymidine kinase	0	3	0	4
phosphopantetheinyl transferase	14	0	0	14
GLS protein	15	0	0	15
TDP1 protein	42	0	0	42
Smad3	10	0	0	10
thyroid stimulating hormone receptor	13	0	0	13
EWS/FLI fusion protein	23	0	0	23
hemoglobin subunit beta	2	0	0	2
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
Solute carrier family 22 member 1	0	5	0	9
Bile salt export pump	0	9	0	9
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	2	0	5
POU domain, class 2, transcription factor 2	0	0	0	2
Cytochrome P450 2J2	0	5	0	5
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
Purine nucleoside phosphorylase	0	0	2	2
Solute carrier family 22 member 6	0	4	0	8
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	4	0	6
Thymidine kinase	0	1	0	2
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
regulator of G-protein signaling 4	13	0	0	13
HPr kinase/phosphorylase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	5	5
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-alpha	0	1	2	4
Heat shock protein HSP 90-beta	0	1	1	3
2-dehydropantoate 2-reductase	0	2	2	4
Heat shock 70 kDa protein 1A	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Heat shock cognate 71 kDa protein	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Endoplasmin	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	1	0	1
Mu-type opioid receptor	0	2	1	3
Delta-type opioid receptor	0	4	1	5
Kappa-type opioid receptor	0	2	1	3
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	2	2
Phosphatidylinositol 4-kinase alpha	0	2	0	2
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	2	2
P2Y purinoceptor 1	0	0	2	2
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	5	0	0	5
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	2
P2Y purinoceptor 11	0	0	2	2
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	2
P2Y purinoceptor 12	0	2	1	3
Sensor protein kinase WalK	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	2	3	5
P2X purinoceptor 2	0	0	1	1
Chain A, Glycogen Phosphorylase B	0	0	1	1
Chain B, Glycogen Phosphorylase B	0	0	1	1
Chain A, ADP-dependent glucokinase	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, phosphodiesterase-nucleotide pyrophosphatase	0	1	0	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain B, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	1	1
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
L-lactate dehydrogenase A chain	0	1	1	2
Adenylate kinase isoenzyme 1	0	0	0	1
Fructose-1,6-bisphosphatase 1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	2
Fructose-1,6-bisphosphatase 1	0	1	0	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	4	3	8
Amine oxidase [flavin-containing] B	0	1	0	1
5'-nucleotidase	0	0	0	1
Choline O-acetyltransferase	0	1	0	1
Adenylate kinase 2, mitochondrial	0	1	0	2
GTP:AMP phosphotransferase AK3, mitochondrial	0	0	0	1
Adenosine receptor A1	0	2	1	3
Adenylate kinase isoenzyme 1	0	1	0	2
5'-AMP-activated protein kinase subunit gamma-1	0	0	5	5
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	1	4	5
Adenylate kinase 2, mitochondrial	0	0	3	4
Glycine--tRNA ligase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	1	5	6
Adenosine deaminase-like protein	0	0	0	1
Protease	0	2	1	3
Histamine H3 receptor	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	4	4
5'-AMP-activated protein kinase subunit beta-1	0	0	2	2
ATP-dependent phosphofructokinase	14	0	0	14
Luciferase	19	0	0	19
glp-1 receptor, partial	9	0	0	9
ATAD5 protein, partial	11	0	0	11
Fumarate hydratase	13	0	0	13
caspase 7, apoptosis-related cysteine protease	10	0	0	10
progesterone receptor	30	0	0	30
farnesoid X nuclear receptor	20	0	0	20
pregnane X nuclear receptor	36	0	0	36
polyprotein	13	0	0	13
67.9K protein	11	0	0	11
peroxisome proliferator activated receptor gamma	26	0	0	26
vitamin D (1,25- dihydroxyvitamin D3) receptor	27	0	0	27
caspase-3	10	0	0	10
IDH1	16	0	0	16
aryl hydrocarbon receptor	25	0	0	25
nuclear receptor subfamily 1, group I, member 2	15	0	0	15
cellular tumor antigen p53 isoform a	8	0	0	8
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
chromobox protein homolog 1	21	0	0	21
nuclear factor erythroid 2-related factor 2 isoform 2	16	0	0	16
transcriptional regulator ERG isoform 3	5	0	0	5
thyroid hormone receptor beta isoform 2	35	0	0	35
histone deacetylase 9 isoform 3	6	0	0	6
mitogen-activated protein kinase 1	6	0	0	6
urokinase-type plasminogen activator precursor	5	0	0	5
plasminogen precursor	5	0	0	5
urokinase plasminogen activator surface receptor precursor	5	0	0	5
Vif	0	1	0	2
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	1	0	2
neuropeptide S receptor isoform A	5	0	0	5
Interferon beta	30	0	0	30
Cellular tumor antigen p53	35	0	0	35
Integrin beta-3	6	2	1	9
Integrin alpha-IIb	6	1	1	8
Methionine aminopeptidase	0	1	0	1
ATPase family AAA domain-containing protein 5	21	0	0	21
Ataxin-2	22	0	0	22
glucocerebrosidase	8	0	0	8
DNA polymerase kappa isoform 1	14	0	0	14
histone acetyltransferase KAT2A isoform 1	10	0	0	10
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	3	1	4
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	4	0	4
Type-1 angiotensin II receptor	0	2	2	4
Type-2 angiotensin II receptor	0	3	0	3
Type-2 angiotensin II receptor	0	2	0	2
NFKB1 protein, partial	5	0	0	5
muscarinic acetylcholine receptor M1	10	0	0	10
Alpha-2A adrenergic receptor	0	10	2	12
Alpha-2B adrenergic receptor	0	8	3	11
Alpha-2C adrenergic receptor	0	7	2	9
Alpha-2B adrenergic receptor	0	4	0	4
Alpha-1D adrenergic receptor	0	9	2	11
Adenosine receptor A2b	0	0	2	2
Alpha-1A adrenergic receptor	0	2	2	4
Alpha-1B adrenergic receptor	0	2	2	4
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	24	0	0	24
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
alpha-galactosidase	4	0	0	4
cytochrome P450 2C19 precursor	6	0	0	6
flap endonuclease 1	10	0	0	10
DNA polymerase iota isoform a (long)	19	0	0	19
lethal factor (plasmid)	10	0	0	10
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	1	0	2
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
Chain A, Hyaluronidase, phage associated	0	1	0	1
acetylcholinesterase	15	0	0	15
thioredoxin glutathione reductase	9	0	0	9
lethal(3)malignant brain tumor-like protein 1 isoform I	3	0	0	3
Polyphenol oxidase 2	0	1	0	3
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Spike glycoprotein	16	0	2	18
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, 2-oxoglutarate Oxygenase	12	0	0	12
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	8	0	0	8
hypothetical protein, conserved	4	0	0	4
cytochrome P450 2D6	18	0	0	18
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 1	0	3	0	4
Prostaglandin G/H synthase 2	0	2	0	3
Epidermal growth factor receptor	0	7	3	10
Fatty acid-binding protein, liver	0	4	0	4
Myeloperoxidase	0	2	0	2
Prostaglandin G/H synthase 1	0	4	0	5
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	8	0	8
Substance-P receptor	0	4	0	4
Prostaglandin G/H synthase 2	0	9	4	13
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	9	1	1	11
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	4	0	4
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	7	1	8
Sigma non-opioid intracellular receptor 1	0	0	1	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	4	0	0	4
short transient receptor potential channel 6 isoform 1	0	0	1	1
5-hydroxytryptamine receptor 4	0	6	0	6
Muscarinic acetylcholine receptor M2	0	7	2	12
Muscarinic acetylcholine receptor M4	0	5	1	8
Muscarinic acetylcholine receptor M1	0	5	1	9
Muscarinic acetylcholine receptor M3	0	4	1	8
Muscarinic acetylcholine receptor M4	0	4	1	8
Muscarinic acetylcholine receptor M5	0	4	1	8
Muscarinic acetylcholine receptor M5	0	6	1	9
Muscarinic acetylcholine receptor M2	0	4	1	9
Muscarinic acetylcholine receptor M1	0	6	3	12
Muscarinic acetylcholine receptor M1	0	0	1	2
Muscarinic acetylcholine receptor M3	0	5	1	8
5-hydroxytryptamine receptor 2C	0	7	0	7
Muscarinic acetylcholine receptor M4	0	1	0	1
Histamine H2 receptor	9	0	0	10
5-hydroxytryptamine receptor 7	0	3	0	3
Reverse transcriptase/RNaseH	0	4	1	6
Muscarinic acetylcholine receptor	0	1	1	2
SMAD family member 2	13	0	0	13
SMAD family member 3	13	0	0	13
Microtubule-associated protein tau	10	0	0	10
G	17	0	0	17
P53	1	0	0	1
thyroid stimulating hormone receptor	15	0	0	15
peripheral myelin protein 22 isoform 1	4	0	0	4
cytochrome P450 3A4 isoform 1	15	0	0	15
M-phase phosphoprotein 8	5	0	0	5
HLA class I histocompatibility antigen, B alpha chain	17	0	0	17
Inositol hexakisphosphate kinase 1	17	0	0	17
Protein-arginine deiminase type-4	0	1	0	1
cytochrome P450 2C9, partial	17	0	0	17
pregnane X receptor	5	0	0	5
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	16	2	23
Glycine receptor subunit alpha-1	0	16	0	16
Glycine receptor subunit beta	0	16	0	16
Glycine receptor subunit alpha-2	0	16	0	16
Glycine receptor subunit alpha-3	0	16	0	16
ORF73	0	0	1	1
estrogen receptor 2 (ER beta)	16	0	0	16
vitamin D3 receptor isoform VDRA	11	0	0	11
nuclear receptor ROR-gamma isoform 1	13	0	0	13
Nuclear receptor subfamily 1 group I member 2	0	0	5	5
Endothelin receptor type B	1	1	0	2
Endothelin receptor type B	0	2	1	3
Endothelin-1 receptor	0	3	0	3
Endothelin-1 receptor	1	2	1	4
Endothelin receptor type B	0	0	1	1
Deoxyhypusine synthase	0	1	0	1
Sodium/bile acid cotransporter	0	2	0	2
Endothelin-1 receptor	0	1	0	1
Pannexin-1	0	2	0	2
Potassium channel subfamily K member 3	0	3	0	3
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	1	2
Potassium channel subfamily K member 9	0	1	0	1
Vesicular glutamate transporter 3	0	1	0	1
Proteasome subunit beta type-11	0	1	0	1
PPM1D protein	12	0	0	12
Caspase-7	4	0	0	4
caspase-3	4	0	0	4
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Cathepsin B	0	1	0	1
Cathepsin G	0	1	0	1
Lysosomal protective protein	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Proteasome subunit beta type-1	0	1	0	1
Proteasome subunit beta type-2	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	1
Proteasome subunit alpha type-2	0	1	0	1
Proteasome subunit alpha type-3	0	1	0	1
Proteasome subunit alpha type-4	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	1
Proteasome subunit alpha type-5	0	1	0	1
Proteasome subunit beta type-4	0	1	0	1
Proteasome subunit beta type-6	0	1	0	1
Proteasome subunit beta type-5	0	1	0	1
26S proteasome regulatory subunit 7	0	1	0	1
Proteasome subunit beta type-1	0	1	0	1
Proteasome subunit beta type-10	0	1	0	1
26S proteasome regulatory subunit 6B	0	1	3	4
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	1
Proteasome subunit beta type-2	0	1	0	1
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	0	1
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Glutathione S-transferase omega-1	0	2	0	2
Potassium voltage-gated channel subfamily H member 2	0	10	0	10
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
Proteasome subunit alpha-type 8	0	1	0	1
Proteasome subunit beta type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	10	0	0	10
streptokinase A precursor	0	0	4	4
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Chain A, Cruzipain	6	0	0	6
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	15	0	0	15
Beta-1 adrenergic receptor	0	0	2	2
Alpha-1B adrenergic receptor	0	0	1	1
cytochrome P450 2D6 isoform 1	8	0	0	8
cytochrome P450 2C9 precursor	4	0	0	4
Membrane primary amine oxidase	0	1	0	1
5-hydroxytryptamine receptor 3A	0	0	1	1
Solute carrier family 22 member 3	0	3	0	3
5-hydroxytryptamine receptor 1A	0	2	0	2
Alpha-1B adrenergic receptor	0	4	0	4
Alpha-1A adrenergic receptor	0	0	1	1
D	0	1	0	1
D(3) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	6	1	7
Amine oxidase [flavin-containing] A	0	2	0	2
Alpha-2C adrenergic receptor	0	3	0	3
Alpha-2A adrenergic receptor	0	3	0	3
Alpha-1D adrenergic receptor	0	2	0	2
D(1B) dopamine receptor	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
5-hydroxytryptamine receptor 1B	0	6	0	6
Alpha-2B adrenergic receptor	0	0	0	1
D(4) dopamine receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	4	1	5
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Nischarin	0	2	0	2
Solute carrier family 22 member 1	0	2	0	2
Multidrug and toxin extrusion protein 1	0	6	0	6
Nischarin	0	1	0	1
nonstructural protein 1	3	0	0	3
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	5	0	0	5
Liver carboxylesterase 1	0	0	0	1
Sodium-dependent serotonin transporter	0	4	0	4
Rap guanine nucleotide exchange factor 4	1	0	0	1
P2Y purinoceptor 12	0	1	0	1
endonuclease IV	2	0	0	2
PAX8	0	0	0	2
USP1 protein, partial	16	0	0	16
Thrombopoietin	1	0	0	1
nuclear receptor subfamily 0 group B member 1	0	1	0	1
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
ras-related protein Rab-9A	6	0	0	6
steroidogenic factor 1	0	1	0	1
caspase-1 isoform alpha precursor	1	0	0	1
Tubulin alpha-1A chain	0	2	2	5
Tubulin beta chain	0	2	2	4
Plasma kallikrein	0	0	0	4
Tubulin beta-4A chain	0	4	3	9
ATP-dependent translocase ABCB1	0	3	0	3
Tubulin beta chain	0	4	3	9
ATP-dependent translocase ABCB1	0	8	1	15
Tubulin alpha-3C chain	0	4	3	9
Serine/threonine-protein kinase pim-1	0	1	3	4
ATP-dependent translocase ABCB1	0	4	0	4
Tubulin alpha-1B chain	0	4	3	9
Tubulin alpha-4A chain	0	4	3	9
Tubulin beta-4B chain	0	4	3	9
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	5	3	10
Tubulin beta-2A chain	0	4	3	9
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	4	3	9
Tubulin beta-2B chain	0	2	1	5
Tubulin alpha-3E chain	0	4	3	9
Tubulin alpha-1A chain	0	4	3	9
Similar to alpha-tubulin isoform 1	0	1	1	4
Similar to alpha-tubulin isoform 1	0	1	0	3
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	4	3	9
Tubulin beta-6 chain	0	4	3	9
Tubulin beta-2B chain	0	4	3	9
Tubulin beta-1 chain	0	4	3	9
Solute carrier family 22 member 2	0	1	0	3
Prothrombin	0	2	1	3
Coagulation factor X	0	1	0	1
Plasminogen	0	1	0	1
Coagulation factor XII	0	1	0	1
Tissue-type plasminogen activator	0	1	0	1
Vitamin K-dependent protein C	0	1	0	1
Serine protease hepsin	0	1	0	1
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	3	5
Trypsin-3	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	8	0	0	8
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
huntingtin isoform 2	5	0	0	5
histone-lysine N-methyltransferase 2A isoform 2 precursor	5	0	0	5
Polyunsaturated fatty acid lipoxygenase ALOX15B	5	0	0	5
Transthyretin	0	2	1	6
NADH-ubiquinone oxidoreductase chain 4	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
DNA topoisomerase 2-alpha	0	0	3	4
Carbonyl reductase [NADPH] 1	0	0	0	1
Glutamate receptor 1	1	2	1	4
Glutamate receptor 3	1	2	1	4
Glutamate receptor 4	1	2	1	4
Platelet-activating factor receptor	1	0	0	1
Multidrug resistance-associated protein 1	0	3	0	4
Histone deacetylase 1	0	3	0	3
Histone deacetylase 8	0	3	0	3
Histone deacetylase 6	0	3	0	3
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	4
Aldo-keto reductase family 1 member B10	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	2	0	4
Transient receptor potential cation channel subfamily A member 1	0	0	2	2
Dihydrofolate reductase	0	3	0	3
Cytochrome c oxidase subunit 2	0	2	0	2
Albumin	0	3	6	9
Interleukin-8	0	2	0	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Fatty acid-binding protein, intestinal	0	2	1	3
Aldo-keto reductase family 1 member B1	0	3	0	3
UDP-glucuronosyltransferase 2B7	0	2	0	3
UDP-glucuronosyltransferase 1-6	0	4	0	4
UDP-glucuronosyltransferase 1A1	0	5	0	5
UDP-glucuronosyltransferase 1A4	0	2	0	3
Sodium- and chloride-dependent GABA transporter 1	0	4	0	4
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	4	0	4
Sodium- and chloride-dependent GABA transporter 3	0	4	0	4
Prostaglandin G/H synthase 2	0	3	0	3
UDP-glucuronosyltransferase 1A3	0	0	0	1
UDP-glucuronosyltransferase 2B10	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	4	0	4
Prostaglandin G/H synthase 2	0	2	0	3
Prostaglandin G/H synthase 1	0	3	0	3
UDP-glucuronosyltransferase 1A7	0	2	0	2
UDP-glucuronosyltransferase 1A10	0	2	0	2
importin subunit beta-1 isoform 1	3	0	0	3
snurportin-1	3	0	0	3
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
STAT3, partial	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	4	0	0	4
tumor necrosis factor	1	0	0	1
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	3	0	5
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Replicase polyprotein 1ab	0	2	2	4
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Solute carrier organic anion transporter family member 1B3	0	7	0	8
Solute carrier organic anion transporter family member 1B1	0	7	0	9
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 7	0	1	0	3
Prostaglandin E2 receptor EP2 subtype	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 11	0	2	0	3
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier family 22 member 7	0	2	0	3
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Androgen receptor	0	3	1	4
Genome polyprotein	0	2	1	3
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	7	0	0	7
thyrotropin-releasing hormone receptor	3	0	0	3
eyes absent homolog 2 isoform a	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
Flavin reductase (NADPH)	0	0	1	1
large T antigen	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	2
Pantothenate synthetase	0	1	0	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
apical membrane antigen 1, AMA1	6	0	0	6
unnamed protein product	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	2
bcl-2-like protein 11 isoform 1	0	0	1	1
Histone deacetylase 3	0	2	0	2
Rap guanine nucleotide exchange factor 3	3	0	0	3
Chymotrypsinogen A	0	2	0	2
Beta-lactamase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Heme oxygenase 1	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	1	2
Aromatase	0	3	0	3
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Heme oxygenase 2	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Histone deacetylase 4	0	2	0	2
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
TAR DNA-binding protein 43	7	0	0	7
Lanosterol 14-alpha demethylase	0	2	1	3
Sterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	1	2
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	2	0	2
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
14-alpha sterol demethylase	0	0	1	1
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
heat shock protein 90, putative	0	0	0	2
likely tRNA 2'-phosphotransferase	0	1	0	1
lysosomal alpha-glucosidase preproprotein	3	0	0	3
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
Neuronal acetylcholine receptor subunit alpha-4	1	1	0	2
Neuronal acetylcholine receptor subunit beta-2	1	1	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Chain A, Dihydrofolate reductase	0	0	1	1
acid sphingomyelinase	1	0	0	1
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	1	0	2
Dihydrofolate reductase	0	0	1	1
Alpha-synuclein	4	1	0	5
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	2	0	3
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Chain A, probable fosfomycin resistance protein	0	0	1	1
Chain B, probable fosfomycin resistance protein	0	0	1	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	0	1
DNA polymerase delta catalytic subunit	0	1	0	1
Gamma-aminobutyric acid	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
D(1A) dopamine receptor	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	2	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	2	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit delta	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	2	2	4
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	2	3
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	2	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	2	3
Gamma-aminobutyric acid receptor subunit beta-2	0	1	2	3
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	2	3
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	2	3
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
ClpP	1	0	0	1
Transitional endoplasmic reticulum ATPase	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 2	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 11	0	1	0	2
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Excitatory amino acid transporter 4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Glutathione reductase, mitochondrial	0	4	0	4
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, NMDA 1	0	6	2	11
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Glutamate receptor ionotropic, NMDA 2A	0	6	2	11
Glutamate receptor ionotropic, NMDA 2C	0	6	2	11
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	3	0	3
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	3	0	3
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	4
Glutamate receptor ionotropic, NMDA 2D	0	6	2	11
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	6	2	11
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	6	2	11
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	4	0	4
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Chain E, Fibrin beta chain	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	6	0	0	6
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
15-lipoxygenase, partial	4	0	0	4
WRN	2	0	0	2
Mcl-1	0	1	0	1
MPI protein	0	1	0	1
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0	0	0	1
alkaline phosphatase, intestinal	0	0	1	1
luciferase	1	0	0	1
pyruvate kinase	2	0	0	2
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
CDK5	0	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
major prion protein preproprotein Prp precursor	0	1	0	1
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	0	1	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
intestinal alkaline phosphatase precursor	0	0	1	1
serine/threonine-protein kinase PLK1	2	0	0	2
DNA polymerase eta isoform 1	4	0	0	4
Tat	0	1	0	1
alkaline phosphatase, germ cell type preproprotein	0	0	1	1
endoribonuclease toxin MazF	0	0	1	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Pyruvate kinase PKM	0	1	0	1
phosphoglycerate kinase	3	0	0	3
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Spike glycoprotein	0	0	2	2
Replicase polyprotein 1ab	0	1	2	3
Transmembrane protease serine 2	0	0	2	2
Procathepsin L	0	1	2	3
Replicase polyprotein 1a	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Replicase polyprotein 1ab	0	1	2	3
Sigma intracellular receptor 2	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Angiotensin-converting enzyme 2	0	0	2	2
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
serine/threonine-protein kinase mTOR isoform 1	4	0	0	4
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Tyrosine-protein kinase ABL1	0	6	5	12
Mast/stem cell growth factor receptor Kit	0	6	4	10
Breakpoint cluster region protein	0	1	5	7
Platelet-derived growth factor receptor alpha	0	5	4	9
Cytochrome P450 3A5	0	0	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
DNA repair and recombination protein RadA	0	0	1	1
Cyclin-dependent kinase 1	0	1	3	4
G2/mitotic-specific cyclin-B1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	1	4
Cyclin-A2	0	1	0	1
Cyclin-dependent kinase 2	0	3	3	6
RAC-alpha serine/threonine-protein kinase	0	2	3	5
Cyclin-A1	0	1	0	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Parkin	2	0	0	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
Prostaglandin E synthase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	4	0	4
Phospholipase A2, major isoenzyme	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Thromboxane-A synthase	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Caspase-1	0	2	0	3
Bifunctional epoxide hydrolase 2	0	3	0	3
Peroxisome proliferator-activated receptor gamma	0	0	3	3
Aldo-keto reductase family 1 member C3	0	2	0	2
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Guanine nucleotide-binding protein G	3	0	0	3
Prostaglandin D2 receptor	0	2	0	2
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Caspase-3	0	1	0	1
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Caspase-9	0	1	0	1
Cell division control protein 42 homolog	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	1	3	4
Cereblon isoform 4	0	1	0	1
Bromodomain-containing protein 4	0	1	0	1
DNA-binding protein Ikaros	0	0	1	3
DNA damage-binding protein 1	0	1	0	1
Protein cereblon	0	2	1	5
Zinc finger protein Aiolos	0	0	1	1
dopamine D1 receptor	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Tyrosine-protein kinase Lck	0	4	3	8
Tyrosine-protein kinase Fyn	0	3	3	6
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
Solute carrier family 15 member 1	0	2	0	2
SLC16A10 protein	0	0	0	3
Monocarboxylate transporter 10	0	0	0	3
CAAX prenyl protease 2 isoform 2	0	0	0	1
DNA gyrase subunit A	0	3	0	4
DNA primase	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
retinoic acid receptor alpha isoform 1	0	1	0	1
retinoic acid receptor RXR-alpha isoform a	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	4	0	0	4
Large neutral amino acids transporter small subunit 1	0	1	0	1
Acetylcholinesterase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Acetylcholinesterase	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Sodium/iodide cotransporter	0	1	0	1
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
Trypsin	0	0	0	1
DNA gyrase subunit A	0	1	0	2
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit B	0	2	0	3
Genome polyprotein	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	3	3	6
Integrin alpha-V	0	1	0	1
60 kDa chaperonin	0	1	0	1
Botulinum neurotoxin type A	0	1	0	1
Apoptosis regulator Bcl-2	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	3	0	3
Fibroblast growth factor receptor 1	0	4	3	7
Substance-K receptor	0	6	0	6
Cholecystokinin receptor type A	0	2	0	2
Melanocortin receptor 5	0	4	0	4
10 kDa heat shock protein, mitochondrial	0	3	0	3
Bcl-2-like protein 1	0	1	0	1
Tyrosine-protein kinase Mer	0	2	3	5
Thiosulfate sulfurtransferase	0	3	0	3
Beta-tubulin	0	1	0	1
60 kDa chaperonin	0	3	0	3
10 kDa chaperonin	0	3	0	3
Nucleotide-binding oligomerization domain-containing protein 2	0	1	0	1
Leukotriene C4 synthase	0	0	3	3
tyrosine-protein kinase Yes	3	0	0	3
Bone morphogenetic protein receptor type-1B	0	0	3	3
Membrane-associated progesterone receptor component 1	0	0	3	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	2	3	5
Serine/threonine-protein kinase PLK4	0	2	3	5
Serine/threonine-protein kinase 25	0	0	3	3
ATP-dependent RNA helicase DDX3X	0	0	3	3
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	3	3
Pyridoxal kinase	0	0	3	3
Citron Rho-interacting kinase	0	0	3	3
Serine/threonine-protein kinase RIO3	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 7	0	0	3	3
Serine/threonine-protein kinase Chk1	0	1	3	4
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	3	3
Peripheral plasma membrane protein CASK	0	0	3	3
Aurora kinase A	0	2	3	5
Cyclin-G-associated kinase	0	0	3	3
Serine/threonine-protein kinase DCLK1	0	0	3	3
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	3	3
Muscle, skeletal receptor tyrosine-protein kinase	0	0	3	3
Ephrin type-B receptor 6	0	0	3	3
Peroxisomal acyl-coenzyme A oxidase 3	0	0	3	3
Mitogen-activated protein kinase 13	0	0	3	3
3-phosphoinositide-dependent protein kinase 1	0	0	3	3
Mitogen-activated protein kinase kinase kinase 13	0	0	3	3
Death-associated protein kinase 3	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 2	0	1	3	4
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	3	3
NUAK family SNF1-like kinase 1	0	1	3	4
Dynamin-like 120 kDa protein, mitochondrial	0	0	3	3
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	3	3
Tyrosine-protein kinase JAK2	0	0	3	3
Rho-associated protein kinase 2	0	0	3	3
Serine/threonine-protein kinase ULK1	0	0	3	3
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	3	3
Ribosomal protein S6 kinase alpha-5	0	0	3	3
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	3	3
Ribosomal protein S6 kinase alpha-4	0	0	3	3
Serine/threonine-protein kinase 16	0	0	3	3
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	3	3
Serine/threonine-protein kinase PAK 3	0	0	3	3
Cyclin-dependent kinase-like 5	0	0	3	3
Serine/threonine-protein kinase 17B	0	0	3	3
Serine/threonine-protein kinase 10	0	0	3	3
Serine/threonine-protein kinase D3	0	1	3	4
Cyclin-dependent kinase 14	0	0	3	3
Structural maintenance of chromosomes protein 2	0	0	3	3
Mitogen-activated protein kinase kinase kinase 6	0	0	3	3
Serine/threonine-protein kinase OSR1	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	3	3
Serine/threonine-protein kinase LATS1	0	0	3	3
Serine/threonine-protein kinase PAK 4	0	2	3	5
Serine/threonine-protein kinase Chk2	0	1	3	4
RAF proto-oncogene serine/threonine-protein kinase	0	3	3	6
High affinity nerve growth factor receptor	0	0	3	3
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	2	2
ADP/ATP translocase 2	0	0	3	3
Protein kinase C beta type	0	1	3	4
Insulin receptor	0	2	3	5
Glycogen phosphorylase, liver form	0	0	3	3
Tyrosine-protein kinase Fes/Fps	0	0	3	3
Macrophage colony-stimulating factor 1 receptor	0	3	3	6
Tyrosine-protein kinase Yes	0	0	3	3
Tyrosine-protein kinase Lyn	0	0	3	3
Proto-oncogene tyrosine-protein kinase receptor Ret	0	3	3	6
Insulin-like growth factor 1 receptor	0	0	3	3
Signal recognition particle receptor subunit alpha	0	0	2	2
Cytochrome c1, heme protein, mitochondrial	0	0	3	3
Hepatocyte growth factor receptor	0	2	3	5
Tyrosine-protein kinase HCK	0	2	3	5
Proto-oncogene tyrosine-protein kinase ROS	0	0	3	3
Platelet-derived growth factor receptor beta	0	5	3	8
Tyrosine-protein kinase Fgr	0	0	3	3
Wee1-like protein kinase 2	0	0	3	3
Uncharacterized serine/threonine-protein kinase SBK3	0	0	3	3
Serine/threonine-protein kinase A-Raf	0	1	3	4
Glycogen phosphorylase, brain form	0	0	3	3
Myosin light chain kinase, smooth muscle	0	0	3	3
Cyclin-dependent kinase 4	0	1	3	4
ADP/ATP translocase 3	0	0	3	3
Inosine-5'-monophosphate dehydrogenase 2	0	0	3	3
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	3	3
Insulin receptor-related protein	0	0	3	3
Serine/threonine-protein kinase B-raf	0	3	4	7
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	3	3
Tyrosine-protein kinase Fer	0	0	3	3
Protein kinase C alpha type	0	1	3	4
cAMP-dependent protein kinase catalytic subunit alpha	0	0	3	3
Vascular endothelial growth factor receptor 1	0	4	3	7
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	3	3
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	3	3
Casein kinase II subunit alpha'	0	0	3	3
Serine/threonine-protein kinase MAK	0	0	3	3
Cyclin-dependent kinase 11B	0	0	3	3
Ephrin type-A receptor 1	0	0	3	3
Fibroblast growth factor receptor 2	0	1	3	4
Receptor tyrosine-protein kinase erbB-3	0	0	3	3
Multifunctional protein ADE2	0	0	3	3
Fibroblast growth factor receptor 4	0	0	3	3
Fibroblast growth factor receptor 3	0	0	3	3
cAMP-dependent protein kinase catalytic subunit gamma	0	0	3	3
cAMP-dependent protein kinase catalytic subunit beta	0	0	3	3
Ferrochelatase, mitochondrial	0	0	3	3
Ribosomal protein S6 kinase beta-1	0	0	3	3
Tyrosine-protein kinase JAK1	0	0	3	3
Protein kinase C eta type	0	1	3	4
Beta-adrenergic receptor kinase 1	0	0	3	3
Probable ATP-dependent RNA helicase DDX6	0	0	3	3
Activin receptor type-2A	0	0	3	3
Mitogen-activated protein kinase 3	0	1	3	4
MAP/microtubule affinity-regulating kinase 3	0	0	3	3
Deoxycytidine kinase	0	0	3	3
Mitogen-activated protein kinase 1	0	1	3	4
Ephrin type-A receptor 2	0	0	3	3
Ephrin type-A receptor 3	0	0	3	3
Ephrin type-A receptor 8	0	0	3	3
Ephrin type-B receptor 2	0	0	3	3
Leukocyte tyrosine kinase receptor	0	0	3	3
Non-receptor tyrosine-protein kinase TYK2	0	0	3	3
Phosphatidylethanolamine-binding protein 1	0	0	2	2
Wee1-like protein kinase	0	0	3	3
Heme oxygenase 2	0	0	3	3
Tyrosine-protein kinase receptor UFO	0	1	3	4
Mitogen-activated protein kinase 4	0	0	3	3
S-adenosylmethionine synthase isoform type-2	0	0	3	3
DnaJ homolog subfamily A member 1	0	0	3	3
RAC-beta serine/threonine-protein kinase	0	0	3	3
G protein-coupled receptor kinase 4	0	0	3	3
Dual specificity protein kinase TTK	0	0	3	3
DNA replication licensing factor MCM4	0	0	3	3
Tyrosine-protein kinase receptor Tie-1	0	0	3	3
Vascular endothelial growth factor receptor 3	0	4	3	7
Vascular endothelial growth factor receptor 2	0	6	4	11
Dual specificity mitogen-activated protein kinase kinase 2	0	0	3	3
Receptor-type tyrosine-protein kinase FLT3	0	3	3	7
Bone morphogenetic protein receptor type-1A	0	0	3	3
Activin receptor type-1B	0	0	3	3
TGF-beta receptor type-1	0	0	3	3
Serine/threonine-protein kinase receptor R3	0	0	3	3
TGF-beta receptor type-2	0	0	3	3
Tyrosine-protein kinase CSK	0	0	3	3
Glycine--tRNA ligase	0	0	3	3
Protein kinase C iota type	0	1	3	4
Exosome RNA helicase MTR4	0	0	3	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	2	3	5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	2	3	5
Serine/threonine-protein kinase mTOR	0	2	3	5
Megakaryocyte-associated tyrosine-protein kinase	0	0	3	3
Tyrosine-protein kinase Tec	0	0	3	3
Tyrosine-protein kinase TXK	0	0	3	3
Tyrosine-protein kinase ABL2	0	0	3	3
Tyrosine-protein kinase FRK	0	0	3	3
G protein-coupled receptor kinase 6	0	0	3	3
Tyrosine-protein kinase ZAP-70	0	0	3	3
Tyrosine-protein kinase SYK	0	0	3	3
Mitogen-activated protein kinase 8	0	0	3	3
Mitogen-activated protein kinase 9	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 4	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 3	0	0	3	3
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	3	3
Casein kinase I isoform alpha	0	2	3	5
Casein kinase I isoform delta	0	0	3	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	3	5
MAP kinase-activated protein kinase 2	0	0	3	3
Cyclin-dependent kinase 8	0	1	3	4
Elongation factor Tu, mitochondrial	0	0	3	3
Cysteine--tRNA ligase, cytoplasmic	0	0	3	3
Casein kinase I isoform epsilon	0	0	3	3
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	3	3
Dual specificity protein kinase CLK1	0	0	3	3
Dual specificity protein kinase CLK2	0	0	3	3
Dual specificity protein kinase CLK3	0	0	3	3
Glycogen synthase kinase-3 alpha	0	0	3	3
Glycogen synthase kinase-3 beta	0	1	3	4
Cyclin-dependent kinase 7	0	0	3	3
Cyclin-dependent kinase 9	0	0	3	3
Ras-related protein Rab-27A	0	0	3	3
Tyrosine-protein kinase Blk	0	0	3	3
Interleukin-1 receptor-associated kinase 1	0	0	3	3
Ribosomal protein S6 kinase alpha-3	0	1	3	4
Cytoplasmic tyrosine-protein kinase BMX	0	0	3	3
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	3	3
Serine/threonine-protein kinase Nek2	0	1	3	4
Serine/threonine-protein kinase Nek3	0	0	3	3
Serine/threonine-protein kinase Nek4	0	0	3	3
Tyrosine-protein kinase JAK3	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 6	0	0	3	3
Serine/threonine-protein kinase PLK1	0	3	3	6
Death-associated protein kinase 1	0	0	3	3
LIM domain kinase 1	0	0	3	3
LIM domain kinase 2	0	0	3	3
Mitogen-activated protein kinase 12	0	0	3	3
Mitogen-activated protein kinase 10	0	0	3	3
Tyrosine--tRNA ligase, cytoplasmic	0	0	3	3
Ephrin type-B receptor 3	0	0	3	3
Ephrin type-A receptor 5	0	0	3	3
Ephrin type-B receptor 4	0	2	3	5
Ephrin type-B receptor 1	0	0	3	3
Ephrin type-A receptor 4	0	0	3	3
Adenosine kinase	0	0	3	3
Hormonally up-regulated neu tumor-associated kinase	0	0	3	3
Serine/threonine-protein kinase SIK1	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 4	0	0	3	3
Ras-related protein Rab-10	0	0	3	3
Cell division control protein 2 homolog	0	0	3	3
Actin-related protein 3	0	0	3	3
Actin-related protein 2	0	0	3	3
Calcium-dependent protein kinase 1	0	0	3	3
GTP-binding nuclear protein Ran	0	0	3	3
Tubulin alpha-1A chain	0	0	3	3
Casein kinase II subunit alpha	0	0	3	3
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	3	3
SRSF protein kinase 2	0	0	3	3
Casein kinase I isoform gamma-2	0	0	3	3
Mitogen-activated protein kinase kinase kinase 9	0	0	3	3
Serine/threonine-protein kinase PknB	0	0	3	3
Cyclin-dependent kinase 3	0	0	3	3
Cyclin-dependent kinase-like 1	0	0	3	3
Cyclin-dependent kinase 6	0	1	3	4
Cyclin-dependent-like kinase 5	0	0	3	3
Cyclin-dependent kinase 16	0	0	3	3
Cyclin-dependent kinase 17	0	0	3	3
ATP-dependent 6-phosphofructokinase, platelet type	0	0	3	3
Protein kinase C epsilon type	0	1	3	4
Dual specificity mitogen-activated protein kinase kinase 1	0	1	3	4
Angiopoietin-1 receptor	0	2	3	5
Mitogen-activated protein kinase kinase kinase 10	0	0	3	3
DNA topoisomerase 2-beta	0	0	3	3
Protein kinase C theta type	0	1	3	4
Activin receptor type-1	0	0	3	3
Macrophage-stimulating protein receptor	0	0	3	3
Focal adhesion kinase 1	0	1	3	4
Protein kinase C delta type	0	1	3	4
Tyrosine-protein kinase BTK	0	0	3	3
Tyrosine-protein kinase receptor TYRO3	0	0	3	3
Cyclin-dependent kinase 18	0	0	3	3
Activated CDC42 kinase 1	0	0	3	3
Epithelial discoidin domain-containing receptor 1	0	0	3	3
Tyrosine-protein kinase ITK/TSK	0	0	3	3
Myotonin-protein kinase	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	3	3
Mitogen-activated protein kinase kinase kinase 12	0	0	3	3
Serine/threonine-protein kinase 4	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 5	0	0	3	3
Mitogen-activated protein kinase 7	0	0	3	3
Serine/threonine-protein kinase PAK 2	0	0	3	3
Serine/threonine-protein kinase 3	0	0	3	3
Mitogen-activated protein kinase kinase kinase 1	0	0	3	3
cGMP-dependent protein kinase 2	0	0	3	3
Integrin-linked protein kinase	0	0	3	3
Rho-associated protein kinase 1	0	0	3	3
Non-receptor tyrosine-protein kinase TNK1	0	0	3	3
Serine/threonine-protein kinase PRP4 homolog	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 1	0	2	3	5
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	3	3
Activin receptor type-2B	0	0	3	3
Bone morphogenetic protein receptor type-2	0	0	3	3
Protein-tyrosine kinase 6	0	0	3	3
cGMP-dependent protein kinase 1	0	0	3	3
Cyclin-dependent kinase 13	0	0	3	3
Calcium/calmodulin-dependent protein kinase type 1	0	0	3	3
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	3	3
Protein-tyrosine kinase 2-beta	0	0	3	3
Maternal embryonic leucine zipper kinase	0	0	3	3
Structural maintenance of chromosomes protein 1A	0	0	3	3
Chromodomain-helicase-DNA-binding protein 4	0	0	3	3
Peroxisomal acyl-coenzyme A oxidase 1	0	0	3	3
Serine/threonine-protein kinase D1	0	1	3	4
Serine/threonine-protein kinase 38	0	0	3	3
Receptor tyrosine-protein kinase erbB-4	0	0	3	3
Ribosomal protein S6 kinase alpha-2	0	0	3	3
Ephrin type-A receptor 7	0	0	3	3
Delta(24)-sterol reductase	0	0	3	3
Ribosomal protein S6 kinase alpha-1	0	1	3	4
Dual specificity testis-specific protein kinase 1	0	0	3	3
Myosin light chain kinase, smooth muscle	0	0	3	3
Mitogen-activated protein kinase 11	0	0	3	3
Serine/threonine-protein kinase STK11	0	0	3	3
Rhodopsin kinase GRK1	0	0	3	3
NT-3 growth factor receptor	0	0	3	3
Serine/threonine-protein kinase N1	0	0	3	3
Serine/threonine-protein kinase N2	0	0	3	3
Mitogen-activated protein kinase 14	0	1	3	4
Calcium/calmodulin-dependent protein kinase type IV	0	0	3	3
Mitogen-activated protein kinase kinase kinase 11	0	0	3	3
BDNF/NT-3 growth factors receptor	0	0	3	3
Mitogen-activated protein kinase 6	0	0	3	3
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	3	3
Discoidin domain-containing receptor 2	0	2	3	5
AP2-associated protein kinase 1	0	1	3	4
Myosin light chain kinase 3	0	0	3	3
Receptor protein-tyrosine kinase	0	1	0	1
Serine/threonine-protein kinase SBK1	0	0	3	3
Mitogen-activated protein kinase kinase kinase 19	0	0	3	3
Putative heat shock protein HSP 90-beta 2	0	0	3	3
Serine/threonine-protein kinase TNNI3K	0	1	3	4
Rab-like protein 3	0	0	3	3
Leucine-rich repeat serine/threonine-protein kinase 2	0	1	3	4
Serine/threonine-protein kinase MRCK alpha	0	0	3	3
Serine/threonine-protein kinase MRCK gamma	0	0	3	3
Acyl-CoA dehydrogenase family member 10	0	0	2	2
Serine/threonine-protein kinase Nek5	0	0	3	3
Serine/threonine-protein kinase N3	0	0	3	3
Serine/threonine-protein kinase ULK3	0	0	3	3
Dual serine/threonine and tyrosine protein kinase	0	0	3	3
Mitogen-activated protein kinase kinase kinase 15	0	0	3	3
Uncharacterized protein FLJ45252	0	0	3	3
Acyl-CoA dehydrogenase family member 11	0	0	3	3
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	2	2
Serine/threonine-protein kinase MARK2	0	0	3	3
ATP-dependent RNA helicase DHX30	0	0	3	3
Serine/threonine-protein kinase TAO1	0	0	3	3
STE20-related kinase adapter protein alpha	0	0	3	3
Myosin-14	0	0	3	3
AarF domain-containing protein kinase 1	0	0	3	3
Serine/threonine-protein kinase tousled-like 2	0	0	3	3
Serine/threonine-protein kinase 32C	0	0	3	3
Serine/threonine-protein kinase pim-3	0	0	3	3
ATP-dependent RNA helicase DDX42	0	0	2	2
Serine/threonine-protein kinase VRK2	0	0	3	3
Myosin light chain kinase family member 4	0	0	3	3
Homeodomain-interacting protein kinase 1	0	1	3	4
Calcium/calmodulin-dependent protein kinase type 1D	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	3	3
Cyclin-dependent kinase-like 3	0	0	3	3
MAP kinase-activated protein kinase 5	0	0	3	3
Serine/threonine-protein kinase BRSK2	0	0	3	3
Serine/threonine-protein kinase NIM1	0	0	3	3
Serine/threonine-protein kinase ULK2	0	0	3	3
Misshapen-like kinase 1	0	0	3	3
Serine/threonine-protein kinase DCLK2	0	0	3	3
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	3	3
Casein kinase I isoform alpha-like	0	0	3	3
Homeodomain-interacting protein kinase 4	0	1	3	4
Myosin-IIIa	0	0	3	3
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	3	3
Serine/threonine-protein kinase Nek11	0	0	3	3
Atypical kinase COQ8A, mitochondrial	0	0	3	3
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	3	3
Mitogen-activated protein kinase 15	0	0	3	3
Serine/threonine-protein kinase Nek9	0	0	3	3
Serine/threonine-protein kinase BRSK1	0	0	3	3
Serine/threonine-protein kinase 35	0	0	3	3
Serine/threonine-protein kinase Nek7	0	0	3	3
Rhodopsin kinase GRK7	0	0	3	3
Serine/threonine-protein kinase 32A	0	0	3	3
Myosin-IIIb	0	0	3	3
ATP-dependent RNA helicase DDX1	0	0	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	3	3
Cyclin-dependent kinase-like 2	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	3	3
Serine/threonine-protein kinase Sgk3	0	0	3	3
Atypical kinase COQ8B, mitochondrial	0	0	3	3
Aurora kinase B	0	1	3	4
MAP/microtubule affinity-regulating kinase 4	0	0	3	3
Calcium/calmodulin-dependent protein kinase type 1G	0	0	3	3
Serine/threonine-protein kinase Nek1	0	0	3	3
Cyclin-dependent kinase 15	0	0	3	3
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	3	3
EKC/KEOPS complex subunit TP53RK	0	0	3	3
SRSF protein kinase 1	0	0	3	3
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	3	3
Mitogen-activated protein kinase kinase kinase 5	0	0	3	3
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	3	3
Mitogen-activated protein kinase kinase kinase 3	0	0	3	3
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	3	3
Serine/threonine-protein kinase RIO1	0	0	3	3
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	3	3
Serine/threonine-protein kinase RIO2	0	0	3	3
Cyclin-dependent kinase 19	0	1	3	4
Transient receptor potential cation channel subfamily M member 6	0	0	3	3
Testis-specific serine/threonine-protein kinase 1	0	0	3	3
Serine/threonine-protein kinase 33	0	0	3	3
Nucleolar GTP-binding protein 1	0	0	3	3
Serine/threonine-protein kinase D2	0	0	3	3
Serine/threonine-protein kinase DCLK3	0	0	3	3
NUAK family SNF1-like kinase 2	0	0	3	3
RNA cytidine acetyltransferase	0	0	3	3
Serine/threonine-protein kinase SIK2	0	0	3	3
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	3	3
STE20-like serine/threonine-protein kinase	0	0	3	3
Serine/threonine-protein kinase TAO3	0	0	3	3
Homeodomain-interacting protein kinase 2	0	1	3	4
Tyrosine-protein kinase Srms	0	0	3	3
Homeodomain-interacting protein kinase 3	0	1	3	4
Serine/threonine-protein kinase PLK3	0	2	3	5
dCTP pyrophosphatase 1	0	0	3	3
Dual specificity protein kinase CLK4	0	0	3	3
MAP kinase-interacting serine/threonine-protein kinase 2	0	1	3	4
Serine/threonine-protein kinase Nek6	0	0	3	3
Casein kinase I isoform gamma-1	0	0	3	3
Serine/threonine-protein kinase PAK 6	0	1	3	4
SNF-related serine/threonine-protein kinase	0	0	3	3
Serine/threonine-protein kinase LATS2	0	0	3	3
Serine/threonine-protein kinase 36	0	0	3	3
Phenylalanine--tRNA ligase beta subunit	0	0	3	3
Isoleucine--tRNA ligase, mitochondrial	0	0	3	3
BMP-2-inducible protein kinase	0	0	3	3
Obg-like ATPase 1	0	0	3	3
Midasin	0	0	3	3
Interleukin-1 receptor-associated kinase 4	0	0	3	3
Serine/threonine-protein kinase 32B	0	0	3	3
Mitogen-activated protein kinase kinase kinase 20	0	0	3	3
Cyclin-dependent kinase 12	0	0	3	3
Serine/threonine-protein kinase PLK2	0	2	3	5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	3	3
Serine/threonine-protein kinase MARK1	0	0	3	3
Serine/threonine-protein kinase pim-2	0	0	3	3
Serine/threonine-protein kinase PAK 5	0	1	3	4
Serine/threonine-protein kinase 26	0	0	3	3
eIF-2-alpha kinase GCN2	0	0	3	3
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	3	3
Serine/threonine-protein kinase NLK	0	0	3	3
Serine/threonine-protein kinase 17A	0	0	3	3
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	3	3
Ephrin type-A receptor 6	0	0	3	3
Serine/threonine-protein kinase TBK1	0	1	3	4
Septin-9	0	0	3	3
Death-associated protein kinase 2	0	0	3	3
Ribosomal protein S6 kinase alpha-6	0	0	3	3
TRAF2 and NCK-interacting protein kinase	0	0	3	3
Serine/threonine-protein kinase tousled-like 1	0	0	3	3
Serine/threonine-protein kinase TAO2	0	0	3	3
Long-chain-fatty-acid--CoA ligase 5	0	0	3	3
ALK tyrosine kinase receptor	0	1	3	4
SRSF protein kinase 3	0	0	3	3
Serine/threonine-protein kinase ICK	0	0	3	3
Cyclin-dependent kinase 11A	0	0	3	3
Aurora kinase C	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	3	3
RAC-gamma serine/threonine-protein kinase	0	0	3	3
Serine/threonine-protein kinase 38-like	0	0	3	3
Microtubule-associated serine/threonine-protein kinase 1	0	0	3	3
Serine/threonine-protein kinase SIK3	0	0	3	3
Mitogen-activated protein kinase kinase kinase 2	0	0	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 3	0	1	3	4
Serine/threonine-protein kinase MRCK beta	0	0	3	3
Interleukin-1 receptor-associated kinase 3	0	0	3	3
Serine/threonine-protein kinase 24	0	0	3	3
Casein kinase I isoform gamma-3	0	0	3	3
Mitogen-activated protein kinase kinase kinase 4	0	0	3	3
Growth factor receptor-bound protein 2	0	0	0	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Cytochrome P450 2A13	0	1	1	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase OXA-7	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Metallo-beta-lactamase VIM-13	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Beta-lactamase VIM-1	0	0	0	1
luciferase	0	0	0	1
Estrogen receptor	0	4	1	6
Progesterone receptor	0	3	0	4
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	4	1	5
Solute carrier family 22 member 8	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	2	0	2
Canalicular multispecific organic anion transporter 1	0	1	0	1
Pannexin-1	0	1	0	1
Solute carrier family 22 member 12	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Solute carrier family 22 member 8	0	2	0	2
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Sodium-dependent noradrenaline transporter	0	4	0	4
5-hydroxytryptamine receptor 2B	0	5	0	5
UDP-glucuronosyltransferase 1A8	0	0	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
Solute carrier organic anion transporter family member 1A2	0	1	0	2
DNA-directed RNA polymerase subunit beta	0	1	0	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
melanocortin receptor 4	0	1	1	2
Cell division cycle 7-related protein kinase	0	0	2	2
Tyrosine-protein kinase ABL1	0	1	0	1
Platelet-derived growth factor receptor beta	0	2	0	2
Adenine phosphoribosyltransferase	0	0	2	2
Ras-related protein Rab-6A	0	0	2	2
G1/S-specific cyclin-D1	0	1	0	1
Cyclin-C	0	1	1	2
Serine/threonine-protein kinase B-raf	0	1	0	1
5-hydroxytryptamine receptor 2A	0	3	0	3
5-hydroxytryptamine receptor 7	0	1	0	1
Myosin-10	0	0	2	2
Vascular endothelial growth factor receptor 3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Electron transfer flavoprotein subunit beta	0	0	2	2
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 6	0	3	0	3
DNA-dependent protein kinase catalytic subunit	0	2	0	2
Protein delta homolog 1	0	1	2	3
Protein kinase C zeta type	0	1	2	3
Serine/threonine-protein kinase ATR	0	0	2	2
MAP kinase-activated protein kinase 3	0	0	1	1
Vascular endothelial growth factor receptor 2	0	1	0	1
PAS domain-containing serine/threonine-protein kinase	0	0	2	2
Dual specificity testis-specific protein kinase 2	0	0	1	1
Poly [ADP-ribose] polymerase tankyrase-2	0	0	2	2
RuvB-like 2	0	1	1	2
RuvB-like 1	0	1	0	1
Thyroid hormone receptor-associated protein 3	0	0	2	2
Eukaryotic translation initiation factor 5B	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Mast/stem cell growth factor receptor Kit	0	1	0	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	0	1
Platelet-derived growth factor receptor alpha	0	1	0	1
UMP-CMP kinase	0	0	1	1
G protein-coupled receptor kinase 5	0	1	0	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Cyclin-dependent kinase 10	0	0	1	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
Bromodomain-containing protein 9	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Bromodomain-containing protein 7	0	0	1	1
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-P receptor	0	4	1	5
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
isocitrate dehydrogenase 1, partial	1	0	0	1
nonstructural protein 1	0	1	0	1
protein AF-9 isoform a	0	0	0	1
Vpr	1	0	0	1
Chain A, CES1 protein	0	1	0	1
DNA polymerase III, partial	1	0	0	1
interferon gamma precursor	0	0	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Estrogen receptor	0	0	1	2
Beta-1 adrenergic receptor	0	4	0	4
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Adenosine receptor A3	0	2	0	2
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Angiotensin-converting enzyme	0	2	0	2
Beta-3 adrenergic receptor	0	4	0	4
D(2) dopamine receptor	0	2	0	2
D(1A) dopamine receptor	0	2	0	2
D(4) dopamine receptor	0	2	0	2
Histamine H2 receptor	0	2	0	2
Adenosine receptor A2a	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
D(3) dopamine receptor	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Estrogen receptor beta	0	0	1	2
Protein kinase C eta type	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Beta-2 adrenergic receptor	0	2	0	2
Beta-1 adrenergic receptor	0	1	0	1
Beta-2 adrenergic receptor	0	0	1	1
Protein Rev	0	0	1	1
Microtubule-associated protein tau	0	2	0	2
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Stromelysin-1	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Phospholipase A-2-activating protein	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Guanine deaminase	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Transporter	0	1	0	1
Albumin	0	0	1	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(5)

Research Excerpts

Overview

Context

Treatment

Research

Studies (1,146)

Protein Targets (1,847)

Macular Holes

Synonyms(5)

Research Excerpts

Overview

Context

Treatment

Research

Studies (1,146)

Drugs Studied (203)

Protein Targets (1,847)