perfluorophenanthrene profile

perfluorophenanthrene: mixture of isomers of perfluorophenanthrene; MF: C14-F24 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	78972
CHEMBL ID	3188494
CHEBI ID	39423
SCHEMBL ID	145943
MeSH ID	M0137697

Synonym
phenanthrene, tetracosafluorotetradecahydro-
zz3t53gwv9 ,
phenanthrene, 1,1,2,2,3,3,4,4,4a,4b,5,5,6,6,7,7,8,8,8a,9,9,10,10,10a-tetracosafluorotetradecahydro-
unii-zz3t53gwv9
perfluoroperhydrophenanthrene
perfluorophenanthrene
CHEBI:39423 ,
tetracosafluorotetradecahydrophenanthrene
306-91-2
phenanthrene,tetracosafluorotetradecahydro-
flutec pp11
1,1,2,2,3,3,4,4,4a,4b,5,5,6,6,7,7,8,8,8a,9,9,10,10,10a-tetracosafluorophenanthrene
cas-306-91-2
dtxsid1047029 ,
NCGC00256219-01
tox21_302291
dtxcid9027029
FT-0676095
perfluoro(perhydrophenanthrene)
AKOS015853419
fiflow 220
flutec pc-11
fiflow 180
perfluorinated tetradecahydrophenanthrene
perfluorotetradecahydrophenanthrene
perfluoroperhydrophenanthrene [inci]
flutec pp 11
SCHEMBL145943
fc 5311
CHEMBL3188494
mfcd00042596
flutec pp11 for electronic applications
perfluoroperhydrophenanthrene, selectophore(tm)
J-018059
CS-0207499
Q27119859

Role	Description
radioopaque medium	A substance having the property of absorbing, and therefore being opaque to, electromagnetic radiation, particularly X-rays.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class	Description
fluorocarbon	Compounds consisting wholly of fluorine and carbon.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
GLI family zinc finger 3	Homo sapiens (human)	Potency	22.3040	0.0007	14.5928	83.7951	AID1259369
estrogen nuclear receptor alpha	Homo sapiens (human)	Potency	49.9323	0.0002	29.3054	16,493.5996	AID743079
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	1 (2.50)	18.7374
1990's	32 (80.00)	18.2507
2000's	4 (10.00)	29.6817
2010's	1 (2.50)	24.3611
2020's	2 (5.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	9 (17.65%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	12 (23.53%)	4.05%
Observational	0 (0.00%)	0.25%
Other	30 (58.82%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
naphthacene tetracene : An acene that consists of four ortho-fused benzene rings in a rectilinear arrangement.	2.05	1	0	acene; tetracenes
anthracene acene : A polycyclic aromatic hydrocarbon consisting of fused benzene rings in a rectilinear arrangement.. acenes : Polycyclic aromatic hydrocarbons consisting of fused benzene rings in a rectilinear arrangement and their substitution derivatives.	2.05	1	0	acene; anthracenes; ortho-fused tricyclic hydrocarbon
triphenylene triphenylene: structure. triphenylene : An ortho-fused polycyclic arene consisting of four fused benzene rings.	2.05	1	0	ortho-fused polycyclic arene
chrysene chrysene: structure in Merck Index, 9th ed, #2252. chrysene : An ortho-fused polycyclic arene found commonly in the coal tar.	2.05	1	0	ortho-fused polycyclic arene	plant metabolite
perfluorodecalin perfluorodecalin: RN given refers to parent cpd without isomeric designation. perfluorodecalin : A fluorocarbon that is decalin in which every hydrogen is replaced by fluorine. Capable of dissolving large quantities of oxygen, it has been used as the basis of an artificial blood substitute.	2.39	2	0	fluorocarbon	blood substitute; solvent
perfluorooctane perfluorooctane: used in the treatment of giant retinal tears with proliferative vitreoretinopathy	4.86	4	2	fluoroalkane; fluorocarbon
fluorescein Fluorescein: A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium such as the aqueous humor.. fluorescein (lactone form) : A xanthene dye that is highly fluorescent, detectable even when present in minute quantities. Used forensically to detect traces of blood, in analytical chemistry as an indicator in silver nitrate titrations and in microscopy.	2.31	1	0	2-benzofurans; gamma-lactone; organic heteropentacyclic compound; oxaspiro compound; polyphenol; xanthene dye	fluorescent dye; radioopaque medium
silver Silver: An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.	2.05	1	0	copper group element atom; elemental silver	Escherichia coli metabolite
fluorine Fluorine: A nonmetallic, diatomic gas that is a trace element and member of the halogen family. It is used in dentistry as fluoride (FLUORIDES) to prevent dental caries.	2.05	1	0	diatomic fluorine; gas molecular entity	NMR chemical shift reference compound
pyrene pyrene: structure in Merck Index, 9th ed, #7746. pyrene : An ortho- and peri-fused polycyclic arene consisting of four fused benzene rings, resulting in a flat aromatic system.	2.05	1	0	ortho- and peri-fused polycyclic arene	fluorescent probe; persistent organic pollutant
rhodamine 123 Rhodamine 123: A fluorescent probe with low toxicity which is a potent substrate for ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B, MEMBER 1 and the bacterial multidrug efflux transporter. It is used to assess mitochondrial bioenergetics in living cells and to measure the efflux activity of ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B, MEMBER 1 in both normal and malignant cells. (Leukemia 1997;11(7):1124-30). rhodamine 123(1+) : A cationic fluorescent dye derived from 9-phenylxanthene.	2.31	1	0	organic cation; xanthene dye	fluorochrome
colistin Colistin: Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.. colistin : A multi-component mixture comprising mostly of colistin A (R = Me) and B (R = H), with small amounts of colistin C and other polymyxins, produced by certain strains of Bacillus polymyxa var. colistinus. An antibiotic, it is used as its sulfate salt (for oral or topical use) or as the sodium salt of the N-methylsulfonic acid derivative (the injectable form) in the treatment of severe Gram-negative infections, partiularly those due to Pseudomonas aeruginosa.	2.31	1	0

Condition	Relationship Strength	Studies	Trials
Retinal Pigment Epithelial Detachment [description not available]	6.07	16	2
Retrolental Fibroplasia [description not available]	1.98	1	0
Retinal Detachment Separation of the inner layers of the retina (neural retina) from the pigment epithelium. Retinal detachment occurs more commonly in men than in women, in eyes with degenerative myopia, in aging and in aphakia. It may occur after an uncomplicated cataract extraction, but it is seen more often if vitreous humor has been lost during surgery. (Dorland, 27th ed; Newell, Ophthalmology: Principles and Concepts, 7th ed, p310-12).	6.07	16	2
Retinopathy of Prematurity A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)	1.98	1	0
Eye Disorders [description not available]	5.67	7	3
Complication, Postoperative [description not available]	4.98	9	1
Day Blindness [description not available]	2.38	2	0
Eye Diseases Diseases affecting the eye.	5.67	7	3
Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.	4.98	9	1
Lens Dislocation [description not available]	2.89	4	0
Glaucoma, Suspect [description not available]	1.98	1	0
Glaucoma An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)	6.98	1	0
Intraocular Pressure The pressure of the fluids in the eye.	4.63	6	1
Ocular Hypertension A condition in which the intraocular pressure is elevated above normal and which may lead to glaucoma.	1.98	1	0
Complication, Intraoperative [description not available]	3.78	2	1
Retinal Diseases Diseases involving the RETINA.	5.79	8	3
Hemorrhage, Vitreous [description not available]	2.38	2	0
Wounds, Gunshot Disruption of structural continuity of the body as a result of the discharge of firearms.	1.98	1	0
Eye Injuries, Penetrating Deeply perforating or puncturing type intraocular injuries.	2.68	3	0
Vitreous Hemorrhage Hemorrhage into the VITREOUS BODY.	2.38	2	0
Recrudescence [description not available]	3.77	2	1
Macular Holes [description not available]	4.84	4	2
Retinal Perforations Perforations through the whole thickness of the retina including the macula as the result of inflammation, trauma, degeneration, etc. The concept includes retinal breaks, tears, dialyses, and holes.	4.84	4	2
Choroid Diseases Disorders of the choroid including hereditary choroidal diseases, neoplasms, and other abnormalities of the vascular layer of the uvea.	1.98	1	0
Choroid Hemorrhage Hemorrhage from the vessels of the choroid.	2.38	2	0
Injuries, Eye [description not available]	1.98	1	0
Eye Injuries Damage or trauma inflicted to the eye by external means. The concept includes both surface injuries and intraocular injuries.	1.98	1	0
Proliferative Vitreoretinopathy [description not available]	3.79	2	1
Vitreoretinopathy, Proliferative Vitreoretinal membrane shrinkage or contraction secondary to the proliferation of primarily retinal pigment epithelial cells and glial cells, particularly fibrous astrocytes, followed by membrane formation. The formation of fibrillar collagen and cellular proliferation appear to be the basis for the contractile properties of the epiretinal and vitreous membranes.	3.79	2	1
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.	2.4	2	0
Corneal Edema An excessive amount of fluid in the cornea due to damage of the epithelium or endothelium causing decreased visual acuity.	2.69	3	0
Innate Inflammatory Response [description not available]	2	1	0
Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.	2	1	0
Coloboma Congenital anomaly in which some of the structures of the eye are absent due to incomplete fusion of the fetal intraocular fissure during gestation.	1.98	1	0

perfluorophenanthrene

Description

Cross-References

Synonyms (36)

Research Excerpts

Roles (1)

Drug Classes (1)

Protein Targets (2)

Potency Measurements

Research

Studies (40)

Market Indicators

Research Demand Index: 12.24

Study Types

perfluorophenanthrene

Description

Cross-References

Synonyms (36)

Research Excerpts

Roles (1)

Drug Classes (1)

Protein Targets (2)

Potency Measurements

Research

Studies (40)

Market Indicators

Research Demand Index: 12.24

Study Types

Related Drugs (12)

Related Conditions (34)