light green sf profile

Light green SF: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

acid green 5 : An organic sodium salt having 3-[(ethyl{4-[(4-{ethyl[(3-sulfonatophenyl)methyl]amino}phenyl)(4-sulfonatophenyl)methylidene]cyclohexa-2,5-dien-1-ylidene}azaniumyl)methyl]benzene-1-sulfonate as the counterion. It is the standard dye in North American for staining collagen and is also used extensively in plant histology. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID Source	ID
PubMed CID	21223
CHEBI ID	87065
SCHEMBL ID	333260
MeSH ID	M0066615

Synonyms (107)

Synonym
disodium 3-[(ethyl{(1z,4z)-4-[(4-{ethyl[(3-sulfonatophenyl)methyl]amino}phenyl)(4-sulfonatophenyl)methylidene]cyclohexa-2,5-dien-1-ylidene}ammonio)methyl]benzenesulfonate
fd & c green no. 2
nsc 9619
fd&c green no. 2
zelen svetla sf [czech]
benzenemethanaminium, n-ethyl-n-(4-((4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)(4-sulfophenyl)methylene)-2,5-cyclohexadien-1-ylidene)-3-sulfo-, inner salt, disodium salt
fd and c green no. 4
ccris 889
ammonium, ethyl(4-(p-(ethyl(m-sulfobenzyl)amino)-alpha-(p-sulfophenyl)benzylidene)-2,5-cyclohexadien-1-ylidene)(m-sulfobenzyl)-, hydroxide, inner salt, disodium salt
lichtgruen [german]
benzenemethanaminium, n-ethyl-n-(4-((4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)(4-sulfophenyl)methylene)-2,5-cyclohexadien-1-ylidene)-3-sulfo-, hydroxide, inner salt, disodium salt
benzenemethanaminium, n-ethyl-n-(4-((4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)(4-sulfophenyl)methy lene)-2,5-cyclohexadien-1-ylidene)-3-sulfo-, hydroxide, inner salt, disodium salt
fd&c green no. 2 - aluminum lake
zelen kysela f [czech]
c.i. 670
einecs 225-906-5
light green fcf yellowish
zelen kysela 5 [czech]
zelen potravinarska 2 [czech]
dihydrogen (ethyl)(4-(p-(ethyl(m-sulphonatobenzyl)amino)-p'-sulphonatobenzhydrylene)cyclohexa-2,5-dien-1-ylidene)(m-sulphonatobenzyl)ammonium, disodium salt
d&c green no. 2
my/68
lissamine green sf
sulfo green j
light green 2gn
light green lake
c.i. food green 2
light green sfa
leather green sf
light sf yellowish (biological stain)
light green g
acid green 5
lissamine lake green sf
light green sfd
fast acid green n
c.i. acid green 5
acilan green sfg
light green s
lichtgruen
light green sf
a.f. green no. 2
acidal light green sf
fenazo green 7g
food green 2
a f green no.2
sumitomo light green sf yellowish
pencil green sf
merantine green sf
fd and c green no. 2-aluminum lake
light green fs
d and c green no. 4
amacid green g
acid brilliant green sf
green no. 203
light green yellowish
nsc-9619
light green cf
5141-20-8
light green sf yellowish
c.i. acid green 5, disodium salt
acid green gg
L0054
L0141
guinea green 2g
zelen svetla sf
benzenemethanaminium, n-ethyl-n-(4-((4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)(4-sulfophenyl)methylene)-2,5-cyclohexadien-1-ylidene)-3-sulfo-, inner salt, sodium salt (1:2)
hsdb 8009
3f7bha64z0 ,
unii-3f7bha64z0
zelen kysela 5
zelen kysela f
zelen potravinarska 2
FT-0627852
AKOS015902760
AKOS025310847
light green sf yellowish [mi]
midori205
benzenemethanaminium, n-ethyl-n-((1z,4z)-4-((4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)(4-sulfophenyl)methylene)-2,5-cyclohexadien-1-ylidene)-3-sulfo-, inner salt, disodium salt
green no. 205
midori205 [inci]
benzenemethanaminium, n-ethyl-n-(4-((4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)(4-sulfophenyl)methy lene)- 2,5-cyclohexadien-1-ylidene)-3-sulfo-, hydroxide, inner salt, disodium salt
acid brilliant green 5
fd&c green no. 2 (delisted)
light green sf [iarc]
ci 42095
disodium 3-((ethyl((1z,4z)-4-((4-(ethyl(3-sulphonatobenzyl)amino)phenyl)(4-sulphonatophenyl)methylene)cyclohexa-2,5-dien-1-ylidene)ammonio)methyl)benzenesulphonate
disodium 3-((ethyl((1z,4z)-4-((4-(ethyl(3-sulfonatobenzyl)amino)phenyl)(4-sulfonatophenyl)methylene)cyclohexa-2,5-dien-1-ylidene)ammonio)methyl)benzenesulfonate
SCHEMBL333260
CHEBI:87065 ,
disodium 3-[(ethyl{4-[(4-{ethyl[(3-sulfonatophenyl)methyl]amino}phenyl)(4-sulfonatophenyl)methylidene]cyclohexa-2,5-dien-1-ylidene}azaniumyl)methyl]benzene-1-sulfonate
mfcd00012121
DTXSID8020672 ,
DB11183
sodium 3-(((e)-ethyl((e)-4-((4-(ethyl(3-sulfonatobenzyl)amino)phenyl)(4-sulfonatophenyl)methylene)cyclohexa-2,5-dienylidene)ammonio)methyl)benzenesulfonate
Q6546012
disodium;3-[[n-ethyl-4-[[4-[ethyl-[(3-sulfonatophenyl)methyl]azaniumylidene]cyclohexa-2,5-dien-1-ylidene]-(4-sulfonatophenyl)methyl]anilino]methyl]benzenesulfonate
sodium 3-((ethyl((1e,4e)-4-((4-(ethyl(3-sulfonatobenzyl)amino)phenyl)(4-sulfonatophenyl)methylene)cyclohexa-2,5-dien-1-ylidene)ammonio)methyl)benzenesulfonate
sodium 3-((-ethyl(-4-((4-(ethyl(3-sulfonatobenzyl)amino)phenyl)(4-sulfonatophenyl)methylene)cyclohexa-2,5-dien-1-ylidene)ammonio)methyl)benzenesulfonate
D91235
sodium3-((-ethyl(-4-((4-(ethyl(3-sulfonatobenzyl)amino)phenyl)(4-sulfonatophenyl)methylene)cyclohexa-2,5-dien-1-ylidene)ammonio)methyl)benzenesulfonate
AS-83738
n-ethyl-n-(4-((3-sulfophenyl)methyl)amino)-phenyl)-(4-sulfophenyl)methylene)-2,5-cyclohexadien-1-ylidene)-3-sulfobenzenemethanaminium hydroxide inner salt, disodium salt
light green sf (iarc)
disodium 3-((ethyl(4-((4-(ethyl((3-sulfonatophenyl)methyl)amino)phenyl)(4-sulfonatophenyl)methylidene)cyclohexa-2,5-dien-1-ylidene)azaniumyl)methyl)benzene-1-sulfonate
d&c green no. 4
greenglo
dtxcid60672

Excerpt	Reference	Relevance
" Adverse effects on anterior and posterior segments were evaluated by slit lamp biomicroscopy and ophthalmoscopy."	( Administration of novel dyes for intraocular surgery: an in vivo toxicity animal study. Eibl, K; Freyer, W; Haritoglou, C; Kampik, A; Mankowska, A; May, CA; Rejdak, R; Schuettauf, F; Thaler, S; Zrenner, E, 2006)	0.33
"BPB or LGSF produced no significantly detectable toxic effects on the retina in vivo."	( Administration of novel dyes for intraocular surgery: an in vivo toxicity animal study. Eibl, K; Freyer, W; Haritoglou, C; Kampik, A; Mankowska, A; May, CA; Rejdak, R; Schuettauf, F; Thaler, S; Zrenner, E, 2006)	0.33

Role	Description
histological dye	A dye used in microscopic or electron microscopic examination of cells and tissues to give contrast and to highlight particular features of interest, such as nuclei and cytoplasm.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class	Description
organic sodium salt
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	5 (45.45)	18.7374
1990's	1 (9.09)	18.2507
2000's	2 (18.18)	29.6817
2010's	1 (9.09)	24.3611
2020's	2 (18.18)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (7.69%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	12 (92.31%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
bromphenol blue Bromphenol Blue: A dye that has been used as an industrial dye, a laboratory indicator, and a biological stain.. bromophenol blue : 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 3,5-dibromo-4-hydroxyphenyl groups. It is used as a laboratory indicator, changing from yellow below pH 3 to purple at pH 4.6, and as a size marker for monitoring the progress of agarose gel and polyacrylamide gel electrophoresis. It has also been used as an industrial dye.	2.43	2	2,1-benzoxathiole; arenesulfonate ester; organobromine compound; phenols; sultone	acid-base indicator; dye; two-colour indicator
hematoxylin Hematoxylin: A dye obtained from the heartwood of logwood (Haematoxylon campechianum Linn., Leguminosae) used as a stain in microscopy and in the manufacture of ink.	3.06	1	organic heterotetracyclic compound; oxacycle; polyphenol; tertiary alcohol	histological dye; plant metabolite
triphenylmethane triphenylmethane : A triarylmethane in which the three aryl groups are phenyl. It forms the basic skeleton of several synthetic dyes.	6.93	1	triarylmethane	environmental contaminant; xenobiotic
eosine yellowish-(ys) Eosine Yellowish-(YS): A versatile red dye used in cosmetics, pharmaceuticals, textiles, etc., and as tissue stain, vital stain, and counterstain with HEMATOXYLIN. It is also used in special culture media.. eosin YS dye : An organic sodium salt that is 2',4',5',7'-tetrabromofluorescein in which the carboxy group and the phenolic hydroxy group have been deprotonated and the resulting charge is neutralised by two sodium ions.	3.06	1	organic sodium salt; organobromine compound	fluorochrome; histological dye
rhodamine 6g rhodamine 6G: RN given refers to HCl	2.02	1
orange g orange G : An organic sodium salt that is the disodium salt of 7-hydroxy-8-[(E)-phenyldiazenyl]naphthalene-1,3-disulfonic acid. It is often combined with other yellow dyes in alcoholic solution to stain erythrocytes in trichrome methods, and is used for demonstrating cells in the pancreas and pituitary.	3.06	1
c.i. direct blue 1 [no description available]	2.43	2
sodium azide Sodium Azide: A cytochrome oxidase inhibitor which is a nitridizing agent and an inhibitor of terminal oxidation. (From Merck Index, 12th ed). sodium azide : The sodium salt of hydrogen azide (hydrazoic acid).	2.07	1	inorganic sodium salt	antibacterial agent; explosive; mitochondrial respiratory-chain inhibitor; mutagen
acridine orange Acridine Orange: A cationic cytochemical stain specific for cell nuclei, especially DNA. It is used as a supravital stain and in fluorescence cytochemistry. It may cause mutations in microorganisms.. acridine orange : Fluorescent dye useful for cell cycle determination. It is cell-permeable, and interacts with DNA and RNA by intercalation or electrostatic attractions respectively.. acridine orange free base : A member of the class of aminoacridines that is acridine carrying two dimethylamino substituents at positions 3 and 6. The hydrochloride salt is the fluorescent dye 'acridine orange', used for cell cycle determination.	2.02	1	aminoacridines; aromatic amine; tertiary amino compound	fluorochrome; histological dye
bismark brown Bismark Brown: RN given refers to parent cpd	3.06	1
betadex beta-Cyclodextrins: Cyclic GLUCANS consisting of seven (7) glucopyranose units linked by 1,4-glycosidic bonds.	2.31	1	cyclodextrin
aluminum Aluminum: A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.	3.06	1	boron group element atom; elemental aluminium; metal atom
trypan blue Trypan Blue: A diazo-naphthalene sulfonate that is widely used as a stain.. trypan blue : An organosulfonate salt that is the tetrasodium salt of 3,3'-[(3,3'-dimethylbiphenyl-4,4'-diyl)didiazene-2,1-diyl]bis(5-amino-4-hydroxynaphthalene-2,7-disulfonic acid).	2.43	2

Condition	Relationship Strength	Studies
Sarcoma, Epithelioid [description not available]	1.92	1
EHS Tumor [description not available]	2.33	2
Sarcoma A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.	6.92	1
Epiretinal Membrane A membrane on the vitreal surface of the retina resulting from the proliferation of one or more of three retinal elements: (1) fibrous astrocytes; (2) fibrocytes; and (3) RETINAL PIGMENT EPITHELIUM. Localized epiretinal membranes may occur at the posterior pole of the eye without clinical signs or may cause marked loss of vision as a result of covering, distorting, or detaching the FOVEA CENTRALIS. Epiretinal membranes may cause vascular leakage and secondary retinal edema. In younger individuals some membranes appear to be developmental in origin and occur in otherwise normal eyes. The majority occur in association with RETINAL HOLES, ocular concussions, retinal inflammation, or after ocular surgery. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p291)	2.43	2
Macular Holes [description not available]	2.03	1
Retinal Perforations Perforations through the whole thickness of the retina including the macula as the result of inflammation, trauma, degeneration, etc. The concept includes retinal breaks, tears, dialyses, and holes.	2.03	1

light green sf

Description

Cross-References

Synonyms (107)

Research Excerpts

Toxicity

Roles (1)

Drug Classes (1)

Research

Studies (11)

Market Indicators

Research Demand Index: 36.84

Study Types

light green sf

Description

Cross-References

Synonyms (107)

Research Excerpts

Toxicity

Roles (1)

Drug Classes (1)

Research

Studies (11)

Market Indicators

Research Demand Index: 36.84

Study Types

Related Drugs (13)

Related Conditions (6)