Page last updated: 2024-09-27

Thrombotic Microangiopathies

Diseases that result in THROMBOSIS in MICROVASCULATURE. The two most prominent diseases are PURPURA, THROMBOTIC THROMBOCYTOPENIC; and HEMOLYTIC-UREMIC SYNDROME. Multiple etiological factors include VASCULAR ENDOTHELIAL CELL damage due to SHIGA TOXIN; FACTOR H deficiency; and aberrant VON WILLEBRAND FACTOR formation.

Synonyms(1)

Synonym
Thrombotic Microangiopathies

Research Excerpts

Overview

ExcerptReference
"Thrombotic microangiopathies are a rare group of disorders with features such as microangiopathic haemolytic anaemia, thrombocytopenia and renal failure."( Casamento, AJ; Isbister, GK, 2011)
"Thrombotic microangiopathies are rare diseases associated with significant morbidity and mortality."( Lerfald, N; Regner, SR, 2019)

Research

Studies (309)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's6 (1.94)18.1394
2010's196 (63.43)28.8240
2020's107 (34.63)9.53
DrugIndicatedRelationship StrengthStudiesTrials
citric acid, anhydrous0low20
methylmalonic acid0low30
creatine0low10
cytosine0low10
glycine0low10
niacinamide0low30
pyridoxal phosphate0low10
acetaminophen0low10
ambroxol0low10
amlodipine0low30
azathioprine0low20
busulfan0medium21
candesartan0low10
carvedilol0low10
ciprofloxacin0low20
valproic acid0low10
foscarnet0low10
hydroxychloroquine0low20
ifosfamide0low10
leflunomide0low10
midazolam0low10
oxonic acid0low10
phenindione0low10
tegafur0low10
thalidomide0low20
ticlopidine0low20
mitomycin0low10
prednisolone0low20
spironolactone0low10
aldosterone0low10
prednisone0low30
desoxycorticosterone acetate0low10
sodium citrate, anhydrous0low10
methylprednisolone0low50
pyrroles0low20
quinazolines0low10
indazoles0low10
pyrazines0low20
acetylcysteine0medium42
deoxycytidine0low240
vancomycin0low10
vidarabine0medium22
lutetium0low10
chlorine0low10
ethinyl estradiol-norgestrel combination0low10
levamisole0low10
paclitaxel0low40
etoposide0medium32
ribavirin0low10
diltiazem0low10
clopidogrel0low10
cidofovir anhydrous0low10
gemcitabine0low240
irinotecan0low10
tirofiban0low10
fluorodeoxyglucose f180low10
fluindione0low10
fibrinogen0low80
homocysteine0low40
bosentan anhydrous0low10
artesunic acid0low10
fingolimod hydrochloride0low10
imatinib mesylate0low60
glycerophosphoinositol 4,5-bisphosphate0low10
methotrexate0low50
docetaxel anhydrous0low20
levofloxacin0low10
olmesartan0low10
amotosalen0low10
angiotensin ii0low10
organophosphonates0low10
sorafenib0low40
lenalidomide0low30
bortezomib0medium61
carboplatin0medium21
fibrin0low60
pentostatin0low10
tacrolimus0medium323
cocaine0low40
mycophenolic acid0low60
decitabine0low10
melphalan0medium22
fludarabine0medium22
dermatan sulfate0low10
quinine0low40
bilirubin0low10
dinoprostone0low10
amphotericin b0low10
fondaparinux0low10
oxycodone0low20
oxymorphone0low60
sirolimus0medium143
iloprost0low10
su 112480low30
palbociclib0low10
lisinopril0low20
ramipril0low10
enalapril0low10
everolimus0low50
lenvatinib0low20
mocetinostat0low20
rivaroxaban0low10
selexipag0low10
cediranib0low10
pazopanib0low10
regorafenib0low10
carfilzomib0low200
losartan potassium0low10
ristocetin0low10
endothelin-10low10
ro13-99040low10
arginine0low10
ponatinib0low20
cardiovascular agents0low30
compstatin0low20
cabozantinib0low10
incb-0184240low10
ixazomib0low10
interleukin-80low10
apatinib0low10
hydroxocobalamin0low50
heme0low20
heparitin sulfate0low20
ascorbic acid0low10
warfarin0low30
s 1 (combination)0low10
globotriaosylceramide0low10
hyaluronoglucosaminidase0low10
vitamin b 120low150
cyclosporine0low130
thromboplastin0low50
chondroitin sulfates0low10
folic acid0low20
rifampin0low10
ganciclovir0low40
pemetrexed0low20
nintedanib0low20
defibrotide0medium72
eye0low20

Protein Targets (1,488)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
RAR-related orphan receptor gamma240024
ATAD5 protein, partial7007
GLS protein6006
Microtubule-associated protein tau100010
Smad39009
aldehyde dehydrogenase 1 family, member A1170017
thyroid stimulating hormone receptor7007
nuclear receptor subfamily 1, group I, member 3220022
progesterone receptor200020
EWS/FLI fusion protein370037
retinoic acid nuclear receptor alpha variant 1250025
retinoid X nuclear receptor alpha260026
estrogen-related nuclear receptor alpha320032
estrogen nuclear receptor alpha420042
peroxisome proliferator activated receptor gamma230023
aryl hydrocarbon receptor130013
chromobox protein homolog 1150015
thyroid hormone receptor beta isoform 2320032
peripheral myelin protein 22190019
cytochrome P450 3A4 isoform 1100010
Gamma-aminobutyric acid receptor subunit pi102012
ATP-binding cassette sub-family C member 3033033
Multidrug resistance-associated protein 4033036
Solute carrier family 22 member 60203
Carbonic anhydrase 120202
UDP-glucuronosyltransferase 1A90003
Bile salt export pump011011
Voltage-dependent calcium channel gamma-2 subunit150015
Bile salt export pump045045
Cytochrome P450 2B10001
Cytochrome P450 1A10001
Carbonic anhydrase 10405
Carbonic anhydrase 20617
Myoglobin0101
Cytochrome P450 1A10012
Cytochrome P450 1A20506
Prostaglandin G/H synthase 10202
Carbonic anhydrase 30202
Cytochrome P450 3A4016119
Cytochrome P450 2D6010010
Cytochrome P450 2C9 011011
Polyunsaturated fatty acid lipoxygenase ALOX150303
Gamma-aminobutyric acid receptor subunit beta-1102012
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit delta102012
Gamma-aminobutyric acid receptor subunit gamma-2102012
UDP-glucuronosyltransferase 1-60204
Glutamate receptor 2151016
Gamma-aminobutyric acid receptor subunit alpha-5102012
Gamma-aminobutyric acid receptor subunit alpha-3102012
Arachidonate 5-lipoxygenase-activating protein0101
UDP-glucuronosyltransferase 1A1 0306
Carbonic anhydrase 40404
Prostaglandin G/H synthase 10101
Carbonic anhydrase 60202
Gamma-aminobutyric acid receptor subunit gamma-1102012
Gamma-aminobutyric acid receptor subunit alpha-2102012
Gamma-aminobutyric acid receptor subunit alpha-4102012
Gamma-aminobutyric acid receptor subunit gamma-3102012
Gamma-aminobutyric acid receptor subunit alpha-6102012
Carbonic anhydrase 5A, mitochondrial0505
Prostaglandin G/H synthase 20168
Carbonic anhydrase 70303
Nuclear receptor ROR-gamma7007
Cytochrome P450 2J20505
Gamma-aminobutyric acid receptor subunit alpha-1102012
Gamma-aminobutyric acid receptor subunit beta-3102012
Gamma-aminobutyric acid receptor subunit beta-2102012
Carbonic anhydrase 90606
GABA theta subunit102012
Canalicular multispecific organic anion transporter 1032033
Carbonic anhydrase 150202
Carbonic anhydrase 130101
Gamma-aminobutyric acid receptor subunit epsilon102012
Carbonic anhydrase 140202
Carbonic anhydrase 5B, mitochondrial0202
toxin B0001
Chain A, JmjC domain-containing histone demethylation protein 3A6006
Chain A, 2-oxoglutarate Oxygenase100010
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
acetylcholinesterase120012
dopamine D1 receptor3003
15-lipoxygenase, partial5005
pregnane X receptor5005
phosphopantetheinyl transferase110011
USP1 protein, partial130013
NFKB1 protein, partial2002
Thrombopoietin3003
AR protein340034
regulator of G-protein signaling 43003
glucocorticoid receptor [Homo sapiens]340034
farnesoid X nuclear receptor240024
vitamin D (1,25- dihydroxyvitamin D3) receptor180018
arylsulfatase A7007
euchromatic histone-lysine N-methyltransferase 2220022
Bloom syndrome protein isoform 16006
D(1A) dopamine receptor3003
thyroid hormone receptor beta isoform a8008
heat shock protein beta-18008
flap endonuclease 13003
geminin360036
survival motor neuron protein isoform d9009
muscarinic acetylcholine receptor M14004
Histone deacetylase 30606
Histone deacetylase 40404
Guanine nucleotide-binding protein G3003
Histone deacetylase 10606
Histone deacetylase 70404
Histone deacetylase 20606
Polyamine deacetylase HDAC100303
Histone deacetylase 11 0404
Ataxin-2220022
Histone deacetylase 80505
Histone deacetylase 60606
Histone deacetylase 90303
Histone deacetylase 50404
ATP-dependent phosphofructokinase7007
nuclear factor erythroid 2-related factor 2 isoform 2140014
Sex hormone-binding globulin0011
Corticosteroid-binding globulin0202
Mineralocorticoid receptor 0539
Androgen receptor0607
Mineralocorticoid receptor0101
Solute carrier organic anion transporter family member 1A10204
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)6006
cytochrome P450 2D6180018
glucocerebrosidase5005
cytochrome P450 2D6 isoform 12002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor5005
lamin isoform A-delta10230023
Rap guanine nucleotide exchange factor 32002
Lysosomal acid glucosylceramidase0101
Sodium-dependent serotonin transporter0808
TAR DNA-binding protein 434004
Chain A, Ferritin light chain7007
acid sphingomyelinase3003
TDP1 protein360036
cytochrome P450 family 3 subfamily A polypeptide 4300030
G170017
IDH1120012
NEDD8-activating enzyme E1 regulatory subunit isoform a0101
NEDD8-conjugating enzyme Ubc120101
nuclear receptor ROR-gamma isoform 1100010
histone acetyltransferase KAT2A isoform 19009
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Potassium channel subfamily K member 20314
Interferon beta280028
HLA class I histocompatibility antigen, B alpha chain 170017
ATP-dependent translocase ABCB1011117
Alpha-2A adrenergic receptor0808
Alpha-2C adrenergic receptor0909
Alpha-2B adrenergic receptor0303
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Alpha-2C adrenergic receptor0303
Alpha-2A adrenergic receptor0303
Alpha-1D adrenergic receptor0505
Alpha-1A adrenergic receptor0101
Alpha-1B adrenergic receptor0101
5-hydroxytryptamine receptor 60505
Spike glycoprotein250328
Sodium-dependent dopamine transporter 0808
Voltage-dependent L-type calcium channel subunit alpha-1C0404
Potassium channel subfamily K member 2 0101
Inositol hexakisphosphate kinase 1170017
cytochrome P450 2C9, partial170017
Chain A, HADH2 protein8008
Chain B, HADH2 protein8008
Chain A, Cruzipain5005
interleukin 84004
peroxisome proliferator-activated receptor delta150015
tumor necrosis factor1001
vitamin D3 receptor isoform VDRA9009
nuclear factor erythroid 2-related factor 2 isoform 1240024
Cytochrome P450 2C190909
Potassium voltage-gated channel subfamily H member 2018019
Aurora kinase B021315
Broad substrate specificity ATP-binding cassette transporter ABCG209010
DNA polymerase kappa isoform 17007
Atrial natriuretic peptide receptor 30101
Type-1A angiotensin II receptor 0325
Type-1 angiotensin II receptor0011
Type-1B angiotensin II receptor0404
Type-1 angiotensin II receptor0427
Type-2 angiotensin II receptor0505
Type-2 angiotensin II receptor0303
Vascular endothelial growth factor receptor 2015826
Chain A, Hyaluronidase, phage associated0101
GLI family zinc finger 3260026
thioredoxin glutathione reductase6006
lethal(3)malignant brain tumor-like protein 1 isoform I1001
lethal factor (plasmid)3003
Polyphenol oxidase 20101
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0718
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE150015
Chain A, TYROSYL-DNA PHOSPHODIESTERASE9009
thioredoxin reductase120012
SMAD family member 26006
Fumarate hydratase170017
SMAD family member 36006
pregnane X nuclear receptor250025
polyprotein170017
P532002
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a190019
thyroid stimulating hormone receptor7007
activating transcription factor 6100010
v-jun sarcoma virus 17 oncogene homolog (avian)7007
Histone H2A.x9009
peripheral myelin protein 22 isoform 13003
hemoglobin subunit beta1001
cellular tumor antigen p53 isoform a4004
DNA polymerase iota isoform a (long)9009
M-phase phosphoprotein 82002
muscleblind-like protein 1 isoform 14004
Cellular tumor antigen p53260026
ATPase family AAA domain-containing protein 5190019
Protein-arginine deiminase type-40303
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
caspase-1 isoform alpha precursor2002
Caspase-72002
Inositol monophosphatase 11001
Solute carrier organic anion transporter family member 1B308012
Solute carrier organic anion transporter family member 1B108011
Chain H, Proteasome component PUP10101
Chain I, Proteasome component PUP30101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Proteasome subunit beta type-110303
PPM1D protein190019
caspase 7, apoptosis-related cysteine protease7007
estrogen receptor 2 (ER beta)140014
caspase-37007
nuclear receptor subfamily 1, group I, member 28008
Caspase-74004
caspase-34004
26S proteasome non-ATPase regulatory subunit 110202
26S proteasome non-ATPase regulatory subunit 120202
26S proteasome non-ATPase regulatory subunit 140202
Proteasome subunit alpha type-70303
26S proteasome non-ATPase regulatory subunit 30202
Prothrombin0203
Chymotrypsinogen A0101
Cathepsin B0202
Neutrophil elastase0101
Cathepsin G0303
Lysosomal protective protein0202
Chymotrypsinogen B0101
26S proteasome regulatory subunit 6A0202
Nuclear factor NF-kappa-B p105 subunit0101
Proteasome subunit beta type-10304
Chymase0101
Proteasome subunit alpha type-10303
Proteasome subunit alpha type-20303
Proteasome subunit alpha type-30303
Proteasome subunit alpha type-40303
Proteasome subunit beta type-80303
Proteasome subunit beta type-80101
Proteasome subunit beta type-90303
Proteasome subunit alpha type-50303
Proteasome subunit beta type-40303
Proteasome subunit beta type-60303
Proteasome subunit beta type-50405
26S proteasome regulatory subunit 70202
Lon protease homolog, mitochondrial0101
Proteasome subunit beta type-100303
26S proteasome regulatory subunit 6B021315
26S proteasome non-ATPase regulatory subunit 80202
Proteasome subunit beta type-30303
Proteasome subunit beta type-20304
26S proteasome non-ATPase regulatory subunit 70202
26S proteasome non-ATPase regulatory subunit 40202
26S proteasome complex subunit SEM10202
Proteasome subunit alpha type-60303
26S proteasome regulatory subunit 40202
26S proteasome regulatory subunit 80202
26S proteasome regulatory subunit 10B0202
Beta-carbonic anhydrase 10101
Nuclear factor NF-kappa-B p100 subunit 0101
Transcription factor p650101
26S proteasome non-ATPase regulatory subunit 20202
26S proteasome non-ATPase regulatory subunit 60202
Proteasomal ubiquitin receptor ADRM10202
ATP-dependent Clp protease proteolytic subunit0224
Carbonic anhydrase 130101
NACHT, LRR and PYD domains-containing protein 3 0202
Proteasome subunit alpha-type 80303
Proteasome subunit beta type-70303
26S proteasome non-ATPase regulatory subunit 10202
26S proteasome non-ATPase regulatory subunit 130202
Nuclear receptor subfamily 1 group I member 20055
Endothelin receptor type B1102
Endothelin receptor type B0213
Endothelin-1 receptor0303
Endothelin-1 receptor1214
Endothelin receptor type B0011
Deoxyhypusine synthase0101
Sodium/bile acid cotransporter0101
Endothelin-1 receptor0101
apical membrane antigen 1, AMA11001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
Matrix metalloproteinase-90101
Disintegrin and metalloproteinase domain-containing protein 172002
tyrosine-protein kinase Yes120012
Bone morphogenetic protein receptor type-1B001313
Membrane-associated progesterone receptor component 10077
Cell division cycle 7-related protein kinase0088
Serine/threonine-protein kinase PLK4021315
ATP-dependent RNA helicase DDX3X001313
Pyridoxal kinase001313
Citron Rho-interacting kinase001313
Serine/threonine-protein kinase Chk1021315
Aurora kinase A021315
Cyclin-G-associated kinase011314
Ephrin type-B receptor 6001313
Peroxisomal acyl-coenzyme A oxidase 3001313
Receptor-interacting serine/threonine-protein kinase 2021315
Mitotic checkpoint serine/threonine-protein kinase BUB1001313
Dynamin-like 120 kDa protein, mitochondrial001313
Tyrosine-protein kinase JAK2031013
Eukaryotic translation initiation factor 5B0088
Rho-associated protein kinase 2001313
Serine/threonine-protein kinase ULK1001313
Serine/threonine-protein kinase/endoribonuclease IRE1001313
Ribosomal protein S6 kinase alpha-5001313
U5 small nuclear ribonucleoprotein 200 kDa helicase001313
Ribosomal protein S6 kinase alpha-4001313
Serine/threonine-protein kinase 16001313
Serine/threonine-protein kinase 10001313
Serine/threonine-protein kinase D3001313
Structural maintenance of chromosomes protein 2001313
Mitogen-activated protein kinase kinase kinase 6001212
Mitogen-activated protein kinase kinase kinase kinase 4001313
Serine/threonine-protein kinase LATS1001313
Serine/threonine-protein kinase PAK 4021315
Tyrosine-protein kinase ABL1091727
Epidermal growth factor receptor081321
High affinity nerve growth factor receptor021113
Guanine nucleotide-binding protein G(i) subunit alpha-2001010
ADP/ATP translocase 2001313
Protein kinase C beta type001313
Insulin receptor031316
Tyrosine-protein kinase Lck041317
Tyrosine-protein kinase Fyn031316
Cyclin-dependent kinase 1041317
Glycogen phosphorylase, liver form001313
Acyl-CoA desaturase 10101
Tyrosine-protein kinase Fes/Fps001313
Adenine phosphoribosyltransferase0099
Tyrosine-protein kinase Yes011314
Tyrosine-protein kinase Lyn021315
Proto-oncogene tyrosine-protein kinase receptor Ret091322
Insulin-like growth factor 1 receptor031316
Signal recognition particle receptor subunit alpha001111
Cytochrome c1, heme protein, mitochondrial001313
Hepatocyte growth factor receptor041318
Tyrosine-protein kinase HCK031316
Platelet-derived growth factor receptor beta0121325
Serine/threonine-protein kinase A-Raf011314
Mast/stem cell growth factor receptor Kit011819
Glycogen phosphorylase, brain form001313
Breakpoint cluster region protein031620
Serine/threonine-protein kinase pim-1001313
Fibroblast growth factor receptor 10101324
Cyclin-dependent kinase 4041317
ADP/ATP translocase 3001313
Inosine-5'-monophosphate dehydrogenase 2021214
Proto-oncogene tyrosine-protein kinase Src071320
cAMP-dependent protein kinase type II-alpha regulatory subunit001313
Serine/threonine-protein kinase B-raf041418
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform001313
Ribosyldihydronicotinamide dehydrogenase [quinone]001313
Platelet-derived growth factor receptor alpha011718
Tyrosine-protein kinase Fer001313
Protein kinase C alpha type001313
cAMP-dependent protein kinase catalytic subunit alpha011314
Vascular endothelial growth factor receptor 1 010616
General transcription and DNA repair factor IIH helicase subunit XPD001313
Casein kinase II subunit alpha'001313
Ras-related protein Rab-6A001111
Multifunctional protein ADE2001313
cAMP-dependent protein kinase catalytic subunit gamma001111
cAMP-dependent protein kinase catalytic subunit beta001313
Ferrochelatase, mitochondrial001313
Ribosomal protein S6 kinase beta-1001212
Tyrosine-protein kinase JAK1031417
Cyclin-dependent kinase 2061420
Beta-adrenergic receptor kinase 1001313
Probable ATP-dependent RNA helicase DDX6001313
Mitogen-activated protein kinase 3 011314
MAP/microtubule affinity-regulating kinase 3001313
Deoxycytidine kinase001315
Mitogen-activated protein kinase 1011314
Ephrin type-A receptor 2011314
Ephrin type-B receptor 2001313
Non-receptor tyrosine-protein kinase TYK2021416
UMP-CMP kinase 0077
Phosphatidylethanolamine-binding protein 1001010
Wee1-like protein kinase001313
Heme oxygenase 2001313
Tyrosine-protein kinase receptor UFO0268
S-adenosylmethionine synthase isoform type-2001313
DnaJ homolog subfamily A member 1001313
RAC-alpha serine/threonine-protein kinase021315
RAC-beta serine/threonine-protein kinase001313
Kinesin-1 heavy chain0303
Dual specificity protein kinase TTK001111
DNA replication licensing factor MCM4001313
Myosin-10001212
Vascular endothelial growth factor receptor 309615
Dual specificity mitogen-activated protein kinase kinase 2001313
Receptor-type tyrosine-protein kinase FLT3081322
Bone morphogenetic protein receptor type-1A001313
Activin receptor type-1B001313
TGF-beta receptor type-1001313
TGF-beta receptor type-2001313
Electron transfer flavoprotein subunit beta001010
Tyrosine-protein kinase CSK011314
Glycine--tRNA ligase001313
Protein kinase C iota type001313
Exosome RNA helicase MTR4001313
Tyrosine-protein kinase Tec001313
Tyrosine-protein kinase ABL2001313
Tyrosine-protein kinase FRK011314
Tyrosine-protein kinase SYK001313
Mitogen-activated protein kinase 8001313
Mitogen-activated protein kinase 9001313
Dual specificity mitogen-activated protein kinase kinase 3001313
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha001212
Casein kinase I isoform alpha021315
Casein kinase I isoform delta001313
MAP kinase-activated protein kinase 2001313
Elongation factor Tu, mitochondrial001313
Cysteine--tRNA ligase, cytoplasmic001111
Casein kinase I isoform epsilon001313
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial001313
Dual specificity protein kinase CLK1001313
Dual specificity protein kinase CLK2001313
Dual specificity protein kinase CLK3001212
Glycogen synthase kinase-3 alpha001313
Glycogen synthase kinase-3 beta021315
Cyclin-dependent kinase 7021315
Cyclin-dependent kinase 9021315
Ras-related protein Rab-27A001313
Interleukin-1 receptor-associated kinase 1001313
Ribosomal protein S6 kinase alpha-3011314
Serine/threonine-protein kinase Nek2011314
Serine/threonine-protein kinase Nek3001313
Dual specificity mitogen-activated protein kinase kinase 6001313
Serine/threonine-protein kinase PLK1041115
LIM domain kinase 1001313
LIM domain kinase 2001313
Mitogen-activated protein kinase 10001313
Tyrosine--tRNA ligase, cytoplasmic001212
5'-AMP-activated protein kinase subunit gamma-1001313
Ephrin type-B receptor 3001313
Ephrin type-A receptor 5001313
Ephrin type-B receptor 4021315
Ephrin type-A receptor 4001313
Adenylate kinase 2, mitochondrial001313
Adenosine kinase001313
Ras-related protein Rab-10001313
Actin-related protein 3001313
Actin-related protein 2001313
GTP-binding nuclear protein Ran001313
Casein kinase I isoform gamma-2001212
Cyclin-dependent kinase 3001111
Cyclin-dependent kinase 6031316
Cyclin-dependent-like kinase 5 011314
Cyclin-dependent kinase 16001313
Cyclin-dependent kinase 17001313
ATP-dependent 6-phosphofructokinase, platelet type001313
Dual specificity mitogen-activated protein kinase kinase 1011314
Angiopoietin-1 receptor04610
DNA topoisomerase 2-beta011421
Protein kinase C theta type001212
Activin receptor type-1001313
Macrophage-stimulating protein receptor011314
Focal adhesion kinase 1011314
Protein kinase C zeta type0066
Protein kinase C delta type001313
Tyrosine-protein kinase BTK001313
Activated CDC42 kinase 1001313
Epithelial discoidin domain-containing receptor 1011314
Mitogen-activated protein kinase kinase kinase kinase 2001313
Serine/threonine-protein kinase 4001313
5'-AMP-activated protein kinase catalytic subunit alpha-1011314
Dual specificity mitogen-activated protein kinase kinase 5001313
Mitogen-activated protein kinase 7001313
Serine/threonine-protein kinase PAK 2001212
Serine/threonine-protein kinase 3001313
Mitogen-activated protein kinase kinase kinase 1001313
Integrin-linked protein kinase001313
Rho-associated protein kinase 1001313
Non-receptor tyrosine-protein kinase TNK1001313
Calcium/calmodulin-dependent protein kinase type II subunit gamma001313
Calcium/calmodulin-dependent protein kinase type II subunit delta001313
Dual specificity tyrosine-phosphorylation-regulated kinase 1A001313
Activin receptor type-2B001313
Bone morphogenetic protein receptor type-2001313
Protein-tyrosine kinase 6001313
cGMP-dependent protein kinase 1 001212
Cyclin-dependent kinase 13001313
Inhibitor of nuclear factor kappa-B kinase subunit epsilon001313
Protein-tyrosine kinase 2-beta001313
Maternal embryonic leucine zipper kinase021315
Structural maintenance of chromosomes protein 1A001212
Chromodomain-helicase-DNA-binding protein 4001212
Peroxisomal acyl-coenzyme A oxidase 1001212
Ephrin type-A receptor 70099
Delta(24)-sterol reductase001313
Ribosomal protein S6 kinase alpha-1011314
Myosin light chain kinase, smooth muscle001313
Mitogen-activated protein kinase 11001313
Serine/threonine-protein kinase STK11001313
Coiled-coil domain-containing protein 60404
Serine/threonine-protein kinase N1001313
Serine/threonine-protein kinase N2001313
Mitogen-activated protein kinase 14021315
Calcium/calmodulin-dependent protein kinase type IV001313
Mitogen-activated protein kinase kinase kinase 11001313
Discoidin domain-containing receptor 2021315
AP2-associated protein kinase 1021315
Myosin light chain kinase 3001212
Putative heat shock protein HSP 90-beta 2001212
Rab-like protein 30088
Serine/threonine-protein kinase MRCK alpha001313
Serine/threonine-protein kinase MRCK gamma001313
Acyl-CoA dehydrogenase family member 10001212
Serine/threonine-protein kinase ULK3001313
Uncharacterized protein FLJ45252001313
Acyl-CoA dehydrogenase family member 11001313
Serine/threonine-protein kinase/endoribonuclease IRE2001212
Serine/threonine-protein kinase MARK2001313
ATP-dependent RNA helicase DHX300099
Serine/threonine-protein kinase TAO1001313
STE20-related kinase adapter protein alpha001313
Myosin-14001313
AarF domain-containing protein kinase 1001313
ATP-dependent RNA helicase DDX420099
Mitogen-activated protein kinase kinase kinase kinase 3001313
MAP kinase-activated protein kinase 5001212
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0033
Atypical kinase COQ8A, mitochondrial001313
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma001313
Mitogen-activated protein kinase 15001313
Serine/threonine-protein kinase Nek9001313
Serine/threonine-protein kinase Nek7001010
ATP-dependent RNA helicase DDX1001313
Mitogen-activated protein kinase kinase kinase kinase 1001313
MAP/microtubule affinity-regulating kinase 4001313
Serine/threonine-protein kinase Nek1001313
Calcium/calmodulin-dependent protein kinase kinase 2001313
EKC/KEOPS complex subunit TP53RK001313
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase001313
Mitogen-activated protein kinase kinase kinase 5001313
Mitogen-activated protein kinase kinase kinase 3001313
Eukaryotic translation initiation factor 2-alpha kinase 1001313
Nucleolar GTP-binding protein 1001212
Serine/threonine-protein kinase D2001313
NUAK family SNF1-like kinase 2001212
RNA cytidine acetyltransferase001313
Serine/threonine-protein kinase SIK2001313
STE20-like serine/threonine-protein kinase 001313
Serine/threonine-protein kinase TAO3001313
dCTP pyrophosphatase 1001313
Dual specificity protein kinase CLK4001212
Casein kinase I isoform gamma-1001313
Serine/threonine-protein kinase PAK 601910
Phenylalanine--tRNA ligase beta subunit001313
Isoleucine--tRNA ligase, mitochondrial001010
BMP-2-inducible protein kinase001313
Obg-like ATPase 1001010
Midasin001313
SAFB-like transcription modulator0101
Interleukin-1 receptor-associated kinase 4001313
Mitogen-activated protein kinase kinase kinase 20001313
Cyclin-dependent kinase 12001313
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13001212
Serine/threonine-protein kinase 26001313
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial001212
Serine/threonine-protein kinase NLK001313
5'-AMP-activated protein kinase subunit gamma-2001313
Serine/threonine-protein kinase TBK1011314
Septin-9001313
Ribosomal protein S6 kinase alpha-6001313
TRAF2 and NCK-interacting protein kinase001313
Serine/threonine-protein kinase TAO2001313
Long-chain-fatty-acid--CoA ligase 5001111
ALK tyrosine kinase receptor0178
Serine/threonine-protein kinase ICK001212
RAC-gamma serine/threonine-protein kinase001313
Serine/threonine-protein kinase SIK3001313
Mitogen-activated protein kinase kinase kinase 2001313
Thyroid hormone receptor-associated protein 30099
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0099
Mitogen-activated protein kinase kinase kinase kinase 5001313
Receptor-interacting serine/threonine-protein kinase 3021315
Serine/threonine-protein kinase MRCK beta001313
Interleukin-1 receptor-associated kinase 3001313
Serine/threonine-protein kinase 24001111
Casein kinase I isoform gamma-3001313
Mitogen-activated protein kinase kinase kinase 4001313
potassium voltage-gated channel subfamily H member 2 isoform d6006
Receptor tyrosine-protein kinase erbB-204610
Aldo-keto reductase family 1 member B10707
60 kDa chaperonin0202
Adenosine receptor A30303
60 kDa heat shock protein, mitochondrial0404
Beta-3 adrenergic receptor0415
Alpha-1B adrenergic receptor0303
5-hydroxytryptamine receptor 1A0404
Sodium-dependent noradrenaline transporter 0808
Thromboxane-A synthase 0101
Type-1 angiotensin II receptor0101
Alpha-1A adrenergic receptor0303
10 kDa heat shock protein, mitochondrial0404
Thiosulfate sulfurtransferase0404
60 kDa chaperonin 0404
10 kDa chaperonin 0404
Leukotriene B4 receptor 20112
histone-lysine N-methyltransferase 2A isoform 2 precursor3003
Proteasome subunit beta type-20101
Proteasome subunit beta type-10101
Glutathione S-transferase omega-10202
bromodomain adjacent to zinc finger domain 2B3003
lysosomal alpha-glucosidase preproprotein2002
mitogen-activated protein kinase 13003
serine/threonine-protein kinase mTOR isoform 12002
short transient receptor potential channel 6 isoform 10011
Toll-like receptor 40202
Solute carrier family 22 member 20305
Solute carrier family 22 member 1 09011
5-hydroxytryptamine receptor 40202
Amyloid-beta precursor protein0202
Beta-2 adrenergic receptor0213
Beta-1 adrenergic receptor0213
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
Angiotensin-converting enzyme0606
D(2) dopamine receptor0202
D(1A) dopamine receptor0202
5-hydroxytryptamine receptor 2A0303
5-hydroxytryptamine receptor 2C0303
5-hydroxytryptamine receptor 1B0303
D(3) dopamine receptor0202
5-hydroxytryptamine receptor 2B0303
D(1A) dopamine receptor1001
Potassium channel subfamily K member 100101
Cytochrome P450 1B10101
Nuclear receptor subfamily 3 group C member 3 0202
Multidrug and toxin extrusion protein 10505
Leukotriene C4 synthase0066
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform0369
Serine/threonine-protein kinase 250066
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta0066
Serine/threonine-protein kinase RIO30066
Dual specificity mitogen-activated protein kinase kinase 70066
Inhibitor of nuclear factor kappa-B kinase subunit beta0066
Peripheral plasma membrane protein CASK0066
Serine/threonine-protein kinase DCLK10066
Inhibitor of nuclear factor kappa-B kinase subunit alpha0066
Muscle, skeletal receptor tyrosine-protein kinase0066
Mitogen-activated protein kinase 130066
3-phosphoinositide-dependent protein kinase 10066
Mitogen-activated protein kinase kinase kinase 130066
Death-associated protein kinase 30066
Mitogen-activated protein kinase kinase kinase 70066
NUAK family SNF1-like kinase 10268
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma0066
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma0066
Serine/threonine-protein kinase PAK 30066
Cyclin-dependent kinase-like 50088
Serine/threonine-protein kinase 17B0066
Cyclin-dependent kinase 140066
Serine/threonine-protein kinase OSR10066
Serine/threonine-protein kinase Chk20167
RAF proto-oncogene serine/threonine-protein kinase04610
Macrophage colony-stimulating factor 1 receptor05611
Proto-oncogene tyrosine-protein kinase ROS0066
Tyrosine-protein kinase Fgr001010
Wee1-like protein kinase 20066
Uncharacterized serine/threonine-protein kinase SBK30066
DNA topoisomerase 2-alpha021222
Insulin receptor-related protein0066
Interferon-induced, double-stranded RNA-activated protein kinase0066
Serine/threonine-protein kinase MAK0066
Cyclin-dependent kinase 11B0066
Ephrin type-A receptor 1011112
Fibroblast growth factor receptor 20369
Receptor tyrosine-protein kinase erbB-30066
Fibroblast growth factor receptor 40268
Fibroblast growth factor receptor 30268
Protein kinase C eta type0066
Activin receptor type-2A0066
Ephrin type-A receptor 30066
Ephrin type-A receptor 80066
Leukocyte tyrosine kinase receptor0167
Mitogen-activated protein kinase 40066
G protein-coupled receptor kinase 40066
Tyrosine-protein kinase receptor Tie-10066
Serine/threonine-protein kinase receptor R30088
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0268
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0268
Serine/threonine-protein kinase mTOR05813
Megakaryocyte-associated tyrosine-protein kinase0066
Tyrosine-protein kinase TXK0066
G protein-coupled receptor kinase 6001010
Tyrosine-protein kinase ZAP-700066
Dual specificity mitogen-activated protein kinase kinase 40077
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0268
Cyclin-dependent kinase 80167
Choline-phosphate cytidylyltransferase A0077
Tyrosine-protein kinase Blk0066
Cytoplasmic tyrosine-protein kinase BMX0066
cAMP-dependent protein kinase catalytic subunit PRKX0066
Serine/threonine-protein kinase Nek40066
Tyrosine-protein kinase JAK30369
Death-associated protein kinase 10066
Mitogen-activated protein kinase 120066
5'-AMP-activated protein kinase catalytic subunit alpha-20167
Ephrin type-B receptor 10066
Hormonally up-regulated neu tumor-associated kinase0066
Serine/threonine-protein kinase SIK10066
Receptor-interacting serine/threonine-protein kinase 40066
Cell division control protein 2 homolog0066
Calcium-dependent protein kinase 10066
Casein kinase II subunit alpha0066
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta0066
SRSF protein kinase 20066
Mitogen-activated protein kinase kinase kinase 90066
Serine/threonine-protein kinase PknB0066
Cyclin-dependent kinase-like 10066
Protein kinase C epsilon type0066
Mitogen-activated protein kinase kinase kinase 100066
Tyrosine-protein kinase receptor TYRO30066
Cyclin-dependent kinase 180088
Tyrosine-protein kinase ITK/TSK0066
Myotonin-protein kinase0066
Mitogen-activated protein kinase kinase kinase 120066
Tyrosine-protein kinase Mer02810
Serine/threonine-protein kinase PAK 10066
cGMP-dependent protein kinase 20066
Serine/threonine-protein kinase PRP4 homolog0066
Serine/threonine-protein kinase ATR0044
Receptor-interacting serine/threonine-protein kinase 10369
Calcium/calmodulin-dependent protein kinase type II subunit beta0066
Calcium/calmodulin-dependent protein kinase type 10066
Serine/threonine-protein kinase D10066
Serine/threonine-protein kinase 380077
Receptor tyrosine-protein kinase erbB-40066
Ribosomal protein S6 kinase alpha-20066
Dual specificity testis-specific protein kinase 1001111
Rhodopsin kinase GRK10066
NT-3 growth factor receptor0066
BDNF/NT-3 growth factors receptor0066
Mitogen-activated protein kinase 60066
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform0066
Uncharacterized aarF domain-containing protein kinase 50066
Serine/threonine-protein kinase SBK10066
Mitogen-activated protein kinase kinase kinase 190066
Serine/threonine-protein kinase TNNI3K0167
Leucine-rich repeat serine/threonine-protein kinase 20268
Serine/threonine-protein kinase Nek50066
Serine/threonine-protein kinase N3001111
Dual serine/threonine and tyrosine protein kinase0066
Mitogen-activated protein kinase kinase kinase 150066
Serine/threonine-protein kinase tousled-like 20066
Serine/threonine-protein kinase 32C0066
Serine/threonine-protein kinase pim-30066
Serine/threonine-protein kinase VRK20066
Myosin light chain kinase family member 40066
Homeodomain-interacting protein kinase 10167
Calcium/calmodulin-dependent protein kinase type 1D0066
Cyclin-dependent kinase-like 30066
Serine/threonine-protein kinase BRSK20066
Serine/threonine-protein kinase NIM10066
Serine/threonine-protein kinase ULK20066
Misshapen-like kinase 10099
Serine/threonine-protein kinase DCLK20066
Calcium/calmodulin-dependent protein kinase kinase 10066
Casein kinase I isoform alpha-like0066
Homeodomain-interacting protein kinase 40167
Myosin-IIIa0066
Ankyrin repeat and protein kinase domain-containing protein 10066
Serine/threonine-protein kinase Nek110066
Serine/threonine-protein kinase BRSK10066
Serine/threonine-protein kinase 350066
Rhodopsin kinase GRK70066
Serine/threonine-protein kinase 32A0066
Myosin-IIIb0066
Dual specificity tyrosine-phosphorylation-regulated kinase 20066
Cyclin-dependent kinase-like 20066
Serine/threonine-protein kinase Sgk30066
Atypical kinase COQ8B, mitochondrial0066
Calcium/calmodulin-dependent protein kinase type 1G0077
Cyclin-dependent kinase 150066
PAS domain-containing serine/threonine-protein kinase001111
Dual specificity testis-specific protein kinase 20077
SRSF protein kinase 10066
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha0066
Serine/threonine-protein kinase RIO10066
MAP kinase-interacting serine/threonine-protein kinase 10066
Serine/threonine-protein kinase RIO20066
Cyclin-dependent kinase 190167
Transient receptor potential cation channel subfamily M member 60066
Testis-specific serine/threonine-protein kinase 10066
Serine/threonine-protein kinase 330066
Serine/threonine-protein kinase DCLK30066
Myosin light chain kinase 2, skeletal/cardiac muscle0066
Homeodomain-interacting protein kinase 20167
Tyrosine-protein kinase Srms0066
Homeodomain-interacting protein kinase 30167
Serine/threonine-protein kinase PLK30268
MAP kinase-interacting serine/threonine-protein kinase 20167
Serine/threonine-protein kinase Nek60066
SNF-related serine/threonine-protein kinase0066
Serine/threonine-protein kinase LATS20066
Serine/threonine-protein kinase 360066
Serine/threonine-protein kinase 32B0066
Serine/threonine-protein kinase PLK20268
Serine/threonine-protein kinase MARK10066
Serine/threonine-protein kinase pim-20099
Serine/threonine-protein kinase PAK 50167
eIF-2-alpha kinase GCN20066
Phosphatidylinositol 4-kinase beta0066
Serine/threonine-protein kinase 17A0066
STE20/SPS1-related proline-alanine-rich protein kinase0066
Ephrin type-A receptor 60066
Death-associated protein kinase 20066
Serine/threonine-protein kinase tousled-like 10066
SRSF protein kinase 30066
Cyclin-dependent kinase 11A0066
Aurora kinase C0066
Calcium/calmodulin-dependent protein kinase type II subunit alpha0066
Serine/threonine-protein kinase 38-like0088
Microtubule-associated serine/threonine-protein kinase 10066
Thymidine kinase 0202
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Thymidine kinase0001
Solute carrier family 22 member 60105
cytochrome P450 2C9 precursor2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 15005
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit B0102
DNA gyrase subunit A0103
DNA gyrase subunit B0103
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0102
DNA gyrase subunit A0102
Multidrug resistance protein MdtK0011
Histamine H2 receptor4004
DNA gyrase subunit B0202
DNA gyrase subunit A0303
Enoyl-[acyl-carrier-protein] reductase [NADH]0102
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Integrase 0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50101
perilipin-10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
Beta-lactamase0101
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0001
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
nonstructural protein 14004
Cytochrome P450 2C80203
Cytochrome P450 2B60314
Liver carboxylesterase 10104
Rap guanine nucleotide exchange factor 41001
P2Y purinoceptor 120101
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M10101
5-hydroxytryptamine receptor 2C0304
Tryptophan 5-hydroxylase 10101
5-hydroxytryptamine receptor 2A0303
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
D0101
Sodium-dependent dopamine transporter0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0202
Gamma-aminobutyric acid receptor subunit beta-30101
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0202
5-hydroxytryptamine receptor 60101
Gamma-aminobutyric acid receptor subunit alpha-50101
Sodium-dependent serotonin transporter0607
5-hydroxytryptamine receptor 7 0101
Gamma-aminobutyric acid receptor subunit alpha-30101
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
Glutamate receptor ionotropic, NMDA 1 0315
5-hydroxytryptamine receptor 3A0101
Lysosomal Pro-X carboxypeptidase0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
D(2) dopamine receptor0101
Gamma-aminobutyric acid receptor subunit epsilon0101
Glutamate receptor ionotropic, NMDA 2A 0315
Glutamate receptor ionotropic, NMDA 2B0315
Glutamate receptor ionotropic, NMDA 2C0315
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
Leukotriene B4 receptor 10101
Gamma-aminobutyric acid receptor subunit alpha-60101
Sodium-dependent dopamine transporter0202
Glutamate receptor ionotropic, NMDA 2D0315
5-hydroxytryptamine receptor 4 0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Glutamate receptor ionotropic, NMDA 3B0315
Sigma non-opioid intracellular receptor 10606
Gamma-aminobutyric acid receptor subunit gamma-30101
5-hydroxytryptamine receptor 3B0101
Glutamate receptor ionotropic, NMDA 3A0315
Gamma-aminobutyric acid receptor subunit theta0101
Transporter0303
Complement factor B0101
Complement C30101
Sodium- and chloride-dependent creatine transporter 10101
Proton-coupled amino acid transporter 10202
Deoxycytidine kinase0001
Chain A, Beta-lactamase8008
67.9K protein130013
exodeoxyribonuclease V subunit RecD0101
exodeoxyribonuclease V subunit RecB0101
exodeoxyribonuclease V subunit RecC0101
DNA (cytosine-5)-methyltransferase 10101
Histone-lysine N-methyltransferase EHMT20101
Thymidine kinase 2 0101
Probable deoxycytidylate deaminase0001
Cytidine deaminase0002
AAA family ATPase 0002
Reverse transcriptase/RNaseH 0123
glp-1 receptor, partial9009
huntingtin isoform 23003
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Voltage-dependent L-type calcium channel subunit alpha-1F0303
Voltage-dependent L-type calcium channel subunit alpha-1D0202
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0101
5-hydroxytryptamine receptor 70202
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Potassium voltage-gated channel subfamily A member 10101
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Sodium channel protein type 5 subunit alpha0303
Sodium channel protein type 9 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Sodium channel protein type 10 subunit alpha0101
prostaglandin E2 receptor EP2 subtype1001
Solute carrier organic anion transporter family member 1A50001
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Prostaglandin E2 receptor EP1 subtype0224
Prostaglandin E2 receptor EP1 subtype0101
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin F2-alpha receptor0011
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP3 subtype0314
Prostaglandin E2 receptor EP2 subtype0224
Prostacyclin receptor0538
Solute carrier organic anion transporter family member 2A10002
Solute carrier family 22 member 70001
Prostaglandin E2 receptor EP2 subtype0101
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 200202
Solute carrier family 22 member 80002
Solute carrier family 22 member 60202
Solute carrier family 22 member 70001
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 110002
Solute carrier organic anion transporter family member 1B20001
Solute carrier family 22 member 70001
Serum paraoxonase/arylesterase 10404
Kinesin-like protein KIF110101
Nucleotide-binding oligomerization domain-containing protein 20202
endonuclease IV2002
Angiotensin-converting enzyme 0404
Succinyl-diaminopimelate desuccinylase0101
Solute carrier family 15 member 10101
Angiotensin-converting enzyme0202
Solute carrier family 15 member 10101
Angiotensin-converting enzyme 2 0134
hypoxia-inducible factor 1 alpha subunit5005
LMP1 [Human herpesvirus 4]0001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0202
urokinase-type plasminogen activator precursor8008
plasminogen precursor8008
urokinase plasminogen activator surface receptor precursor8008
transactivating tegument protein VP16 [Human herpesvirus 1]0202
nuclear receptor coactivator 3 isoform a0202
Regulatory protein E20011
ATP-dependent translocase ABCB10202
DNA topoisomerase 10103
DNA topoisomerase 20001
ATP-dependent translocase ABCB10303
Caspase-30101
DNA topoisomerase 2-alpha 0001
Tubulin beta-2B chain0114
Similar to alpha-tubulin isoform 1 0114
Similar to alpha-tubulin isoform 1 0103
Potassium voltage-gated channel subfamily E member 10202
Potassium voltage-gated channel subfamily KQT member 10202
Regulatory-associated protein of mTOR0202
Target of rapamycin complex subunit LST80202
Potassium voltage-gated channel subfamily D member 30202
Sphingosine 1-phosphate receptor 10011
RCG53912, isoform CRA_a 0001
Sphingosine kinase 1 0001
Sphingosine kinase 20001
Sphingosine kinase 10001
corticotropin-releasing hormone receptor 20112
corticotropin releasing factor-binding protein0112
glycogen synthase kinase-3 beta isoform 10033
5'-nucleotidase0101
Adenosine receptor A30101
Adenosine deaminase 0103
Chain A, Dihydrofolate reductase0011
alpha-galactosidase3003
DNA polymerase beta3003
Thymidylate synthase0606
Thymidylate synthase0404
Dihydrofolate reductase0336
Aldo-keto reductase family 1 member B10101
Alpha-synuclein4105
Folylpolyglutamate synthase, mitochondrial0104
Solute carrier organic anion transporter family member 1A30102
Folylpolyglutamate synthase, mitochondrial0104
Multidrug resistance associated protein0103
Coagulation factor X0303
Chain A, probable fosfomycin resistance protein0011
Chain B, probable fosfomycin resistance protein0011
DNA polymerase catalytic subunit0101
DNA polymerase catalytic subunit0101
DNA polymerase alpha catalytic subunit0101
DNA polymerase delta catalytic subunit0101
ClpP2002
POU domain, class 2, transcription factor 20001
Transitional endoplasmic reticulum ATPase0101
Purine nucleoside phosphorylase0011
Chain A, DEOXYNUCLEOSIDE KINASE0101
Spike glycoprotein0033
Replicase polyprotein 1ab0134
Transmembrane protease serine 20033
Procathepsin L0033
Replicase polyprotein 1a0033
Replicase polyprotein 1ab0033
Replicase polyprotein 1ab0134
Replicase polyprotein 1ab0134
Equilibrative nucleoside transporter 10101
Glycine receptor subunit alpha-10022
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10101
Serine racemase0101
Olfactory receptor 51E20011
Sodium- and chloride-dependent glycine transporter 20101
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
Genome polyprotein 0101
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40303
Muscarinic acetylcholine receptor M50101
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Sigma intracellular receptor 20101
Cyclic GMP-AMP synthase0101
Toll-like receptor 90101
Toll-like receptor 70101
GALC protein1001
Prostacyclin receptor0123
Prostaglandin D2 receptor0022
Luciferase7007
DNA repair protein RAD52 homolog isoform a0001
Cytochrome P450 3A50203
Oxysterols receptor LXR-beta0101
Tyrosine-protein kinase JAK2 0011
Chain A, Cell Division Protein Kinase 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, Cell Division Protein Kinase 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, Cell Division Protein Kinase 20101
DNA repair and recombination protein RadA0011
Heat shock protein HSP 90-alpha0011
G2/mitotic-specific cyclin-B10303
Indoleamine 2,3-dioxygenase 10112
Cyclin-A20303
Nitric oxide synthase, brain0101
Cyclin-A10202
Chain A, Acetylcholinesterase0101
interferon gamma precursor0001
Solute carrier family 22 member 30101
Interstitial collagenase0101
Acetylcholinesterase0101
Acetylcholinesterase0404
Multidrug and toxin extrusion protein 20101
matrix metalloproteinase 1, partial0011
Parkin1001
pyruvate kinase1001
NPC intracellular cholesterol transporter 1 precursor2002
cytochrome P450 2C19 precursor2002
histone deacetylase 9 isoform 31001
ras-related protein Rab-9A1001
neuropeptide S receptor isoform A1001
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Integrin beta-33217
Integrin alpha-IIb3116
Amine oxidase [flavin-containing] A0101
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Cereblon isoform 40303
Bromodomain-containing protein 40101
DNA-binding protein Ikaros0014
DNA damage-binding protein 10213
Protein cereblon04310
Zinc finger protein Aiolos0011
Nuclear receptor coactivator 40101
MAP kinase-activated protein kinase 30022
atrial natriuretic peptide receptor 1 precursor1001
Alkaline phosphatase, tissue-nonspecific isozyme0202
Alkaline phosphatase, placental type0101
Alkaline phosphatase, tissue-nonspecific isozyme 0202
Intestinal-type alkaline phosphatase0101
Intestinal-type alkaline phosphatase0101
5'-nucleotidase0101
Phospholipase A-2-activating protein0101
CAAX prenyl protease 2 isoform 20001
streptokinase A precursor0011
Tubulin beta-4A chain0214
Tubulin beta chain0214
Tubulin alpha-3C chain0214
Tubulin alpha-1B chain0214
Tubulin alpha-4A chain0214
Tubulin beta-4B chain0214
Fatty-acid amide hydrolase 10303
DNA primase0101
Tubulin beta-3 chain0315
Tubulin beta-2A chain0214
Tubulin beta-8 chain0214
Tubulin alpha-3E chain0214
Tubulin alpha-1A chain0214
Tubulin alpha-1C chain0214
Tubulin beta-6 chain0214
Tubulin beta-2B chain0214
Tubulin beta-1 chain0214
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
5-hydroxytryptamine receptor 1A0101
Type-1 angiotensin II receptor0101
importin subunit beta-1 isoform 13003
snurportin-13003
Large neutral amino acids transporter small subunit 1 0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Thymidylate synthase 0202
Thymidylate synthase 0202
polyunsaturated fatty acid lipoxygenase ALOX121001
transcriptional regulator ERG isoform 31001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 11001
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0405
Dihydrofolate reductase0304
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0304
Thymidylate synthase0303
Bifunctional dihydrofolate reductase-thymidylate synthase0101
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0202
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0202
Dihydrofolate reductase0303
Histidine decarboxylase0112
Trifunctional purine biosynthetic protein adenosine-30303
Bifunctional purine biosynthesis protein ATIC0404
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0314
Mu-type opioid receptor0314
Kappa-type opioid receptor0314
Reduced folate transporter0303
6-phosphogluconate dehydrogenase, decarboxylating0101
Dihydrofolate reductase0101
Pteridine reductase 10101
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30202
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0304
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 11001
Serine racemase0101
Glucocorticoid receptor08316
Glycine receptor subunit alpha-10808
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
Nuclear receptor subfamily 1 group I member 20011
Translocator protein0202
UDP-glucuronosyltransferase 2B70305
UDP-glucuronosyltransferase 1A40203
UDP-glucuronosyltransferase 2B10 0202
Nuclear receptor corepressor 10101
Integrin beta-10202
Leukotriene A-4 hydrolase0101
Integrin alpha-40101
Nuclear receptor corepressor 20101
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
Glutamate receptor 10101
Glutamate receptor 30101
Glutamate receptor 40101
Inosine-5'-monophosphate dehydrogenase 1 0202
Peroxisome proliferator-activated receptor gamma0011
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A70001
UDP-glucuronosyltransferase 1A100001
UDP-glucuronosyltransferase 1A80001
Chain A, NAD-dependent deacetylase0101
Poly [ADP-ribose] polymerase 20101
NAD-dependent histone deacetylase SIR20101
Coagulation factor VII0101
Poly [ADP-ribose] polymerase 10101
Tissue factor0202
NAD-dependent protein deacetylase HST20101
Protein mono-ADP-ribosyltransferase PARP150101
NAD(+) hydrolase SARM10101
NAD-dependent protein deacetylase sirtuin-20202
NAD-dependent protein deacetylase sirtuin-60101
NAD-dependent protein deacetylase sirtuin-10101
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0202
NAD-dependent protein deacetylase 0101
Platelet-derived growth factor receptor beta0303
Platelet-derived growth factor receptor alpha 0202
Vascular endothelial growth factor receptor 20303
Cyclin-dependent kinase 100033
Platelet glycoprotein VI0011
Acetylcholinesterase0101
Kappa-type opioid receptor0011
Mu-type opioid receptor0224
Delta-type opioid receptor0314
Kappa-type opioid receptor0202
Kappa-type opioid receptor0112
Mu-type opioid receptor0112
Delta-type opioid receptor0112
Mu-type opioid receptor0202
Genome polyprotein 0101
Tubulin alpha-1A chain0012
Tubulin beta chain0011
Integrin alpha-V 0202
Botulinum neurotoxin type A 0101
Apoptosis regulator Bcl-20101
Substance-K receptor0202
Cholecystokinin receptor type A0202
Melanocortin receptor 50202
Bcl-2-like protein 10101
Beta-tubulin 0101
Chain B, Cell division protein kinase 60101
Chain B, Cell division protein kinase 60101
Cyclin-T10202
Cyclin-K0101
Acetylcholinesterase0101
G1/S-specific cyclin-D10303
G1/S-specific cyclin-E10101
G1/S-specific cyclin-D20101
G1/S-specific cyclin-D30202
Cyclin-H0202
CDK-activating kinase assembly factor MAT10101
Cyclin-dependent kinase 5 activator 10101
Myosin light chain kinase, smooth muscle0033
Tubulin alpha-1A chain0033
Receptor protein-tyrosine kinase 0101
Chain A, Thymidylate Synthase0101
Chain A, Thymidylate Synthase0101
Chain A, Thymidylate Synthase0101
Serine hydroxymethyltransferase, cytosolic0112
Thymidylate synthase 0101
Adenosine deaminase0101
Adenosine deaminase 0101
Proto-oncogene tyrosine-protein kinase Src0213
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0415
Progesterone receptor0416
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Androgen receptor0415
Glutamine synthetase0011
Histamine H1 receptor0022
Nociceptin receptor0011
Estrogen receptor beta0314
Receptor-type tyrosine-protein phosphatase beta0001
Low molecular weight phosphotyrosine protein phosphatase0101
P2X purinoceptor 10011
P2X purinoceptor 10101
P2X purinoceptor 40011
Trans-sialidase0101
Trans-sialidase0101
P2X purinoceptor 20011
Solute carrier family 22 member 10101
Solute carrier organic anion transporter family member 1A40202
Solute carrier family 22 member 20101
Albumin0044
Histidine-rich protein PFHRP-II0101
Cytochrome P450 2D10101
Cytochrome P450 2D260101
Cytochrome P450 2D30101
Solute carrier family 22 member 10203
Cytochrome P450 2D40101
Solute carrier family 22 member 20202
Bifunctional epoxide hydrolase 20303
Vascular endothelial growth factor receptor 30202
NS5 0011
Polymerase basic protein 20011
RNA-directed RNA polymerase catalytic subunit0011
Polymerase acidic protein0011
Adenosylhomocysteinase0002
Adenosine receptor A2a0101
Adenosine receptor A10101
Adenosine receptor A10101
Genome polyprotein0011
DNA-directed RNA polymerase subunit beta0101
Solute carrier organic anion transporter family member 2B1 0202
NH(3)-dependent NAD(+) synthetase0101
Arylacetamide deacetylase0102
Caspase-10101
Solute carrier organic anion transporter family member 1A20101
DNA-directed RNA polymerase subunit beta0101
Lanosterol 14-alpha demethylase0101
Chain A, Activated Factor Xa Heavy Chain0101
Coagulation factor XII0101
Suppressor of tumorigenicity 14 protein0101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Eukaryotic translation initiation factor 4E0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0426
Peptidyl-prolyl cis-trans isomerase FKBP1B0022
Peptidyl-prolyl cis-trans isomerase FKBP50202
Programmed cell death protein 40011
Serine/threonine-protein kinase mTOR 0101
Carbonic anhydrase0101
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
melanocortin receptor 40112
Tyrosine-protein kinase ABL10101
5-hydroxytryptamine receptor 1A0101
Aromatase0202
Cyclin-C0112
Serine/threonine-protein kinase B-raf 0101
5-hydroxytryptamine receptor 70101
5-hydroxytryptamine receptor 5A0101
DNA-dependent protein kinase catalytic subunit0202
Protein delta homolog 10123
Vascular endothelial growth factor receptor 20101
Poly [ADP-ribose] polymerase tankyrase-20022
RuvB-like 20112
RuvB-like 10101
Chain A, Mineralocorticoid receptor0101
Chain A, Mineralocorticoid receptor0101
Vpr1001
Mast/stem cell growth factor receptor Kit0101
Beta-adrenergic receptor kinase 10101
G protein-coupled receptor kinase 50101
Serine/threonine-protein kinase ULK30011
Bromodomain-containing protein 90011
Serine/threonine-protein kinase 30011
Bromodomain-containing protein 70011
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Splicing factor 3B subunit 30101
Prostaglandin G/H synthase 20101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
Integrin subunit alpha 2b0101
Integrin alpha-50101
Integrin beta-3 0101
Cocaine esterase0101
Cytochrome P450 2A60101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
Sigma non-opioid intracellular receptor 10101
Alpha-1D adrenergic receptor0101
D-alanyl-D-alanine dipeptidase0101
Thymidine kinase, cytosolic0001
Dipeptidyl peptidase 40101
Adenosylhomocysteinase0101
RNA-directed RNA polymerase 0112
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]