Sarcoma, Alveolar Soft Part

A variety of rare sarcoma having a reticulated fibrous stroma enclosing groups of sarcoma cells, which resemble epithelial cells and are enclosed in alveoli walled with connective tissue. It is a rare tumor, usually occurring between 15 and 35 years of age. It appears in the muscles of the extremities in adults and most commonly in the head and neck regions of children. Though slow-growing, it commonly metastasizes to the lungs, brain, bones, and lymph nodes. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1365)

Synonym
Sarcoma, Alveolar Soft Part

Excerpt	Reference
"Alveolar soft part sarcoma is a rare malignant tumor with unusual clinical behavior."	( Anderson, ME; Gebhardt, MC; Hornicek, FJ; Mankin, HJ; Raskin, KA, 2005)
"Alveolar soft part sarcoma is a rare malignancy usually considered resistant to conventional chemotherapy, but recent data suggest that the multikinase inhibitors sunitinib and cediranib could be active in this setting."	( Anract, P; Babinet, A; Blanchet, B; Boudou-Rouquette, P; Goldwasser, F; Larousserie, F; Mir, O, 2012)
"Alveolar soft part sarcomas are rarely seen and highly malignant tumors, and the prognosis of stage IV ASPS is poor."	( Yang, Y; Zhao, J, 2012)
"Alveolar soft part sarcoma is resistant to conventional cytotoxic chemotherapy."	( Blay, JY; Boye, K; Brahmi, M; Casali, PG; Duffaud, F; Fedenko, A; Gelderblom, H; Hindi, N; Italiano, A; Kawai, A; Kobayashi, E; Kosela, H; Le Cesne, A; Maki, RG; Martin-Broto, J; Mir, O; Patel, S; Provenzano, S; Rutkowski, P; Somaiah, N; Stacchiotti, S; Sundby Hall, K; Vincenzi, B, 2018)
"Alveolar Soft Part Sarcoma is a rare malignant tumor of uncertain histogenesis, representing 0."	( Garnica-Hayashi, L; Nava-Castañeda, Á; Rodríguez-Cabrera, L; Tovilla-Canales, JL; Zuazo, F, 2017)

Excerpt	Reference
"Treatment of alveolar soft part sarcoma has been difficult to evaluate because of the small numbers of cases seen, but it seemed that although treatment of the primary tumor in alveolar soft part sarcoma often is successful, treatment of metastatic tumors is unsuccessful."	( Anderson, ME; Gebhardt, MC; Hornicek, FJ; Mankin, HJ; Raskin, KA, 2005)
"Alveolar soft part sarcoma has a high metastasis rate but relatively good short-term survival."	( Agarwal, M; Ingle, A; Jambhekar, NA; Laskar, S; Puri, A; Rekhi, B, 2012)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	4 (5.00)	12.5806
2000's	15 (18.75)	18.1394
2010's	47 (58.75)	28.8240
2020's	14 (17.50)	9.53

Drug	Relationship Strength	Studies	Trials
salicylic acid	low	1	0
lactic acid	low	1	0
formaldehyde	low	1	0
celecoxib	low	1	0
pyrroles	low	7	0
quinazolines	medium	8	3
indazoles	medium	6	1
gadolinium	low	1	0
propiconazole	low	3	0
fluorodeoxyglucose f18	low	4	0
fingolimod hydrochloride	low	1	0
ecteinascidin 743	low	4	0
technetium tc 99m hydroxymethylene diphosphonate	low	1	0
dactinomycin	low	1	0
bromochloroacetic acid	low	1	0
dasatinib	medium	2	1
sphingosine	low	1	0
gadolinium dtpa	low	2	0
panobinostat	medium	1	1
arq 197	medium	2	2
crizotinib	medium	3	1
technetium tc 99m sestamibi	low	1	0
mesna	low	2	0
sodium pertechnetate tc 99m	low	1	0
cabozantinib	low	1	0
apatinib	low	2	0
transforming growth factor beta	medium	1	1
technetium tc 99m medronate	low	2	0

Protein Targets (906)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Vascular endothelial growth factor receptor 2	0	12	6	19
Bone morphogenetic protein receptor type-1B	0	0	8	8
Membrane-associated progesterone receptor component 1	0	0	6	6
Serine/threonine-protein kinase PLK4	0	3	8	11
ATP-dependent RNA helicase DDX3X	0	0	8	8
Pyridoxal kinase	0	0	8	8
Citron Rho-interacting kinase	0	0	8	8
Serine/threonine-protein kinase Chk1	0	1	8	9
Aurora kinase A	0	2	8	10
Cyclin-G-associated kinase	0	0	8	8
Ephrin type-B receptor 6	0	0	8	8
Peroxisomal acyl-coenzyme A oxidase 3	0	0	8	8
Receptor-interacting serine/threonine-protein kinase 2	0	2	8	10
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	8	8
Dynamin-like 120 kDa protein, mitochondrial	0	0	8	8
Eukaryotic translation initiation factor 5B	0	0	7	7
Rho-associated protein kinase 2	0	0	8	8
Serine/threonine-protein kinase ULK1	0	0	8	8
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	8	8
Ribosomal protein S6 kinase alpha-5	0	0	8	8
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	8	8
Ribosomal protein S6 kinase alpha-4	0	0	8	8
Serine/threonine-protein kinase 16	0	0	8	8
Serine/threonine-protein kinase 10	0	0	8	8
Serine/threonine-protein kinase D3	0	0	8	8
Structural maintenance of chromosomes protein 2	0	0	8	8
Mitogen-activated protein kinase kinase kinase 6	0	0	8	8
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	8	8
Serine/threonine-protein kinase LATS1	0	0	8	8
Serine/threonine-protein kinase PAK 4	0	2	8	10
Tyrosine-protein kinase ABL1	0	8	10	19
Epidermal growth factor receptor	0	5	8	13
High affinity nerve growth factor receptor	0	2	8	10
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	7	7
ADP/ATP translocase 2	0	0	8	8
Protein kinase C beta type	0	0	8	8
Insulin receptor	0	3	8	11
Tyrosine-protein kinase Lck	0	5	8	13
Tyrosine-protein kinase Fyn	0	3	8	11
Cyclin-dependent kinase 1	0	2	8	10
Glycogen phosphorylase, liver form	0	0	8	8
Tyrosine-protein kinase Fes/Fps	0	0	8	8
Adenine phosphoribosyltransferase	0	0	7	7
Tyrosine-protein kinase Yes	0	1	8	9
Tyrosine-protein kinase Lyn	0	1	8	9
Proto-oncogene tyrosine-protein kinase receptor Ret	0	5	8	13
Insulin-like growth factor 1 receptor	0	3	8	11
Signal recognition particle receptor subunit alpha	0	0	8	8
Cytochrome c1, heme protein, mitochondrial	0	0	8	8
Hepatocyte growth factor receptor	0	6	8	15
Tyrosine-protein kinase HCK	0	3	8	11
Platelet-derived growth factor receptor beta	0	8	8	16
Serine/threonine-protein kinase A-Raf	0	0	8	8
Glycogen phosphorylase, brain form	0	0	8	8
Breakpoint cluster region protein	0	3	10	14
Serine/threonine-protein kinase pim-1	0	0	8	8
Fibroblast growth factor receptor 1	0	7	8	15
DNA topoisomerase 2-alpha	0	0	6	6
Cyclin-dependent kinase 4	0	0	8	8
ADP/ATP translocase 3	0	0	8	8
Inosine-5'-monophosphate dehydrogenase 2	0	0	8	8
Proto-oncogene tyrosine-protein kinase Src	0	6	8	14
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	8	8
Serine/threonine-protein kinase B-raf	0	0	8	8
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	8	8
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	8	8
Tyrosine-protein kinase Fer	0	0	8	8
Protein kinase C alpha type	0	1	8	9
cAMP-dependent protein kinase catalytic subunit alpha	0	0	8	8
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	8	8
Casein kinase II subunit alpha'	0	0	8	8
Ras-related protein Rab-6A	0	0	7	7
Multifunctional protein ADE2	0	0	8	8
cAMP-dependent protein kinase catalytic subunit beta	0	0	8	8
Ferrochelatase, mitochondrial	0	0	8	8
Ribosomal protein S6 kinase beta-1	0	1	8	9
Tyrosine-protein kinase JAK1	0	1	8	9
Cyclin-dependent kinase 2	0	3	8	11
Beta-adrenergic receptor kinase 1	0	0	8	8
Probable ATP-dependent RNA helicase DDX6	0	0	8	8
Mitogen-activated protein kinase 3	0	0	8	8
MAP/microtubule affinity-regulating kinase 3	0	0	8	8
Deoxycytidine kinase	0	0	8	8
Mitogen-activated protein kinase 1	0	0	8	8
Ephrin type-A receptor 2	0	2	8	10
Ephrin type-B receptor 2	0	2	8	10
Non-receptor tyrosine-protein kinase TYK2	0	1	8	9
UMP-CMP kinase	0	0	7	7
Phosphatidylethanolamine-binding protein 1	0	0	8	8
Wee1-like protein kinase	0	0	8	8
Heme oxygenase 2	0	0	8	8
S-adenosylmethionine synthase isoform type-2	0	0	8	8
DnaJ homolog subfamily A member 1	0	0	8	8
RAC-alpha serine/threonine-protein kinase	0	3	8	11
RAC-beta serine/threonine-protein kinase	0	2	8	10
DNA replication licensing factor MCM4	0	0	8	8
Dual specificity mitogen-activated protein kinase kinase 2	0	1	8	9
Receptor-type tyrosine-protein kinase FLT3	0	4	8	13
Bone morphogenetic protein receptor type-1A	0	0	8	8
Activin receptor type-1B	0	0	8	8
TGF-beta receptor type-1	0	0	8	8
TGF-beta receptor type-2	0	0	8	8
Electron transfer flavoprotein subunit beta	0	0	7	7
Tyrosine-protein kinase CSK	0	1	8	9
Glycine--tRNA ligase	0	0	8	8
Protein kinase C iota type	0	0	8	8
Exosome RNA helicase MTR4	0	0	8	8
Tyrosine-protein kinase Tec	0	1	8	9
Tyrosine-protein kinase ABL2	0	0	8	8
Tyrosine-protein kinase FRK	0	0	8	8
G protein-coupled receptor kinase 6	0	0	7	7
Tyrosine-protein kinase SYK	0	1	8	9
26S proteasome regulatory subunit 6B	0	0	8	8
Mitogen-activated protein kinase 8	0	0	8	8
Mitogen-activated protein kinase 9	0	0	8	8
Dual specificity mitogen-activated protein kinase kinase 3	0	0	8	8
Casein kinase I isoform alpha	0	2	8	10
Casein kinase I isoform delta	0	0	8	8
MAP kinase-activated protein kinase 2	0	1	8	9
Elongation factor Tu, mitochondrial	0	0	8	8
Cysteine--tRNA ligase, cytoplasmic	0	0	8	8
Casein kinase I isoform epsilon	0	0	8	8
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	8	8
Dual specificity protein kinase CLK1	0	0	8	8
Dual specificity protein kinase CLK2	0	0	8	8
Dual specificity protein kinase CLK3	0	0	8	8
Glycogen synthase kinase-3 alpha	0	0	8	8
Glycogen synthase kinase-3 beta	0	0	8	8
Cyclin-dependent kinase 7	0	1	8	9
Cyclin-dependent kinase 9	0	0	8	8
Ras-related protein Rab-27A	0	0	8	8
Interleukin-1 receptor-associated kinase 1	0	0	8	8
Ribosomal protein S6 kinase alpha-3	0	2	8	10
Serine/threonine-protein kinase Nek2	0	1	8	9
Serine/threonine-protein kinase Nek3	0	0	8	8
Dual specificity mitogen-activated protein kinase kinase 6	0	0	8	8
LIM domain kinase 1	0	1	8	9
LIM domain kinase 2	0	1	8	9
Mitogen-activated protein kinase 10	0	0	8	8
Tyrosine--tRNA ligase, cytoplasmic	0	0	8	8
5'-AMP-activated protein kinase subunit gamma-1	0	0	8	9
Ephrin type-B receptor 3	0	0	8	8
Ephrin type-A receptor 5	0	0	8	8
Ephrin type-B receptor 4	0	3	8	11
Ephrin type-A receptor 4	0	0	8	8
Adenylate kinase 2, mitochondrial	0	0	8	8
Adenosine kinase	0	0	8	8
Ras-related protein Rab-10	0	0	8	8
Actin-related protein 3	0	0	8	8
Actin-related protein 2	0	0	8	8
GTP-binding nuclear protein Ran	0	0	8	8
Cyclin-dependent kinase 3	0	0	8	8
Cyclin-dependent kinase 6	0	0	8	8
Cyclin-dependent-like kinase 5	0	0	8	8
Cyclin-dependent kinase 16	0	0	8	8
Cyclin-dependent kinase 17	0	0	8	8
ATP-dependent 6-phosphofructokinase, platelet type	0	0	8	8
Dual specificity mitogen-activated protein kinase kinase 1	0	1	8	9
DNA topoisomerase 2-beta	0	0	8	8
Protein kinase C theta type	0	0	8	8
Activin receptor type-1	0	0	8	8
Macrophage-stimulating protein receptor	0	2	8	10
Focal adhesion kinase 1	0	2	8	10
Protein kinase C zeta type	0	1	6	7
Protein kinase C delta type	0	1	8	9
Tyrosine-protein kinase BTK	0	3	8	11
Activated CDC42 kinase 1	0	1	8	9
Epithelial discoidin domain-containing receptor 1	0	3	8	11
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	8	8
Serine/threonine-protein kinase 4	0	0	8	8
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	1	8	10
Dual specificity mitogen-activated protein kinase kinase 5	0	0	8	8
Mitogen-activated protein kinase 7	0	0	8	8
Serine/threonine-protein kinase PAK 2	0	0	8	8
Serine/threonine-protein kinase 3	0	0	8	8
Mitogen-activated protein kinase kinase kinase 1	0	0	8	8
Integrin-linked protein kinase	0	0	8	8
Rho-associated protein kinase 1	0	0	8	8
Non-receptor tyrosine-protein kinase TNK1	0	0	8	8
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	8	8
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	8	8
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	8	8
Activin receptor type-2B	0	0	8	8
Bone morphogenetic protein receptor type-2	0	0	8	8
Protein-tyrosine kinase 6	0	1	8	9
cGMP-dependent protein kinase 1	0	0	8	8
Cyclin-dependent kinase 13	0	0	8	8
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	8	8
Protein-tyrosine kinase 2-beta	0	0	8	8
Maternal embryonic leucine zipper kinase	0	0	8	8
Structural maintenance of chromosomes protein 1A	0	0	8	8
Chromodomain-helicase-DNA-binding protein 4	0	0	8	8
Delta(24)-sterol reductase	0	0	8	8
Ribosomal protein S6 kinase alpha-1	0	2	8	10
Dual specificity testis-specific protein kinase 1	0	0	7	7
Myosin light chain kinase, smooth muscle	0	0	8	8
Mitogen-activated protein kinase 11	0	1	8	9
Serine/threonine-protein kinase STK11	0	0	8	8
Serine/threonine-protein kinase N1	0	0	8	8
Serine/threonine-protein kinase N2	0	1	8	9
Mitogen-activated protein kinase 14	0	3	9	12
Calcium/calmodulin-dependent protein kinase type IV	0	0	8	8
Mitogen-activated protein kinase kinase kinase 11	0	0	8	8
MAP kinase-activated protein kinase 3	0	0	1	1
Discoidin domain-containing receptor 2	0	4	8	12
AP2-associated protein kinase 1	0	1	8	9
Myosin light chain kinase 3	0	0	8	8
Uncharacterized aarF domain-containing protein kinase 5	0	0	5	5
Putative heat shock protein HSP 90-beta 2	0	0	8	8
Rab-like protein 3	0	0	5	5
Serine/threonine-protein kinase MRCK alpha	0	0	8	8
Serine/threonine-protein kinase MRCK gamma	0	0	8	8
Acyl-CoA dehydrogenase family member 10	0	0	7	7
Serine/threonine-protein kinase ULK3	0	0	8	8
Uncharacterized protein FLJ45252	0	0	8	8
Acyl-CoA dehydrogenase family member 11	0	0	8	8
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	8	8
Serine/threonine-protein kinase MARK2	0	0	8	8
Serine/threonine-protein kinase TAO1	0	0	8	8
STE20-related kinase adapter protein alpha	0	0	8	8
Myosin-14	0	0	8	8
AarF domain-containing protein kinase 1	0	0	8	8
ATP-dependent RNA helicase DDX42	0	0	8	8
Mitogen-activated protein kinase kinase kinase kinase 3	0	1	8	9
MAP kinase-activated protein kinase 5	0	0	8	8
Atypical kinase COQ8A, mitochondrial	0	0	8	8
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	8	8
Mitogen-activated protein kinase 15	0	0	8	8
Serine/threonine-protein kinase Nek9	0	0	8	8
Serine/threonine-protein kinase Nek7	0	0	8	8
ATP-dependent RNA helicase DDX1	0	0	8	8
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	8	8
Aurora kinase B	0	2	8	10
MAP/microtubule affinity-regulating kinase 4	0	0	8	8
Serine/threonine-protein kinase Nek1	0	0	8	8
PAS domain-containing serine/threonine-protein kinase	0	0	6	6
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	8	8
EKC/KEOPS complex subunit TP53RK	0	0	8	8
Dual specificity testis-specific protein kinase 2	0	0	4	4
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	2	8	10
Mitogen-activated protein kinase kinase kinase 5	0	0	8	8
Mitogen-activated protein kinase kinase kinase 3	0	0	8	8
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	8	8
Nucleolar GTP-binding protein 1	0	0	8	8
Serine/threonine-protein kinase D2	0	0	8	8
RNA cytidine acetyltransferase	0	0	8	8
Serine/threonine-protein kinase SIK2	0	1	8	9
STE20-like serine/threonine-protein kinase	0	0	8	8
Serine/threonine-protein kinase TAO3	0	0	8	8
dCTP pyrophosphatase 1	0	0	8	8
Dual specificity protein kinase CLK4	0	0	8	8
Casein kinase I isoform gamma-1	0	0	8	8
Serine/threonine-protein kinase PAK 6	0	1	8	9
Phenylalanine--tRNA ligase beta subunit	0	0	8	8
BMP-2-inducible protein kinase	0	0	8	8
Obg-like ATPase 1	0	0	8	8
Midasin	0	0	8	8
Interleukin-1 receptor-associated kinase 4	0	0	8	8
Mitogen-activated protein kinase kinase kinase 20	0	0	8	8
Cyclin-dependent kinase 12	0	0	8	8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	8	8
Serine/threonine-protein kinase pim-2	0	0	7	7
Serine/threonine-protein kinase 26	0	0	8	8
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	8	8
Serine/threonine-protein kinase NLK	0	0	8	8
5'-AMP-activated protein kinase subunit gamma-2	0	0	8	9
Serine/threonine-protein kinase TBK1	0	2	8	10
Septin-9	0	0	8	8
Ribosomal protein S6 kinase alpha-6	0	0	8	8
TRAF2 and NCK-interacting protein kinase	0	0	8	8
Serine/threonine-protein kinase TAO2	0	0	8	8
Long-chain-fatty-acid--CoA ligase 5	0	0	8	8
Serine/threonine-protein kinase ICK	0	0	8	8
RAC-gamma serine/threonine-protein kinase	0	1	8	9
Serine/threonine-protein kinase 38-like	0	0	7	7
Serine/threonine-protein kinase SIK3	0	1	8	9
Mitogen-activated protein kinase kinase kinase 2	0	0	8	8
Thyroid hormone receptor-associated protein 3	0	0	6	6
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	8	8
Receptor-interacting serine/threonine-protein kinase 3	0	0	8	8
Serine/threonine-protein kinase MRCK beta	0	0	8	8
Interleukin-1 receptor-associated kinase 3	0	0	8	8
Casein kinase I isoform gamma-3	0	0	8	8
Mitogen-activated protein kinase kinase kinase 4	0	0	8	8
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Leukotriene C4 synthase	0	0	6	6
Luciferase	4	0	0	4
acetylcholinesterase	5	0	0	5
RAR-related orphan receptor gamma	11	0	0	11
SMAD family member 2	3	0	0	3
PPM1D protein	10	0	0	10
SMAD family member 3	3	0	0	3
TDP1 protein	9	0	0	9
GLI family zinc finger 3	8	0	0	8
AR protein	11	0	0	11
caspase 7, apoptosis-related cysteine protease	4	0	0	4
estrogen receptor 2 (ER beta)	8	0	0	8
nuclear receptor subfamily 1, group I, member 3	6	0	0	6
progesterone receptor	7	0	0	7
cytochrome P450 family 3 subfamily A polypeptide 4	9	0	0	9
retinoic acid nuclear receptor alpha variant 1	8	0	0	8
retinoid X nuclear receptor alpha	7	0	0	7
estrogen-related nuclear receptor alpha	9	0	0	9
farnesoid X nuclear receptor	6	0	0	6
pregnane X nuclear receptor	7	0	0	7
estrogen nuclear receptor alpha	11	0	0	11
G	7	0	0	7
cytochrome P450 2D6	8	0	0	8
peroxisome proliferator-activated receptor delta	7	0	0	7
peroxisome proliferator activated receptor gamma	8	0	0	8
vitamin D (1,25- dihydroxyvitamin D3) receptor	4	0	0	4
caspase-3	4	0	0	4
aryl hydrocarbon receptor	6	0	0	6
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	7	0	0	7
Histone H2A.x	4	0	0	4
thyroid hormone receptor beta isoform 2	8	0	0	8
histone deacetylase 9 isoform 3	1	0	0	1
tyrosine-protein kinase Yes	7	0	0	7
nuclear factor erythroid 2-related factor 2 isoform 1	8	0	0	8
Cell division cycle 7-related protein kinase	0	0	5	5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	3	6	9
Serine/threonine-protein kinase 25	0	0	6	6
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	6	6
Serine/threonine-protein kinase RIO3	0	0	6	6
Dual specificity mitogen-activated protein kinase kinase 7	0	0	6	6
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	1	6	8
Peripheral plasma membrane protein CASK	0	0	6	6
Serine/threonine-protein kinase DCLK1	0	0	6	6
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	1	6	7
Muscle, skeletal receptor tyrosine-protein kinase	0	0	6	6
Mitogen-activated protein kinase 13	0	1	6	7
3-phosphoinositide-dependent protein kinase 1	0	1	6	7
Mitogen-activated protein kinase kinase kinase 13	0	0	6	6
Death-associated protein kinase 3	0	0	6	6
Mitogen-activated protein kinase kinase kinase 7	0	0	6	6
NUAK family SNF1-like kinase 1	0	1	6	7
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	6	6
Tyrosine-protein kinase JAK2	0	1	7	8
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	6	6
Serine/threonine-protein kinase PAK 3	0	0	6	6
Cyclin-dependent kinase-like 5	0	0	6	6
Voltage-dependent calcium channel gamma-2 subunit	6	0	0	6
Serine/threonine-protein kinase 17B	0	0	6	6
Cyclin-dependent kinase 14	0	0	6	6
Serine/threonine-protein kinase OSR1	0	0	6	6
Serine/threonine-protein kinase Chk2	0	1	6	7
Interferon beta	12	0	0	12
HLA class I histocompatibility antigen, B alpha chain	7	0	0	7
RAF proto-oncogene serine/threonine-protein kinase	0	2	6	8
Receptor tyrosine-protein kinase erbB-2	0	2	6	8
Cellular tumor antigen p53	8	0	0	8
Macrophage colony-stimulating factor 1 receptor	0	5	6	11
Cytochrome P450 3A4	0	4	0	4
Proto-oncogene tyrosine-protein kinase ROS	0	2	6	8
Tyrosine-protein kinase Fgr	0	1	6	7
Wee1-like protein kinase 2	0	0	6	6
Uncharacterized serine/threonine-protein kinase SBK3	0	0	6	6
Cytochrome P450 2D6	0	3	1	4
Mast/stem cell growth factor receptor Kit	0	7	6	13
Insulin receptor-related protein	0	0	6	6
Platelet-derived growth factor receptor alpha	0	8	6	14
Vascular endothelial growth factor receptor 1	0	7	6	13
Glutamate receptor 2	6	0	0	6
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	6	6
Serine/threonine-protein kinase MAK	0	0	6	6
Cyclin-dependent kinase 11B	0	0	6	6
Ephrin type-A receptor 1	0	0	6	6
Fibroblast growth factor receptor 2	0	1	6	7
Receptor tyrosine-protein kinase erbB-3	0	0	6	6
Fibroblast growth factor receptor 4	0	0	6	6
Fibroblast growth factor receptor 3	0	1	6	7
cAMP-dependent protein kinase catalytic subunit gamma	0	0	6	6
Protein kinase C eta type	0	0	6	6
Activin receptor type-2A	0	0	6	6
Ephrin type-A receptor 3	0	0	6	6
Ephrin type-A receptor 8	0	0	6	6
Leukocyte tyrosine kinase receptor	0	0	6	6
Tyrosine-protein kinase receptor UFO	0	3	6	9
Mitogen-activated protein kinase 4	0	0	6	6
G protein-coupled receptor kinase 4	0	0	6	6
Dual specificity protein kinase TTK	0	0	7	7
Prostaglandin G/H synthase 2	0	3	7	11
Myosin-10	0	0	5	5
Tyrosine-protein kinase receptor Tie-1	0	0	6	6
Vascular endothelial growth factor receptor 3	0	6	6	12
Serine/threonine-protein kinase receptor R3	0	0	6	6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	2	6	8
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	3	6	9
Serine/threonine-protein kinase mTOR	0	2	6	8
Megakaryocyte-associated tyrosine-protein kinase	0	0	6	6
Tyrosine-protein kinase TXK	0	1	6	7
Tyrosine-protein kinase ZAP-70	0	0	6	6
Dual specificity mitogen-activated protein kinase kinase 4	0	0	6	6
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	6	6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	3	6	9
Cyclin-dependent kinase 8	0	0	6	6
Choline-phosphate cytidylyltransferase A	0	0	5	5
Tyrosine-protein kinase Blk	0	1	6	7
Cytoplasmic tyrosine-protein kinase BMX	0	1	6	7
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	6	6
Serine/threonine-protein kinase Nek4	0	0	6	6
Tyrosine-protein kinase JAK3	0	1	6	7
Serine/threonine-protein kinase PLK1	0	4	7	11
Death-associated protein kinase 1	0	0	6	6
Mitogen-activated protein kinase 12	0	1	6	7
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	1	6	8
Ephrin type-B receptor 1	0	0	6	6
Hormonally up-regulated neu tumor-associated kinase	0	0	6	6
Serine/threonine-protein kinase SIK1	0	2	6	8
Receptor-interacting serine/threonine-protein kinase 4	0	0	6	6
Spike glycoprotein	5	0	1	6
Cell division control protein 2 homolog	0	0	6	6
Calcium-dependent protein kinase 1	0	0	6	6
Casein kinase II subunit alpha	0	0	6	6
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	6	6
SRSF protein kinase 2	0	0	6	6
Casein kinase I isoform gamma-2	0	0	7	7
Mitogen-activated protein kinase kinase kinase 9	0	0	6	6
Serine/threonine-protein kinase PknB	0	0	6	6
Cyclin-dependent kinase-like 1	0	0	6	6
Protein kinase C epsilon type	0	0	6	6
Angiopoietin-1 receptor	0	3	6	9
Mitogen-activated protein kinase kinase kinase 10	0	0	6	6
Tyrosine-protein kinase receptor TYRO3	0	1	6	7
Cyclin-dependent kinase 18	0	0	6	6
Tyrosine-protein kinase ITK/TSK	0	1	6	7
Myotonin-protein kinase	0	0	6	6
Mitogen-activated protein kinase kinase kinase 12	0	0	6	6
Tyrosine-protein kinase Mer	0	1	6	7
Serine/threonine-protein kinase PAK 1	0	0	6	6
cGMP-dependent protein kinase 2	0	0	6	6
Serine/threonine-protein kinase PRP4 homolog	0	0	6	6
Receptor-interacting serine/threonine-protein kinase 1	0	1	6	7
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	6	6
Calcium/calmodulin-dependent protein kinase type 1	0	0	6	6
Peroxisomal acyl-coenzyme A oxidase 1	0	0	7	7
Serine/threonine-protein kinase D1	0	1	6	7
Serine/threonine-protein kinase 38	0	0	6	6
Receptor tyrosine-protein kinase erbB-4	0	0	6	6
Ribosomal protein S6 kinase alpha-2	0	0	6	6
Ephrin type-A receptor 7	0	0	7	7
Rhodopsin kinase GRK1	0	0	6	6
NT-3 growth factor receptor	0	0	6	6
BDNF/NT-3 growth factors receptor	0	1	6	7
Mitogen-activated protein kinase 6	0	0	6	6
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	6	6
Serine/threonine-protein kinase SBK1	0	0	6	6
Mitogen-activated protein kinase kinase kinase 19	0	0	6	6
Serine/threonine-protein kinase TNNI3K	0	0	6	6
Leucine-rich repeat serine/threonine-protein kinase 2	0	1	6	7
Serine/threonine-protein kinase Nek5	0	0	6	6
Serine/threonine-protein kinase N3	0	0	6	6
Dual serine/threonine and tyrosine protein kinase	0	0	6	6
Mitogen-activated protein kinase kinase kinase 15	0	0	6	6
ATP-dependent RNA helicase DHX30	0	0	6	6
Serine/threonine-protein kinase tousled-like 2	0	0	6	6
Serine/threonine-protein kinase 32C	0	0	6	6
Serine/threonine-protein kinase pim-3	0	0	6	6
Serine/threonine-protein kinase VRK2	0	0	6	6
Myosin light chain kinase family member 4	0	0	6	6
Homeodomain-interacting protein kinase 1	0	0	6	6
Calcium/calmodulin-dependent protein kinase type 1D	0	0	6	6
Cyclin-dependent kinase-like 3	0	0	6	6
Serine/threonine-protein kinase BRSK2	0	0	6	6
Serine/threonine-protein kinase NIM1	0	0	6	6
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	3	3
Serine/threonine-protein kinase ULK2	0	0	6	6
Misshapen-like kinase 1	0	0	6	6
Serine/threonine-protein kinase DCLK2	0	0	6	6
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	6	6
Casein kinase I isoform alpha-like	0	0	6	6
Homeodomain-interacting protein kinase 4	0	0	6	6
Myosin-IIIa	0	0	6	6
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	6	6
Serine/threonine-protein kinase Nek11	0	0	6	6
Serine/threonine-protein kinase BRSK1	0	0	6	6
Serine/threonine-protein kinase 35	0	0	6	6
Rhodopsin kinase GRK7	0	0	6	6
Serine/threonine-protein kinase 32A	0	0	6	6
Myosin-IIIb	0	0	6	6
Inositol hexakisphosphate kinase 1	7	0	0	7
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	6	6
Cyclin-dependent kinase-like 2	0	0	6	6
Serine/threonine-protein kinase Sgk3	0	0	6	6
Atypical kinase COQ8B, mitochondrial	0	0	6	6
Calcium/calmodulin-dependent protein kinase type 1G	0	0	6	6
Cyclin-dependent kinase 15	0	0	6	6
ATPase family AAA domain-containing protein 5	7	0	0	7
SRSF protein kinase 1	0	0	6	6
Ataxin-2	7	0	0	7
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	6	6
Serine/threonine-protein kinase RIO1	0	0	6	6
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	6	6
Serine/threonine-protein kinase RIO2	0	0	6	6
Cyclin-dependent kinase 19	0	0	6	6
Transient receptor potential cation channel subfamily M member 6	0	0	6	6
Testis-specific serine/threonine-protein kinase 1	0	0	6	6
Serine/threonine-protein kinase 33	0	0	6	6
Serine/threonine-protein kinase DCLK3	0	0	6	6
NUAK family SNF1-like kinase 2	0	0	7	7
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	6	6
Homeodomain-interacting protein kinase 2	0	0	6	6
Tyrosine-protein kinase Srms	0	0	6	6
Homeodomain-interacting protein kinase 3	0	0	6	6
Serine/threonine-protein kinase PLK3	0	3	6	9
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	6	6
Serine/threonine-protein kinase Nek6	0	0	6	6
SNF-related serine/threonine-protein kinase	0	0	6	6
Serine/threonine-protein kinase LATS2	0	0	6	6
Serine/threonine-protein kinase 36	0	0	6	6
Serine/threonine-protein kinase 32B	0	0	6	6
Serine/threonine-protein kinase PLK2	0	3	6	9
Serine/threonine-protein kinase MARK1	0	0	6	6
Serine/threonine-protein kinase PAK 5	0	1	6	7
eIF-2-alpha kinase GCN2	0	0	6	6
Phosphatidylinositol 4-kinase beta	0	0	6	6
Serine/threonine-protein kinase 17A	0	0	6	6
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	6	6
Ephrin type-A receptor 6	0	0	6	6
Death-associated protein kinase 2	0	0	6	6
Serine/threonine-protein kinase tousled-like 1	0	0	6	6
ALK tyrosine kinase receptor	0	4	8	12
SRSF protein kinase 3	0	0	6	6
Cyclin-dependent kinase 11A	0	0	6	6
Aurora kinase C	0	0	6	6
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	6	6
Microtubule-associated serine/threonine-protein kinase 1	0	0	6	6
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	7	7
Serine/threonine-protein kinase 24	0	0	7	7
cytochrome P450 2C9, partial	7	0	0	7
aldehyde dehydrogenase 1 family, member A1	4	0	0	4
thyroid stimulating hormone receptor	5	0	0	5
Nuclear receptor ROR-gamma	3	0	0	3
Fumarate hydratase	4	0	0	4
EWS/FLI fusion protein	8	0	0	8
polyprotein	4	0	0	4
Acyl-CoA desaturase 1	0	1	0	1
Kinesin-1 heavy chain	0	2	0	2
Potassium voltage-gated channel subfamily H member 2	0	3	0	3
Coiled-coil domain-containing protein 6	0	2	0	2
Isoleucine--tRNA ligase, mitochondrial	0	0	6	6
SAFB-like transcription modulator	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	2	0	0	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	1	0	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
phosphopantetheinyl transferase	3	0	0	3
euchromatic histone-lysine N-methyltransferase 2	3	0	0	3
vitamin D3 receptor isoform VDRA	4	0	0	4
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
DNA polymerase kappa isoform 1	2	0	0	2
histone acetyltransferase KAT2A isoform 1	2	0	0	2
ATP-dependent phosphofructokinase	2	0	0	2
Serine/threonine-protein kinase ATR	0	0	2	2
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Cruzipain	3	0	0	3
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
glp-1 receptor, partial	2	0	0	2
pregnane X receptor	2	0	0	2
hypoxia-inducible factor 1 alpha subunit	3	0	0	3
USP1 protein, partial	4	0	0	4
Smad3	2	0	0	2
thyroid stimulating hormone receptor	2	0	0	2
glucocorticoid receptor [Homo sapiens]	7	0	0	7
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
67.9K protein	2	0	0	2
Carbonic anhydrase	0	1	0	1
Rac1 protein	0	0	1	1
IDH1	2	0	0	2
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
activating transcription factor 6	3	0	0	3
thyrotropin-releasing hormone receptor	1	0	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	1	0	0	1
v-jun sarcoma virus 17 oncogene homolog (avian)	3	0	0	3
Caspase-7	2	0	0	2
interferon gamma precursor	0	0	0	1
prostaglandin E2 receptor EP2 subtype	0	0	0	1
thyroid hormone receptor beta isoform a	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 2	1	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	2	0	0	2
caspase-3	2	0	0	2
heat shock protein beta-1	1	0	0	1
geminin	5	0	0	5
peripheral myelin protein 22	4	0	0	4
cytochrome P450 3A4 isoform 1	2	0	0	2
lamin isoform A-delta10	5	0	0	5
Gamma-aminobutyric acid receptor subunit pi	2	0	0	2
Prostaglandin E synthase	0	1	0	1
Histone deacetylase 3	0	3	1	4
ATP-binding cassette sub-family C member 3	0	6	0	6
Multidrug resistance-associated protein 4	0	6	0	6
Carbonic anhydrase 12	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Cytochrome c oxidase subunit 1	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Bile salt export pump	0	8	0	8
Cytochrome c oxidase subunit 2	0	1	0	1
Carbonic anhydrase 1	0	4	0	4
Carbonic anhydrase 2	0	4	0	4
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 3	0	2	0	2
Procathepsin L	0	1	1	2
Aldo-keto reductase family 1 member B1	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Quinolone resistance protein NorA	0	2	0	2
Adenosine receptor A3	0	2	0	2
Cytochrome P450 2C9	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Beta-3 adrenergic receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	2	0	0	2
Alpha-1B adrenergic receptor	0	2	0	2
Calpain-2 catalytic subunit	0	1	0	1
Alpha-2B adrenergic receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	2	0	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	2	0	0	2
5-hydroxytryptamine receptor 1A	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	2	0	0	2
D(1A) dopamine receptor	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 4	0	2	0	2
Prostaglandin G/H synthase 1	0	2	0	3
Carbonic anhydrase 6	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	2	0	0	2
Sodium-dependent noradrenaline transporter	0	2	0	2
Adenosine receptor A1	0	1	0	1
Cruzipain	0	1	0	1
Sodium/hydrogen exchanger 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	2	0	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	2	0	0	2
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	2	0	0	2
Sodium-dependent serotonin transporter	0	2	0	2
Sodium-dependent serotonin transporter	0	0	1	1
Delta-type opioid receptor	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Bifunctional epoxide hydrolase 2	0	2	0	2
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Carbonic anhydrase	0	1	0	1
Alpha-1A adrenergic receptor	0	2	0	2
Carbonic anhydrase 7	0	2	0	2
Urotensin-2 receptor	0	1	0	1
Carbonic anhydrase	0	1	0	1
Histone deacetylase 4	0	3	0	3
Ras-related protein Rab-2A	0	0	1	1
D(2) dopamine receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	2	1	0	3
Gamma-aminobutyric acid receptor subunit beta-3	2	0	0	2
Gamma-aminobutyric acid receptor subunit beta-2	2	0	0	2
Prostaglandin G/H synthase 2	0	2	0	2
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	3	0	3
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Histone deacetylase 1	0	3	1	4
Carbonic anhydrase 9	0	4	0	4
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Delta carbonic anhydrase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Histone deacetylase 7	0	3	0	3
Rap guanine nucleotide exchange factor 4	1	0	0	1
GABA theta subunit	2	0	0	2
Histone deacetylase 2	0	3	1	4
Canalicular multispecific organic anion transporter 1	0	6	0	6
Carbonic anhydrase 4	0	2	0	2
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	3	0	3
Carbonic anhydrase 15	0	2	0	2
Histone deacetylase 8	0	3	0	3
P2Y purinoceptor 12	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	2	0	0	2
Histone deacetylase 6	0	3	1	4
Histone deacetylase 9	0	3	0	3
Carbonic anhydrase 14	0	2	0	2
Histone deacetylase 5	0	3	0	3
Carbonic anhydrase 5B, mitochondrial	0	2	0	2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2	0	1	0	1
Sodium-dependent phosphate transport protein 2B	0	1	0	1
Tyrosine-protein kinase ABL1	0	2	0	2
HLA class II histocompatibility antigen gamma chain	0	1	0	1
Nucleophosmin	0	1	0	1
Androgen receptor	0	1	0	1
G2/mitotic-specific cyclin-B1	0	2	0	2
ALK tyrosine kinase receptor	0	1	0	1
Angiopoietin-1 receptor	0	1	0	1
Lysine--tRNA ligase	0	1	0	1
Cyclin-dependent kinase 10	0	0	2	2
Macrophage-stimulating protein receptor	0	1	0	1
Mixed lineage kinase domain-like protein	0	0	1	1
Echinoderm microtubule-associated protein-like 4	0	1	0	1
Aurora kinase A-interacting protein	0	1	0	1
Chain A, 2-oxoglutarate Oxygenase	3	0	0	3
interleukin 8	2	0	0	2
survival motor neuron protein isoform d	3	0	0	3
Matrix metalloproteinase-9	0	1	0	1
Inositol monophosphatase 1	1	0	0	1
Isocitrate lyase	0	1	0	1
Chain A, HADH2 protein	1	0	0	1
Chain B, HADH2 protein	1	0	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
Chain A, Ferritin light chain	3	0	0	3
15-lipoxygenase, partial	2	0	0	2
Microtubule-associated protein tau	3	0	0	3
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	1	0	0	1
RAD51	0	1	0	1
Bloom syndrome protein isoform 1	2	0	0	2
huntingtin isoform 2	3	0	0	3
nuclear receptor ROR-gamma isoform 1	2	0	0	2
caspase-1 isoform alpha precursor	1	0	0	1
ATP-dependent translocase ABCB1	0	0	0	1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Caspase-7	1	0	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Reverse transcriptase/RNaseH	0	1	0	1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
GALC protein	2	0	0	2
GLS protein	2	0	0	2
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
Transmembrane protease serine 2	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
Proto-oncogene tyrosine-protein kinase Src	0	2	1	3
Transthyretin	0	0	1	1
Cytochrome P450 1A2	0	1	0	1
Neuronal proto-oncogene tyrosine-protein kinase Src	0	0	0	1
Proto-oncogene tyrosine-protein kinase LCK	0	2	0	2
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Cytochrome P450 2A6	0	1	0	1
Myosin light chain kinase, smooth muscle	0	0	3	3
Angiotensin-converting enzyme	0	1	0	1
Potassium voltage-gated channel subfamily E member 1	0	2	0	2
Tyrosine-protein kinase Blk	0	1	0	1
Cytochrome P450 2B6	0	1	0	1
Cytochrome P450 2C19	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	2	0	2
Tubulin alpha-1A chain	0	0	3	3
DNA-dependent protein kinase catalytic subunit	0	2	0	2
Myelin transcription factor 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Sodium channel protein type 5 subunit alpha	0	2	0	2
Breakpoint cluster region protein	0	1	0	1
Protein cereblon	0	0	1	2
Angiotensin-converting enzyme 2	0	0	1	1
Potassium voltage-gated channel subfamily D member 3	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	2
NF-kappa-B essential modulator	0	1	0	1
Sphingosine 1-phosphate receptor 1	0	0	1	1
RCG53912, isoform CRA_a	0	0	0	1
Sphingosine kinase 1	0	0	0	1
Sphingosine kinase 2	0	1	0	2
Sphingosine kinase 1	0	1	0	2
Chain A, Beta-lactamase	2	0	0	2
chromobox protein homolog 1	2	0	0	2
Serum paraoxonase/arylesterase 1	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
DNA repair and recombination protein RadA	0	0	1	1
Heat shock protein HSP 90-alpha	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	0	1	1
Cyclin-A2	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
Cyclin-A1	0	1	0	1
cellular tumor antigen p53 isoform a	1	0	0	1
Integrin beta-3	1	0	0	1
Integrin alpha-IIb	1	0	0	1
Histone deacetylase 8	0	1	0	1
Bromodomain-containing protein 4	0	1	0	1
Protein Tat	0	0	1	1
Leukotriene A-4 hydrolase	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	3	0	3
NAD-dependent protein deacetylase sirtuin-1	0	2	0	2
NAD-dependent protein deacetylase sirtuin-7	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	2	0	2
Histone deacetylase	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Acetylcholinesterase	0	3	0	3
Receptor protein-tyrosine kinase	0	1	0	1
nonstructural protein 1	1	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
DNA polymerase iota isoform a (long)	2	0	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Histamine H2 receptor	1	0	0	1
Guanine nucleotide-binding protein G	1	0	0	1
TAR DNA-binding protein 43	1	0	0	1
heat shock protein 90, putative	0	0	0	1
thioredoxin reductase	1	0	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	1	0	0	1
Estrogen receptor beta	0	0	0	1
Solute carrier family 22 member 6	0	1	0	1
Polyphenol oxidase 2	0	1	0	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Bile salt export pump	0	1	0	1
Albumin	0	1	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
acid sphingomyelinase	1	0	0	1
endonuclease IV	1	0	0	1
ATAD5 protein, partial	1	0	0	1
apical membrane antigen 1, AMA1	1	0	0	1
glucocerebrosidase	1	0	0	1
alpha-galactosidase	1	0	0	1
C-X-C chemokine receptor type 5 isoform 1	0	1	0	1
DNA polymerase beta	1	0	0	1
mitogen-activated protein kinase 1	1	0	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
C-C chemokine receptor type 6	0	1	0	1
apelin receptor	0	1	0	1
DNA polymerase eta isoform 1	1	0	0	1
bcl-2-related protein A1	0	1	0	1
streptokinase A precursor	0	0	1	1
Endoglycoceramidase II	0	0	0	1
Protein kinase C alpha type	0	1	0	1
Estrogen receptor	0	0	1	1
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Estrogen receptor beta	0	0	1	1
Protein kinase C eta type	0	1	0	1
Protein kinase C theta type	0	1	0	1
Solute carrier family 22 member 1	0	1	0	1
Mast/stem cell growth factor receptor Kit	0	1	0	1
Platelet-derived growth factor receptor beta	0	1	0	1
Aromatase	0	1	0	1
Translocator protein	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	0	1
Platelet-derived growth factor receptor alpha	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
Protein delta homolog 1	0	1	1	2
Serine/threonine-protein kinase ULK3	0	0	1	1
Poly [ADP-ribose] polymerase tankyrase-2	0	0	1	1
Bromodomain-containing protein 9	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Bromodomain-containing protein 7	0	0	1	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Sarcoma, Alveolar Soft Part

Synonyms(1)

Research Excerpts

Overview

Context

Research

Studies (80)

Protein Targets (906)

Sarcoma, Alveolar Soft Part

Synonyms(1)

Research Excerpts

Overview

Context

Research

Studies (80)

Drugs Studied (43)

Protein Targets (906)