Assay ID | Title | Year | Journal | Article |
AID132944 | Mean duration of lesions in HSV-1 infected mice, after administration of 0.1 % of compound intracutaneously | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID122202 | Effect of delayed treatment on mortality of systemically infected mice at 25 mg/kg per day administered through oral route after 72 hr of start of treatment | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID130018 | Cumulative lesions in HSV-1 infected mice, after administration of 0.1 % of compound intracutaneously | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID217419 | Proliferation of Vero cells by propagation on day 4 by measuring optical density (absorbance) at 100 ug/mL | 1987 | Journal of medicinal chemistry, Jul, Volume: 30, Issue:7
| 2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity. |
AID156701 | Antiviral activity against HSV-2 (G) in Primary Rabbit Kidney (PRK) cells | 1987 | Journal of medicinal chemistry, Jul, Volume: 30, Issue:7
| 2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity. |
AID130019 | Cumulative lesions in HSV-1 infected mice, after administration of 0.3 % of compound intracutaneously | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID120300 | In vivo evaluation for the percent survivors in systemic HSV-1 infection of Mice administered through oral route at a dose 100 mg/kg per day; NT=Not tested | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID87983 | Minimum inhibitory concentration of compound causing 50% inhibition of cytopathic effect induced by HSV-1(thymidine kinase deficient) in PRK cells | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID120303 | In vivo evaluation for the percent survivors in systemic HSV-1 infection of Mice administered through oral route at a dose 25 mg/kg per day | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID88118 | Minimum inhibitory concentration of compound causing 50% inhibition of cytopathic effect induced by HSV-2 in PRK cells | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID132945 | Mean duration of lesions in HSV-1 infected mice, after administration of 0.3 % of compound intracutaneously | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID120305 | In vivo evaluation for the percent survivors in systemic HSV-1 infection of Mice administered through oral route at a dose 5 mg/kg per day | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID87847 | Minimum inhibitory concentration causing 25% inhibition cytopathic effect induced by Herpes simplex virus-1 (Brand) in HEp-2 cells | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID120302 | In vivo evaluation for the percent survivors in systemic HSV-1 infection of Mice administered through oral route at a dose 2.5 mg/kg per day | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID87982 | Minimum inhibitory concentration of compound causing 50% inhibition of cytopathic effect induced by HSV-1 in PRK cells | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID217888 | Antiviral activity against HSV-1 (Brand) in Vero cells | 1987 | Journal of medicinal chemistry, Jul, Volume: 30, Issue:7
| 2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity. |
AID122195 | Effect of delayed treatment on mortality of systemically infected mice at 25 mg/kg per day administered Intraperitoneally after 24 hr of start of treatment | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID167149 | Minimum cytotoxic concentration of compound causing toxic effects on uninfected cells | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID120288 | In vivo evaluation for the percent survivors in systemic HSV-1 infection of Mice administered intraperitoneally at a dose 1 mg/kg per day | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID86209 | Proliferation of Hep-2 cells by propagation on day 4 by measuring optical density (absorbance) at 330 ug/mL | 1987 | Journal of medicinal chemistry, Jul, Volume: 30, Issue:7
| 2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity. |
AID87478 | Tested for in vitro anti-HSV-1 activity; active | 1990 | Journal of medicinal chemistry, Feb, Volume: 33, Issue:2
| Synthesis and antiviral and cytotoxic activity of iodohydrin and iodomethoxy derivatives of 5-vinyl-2'-deoxyuridines, 2'-fluoro-2'-deoxyuridine, and uridine. |
AID86208 | Proliferation of Hep-2 cells by propagation on day 4 by measuring optical density (absorbance) at 30 ug/mL | 1987 | Journal of medicinal chemistry, Jul, Volume: 30, Issue:7
| 2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity. |
AID81757 | Minimum toxic effect against HEp-2 cells. | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID87999 | Minimum inhibitory concentration causing 25% inhibition cytopathic effect induced by Herpes simplex virus(HSV) -2 (thymidine kinase deficient) in vero cells | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID87970 | Minimum inhibitory concentration causing 25% inhibition of cytopathic effect induced by Herpes simplex virus-1 (K979) in HEp-2 cells | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID87971 | Minimum inhibitory concentration causing 25% inhibition of cytopathic effect induced by herpes simplex virus (HSV)-1 (K979) in vero cells. | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID120304 | In vivo evaluation for the percent survivors in systemic HSV-1 infection of Mice administered through oral route at a dose 50 mg/kg per day | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID120291 | In vivo evaluation for the percent survivors in systemic HSV-1 infection of Mice administered intraperitoneally at a dose 50 mg/kg per day | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID122198 | Effect of delayed treatment on mortality of systemically infected mice at 25 mg/kg per day administered Intraperitoneally after 72 hr of start of treatment | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID84961 | Minimum inhibitory concentration against HSV-2. | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID122199 | Effect of delayed treatment on mortality of systemically infected mice at 25 mg/kg per day administered through oral route after 24 hr of start of treatment | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID156700 | Antiviral activity against HSV-1 (KOS) in Primary Rabbit Kidney (PRK) cells | 1987 | Journal of medicinal chemistry, Jul, Volume: 30, Issue:7
| 2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity. |
AID87968 | Minimum inhibitory concentration causing 25% inhibition cytopathic effect induced by Herpes simplex virus(HSV) -1 (thymidine kinase deficient) in HEp-2 cells | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID86207 | Proliferation of Hep-2 cells by propagation on day 4 by measuring optical density (absorbance) at 100 ug/mL | 1987 | Journal of medicinal chemistry, Jul, Volume: 30, Issue:7
| 2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity. |
AID122197 | Effect of delayed treatment on mortality of systemically infected mice at 25 mg/kg per day administered Intraperitoneally after 48 hr of start of treatment | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID83146 | Antiviral activity against VZV (Ellen) in human lung fibroblast (HLF-1) cells | 1987 | Journal of medicinal chemistry, Jul, Volume: 30, Issue:7
| 2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity. |
AID217420 | Proliferation of Vero cells by propagation on day 4 by measuring optical density (absorbance) at 30 ug/mL | 1987 | Journal of medicinal chemistry, Jul, Volume: 30, Issue:7
| 2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity. |
AID87974 | Minimum inhibitory concentration causing 25% inhibition of cytopathic effect induced by Herpes simplex virus(HSV) -1 (thymidine kinase deficient) in vero cells | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID120289 | In vivo evaluation for the percent survivors in systemic HSV-1 infection of Mice administered intraperitoneally at a dose 2.5 mg/kg per day; NT=Not tested | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID120148 | In vivo evaluation for the percent survivors in systemic HSV-1 infection of Mice administered intraperitoneally at a dose 10 mg/kg per day | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID122201 | Effect of delayed treatment on mortality of systemically infected mice at 25 mg/kg per day administered through oral route after 48 hr of start of treatment | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID167150 | Minimum cytotoxic concentration causing toxic effects on uninfected cells in rabbit | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID86215 | Antiviral activity against HSV-1 (Brand) in human epithelial (Hep-2) cells | 1987 | Journal of medicinal chemistry, Jul, Volume: 30, Issue:7
| 2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity. |
AID122200 | Effect of delayed treatment on mortality of systemically infected mice at 25 mg/kg per day administered through oral route after 3 hr of start of treatment | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID83893 | Minimum inhibitory concentration against HSV-1. | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID120147 | In vivo evaluation for the percent survivors in systemic HSV-1 infection of Mice administered intraperitoneally at a dose 100 mg/kg per day | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID120290 | In vivo evaluation for the percent survivors in systemic HSV-1 infection of Mice administered intraperitoneally at a dose 25 mg/kg per day | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID133584 | Mean survival time in HSV-1 infected mice, after peroral administration of 5 mg/kg of compound | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID133579 | Mean survival time in HSV-1 infected mice, after intraperitoneal administration of 0.5 mg/kg of compound | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID86216 | Antiviral activity against HSV-2 (K979) in human epithelial (Hep-2) cells | 1987 | Journal of medicinal chemistry, Jul, Volume: 30, Issue:7
| 2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity. |
AID122196 | Effect of delayed treatment on mortality of systemically infected mice at 25 mg/kg per day administered Intraperitoneally after 3 hr of start of treatment | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID88114 | Minimum inhibitory concentration causing 25% inhibition of cytopathic effect induced by Herpes simplex virus(HSV) -2 (thymidine kinase deficient) in HEp-2 cells | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID130021 | Cumulative mortality in percent of HSV-1 infected mice, after intraperitoneal administration of 0.5 mg/kg of compound | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID130025 | Cumulative mortality in percent of HSV-1 infected mice, after peroral administration of 5 mg/kg of compound | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
AID217421 | Proliferation of Vero cells by propagation on day 4 by measuring optical density (absorbance) at 330 ug/mL | 1987 | Journal of medicinal chemistry, Jul, Volume: 30, Issue:7
| 2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity. |
AID120292 | In vivo evaluation for the percent survivors in systemic HSV-1 infection of Mice administered intraperitoneally at a dose 5 mg/kg per day | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| 5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue. |
AID217889 | Antiviral activity against HSV-2 (K979) in Vero cells | 1987 | Journal of medicinal chemistry, Jul, Volume: 30, Issue:7
| 2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity. |
AID87969 | Minimum inhibitory concentration causing 25% inhibition of cytopathic effect induced by Herpes simplex virus-1 (Brand) in vero cells | 1988 | Journal of medicinal chemistry, Sep, Volume: 31, Issue:9
| Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |