Compounds > laurinterol
Page last updated: 2024-11-12

laurinterol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

laurinterol: an antimicrobial agent isolated from the marine alga Laurencia okamurai [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

laurinterol : A sesquiterpenoid isolated from Laurencia intermedia and Aplysia kurodai and has been found to exhibit antibacterial activity, [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID11471955
CHEBI ID66555
MeSH IDM0526566

Synonyms (8)

Synonym
laurinterol
C17136
CHEBI:66555
4-bromo-2-[(1s,2r,5r)-1,2-dimethylbicyclo[3.1.0]hex-2-yl]-5-methylphenol
4-bromo-2-[(1s,2r,5r)-1,2-dimethyl-2-bicyclo[3.1.0]hexanyl]-5-methylphenol
Q27135165
phenol, 4-bromo-2-[(1s,2r,5r)-1,2-dimethylbicyclo[3.1.0]hex-2-yl]-5-methyl-
AKOS040747014

Research Excerpts

Overview

Laurinterol is a marine sesquiterpene that has been known to have antimicrobial activity.

ExcerptReferenceRelevance
"Laurinterol is a marine sesquiterpene that has been known to have antimicrobial activity. "( Laurencia okamurai extract containing laurinterol induces apoptosis in melanoma cells.
Kim, MM; Kim, SK; Mendis, E, 2008)		2.06
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (4)

RoleDescription
metaboliteAny intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
apoptosis inducerAny substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
antibacterial agentA substance (or active part thereof) that kills or slows the growth of bacteria.
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitorAn EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of Na(+)/K(+)-transporting ATPase (EC 3.6.3.9).
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (3)

ClassDescription
sesquiterpenoidAny terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).
phenolsOrganic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring.
organobromine compoundA compound containing at least one carbon-bromine bond.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 18.21

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index18.21 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.97 (4.65)
Search Engine Demand Index10.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (18.21)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
acetogenins
Acetogenins: Polyketides of up to a few dozen carbons in length, formed by chain extension of multiple PROPIONATES and oxygenated to form tetrahydrofuran and lactone rings along the length of the chain. They are found in ANNONACEAE and other PLANTS. Related compounds cyclize to MACROLIDES.		2.0710
sesquiterpenes
[no description available]		3.360
aplysin
aplysin: Antineoplastic Agents, Alkylating, derived from Laurencia tristicha; structure in first source		7.2510
ConditionIndicatedRelationship StrengthStudiesTrials
Atypical Mycobacterial Infection, Disseminated
[description not available]		02.2510
Breast Cancer
[description not available]		07.2110
Breast Neoplasms
Tumors or cancer of the human BREAST.		02.2110
Malignant Melanoma
[description not available]		02.0410
B16 Melanoma
[description not available]		02.0410
Melanoma
A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)		07.0410