| Role | Compounds |
|---|
| 5-hydroxytryptamine 2a receptor agonist | 1 |
| 5-hydroxytryptamine 2a receptor inverse agonist | 1 |
| 5-hydroxytryptamine 2b receptor agonist | 2 |
| 5-hydroxytryptamine 2c receptor agonist | 2 |
| abortifacient | 5 |
| abscisic acid receptor agonist | 2 |
| acaricide | 61 |
| acid-base indicator | 9 |
| actin polymerisation inducer | 1 |
| actin polymerisation inhibitor | 4 |
| acyl donor | 1 |
| acyl-coa:cholesterol acyltransferase 2 inhibitor | 3 |
| adenosine a1 receptor agonist | 3 |
| adenosine a1 receptor antagonist | 4 |
| adenosine a2a receptor agonist | 2 |
| adenosine a2a receptor antagonist | 4 |
| adenosine a2b receptor agonist | 1 |
| adenosine a3 receptor agonist | 1 |
| adenosine a3 receptor antagonist | 1 |
| adenosine phosphodiesterase inhibitor | 1 |
| adenosine receptor antagonist | 3 |
| adenylate cyclase agonist | 2 |
| adjuvant | 9 |
| adrenergic agent | 11 |
| adrenergic agonist | 3 |
| adrenergic antagonist | 20 |
| adrenergic uptake inhibitor | 17 |
| affinity label | 2 |
| agonist | 2 |
| agrochemical | 148 |
| alarm pheromone | 3 |
| aldosterone antagonist | 3 |
| algal metabolite | 74 |
| alkylating agent | 52 |
| allelochemical | 8 |
| allergen | 95 |
| alpha-adrenergic agonist | 22 |
| alpha-adrenergic antagonist | 35 |
| alpha-adrenergic drug | 2 |
| alpha-secretase activator | 2 |
| ampa receptor agonist | 1 |
| ampa receptor antagonist | 1 |
| amphiphile | 3 |
| amphiprotic solvent | 1 |
| anabolic agent | 10 |
| anaesthesia adjuvant | 5 |
| anaesthetic | 10 |
| analgesic | 48 |
| androgen | 38 |
| androgen antagonist | 14 |
| androstane receptor agonist | 1 |
| angiogenesis inhibitor | 56 |
| angiogenesis modulating agent | 16 |
| angiotensin receptor agonist | 1 |
| angiotensin receptor antagonist | 12 |
| animal growth promotant | 3 |
| animal metabolite | 57 |
| antacid | 5 |
| antagonist | 1 |
| anthelminthic drug | 17 |
| anti-allergic agent | 59 |
| anti-anaemic agent | 2 |
| anti-arrhythmia drug | 59 |
| anti-asthmatic agent | 9 |
| anti-asthmatic drug | 35 |
| anti-estrogen | 8 |
| anti-hbv agent | 4 |
| anti-hiv agent | 26 |
| anti-hiv-1 agent | 14 |
| anti-hsv-1 agent | 8 |
| anti-hsv-2 agent | 1 |
| anti-inflammatory agent | 224 |
| anti-inflammatory drug | 50 |
| anti-obesity agent | 11 |
| anti-ulcer drug | 28 |
| antiamoebic agent | 8 |
| antiatherogenic agent | 4 |
| antiatherosclerotic agent | 4 |
| antiauxins | 1 |
| antibacterial agent | 184 |
| antibacterial drug | 162 |
| antibiotic insecticide | 2 |
| anticholesteremic drug | 16 |
| anticoagulant | 38 |
| anticonvulsant | 83 |
| anticoronaviral agent | 150 |
| antidepressant | 84 |
| antidiarrhoeal drug | 9 |
| antidote | 11 |
| antidote to benzodiazepine poisoning | 1 |
| antidote to curare poisoning | 4 |
| antidote to cyanide poisoning | 3 |
| antidote to opioid poisoning | 4 |
| antidote to organophosphate poisoning | 2 |
| antidote to paracetamol poisoning | 3 |
| antidote to sarin poisoning | 3 |
| antidyskinesia agent | 16 |
| antiemetic | 39 |
| antifeedant | 13 |
| antifibrinolytic drug | 4 |
| antifolate | 2 |
| antifouling biocide | 5 |
| antifungal agent | 129 |
| antifungal agrochemical | 102 |
| antifungal drug | 18 |
| antigen | 11 |
| antiglaucoma drug | 26 |
| antihyperplasia drug | 3 |
| antihypertensive agent | 153 |
| antihypotensive agent | 2 |
| antiinfective agent | 59 |
| antileishmanial agent | 17 |
| antilipemic drug | 30 |
| antimalarial | 60 |
| antimanic drug | 6 |
| antimetabolite | 58 |
| antimicrobial agent | 182 |
| antimicrobial drug | 3 |
| antimicrobial food preservative | 9 |
| antimitotic | 16 |
| antimutagen | 7 |
| antimycobacterial drug | 10 |
| antinematodal drug | 18 |
| antineoplastic agent | 896 |
| antioxidant | 241 |
| antiparasitic agent | 19 |
| antiparathyroid drug | 1 |
| antiparkinson drug | 41 |
| antiplasmodial drug | 11 |
| antiplatyhelmintic drug | 1 |
| antiprotozoal drug | 26 |
| antipruritic drug | 21 |
| antipsoriatic | 10 |
| antipsychotic agent | 16 |
| antipyretic | 47 |
| antirheumatic drug | 38 |
| antiseborrheic | 4 |
| antiseptic drug | 29 |
| antispasmodic drug | 20 |
| antispermatogenic agent | 5 |
| antithyroid drug | 5 |
| antitrichomonal drug | 4 |
| antitubercular agent | 19 |
| antitussive | 20 |
| antiviral agent | 73 |
| antiviral drug | 66 |
| anxiogenic | 1 |
| anxiolytic drug | 45 |
| ap-1 antagonist | 2 |
| apoptosis inducer | 263 |
| apoptosis inhibitor | 36 |
| appetite depressant | 10 |
| appetite enhancer | 3 |
| aprotic solvent | 1 |
| aquaretic | 3 |
| arabidopsis thaliana metabolite | 7 |
| aryl hydrocarbon receptor agonist | 9 |
| aryl hydrocarbon receptor antagonist | 1 |
| aspergillus metabolite | 57 |
| astringent | 10 |
| atp synthase inhibitor | 3 |
| atp/adp translocase inhibitor | 1 |
| aurora kinase inhibitor | 7 |
| autophagy inducer | 15 |
| autophagy inhibitor | 10 |
| auxin | 7 |
| avicide | 13 |
| axin stabilizer | 2 |
| b-cell lymphoma 2 inhibitor | 3 |
| b-raf inhibitor | 7 |
| bacterial metabolite | 245 |
| bacterial xenobiotic metabolite | 42 |
| base | 1 |
| beta-adrenergic agonist | 24 |
| beta-adrenergic antagonist | 30 |
| bile acid metabolite | 1 |
| bile therapy drug | 1 |
| biological pigment | 20 |
| biomarker | 43 |
| bleaching agent | 4 |
| blood substitute | 5 |
| bone density conservation agent | 37 |
| bone morphogenetic protein receptor antagonist | 2 |
| bradykinin receptor agonist | 1 |
| bradykinin receptor antagonist | 2 |
| bradykinin receptor b2 agonist | 3 |
| brassica napus metabolite | 10 |
| brassinosteroid biosynthesis inhibitor | 1 |
| breast cancer resistance protein inhibitor | 2 |
| bridged diphenyl acaricide | 1 |
| bromodomain-containing protein 4 inhibitor | 2 |
| bronchoconstrictor agent | 7 |
| bronchodilator agent | 35 |
| buffer | 9 |
| c-jun n-terminal kinase inhibitor | 3 |
| c-met tyrosine kinase inhibitor | 3 |
| c-x-c chemokine receptor type 4 antagonist | 1 |
| caenorhabditis elegans metabolite | 7 |
| calcimimetic | 2 |
| calcitonin gene-related peptide receptor antagonist | 1 |
| calcium channel agonist | 4 |
| calcium channel blocker | 36 |
| calcium channel modulator | 1 |
| calcium ionophore | 2 |
| calcium-dependent antibiotics | 1 |
| calmodulin antagonist | 4 |
| calpain inhibitor | 3 |
| cannabinoid receptor agonist | 5 |
| capsaicin receptor agonist | 1 |
| capsaicin receptor antagonist | 4 |
| carbamate insecticide | 13 |
| carbamylphosphate synthetase i activator | 1 |
| carcinogenic agent | 139 |
| cardioprotective agent | 33 |
| cardiotonic drug | 25 |
| cardiotoxic agent | 5 |
| cardiovascular drug | 18 |
| carotenoid biosynthesis inhibitor | 10 |
| carotogenesis inhibitor | 1 |
| catalyst | 12 |
| cathartic | 3 |
| cathepsin b inhibitor | 3 |
| cathepsin l (ec 3.4.22.15) inhibitor | 3 |
| cb1 receptor agonist | 1 |
| cb1 receptor antagonist | 3 |
| cb2 receptor agonist | 3 |
| cb2 receptor antagonist | 1 |
| cell dedifferentiation agent | 1 |
| cellulose synthesis inhibitor | 3 |
| central nervous system depressant | 23 |
| central nervous system drug | 8 |
| central nervous system stimulant | 19 |
| cetp inhibitor | 3 |
| cftr potentiator | 2 |
| chaetomium metabolite | 6 |
| chain carrier | 1 |
| chelator | 38 |
| chemokine receptor 2 antagonist | 1 |
| chemokine receptor 5 antagonist | 2 |
| cholecystokinin antagonist | 3 |
| cholinergic agonist | 2 |
| cholinergic antagonist | 22 |
| cholinergic drug | 10 |
| cholinesterase reactivator | 5 |
| chromatographic reagent | 11 |
| chromogenic compound | 27 |
| chromophore | 5 |
| cis-golgi arfgef gbf inhibitor | 1 |
| coccidiostat | 6 |
| coenzyme | 12 |
| cofactor | 41 |
| collagen cross-linking inhibitor | 2 |
| colorimetric reagent | 3 |
| colour indicator | 1 |
| compatible osmolytes | 2 |
| contraceptive drug | 13 |
| copper chelator | 10 |
| coral metabolite | 3 |
| corrosion inhibitor | 1 |
| corticotropin-releasing factor receptor antagonist | 2 |
| cosmetic | 3 |
| cpsf3 inhibitor | 1 |
| cross-linking reagent | 12 |
| crustacean metabolite | 2 |
| curing agent | 2 |
| cyanotoxin | 3 |
| cyclooxygenase 1 inhibitor | 23 |
| cyclooxygenase 2 inhibitor | 45 |
| cyclooxygenase 3 inhibitor | 5 |
| cysteine protease inhibitor | 6 |
| cytochrome-b6f complex inhibitor | 1 |
| cytokinin | 5 |
| daphnia galeata metabolite | 6 |
| daphnia magna metabolite | 33 |
| daphnia tenebrosa metabolite | 3 |
| defoliant | 4 |
| delta-opioid receptor agonist | 7 |
| delta-opioid receptor antagonist | 2 |
| dermatologic drug | 21 |
| detergent | 8 |
| diagnostic agent | 18 |
| dinitrophenol insecticide | 1 |
| disinfectant | 18 |
| diuretic | 28 |
| dna synthesis inhibitor | 30 |
| dopamine agonist | 26 |
| dopamine receptor d2 antagonist | 2 |
| dopamine uptake inhibitor | 15 |
| dopaminergic agent | 12 |
| dopaminergic antagonist | 49 |
| drug | 1 |
| drug allergen | 79 |
| drug metabolite | 95 |
| dye | 27 |
| ec 1.1.1.1 (alcohol dehydrogenase) inhibitor | 2 |
| ec 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (nad(+))] inhibitor | 1 |
| ec 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor | 3 |
| ec 1.1.1.153 [sepiapterin reductase (l-erythro-7,8-dihydrobiopterin forming)] inhibitor | 2 |
| ec 1.1.1.159 (7alpha-hydroxysteroid dehydrogenase) inhibitor | 1 |
| ec 1.1.1.184 [carbonyl reductase (nadph)] inhibitor | 2 |
| ec 1.1.1.188 (prostaglandin-f synthase) inhibitor | 1 |
| ec 1.1.1.189 (prostaglandin-e2 9-reductase) inhibitor | 1 |
| ec 1.1.1.205 (imp dehydrogenase) inhibitor | 5 |
| ec 1.1.1.21 (aldehyde reductase) inhibitor | 13 |
| ec 1.1.1.210 [3beta(or 20alpha)-hydroxysteroid dehydrogenase] inhibitor | 1 |
| ec 1.1.1.25 (shikimate dehydrogenase) inhibitor | 4 |
| ec 1.1.1.267 (1-deoxy-d-xylulose-5-phosphate reductoisomerase) inhibitor | 1 |
| ec 1.1.1.34/ec 1.1.1.88 (hydroxymethylglutaryl-coa reductase) inhibitor | 7 |
| ec 1.1.1.37 (malate dehydrogenase) inhibitor | 1 |
| ec 1.1.1.42 (isocitrate dehydrogenase) inhibitor | 3 |
| ec 1.1.1.44 (nadp(+)-dependent decarboxylating phosphogluconate dehydrogenase) inhibitor | 1 |
| ec 1.1.3.13 (alcohol oxidase) inhibitor | 1 |
| ec 1.1.5.3 (glycerol-3-phosphate dehydrogenase) inhibitor | 1 |
| ec 1.10.3.1 (catechol oxidase) inhibitor | 1 |
| ec 1.10.3.2 (laccase) inhibitor | 1 |
| ec 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor | 2 |
| ec 1.11.1.11 (l-ascorbate peroxidase) inhibitor | 2 |
| ec 1.11.1.6 (catalase) inhibitor | 1 |
| ec 1.11.1.9 (glutathione peroxidase) inhibitor | 2 |
| ec 1.11.2.2 (myeloperoxidase) inhibitor | 1 |
| ec 1.13.11.11 (tryptophan 2,3-dioxygenase) inhibitor | 1 |
| ec 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor | 1 |
| ec 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor | 6 |
| ec 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor | 3 |
| ec 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor | 9 |
| ec 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor | 16 |
| ec 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor | 2 |
| ec 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor | 1 |
| ec 1.14.11.1 (gamma-butyrobetaine dioxygenase) inhibitor | 1 |
| ec 1.14.11.2 (procollagen-proline dioxygenase) inhibitor | 3 |
| ec 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor | 2 |
| ec 1.14.13.132 (squalene monooxygenase) inhibitor | 5 |
| ec 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor | 2 |
| ec 1.14.13.39 (nitric oxide synthase) inhibitor | 21 |
| ec 1.14.13.67 (quinine 3-monooxygenase) inhibitor | 1 |
| ec 1.14.13.70 (sterol 14alpha-demethylase) inhibitor | 14 |
| ec 1.14.13.72 (methylsterol monooxygenase) inhibitor | 1 |
| ec 1.14.13.78 (ent-kaurene oxidase) inhibitor | 1 |
| ec 1.14.13.97 (taurochenodeoxycholate 6alpha-hydroxylase) inhibitor | 1 |
| ec 1.14.14.14 (aromatase) inhibitor | 9 |
| ec 1.14.14.154 (sterol 14alpha-demethylase) inhibitor | 1 |
| ec 1.14.14.91 ( trans-cinnamate 4-monooxygenase) inhibitor | 1 |
| ec 1.14.14.94 (leukotriene-b4 20-monooxygenase) inhibitor | 1 |
| ec 1.14.15.3 (alkane 1-monooxygenase) inhibitor | 1 |
| ec 1.14.15.4 (steroid 11beta-monooxygenase) inhibitor | 1 |
| ec 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving) inhibitor | 1 |
| ec 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor | 3 |
| ec 1.14.17.1 (dopamine beta-monooxygenase) inhibitor | 2 |
| ec 1.14.18.1 (tyrosinase) inhibitor | 18 |
| ec 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor | 39 |
| ec 1.14.99.66 (lysine-specific histone demethylase 1a) inhibitor | 1 |
| ec 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor | 2 |
| ec 1.15.1.1 (superoxide dismutase) inhibitor | 2 |
| ec 1.17.3.2 (xanthine oxidase) inhibitor | 8 |
| ec 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor | 4 |
| ec 1.2.1.11 (aspartate-semialdehyde dehydrogenase) inhibitor | 1 |
| ec 1.2.1.12 [glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)] inhibitor | 1 |
| ec 1.2.1.3 [aldehyde dehydrogenase (nad(+))] inhibitor | 7 |
| ec 1.2.1.88 (l-glutamate gamma-semialdehyde dehydrogenase) inhibitor | 1 |
| ec 1.2.3.1 (aldehyde oxidase) inhibitor | 2 |
| ec 1.21.3.3 (reticuline oxidase) inhibitor | 1 |
| ec 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (nadp(+))] inhibitor | 5 |
| ec 1.3.1.43 (arogenate dehydrogenase) inhibitor | 1 |
| ec 1.3.1.70 (delta(14)-sterol reductase) inhibitor | 1 |
| ec 1.3.1.72 (delta(24)-sterol reductase) inhibitor | 2 |
| ec 1.3.1.8 [acyl-coa dehydrogenase (nadp(+))] inhibitor | 2 |
| ec 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (nadh)] inhibitor | 2 |
| ec 1.3.3.4 (protoporphyrinogen oxidase) inhibitor | 9 |
| ec 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor | 8 |
| ec 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor | 2 |
| ec 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor | 2 |
| ec 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor | 1 |
| ec 1.4.3.22 (diamine oxidase) inhibitor | 1 |
| ec 1.4.3.3 (d-amino-acid oxidase) inhibitor | 1 |
| ec 1.4.3.4 (monoamine oxidase) inhibitor | 18 |
| ec 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitor | 1 |
| ec 1.5.1.3 (dihydrofolate reductase) inhibitor | 11 |
| ec 1.6.3.1. [nad(p)h oxidase (h2o2-forming)] inhibitor | 2 |
| ec 1.6.5.2 [nad(p)h dehydrogenase (quinone)] inhibitor | 4 |
| ec 1.6.5.3 [nadh:ubiquinone reductase (h(+)-translocating)] inhibitor | 2 |
| ec 1.8.1.12 (trypanothione-disulfide reductase) inhibitor | 5 |
| ec 1.8.1.4 (dihydrolipoyl dehydrogenase) inhibitor | 1 |
| ec 1.8.1.9 (thioredoxin reductase) inhibitor | 2 |
| ec 1.8.5.4 (sulfide:quinone reductase) inhibitor | 1 |
| ec 1.9.3.1 (cytochrome c oxidase) inhibitor | 3 |
| ec 2.1.1.116 [3'-hydroxy-n-methyl-(s)-coclaurine 4'-o-methyltransferase] inhibitor | 2 |
| ec 2.1.1.122 [(s)-tetrahydroprotoberberine n-methyltransferase] inhibitor | 2 |
| ec 2.1.1.4 (acetylserotonin o-methyltransferase) inhibitor | 1 |
| ec 2.1.1.43 (enhancer of zeste homolog 2) inhibitor | 1 |
| ec 2.1.1.45 (thymidylate synthase) inhibitor | 2 |
| ec 2.1.1.6 (catechol o-methyltransferase) inhibitor | 2 |
| ec 2.1.1.72 [site-specific dna-methyltransferase (adenine-specific)] inhibitor | 1 |
| ec 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor | 1 |
| ec 2.1.1.8 (histamine n-methyltransferase) inhibitor | 1 |
| ec 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor | 1 |
| ec 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor | 1 |
| ec 2.2.1.6 (acetolactate synthase) inhibitor | 9 |
| ec 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor | 1 |
| ec 2.3.1.20 (diacylglycerol o-acyltransferase) inhibitor | 1 |
| ec 2.3.1.21 (carnitine o-palmitoyltransferase) inhibitor | 1 |
| ec 2.3.1.24 (sphingosine n-acyltransferase) inhibitor | 1 |
| ec 2.3.1.26 (sterol o-acyltransferase) inhibitor | 1 |
| ec 2.3.1.48 (histone acetyltransferase) inhibitor | 5 |
| ec 2.3.1.5 (arylamine n-acetyltransferase) inhibitor | 1 |
| ec 2.3.1.50 (serine c-palmitoyltransferase) inhibitor | 2 |
| ec 2.3.1.85 (fatty acid synthase) inhibitor | 5 |
| ec 2.3.1.97 (glycylpeptide n-tetradecanoyltransferase) inhibitor | 1 |
| ec 2.3.2.13 (protein-glutamine gamma-glutamyltransferase) inhibitor | 2 |
| ec 2.3.2.2 (gamma-glutamyltransferase) inhibitor | 1 |
| ec 2.3.2.52 (beta-n-acetylhexosaminidase) inhibitor | 1 |
| ec 2.3.3.1 [citrate (si)-synthase] inhibitor | 2 |
| ec 2.3.3.8 (atp citrate synthase) inhibitor | 2 |
| ec 2.4.1.1 (glycogen phosphorylase) inhibitor | 1 |
| ec 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor | 2 |
| ec 2.4.1.17 (glucuronosyltransferase) inhibitor | 1 |
| ec 2.4.1.231 [alpha,alpha-trehalose phosphorylase (configuration-retaining)] inhibitor | 1 |
| ec 2.4.1.64 (alpha,alpha-trehalose phosphorylase) inhibitor | 1 |
| ec 2.4.1.80 (ceramide glucosyltransferase) inhibitor | 3 |
| ec 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor | 3 |
| ec 2.4.2.14 (amidophosphoribosyltransferase) inhibitor | 1 |
| ec 2.4.2.30 (nad(+) adp-ribosyltransferase) inhibitor | 11 |
| ec 2.4.2.4 (thymidine phosphorylase) inhibitor | 2 |
| ec 2.4.2.8 (hypoxanthine phosphoribosyltransferase) inhibitor | 1 |
| ec 2.5.1.1 (dimethylallyltranstransferase) inhibitor | 2 |
| ec 2.5.1.15 (dihydropteroate synthase) inhibitor | 11 |
| ec 2.5.1.18 (glutathione transferase) inhibitor | 5 |
| ec 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor | 1 |
| ec 2.5.1.21 (squalene synthase) inhibitor | 2 |
| ec 2.5.1.46 (deoxyhypusine synthase) inhibitor | 1 |
| ec 2.5.1.49 (o-acetylhomoserine aminocarboxypropyltransferase) inhibitor | 1 |
| ec 2.5.1.58 (protein farnesyltransferase) inhibitor | 9 |
| ec 2.5.1.59 (protein geranylgeranyltransferase type i) inhibitor | 4 |
| ec 2.5.1.6 (methionine adenosyltransferase) inhibitor | 1 |
| ec 2.5.1.7 (udp-n-acetylglucosamine 1-carboxyvinyltransferase) inhibitor | 3 |
| ec 2.5.1.9 (riboflavin synthase) inhibitor | 1 |
| ec 2.6.1.13 (ornithine aminotransferase) inhibitor | 1 |
| ec 2.6.1.16 (glutamine--fructose-6-phosphate transaminase (isomerizing)) inhibitor | 1 |
| ec 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor | 3 |
| ec 2.6.1.40 [(r)-3-amino-2-methylpropionate--pyruvate transaminase] inhibitor | 1 |
| ec 2.7.1.1 (hexokinase) inhibitor | 3 |
| ec 2.7.1.105 (6-phosphofructo-2-kinase) inhibitor | 1 |
| ec 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor | 1 |
| ec 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor | 21 |
| ec 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor | 1 |
| ec 2.7.1.33 (pantothenate kinase) inhibitor | 8 |
| ec 2.7.1.40 (pyruvate kinase) inhibitor | 1 |
| ec 2.7.1.91 (sphingosine kinase) inhibitor | 2 |
| ec 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor | 39 |
| ec 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor | 20 |
| ec 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor | 23 |
| ec 2.7.11.10 (ikappab kinase) inhibitor | 3 |
| ec 2.7.11.11 (camp-dependent protein kinase) inhibitor | 2 |
| ec 2.7.11.12 (cgmp-dependent protein kinase) inhibitor | 1 |
| ec 2.7.11.13 (protein kinase c) inhibitor | 19 |
| ec 2.7.11.17 (ca(2+)/calmodulin-dependent protein kinase) inhibitor | 1 |
| ec 2.7.11.18 (myosin-light-chain kinase) inhibitor | 4 |
| ec 2.7.11.2 - [pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitor | 1 |
| ec 2.7.11.20 (elongation factor 2 kinase) inhibitor | 1 |
| ec 2.7.11.21 (polo kinase) inhibitor | 2 |
| ec 2.7.11.22 (cyclin-dependent kinase) inhibitor | 19 |
| ec 2.7.11.24 (mitogen-activated protein kinase) inhibitor | 23 |
| ec 2.7.11.26 (tau-protein kinase) inhibitor | 16 |
| ec 2.7.11.31 {[hydroxymethylglutaryl-coa reductase (nadph)] kinase} activator | 1 |
| ec 2.7.11.31 {[hydroxymethylglutaryl-coa reductase (nadph)] kinase} inhibitor | 1 |
| ec 2.7.12.1 (dual-specificity kinase) inhibitor | 2 |
| ec 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor | 3 |
| ec 2.7.3.2 (creatine kinase) inhibitor | 1 |
| ec 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor | 1 |
| ec 2.7.7.48 (rna-directed rna polymerase) inhibitor | 4 |
| ec 2.7.7.49 (rna-directed dna polymerase) inhibitor | 6 |
| ec 2.7.7.6 (rna polymerase) inhibitor | 8 |
| ec 2.7.7.7 (dna-directed dna polymerase) inhibitor | 7 |
| ec 3.1.1.1 (carboxylesterase) inhibitor | 7 |
| ec 3.1.1.3 (triacylglycerol lipase) inhibitor | 6 |
| ec 3.1.1.4 (phospholipase a2) inhibitor | 11 |
| ec 3.1.1.5 (lysophospholipase) inhibitor | 1 |
| ec 3.1.1.64 (retinoid isomerohydrolase) inhibitor | 1 |
| ec 3.1.1.7 (acetylcholinesterase) inhibitor | 101 |
| ec 3.1.1.8 (cholinesterase) inhibitor | 45 |
| ec 3.1.27.3 (ribonuclease t1) inhibitor | 1 |
| ec 3.1.3.1 (alkaline phosphatase) inhibitor | 6 |
| ec 3.1.3.11 (fructose-bisphosphatase) inhibitor | 1 |
| ec 3.1.3.16 (phosphoprotein phosphatase) inhibitor | 10 |
| ec 3.1.3.25 (inositol-phosphate phosphatase) inhibitor | 1 |
| ec 3.1.3.41 (4-nitrophenylphosphatase) inhibitor | 2 |
| ec 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor | 8 |
| ec 3.1.4.* (phosphoric diester hydrolase) inhibitor | 15 |
| ec 3.1.4.11 (phosphoinositide phospholipase c) inhibitor | 1 |
| ec 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor | 2 |
| ec 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor | 3 |
| ec 3.1.4.35 (3',5'-cyclic-gmp phosphodiesterase) inhibitor | 5 |
| ec 3.1.4.53 (3',5'-cyclic-amp phosphodiesterase) inhibitor | 1 |
| ec 3.2.1.* (glycosidase) inhibitor | 1 |
| ec 3.2.1.1 (alpha-amylase) inhibitor | 4 |
| ec 3.2.1.10 (oligo-1,6-glucosidase) inhibitor | 1 |
| ec 3.2.1.114 (mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) inhibitor | 2 |
| ec 3.2.1.166 (heparanase) inhibitor | 1 |
| ec 3.2.1.18 (exo-alpha-sialidase) inhibitor | 9 |
| ec 3.2.1.20 (alpha-glucosidase) inhibitor | 18 |
| ec 3.2.1.23 (beta-galactosidase) inhibitor | 1 |
| ec 3.2.1.24 (alpha-mannosidase) inhibitor | 1 |
| ec 3.2.1.28 (alpha,alpha-trehalase) inhibitor | 2 |
| ec 3.2.1.45 (glucosylceramidase) inhibitor | 1 |
| ec 3.3.2.10 (soluble epoxide hydrolase) inhibitor | 1 |
| ec 3.4.11.* (aminopeptidase) inhibitor | 1 |
| ec 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor | 1 |
| ec 3.4.13.19 (membrane dipeptidase) inhibitor | 2 |
| ec 3.4.14.2 (dipeptidyl-peptidase ii) inhibitor | 1 |
| ec 3.4.14.5 (dipeptidyl-peptidase iv) inhibitor | 5 |
| ec 3.4.15.1 (peptidyl-dipeptidase a) inhibitor | 30 |
| ec 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor | 1 |
| ec 3.4.19.3 (pyroglutamyl-peptidase i) inhibitor | 3 |
| ec 3.4.21.26 (prolyl oligopeptidase) inhibitor | 22 |
| ec 3.4.21.37 (leukocyte elastase) inhibitor | 2 |
| ec 3.4.21.4 (trypsin) inhibitor | 1 |
| ec 3.4.21.5 (thrombin) inhibitor | 9 |
| ec 3.4.21.6 (coagulation factor xa) inhibitor | 5 |
| ec 3.4.21.61 (kexin) inhibitor | 1 |
| ec 3.4.22.52 (calpain-1) inhibitor | 2 |
| ec 3.4.22.53 (calpain-2) inhibitor | 2 |
| ec 3.4.22.69 (sars coronavirus main proteinase) inhibitor | 16 |
| ec 3.4.23.* (aspartic endopeptidase) inhibitor | 1 |
| ec 3.4.23.15 (renin) inhibitor | 1 |
| ec 3.4.23.46 (memapsin 2) inhibitor | 6 |
| ec 3.4.24.11 (neprilysin) inhibitor | 1 |
| ec 3.4.24.24 (gelatinase a) inhibitor | 3 |
| ec 3.4.24.35 (gelatinase b) inhibitor | 3 |
| ec 3.4.24.71 (endothelin-converting enzyme 1) inhibitor | 1 |
| ec 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor | 2 |
| ec 3.5.1.108 (udp-3-o-acyl-n-acetylglucosamine deacetylase) inhibitor | 1 |
| ec 3.5.1.19 (nicotinamidase) inhibitor | 1 |
| ec 3.5.1.2 (glutaminase) inhibitor | 2 |
| ec 3.5.1.23 (ceramidase) inhibitor | 1 |
| ec 3.5.1.4 (amidase) inhibitor | 6 |
| ec 3.5.1.5 (urease) inhibitor | 3 |
| ec 3.5.1.88 (peptide deformylase) inhibitor | 1 |
| ec 3.5.1.98 (histone deacetylase) inhibitor | 31 |
| ec 3.5.1.99 (fatty acid amide hydrolase) inhibitor | 4 |
| ec 3.5.2.6 (beta-lactamase) inhibitor | 8 |
| ec 3.5.4.1 (cytosine deaminase) inhibitor | 1 |
| ec 3.5.4.4 (adenosine deaminase) inhibitor | 6 |
| ec 3.5.5.1 (nitrilase) inhibitor | 2 |
| ec 3.6.1.3 (adenosinetriphosphatase) inhibitor | 1 |
| ec 3.6.3.10 (h(+)/k(+)-exchanging atpase) inhibitor | 9 |
| ec 3.6.3.14 (h(+)-transporting two-sector atpase) inhibitor | 3 |
| ec 3.6.3.44 (xenobiotic-transporting atpase) inhibitor | 3 |
| ec 3.6.3.49 (channel-conductance-controlling atpase) inhibitor | 2 |
| ec 3.6.3.8 (ca(2+)-transporting atpase) inhibitor | 5 |
| ec 3.6.3.9 (na(+)/k(+)-transporting atpase) inhibitor | 13 |
| ec 3.6.5.2 (small monomeric gtpase) inhibitor | 2 |
| ec 3.6.5.5 (dynamin gtpase) inhibitor | 2 |
| ec 4.1.1.17 (ornithine decarboxylase) inhibitor | 3 |
| ec 4.1.1.23 (orotidine-5'-phosphate decarboxylase) inhibitor | 2 |
| ec 4.1.1.28 (aromatic-l-amino-acid decarboxylase) inhibitor | 4 |
| ec 4.1.1.39 (ribulose-bisphosphate carboxylase) inhibitor | 1 |
| ec 4.1.1.50 (adenosylmethionine decarboxylase) inhibitor | 1 |
| ec 4.2.1.1 (carbonic anhydrase) inhibitor | 11 |
| ec 4.2.1.22 (cystathionine beta-synthase) inhibitor | 2 |
| ec 4.2.1.3 (aconitate hydratase) inhibitor | 1 |
| ec 4.2.1.94 (scytalone dehydratase) inhibitor | 1 |
| ec 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor | 3 |
| ec 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor | 3 |
| ec 4.3.1.24 (phenylalanine ammonia-lyase) inhibitor | 1 |
| ec 4.3.1.3 (histidine ammonia-lyase) inhibitor | 2 |
| ec 4.4.1.11 (methionine gamma-lyase) inhibitor | 1 |
| ec 4.4.1.14 (1-aminocyclopropane-1-carboxylate synthase) inhibitor | 1 |
| ec 4.6.1.1 (adenylate cyclase) inhibitor | 2 |
| ec 4.6.1.2 (guanylate cyclase) inhibitor | 3 |
| ec 5.1.3.2 (udp-glucose 4-epimerase) inhibitor | 1 |
| ec 5.3.1.1 (triose-phosphate isomerase) inhibitor | 1 |
| ec 5.3.3.5 (cholestenol delta-isomerase) inhibitor | 4 |
| ec 5.4.3.2 (lysine 2,3-aminomutase) inhibitor | 1 |
| ec 5.4.99.7 (lanosterol synthase) inhibitor | 1 |
| ec 5.99.1.2 (dna topoisomerase) inhibitor | 19 |
| ec 5.99.1.3 [dna topoisomerase (atp-hydrolysing)] inhibitor | 22 |
| ec 6.1.1.11 (serine--trna ligase) inhibitor | 1 |
| ec 6.1.1.2 (tryptophan--trna ligase) inhibitor | 2 |
| ec 6.1.1.4 (leucine--trna ligase) inhibitor | 1 |
| ec 6.1.1.6 (lysine--trna ligase) inhibitor | 1 |
| ec 6.2.1.3 (long-chain-fatty-acid--coa ligase) inhibitor | 4 |
| ec 6.3.1.2 (glutamate--ammonia ligase) inhibitor | 3 |
| ec 6.3.2.2 (glutamate--cysteine ligase) inhibitor | 2 |
| ec 6.3.4.2 [ctp synthase (glutamine hydrolyzing)] inhibitor | 1 |
| ec 6.3.5.1 [nad(+) synthase (glutamine-hydrolysing)] inhibitor | 1 |
| ec 6.3.5.2 [gmp synthase (glutamine-hydrolysing)] inhibitor | 1 |
| ec 6.3.5.3 (phosphoribosylformylglycinamidine synthase) inhibitor | 1 |
| ec 6.3.5.4 [asparagine synthase (glutamine-hydrolysing)] inhibitor | 1 |
| ec 6.3.5.5 [carbamoyl-phosphate synthase (glutamine-hydrolysing)] inhibitor | 1 |
| ec 6.4.1.1 (pyruvate carboxylase) inhibitor | 2 |
| ec 6.4.1.2 (acetyl-coa carboxylase) inhibitor | 9 |
| ecdysone agonist | 1 |
| ectoparasiticide | 2 |
| effector | 1 |
| electron acceptor | 1 |
| electron donor | 3 |
| electrophilic reagent | 2 |
| emetic | 5 |
| emulsifier | 2 |
| endocrine disruptor | 5 |
| endothelin receptor antagonist | 6 |
| environmental contaminant | 253 |
| environmental food contaminant | 2 |
| enzyme inhibitor | 3 |
| enzyme mimic | 1 |
| epidermal growth factor receptor antagonist | 13 |
| epitope | 56 |
| ergosterol biosynthesis inhibitor | 2 |
| erythropoietin inhibitor | 1 |
| escherichia coli metabolite | 334 |
| estrogen | 18 |
| estrogen antagonist | 7 |
| estrogen receptor agonist | 9 |
| estrogen receptor antagonist | 9 |
| estrogen receptor modulator | 9 |
| ethylene releasers | 1 |
| eugeroic | 1 |
| eukaryotic initiation factor 4f inhibitor | 2 |
| eukaryotic metabolite | 2 |
| eukaryotic translation elongation factor 1alpha 1 inhibitor | 1 |
| excipient | 3 |
| excitatory amino acid agonist | 3 |
| excitatory amino acid antagonist | 2 |
| expectorant | 5 |
| explosive | 21 |
| farnesoid x receptor agonist | 1 |
| fatty acid oxidation inhibitor | 1 |
| fatty acid synthesis inhibitor | 3 |
| female contraceptive drug | 4 |
| ferroptosis inducer | 18 |
| ferroptosis inhibitor | 29 |
| ferroptosis suppressor protein 1 inhibitor | 1 |
| fertilizer | 19 |
| fibrin modulating drug | 3 |
| fibroblast growth factor receptor antagonist | 8 |
| film-forming compound | 1 |
| first generation antipsychotic | 15 |
| fixative | 4 |
| flame retardant | 7 |
| flavouring agent | 63 |
| flour treatment agent | 5 |
| fluorescence quencher | 1 |
| fluorescent dye | 9 |
| fluorescent probe | 13 |
| fluorochrome | 120 |
| food acidity regulator | 10 |
| food additive | 5 |
| food additive carrier | 1 |
| food anticaking agent | 4 |
| food antioxidant | 9 |
| food bleaching agent | 1 |
| food bulking agent | 1 |
| food colour retention agent | 2 |
| food colouring | 11 |
| food component | 12 |
| food emulsifier | 3 |
| food firming agent | 1 |
| food humectant | 3 |
| food packaging gas | 5 |
| food preservative | 5 |
| food propellant | 4 |
| food stabiliser | 1 |
| food thickening agent | 2 |
| forkhead box protein o1 inhibitor | 1 |
| fossil fuel | 1 |
| fragrance | 42 |
| fuel | 6 |
| fuel additive | 6 |
| fumigant | 5 |
| fumigant insecticide | 5 |
| fundamental metabolite | 52 |
| fungal metabolite | 108 |
| fungal xenobiotic metabolite | 9 |
| fungicide | 13 |
| g-protein-coupled receptor agonist | 4 |
| g-protein-coupled receptor antagonist | 1 |
| gaba agent | 2 |
| gaba agonist | 8 |
| gaba antagonist | 7 |
| gaba modulator | 16 |
| gaba reuptake inhibitor | 3 |
| gaba-gated chloride channel antagonist | 6 |
| gabaa receptor agonist | 6 |
| gabaa receptor antagonist | 1 |
| gabab receptor agonist | 1 |
| gamma-secretase modulator | 1 |
| gap junctional intercellular communication inhibitor | 2 |
| gastrointestinal drug | 17 |
| general anaesthetic | 7 |
| genotoxin | 35 |
| geroprotector | 175 |
| ghb receptor agonist | 1 |
| gibberellin biosynthesis inhibitor | 1 |
| glioma-associated oncogene inhibitor | 4 |
| glucagon-like peptide-1 receptor agonist | 2 |
| glucagon-like peptide-2 receptor agonist | 1 |
| glucocorticoid receptor agonist | 5 |
| glutamate transporter activator | 1 |
| glutamine antagonist | 3 |
| glutathione depleting agent | 1 |
| glycerophosphoinositol synthesis inhibitor | 1 |
| glycine receptor agonist | 2 |
| glycine receptor antagonist | 2 |
| glycine transporter 1 inhibitor | 1 |
| glycine transporter 2 inhibitor | 2 |
| gnrh antagonist | 1 |
| gonadotropin releasing hormone agonist | 5 |
| good's buffer substance | 1 |
| gout suppressant | 6 |
| greenhouse gas | 5 |
| gut flora metabolite | 1 |
| h1-receptor agonist | 1 |
| h1-receptor antagonist | 64 |
| h2-receptor antagonist | 10 |
| h3-receptor agonist | 3 |
| h3-receptor antagonist | 2 |
| h4-receptor agonist | 2 |
| hallucinogen | 12 |
| hapten | 30 |
| hedgehog signaling pathway inhibitor | 6 |
| hematologic agent | 6 |
| hepatic steatosis inducing agent | 1 |
| hepatitis c protease inhibitor | 9 |
| hepatitis c virus nonstructural protein 5a inhibitor | 3 |
| hepatoprotective agent | 48 |
| hepatotoxic agent | 36 |
| herbicide | 114 |
| herbicide safener | 1 |
| histamine agonist | 6 |
| histamine antagonist | 21 |
| histamine releasing agent | 1 |
| histological dye | 53 |
| hiv protease inhibitor | 13 |
| hiv-1 integrase inhibitor | 12 |
| hiv-1 maturation inhibitor | 1 |
| hiv-1 reverse transcriptase inhibitor | 25 |
| hiv-1 tat inhibitor | 1 |
| hormone | 4 |
| hormone agonist | 2 |
| hormone antagonist | 5 |
| hsp70 inducer | 1 |
| hsp90 inhibitor | 19 |
| human blood serum metabolite | 48 |
| human metabolite | 656 |
| human urinary metabolite | 99 |
| human xenobiotic metabolite | 141 |
| hyaluronan synthesis inhibitor | 2 |
| hyaluronic acid synthesis inhibitor | 1 |
| hydrogen acceptor | 1 |
| hydrogen donor | 1 |
| hyperglycemic agent | 1 |
| hypoglycemic agent | 67 |
| hypoxia-inducible factor pathway activator | 1 |
| immunogen | 1 |
| immunological adjuvant | 11 |
| immunomodulator | 27 |
| immunosuppressive agent | 54 |
| indicator | 5 |
| inhalation anaesthetic | 11 |
| inhibitor | 9 |
| insect attractant | 9 |
| insect growth regulator | 2 |
| insect repellent | 8 |
| insect sterilant | 4 |
| insecticide | 48 |
| insulin secretagogue | 5 |
| insulin-like growth factor receptor 1 antagonist | 2 |
| insulin-like growth factor-binding protein inhibitor | 1 |
| insulin-sensitizing drug | 4 |
| intercalator | 10 |
| interferon inducer | 2 |
| intravenous anaesthetic | 15 |
| ion transport inhibitor | 3 |
| ionophore | 9 |
| ip3 receptor antagonist | 2 |
| iron chelator | 12 |
| jacobaea metabolite | 1 |
| jasmonates | 2 |
| juvenile hormone mimic | 5 |
| k-atp channel agonist | 2 |
| kairomone | 1 |
| kappa-opioid receptor agonist | 9 |
| kappa-opioid receptor antagonist | 1 |
| keratolytic drug | 12 |
| kisspeptin receptor agonist | 1 |
| lachrymator | 5 |
| laxative | 10 |
| leprostatic drug | 6 |
| leukotriene antagonist | 9 |
| lewis acid | 5 |
| lewis base | 1 |
| lichen metabolite | 3 |
| ligand | 5 |
| lim kinase inhibitor | 1 |
| lipopolysaccharide biosynthesis inhibitor | 1 |
| lipoxygenase inhibitor | 12 |
| liver x receptor agonist | 1 |
| liver x receptor inverse agonist | 1 |
| local anaesthetic | 38 |
| loop diuretic | 5 |
| luciferin | 2 |
| lymphocyte function-associated antigen-1 antagonist | 1 |
| macronutrient | 3 |
| macrophage migration inhibitory factor inhibitor | 1 |
| maillard reaction product | 16 |
| maldi matrix material | 8 |
| mammalian metabolite | 31 |
| marine metabolite | 99 |
| marine xenobiotic metabolite | 41 |
| matrix metalloproteinase inhibitor | 7 |
| melanin synthesis inhibitor | 8 |
| melanin-concentrating hormone receptor antagonist | 1 |
| melatonin receptor agonist | 1 |
| melatonin receptor antagonist | 1 |
| membrane transport modulator | 1 |
| metabolite | 942 |
| metabotropic glutamate receptor agonist | 7 |
| metabotropic glutamate receptor antagonist | 4 |
| methionine aminopeptidase 2 inhibitor | 2 |
| micronutrient | 33 |
| microtubule-destabilising agent | 17 |
| microtubule-stabilising agent | 7 |
| miotic | 4 |
| mite growth regulator | 3 |
| mitochondrial cytochrome-bc1 complex inhibitor | 12 |
| mitochondrial nadh:ubiquinone reductase inhibitor | 9 |
| mitochondrial respiratory-chain inhibitor | 7 |
| mitogen | 7 |
| molluscicide | 8 |
| monolignol | 3 |
| mordant | 1 |
| mouse metabolite | 560 |
| mri contrast agent | 5 |
| mtor inhibitor | 13 |
| mtp inhibitor | 1 |
| mu-opioid receptor agonist | 27 |
| mu-opioid receptor antagonist | 6 |
| mucolytic | 8 |
| muscarinic agonist | 9 |
| muscarinic antagonist | 53 |
| muscle relaxant | 43 |
| mutagen | 83 |
| mycoestrogen | 1 |
| mycoplasma genitalium metabolite | 38 |
| mycotoxin | 31 |
| mydriatic agent | 2 |
| nasal decongestant | 8 |
| necroptosis inhibitor | 4 |
| nematicide | 26 |
| neonicotinoid insectide | 9 |
| nephroprotective agent | 11 |
| nephrotoxic agent | 10 |
| nephrotoxin | 12 |
| neurokinin-1 receptor agonist | 1 |
| neurokinin-1 receptor antagonist | 4 |
| neuromuscular agent | 8 |
| neuropeptide ff receptor agonist | 1 |
| neuropeptide ff receptor antagonist | 1 |
| neuropilin receptor antagonist | 1 |
| neuroprotective agent | 131 |
| neurotoxin | 53 |
| neurotransmitter | 17 |
| neurotransmitter agent | 6 |
| nf-kappab inhibitor | 17 |
| nicotinic acetylcholine receptor agonist | 14 |
| nicotinic antagonist | 17 |
| nitric oxide donor | 10 |
| nitrification inhibitor | 6 |
| nmda receptor agonist | 6 |
| nmda receptor antagonist | 31 |
| nmr chemical shift reference compound | 27 |
| nmr shift reagent | 1 |
| nmr solvent | 5 |
| non-narcotic analgesic | 98 |
| non-polar solvent | 21 |
| non-steroidal anti-inflammatory drug | 129 |
| nonionic surfactant | 6 |
| nonnucleoside hepatitis c virus polymerase inhibitor | 1 |
| nonstructural protein 5a inhibitor | 1 |
| nootropic agent | 9 |
| nucleophilic reagent | 3 |
| nucleoside antibiotic | 4 |
| nutraceutical | 48 |
| nutrient | 4 |
| odorant receptor agonist | 1 |
| odorant receptor antagonist | 1 |
| oneirogen | 6 |
| ophthalmology drug | 7 |
| opioid analgesic | 36 |
| opioid receptor agonist | 3 |
| oral contraceptive | 1 |
| orexin receptor antagonist | 1 |
| orphan drug | 13 |
| osmolyte | 5 |
| osmotic diuretic | 1 |
| osteogenesis regulator | 5 |
| oxidative phosphorylation inhibitor | 2 |
| oxidising agent | 18 |
| oxidized luciferins | 2 |
| oxytocic | 8 |
| p2y12 receptor antagonist | 5 |
| p2y2 receptor agonist | 1 |
| p450 inhibitor | 28 |
| p53 activator | 2 |
| papio hamadryas metabolite | 1 |
| par2 negative allosteric modulator | 1 |
| parasympatholytic | 13 |
| partial prostacyclin agonist | 1 |
| pediculicide | 2 |
| penicillium metabolite | 31 |
| peptide coupling reagent | 2 |
| peptidomimetic | 6 |
| peripheral nervous system drug | 22 |
| perk inhibitor | 1 |
| persistent organic pollutant | 15 |
| pesticide | 3 |
| pesticide synergist | 1 |
| phase-transfer catalyst | 3 |
| phenothiazine antipsychotic drug | 15 |
| phenoxy herbicide | 10 |
| pheromone | 26 |
| phosphoantigen | 6 |
| phosphodiesterase iv inhibitor | 5 |
| phospholipid biosynthesis inhibitor | 4 |
| photosensitizing agent | 21 |
| photosynthetic electron-transport chain inhibitor | 1 |
| photosystem-ii inhibitor | 4 |
| physical tracer | 1 |
| phytoalexin | 8 |
| phytoestrogen | 14 |
| phytogenic insecticide | 6 |
| phytotoxin | 15 |
| piezo1 agonist | 1 |
| piscicide | 3 |
| plant activator | 3 |
| plant growth regulator | 10 |
| plant growth retardant | 15 |
| plant growth stimulator | 3 |
| plant hormone | 10 |
| plant metabolite | 1,054 |
| plasticiser | 11 |
| platelet aggregation inhibitor | 62 |
| platelet glycoprotein-iib/iiia receptor antagonist | 2 |
| platelet-activating factor receptor agonist | 2 |
| poison | 13 |
| polar aprotic solvent | 17 |
| polar solvent | 2 |
| polymerisation monomer | 4 |
| potassium channel blocker | 16 |
| potassium channel modulator | 2 |
| potassium channel opener | 3 |
| potassium ionophore | 4 |
| ppar modulator | 1 |
| pparalpha agonist | 8 |
| pparbeta/delta agonist | 1 |
| ppargamma agonist | 5 |
| precocenes | 3 |
| pregnane x receptor agonist | 2 |
| pro-angiogenic agent | 8 |
| proacaricide | 2 |
| probe | 2 |
| prodrug | 140 |
| profungicide | 2 |
| progesterone receptor agonist | 2 |
| progesterone receptor modulator | 1 |
| progestin | 20 |
| progestogen | 1 |
| proherbicide | 6 |
| prohormone | 2 |
| proinsecticide | 2 |
| prostacyclin receptor agonist | 2 |
| prostaglandin antagonist | 4 |
| prostaglandin receptor agonist | 7 |
| prostaglandin receptor antagonist | 1 |
| prosthetic group | 4 |
| protease inhibitor | 9 |
| protease-activated receptor-1 antagonist | 1 |
| proteasome inhibitor | 11 |
| protective agent | 15 |
| protein denaturant | 2 |
| protein kinase a agonist | 1 |
| protein kinase agonist | 4 |
| protein kinase c agonist | 8 |
| protein kinase g agonist | 2 |
| protein kinase inhibitor | 13 |
| protein synthesis inhibitor | 26 |
| protein-sequencing agent | 1 |
| protic solvent | 18 |
| provitamin | 1 |
| provitamin a | 3 |
| provitamin b1 | 1 |
| psychotropic drug | 16 |
| purinergic receptor p2 antagonist | 2 |
| purinergic receptor p2x antagonist | 1 |
| pyrethroid ester acaricide | 8 |
| pyrethroid ester insecticide | 18 |
| pyrethroid ether insecticide | 1 |
| pyrimidine synthesis inhibitor | 3 |
| quinol oxidation site inhibitor | 1 |
| quinone outside inhibitor | 2 |
| quorum sensing inhibitor | 5 |
| radiation protective agent | 14 |
| radical scavenger | 68 |
| radioactive imaging agent | 3 |
| radioactive label | 1 |
| radioopaque medium | 23 |
| radiosensitizing agent | 17 |
| raising agent | 2 |
| rat metabolite | 43 |
| reaction intermediate | 1 |
| reactive oxygen species generator | 4 |
| reagent | 21 |
| receptor modulator | 4 |
| reducing agent | 10 |
| refrigerant | 24 |
| renal agent | 3 |
| retinoic acid receptor agonist | 2 |
| retinoic acid receptor alpha antagonist | 4 |
| retinoic acid receptor alpha/beta agonist | 2 |
| retinoic acid receptor antagonist | 1 |
| retinoic acid receptor beta agonist | 1 |
| retinoic acid receptor gamma agonist | 1 |
| retinoic acid receptor gamma antagonist | 1 |
| retinoid x receptor agonist | 2 |
| rhoa inhibitor | 1 |
| rhoc inhibitor | 1 |
| rodenticide | 8 |
| runx1 inhibitor | 1 |
| ryanodine receptor agonist | 7 |
| ryanodine receptor antagonist | 1 |
| ryanodine receptor modulator | 1 |
| s100 calcium-binding protein b inhibitor | 1 |
| saccharomyces cerevisiae metabolite | 165 |
| salt-inducible kinase 2 inhibitor | 1 |
| scabicide | 3 |
| schistosomicide drug | 6 |
| sclerotherapy agent | 1 |
| second generation antipsychotic | 14 |
| secreted frizzled-related protein 1 inhibitor | 1 |
| sedative | 56 |
| semiochemical | 3 |
| sensitiser | 11 |
| serca activator | 1 |
| serine protease inhibitor | 8 |
| serine proteinase inhibitor | 4 |
| serotonergic agonist | 41 |
| serotonergic antagonist | 70 |
| serotonergic drug | 5 |
| serotonin uptake inhibitor | 31 |
| sialyltransferase inhibitor | 1 |
| siderophore | 20 |
| sigma-2 receptor agonist | 1 |
| signalling molecule | 16 |
| sir2 inhibitor | 4 |
| skin lightening agent | 4 |
| smad3 inhibitor | 1 |
| smo receptor agonist | 3 |
| smo receptor antagonist | 3 |
| sodium channel blocker | 19 |
| sodium channel modulator | 1 |
| sodium-dependent pi-transporter inhibitor | 1 |
| sodium-glucose transport protein subtype 2 inhibitor | 3 |
| soluble guanylate cyclase activator | 7 |
| solvent | 23 |
| somatostatin receptor agonist | 3 |
| specialised pro-resolving mediator | 1 |
| spectrophotometric reagent | 1 |
| sphingosine-1-phosphate receptor 1 antagonist | 1 |
| sphingosine-1-phosphate receptor 2 antagonist | 1 |
| sphingosine-1-phosphate receptor 3 antagonist | 1 |
| sphingosine-1-phosphate receptor agonist | 4 |
| spin label | 5 |
| spin trapping reagent | 1 |
| stat3 inhibitor | 4 |
| steroid receptor coactivator stimulator | 1 |
| sterol biosynthesis inhibitor | 6 |
| sterol methyltransferase inhibitor | 1 |
| substance p receptor antagonist | 1 |
| sulfite ester acaricide | 1 |
| surfactant | 15 |
| survivin suppressant | 1 |
| sweetening agent | 20 |
| sympatholytic agent | 10 |
| sympathomimetic agent | 33 |
| synthetic auxin | 10 |
| synthetic oral contraceptive | 13 |
| t-cell proliferation inhibitor | 2 |
| t-type calcium channel blocker | 7 |
| tankyrase inhibitor | 1 |
| tau aggregation inhibitor | 2 |
| teratogenic agent | 37 |
| tetrazine acaricide | 1 |
| tgfbeta receptor antagonist | 3 |
| thromboxane a2 antagonist | 2 |
| thyroid hormone | 3 |
| tocolytic agent | 7 |
| tolerogen | 1 |
| topical anaesthetic | 5 |
| topoisomerase ii inhibitor | 3 |
| topoisomerase inhibitor | 1 |
| topoisomerase iv inhibitor | 8 |
| toxin | 36 |
| tracer | 1 |
| tranquilizing drug | 2 |
| triazine insecticide | 1 |
| tropomyosin-related kinase b receptor agonist | 4 |
| tropomyosin-related kinase b receptor antagonist | 2 |
| trp channel blocker | 4 |
| trpa1 channel agonist | 2 |
| trpm4 channel inhibitor | 1 |
| trpv channel modulator | 2 |
| trpv1 agonist | 3 |
| trpv4 agonist | 2 |
| trypanocidal drug | 21 |
| tubulin modulator | 8 |
| tumour antigen | 2 |
| two-colour indicator | 8 |
| tyrosine kinase inhibitor | 35 |
| udp-glucuronosyltransferase activator | 1 |
| ultrasound contrast agent | 3 |
| ultraviolet filter | 5 |
| uncoupling protein inhibitor | 3 |
| urea herbicide | 1 |
| uremic toxin | 7 |
| uricosuric drug | 6 |
| vascular endothelial growth factor receptor antagonist | 13 |
| vasoconstrictor agent | 32 |
| vasodilator agent | 116 |
| vasopressin receptor agonist | 2 |
| vasopressin receptor antagonist | 2 |
| vegf activator | 2 |
| venom | 1 |
| vesicant | 2 |
| vesicular glutamate transport inhibitor | 1 |
| vibriostatic agent | 1 |
| virulence factor | 4 |
| vitamin b1 antagonist | 1 |
| vitamin k antagonist | 3 |
| volatile oil component | 76 |
| voltage-dependent anion channel inhibitor | 1 |
| voltage-gated sodium channel blocker | 4 |
| vulnerary | 10 |
| water-soluble vitamin (role) | 2 |
| wnt signalling activator | 5 |
| wnt signalling inhibitor | 6 |
| xenobiotic | 249 |
| xenobiotic metabolite | 44 |
| xenoestrogen | 11 |