methotrexate has been researched along with Ph 1 Chromosome in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.85) | 18.7374 |
| 1990's | 5 (19.23) | 18.2507 |
| 2000's | 4 (15.38) | 29.6817 |
| 2010's | 10 (38.46) | 24.3611 |
| 2020's | 6 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| Advani, AS; Aldoss, I; Baer, MR; Bhave, RR; Erba, HP; Fang, M; Harvey, RC; Klisovic, RB; Litzow, MR; Moseley, A; O'Dwyer, KM; Othus, M; Park, JH; Sharon, E; Stock, W; Stone, RM; Wieduwilt, MJ; Willman, CL; Wood, BL | 1 |
| Alvarado, Y; Ferrajoli, A; Garcia-Manero, G; Garris, R; Huang, X; Jabbour, E; Jain, N; Kadia, TM; Kantarjian, H; Konopleva, M; Macaron, W; Patel, KP; Ravandi, F; Short, NJ; Thompson, PA; Yilmaz, M | 1 |
| Chen, C; Li, X; Qi, J; Yongjing, W | 1 |
| Hidaka, Y; Kurata, T; Matsuoka, D; Morita, D; Morota, H; Nakazawa, Y; Natsume, T; Okura, E; Saito, S; Sakashita, K; Shigemura, T; Tanaka, M; Uchida, E; Watanabe, T | 1 |
| Burke, MJ; Egelund, TA; Katzenstein, HM; Liberio, N; Ng, JS; Pommert, L; Siver, MJ | 1 |
| Beaumont, AL; Suner, L | 1 |
| Fruman, DA; Khaw, A; Konopleva, M; Lee, JS; Lu, M; Lui, B; Mallya, S; Müschen, M; Nguyen, D; Pandori, W; Vo, TT | 1 |
| Adams, G; Apperley, JF; Brannigan, E; Davies, F; Fernando, F; Innes, AJ; Marchesi, JR; Mullish, BH; Pavlů, J | 1 |
| Burger, JA; Challagundla, P; Champlin, RE; Cortes, JE; Estrov, Z; Faderl, S; Ferrajoli, A; Garris, R; Huang, X; Jorgensen, JL; Kantarjian, HM; Kebriaei, P; Luthra, R; O'Brien, S; Ravandi, F; Thomas, DA; Wang, SA; Wen, S | 1 |
| Hatta, Y | 1 |
| Aspillaga, A; Cabrera, ME; Calderón, S; Guerra, C; Lois, V; Molina, J; Muñoz, L; Pilleux, L; Pizarro, A; Puga, B; Rojas, C; Rojas, H; Vergara, CG | 1 |
| Abrahamsson, J; Asberg, A; Birgens, H; Frandsen, T; Griškevičius, L; Hallböök, H; Helt, LR; Heyman, M; Jónsson, ÓG; Klausen, TW; Palk, K; Pruunsild, K; Quist-Paulsen, P; Schmiegelow, K; Toft, N; Vaitkeviciene, G; Vettenranta, K | 1 |
| Bae, SH; Chi, HS; Eom, HS; Hyun, MS; Jang, DY; Joo, YD; Jung, CW; Kim, DY; Kim, H; Kim, HJ; Kim, I; Kim, MK; Lee, GW; Lee, JH; Lee, KH; Lee, SM; Lee, WS; Lim, SN; Moon, JH; Park, S; Ryoo, HM; Shin, HJ; Sohn, SK; Won, JH; Yang, DH; Yun, SC | 1 |
| Burger, JA; Champlin, R; Cortes, JE; Estrov, Z; Faderl, S; Ferrajoli, A; Garcia-Manero, G; Garris, R; Huang, X; Jabbour, E; Kantarjian, HM; Kebriaei, P; McCue, DA; O'Brien, SM; Ravandi, F; Rytting, ME; Thomas, DM; Verstovsek, S; Wierda, WG | 1 |
| Goulden, N; Hough, R; Mitchell, C; Moorman, A; Rowntree, C; Vora, A; Wade, R | 1 |
| Cortes, JE; Garcia-Manero, G; Garris, R; Issa, GC; Jabbour, E; Kantarjian, H; Luthra, R; O'Brien, SM; Patel, K; Ravandi, F; Sasaki, K; Short, NJ; Thomas, D | 1 |
| Ahmed, N; Cang, S; Liu, D; Mathews, T; Primanneni, S; Seiter, K; Tan, J | 1 |
| Abdelhaleem, M; Abla, O; Gassas, A; Grant, R; Stevens, R | 1 |
| Adamczyk-Cioch, M; Dmoszyńska, A; Haus, O; Hołowiecki, J; Jakubas, B; Jedrzejczak, WW; Konopka, L; Kuliczkowski, K; Mazur, G; Nowak, K; Paluszewska, M; Pałynyczko, G; Pluta, A; Robak, T; Skotnicki, A; Wawrzyniak, E; Wierzbowska, A; Wrzesień-Kuś, A; Zwolińska, M | 1 |
| Babacan, E; Bökesoy, I; Cavdar, AO; Gözdaşoğlu, S; Pamĭr, A; Sunguroğlu, A; Tanindi, S; Türker, A; Unal, E; Yavuz, G | 1 |
| Bradstock, K; Brisco, J; Enno, A; Hughes, E; McCaul, K; Morley, AA; Neoh, SH; Sykes, PJ; Szer, J | 1 |
| Aguayo, A; Cortes, J; Kantarjian, H; Keating, M; Pierce, S; Thomas, D | 1 |
| Garcia-Manero, G; Kantarjian, HM | 1 |
| Bailly, F; Caillot, D; Carli, PM; Chavanet, P; Devilliers, E; Guy, H; Mugneret, F; Petrella, T; Solary, E; Waldner, A | 1 |
| Sommelet, D | 1 |
| Arthur, D; Haake, R; Hurd, D; Kersey, J; Kim, T; McGlave, P; Miller, W; Ramsay, N; Vercellotti, G; Weisdorf, D | 1 |
4 review(s) available for methotrexate and Ph 1 Chromosome
| Article | Year |
|---|---|
[Acute lymphoblastic leukemia].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cyclophosphamide; Dasatinib; Daunorubicin; Doxorubicin; Enzyme Inhibitors; Humans; Imatinib Mesylate; Methotrexate; Middle Aged; Philadelphia Chromosome; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Protein-Tyrosine Kinases; Pyrimidines; Thiazoles; Young Adult | 2014 |
t(3;9;22) 3-way chromosome translocation in chronic myeloid leukemia is associated with poor prognosis.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Blast Crisis; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 9; Cyclophosphamide; Dasatinib; Dexamethasone; Disease Progression; Doxorubicin; Drug Resistance, Neoplasm; Fatal Outcome; Humans; Imatinib Mesylate; Karyotyping; Leukemia, Myeloid, Chronic-Phase; Male; Methotrexate; Middle Aged; Philadelphia Chromosome; Piperazines; Prognosis; Protein Kinase Inhibitors; Pyrimidines; Rituximab; Thiazoles; Translocation, Genetic; Vincristine | 2009 |
The hyper-CVAD regimen in adult acute lymphocytic leukemia.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Central Nervous System Neoplasms; Child; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dexamethasone; Doxorubicin; Drug Administration Schedule; Granulocyte Colony-Stimulating Factor; Humans; Immunization, Passive; Immunophenotyping; Infusions, Intravenous; Injections, Spinal; Karyotyping; Mercaptopurine; Methotrexate; Middle Aged; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Risk; Rituximab; Survival Analysis; Texas; Treatment Outcome; Vincristine | 2000 |
[Recent advances in oncology. Acute lymphoblastic leukemia in children].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Chromosome Deletion; Cytogenetics; Humans; Methotrexate; Philadelphia Chromosome; Ploidies; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Translocation, Genetic | 1991 |
7 trial(s) available for methotrexate and Ph 1 Chromosome
| Article | Year |
|---|---|
SWOG 1318: A Phase II Trial of Blinatumomab Followed by POMP Maintenance in Older Patients With Newly Diagnosed Philadelphia Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia.
Topics: Aged; Antibodies, Bispecific; Antineoplastic Combined Chemotherapy Protocols; Humans; Lymphoma, B-Cell; Methotrexate; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2022 |
Hyper-CVAD and sequential blinatumomab for newly diagnosed Philadelphia chromosome-negative B-cell acute lymphocytic leukaemia: a single-arm, single-centre, phase 2 trial.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vincristine | 2022 |
Long-term follow-up of imatinib plus combination chemotherapy in patients with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Imatinib Mesylate; Induction Chemotherapy; Male; Methotrexate; Middle Aged; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Recurrence; Remission Induction; Survival Analysis; Transplantation, Homologous; Vincristine | 2015 |
Long-term follow-up of a phase 2 study of chemotherapy plus dasatinib for the initial treatment of patients with Philadelphia chromosome-positive acute lymphoblastic leukemia.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dasatinib; Dexamethasone; Doxorubicin; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Neoplasm, Residual; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Analysis; Treatment Outcome; Vincristine; Young Adult | 2015 |
Efficacy and toxicity of a paediatric protocol in teenagers and young adults with Philadelphia chromosome negative acute lymphoblastic leukaemia: results from UKALL 2003.
Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Daunorubicin; Dexamethasone; Female; Humans; Male; Mercaptopurine; Methotrexate; Neoplasm, Residual; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Assessment; Survival Analysis; Treatment Outcome; Vincristine; Young Adult | 2016 |
Relationship between minimal residual disease and outcome in adult acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Bone Marrow Transplantation; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Neoplasm; Etoposide; Gene Rearrangement, B-Lymphocyte, Heavy Chain; Humans; Mercaptopurine; Methotrexate; Middle Aged; Neoplasm, Residual; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Survival Analysis; Treatment Outcome; Vincristine | 1996 |
Combination therapy with methotrexate, vincristine, polyethylene-glycol conjugated-asparaginase, and prednisone in the treatment of patients with refractory or recurrent acute lymphoblastic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Drug Administration Schedule; Enzymes, Immobilized; Female; Humans; L-Lactate Dehydrogenase; Male; Methotrexate; Middle Aged; Philadelphia Chromosome; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Remission Induction; Treatment Outcome; Vincristine | 1999 |
15 other study(ies) available for methotrexate and Ph 1 Chromosome
| Article | Year |
|---|---|
Acute kidney injury and delayed methotrexate clearance in an adult patient with Philadelphia chromosome-positive acute lymphoblastic leukaemia treated with imatinib.
Topics: Acute Kidney Injury; Adult; Female; Humans; Imatinib Mesylate; Methotrexate; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2023 |
Delayed methotrexate clearance and acute kidney injury after high-dose methotrexate chemotherapy concurrent with dasatinib in a patient with relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia: A case report.
Topics: Acute Kidney Injury; Dasatinib; Humans; Methotrexate; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors | 2020 |
Concurrent Imatinib Dosing With High-dose Methotrexate Leads to Acute Kidney Injury and Delayed Methotrexate Clearance in Pediatric Patients With Philadelphia Chromosome-positive B-Cell Acute Lymphoblastic Leukemia.
Topics: Acute Kidney Injury; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Imatinib Mesylate; Leukemia, B-Cell; Male; Methotrexate; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Young Adult | 2021 |
Drug-induced aseptic meningitis in a Ph+ ALL patient with meningeal involvement.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Meningitis, Aseptic; Methotrexate; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2020 |
mTORC1 Inhibition Induces Resistance to Methotrexate and 6-Mercaptopurine in Ph
Topics: Animals; Antimetabolites, Antineoplastic; Cell Cycle; Cell Line, Tumor; Disease Models, Animal; DNA Damage; Drug Resistance, Neoplasm; Female; Humans; Male; Mechanistic Target of Rapamycin Complex 1; Mercaptopurine; Methotrexate; Mice; Mice, Knockout; Models, Biological; Philadelphia Chromosome; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Xenograft Model Antitumor Assays | 2017 |
Faecal microbiota transplant: a novel biological approach to extensively drug-resistant organism-related non-relapse mortality.
Topics: Allografts; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bacteria; Daunorubicin; Drug Resistance, Bacterial; Fatal Outcome; Fecal Microbiota Transplantation; Feces; Hematopoietic Stem Cell Transplantation; Humans; Male; Methotrexate; Middle Aged; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Vincristine | 2017 |
Detection of MRD may predict the outcome of patients with Philadelphia chromosome-positive ALL treated with tyrosine kinase inhibitors plus chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cyclophosphamide; Cytarabine; Dasatinib; Dexamethasone; Doxorubicin; Female; Flow Cytometry; Follow-Up Studies; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Immunoglobulin Heavy Chains; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm, Residual; Philadelphia Chromosome; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Pyrimidines; Real-Time Polymerase Chain Reaction; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Thiazoles; Vincristine; Young Adult | 2013 |
[Adolescent and young adult Philadelphia negative B cell acute lymphoblastic leukemia: results of the Chilean protocol LLA 15-30].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cohort Studies; Dexamethasone; Female; Humans; Male; Methotrexate; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Prospective Studies; Treatment Outcome; Vincristine; Young Adult | 2014 |
Toxicity profile and treatment delays in NOPHO ALL2008-comparing adults and children with Philadelphia chromosome-negative acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Female; Humans; Infant; Male; Methotrexate; Middle Aged; Osteonecrosis; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Remission Induction; Thrombosis; Treatment Outcome; Vincristine | 2016 |
Impact of complete molecular response on survival in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Female; Follow-Up Studies; Fusion Proteins, bcr-abl; Humans; Infant; Male; Methotrexate; Neoplasm, Residual; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Rate; Vincristine | 2016 |
bcr-abl-positive T-cell acute lymphoblastic leukemia associated with parvovirus B19 infection.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Cerebral Hemorrhage; Combined Modality Therapy; Disseminated Intravascular Coagulation; Fatal Outcome; Fusion Proteins, bcr-abl; Genes, abl; Hematopoietic Stem Cell Transplantation; Humans; Leukemia-Lymphoma, Adult T-Cell; Male; Methotrexate; Multiple Organ Failure; Neoplasm Proteins; Pancytopenia; Parvoviridae Infections; Parvovirus B19, Human; Philadelphia Chromosome; Pneumonia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Preleukemia; Shock, Septic; Staphylococcal Infections; Vincristine | 2006 |
Outcome of treatment in adults with Philadelphia chromosome-positive and/or BCR-ABL--positive acute lymphoblastic leukemia-retrospective analysis of Polish Adult Leukemia Group (PALG).
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Fusion Proteins, bcr-abl; Hematopoietic Stem Cell Transplantation; Humans; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mercaptopurine; Methotrexate; Middle Aged; Philadelphia Chromosome; Poland; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Retrospective Studies; Treatment Outcome | 2006 |
Orbito-ocular granulocytic sarcoma (OOGS) and acute myeloblastic leukemia (AML) with duplication of Philadelphia chromosome.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cytarabine; Dexamethasone; Doxorubicin; Etoposide; Eye Neoplasms; Humans; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Multigene Family; Neoplasms, Multiple Primary; Orbital Neoplasms; Philadelphia Chromosome; Thioguanine | 1993 |
Bone marrow necrosis and human parvovirus associated infection preceding an Ph1+ acute lymphoblastic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cyclophosphamide; Daunorubicin; Erythema Infectiosum; Female; Humans; Karyotyping; Methotrexate; Pancytopenia; Parvovirus B19, Human; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Steroids; Vincristine | 1992 |
Therapy of chronic myelogenous leukemia with allogeneic bone marrow transplantation.
Topics: Antigens, Surface; Antilymphocyte Serum; Bone Marrow Transplantation; Cyclophosphamide; Graft vs Host Disease; Histocompatibility Testing; Humans; Immunosuppression Therapy; Leukemia, Myeloid; Methotrexate; Philadelphia Chromosome; Prednisone; Probability; T-Lymphocytes; Time Factors; Whole-Body Irradiation | 1987 |