busulfan has been researched along with Ph 1 Chromosome in 36 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eighty-three patients with various chronic myeloproliferative disorders [polycythemia vera (PV), essential thrombocytosis (ET), idiopathic myelofibrosis (IMF)] were analyzed for the occurrence of acute myeloid leukemia (AML) and myelodysplasia (MDS) during treatment with hydroxyurea (HU) alone or HU following treatment with busulphan (BU)." | 7.72 | Acute leukemia and myelodysplasia in patients with a Philadelphia chromosome negative chronic myeloproliferative disorder treated with hydroxyurea alone or with hydroxyurea after busulphan. ( Hasselbalch, HC; Nielsen, I, 2003) |
| "Eighty-three patients with various chronic myeloproliferative disorders [polycythemia vera (PV), essential thrombocytosis (ET), idiopathic myelofibrosis (IMF)] were analyzed for the occurrence of acute myeloid leukemia (AML) and myelodysplasia (MDS) during treatment with hydroxyurea (HU) alone or HU following treatment with busulphan (BU)." | 3.72 | Acute leukemia and myelodysplasia in patients with a Philadelphia chromosome negative chronic myeloproliferative disorder treated with hydroxyurea alone or with hydroxyurea after busulphan. ( Hasselbalch, HC; Nielsen, I, 2003) |
| "One of the MPDs, chronic myeloid leukemia (CML), has the distinct cytogenetic abnormality of the Philadelphia chromosome." | 2.42 | Treatment paradigms in the management of myeloproliferative disorders. ( Fruchtman, SM, 2004) |
| "Treatment with busulfan was stopped in March 1993 due to bone marrow suppression." | 1.32 | Long-term cytogenetic remission with ubenimex monotherapy in a case of chronic myeloid leukemia. ( Fujimaki, K; Ishigatsubo, Y; Kanamori, H; Koharazawa, H; Taguchi, J; Takabayashi, M; Takasaki, H; Yamaji, S, 2004) |
| "We report a 44-yr-old female with Philadelphia chromosome positive chronic myeloid leukemia who was initially treated with busulfan, and clinical remission has been achieved." | 1.31 | Busulfan-induced loss of Ph chromosome in chronic myeloid leukemia. ( Colovic, M; Krtolica, K; Radojkovic, M; Ristic, S; Todoric, B, 2001) |
| "The frequency of chromosome aberrations and sister chromatid exchange (SCE) increased dose dependently." | 1.27 | Induction of sister chromatid exchanges and chromosomal aberrations by busulfan in Philadelphia chromosome-positive chronic myeloid leukemia and normal bone marrow. ( Becher, R; Prescher, G, 1988) |
| "Busulfan was given over 4 weeks resulting in a remission of 13 years duration." | 1.27 | [24-year survival in chronic myeloid leukemia]. ( Hehlmann, R; Müller, L, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (50.00) | 18.7374 |
| 1990's | 5 (13.89) | 18.2507 |
| 2000's | 9 (25.00) | 29.6817 |
| 2010's | 4 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Douglas, G | 1 |
| Harrison, C | 1 |
| Forsyth, C | 1 |
| Bennett, M | 1 |
| Stevenson, W | 1 |
| Hounsell, J | 1 |
| Ratnasingam, S | 1 |
| Ritchie, D | 1 |
| Ross, DM | 1 |
| Grigg, A | 1 |
| Deininger, MW | 1 |
| Yamamoto, M | 1 |
| Kuroda, J | 1 |
| Uchiyama, H | 1 |
| Kobayashi, T | 2 |
| Tsutsumi, Y | 1 |
| Ohshiro, M | 1 |
| Sasaki, N | 1 |
| Shimura, Y | 1 |
| Mizutani, S | 1 |
| Matsumoto, Y | 1 |
| Shimazaki, C | 2 |
| Horiike, S | 1 |
| Taniwaki, M | 1 |
| Marks, DI | 1 |
| Wang, T | 1 |
| Pérez, WS | 1 |
| Antin, JH | 1 |
| Copelan, E | 1 |
| Gale, RP | 1 |
| George, B | 1 |
| Gupta, V | 1 |
| Halter, J | 1 |
| Khoury, HJ | 1 |
| Klumpp, TR | 1 |
| Lazarus, HM | 1 |
| Lewis, VA | 1 |
| McCarthy, P | 1 |
| Rizzieri, DA | 1 |
| Sabloff, M | 1 |
| Szer, J | 1 |
| Tallman, MS | 1 |
| Weisdorf, DJ | 1 |
| Ding, J | 1 |
| Bao, W | 1 |
| Wang, J | 1 |
| Zhao, G | 1 |
| Chen, J | 1 |
| Song, H | 1 |
| Nielsen, I | 1 |
| Hasselbalch, HC | 1 |
| FREI, E | 1 |
| TJIO, JH | 1 |
| WHANG, J | 1 |
| CARBONE, PP | 1 |
| TEPLITZ, RL | 1 |
| ROSEN, RB | 1 |
| TEPLITZ, MR | 1 |
| HAMPEL, KE | 1 |
| DOUGAN, L | 1 |
| WOODLIFF, HJ | 1 |
| Fruchtman, SM | 1 |
| Kanamori, H | 1 |
| Takasaki, H | 1 |
| Takabayashi, M | 1 |
| Yamaji, S | 1 |
| Koharazawa, H | 1 |
| Fujimaki, K | 1 |
| Taguchi, J | 1 |
| Ishigatsubo, Y | 1 |
| Krejci, M | 1 |
| Mayer, J | 1 |
| Doubek, M | 1 |
| Brychtova, Y | 1 |
| Pospisil, Z | 1 |
| Racil, Z | 1 |
| Dvorakova, D | 1 |
| Lengerova, M | 1 |
| Horky, O | 1 |
| Koristek, Z | 1 |
| Dolezal, T | 1 |
| Vorlicek, J | 1 |
| Avalos, BR | 1 |
| Klein, JL | 1 |
| Kapoor, N | 1 |
| Copelan, EA | 1 |
| Ohnishi, K | 1 |
| Tomonaga, M | 1 |
| Kamada, N | 1 |
| Onozawa, K | 1 |
| Kuramoto, A | 1 |
| Dohy, H | 1 |
| Mizoguchi, H | 1 |
| Miyawaki, S | 1 |
| Tsubaki, K | 1 |
| Miura, Y | 1 |
| Omine, M | 1 |
| Naoe, T | 1 |
| Ohshima, T | 1 |
| Hirashima, K | 1 |
| Ohtake, S | 1 |
| Takahashi, I | 1 |
| Morishima, Y | 1 |
| Naito, K | 1 |
| Asou, N | 1 |
| Tanimoto, M | 1 |
| Sakuma, A | 1 |
| Ohno, R | 1 |
| Guilhot, F | 1 |
| McBride, NC | 1 |
| Cavenagh, JD | 1 |
| Newland, AC | 1 |
| Lillington, DM | 1 |
| Murrell, C | 1 |
| Kelsey, SM | 1 |
| Hernández-Boluda, JC | 1 |
| Carreras, E | 1 |
| Cervantes, F | 2 |
| Marín, P | 1 |
| Arellano-Rodrigo, E | 1 |
| Rovira, M | 1 |
| Solé, F | 1 |
| Lloveras, E | 1 |
| Espinet, B | 1 |
| Ocejo, A | 1 |
| Montserrat, E | 1 |
| Radojkovic, M | 1 |
| Ristic, S | 1 |
| Colovic, M | 1 |
| Todoric, B | 1 |
| Krtolica, K | 1 |
| Birnie, GD | 1 |
| MacKenzie, ED | 1 |
| Goyns, MH | 1 |
| Pollock, A | 1 |
| Bergsagel, DE | 2 |
| Messner, H | 1 |
| Iurlo, A | 1 |
| Foa, P | 1 |
| Maiolo, AT | 1 |
| Polli, EE | 1 |
| Ostendorf, P | 1 |
| Ehninger, G | 1 |
| Schmidt, H | 1 |
| Haen, M | 1 |
| Link, H | 1 |
| Schüch, K | 1 |
| Müller, C | 1 |
| Wernet, P | 1 |
| Dopfer, H | 1 |
| Klingebiel, T | 1 |
| Becher, R | 1 |
| Prescher, G | 1 |
| Hehlmann, R | 3 |
| Anger, B | 2 |
| Messerer, D | 1 |
| Zankovich, R | 1 |
| Bergmann, L | 2 |
| Kolb, HJ | 2 |
| Meyer, P | 1 |
| Essers, U | 1 |
| Queisser, U | 1 |
| Vaupel, H | 1 |
| Heimpel, H | 1 |
| Hossfeld, DK | 1 |
| Köpcke, W | 1 |
| Löffler, H | 1 |
| Pralle, H | 1 |
| Queisser, W | 1 |
| Rozman, C | 1 |
| Ballesta, F | 1 |
| Milá, M | 1 |
| Avilés, A | 1 |
| Ibarrola, JL | 1 |
| Sigler, L | 1 |
| Pizzuto, J | 1 |
| Müller, L | 1 |
| Ogura, H | 1 |
| Shirafuji, N | 1 |
| Kumakawa, T | 1 |
| Matsuda, S | 1 |
| Horiuchi, N | 1 |
| Kodo, H | 1 |
| Fujii, H | 1 |
| Asano, S | 1 |
| Miwa, S | 1 |
| Shinohara, T | 1 |
| Griffin, JD | 1 |
| Lingg, G | 1 |
| Schmalzl, F | 1 |
| Breton-Gorius, J | 1 |
| Tabilio, A | 1 |
| Schaefer, HE | 1 |
| Geissler, D | 1 |
| Schweiger, M | 1 |
| Kirchmair, W | 1 |
| Kantarjian, HM | 1 |
| Smith, TL | 1 |
| McCredie, KB | 1 |
| Keating, MJ | 1 |
| Walters, RS | 1 |
| Talpaz, M | 1 |
| Hester, JP | 1 |
| Bligham, G | 1 |
| Gehan, E | 1 |
| Freireich, EJ | 1 |
| Van de Pette, JE | 1 |
| Prochazka, AV | 1 |
| Pearson, TC | 1 |
| Singh, AK | 1 |
| Dickson, ER | 1 |
| Wetherley-Mein, G | 1 |
3 reviews available for busulfan and Ph 1 Chromosome
| Article | Year |
|---|---|
Treatment paradigms in the management of myeloproliferative disorders.
Topics: Antineoplastic Agents, Alkylating; Busulfan; Chlorambucil; Hydroxyurea; Interferon-alpha; Leukemia, | 2004 |
Hydroxyurea versus busulphan for chronic myeloid leukaemia: an individual patient data meta-analysis of three randomized trials. Chronic myeloid leukemia trialists' collaborative group.
Topics: Antineoplastic Agents; Busulfan; Humans; Hydroxyurea; Leukemia, Myelogenous, Chronic, BCR-ABL Positi | 2000 |
Management of chronic myelogenous leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Hematopoiesis | 1986 |
5 trials available for busulfan and Ph 1 Chromosome
| Article | Year |
|---|---|
Allogeneic bone marrow transplantation following busulfan and 90 mg/kg of cyclophosphamide.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Combin | 1993 |
A long term follow-up of a randomized trial comparing interferon-alpha with busulfan for chronic myelogenous leukemia. The Kouseisho Leukemia Study Group.
Topics: Adult; Aged; Busulfan; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Interferon-a | 1998 |
Autologous transplantation with Philadelphia-negative progenitor cells for patients with chronic myeloid leukaemia (CML) failing to attain a cytogenetic response to alpha interferon.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality Therapy; Cyclopho | 2000 |
[Chemotherapy of chronic myelocytic leukemia. Status of the German Multicenter Study on busulfan versus hydroxyurea versus alpha interferon, October 1897].
Topics: Busulfan; Clinical Trials as Topic; Germany, West; Humans; Hydroxyurea; Interferon Type I; Leukemia, | 1988 |
[Prospective controlled study of therapy of chronic myeloid leukemia (CML)].
Topics: Adult; Aged; Busulfan; Clinical Trials as Topic; Humans; Hydroxyurea; Interferon Type I; Leukemia, M | 1987 |
28 other studies available for busulfan and Ph 1 Chromosome
| Article | Year |
|---|---|
Busulfan is effective second-line therapy for older patients with Philadelphia-negative myeloproliferative neoplasms intolerant of or unresponsive to hydroxyurea.
Topics: Antineoplastic Agents, Alkylating; Busulfan; Drug Resistance, Neoplasm; Drug Tolerance; Female; Foll | 2017 |
Chronic myeloid leukemia: an historical perspective.
Topics: Antineoplastic Agents; Busulfan; History, 19th Century; History, 20th Century; Humans; Leukemia, Mye | 2008 |
Allogenic bone marrow transplantation with fludarabine/busulfan16 conditioning regimen and dasatinib maintenance therapy for elderly Philadelphia-positive acute/advanced leukemia patients.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Bu | 2010 |
The outcome of full-intensity and reduced-intensity conditioning matched sibling or unrelated donor transplantation in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia in first and second complete remission.
Topics: Adolescent; Adult; Aged; Busulfan; Disease-Free Survival; Female; Graft vs Host Disease; Hematopoies | 2010 |
Effect of splenectomy on pancytopenia after a peripheral blood stem cell transplantation.
Topics: Adult; Busulfan; Cyclophosphamide; Dexamethasone; Female; Graft Survival; Graft vs Host Disease; Hem | 2011 |
Acute leukemia and myelodysplasia in patients with a Philadelphia chromosome negative chronic myeloproliferative disorder treated with hydroxyurea alone or with hydroxyurea after busulphan.
Topics: Acute Disease; Alkylating Agents; Busulfan; Chronic Disease; Drug Therapy, Combination; Female; Huma | 2003 |
STUDIES OF THE PHILADELPHIA CHROMOSOME IN PATIENTS WITH CHRONIC MYELOGENOUS LEUKEMIA.
Topics: Alkaline Phosphatase; Antineoplastic Agents; Bone Marrow Examination; Busulfan; Cell Division; Chrom | 1964 |
GRANULOCYTIC LEUKAEMIA, PHILADELPHIA CHROMOSOME, AND LEUCOCYTE ALKALINE PHOSPHATASE.
Topics: Alkaline Phosphatase; Bone Marrow Examination; Busulfan; Chromosome Aberrations; Chromosome Disorder | 1964 |
[DIPLO-PH 1-CHROMOSOME IN MYELOID LEUKEMIA].
Topics: Busulfan; Chromosomes; Drug Therapy; Humans; Leukemia; Leukemia, Myeloid; Osteochondritis; Philadelp | 1964 |
PRESENCE OF TWO PH-1 CHROMOSOMES IN CELLS FROM A PATIENT WITH CHRONIC GRANULOCYTIC LEUKAEMIA.
Topics: Bone Marrow Examination; Busulfan; Chromosome Aberrations; Drug Therapy; Humans; Leukemia; Leukemia, | 1965 |
Long-term cytogenetic remission with ubenimex monotherapy in a case of chronic myeloid leukemia.
Topics: Aged; Bone Marrow Cells; Busulfan; Humans; Immunologic Factors; Leucine; Leukemia, Myelogenous, Chro | 2004 |
Clinical outcomes and direct hospital costs of reduced-intensity allogeneic transplantation in chronic myeloid leukemia.
Topics: Adolescent; Adult; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Busulfan; C | 2006 |
[Interferon-alpha in the treatment of chronic myeloid leukemia].
Topics: Adult; Age Factors; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Age | 1999 |
Collection of Philadelphia-negative stem cells using recombinant human granulocyte colony-stimulating factor in chronic myeloid leukemia patients treated with alpha-interferon.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Blood Component | 2002 |
Busulfan-induced loss of Ph chromosome in chronic myeloid leukemia.
Topics: Adult; Antineoplastic Agents, Alkylating; Bone Marrow; Busulfan; DNA, Neoplasm; Female; Genes, abl; | 2001 |
Sequestration of Philadelphia chromosome-positive cells in the bone marrow of a chronic myeloid leukemia patient in very prolonged remission.
Topics: Bone Marrow; Busulfan; Female; Follow-Up Studies; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Po | 1990 |
The maintenance of busulphan-induced remissions in chronic granulocytic leukaemia with recombinant interferon alpha-2b.
Topics: Adult; Aged; Bone Marrow Transplantation; Busulfan; Female; Humans; Interferon alpha-2; Interferon T | 1990 |
Chronic myelogenous leukemia following radiation therapy for testicular seminoma.
Topics: Adult; Busulfan; Combined Modality Therapy; Dysgerminoma; Humans; Leukemia, Myelogenous, Chronic, BC | 1989 |
[Bone marrow transplantation in chronic myeloid leukemia. Influence of gnotobiotic measures, especially antiviral prophylaxis].
Topics: Acyclovir; Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclos | 1986 |
Induction of sister chromatid exchanges and chromosomal aberrations by busulfan in Philadelphia chromosome-positive chronic myeloid leukemia and normal bone marrow.
Topics: Adolescent; Adult; Bone Marrow; Busulfan; Cell Division; Chromosome Aberrations; Female; Humans; Leu | 1988 |
Interferon alfa-2b in the management of chronic granulocytic leukemia.
Topics: Adult; Aged; Busulfan; Female; Humans; Interferon Type I; Leukemia, Myeloid; Leukocyte Count; Male; | 1988 |
[Cytogenetic and therapeutic results of a protocol including splenectomy and intensive polychemotherapy in Ph'-positive chronic myeloid leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Clone Cells; Combined Modality Therapy; Cy | 1986 |
[Early splenectomy in chronic granulocytic leukemia. 15 years' experience].
Topics: Adult; Blast Crisis; Busulfan; Combined Modality Therapy; Follow-Up Studies; Humans; Leukemia, Myelo | 1986 |
[24-year survival in chronic myeloid leukemia].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Drug Administration Schedule; Female | 1987 |
[Two busulfan-resistant cases of CML (chronic myelogenous leukemia) with good response to alpha-interferon treatment].
Topics: Adult; Busulfan; Drug Resistance; Female; Humans; Interferon Type I; Leukemia, Myeloid; Male; Middle | 1987 |
Megakaryoblastic micromegakaryocytic crisis in chronic myeloid leukemia.
Topics: Bone Marrow Cells; Busulfan; Cell Transformation, Neoplastic; Female; Humans; Karyotyping; Leukemia, | 1985 |
Chronic myelogenous leukemia: a multivariate analysis of the associations of patient characteristics and therapy with survival.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Basophils; Blood Cell Coun | 1985 |
Primary thrombocythaemia treated with busulphan.
Topics: Adult; Aged; Blood Cell Count; Bone Marrow; Busulfan; Female; Humans; Male; Middle Aged; Philadelphi | 1986 |