cytarabine has been researched along with Ph 1 Chromosome in 55 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (7.27) | 18.7374 |
| 1990's | 17 (30.91) | 18.2507 |
| 2000's | 20 (36.36) | 29.6817 |
| 2010's | 12 (21.82) | 24.3611 |
| 2020's | 2 (3.64) | 2.80 |
| Authors | Studies |
|---|---|
| Beaumont, AL; Suner, L | 1 |
| Hu, BF; Shen, SH; Wang, GL; Wang, J | 1 |
| Alexander, PM; Caudell, DL; Kucera, GL; Pardee, TS; Pladna, KM | 1 |
| Chen, B; Chen, D; Guan, C; Peng, M; Shao, X; Xie, P; Xu, P; Yuan, C | 1 |
| Burger, JA; Challagundla, P; Champlin, RE; Cortes, JE; Estrov, Z; Faderl, S; Ferrajoli, A; Garris, R; Huang, X; Jorgensen, JL; Kantarjian, HM; Kebriaei, P; Luthra, R; O'Brien, S; Ravandi, F; Thomas, DA; Wang, SA; Wen, S | 1 |
| Akhtari, M; Armitage, JO; Bhatt, VR; Bociek, RG; Dave, BJ; Kessinger, A; Sanger, WG; Sanmann, JN; Yuan, J | 1 |
| Jiao, W; Li, X; Liu, L; Qu, Q; Wu, D; Zhang, Y | 1 |
| Bae, SH; Chi, HS; Eom, HS; Hyun, MS; Jang, DY; Joo, YD; Jung, CW; Kim, DY; Kim, H; Kim, HJ; Kim, I; Kim, MK; Lee, GW; Lee, JH; Lee, KH; Lee, SM; Lee, WS; Lim, SN; Moon, JH; Park, S; Ryoo, HM; Shin, HJ; Sohn, SK; Won, JH; Yang, DH; Yun, SC | 1 |
| Burger, JA; Champlin, R; Cortes, JE; Estrov, Z; Faderl, S; Ferrajoli, A; Garcia-Manero, G; Garris, R; Huang, X; Jabbour, E; Kantarjian, HM; Kebriaei, P; McCue, DA; O'Brien, SM; Ravandi, F; Rytting, ME; Thomas, DM; Verstovsek, S; Wierda, WG | 1 |
| Cortes, JE; Garcia-Manero, G; Garris, R; Issa, GC; Jabbour, E; Kantarjian, H; Luthra, R; O'Brien, SM; Patel, K; Ravandi, F; Sasaki, K; Short, NJ; Thomas, D | 1 |
| Fujita, N; Inaba, T; Nakatani, T; Nishimura, H; Saito, J; Uchiyama, H; Yamamoto, M; Yamane, Y | 1 |
| Hackanson, B; Lübbert, M; Rückert, A | 1 |
| Intermesoli, T; Jenner, M; Krishnan, S; Lister, A; MacDougall, F; Rohatiner, A | 1 |
| Hamilton, MS; Hunter, H; Kerr, JP; Tucker, D; Wickham, C | 1 |
| Chen, SN; Dai, HP; Gong, YL; Pan, JL; Wu, DP; Wu, LL; Wu, YF; Xue, YQ; Zhang, J | 1 |
| Atenafu, EG; Brandwein, JM; Craddock, KJ; Gupta, V; Kennedy, JA; Lipton, JH; Messner, HA; Minden, MD; Schimmer, AD; Schuh, AC; Yee, KW | 1 |
| Beran, M; Dong, L; Kantarjian, HM; Keating, MJ; Onida, F; Scappini, B; Verstovsek, S | 1 |
| Al-Ali, HK; Bumm, T; Deininger, MW; Franke, C; Friedrich, T; Hennig, E; Krahl, R; Krohn, K; Leiblein, S; Müller, C; Niederwieser, D; Schmidt, E; Shepherd, P | 1 |
| Abgrall, JF; Berthou, C; Braekeleer, MD; Bris, MJ; Calvez, GL; Herry, A; Marion, V; Morel, F | 1 |
| Camera, A; Cimino, G; Cuneo, A; Foà, R; Izzo, B; Mancini, M; Mandelli, F; Martinelli, G; Mecucci, C; Pane, F; Picardi, M; Quintarelli, C; Rotoli, B; Saglio, G; Salvatore, F; Specchia, G; Vitale, A | 1 |
| Cortes, J; Dewald, GW; Kantarjian, HM; Litzow, ML; Mauro, MJ; Talpaz, M; Tefferi, A | 1 |
| Aleskog, A; Barbany, G; Björnberg, A; Hallböök, H; Larsson, R; Lindhagen, E; Sundström, C | 1 |
| Fay, M; Goldman, J; Murphy, PT; O'Donnell, R; Quinn, J; Swords, R | 1 |
| Irving, I; Kennedy, GA; McCarthy, C; Perel, JM; Walker, O; Williams, B | 1 |
| Adamczyk-Cioch, M; Dmoszyńska, A; Haus, O; Hołowiecki, J; Jakubas, B; Jedrzejczak, WW; Konopka, L; Kuliczkowski, K; Mazur, G; Nowak, K; Paluszewska, M; Pałynyczko, G; Pluta, A; Robak, T; Skotnicki, A; Wawrzyniak, E; Wierzbowska, A; Wrzesień-Kuś, A; Zwolińska, M | 1 |
| Urabe, A | 1 |
| Buzyn, A; Cayuela, JM; Chalandon, Y; de Labarthe, A; Delabesse, E; Dombret, H; Escoffre, M; Huguet-Rigal, F; Ifrah, N; Lhéritier, V; MacIntyre, E; Maury, S; Pigneux, A; Réa, D; Reman, O; Rousselot, P; Thomas, X; Vekemans, MC; Vernant, JP; Witz, F | 1 |
| Abruzzo, LV; Bobadilla, D; Cortes, J; Gibbons, DL; Kantarjian, H; Quintás-Cardama, A; Slovak, ML | 1 |
| Carella, AM; Ferrero, R; Frassoni, F; Podestá, M; Pollicardo, N; Pungolino, E; Soracco, M | 1 |
| Hirano, M; Kojima, S; Miyamura, K; Morishima, Y; Morishita, Y; Ohno, R; Sao, H; Sobue, R; Tanimoto, M; Ueda, R | 1 |
| Chalmers, EA; Clarke, R; Franklin, IM; Goldstone, AH; Hepplestone, A; Kelsey, S; Sharp, S; Sproul, AM; Tansey, P; Watson, W | 1 |
| Canellos, GP; Cannistra, SA; Griffin, JD; Robertson, MJ; Tantravahi, R | 1 |
| Boogaerts, M; Bosly, A; Carli, MG; Castoldi, G; Cuneo, A; Demuynck, H; Doyen, C; Ferrant, A; Michaux, JL; Piva, N | 1 |
| Babacan, E; Bökesoy, I; Cavdar, AO; Gözdaşoğlu, S; Pamĭr, A; Sunguroğlu, A; Tanindi, S; Türker, A; Unal, E; Yavuz, G | 1 |
| Ohyashiki, JH; Ohyashiki, K; Toyama, K | 1 |
| Bradstock, K; Brisco, J; Enno, A; Hughes, E; McCaul, K; Morley, AA; Neoh, SH; Sykes, PJ; Szer, J | 1 |
| Aulitzky, WE; Busemann, C; Huber, C; Huhn, D; Kolbe, K; Neubauer, A; Peschel, C; Schleiermacher, E; Schneller, F; Siegert, W | 1 |
| Hall, JL; Hamblin, TJ; Myint, H; Ross, FM | 1 |
| Deane, M; Foroni, L; Galactowicz, G; Hoffbrand, AV; Koh, M; Lawler, M; Prentice, HG; Secker-Walker, L | 1 |
| Guilhot, F | 1 |
| Dewald, GW; Silver, RT; Wyatt, WA | 1 |
| Hawrylecka, D; Sacha, T; Skotnicki, AB | 1 |
| Cornelissen, JJ; Hagemeijer, A; Janssen, JJ; Nieuwint, AW; Ossenkoppele, GJ; Schuurhuis, GJ; Släter, R; van den Berg, E; van der Holt, B; van Rijn, RS; Vellenga, E; Verhoef, GE | 1 |
| Fricová, M; Guman, T; Hlebasková, M; Kafková, A; Mudronová, B; Raffac, S; Stecová, N; Svorcová, E; Tóthová, E | 1 |
| Cavenagh, JD; Kelsey, SM; Lillington, DM; McBride, NC; Murrell, C; Newland, AC | 1 |
| Dachselt, K; Deininger, M; Doepper, J; Dölken, G; Edel, E; Fiedler, F; Franke, A; Freund, M; Helbig, W; Herold, M; Hoffmann, FA; Kettner, E; Krahl, R; Lange, T; Leiblein, S; Niederwieser, D; Pasold, R; Pönisch, W; Richter, P; Schultze, W; Schwalbe, E; Schwarzer, A; Steglich, J; Subert, R; Uhle, R; von Grünhagen, U; Winkelmann, C | 1 |
| Arellano-Rodrigo, E; Carreras, E; Cervantes, F; Espinet, B; Hernández-Boluda, JC; Lloveras, E; Marín, P; Montserrat, E; Ocejo, A; Rovira, M; Solé, F | 1 |
| Albitar, M; Cortes, J; Faderl, S; Garcia-Manero, G; Giles, FJ; Kantarjian, HM; O'Brien, S; Resta, D; Rios, MB; Shan, J; Talpaz, M; Thomas, DA | 1 |
| Karle, H; Nielsen, H; Nielsen, JL | 1 |
| Carella, AM; Carlier, P; Defferrari, R; Frassoni, F; Gaozza, E; Guerrasio, A; Lercari, G; Raffo, MR; Sessarego, M; Valbonesi, M | 1 |
| Gong, JX; Gu, J; Guo, Y; Lin, BJ; Lu, DR; Lu, DW; Wang, MH; Xue, YQ; Zhu, WY | 1 |
| Anger, B; Heimpel, H | 1 |
| Bigner, SH; Gockerman, JP; Sokal, JE | 1 |
| Ballesta, F; Cervantes, F; Milá, M; Rozman, C | 1 |
| Bligham, G; Freireich, EJ; Gehan, E; Hester, JP; Kantarjian, HM; Keating, MJ; McCredie, KB; Smith, TL; Talpaz, M; Walters, RS | 1 |
7 review(s) available for cytarabine and Ph 1 Chromosome
| Article | Year |
|---|---|
Hyperleukocytotic secondary acute myeloid leukemia (AML) with sole monosomy 7 as sequela of Philadelphia-chromosome positive chronic myeloid leukemia (CML).
Topics: Aged; Anemia, Refractory, with Excess of Blasts; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Chromosome Deletion; Chromosomes, Human, Pair 7; Cytarabine; Disease Progression; Fatal Outcome; Humans; Imatinib Mesylate; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Leukocytosis; Male; Monosomy; Philadelphia Chromosome; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Selection, Genetic | 2009 |
Chronic myeloid leukemia: current application of cytogenetics and molecular testing for diagnosis and treatment.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Benzamides; Cytarabine; Genes, abl; Humans; Imatinib Mesylate; In Situ Hybridization, Fluorescence; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplasm, Residual; Philadelphia Chromosome; Piperazines; Prognosis; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; Stem Cell Transplantation; Treatment Outcome | 2005 |
[Chronic myelogenous leukemia].
Topics: Antineoplastic Agents; Benzamides; Cytarabine; Drug Therapy, Combination; Genes, abl; Humans; Imatinib Mesylate; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Philadelphia Chromosome; Piperazines; Pyrimidines | 2006 |
Mobilisation of Ph-negative peripheral blood stem cells in CML with idarubicin and cytarabine.
Topics: Cell Separation; Cytarabine; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Idarubicin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Philadelphia Chromosome; Transplantation, Autologous | 1994 |
Clinical review on features and cytogenetic patterns in adult acute myeloid leukemia with lymphoid markers.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aneuploidy; Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chromosome Aberrations; Cytarabine; DNA Nucleotidylexotransferase; Etoposide; Female; Gene Rearrangement; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Philadelphia Chromosome; Remission Induction; Vindesine | 1993 |
Therapy for Philadelphia chromosome-positive acute lymphoblastic leukemia: possible use of interferon on the basis of some novel concepts.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Gene Rearrangement; Genes, abl; Humans; Immunologic Factors; Interferon-alpha; Male; Mercaptopurine; Middle Aged; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Vincristine | 1993 |
[Autologous hemopoietic stem cell transplantation in treatment of chronic myelogenous leukemia].
Topics: Algorithms; Cytarabine; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Philadelphia Chromosome; Tissue Donors | 1999 |
13 trial(s) available for cytarabine and Ph 1 Chromosome
| Article | Year |
|---|---|
Long-term follow-up of imatinib plus combination chemotherapy in patients with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Imatinib Mesylate; Induction Chemotherapy; Male; Methotrexate; Middle Aged; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Recurrence; Remission Induction; Survival Analysis; Transplantation, Homologous; Vincristine | 2015 |
Long-term follow-up of a phase 2 study of chemotherapy plus dasatinib for the initial treatment of patients with Philadelphia chromosome-positive acute lymphoblastic leukemia.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dasatinib; Dexamethasone; Doxorubicin; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Neoplasm, Residual; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Analysis; Treatment Outcome; Vincristine; Young Adult | 2015 |
Efficacy of an intensive post-induction chemotherapy regimen for adult patients with Philadelphia chromosome-negative acute lymphoblastic leukemia, given predominantly in the out-patient setting.
Topics: Adolescent; Adult; Aged; Ambulatory Care Facilities; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Germany; Humans; Male; Middle Aged; Outpatients; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Treatment Outcome; Young Adult | 2011 |
Significant reduction of the hybrid BCR/ABL transcripts after induction and consolidation therapy is a powerful predictor of treatment response in adult Philadelphia-positive acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Fusion Proteins, bcr-abl; Humans; Male; Middle Aged; Neoplasm, Residual; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Predictive Value of Tests; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; Vincristine | 2005 |
Imatinib combined with induction or consolidation chemotherapy in patients with de novo Philadelphia chromosome-positive acute lymphoblastic leukemia: results of the GRAAPH-2003 study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Imatinib Mesylate; Male; Middle Aged; Mitoxantrone; Neoplasm, Residual; Philadelphia Chromosome; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Remission Induction; Survival Analysis; Transplantation, Homologous | 2007 |
Idarubicin, intermediate-dose cytarabine, etoposide, and granulocyte-colony-stimulating factor are able to recruit CD34+/HLA-DR- cells during early hematopoietic recovery in accelerated and chronic phases of chronic myeloid leukemia.
Topics: Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; HLA-DR Antigens; Humans; Idarubicin; Interferon-alpha; Leukapheresis; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Middle Aged; Philadelphia Chromosome; Treatment Outcome | 1994 |
Autologous BMT in high risk patients with CALLA-positive ALL: possible efficacy of ex vivo marrow leukemia cell purging with monoclonal antibodies and complement.
Topics: Adolescent; Adult; Antibodies, Monoclonal; Base Sequence; Biomarkers, Tumor; Bone Marrow; Bone Marrow Purging; Bone Marrow Transplantation; Child; Child, Preschool; Complement System Proteins; Cyclophosphamide; Cytarabine; Female; Fusion Proteins, bcr-abl; Granulocyte Colony-Stimulating Factor; Humans; Male; Melphalan; Middle Aged; Molecular Sequence Data; Neoplasm Proteins; Neoplastic Stem Cells; Philadelphia Chromosome; Polymerase Chain Reaction; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Risk Factors; Survival Analysis; Transplantation, Autologous; Treatment Outcome; Whole-Body Irradiation | 1993 |
Relationship between minimal residual disease and outcome in adult acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Bone Marrow Transplantation; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Neoplasm; Etoposide; Gene Rearrangement, B-Lymphocyte, Heavy Chain; Humans; Mercaptopurine; Methotrexate; Middle Aged; Neoplasm, Residual; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Survival Analysis; Treatment Outcome; Vincristine | 1996 |
Preliminary results of stem cell mobilization in chronic myeloid leukemia with a moderate intensity chemotherapy regimen and G-CSF or G-CSF plus IL-3.
Topics: Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Drug Resistance; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Idarubicin; Interferon-alpha; Interleukin-3; Leukapheresis; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Chronic-Phase; Middle Aged; Philadelphia Chromosome | 1996 |
Mobilisation of haemopoietic progenitors in CML: a second course of intensive chemotherapy does not improve Ph-negativity in stem cell harvests.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Female; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Philadelphia Chromosome; Transplantation, Autologous | 2000 |
Autologous transplantation with Philadelphia-negative progenitor cells for patients with chronic myeloid leukaemia (CML) failing to attain a cytogenetic response to alpha interferon.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Idarubicin; Interferon-alpha; Leukemia, Myeloid, Chronic-Phase; Male; Middle Aged; Philadelphia Chromosome; Prospective Studies; Survival Rate; Treatment Outcome | 2000 |
Chemotherapy for mobilisation of Ph-negative progenitor cells from patients with CML: impact of different mobilisation regimens.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Female; Graft Survival; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Idarubicin; Interferon-alpha; Leukapheresis; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Philadelphia Chromosome | 2001 |
Imatinib mesylate (STI571) therapy for Philadelphia chromosome-positive chronic myelogenous leukemia in blast phase.
Topics: Adult; Antineoplastic Agents; Benzamides; Blast Crisis; Blood Cell Count; Cytarabine; Cytogenetic Analysis; Enzyme Inhibitors; Follow-Up Studies; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Middle Aged; Philadelphia Chromosome; Piperazines; Prognosis; Pyrimidines; Survival Rate; Treatment Outcome | 2002 |
35 other study(ies) available for cytarabine and Ph 1 Chromosome
| Article | Year |
|---|---|
Drug-induced aseptic meningitis in a Ph+ ALL patient with meningeal involvement.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Meningitis, Aseptic; Methotrexate; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2020 |
Successful use of trametinib and dasatinib combined with chemotherapy in the treatment of Ph-positive B-cell acute lymphoblastic leukemia: A case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Azathioprine; Child; Consolidation Chemotherapy; Cyclophosphamide; Cytarabine; Dasatinib; Humans; Maintenance Chemotherapy; Male; Pancreatitis; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyridones; Pyrimidinones; Treatment Outcome | 2021 |
The novel phospholipid mimetic KPC34 is highly active against preclinical models of Philadelphia chromosome positive acute lymphoblastic leukemia.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cytarabine; Deoxycytidine; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gemcitabine; Glycerophosphates; Humans; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Transplantation; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase C; Random Allocation; Tumor Burden | 2017 |
Primary Philadelphia chromosome positive acute myeloid leukemia: A case report.
Topics: Antineoplastic Agents; Bone Marrow Examination; Cytarabine; Dasatinib; Flow Cytometry; Fusion Proteins, bcr-abl; Humans; Idarubicin; Karyotype; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Multiple Organ Failure; Mutation; Philadelphia Chromosome | 2018 |
Detection of MRD may predict the outcome of patients with Philadelphia chromosome-positive ALL treated with tyrosine kinase inhibitors plus chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cyclophosphamide; Cytarabine; Dasatinib; Dexamethasone; Doxorubicin; Female; Flow Cytometry; Follow-Up Studies; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Immunoglobulin Heavy Chains; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm, Residual; Philadelphia Chromosome; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Pyrimidines; Real-Time Polymerase Chain Reaction; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Thiazoles; Vincristine; Young Adult | 2013 |
Allogeneic stem cell transplantation for Philadelphia chromosome-positive acute myeloid leukemia.
Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Benzamides; Consolidation Chemotherapy; Cyclophosphamide; Cytarabine; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Imatinib Mesylate; Immunosuppressive Agents; Induction Chemotherapy; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Philadelphia Chromosome; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Transplantation, Homologous; Treatment Outcome; Young Adult | 2014 |
Efficacy of low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor (CAG regimen) compared to Hyper-CVAD regimen as salvage chemotherapy in relapsed/refractory Philadelphia chromosome-negative acute lymphoblastic leuk
Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Male; Middle Aged; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Rate; Vincristine; Young Adult | 2015 |
Impact of complete molecular response on survival in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Female; Follow-Up Studies; Fusion Proteins, bcr-abl; Humans; Infant; Male; Methotrexate; Neoplasm, Residual; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Rate; Vincristine | 2016 |
Human leukocyte antigen-DR negative de novo acute myeloid leukemia with Philadelphia chromosome.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; HLA-DR Antigens; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Philadelphia Chromosome; Remission Induction | 2008 |
Lytic bone disease as the presenting feature of Philadelphia-positive monosomy 7 myelodysplasia progressing to acute myeloid leukaemia.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Diseases; Chromosome Deletion; Chromosomes, Human, Pair 19; Chromosomes, Human, Pair 7; Chromosomes, Human, Pair 9; Cytarabine; Humans; Idarubicin; Imatinib Mesylate; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Pain; Philadelphia Chromosome; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Radiography; Vidarabine | 2012 |
p210 BCR/ABL1 as a secondary change in a patient with acute myelomonocytic leukemia (M4Eo) with inv(16).
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Chromosome Inversion; Chromosomes, Human, Pair 16; Combined Modality Therapy; Cytarabine; Fusion Proteins, bcr-abl; Humans; Idarubicin; Imatinib Mesylate; In Situ Hybridization, Fluorescence; Leukemia, Myelomonocytic, Acute; Male; Oncogene Proteins, Fusion; Peripheral Blood Stem Cell Transplantation; Philadelphia Chromosome; Piperazines; Pyrimidines; Remission Induction | 2012 |
Treatment outcomes following leukemic transformation in Philadelphia-negative myeloproliferative neoplasms.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; Combined Modality Therapy; Cytarabine; Decitabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Myeloproliferative Disorders; Philadelphia Chromosome; Registries; Survival Analysis; Transplantation, Homologous; Treatment Outcome; Young Adult | 2013 |
In vitro effects of STI 571-containing drug combinations on the growth of Philadelphia-positive chronic myelogenous leukemia cells.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cytarabine; Dose-Response Relationship, Drug; Drug Synergism; Harringtonines; Homoharringtonine; Imatinib Mesylate; In Vitro Techniques; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Philadelphia Chromosome; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Tumor Cells, Cultured; Tumor Stem Cell Assay | 2002 |
Emergence of clonal cytogenetic abnormalities in Ph- cells in some CML patients in cytogenetic remission to imatinib but restoration of polyclonal hematopoiesis in the majority.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Benzamides; Blood Cells; Bone Marrow Cells; Clone Cells; Cohort Studies; Cytarabine; Dosage Compensation, Genetic; Enzyme Inhibitors; Female; Fusion Proteins, bcr-abl; Hematopoiesis; Humans; Idarubicin; Imatinib Mesylate; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Middle Aged; Myelodysplastic Syndromes; Philadelphia Chromosome; Piperazines; Pyrimidines; Receptors, Androgen; Remission Induction | 2003 |
Double minutes containing amplified bcr-abl fusion gene in a case of chronic myeloid leukemia treated by imatinib.
Topics: Aneuploidy; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Blast Crisis; Chromosome Aberrations; Chromosome Painting; Combined Modality Therapy; Cytarabine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Fatal Outcome; Fusion Proteins, bcr-abl; Gene Amplification; Humans; Hydroxyurea; Imatinib Mesylate; Interferon-alpha; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Neoplasm Proteins; Peripheral Blood Stem Cell Transplantation; Philadelphia Chromosome; Piperazines; Pyrimidines; Transplantation, Autologous | 2003 |
In vitro activity of imatinib in cells from patients with adult acute lymphoblastic leukemia.
Topics: Adult; Antineoplastic Agents; Asparaginase; Benzamides; Cell Survival; Cytarabine; Daunorubicin; Drug Interactions; Drug Screening Assays, Antitumor; Fluorometry; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Immunosuppressive Agents; Mercaptopurine; Philadelphia Chromosome; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Pyrimidines; Tumor Cells, Cultured; Vincristine | 2005 |
CML clonal evolution with resistance to single agent imatinib therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cell Transformation, Neoplastic; Clone Cells; Cytarabine; Drug Resistance, Neoplasm; Humans; Hydroxyurea; Imatinib Mesylate; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Philadelphia Chromosome; Piperazines; Pyrimidines; Remission Induction; Treatment Failure; Trisomy | 2005 |
Clinical significance of development of Philadelphia-chromosome negative clones in patients with chronic myeloid leukemia treated with imatinib mesylate.
Topics: Acute Disease; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Marrow; Clone Cells; Cytarabine; Disease Progression; Fatal Outcome; Fusion Proteins, bcr-abl; Granulocyte Colony-Stimulating Factor; Humans; Hydroxyurea; Imatinib Mesylate; In Situ Hybridization, Fluorescence; Interferons; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Leukemia, Myeloid, Chronic-Phase; Male; Middle Aged; Neoplastic Stem Cells; Philadelphia Chromosome; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Selection, Genetic; Vidarabine | 2005 |
Outcome of treatment in adults with Philadelphia chromosome-positive and/or BCR-ABL--positive acute lymphoblastic leukemia-retrospective analysis of Polish Adult Leukemia Group (PALG).
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Fusion Proteins, bcr-abl; Hematopoietic Stem Cell Transplantation; Humans; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mercaptopurine; Methotrexate; Middle Aged; Philadelphia Chromosome; Poland; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Retrospective Studies; Treatment Outcome | 2006 |
Association of 3q21q26 syndrome and late-appearing Philadelphia chromosome in acute myeloid leukemia.
Topics: Chromosomes, Human, Pair 3; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Philadelphia Chromosome; Syndrome; Time Factors | 2008 |
Hematologic remission and cytogenetic improvement after treatment of stable-phase chronic myelogenous leukemia with continuous infusion of low-dose cytarabine.
Topics: Adult; Aged; Bone Marrow; Cytarabine; Cytogenetics; Female; Humans; Infusion Pumps; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Philadelphia Chromosome; Remission Induction; Stem Cells | 1993 |
Orbito-ocular granulocytic sarcoma (OOGS) and acute myeloblastic leukemia (AML) with duplication of Philadelphia chromosome.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cytarabine; Dexamethasone; Doxorubicin; Etoposide; Eye Neoplasms; Humans; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Multigene Family; Neoplasms, Multiple Primary; Orbital Neoplasms; Philadelphia Chromosome; Thioguanine | 1993 |
Early transformation to acute myeloblastic leukaemia with the acquisition of inv(16) in Ph positive chronic granulocytic leukaemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Disorders; Chromosome Inversion; Chromosome Mapping; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Cytarabine; Fatal Outcome; Humans; Idarubicin; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Philadelphia Chromosome | 1997 |
FLAG-idarubicin and allogeneic stem cell transplantation for Ph-positive ALL beyond first remission.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Male; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Transplantation, Homologous; Treatment Outcome; Vidarabine | 1998 |
[Interferon-alpha in the treatment of chronic myeloid leukemia].
Topics: Adult; Age Factors; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Bone Marrow Transplantation; Busulfan; Cause of Death; Cytarabine; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Middle Aged; Philadelphia Chromosome | 1999 |
Atypical BCR and ABL D-FISH patterns in chronic myeloid leukemia and their possible role in therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Cytarabine; Genes, abl; Humans; In Situ Hybridization, Fluorescence; Interferon alpha-2; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Oncogene Proteins; Philadelphia Chromosome; Predictive Value of Tests; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcr; Recombinant Proteins; Sensitivity and Specificity; Translocation, Genetic | 1999 |
[Hematologic and cytogenetic response to treatment in patients with chronic myeloid leukemia].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Philadelphia Chromosome | 2000 |
Collection of Philadelphia-negative stem cells using recombinant human granulocyte colony-stimulating factor in chronic myeloid leukemia patients treated with alpha-interferon.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Blood Component Removal; Bone Marrow Purging; Busulfan; Cytarabine; Feasibility Studies; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Hydroxyurea; Immunologic Factors; Interferons; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocytosis; Male; Middle Aged; Neoplastic Cells, Circulating; Pain; Philadelphia Chromosome; Recombinant Proteins; Remission Induction; Safety; Transplantation, Autologous; Treatment Outcome | 2002 |
Initial cytoreduction by mitoxantrone and cytarabine has no impact on the outcome of interferon-alfa-2b therapy in chronic myelogenous leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Interferon alpha-2; Interferon-alpha; Leukemia, Myeloid, Chronic-Phase; Longitudinal Studies; Middle Aged; Mitoxantrone; Philadelphia Chromosome; Pilot Projects; Recombinant Proteins; Remission Induction | 1992 |
Therapy of acute phase chronic myelogenous leukemia with intensive chemotherapy, blood cell autotransplant and cyclosporine A.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Combined Modality Therapy; Cyclosporins; Cytarabine; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Accelerated Phase; Male; Middle Aged; Philadelphia Chromosome; Transplantation, Autologous | 1991 |
A case of basophilic leukemia bearing simultaneous translocations t(8;21) and t(9;22).
Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 8; Chromosomes, Human, Pair 9; Cyclophosphamide; Cytarabine; Drug Combinations; Humans; Karyotyping; Leukemia, Basophilic, Acute; Male; Middle Aged; Philadelphia Chromosome; Prednisone; Translocation, Genetic; Vincristine | 1991 |
Daunomycin, cytosin-arabinoside and VP-16 (DAV) for myeloid blast crisis of CML.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Philadelphia Chromosome; Thioguanine | 1989 |
Evidence for a selective antileukemic effect of cytosine arabinoside in chronic granulocytic leukemia.
Topics: Adult; Bone Marrow; Cytarabine; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Philadelphia Chromosome; Pilot Projects; Remission Induction | 1988 |
[Cytogenetic and therapeutic results of a protocol including splenectomy and intensive polychemotherapy in Ph'-positive chronic myeloid leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Clone Cells; Combined Modality Therapy; Cytarabine; Humans; Leukemia, Myeloid; Philadelphia Chromosome; Prednisone; Splenectomy; Thioguanine; Vincristine | 1986 |
Chronic myelogenous leukemia: a multivariate analysis of the associations of patient characteristics and therapy with survival.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Basophils; Blood Cell Count; Body Weight; Bone Marrow Cells; Busulfan; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Combinations; Female; Hemoglobins; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Middle Aged; Philadelphia Chromosome; Prednisone; Prognosis; Risk; Vincristine | 1985 |